Amino acid dipepetide frequency for Saccharicrinis carchari

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.837AlaAla: 4.837 ± 0.082	0.715AlaCys: 0.715 ± 0.024	3.747AlaAsp: 3.747 ± 0.062	3.983AlaGlu: 3.983 ± 0.063	3.272AlaPhe: 3.272 ± 0.046	4.89AlaGly: 4.89 ± 0.078	1.402AlaHis: 1.402 ± 0.037	5.226AlaIle: 5.226 ± 0.078	4.442AlaLys: 4.442 ± 0.074	6.639AlaLeu: 6.639 ± 0.082	1.8AlaMet: 1.8 ± 0.043	3.454AlaAsn: 3.454 ± 0.053	2.125AlaPro: 2.125 ± 0.042	2.909AlaGln: 2.909 ± 0.05	2.646AlaArg: 2.646 ± 0.054	4.325AlaSer: 4.325 ± 0.069	3.612AlaThr: 3.612 ± 0.074	4.293AlaVal: 4.293 ± 0.065	0.776AlaTrp: 0.776 ± 0.029	2.826AlaTyr: 2.826 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.555CysAla: 0.555 ± 0.024	0.091CysCys: 0.091 ± 0.009	0.47CysAsp: 0.47 ± 0.019	0.482CysGlu: 0.482 ± 0.025	0.393CysPhe: 0.393 ± 0.018	0.648CysGly: 0.648 ± 0.026	0.232CysHis: 0.232 ± 0.019	0.617CysIle: 0.617 ± 0.022	0.526CysLys: 0.526 ± 0.024	0.674CysLeu: 0.674 ± 0.022	0.184CysMet: 0.184 ± 0.011	0.475CysAsn: 0.475 ± 0.02	0.376CysPro: 0.376 ± 0.02	0.284CysGln: 0.284 ± 0.015	0.316CysArg: 0.316 ± 0.017	0.566CysSer: 0.566 ± 0.026	0.461CysThr: 0.461 ± 0.021	0.522CysVal: 0.522 ± 0.024	0.095CysTrp: 0.095 ± 0.009	0.34CysTyr: 0.34 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.754AspAla: 3.754 ± 0.06	0.43AspCys: 0.43 ± 0.018	2.806AspAsp: 2.806 ± 0.045	3.624AspGlu: 3.624 ± 0.063	3.288AspPhe: 3.288 ± 0.055	3.863AspGly: 3.863 ± 0.071	0.945AspHis: 0.945 ± 0.027	4.407AspIle: 4.407 ± 0.055	4.297AspLys: 4.297 ± 0.064	4.832AspLeu: 4.832 ± 0.067	1.481AspMet: 1.481 ± 0.036	3.025AspAsn: 3.025 ± 0.047	1.898AspPro: 1.898 ± 0.037	1.527AspGln: 1.527 ± 0.036	2.039AspArg: 2.039 ± 0.036	3.123AspSer: 3.123 ± 0.051	2.734AspThr: 2.734 ± 0.043	3.575AspVal: 3.575 ± 0.06	0.757AspTrp: 0.757 ± 0.026	2.658AspTyr: 2.658 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	4.259GluAla: 4.259 ± 0.074	0.422GluCys: 0.422 ± 0.019	3.159GluAsp: 3.159 ± 0.049	4.332GluGlu: 4.332 ± 0.074	2.619GluPhe: 2.619 ± 0.048	3.798GluGly: 3.798 ± 0.056	1.145GluHis: 1.145 ± 0.034	4.713GluIle: 4.713 ± 0.07	5.103GluLys: 5.103 ± 0.076	6.239GluLeu: 6.239 ± 0.076	1.772GluMet: 1.772 ± 0.042	3.527GluAsn: 3.527 ± 0.049	1.728GluPro: 1.728 ± 0.042	2.401GluGln: 2.401 ± 0.048	2.596GluArg: 2.596 ± 0.043	3.277GluSer: 3.277 ± 0.045	2.935GluThr: 2.935 ± 0.045	4.383GluVal: 4.383 ± 0.059	0.701GluTrp: 0.701 ± 0.022	2.382GluTyr: 2.382 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	3.052PheAla: 3.052 ± 0.053	0.447PheCys: 0.447 ± 0.018	3.027PheAsp: 3.027 ± 0.047	2.973PheGlu: 2.973 ± 0.044	2.521PhePhe: 2.521 ± 0.057	3.376PheGly: 3.376 ± 0.056	0.766PheHis: 0.766 ± 0.026	3.691PheIle: 3.691 ± 0.054	3.403PheLys: 3.403 ± 0.062	4.131PheLeu: 4.131 ± 0.084	1.266PheMet: 1.266 ± 0.03	3.037PheAsn: 3.037 ± 0.055	1.646PhePro: 1.646 ± 0.037	1.193PheGln: 1.193 ± 0.029	1.733PheArg: 1.733 ± 0.043	3.698PheSer: 3.698 ± 0.052	2.957PheThr: 2.957 ± 0.051	3.26PheVal: 3.26 ± 0.043	0.596PheTrp: 0.596 ± 0.025	2.147PheTyr: 2.147 ± 0.05	0.0PheXaa: 0.0 ± 0.0
Gly	4.73GlyAla: 4.73 ± 0.08	0.647GlyCys: 0.647 ± 0.034	3.569GlyAsp: 3.569 ± 0.063	3.912GlyGlu: 3.912 ± 0.058	3.589GlyPhe: 3.589 ± 0.06	4.88GlyGly: 4.88 ± 0.09	1.283GlyHis: 1.283 ± 0.033	5.557GlyIle: 5.557 ± 0.071	4.985GlyLys: 4.985 ± 0.063	6.156GlyLeu: 6.156 ± 0.074	1.95GlyMet: 1.95 ± 0.04	3.714GlyAsn: 3.714 ± 0.069	1.44GlyPro: 1.44 ± 0.034	2.191GlyGln: 2.191 ± 0.046	2.533GlyArg: 2.533 ± 0.048	4.275GlySer: 4.275 ± 0.086	3.97GlyThr: 3.97 ± 0.104	4.73GlyVal: 4.73 ± 0.074	0.865GlyTrp: 0.865 ± 0.029	2.95GlyTyr: 2.95 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.179HisAla: 1.179 ± 0.032	0.207HisCys: 0.207 ± 0.013	0.902HisAsp: 0.902 ± 0.023	0.999HisGlu: 0.999 ± 0.03	1.16HisPhe: 1.16 ± 0.032	1.202HisGly: 1.202 ± 0.031	0.592HisHis: 0.592 ± 0.026	1.572HisIle: 1.572 ± 0.029	1.331HisLys: 1.331 ± 0.037	2.019HisLeu: 2.019 ± 0.039	0.411HisMet: 0.411 ± 0.021	1.07HisAsn: 1.07 ± 0.031	1.042HisPro: 1.042 ± 0.032	0.821HisGln: 0.821 ± 0.026	0.839HisArg: 0.839 ± 0.025	1.21HisSer: 1.21 ± 0.034	1.071HisThr: 1.071 ± 0.029	1.052HisVal: 1.052 ± 0.026	0.261HisTrp: 0.261 ± 0.013	0.895HisTyr: 0.895 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.34IleAla: 5.34 ± 0.068	0.633IleCys: 0.633 ± 0.022	4.669IleAsp: 4.669 ± 0.06	5.044IleGlu: 5.044 ± 0.068	3.206IlePhe: 3.206 ± 0.056	4.888IleGly: 4.888 ± 0.064	1.468IleHis: 1.468 ± 0.034	5.256IleIle: 5.256 ± 0.085	5.59IleLys: 5.59 ± 0.083	6.344IleLeu: 6.344 ± 0.079	1.481IleMet: 1.481 ± 0.035	4.535IleAsn: 4.535 ± 0.064	3.137IlePro: 3.137 ± 0.055	2.393IleGln: 2.393 ± 0.049	2.936IleArg: 2.936 ± 0.043	5.402IleSer: 5.402 ± 0.065	4.25IleThr: 4.25 ± 0.075	4.709IleVal: 4.709 ± 0.061	0.798IleTrp: 0.798 ± 0.028	2.784IleTyr: 2.784 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	5.044LysAla: 5.044 ± 0.079	0.412LysCys: 0.412 ± 0.019	3.976LysAsp: 3.976 ± 0.055	5.428LysGlu: 5.428 ± 0.084	2.421LysPhe: 2.421 ± 0.05	4.754LysGly: 4.754 ± 0.071	1.449LysHis: 1.449 ± 0.036	5.354LysIle: 5.354 ± 0.073	6.015LysLys: 6.015 ± 0.082	6.223LysLeu: 6.223 ± 0.091	2.147LysMet: 2.147 ± 0.046	4.471LysAsn: 4.471 ± 0.066	2.482LysPro: 2.482 ± 0.043	2.884LysGln: 2.884 ± 0.047	2.898LysArg: 2.898 ± 0.057	4.064LysSer: 4.064 ± 0.058	4.055LysThr: 4.055 ± 0.057	4.85LysVal: 4.85 ± 0.068	0.77LysTrp: 0.77 ± 0.028	3.026LysTyr: 3.026 ± 0.051	0.0LysXaa: 0.0 ± 0.0
Leu	6.242LeuAla: 6.242 ± 0.074	0.788LeuCys: 0.788 ± 0.026	4.652LeuAsp: 4.652 ± 0.056	5.045LeuGlu: 5.045 ± 0.064	4.763LeuPhe: 4.763 ± 0.079	5.728LeuGly: 5.728 ± 0.078	1.775LeuHis: 1.775 ± 0.034	6.722LeuIle: 6.722 ± 0.088	7.44LeuLys: 7.44 ± 0.085	9.315LeuLeu: 9.315 ± 0.13	2.468LeuMet: 2.468 ± 0.048	5.721LeuAsn: 5.721 ± 0.071	3.863LeuPro: 3.863 ± 0.056	3.375LeuGln: 3.375 ± 0.051	3.515LeuArg: 3.515 ± 0.058	7.254LeuSer: 7.254 ± 0.089	4.914LeuThr: 4.914 ± 0.073	5.413LeuVal: 5.413 ± 0.063	0.933LeuTrp: 0.933 ± 0.033	3.283LeuTyr: 3.283 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	2.169MetAla: 2.169 ± 0.047	0.155MetCys: 0.155 ± 0.011	1.531MetAsp: 1.531 ± 0.037	1.708MetGlu: 1.708 ± 0.039	0.937MetPhe: 0.937 ± 0.027	1.933MetGly: 1.933 ± 0.042	0.523MetHis: 0.523 ± 0.018	1.606MetIle: 1.606 ± 0.035	1.926MetLys: 1.926 ± 0.037	2.424MetLeu: 2.424 ± 0.046	0.655MetMet: 0.655 ± 0.028	1.3MetAsn: 1.3 ± 0.035	1.149MetPro: 1.149 ± 0.028	0.951MetGln: 0.951 ± 0.024	1.034MetArg: 1.034 ± 0.027	1.492MetSer: 1.492 ± 0.032	1.098MetThr: 1.098 ± 0.032	1.845MetVal: 1.845 ± 0.041	0.198MetTrp: 0.198 ± 0.012	0.801MetTyr: 0.801 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.671AsnAla: 3.671 ± 0.062	0.454AsnCys: 0.454 ± 0.026	2.971AsnAsp: 2.971 ± 0.05	3.228AsnGlu: 3.228 ± 0.046	2.529AsnPhe: 2.529 ± 0.046	3.887AsnGly: 3.887 ± 0.087	1.086AsnHis: 1.086 ± 0.026	4.656AsnIle: 4.656 ± 0.062	4.475AsnLys: 4.475 ± 0.062	4.955AsnLeu: 4.955 ± 0.07	1.43AsnMet: 1.43 ± 0.036	3.542AsnAsn: 3.542 ± 0.079	2.679AsnPro: 2.679 ± 0.051	2.122AsnGln: 2.122 ± 0.039	2.366AsnArg: 2.366 ± 0.048	3.355AsnSer: 3.355 ± 0.057	3.27AsnThr: 3.27 ± 0.056	3.186AsnVal: 3.186 ± 0.06	0.765AsnTrp: 0.765 ± 0.029	2.67AsnTyr: 2.67 ± 0.053	0.0AsnXaa: 0.0 ± 0.0
Pro	2.461ProAla: 2.461 ± 0.06	0.258ProCys: 0.258 ± 0.013	2.456ProAsp: 2.456 ± 0.053	2.723ProGlu: 2.723 ± 0.045	1.874ProPhe: 1.874 ± 0.04	2.578ProGly: 2.578 ± 0.048	0.82ProHis: 0.82 ± 0.023	2.532ProIle: 2.532 ± 0.039	2.081ProLys: 2.081 ± 0.046	3.275ProLeu: 3.275 ± 0.051	0.813ProMet: 0.813 ± 0.025	1.969ProAsn: 1.969 ± 0.04	0.998ProPro: 0.998 ± 0.031	1.425ProGln: 1.425 ± 0.031	1.15ProArg: 1.15 ± 0.029	2.141ProSer: 2.141 ± 0.041	1.857ProThr: 1.857 ± 0.04	2.864ProVal: 2.864 ± 0.048	0.406ProTrp: 0.406 ± 0.02	1.536ProTyr: 1.536 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.366GlnAla: 2.366 ± 0.045	0.235GlnCys: 0.235 ± 0.016	1.533GlnAsp: 1.533 ± 0.032	2.174GlnGlu: 2.174 ± 0.044	1.566GlnPhe: 1.566 ± 0.035	2.153GlnGly: 2.153 ± 0.04	0.766GlnHis: 0.766 ± 0.022	2.71GlnIle: 2.71 ± 0.046	2.929GlnLys: 2.929 ± 0.05	3.802GlnLeu: 3.802 ± 0.058	0.995GlnMet: 0.995 ± 0.034	2.092GlnAsn: 2.092 ± 0.042	1.138GlnPro: 1.138 ± 0.03	1.693GlnGln: 1.693 ± 0.035	1.482GlnArg: 1.482 ± 0.036	2.21GlnSer: 2.21 ± 0.042	1.894GlnThr: 1.894 ± 0.043	2.282GlnVal: 2.282 ± 0.049	0.467GlnTrp: 0.467 ± 0.02	1.39GlnTyr: 1.39 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.363ArgAla: 2.363 ± 0.052	0.294ArgCys: 0.294 ± 0.015	1.982ArgAsp: 1.982 ± 0.044	2.488ArgGlu: 2.488 ± 0.048	2.11ArgPhe: 2.11 ± 0.04	2.205ArgGly: 2.205 ± 0.05	0.756ArgHis: 0.756 ± 0.028	3.211ArgIle: 3.211 ± 0.045	2.92ArgLys: 2.92 ± 0.052	3.746ArgLeu: 3.746 ± 0.061	1.174ArgMet: 1.174 ± 0.033	2.299ArgAsn: 2.299 ± 0.043	1.299ArgPro: 1.299 ± 0.034	1.395ArgGln: 1.395 ± 0.038	1.577ArgArg: 1.577 ± 0.039	2.164ArgSer: 2.164 ± 0.045	1.906ArgThr: 1.906 ± 0.04	2.494ArgVal: 2.494 ± 0.042	0.506ArgTrp: 0.506 ± 0.021	1.849ArgTyr: 1.849 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	4.266SerAla: 4.266 ± 0.057	0.619SerCys: 0.619 ± 0.022	3.65SerAsp: 3.65 ± 0.05	3.63SerGlu: 3.63 ± 0.062	3.658SerPhe: 3.658 ± 0.054	5.09SerGly: 5.09 ± 0.1	1.294SerHis: 1.294 ± 0.032	4.889SerIle: 4.889 ± 0.069	4.015SerLys: 4.015 ± 0.06	6.023SerLeu: 6.023 ± 0.075	1.48SerMet: 1.48 ± 0.032	3.443SerAsn: 3.443 ± 0.069	2.383SerPro: 2.383 ± 0.048	2.068SerGln: 2.068 ± 0.038	2.377SerArg: 2.377 ± 0.048	4.174SerSer: 4.174 ± 0.082	3.439SerThr: 3.439 ± 0.061	4.312SerVal: 4.312 ± 0.063	0.712SerTrp: 0.712 ± 0.024	2.757SerTyr: 2.757 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	3.737ThrAla: 3.737 ± 0.067	0.421ThrCys: 0.421 ± 0.02	3.201ThrAsp: 3.201 ± 0.059	3.015ThrGlu: 3.015 ± 0.046	2.711ThrPhe: 2.711 ± 0.056	4.266ThrGly: 4.266 ± 0.08	1.125ThrHis: 1.125 ± 0.028	4.218ThrIle: 4.218 ± 0.076	3.04ThrLys: 3.04 ± 0.052	5.089ThrLeu: 5.089 ± 0.08	1.122ThrMet: 1.122 ± 0.033	2.683ThrAsn: 2.683 ± 0.057	2.366ThrPro: 2.366 ± 0.051	1.871ThrGln: 1.871 ± 0.038	1.853ThrArg: 1.853 ± 0.036	3.28ThrSer: 3.28 ± 0.06	2.899ThrThr: 2.899 ± 0.062	3.855ThrVal: 3.855 ± 0.102	0.636ThrTrp: 0.636 ± 0.024	2.168ThrTyr: 2.168 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	4.504ValAla: 4.504 ± 0.064	0.584ValCys: 0.584 ± 0.03	3.72ValAsp: 3.72 ± 0.053	3.992ValGlu: 3.992 ± 0.054	3.423ValPhe: 3.423 ± 0.062	4.09ValGly: 4.09 ± 0.065	1.218ValHis: 1.218 ± 0.032	4.528ValIle: 4.528 ± 0.06	4.592ValLys: 4.592 ± 0.057	6.245ValLeu: 6.245 ± 0.087	1.578ValMet: 1.578 ± 0.037	3.729ValAsn: 3.729 ± 0.06	2.471ValPro: 2.471 ± 0.044	2.16ValGln: 2.16 ± 0.04	2.474ValArg: 2.474 ± 0.048	4.691ValSer: 4.691 ± 0.066	3.26ValThr: 3.26 ± 0.076	4.715ValVal: 4.715 ± 0.073	0.718ValTrp: 0.718 ± 0.025	2.581ValTyr: 2.581 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.735TrpAla: 0.735 ± 0.027	0.105TrpCys: 0.105 ± 0.009	0.748TrpAsp: 0.748 ± 0.028	0.722TrpGlu: 0.722 ± 0.024	0.546TrpPhe: 0.546 ± 0.024	0.89TrpGly: 0.89 ± 0.032	0.264TrpHis: 0.264 ± 0.016	0.752TrpIle: 0.752 ± 0.026	0.716TrpLys: 0.716 ± 0.025	1.136TrpLeu: 1.136 ± 0.033	0.342TrpMet: 0.342 ± 0.016	0.691TrpAsn: 0.691 ± 0.026	0.316TrpPro: 0.316 ± 0.018	0.497TrpGln: 0.497 ± 0.023	0.502TrpArg: 0.502 ± 0.02	0.741TrpSer: 0.741 ± 0.026	0.603TrpThr: 0.603 ± 0.027	0.74TrpVal: 0.74 ± 0.023	0.17TrpTrp: 0.17 ± 0.013	0.445TrpTyr: 0.445 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.651TyrAla: 2.651 ± 0.046	0.394TyrCys: 0.394 ± 0.02	2.293TyrAsp: 2.293 ± 0.046	1.99TyrGlu: 1.99 ± 0.041	2.334TyrPhe: 2.334 ± 0.051	2.806TyrGly: 2.806 ± 0.05	0.926TyrHis: 0.926 ± 0.029	2.648TyrIle: 2.648 ± 0.043	2.894TyrLys: 2.894 ± 0.05	3.939TyrLeu: 3.939 ± 0.058	0.886TyrMet: 0.886 ± 0.027	2.52TyrAsn: 2.52 ± 0.057	1.681TyrPro: 1.681 ± 0.037	1.72TyrGln: 1.72 ± 0.042	1.87TyrArg: 1.87 ± 0.034	2.838TyrSer: 2.838 ± 0.049	2.374TyrThr: 2.374 ± 0.055	2.193TyrVal: 2.193 ± 0.039	0.529TyrTrp: 0.529 ± 0.022	1.92TyrTyr: 1.92 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3615 proteins (1343413 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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