Amino acid dipepetide frequency for Stackebrandtia endophytica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.692AlaAla: 17.692 ± 0.143	0.926AlaCys: 0.926 ± 0.021	8.498AlaAsp: 8.498 ± 0.089	8.11AlaGlu: 8.11 ± 0.096	3.158AlaPhe: 3.158 ± 0.047	10.889AlaGly: 10.889 ± 0.098	2.268AlaHis: 2.268 ± 0.038	5.308AlaIle: 5.308 ± 0.059	2.693AlaLys: 2.693 ± 0.05	11.603AlaLeu: 11.603 ± 0.104	2.947AlaMet: 2.947 ± 0.048	2.254AlaAsn: 2.254 ± 0.038	5.275AlaPro: 5.275 ± 0.078	3.412AlaGln: 3.412 ± 0.053	7.797AlaArg: 7.797 ± 0.076	5.67AlaSer: 5.67 ± 0.057	7.682AlaThr: 7.682 ± 0.077	11.147AlaVal: 11.147 ± 0.107	1.721AlaTrp: 1.721 ± 0.036	2.182AlaTyr: 2.182 ± 0.037	0.0AlaXaa: 0.0 ± 0.0
Cys	0.842CysAla: 0.842 ± 0.024	0.09CysCys: 0.09 ± 0.008	0.626CysAsp: 0.626 ± 0.019	0.439CysGlu: 0.439 ± 0.018	0.22CysPhe: 0.22 ± 0.011	1.03CysGly: 1.03 ± 0.025	0.23CysHis: 0.23 ± 0.012	0.22CysIle: 0.22 ± 0.011	0.093CysLys: 0.093 ± 0.009	0.738CysLeu: 0.738 ± 0.023	0.148CysMet: 0.148 ± 0.01	0.166CysAsn: 0.166 ± 0.009	0.463CysPro: 0.463 ± 0.018	0.212CysGln: 0.212 ± 0.011	0.648CysArg: 0.648 ± 0.024	0.459CysSer: 0.459 ± 0.02	0.408CysThr: 0.408 ± 0.016	0.633CysVal: 0.633 ± 0.016	0.112CysTrp: 0.112 ± 0.008	0.17CysTyr: 0.17 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.158AspAla: 7.158 ± 0.07	0.529AspCys: 0.529 ± 0.021	4.72AspAsp: 4.72 ± 0.068	4.353AspGlu: 4.353 ± 0.058	1.774AspPhe: 1.774 ± 0.034	6.467AspGly: 6.467 ± 0.084	1.603AspHis: 1.603 ± 0.037	2.7AspIle: 2.7 ± 0.041	1.092AspLys: 1.092 ± 0.027	6.645AspLeu: 6.645 ± 0.078	1.105AspMet: 1.105 ± 0.027	1.403AspAsn: 1.403 ± 0.03	4.494AspPro: 4.494 ± 0.061	2.017AspGln: 2.017 ± 0.038	5.473AspArg: 5.473 ± 0.069	3.397AspSer: 3.397 ± 0.053	3.789AspThr: 3.789 ± 0.053	5.113AspVal: 5.113 ± 0.06	1.122AspTrp: 1.122 ± 0.029	1.44AspTyr: 1.44 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	6.736GluAla: 6.736 ± 0.076	0.419GluCys: 0.419 ± 0.017	2.719GluAsp: 2.719 ± 0.04	2.99GluGlu: 2.99 ± 0.051	1.871GluPhe: 1.871 ± 0.038	3.353GluGly: 3.353 ± 0.051	1.437GluHis: 1.437 ± 0.031	2.472GluIle: 2.472 ± 0.042	1.21GluLys: 1.21 ± 0.03	6.659GluLeu: 6.659 ± 0.077	1.014GluMet: 1.014 ± 0.027	1.155GluAsn: 1.155 ± 0.03	3.674GluPro: 3.674 ± 0.059	2.213GluGln: 2.213 ± 0.042	4.426GluArg: 4.426 ± 0.064	3.379GluSer: 3.379 ± 0.047	3.257GluThr: 3.257 ± 0.05	4.892GluVal: 4.892 ± 0.061	0.833GluTrp: 0.833 ± 0.025	1.441GluTyr: 1.441 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.65PheAla: 3.65 ± 0.045	0.286PheCys: 0.286 ± 0.015	2.466PheAsp: 2.466 ± 0.046	1.59PheGlu: 1.59 ± 0.035	0.854PhePhe: 0.854 ± 0.026	3.23PheGly: 3.23 ± 0.051	0.652PheHis: 0.652 ± 0.022	1.25PheIle: 1.25 ± 0.034	0.439PheLys: 0.439 ± 0.019	2.539PheLeu: 2.539 ± 0.043	0.475PheMet: 0.475 ± 0.017	0.76PheAsn: 0.76 ± 0.024	1.284PhePro: 1.284 ± 0.027	0.751PheGln: 0.751 ± 0.025	1.699PheArg: 1.699 ± 0.034	1.673PheSer: 1.673 ± 0.036	2.231PheThr: 2.231 ± 0.04	2.291PheVal: 2.291 ± 0.04	0.444PheTrp: 0.444 ± 0.018	0.621PheTyr: 0.621 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	8.593GlyAla: 8.593 ± 0.089	0.854GlyCys: 0.854 ± 0.024	5.844GlyAsp: 5.844 ± 0.08	4.944GlyGlu: 4.944 ± 0.069	3.239GlyPhe: 3.239 ± 0.039	7.537GlyGly: 7.537 ± 0.091	2.155GlyHis: 2.155 ± 0.04	4.091GlyIle: 4.091 ± 0.058	2.097GlyLys: 2.097 ± 0.042	8.773GlyLeu: 8.773 ± 0.09	2.229GlyMet: 2.229 ± 0.037	2.04GlyAsn: 2.04 ± 0.041	4.044GlyPro: 4.044 ± 0.058	2.691GlyGln: 2.691 ± 0.047	6.346GlyArg: 6.346 ± 0.071	5.033GlySer: 5.033 ± 0.067	5.292GlyThr: 5.292 ± 0.067	7.209GlyVal: 7.209 ± 0.076	1.68GlyTrp: 1.68 ± 0.037	2.459GlyTyr: 2.459 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.266HisAla: 2.266 ± 0.041	0.214HisCys: 0.214 ± 0.011	1.463HisAsp: 1.463 ± 0.031	1.067HisGlu: 1.067 ± 0.025	0.606HisPhe: 0.606 ± 0.02	2.097HisGly: 2.097 ± 0.04	0.736HisHis: 0.736 ± 0.023	0.916HisIle: 0.916 ± 0.024	0.296HisLys: 0.296 ± 0.015	2.393HisLeu: 2.393 ± 0.037	0.376HisMet: 0.376 ± 0.016	0.468HisAsn: 0.468 ± 0.018	1.627HisPro: 1.627 ± 0.032	0.734HisGln: 0.734 ± 0.024	2.354HisArg: 2.354 ± 0.047	1.141HisSer: 1.141 ± 0.028	1.21HisThr: 1.21 ± 0.029	1.535HisVal: 1.535 ± 0.032	0.371HisTrp: 0.371 ± 0.016	0.493HisTyr: 0.493 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	6.339IleAla: 6.339 ± 0.068	0.347IleCys: 0.347 ± 0.015	3.437IleAsp: 3.437 ± 0.043	2.69IleGlu: 2.69 ± 0.047	0.901IlePhe: 0.901 ± 0.025	4.631IleGly: 4.631 ± 0.058	0.828IleHis: 0.828 ± 0.023	1.644IleIle: 1.644 ± 0.034	0.81IleLys: 0.81 ± 0.022	3.532IleLeu: 3.532 ± 0.055	0.741IleMet: 0.741 ± 0.022	1.094IleAsn: 1.094 ± 0.027	2.468IlePro: 2.468 ± 0.036	0.937IleGln: 0.937 ± 0.023	2.858IleArg: 2.858 ± 0.043	2.36IleSer: 2.36 ± 0.036	3.042IleThr: 3.042 ± 0.046	3.749IleVal: 3.749 ± 0.049	0.512IleTrp: 0.512 ± 0.017	0.721IleTyr: 0.721 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.365LysAla: 2.365 ± 0.046	0.115LysCys: 0.115 ± 0.009	0.973LysAsp: 0.973 ± 0.029	0.94LysGlu: 0.94 ± 0.028	0.475LysPhe: 0.475 ± 0.019	1.253LysGly: 1.253 ± 0.033	0.472LysHis: 0.472 ± 0.019	0.887LysIle: 0.887 ± 0.03	0.686LysLys: 0.686 ± 0.03	2.055LysLeu: 2.055 ± 0.037	0.397LysMet: 0.397 ± 0.016	0.49LysAsn: 0.49 ± 0.016	1.376LysPro: 1.376 ± 0.033	0.686LysGln: 0.686 ± 0.021	1.594LysArg: 1.594 ± 0.033	1.208LysSer: 1.208 ± 0.03	1.263LysThr: 1.263 ± 0.034	1.746LysVal: 1.746 ± 0.037	0.252LysTrp: 0.252 ± 0.013	0.462LysTyr: 0.462 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	14.022LeuAla: 14.022 ± 0.121	0.784LeuCys: 0.784 ± 0.021	6.349LeuAsp: 6.349 ± 0.07	4.4LeuGlu: 4.4 ± 0.059	2.74LeuPhe: 2.74 ± 0.046	8.296LeuGly: 8.296 ± 0.095	2.003LeuHis: 2.003 ± 0.037	4.541LeuIle: 4.541 ± 0.062	1.708LeuLys: 1.708 ± 0.032	10.432LeuLeu: 10.432 ± 0.11	1.832LeuMet: 1.832 ± 0.032	2.109LeuAsn: 2.109 ± 0.035	5.713LeuPro: 5.713 ± 0.06	1.989LeuGln: 1.989 ± 0.038	7.712LeuArg: 7.712 ± 0.089	6.497LeuSer: 6.497 ± 0.06	7.125LeuThr: 7.125 ± 0.074	8.577LeuVal: 8.577 ± 0.085	1.398LeuTrp: 1.398 ± 0.034	1.803LeuTyr: 1.803 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.533MetAla: 2.533 ± 0.041	0.145MetCys: 0.145 ± 0.01	1.019MetAsp: 1.019 ± 0.021	0.858MetGlu: 0.858 ± 0.023	0.669MetPhe: 0.669 ± 0.023	1.402MetGly: 1.402 ± 0.033	0.339MetHis: 0.339 ± 0.015	0.939MetIle: 0.939 ± 0.026	0.455MetLys: 0.455 ± 0.019	2.116MetLeu: 2.116 ± 0.036	0.434MetMet: 0.434 ± 0.019	0.567MetAsn: 0.567 ± 0.017	1.209MetPro: 1.209 ± 0.027	0.463MetGln: 0.463 ± 0.015	1.634MetArg: 1.634 ± 0.032	1.75MetSer: 1.75 ± 0.033	1.937MetThr: 1.937 ± 0.033	1.746MetVal: 1.746 ± 0.035	0.266MetTrp: 0.266 ± 0.011	0.396MetTyr: 0.396 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.314AsnAla: 2.314 ± 0.041	0.181AsnCys: 0.181 ± 0.011	1.29AsnAsp: 1.29 ± 0.028	1.079AsnGlu: 1.079 ± 0.025	0.551AsnPhe: 0.551 ± 0.019	2.066AsnGly: 2.066 ± 0.05	0.517AsnHis: 0.517 ± 0.017	0.854AsnIle: 0.854 ± 0.024	0.397AsnLys: 0.397 ± 0.015	2.304AsnLeu: 2.304 ± 0.039	0.369AsnMet: 0.369 ± 0.017	0.556AsnAsn: 0.556 ± 0.021	1.72AsnPro: 1.72 ± 0.033	0.691AsnGln: 0.691 ± 0.021	1.779AsnArg: 1.779 ± 0.033	1.163AsnSer: 1.163 ± 0.029	1.294AsnThr: 1.294 ± 0.034	1.623AsnVal: 1.623 ± 0.031	0.375AsnTrp: 0.375 ± 0.014	0.469AsnTyr: 0.469 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.245ProAla: 6.245 ± 0.068	0.3ProCys: 0.3 ± 0.014	4.696ProAsp: 4.696 ± 0.065	3.821ProGlu: 3.821 ± 0.052	1.47ProPhe: 1.47 ± 0.033	5.574ProGly: 5.574 ± 0.08	1.297ProHis: 1.297 ± 0.03	2.22ProIle: 2.22 ± 0.032	1.13ProLys: 1.13 ± 0.031	4.616ProLeu: 4.616 ± 0.052	1.221ProMet: 1.221 ± 0.03	1.136ProAsn: 1.136 ± 0.029	3.514ProPro: 3.514 ± 0.088	1.91ProGln: 1.91 ± 0.034	3.401ProArg: 3.401 ± 0.05	3.164ProSer: 3.164 ± 0.051	3.797ProThr: 3.797 ± 0.058	5.078ProVal: 5.078 ± 0.065	0.847ProTrp: 0.847 ± 0.024	1.139ProTyr: 1.139 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.588GlnAla: 3.588 ± 0.051	0.193GlnCys: 0.193 ± 0.012	1.221GlnAsp: 1.221 ± 0.031	1.204GlnGlu: 1.204 ± 0.028	0.833GlnPhe: 0.833 ± 0.02	1.788GlnGly: 1.788 ± 0.034	0.683GlnHis: 0.683 ± 0.021	1.328GlnIle: 1.328 ± 0.027	0.448GlnLys: 0.448 ± 0.018	3.6GlnLeu: 3.6 ± 0.05	0.546GlnMet: 0.546 ± 0.017	0.557GlnAsn: 0.557 ± 0.02	2.004GlnPro: 2.004 ± 0.04	1.253GlnGln: 1.253 ± 0.034	2.628GlnArg: 2.628 ± 0.043	1.606GlnSer: 1.606 ± 0.032	1.545GlnThr: 1.545 ± 0.036	2.56GlnVal: 2.56 ± 0.035	0.561GlnTrp: 0.561 ± 0.018	0.645GlnTyr: 0.645 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	7.294ArgAla: 7.294 ± 0.078	0.581ArgCys: 0.581 ± 0.021	4.695ArgAsp: 4.695 ± 0.06	3.887ArgGlu: 3.887 ± 0.057	2.701ArgPhe: 2.701 ± 0.044	4.932ArgGly: 4.932 ± 0.06	2.171ArgHis: 2.171 ± 0.043	3.613ArgIle: 3.613 ± 0.047	1.566ArgLys: 1.566 ± 0.033	8.761ArgLeu: 8.761 ± 0.105	1.917ArgMet: 1.917 ± 0.036	1.534ArgAsn: 1.534 ± 0.033	4.052ArgPro: 4.052 ± 0.062	2.542ArgGln: 2.542 ± 0.044	7.395ArgArg: 7.395 ± 0.09	4.173ArgSer: 4.173 ± 0.06	4.095ArgThr: 4.095 ± 0.059	5.505ArgVal: 5.505 ± 0.057	1.305ArgTrp: 1.305 ± 0.03	1.939ArgTyr: 1.939 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	6.555SerAla: 6.555 ± 0.069	0.441SerCys: 0.441 ± 0.019	3.525SerAsp: 3.525 ± 0.048	2.95SerGlu: 2.95 ± 0.05	1.609SerPhe: 1.609 ± 0.033	6.028SerGly: 6.028 ± 0.071	1.241SerHis: 1.241 ± 0.029	2.434SerIle: 2.434 ± 0.041	1.124SerLys: 1.124 ± 0.032	5.146SerLeu: 5.146 ± 0.059	1.398SerMet: 1.398 ± 0.027	1.18SerAsn: 1.18 ± 0.029	3.425SerPro: 3.425 ± 0.048	1.719SerGln: 1.719 ± 0.03	4.117SerArg: 4.117 ± 0.048	3.315SerSer: 3.315 ± 0.067	3.743SerThr: 3.743 ± 0.057	4.685SerVal: 4.685 ± 0.054	0.939SerTrp: 0.939 ± 0.026	1.266SerTyr: 1.266 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	8.265ThrAla: 8.265 ± 0.089	0.446ThrCys: 0.446 ± 0.019	4.602ThrAsp: 4.602 ± 0.064	3.996ThrGlu: 3.996 ± 0.048	1.64ThrPhe: 1.64 ± 0.036	6.665ThrGly: 6.665 ± 0.076	1.123ThrHis: 1.123 ± 0.025	2.758ThrIle: 2.758 ± 0.043	1.213ThrLys: 1.213 ± 0.03	5.427ThrLeu: 5.427 ± 0.058	1.376ThrMet: 1.376 ± 0.028	1.237ThrAsn: 1.237 ± 0.031	3.889ThrPro: 3.889 ± 0.057	1.421ThrGln: 1.421 ± 0.029	3.848ThrArg: 3.848 ± 0.05	3.549ThrSer: 3.549 ± 0.054	4.256ThrThr: 4.256 ± 0.07	6.588ThrVal: 6.588 ± 0.069	0.967ThrTrp: 0.967 ± 0.025	1.256ThrTyr: 1.256 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	11.091ValAla: 11.091 ± 0.1	0.714ValCys: 0.714 ± 0.024	6.026ValAsp: 6.026 ± 0.063	5.006ValGlu: 5.006 ± 0.058	2.557ValPhe: 2.557 ± 0.04	6.821ValGly: 6.821 ± 0.069	1.715ValHis: 1.715 ± 0.036	4.042ValIle: 4.042 ± 0.046	1.648ValLys: 1.648 ± 0.031	8.353ValLeu: 8.353 ± 0.091	1.722ValMet: 1.722 ± 0.036	1.968ValAsn: 1.968 ± 0.035	4.335ValPro: 4.335 ± 0.053	1.736ValGln: 1.736 ± 0.035	5.324ValArg: 5.324 ± 0.054	5.056ValSer: 5.056 ± 0.057	6.376ValThr: 6.376 ± 0.085	8.113ValVal: 8.113 ± 0.09	1.147ValTrp: 1.147 ± 0.026	1.587ValTyr: 1.587 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.412TrpAla: 1.412 ± 0.03	0.171TrpCys: 0.171 ± 0.01	0.768TrpAsp: 0.768 ± 0.026	0.691TrpGlu: 0.691 ± 0.02	0.586TrpPhe: 0.586 ± 0.02	1.036TrpGly: 1.036 ± 0.026	0.42TrpHis: 0.42 ± 0.016	0.733TrpIle: 0.733 ± 0.024	0.297TrpLys: 0.297 ± 0.013	1.872TrpLeu: 1.872 ± 0.039	0.352TrpMet: 0.352 ± 0.014	0.47TrpAsn: 0.47 ± 0.018	0.805TrpPro: 0.805 ± 0.025	0.653TrpGln: 0.653 ± 0.02	1.6TrpArg: 1.6 ± 0.032	1.023TrpSer: 1.023 ± 0.025	0.932TrpThr: 0.932 ± 0.027	1.0TrpVal: 1.0 ± 0.029	0.445TrpTrp: 0.445 ± 0.017	0.389TrpTyr: 0.389 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.27TyrAla: 2.27 ± 0.039	0.209TyrCys: 0.209 ± 0.012	1.457TyrAsp: 1.457 ± 0.04	1.135TyrGlu: 1.135 ± 0.03	0.73TyrPhe: 0.73 ± 0.024	2.055TyrGly: 2.055 ± 0.04	0.472TyrHis: 0.472 ± 0.016	0.691TyrIle: 0.691 ± 0.019	0.293TyrLys: 0.293 ± 0.015	2.467TyrLeu: 2.467 ± 0.043	0.279TyrMet: 0.279 ± 0.014	0.448TyrAsn: 0.448 ± 0.019	1.203TyrPro: 1.203 ± 0.031	0.766TyrGln: 0.766 ± 0.022	2.03TyrArg: 2.03 ± 0.037	1.224TyrSer: 1.224 ± 0.027	1.247TyrThr: 1.247 ± 0.034	1.547TyrVal: 1.547 ± 0.03	0.355TyrTrp: 0.355 ± 0.015	0.495TyrTyr: 0.495 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5197 proteins (1637824 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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