Amino acid dipepetide frequency for Gaeumannomyces tritici (strain R3-111a-1) (Wheat and barley take-all root rot fungus) (Gaeumannomyces graminis var. tritici)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.342AlaAla: 15.342 ± 0.103
1.315AlaCys: 1.315 ± 0.016
5.358AlaAsp: 5.358 ± 0.031
5.774AlaGlu: 5.774 ± 0.045
3.122AlaPhe: 3.122 ± 0.023
8.221AlaGly: 8.221 ± 0.044
2.048AlaHis: 2.048 ± 0.019
3.793AlaIle: 3.793 ± 0.028
4.13AlaLys: 4.13 ± 0.036
8.631AlaLeu: 8.631 ± 0.045
2.226AlaMet: 2.226 ± 0.021
2.868AlaAsn: 2.868 ± 0.023
6.649AlaPro: 6.649 ± 0.055
3.737AlaGln: 3.737 ± 0.028
6.916AlaArg: 6.916 ± 0.035
8.283AlaSer: 8.283 ± 0.046
6.127AlaThr: 6.127 ± 0.043
6.758AlaVal: 6.758 ± 0.038
1.363AlaTrp: 1.363 ± 0.017
2.038AlaTyr: 2.038 ± 0.017
0.0AlaXaa: 0.0 ± 0.0
Cys
1.135CysAla: 1.135 ± 0.013
0.31CysCys: 0.31 ± 0.009
0.662CysAsp: 0.662 ± 0.011
0.594CysGlu: 0.594 ± 0.011
0.535CysPhe: 0.535 ± 0.01
1.145CysGly: 1.145 ± 0.018
0.351CysHis: 0.351 ± 0.009
0.6CysIle: 0.6 ± 0.01
0.494CysLys: 0.494 ± 0.01
1.325CysLeu: 1.325 ± 0.017
0.285CysMet: 0.285 ± 0.007
0.399CysAsn: 0.399 ± 0.009
0.785CysPro: 0.785 ± 0.013
0.461CysGln: 0.461 ± 0.009
0.999CysArg: 0.999 ± 0.014
0.97CysSer: 0.97 ± 0.011
0.663CysThr: 0.663 ± 0.012
0.859CysVal: 0.859 ± 0.013
0.235CysTrp: 0.235 ± 0.006
0.338CysTyr: 0.338 ± 0.007
0.0CysXaa: 0.0 ± 0.0
Asp
5.599AspAla: 5.599 ± 0.034
0.665AspCys: 0.665 ± 0.012
4.829AspAsp: 4.829 ± 0.048
4.246AspGlu: 4.246 ± 0.037
1.987AspPhe: 1.987 ± 0.019
5.082AspGly: 5.082 ± 0.036
1.191AspHis: 1.191 ± 0.013
2.317AspIle: 2.317 ± 0.023
2.313AspLys: 2.313 ± 0.025
4.729AspLeu: 4.729 ± 0.025
1.319AspMet: 1.319 ± 0.014
1.6AspAsn: 1.6 ± 0.018
3.427AspPro: 3.427 ± 0.022
1.758AspGln: 1.758 ± 0.018
3.494AspArg: 3.494 ± 0.036
3.841AspSer: 3.841 ± 0.029
2.557AspThr: 2.557 ± 0.022
3.73AspVal: 3.73 ± 0.029
0.882AspTrp: 0.882 ± 0.011
1.335AspTyr: 1.335 ± 0.017
0.0AspXaa: 0.0 ± 0.0
Glu
6.036GluAla: 6.036 ± 0.046
0.632GluCys: 0.632 ± 0.012
3.724GluAsp: 3.724 ± 0.036
4.534GluGlu: 4.534 ± 0.047
1.659GluPhe: 1.659 ± 0.016
3.854GluGly: 3.854 ± 0.029
1.281GluHis: 1.281 ± 0.014
2.283GluIle: 2.283 ± 0.022
2.898GluLys: 2.898 ± 0.03
4.922GluLeu: 4.922 ± 0.035
1.377GluMet: 1.377 ± 0.014
1.673GluAsn: 1.673 ± 0.019
2.991GluPro: 2.991 ± 0.032
2.221GluGln: 2.221 ± 0.024
4.087GluArg: 4.087 ± 0.035
3.651GluSer: 3.651 ± 0.03
2.983GluThr: 2.983 ± 0.026
3.375GluVal: 3.375 ± 0.027
0.804GluTrp: 0.804 ± 0.012
1.322GluTyr: 1.322 ± 0.017
0.0GluXaa: 0.0 ± 0.0
Phe
3.135PheAla: 3.135 ± 0.022
0.55PheCys: 0.55 ± 0.008
2.053PheAsp: 2.053 ± 0.019
1.861PheGlu: 1.861 ± 0.017
1.466PhePhe: 1.466 ± 0.019
2.807PheGly: 2.807 ± 0.029
0.756PheHis: 0.756 ± 0.011
1.355PheIle: 1.355 ± 0.018
1.345PheLys: 1.345 ± 0.018
3.128PheLeu: 3.128 ± 0.028
0.682PheMet: 0.682 ± 0.012
1.162PheAsn: 1.162 ± 0.014
1.861PhePro: 1.861 ± 0.017
1.142PheGln: 1.142 ± 0.017
2.009PheArg: 2.009 ± 0.021
2.633PheSer: 2.633 ± 0.022
1.786PheThr: 1.786 ± 0.018
2.357PheVal: 2.357 ± 0.021
0.602PheTrp: 0.602 ± 0.009
0.916PheTyr: 0.916 ± 0.013
0.0PheXaa: 0.0 ± 0.0
Gly
7.554GlyAla: 7.554 ± 0.041
1.057GlyCys: 1.057 ± 0.014
4.435GlyAsp: 4.435 ± 0.032
3.81GlyGlu: 3.81 ± 0.026
2.758GlyPhe: 2.758 ± 0.025
9.487GlyGly: 9.487 ± 0.084
1.915GlyHis: 1.915 ± 0.021
3.042GlyIle: 3.042 ± 0.027
3.292GlyLys: 3.292 ± 0.027
6.421GlyLeu: 6.421 ± 0.04
1.699GlyMet: 1.699 ± 0.019
2.541GlyAsn: 2.541 ± 0.026
4.424GlyPro: 4.424 ± 0.035
2.831GlyGln: 2.831 ± 0.028
5.66GlyArg: 5.66 ± 0.035
6.712GlySer: 6.712 ± 0.043
4.162GlyThr: 4.162 ± 0.031
4.877GlyVal: 4.877 ± 0.033
1.286GlyTrp: 1.286 ± 0.017
1.908GlyTyr: 1.908 ± 0.017
0.0GlyXaa: 0.0 ± 0.0
His
2.077HisAla: 2.077 ± 0.021
0.331HisCys: 0.331 ± 0.008
1.317HisAsp: 1.317 ± 0.016
1.224HisGlu: 1.224 ± 0.015
0.81HisPhe: 0.81 ± 0.013
1.948HisGly: 1.948 ± 0.019
1.088HisHis: 1.088 ± 0.023
0.995HisIle: 0.995 ± 0.015
0.845HisLys: 0.845 ± 0.012
2.105HisLeu: 2.105 ± 0.021
0.534HisMet: 0.534 ± 0.01
0.712HisAsn: 0.712 ± 0.013
1.731HisPro: 1.731 ± 0.019
1.104HisGln: 1.104 ± 0.02
1.723HisArg: 1.723 ± 0.018
1.672HisSer: 1.672 ± 0.018
1.166HisThr: 1.166 ± 0.013
1.496HisVal: 1.496 ± 0.015
0.336HisTrp: 0.336 ± 0.007
0.615HisTyr: 0.615 ± 0.009
0.0HisXaa: 0.0 ± 0.0
Ile
3.543IleAla: 3.543 ± 0.024
0.658IleCys: 0.658 ± 0.011
2.205IleAsp: 2.205 ± 0.019
2.157IleGlu: 2.157 ± 0.022
1.519IlePhe: 1.519 ± 0.016
2.612IleGly: 2.612 ± 0.022
0.957IleHis: 0.957 ± 0.012
1.793IleIle: 1.793 ± 0.021
1.808IleLys: 1.808 ± 0.022
3.527IleLeu: 3.527 ± 0.026
0.902IleMet: 0.902 ± 0.013
1.373IleAsn: 1.373 ± 0.016
2.479IlePro: 2.479 ± 0.02
1.418IleGln: 1.418 ± 0.016
2.489IleArg: 2.489 ± 0.024
3.008IleSer: 3.008 ± 0.02
2.222IleThr: 2.222 ± 0.02
2.592IleVal: 2.592 ± 0.022
0.595IleTrp: 0.595 ± 0.009
1.051IleTyr: 1.051 ± 0.015
0.0IleXaa: 0.0 ± 0.0
Lys
4.28LysAla: 4.28 ± 0.039
0.475LysCys: 0.475 ± 0.009
2.38LysAsp: 2.38 ± 0.025
2.695LysGlu: 2.695 ± 0.03
1.241LysPhe: 1.241 ± 0.017
2.894LysGly: 2.894 ± 0.023
0.974LysHis: 0.974 ± 0.012
1.729LysIle: 1.729 ± 0.02
2.898LysLys: 2.898 ± 0.043
3.542LysLeu: 3.542 ± 0.031
0.92LysMet: 0.92 ± 0.011
1.366LysAsn: 1.366 ± 0.016
2.634LysPro: 2.634 ± 0.027
1.598LysGln: 1.598 ± 0.019
3.229LysArg: 3.229 ± 0.027
2.866LysSer: 2.866 ± 0.026
2.481LysThr: 2.481 ± 0.024
2.436LysVal: 2.436 ± 0.024
0.549LysTrp: 0.549 ± 0.01
1.035LysTyr: 1.035 ± 0.014
0.0LysXaa: 0.0 ± 0.0
Leu
9.238LeuAla: 9.238 ± 0.042
1.243LeuCys: 1.243 ± 0.016
5.093LeuAsp: 5.093 ± 0.03
5.09LeuGlu: 5.09 ± 0.038
2.969LeuPhe: 2.969 ± 0.025
6.485LeuGly: 6.485 ± 0.037
2.059LeuHis: 2.059 ± 0.021
3.024LeuIle: 3.024 ± 0.023
3.51LeuLys: 3.51 ± 0.033
8.367LeuLeu: 8.367 ± 0.06
1.678LeuMet: 1.678 ± 0.018
2.535LeuAsn: 2.535 ± 0.024
5.714LeuPro: 5.714 ± 0.038
3.387LeuGln: 3.387 ± 0.024
6.183LeuArg: 6.183 ± 0.041
6.608LeuSer: 6.608 ± 0.038
4.21LeuThr: 4.21 ± 0.028
5.772LeuVal: 5.772 ± 0.04
1.224LeuTrp: 1.224 ± 0.016
2.012LeuTyr: 2.012 ± 0.019
0.0LeuXaa: 0.0 ± 0.0
Met
2.624MetAla: 2.624 ± 0.021
0.25MetCys: 0.25 ± 0.007
1.252MetAsp: 1.252 ± 0.015
1.191MetGlu: 1.191 ± 0.015
0.68MetPhe: 0.68 ± 0.011
1.599MetGly: 1.599 ± 0.019
0.501MetHis: 0.501 ± 0.01
0.761MetIle: 0.761 ± 0.011
0.76MetLys: 0.76 ± 0.01
1.867MetLeu: 1.867 ± 0.019
0.57MetMet: 0.57 ± 0.01
0.605MetAsn: 0.605 ± 0.01
1.428MetPro: 1.428 ± 0.017
0.832MetGln: 0.832 ± 0.013
1.427MetArg: 1.427 ± 0.015
1.779MetSer: 1.779 ± 0.016
1.178MetThr: 1.178 ± 0.015
1.349MetVal: 1.349 ± 0.018
0.274MetTrp: 0.274 ± 0.007
0.474MetTyr: 0.474 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
2.754AsnAla: 2.754 ± 0.022
0.411AsnCys: 0.411 ± 0.009
1.614AsnAsp: 1.614 ± 0.017
1.473AsnGlu: 1.473 ± 0.014
1.11AsnPhe: 1.11 ± 0.013
2.854AsnGly: 2.854 ± 0.028
0.735AsnHis: 0.735 ± 0.011
1.463AsnIle: 1.463 ± 0.016
1.362AsnLys: 1.362 ± 0.018
2.632AsnLeu: 2.632 ± 0.026
0.761AsnMet: 0.761 ± 0.01
1.347AsnAsn: 1.347 ± 0.023
2.189AsnPro: 2.189 ± 0.022
1.064AsnGln: 1.064 ± 0.015
1.815AsnArg: 1.815 ± 0.017
2.278AsnSer: 2.278 ± 0.022
1.706AsnThr: 1.706 ± 0.019
1.948AsnVal: 1.948 ± 0.021
0.455AsnTrp: 0.455 ± 0.01
0.812AsnTyr: 0.812 ± 0.014
0.0AsnXaa: 0.0 ± 0.0
Pro
7.49ProAla: 7.49 ± 0.057
0.655ProCys: 0.655 ± 0.01
3.53ProAsp: 3.53 ± 0.025
3.78ProGlu: 3.78 ± 0.033
1.985ProPhe: 1.985 ± 0.018
5.186ProGly: 5.186 ± 0.037
1.458ProHis: 1.458 ± 0.018
2.173ProIle: 2.173 ± 0.021
2.468ProLys: 2.468 ± 0.025
5.044ProLeu: 5.044 ± 0.03
1.162ProMet: 1.162 ± 0.015
1.928ProAsn: 1.928 ± 0.019
6.924ProPro: 6.924 ± 0.081
2.699ProGln: 2.699 ± 0.035
4.469ProArg: 4.469 ± 0.038
6.24ProSer: 6.24 ± 0.044
4.171ProThr: 4.171 ± 0.038
3.898ProVal: 3.898 ± 0.031
0.814ProTrp: 0.814 ± 0.013
1.338ProTyr: 1.338 ± 0.017
0.0ProXaa: 0.0 ± 0.0
Gln
3.813GlnAla: 3.813 ± 0.033
0.432GlnCys: 0.432 ± 0.01
1.92GlnAsp: 1.92 ± 0.02
2.047GlnGlu: 2.047 ± 0.02
1.071GlnPhe: 1.071 ± 0.013
2.677GlnGly: 2.677 ± 0.028
1.199GlnHis: 1.199 ± 0.019
1.427GlnIle: 1.427 ± 0.015
1.567GlnLys: 1.567 ± 0.02
3.292GlnLeu: 3.292 ± 0.025
0.846GlnMet: 0.846 ± 0.012
1.209GlnAsn: 1.209 ± 0.017
2.94GlnPro: 2.94 ± 0.036
3.613GlnGln: 3.613 ± 0.087
2.79GlnArg: 2.79 ± 0.023
2.676GlnSer: 2.676 ± 0.025
2.067GlnThr: 2.067 ± 0.021
2.083GlnVal: 2.083 ± 0.02
0.525GlnTrp: 0.525 ± 0.008
0.945GlnTyr: 0.945 ± 0.013
0.0GlnXaa: 0.0 ± 0.0
Arg
6.449ArgAla: 6.449 ± 0.042
0.933ArgCys: 0.933 ± 0.014
3.982ArgAsp: 3.982 ± 0.04
4.002ArgGlu: 4.002 ± 0.038
2.29ArgPhe: 2.29 ± 0.021
4.996ArgGly: 4.996 ± 0.035
1.931ArgHis: 1.931 ± 0.02
2.622ArgIle: 2.622 ± 0.023
3.171ArgLys: 3.171 ± 0.028
6.301ArgLeu: 6.301 ± 0.039
1.412ArgMet: 1.412 ± 0.015
2.109ArgAsn: 2.109 ± 0.019
4.645ArgPro: 4.645 ± 0.036
2.95ArgGln: 2.95 ± 0.025
6.854ArgArg: 6.854 ± 0.053
5.165ArgSer: 5.165 ± 0.042
3.45ArgThr: 3.45 ± 0.025
3.881ArgVal: 3.881 ± 0.026
1.115ArgTrp: 1.115 ± 0.013
1.624ArgTyr: 1.624 ± 0.017
0.0ArgXaa: 0.0 ± 0.0
Ser
7.569SerAla: 7.569 ± 0.043
0.936SerCys: 0.936 ± 0.013
3.891SerAsp: 3.891 ± 0.031
3.463SerGlu: 3.463 ± 0.027
2.662SerPhe: 2.662 ± 0.023
6.307SerGly: 6.307 ± 0.041
1.84SerHis: 1.84 ± 0.018
3.124SerIle: 3.124 ± 0.026
3.038SerLys: 3.038 ± 0.026
6.679SerLeu: 6.679 ± 0.033
1.643SerMet: 1.643 ± 0.02
2.389SerAsn: 2.389 ± 0.023
6.09SerPro: 6.09 ± 0.057
2.886SerGln: 2.886 ± 0.027
5.578SerArg: 5.578 ± 0.043
8.734SerSer: 8.734 ± 0.076
4.951SerThr: 4.951 ± 0.042
4.423SerVal: 4.423 ± 0.03
1.123SerTrp: 1.123 ± 0.014
1.722SerTyr: 1.722 ± 0.018
0.0SerXaa: 0.0 ± 0.0
Thr
6.029ThrAla: 6.029 ± 0.04
0.753ThrCys: 0.753 ± 0.014
2.524ThrAsp: 2.524 ± 0.025
2.626ThrGlu: 2.626 ± 0.027
1.893ThrPhe: 1.893 ± 0.019
4.224ThrGly: 4.224 ± 0.031
1.161ThrHis: 1.161 ± 0.013
2.368ThrIle: 2.368 ± 0.024
2.206ThrLys: 2.206 ± 0.023
4.629ThrLeu: 4.629 ± 0.032
1.135ThrMet: 1.135 ± 0.015
1.684ThrAsn: 1.684 ± 0.02
4.492ThrPro: 4.492 ± 0.038
1.803ThrGln: 1.803 ± 0.02
3.378ThrArg: 3.378 ± 0.026
4.748ThrSer: 4.748 ± 0.039
4.25ThrThr: 4.25 ± 0.05
3.606ThrVal: 3.606 ± 0.032
0.809ThrTrp: 0.809 ± 0.012
1.307ThrTyr: 1.307 ± 0.014
0.0ThrXaa: 0.0 ± 0.0
Val
6.711ValAla: 6.711 ± 0.041
0.926ValCys: 0.926 ± 0.012
3.782ValAsp: 3.782 ± 0.023
3.671ValGlu: 3.671 ± 0.026
2.379ValPhe: 2.379 ± 0.022
4.528ValGly: 4.528 ± 0.031
1.36ValHis: 1.36 ± 0.016
2.386ValIle: 2.386 ± 0.021
2.577ValLys: 2.577 ± 0.025
5.723ValLeu: 5.723 ± 0.039
1.345ValMet: 1.345 ± 0.014
1.892ValAsn: 1.892 ± 0.019
3.973ValPro: 3.973 ± 0.029
2.162ValGln: 2.162 ± 0.018
4.063ValArg: 4.063 ± 0.029
4.481ValSer: 4.481 ± 0.033
3.373ValThr: 3.373 ± 0.032
4.903ValVal: 4.903 ± 0.035
0.938ValTrp: 0.938 ± 0.014
1.552ValTyr: 1.552 ± 0.017
0.0ValXaa: 0.0 ± 0.0
Trp
1.348TrpAla: 1.348 ± 0.017
0.227TrpCys: 0.227 ± 0.006
0.938TrpAsp: 0.938 ± 0.012
0.816TrpGlu: 0.816 ± 0.01
0.503TrpPhe: 0.503 ± 0.009
1.021TrpGly: 1.021 ± 0.014
0.374TrpHis: 0.374 ± 0.008
0.628TrpIle: 0.628 ± 0.01
0.635TrpLys: 0.635 ± 0.01
1.37TrpLeu: 1.37 ± 0.017
0.348TrpMet: 0.348 ± 0.008
0.534TrpAsn: 0.534 ± 0.008
0.729TrpPro: 0.729 ± 0.012
0.55TrpGln: 0.55 ± 0.01
1.148TrpArg: 1.148 ± 0.014
1.004TrpSer: 1.004 ± 0.013
0.856TrpThr: 0.856 ± 0.013
0.931TrpVal: 0.931 ± 0.013
0.29TrpTrp: 0.29 ± 0.008
0.364TrpTyr: 0.364 ± 0.007
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.973TyrAla: 1.973 ± 0.02
0.387TyrCys: 0.387 ± 0.009
1.411TyrAsp: 1.411 ± 0.015
1.251TyrGlu: 1.251 ± 0.016
0.967TyrPhe: 0.967 ± 0.013
1.94TyrGly: 1.94 ± 0.02
0.653TyrHis: 0.653 ± 0.011
1.023TyrIle: 1.023 ± 0.014
0.907TyrLys: 0.907 ± 0.013
2.166TyrLeu: 2.166 ± 0.024
0.558TyrMet: 0.558 ± 0.01
0.855TyrAsn: 0.855 ± 0.013
1.307TyrPro: 1.307 ± 0.017
0.922TyrGln: 0.922 ± 0.012
1.573TyrArg: 1.573 ± 0.017
1.702TyrSer: 1.702 ± 0.017
1.267TyrThr: 1.267 ± 0.016
1.452TyrVal: 1.452 ± 0.015
0.395TyrTrp: 0.395 ± 0.009
0.786TyrTyr: 0.786 ± 0.011
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 14597 proteins (6286680 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski