Amino acid dipepetide frequency for Arachidicoccus rhizosphaerae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.294AlaAla: 7.294 ± 0.094	0.616AlaCys: 0.616 ± 0.024	4.335AlaAsp: 4.335 ± 0.064	3.965AlaGlu: 3.965 ± 0.068	3.511AlaPhe: 3.511 ± 0.054	6.083AlaGly: 6.083 ± 0.064	1.359AlaHis: 1.359 ± 0.032	5.346AlaIle: 5.346 ± 0.074	4.452AlaLys: 4.452 ± 0.066	7.435AlaLeu: 7.435 ± 0.085	1.754AlaMet: 1.754 ± 0.034	3.105AlaAsn: 3.105 ± 0.056	2.773AlaPro: 2.773 ± 0.056	2.879AlaGln: 2.879 ± 0.049	2.805AlaArg: 2.805 ± 0.048	5.035AlaSer: 5.035 ± 0.072	4.49AlaThr: 4.49 ± 0.062	4.816AlaVal: 4.816 ± 0.07	0.826AlaTrp: 0.826 ± 0.028	2.912AlaTyr: 2.912 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.462CysAla: 0.462 ± 0.021	0.144CysCys: 0.144 ± 0.011	0.357CysAsp: 0.357 ± 0.016	0.327CysGlu: 0.327 ± 0.017	0.455CysPhe: 0.455 ± 0.017	0.624CysGly: 0.624 ± 0.023	0.204CysHis: 0.204 ± 0.013	0.64CysIle: 0.64 ± 0.025	0.489CysLys: 0.489 ± 0.02	0.924CysLeu: 0.924 ± 0.032	0.228CysMet: 0.228 ± 0.012	0.378CysAsn: 0.378 ± 0.016	0.34CysPro: 0.34 ± 0.017	0.325CysGln: 0.325 ± 0.017	0.317CysArg: 0.317 ± 0.015	0.606CysSer: 0.606 ± 0.024	0.429CysThr: 0.429 ± 0.018	0.433CysVal: 0.433 ± 0.018	0.12CysTrp: 0.12 ± 0.009	0.344CysTyr: 0.344 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.859AspAla: 3.859 ± 0.052	0.397AspCys: 0.397 ± 0.017	2.329AspAsp: 2.329 ± 0.052	2.637AspGlu: 2.637 ± 0.048	3.149AspPhe: 3.149 ± 0.048	4.054AspGly: 4.054 ± 0.063	1.142AspHis: 1.142 ± 0.03	4.031AspIle: 4.031 ± 0.055	3.813AspLys: 3.813 ± 0.053	5.365AspLeu: 5.365 ± 0.069	1.196AspMet: 1.196 ± 0.03	2.913AspAsn: 2.913 ± 0.046	2.424AspPro: 2.424 ± 0.048	2.62AspGln: 2.62 ± 0.05	2.249AspArg: 2.249 ± 0.042	3.812AspSer: 3.812 ± 0.068	2.666AspThr: 2.666 ± 0.054	2.968AspVal: 2.968 ± 0.052	0.928AspTrp: 0.928 ± 0.023	2.872AspTyr: 2.872 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.355GluAla: 4.355 ± 0.071	0.293GluCys: 0.293 ± 0.017	2.848GluAsp: 2.848 ± 0.048	2.773GluGlu: 2.773 ± 0.066	1.96GluPhe: 1.96 ± 0.037	3.452GluGly: 3.452 ± 0.062	0.974GluHis: 0.974 ± 0.029	3.745GluIle: 3.745 ± 0.058	4.452GluLys: 4.452 ± 0.07	5.358GluLeu: 5.358 ± 0.071	1.345GluMet: 1.345 ± 0.034	3.15GluAsn: 3.15 ± 0.049	1.622GluPro: 1.622 ± 0.031	2.764GluGln: 2.764 ± 0.049	2.131GluArg: 2.131 ± 0.044	2.672GluSer: 2.672 ± 0.05	2.436GluThr: 2.436 ± 0.037	3.292GluVal: 3.292 ± 0.053	0.571GluTrp: 0.571 ± 0.021	1.676GluTyr: 1.676 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.034PheAla: 3.034 ± 0.048	0.46PheCys: 0.46 ± 0.019	2.814PheAsp: 2.814 ± 0.047	2.512PheGlu: 2.512 ± 0.048	2.191PhePhe: 2.191 ± 0.047	3.372PheGly: 3.372 ± 0.056	0.832PheHis: 0.832 ± 0.025	3.364PheIle: 3.364 ± 0.062	3.254PheLys: 3.254 ± 0.059	4.222PheLeu: 4.222 ± 0.065	1.156PheMet: 1.156 ± 0.028	2.855PheAsn: 2.855 ± 0.047	1.737PhePro: 1.737 ± 0.038	1.517PheGln: 1.517 ± 0.034	1.67PheArg: 1.67 ± 0.036	3.545PheSer: 3.545 ± 0.055	2.874PheThr: 2.874 ± 0.042	2.609PheVal: 2.609 ± 0.053	0.643PheTrp: 0.643 ± 0.021	2.112PheTyr: 2.112 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	5.215GlyAla: 5.215 ± 0.075	0.694GlyCys: 0.694 ± 0.024	3.645GlyAsp: 3.645 ± 0.056	3.078GlyGlu: 3.078 ± 0.056	3.594GlyPhe: 3.594 ± 0.057	5.137GlyGly: 5.137 ± 0.081	1.576GlyHis: 1.576 ± 0.034	5.285GlyIle: 5.285 ± 0.069	5.256GlyLys: 5.256 ± 0.07	6.847GlyLeu: 6.847 ± 0.062	1.749GlyMet: 1.749 ± 0.038	3.65GlyAsn: 3.65 ± 0.055	1.827GlyPro: 1.827 ± 0.04	3.036GlyGln: 3.036 ± 0.048	2.939GlyArg: 2.939 ± 0.044	4.993GlySer: 4.993 ± 0.075	4.075GlyThr: 4.075 ± 0.053	4.454GlyVal: 4.454 ± 0.064	1.223GlyTrp: 1.223 ± 0.03	3.504GlyTyr: 3.504 ± 0.061	0.0GlyXaa: 0.0 ± 0.0
His	1.181HisAla: 1.181 ± 0.034	0.206HisCys: 0.206 ± 0.013	0.874HisAsp: 0.874 ± 0.025	0.931HisGlu: 0.931 ± 0.025	1.258HisPhe: 1.258 ± 0.031	1.15HisGly: 1.15 ± 0.026	0.554HisHis: 0.554 ± 0.024	1.438HisIle: 1.438 ± 0.038	1.206HisLys: 1.206 ± 0.029	2.233HisLeu: 2.233 ± 0.043	0.47HisMet: 0.47 ± 0.019	1.022HisAsn: 1.022 ± 0.028	1.19HisPro: 1.19 ± 0.03	0.929HisGln: 0.929 ± 0.025	0.806HisArg: 0.806 ± 0.024	1.206HisSer: 1.206 ± 0.032	1.015HisThr: 1.015 ± 0.028	0.956HisVal: 0.956 ± 0.029	0.315HisTrp: 0.315 ± 0.015	1.105HisTyr: 1.105 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.21IleAla: 5.21 ± 0.073	0.752IleCys: 0.752 ± 0.024	4.037IleAsp: 4.037 ± 0.059	3.833IleGlu: 3.833 ± 0.06	2.997IlePhe: 2.997 ± 0.05	4.786IleGly: 4.786 ± 0.069	1.493IleHis: 1.493 ± 0.04	4.757IleIle: 4.757 ± 0.076	4.795IleLys: 4.795 ± 0.057	6.293IleLeu: 6.293 ± 0.084	1.338IleMet: 1.338 ± 0.034	3.693IleAsn: 3.693 ± 0.058	2.921IlePro: 2.921 ± 0.048	2.978IleGln: 2.978 ± 0.049	3.184IleArg: 3.184 ± 0.047	4.934IleSer: 4.934 ± 0.064	4.227IleThr: 4.227 ± 0.063	3.695IleVal: 3.695 ± 0.056	0.785IleTrp: 0.785 ± 0.026	2.802IleTyr: 2.802 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	5.369LysAla: 5.369 ± 0.078	0.337LysCys: 0.337 ± 0.016	4.507LysAsp: 4.507 ± 0.057	4.582LysGlu: 4.582 ± 0.066	2.216LysPhe: 2.216 ± 0.039	4.817LysGly: 4.817 ± 0.054	1.116LysHis: 1.116 ± 0.028	4.742LysIle: 4.742 ± 0.063	5.404LysLys: 5.404 ± 0.081	5.472LysLeu: 5.472 ± 0.069	1.825LysMet: 1.825 ± 0.04	3.926LysAsn: 3.926 ± 0.055	2.331LysPro: 2.331 ± 0.044	2.755LysGln: 2.755 ± 0.05	2.667LysArg: 2.667 ± 0.039	4.095LysSer: 4.095 ± 0.051	3.978LysThr: 3.978 ± 0.051	4.091LysVal: 4.091 ± 0.059	0.919LysTrp: 0.919 ± 0.026	2.682LysTyr: 2.682 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	6.784LeuAla: 6.784 ± 0.08	0.876LeuCys: 0.876 ± 0.026	5.192LeuAsp: 5.192 ± 0.064	5.019LeuGlu: 5.019 ± 0.077	4.573LeuPhe: 4.573 ± 0.064	6.318LeuGly: 6.318 ± 0.071	1.942LeuHis: 1.942 ± 0.037	6.542LeuIle: 6.542 ± 0.094	6.981LeuLys: 6.981 ± 0.079	9.627LeuLeu: 9.627 ± 0.105	2.388LeuMet: 2.388 ± 0.049	5.137LeuAsn: 5.137 ± 0.068	4.523LeuPro: 4.523 ± 0.06	4.107LeuGln: 4.107 ± 0.064	3.786LeuArg: 3.786 ± 0.054	7.402LeuSer: 7.402 ± 0.068	5.386LeuThr: 5.386 ± 0.059	5.03LeuVal: 5.03 ± 0.067	1.06LeuTrp: 1.06 ± 0.028	3.638LeuTyr: 3.638 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.092MetAla: 2.092 ± 0.043	0.128MetCys: 0.128 ± 0.008	1.491MetAsp: 1.491 ± 0.035	1.523MetGlu: 1.523 ± 0.037	0.769MetPhe: 0.769 ± 0.033	1.678MetGly: 1.678 ± 0.038	0.548MetHis: 0.548 ± 0.021	1.472MetIle: 1.472 ± 0.034	1.578MetLys: 1.578 ± 0.034	2.06MetLeu: 2.06 ± 0.038	0.67MetMet: 0.67 ± 0.025	1.132MetAsn: 1.132 ± 0.029	1.019MetPro: 1.019 ± 0.028	1.235MetGln: 1.235 ± 0.031	0.976MetArg: 0.976 ± 0.026	1.394MetSer: 1.394 ± 0.035	1.349MetThr: 1.349 ± 0.034	1.503MetVal: 1.503 ± 0.035	0.223MetTrp: 0.223 ± 0.014	0.673MetTyr: 0.673 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.583AsnAla: 3.583 ± 0.052	0.429AsnCys: 0.429 ± 0.02	2.551AsnAsp: 2.551 ± 0.043	2.439AsnGlu: 2.439 ± 0.042	2.348AsnPhe: 2.348 ± 0.046	4.034AsnGly: 4.034 ± 0.066	1.051AsnHis: 1.051 ± 0.028	3.698AsnIle: 3.698 ± 0.053	3.61AsnLys: 3.61 ± 0.047	4.696AsnLeu: 4.696 ± 0.06	1.147AsnMet: 1.147 ± 0.033	2.988AsnAsn: 2.988 ± 0.056	2.655AsnPro: 2.655 ± 0.044	2.325AsnGln: 2.325 ± 0.041	2.198AsnArg: 2.198 ± 0.038	3.201AsnSer: 3.201 ± 0.058	3.065AsnThr: 3.065 ± 0.054	2.666AsnVal: 2.666 ± 0.055	0.834AsnTrp: 0.834 ± 0.026	2.521AsnTyr: 2.521 ± 0.048	0.0AsnXaa: 0.0 ± 0.0
Pro	3.405ProAla: 3.405 ± 0.063	0.241ProCys: 0.241 ± 0.013	2.842ProAsp: 2.842 ± 0.042	2.892ProGlu: 2.892 ± 0.049	1.979ProPhe: 1.979 ± 0.044	3.212ProGly: 3.212 ± 0.056	0.729ProHis: 0.729 ± 0.023	2.298ProIle: 2.298 ± 0.04	2.263ProLys: 2.263 ± 0.045	3.596ProLeu: 3.596 ± 0.058	0.862ProMet: 0.862 ± 0.029	1.735ProAsn: 1.735 ± 0.038	1.062ProPro: 1.062 ± 0.032	1.41ProGln: 1.41 ± 0.033	1.251ProArg: 1.251 ± 0.029	2.431ProSer: 2.431 ± 0.047	2.09ProThr: 2.09 ± 0.035	3.24ProVal: 3.24 ± 0.054	0.513ProTrp: 0.513 ± 0.019	1.761ProTyr: 1.761 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.237GlnAla: 3.237 ± 0.059	0.198GlnCys: 0.198 ± 0.012	2.144GlnAsp: 2.144 ± 0.036	1.987GlnGlu: 1.987 ± 0.042	1.825GlnPhe: 1.825 ± 0.037	2.563GlnGly: 2.563 ± 0.044	0.897GlnHis: 0.897 ± 0.025	3.009GlnIle: 3.009 ± 0.045	3.201GlnLys: 3.201 ± 0.047	4.489GlnLeu: 4.489 ± 0.065	1.12GlnMet: 1.12 ± 0.028	2.235GlnAsn: 2.235 ± 0.047	1.796GlnPro: 1.796 ± 0.042	2.687GlnGln: 2.687 ± 0.057	1.674GlnArg: 1.674 ± 0.045	2.591GlnSer: 2.591 ± 0.043	2.403GlnThr: 2.403 ± 0.048	2.69GlnVal: 2.69 ± 0.039	0.526GlnTrp: 0.526 ± 0.02	1.752GlnTyr: 1.752 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.678ArgAla: 2.678 ± 0.048	0.272ArgCys: 0.272 ± 0.015	1.962ArgAsp: 1.962 ± 0.036	2.053ArgGlu: 2.053 ± 0.043	2.14ArgPhe: 2.14 ± 0.041	2.226ArgGly: 2.226 ± 0.045	0.84ArgHis: 0.84 ± 0.025	3.016ArgIle: 3.016 ± 0.049	2.818ArgLys: 2.818 ± 0.046	4.17ArgLeu: 4.17 ± 0.058	1.081ArgMet: 1.081 ± 0.026	2.043ArgAsn: 2.043 ± 0.039	1.686ArgPro: 1.686 ± 0.038	1.892ArgGln: 1.892 ± 0.041	1.68ArgArg: 1.68 ± 0.037	2.442ArgSer: 2.442 ± 0.044	2.053ArgThr: 2.053 ± 0.04	2.314ArgVal: 2.314 ± 0.046	0.605ArgTrp: 0.605 ± 0.022	1.903ArgTyr: 1.903 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.052SerAla: 5.052 ± 0.056	0.691SerCys: 0.691 ± 0.021	3.618SerAsp: 3.618 ± 0.055	3.09SerGlu: 3.09 ± 0.055	3.638SerPhe: 3.638 ± 0.057	5.331SerGly: 5.331 ± 0.077	1.203SerHis: 1.203 ± 0.034	4.628SerIle: 4.628 ± 0.059	3.896SerLys: 3.896 ± 0.054	6.778SerLeu: 6.778 ± 0.073	1.46SerMet: 1.46 ± 0.031	3.083SerAsn: 3.083 ± 0.056	2.396SerPro: 2.396 ± 0.038	2.346SerGln: 2.346 ± 0.039	2.544SerArg: 2.544 ± 0.045	4.708SerSer: 4.708 ± 0.067	3.797SerThr: 3.797 ± 0.056	4.216SerVal: 4.216 ± 0.059	1.004SerTrp: 1.004 ± 0.03	2.983SerTyr: 2.983 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	4.86ThrAla: 4.86 ± 0.061	0.382ThrCys: 0.382 ± 0.017	3.436ThrAsp: 3.436 ± 0.056	2.74ThrGlu: 2.74 ± 0.046	2.356ThrPhe: 2.356 ± 0.041	5.1ThrGly: 5.1 ± 0.071	1.127ThrHis: 1.127 ± 0.028	3.817ThrIle: 3.817 ± 0.059	3.076ThrLys: 3.076 ± 0.05	5.502ThrLeu: 5.502 ± 0.073	1.026ThrMet: 1.026 ± 0.027	2.499ThrAsn: 2.499 ± 0.05	2.726ThrPro: 2.726 ± 0.047	2.044ThrGln: 2.044 ± 0.043	2.118ThrArg: 2.118 ± 0.043	3.549ThrSer: 3.549 ± 0.062	3.467ThrThr: 3.467 ± 0.068	3.68ThrVal: 3.68 ± 0.052	0.673ThrTrp: 0.673 ± 0.024	2.324ThrTyr: 2.324 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	4.475ValAla: 4.475 ± 0.06	0.52ValCys: 0.52 ± 0.016	3.272ValAsp: 3.272 ± 0.046	2.922ValGlu: 2.922 ± 0.048	2.886ValPhe: 2.886 ± 0.048	3.782ValGly: 3.782 ± 0.052	1.199ValHis: 1.199 ± 0.029	4.305ValIle: 4.305 ± 0.064	3.758ValLys: 3.758 ± 0.054	5.769ValLeu: 5.769 ± 0.078	1.393ValMet: 1.393 ± 0.03	3.131ValAsn: 3.131 ± 0.043	2.465ValPro: 2.465 ± 0.046	2.326ValGln: 2.326 ± 0.04	2.47ValArg: 2.47 ± 0.051	4.222ValSer: 4.222 ± 0.065	3.55ValThr: 3.55 ± 0.053	3.66ValVal: 3.66 ± 0.061	0.734ValTrp: 0.734 ± 0.019	2.371ValTyr: 2.371 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.85TrpAla: 0.85 ± 0.024	0.128TrpCys: 0.128 ± 0.01	0.788TrpAsp: 0.788 ± 0.024	0.68TrpGlu: 0.68 ± 0.022	0.592TrpPhe: 0.592 ± 0.023	0.91TrpGly: 0.91 ± 0.028	0.311TrpHis: 0.311 ± 0.015	0.86TrpIle: 0.86 ± 0.024	0.841TrpLys: 0.841 ± 0.025	1.368TrpLeu: 1.368 ± 0.035	0.401TrpMet: 0.401 ± 0.019	0.744TrpAsn: 0.744 ± 0.025	0.432TrpPro: 0.432 ± 0.021	0.744TrpGln: 0.744 ± 0.024	0.566TrpArg: 0.566 ± 0.02	0.819TrpSer: 0.819 ± 0.027	0.744TrpThr: 0.744 ± 0.024	0.792TrpVal: 0.792 ± 0.023	0.26TrpTrp: 0.26 ± 0.015	0.559TrpTyr: 0.559 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.795TyrAla: 2.795 ± 0.047	0.382TyrCys: 0.382 ± 0.017	2.384TyrAsp: 2.384 ± 0.054	1.887TyrGlu: 1.887 ± 0.042	2.336TyrPhe: 2.336 ± 0.043	3.148TyrGly: 3.148 ± 0.054	0.945TyrHis: 0.945 ± 0.027	2.519TyrIle: 2.519 ± 0.043	2.687TyrLys: 2.687 ± 0.05	4.109TyrLeu: 4.109 ± 0.057	0.904TyrMet: 0.904 ± 0.025	2.619TyrAsn: 2.619 ± 0.052	1.888TyrPro: 1.888 ± 0.038	2.105TyrGln: 2.105 ± 0.043	1.842TyrArg: 1.842 ± 0.036	2.802TyrSer: 2.802 ± 0.049	2.408TyrThr: 2.408 ± 0.045	2.104TyrVal: 2.104 ± 0.04	0.628TyrTrp: 0.628 ± 0.022	2.208TyrTyr: 2.208 ± 0.05	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3837 proteins (1398744 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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