Amino acid dipepetide frequency for Anaerosporobacter mobilis DSM 15930

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.383AlaAla: 4.383 ± 0.075	0.904AlaCys: 0.904 ± 0.026	3.428AlaAsp: 3.428 ± 0.057	3.716AlaGlu: 3.716 ± 0.063	2.658AlaPhe: 2.658 ± 0.054	4.247AlaGly: 4.247 ± 0.073	0.849AlaHis: 0.849 ± 0.027	5.785AlaIle: 5.785 ± 0.077	4.903AlaLys: 4.903 ± 0.066	5.582AlaLeu: 5.582 ± 0.077	1.917AlaMet: 1.917 ± 0.044	3.055AlaAsn: 3.055 ± 0.046	1.515AlaPro: 1.515 ± 0.033	1.566AlaGln: 1.566 ± 0.035	2.248AlaArg: 2.248 ± 0.045	3.795AlaSer: 3.795 ± 0.061	3.645AlaThr: 3.645 ± 0.07	4.491AlaVal: 4.491 ± 0.062	0.5AlaTrp: 0.5 ± 0.019	2.694AlaTyr: 2.694 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.687CysAla: 0.687 ± 0.021	0.229CysCys: 0.229 ± 0.014	0.784CysAsp: 0.784 ± 0.026	0.85CysGlu: 0.85 ± 0.029	0.6CysPhe: 0.6 ± 0.021	1.135CysGly: 1.135 ± 0.037	0.239CysHis: 0.239 ± 0.014	1.206CysIle: 1.206 ± 0.03	1.022CysLys: 1.022 ± 0.027	1.061CysLeu: 1.061 ± 0.027	0.428CysMet: 0.428 ± 0.02	0.79CysAsn: 0.79 ± 0.025	0.461CysPro: 0.461 ± 0.027	0.329CysGln: 0.329 ± 0.014	0.457CysArg: 0.457 ± 0.016	0.891CysSer: 0.891 ± 0.029	0.698CysThr: 0.698 ± 0.024	0.803CysVal: 0.803 ± 0.028	0.106CysTrp: 0.106 ± 0.009	0.596CysTyr: 0.596 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.275AspAla: 3.275 ± 0.059	0.827AspCys: 0.827 ± 0.025	2.886AspAsp: 2.886 ± 0.049	4.588AspGlu: 4.588 ± 0.058	2.626AspPhe: 2.626 ± 0.042	3.843AspGly: 3.843 ± 0.068	0.771AspHis: 0.771 ± 0.022	5.255AspIle: 5.255 ± 0.071	4.406AspLys: 4.406 ± 0.057	4.613AspLeu: 4.613 ± 0.055	1.764AspMet: 1.764 ± 0.032	3.074AspAsn: 3.074 ± 0.039	1.37AspPro: 1.37 ± 0.034	1.414AspGln: 1.414 ± 0.029	1.947AspArg: 1.947 ± 0.04	3.583AspSer: 3.583 ± 0.048	3.503AspThr: 3.503 ± 0.053	3.668AspVal: 3.668 ± 0.05	0.564AspTrp: 0.564 ± 0.017	2.927AspTyr: 2.927 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	4.613GluAla: 4.613 ± 0.065	0.786GluCys: 0.786 ± 0.023	4.411GluAsp: 4.411 ± 0.067	7.284GluGlu: 7.284 ± 0.091	2.848GluPhe: 2.848 ± 0.051	4.133GluGly: 4.133 ± 0.06	1.227GluHis: 1.227 ± 0.029	5.992GluIle: 5.992 ± 0.081	6.143GluLys: 6.143 ± 0.069	6.886GluLeu: 6.886 ± 0.075	2.105GluMet: 2.105 ± 0.043	4.289GluAsn: 4.289 ± 0.059	1.624GluPro: 1.624 ± 0.035	2.863GluGln: 2.863 ± 0.056	2.927GluArg: 2.927 ± 0.05	3.791GluSer: 3.791 ± 0.057	3.579GluThr: 3.579 ± 0.053	5.057GluVal: 5.057 ± 0.06	0.664GluTrp: 0.664 ± 0.021	3.611GluTyr: 3.611 ± 0.069	0.0GluXaa: 0.0 ± 0.0
Phe	2.623PheAla: 2.623 ± 0.046	0.633PheCys: 0.633 ± 0.022	2.711PheAsp: 2.711 ± 0.04	2.81PheGlu: 2.81 ± 0.051	1.703PhePhe: 1.703 ± 0.044	2.783PheGly: 2.783 ± 0.047	0.73PheHis: 0.73 ± 0.02	3.396PheIle: 3.396 ± 0.056	2.446PheLys: 2.446 ± 0.041	3.621PheLeu: 3.621 ± 0.062	1.09PheMet: 1.09 ± 0.027	2.153PheAsn: 2.153 ± 0.044	1.138PhePro: 1.138 ± 0.033	1.157PheGln: 1.157 ± 0.03	1.417PheArg: 1.417 ± 0.032	2.874PheSer: 2.874 ± 0.048	2.598PheThr: 2.598 ± 0.052	2.808PheVal: 2.808 ± 0.048	0.395PheTrp: 0.395 ± 0.017	1.861PheTyr: 1.861 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	3.995GlyAla: 3.995 ± 0.066	0.958GlyCys: 0.958 ± 0.028	3.311GlyAsp: 3.311 ± 0.055	4.279GlyGlu: 4.279 ± 0.052	2.991GlyPhe: 2.991 ± 0.054	4.035GlyGly: 4.035 ± 0.074	1.039GlyHis: 1.039 ± 0.032	6.115GlyIle: 6.115 ± 0.067	5.146GlyLys: 5.146 ± 0.062	5.116GlyLeu: 5.116 ± 0.066	1.997GlyMet: 1.997 ± 0.045	3.383GlyAsn: 3.383 ± 0.061	1.06GlyPro: 1.06 ± 0.034	1.7GlyGln: 1.7 ± 0.031	2.226GlyArg: 2.226 ± 0.047	3.697GlySer: 3.697 ± 0.058	3.971GlyThr: 3.971 ± 0.06	4.557GlyVal: 4.557 ± 0.069	0.589GlyTrp: 0.589 ± 0.023	3.317GlyTyr: 3.317 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	0.881HisAla: 0.881 ± 0.027	0.268HisCys: 0.268 ± 0.015	0.851HisAsp: 0.851 ± 0.023	1.023HisGlu: 1.023 ± 0.026	0.722HisPhe: 0.722 ± 0.022	1.075HisGly: 1.075 ± 0.034	0.35HisHis: 0.35 ± 0.019	1.467HisIle: 1.467 ± 0.034	1.069HisLys: 1.069 ± 0.027	1.32HisLeu: 1.32 ± 0.03	0.482HisMet: 0.482 ± 0.016	0.891HisAsn: 0.891 ± 0.021	0.578HisPro: 0.578 ± 0.021	0.502HisGln: 0.502 ± 0.019	0.617HisArg: 0.617 ± 0.021	0.997HisSer: 0.997 ± 0.026	0.887HisThr: 0.887 ± 0.024	1.011HisVal: 1.011 ± 0.031	0.165HisTrp: 0.165 ± 0.011	0.754HisTyr: 0.754 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.864IleAla: 5.864 ± 0.081	1.265IleCys: 1.265 ± 0.03	5.131IleAsp: 5.131 ± 0.063	5.999IleGlu: 5.999 ± 0.074	3.072IlePhe: 3.072 ± 0.058	5.503IleGly: 5.503 ± 0.083	1.493IleHis: 1.493 ± 0.033	7.085IleIle: 7.085 ± 0.1	5.878IleLys: 5.878 ± 0.06	7.552IleLeu: 7.552 ± 0.09	2.229IleMet: 2.229 ± 0.042	4.429IleAsn: 4.429 ± 0.058	3.166IlePro: 3.166 ± 0.055	2.7IleGln: 2.7 ± 0.04	3.314IleArg: 3.314 ± 0.051	5.574IleSer: 5.574 ± 0.068	5.459IleThr: 5.459 ± 0.077	5.763IleVal: 5.763 ± 0.075	0.652IleTrp: 0.652 ± 0.024	3.323IleTyr: 3.323 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	4.659LysAla: 4.659 ± 0.064	0.678LysCys: 0.678 ± 0.023	4.583LysAsp: 4.583 ± 0.059	7.835LysGlu: 7.835 ± 0.092	2.081LysPhe: 2.081 ± 0.036	4.218LysGly: 4.218 ± 0.061	1.128LysHis: 1.128 ± 0.031	5.695LysIle: 5.695 ± 0.074	6.716LysLys: 6.716 ± 0.087	6.228LysLeu: 6.228 ± 0.077	2.132LysMet: 2.132 ± 0.036	4.409LysAsn: 4.409 ± 0.058	1.929LysPro: 1.929 ± 0.037	2.899LysGln: 2.899 ± 0.041	2.967LysArg: 2.967 ± 0.049	4.127LysSer: 4.127 ± 0.063	4.075LysThr: 4.075 ± 0.058	5.173LysVal: 5.173 ± 0.072	0.561LysTrp: 0.561 ± 0.02	3.179LysTyr: 3.179 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	5.723LeuAla: 5.723 ± 0.066	1.342LeuCys: 1.342 ± 0.036	5.01LeuAsp: 5.01 ± 0.06	6.251LeuGlu: 6.251 ± 0.079	3.67LeuPhe: 3.67 ± 0.062	5.395LeuGly: 5.395 ± 0.072	1.426LeuHis: 1.426 ± 0.032	6.727LeuIle: 6.727 ± 0.085	6.014LeuLys: 6.014 ± 0.069	8.503LeuLeu: 8.503 ± 0.112	2.239LeuMet: 2.239 ± 0.041	4.516LeuAsn: 4.516 ± 0.062	3.075LeuPro: 3.075 ± 0.054	2.996LeuGln: 2.996 ± 0.05	3.413LeuArg: 3.413 ± 0.053	6.41LeuSer: 6.41 ± 0.07	5.053LeuThr: 5.053 ± 0.063	5.697LeuVal: 5.697 ± 0.064	0.667LeuTrp: 0.667 ± 0.023	3.626LeuTyr: 3.626 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	1.768MetAla: 1.768 ± 0.037	0.308MetCys: 0.308 ± 0.016	1.604MetAsp: 1.604 ± 0.03	2.198MetGlu: 2.198 ± 0.041	1.083MetPhe: 1.083 ± 0.026	1.719MetGly: 1.719 ± 0.034	0.445MetHis: 0.445 ± 0.016	2.3MetIle: 2.3 ± 0.038	2.678MetLys: 2.678 ± 0.044	2.48MetLeu: 2.48 ± 0.044	0.805MetMet: 0.805 ± 0.026	1.906MetAsn: 1.906 ± 0.037	0.946MetPro: 0.946 ± 0.026	1.002MetGln: 1.002 ± 0.026	1.101MetArg: 1.101 ± 0.025	1.747MetSer: 1.747 ± 0.031	1.422MetThr: 1.422 ± 0.037	1.856MetVal: 1.856 ± 0.037	0.189MetTrp: 0.189 ± 0.012	0.975MetTyr: 0.975 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.158AsnAla: 3.158 ± 0.053	0.701AsnCys: 0.701 ± 0.023	2.773AsnAsp: 2.773 ± 0.052	3.817AsnGlu: 3.817 ± 0.05	1.891AsnPhe: 1.891 ± 0.037	3.752AsnGly: 3.752 ± 0.064	0.953AsnHis: 0.953 ± 0.026	4.651AsnIle: 4.651 ± 0.06	4.147AsnLys: 4.147 ± 0.059	4.574AsnLeu: 4.574 ± 0.056	1.638AsnMet: 1.638 ± 0.035	3.251AsnAsn: 3.251 ± 0.072	2.131AsnPro: 2.131 ± 0.039	2.178AsnGln: 2.178 ± 0.043	2.133AsnArg: 2.133 ± 0.045	3.405AsnSer: 3.405 ± 0.051	3.318AsnThr: 3.318 ± 0.061	3.446AsnVal: 3.446 ± 0.055	0.489AsnTrp: 0.489 ± 0.019	2.567AsnTyr: 2.567 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	1.588ProAla: 1.588 ± 0.035	0.374ProCys: 0.374 ± 0.019	1.808ProAsp: 1.808 ± 0.032	2.279ProGlu: 2.279 ± 0.047	1.381ProPhe: 1.381 ± 0.033	1.61ProGly: 1.61 ± 0.035	0.459ProHis: 0.459 ± 0.018	2.565ProIle: 2.565 ± 0.047	1.822ProLys: 1.822 ± 0.032	2.361ProLeu: 2.361 ± 0.042	0.797ProMet: 0.797 ± 0.021	1.564ProAsn: 1.564 ± 0.033	0.558ProPro: 0.558 ± 0.024	0.762ProGln: 0.762 ± 0.02	0.831ProArg: 0.831 ± 0.026	1.87ProSer: 1.87 ± 0.04	1.802ProThr: 1.802 ± 0.041	2.209ProVal: 2.209 ± 0.042	0.268ProTrp: 0.268 ± 0.015	1.495ProTyr: 1.495 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	1.995GlnAla: 1.995 ± 0.046	0.352GlnCys: 0.352 ± 0.017	1.54GlnAsp: 1.54 ± 0.038	2.471GlnGlu: 2.471 ± 0.042	1.307GlnPhe: 1.307 ± 0.031	1.831GlnGly: 1.831 ± 0.036	0.414GlnHis: 0.414 ± 0.014	2.705GlnIle: 2.705 ± 0.043	2.361GlnLys: 2.361 ± 0.045	3.062GlnLeu: 3.062 ± 0.047	1.01GlnMet: 1.01 ± 0.027	1.705GlnAsn: 1.705 ± 0.034	0.791GlnPro: 0.791 ± 0.028	1.149GlnGln: 1.149 ± 0.038	1.216GlnArg: 1.216 ± 0.029	1.802GlnSer: 1.802 ± 0.034	1.783GlnThr: 1.783 ± 0.032	2.21GlnVal: 2.21 ± 0.043	0.27GlnTrp: 0.27 ± 0.017	1.582GlnTyr: 1.582 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	1.954ArgAla: 1.954 ± 0.04	0.525ArgCys: 0.525 ± 0.024	1.891ArgAsp: 1.891 ± 0.046	3.151ArgGlu: 3.151 ± 0.062	1.714ArgPhe: 1.714 ± 0.034	1.998ArgGly: 1.998 ± 0.037	0.59ArgHis: 0.59 ± 0.021	3.343ArgIle: 3.343 ± 0.055	2.965ArgLys: 2.965 ± 0.049	3.264ArgLeu: 3.264 ± 0.051	1.229ArgMet: 1.229 ± 0.032	2.101ArgAsn: 2.101 ± 0.037	0.93ArgPro: 0.93 ± 0.031	1.168ArgGln: 1.168 ± 0.029	1.526ArgArg: 1.526 ± 0.037	1.91ArgSer: 1.91 ± 0.038	1.975ArgThr: 1.975 ± 0.04	2.406ArgVal: 2.406 ± 0.043	0.317ArgTrp: 0.317 ± 0.015	1.921ArgTyr: 1.921 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	3.475SerAla: 3.475 ± 0.05	0.772SerCys: 0.772 ± 0.021	3.539SerAsp: 3.539 ± 0.057	4.116SerGlu: 4.116 ± 0.052	2.854SerPhe: 2.854 ± 0.041	4.343SerGly: 4.343 ± 0.061	0.952SerHis: 0.952 ± 0.025	5.664SerIle: 5.664 ± 0.064	4.801SerLys: 4.801 ± 0.059	5.487SerLeu: 5.487 ± 0.062	1.792SerMet: 1.792 ± 0.038	3.628SerAsn: 3.628 ± 0.06	1.515SerPro: 1.515 ± 0.032	1.84SerGln: 1.84 ± 0.032	2.184SerArg: 2.184 ± 0.041	4.328SerSer: 4.328 ± 0.069	3.647SerThr: 3.647 ± 0.055	4.219SerVal: 4.219 ± 0.059	0.572SerTrp: 0.572 ± 0.023	3.003SerTyr: 3.003 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	3.714ThrAla: 3.714 ± 0.061	0.696ThrCys: 0.696 ± 0.022	3.358ThrAsp: 3.358 ± 0.054	3.534ThrGlu: 3.534 ± 0.061	2.459ThrPhe: 2.459 ± 0.042	4.114ThrGly: 4.114 ± 0.073	0.863ThrHis: 0.863 ± 0.026	5.337ThrIle: 5.337 ± 0.073	4.219ThrLys: 4.219 ± 0.057	5.138ThrLeu: 5.138 ± 0.066	1.493ThrMet: 1.493 ± 0.036	3.189ThrAsn: 3.189 ± 0.054	1.885ThrPro: 1.885 ± 0.042	1.599ThrGln: 1.599 ± 0.033	1.877ThrArg: 1.877 ± 0.036	3.737ThrSer: 3.737 ± 0.06	3.711ThrThr: 3.711 ± 0.07	4.469ThrVal: 4.469 ± 0.059	0.532ThrTrp: 0.532 ± 0.019	2.791ThrTyr: 2.791 ± 0.057	0.0ThrXaa: 0.0 ± 0.0
Val	4.495ValAla: 4.495 ± 0.064	0.972ValCys: 0.972 ± 0.025	4.008ValAsp: 4.008 ± 0.066	4.714ValGlu: 4.714 ± 0.066	2.944ValPhe: 2.944 ± 0.053	4.199ValGly: 4.199 ± 0.064	0.996ValHis: 0.996 ± 0.029	5.895ValIle: 5.895 ± 0.076	4.943ValLys: 4.943 ± 0.067	6.085ValLeu: 6.085 ± 0.069	1.939ValMet: 1.939 ± 0.038	3.503ValAsn: 3.503 ± 0.057	2.084ValPro: 2.084 ± 0.04	1.74ValGln: 1.74 ± 0.032	2.305ValArg: 2.305 ± 0.042	4.696ValSer: 4.696 ± 0.056	4.478ValThr: 4.478 ± 0.077	5.004ValVal: 5.004 ± 0.067	0.54ValTrp: 0.54 ± 0.022	2.669ValTyr: 2.669 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.455TrpAla: 0.455 ± 0.021	0.134TrpCys: 0.134 ± 0.011	0.465TrpAsp: 0.465 ± 0.02	0.602TrpGlu: 0.602 ± 0.022	0.423TrpPhe: 0.423 ± 0.019	0.617TrpGly: 0.617 ± 0.023	0.147TrpHis: 0.147 ± 0.009	0.659TrpIle: 0.659 ± 0.022	0.653TrpLys: 0.653 ± 0.021	0.812TrpLeu: 0.812 ± 0.024	0.227TrpMet: 0.227 ± 0.014	0.603TrpAsn: 0.603 ± 0.02	0.185TrpPro: 0.185 ± 0.011	0.287TrpGln: 0.287 ± 0.017	0.308TrpArg: 0.308 ± 0.013	0.528TrpSer: 0.528 ± 0.02	0.446TrpThr: 0.446 ± 0.022	0.463TrpVal: 0.463 ± 0.017	0.125TrpTrp: 0.125 ± 0.009	0.402TrpTyr: 0.402 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.577TyrAla: 2.577 ± 0.037	0.647TyrCys: 0.647 ± 0.024	2.811TyrAsp: 2.811 ± 0.053	3.314TyrGlu: 3.314 ± 0.055	1.92TyrPhe: 1.92 ± 0.04	2.934TyrGly: 2.934 ± 0.053	0.839TyrHis: 0.839 ± 0.025	3.609TyrIle: 3.609 ± 0.057	2.939TyrLys: 2.939 ± 0.048	4.005TyrLeu: 4.005 ± 0.056	1.221TyrMet: 1.221 ± 0.034	2.537TyrAsn: 2.537 ± 0.041	1.459TyrPro: 1.459 ± 0.035	1.706TyrGln: 1.706 ± 0.029	1.861TyrArg: 1.861 ± 0.029	2.97TyrSer: 2.97 ± 0.055	2.664TyrThr: 2.664 ± 0.053	2.902TyrVal: 2.902 ± 0.047	0.379TyrTrp: 0.379 ± 0.017	2.365TyrTyr: 2.365 ± 0.053	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4544 proteins (1495280 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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