Amino acid dipepetide frequency for Squirrel monkey polyomavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.319AlaAla: 4.319 ± 2.077
0.0AlaCys: 0.0 ± 0.0
0.48AlaAsp: 0.48 ± 0.477
4.319AlaGlu: 4.319 ± 2.237
2.879AlaPhe: 2.879 ± 0.81
0.48AlaGly: 0.48 ± 0.373
1.919AlaHis: 1.919 ± 1.142
3.839AlaIle: 3.839 ± 1.138
2.879AlaLys: 2.879 ± 1.076
7.198AlaLeu: 7.198 ± 2.502
2.399AlaMet: 2.399 ± 0.681
3.839AlaAsn: 3.839 ± 1.272
5.758AlaPro: 5.758 ± 1.552
3.359AlaGln: 3.359 ± 1.486
4.319AlaArg: 4.319 ± 1.936
4.319AlaSer: 4.319 ± 1.78
6.718AlaThr: 6.718 ± 3.184
6.238AlaVal: 6.238 ± 1.497
0.0AlaTrp: 0.0 ± 0.0
0.48AlaTyr: 0.48 ± 0.474
0.0AlaXaa: 0.0 ± 0.0
Cys
0.48CysAla: 0.48 ± 0.373
0.0CysCys: 0.0 ± 0.0
1.919CysAsp: 1.919 ± 1.034
0.0CysGlu: 0.0 ± 0.0
1.919CysPhe: 1.919 ± 0.992
0.96CysGly: 0.96 ± 0.479
0.48CysHis: 0.48 ± 0.373
0.96CysIle: 0.96 ± 0.479
3.359CysLys: 3.359 ± 1.74
1.919CysLeu: 1.919 ± 1.769
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.96CysGln: 0.96 ± 0.746
0.0CysArg: 0.0 ± 0.0
2.399CysSer: 2.399 ± 1.443
0.0CysThr: 0.0 ± 0.0
0.96CysVal: 0.96 ± 0.746
0.96CysTrp: 0.96 ± 0.479
1.44CysTyr: 1.44 ± 0.625
0.0CysXaa: 0.0 ± 0.0
Asp
2.399AspAla: 2.399 ± 0.855
0.96AspCys: 0.96 ± 0.62
2.879AspAsp: 2.879 ± 1.076
1.919AspGlu: 1.919 ± 1.113
1.44AspPhe: 1.44 ± 1.12
2.879AspGly: 2.879 ± 1.076
0.48AspHis: 0.48 ± 0.373
4.798AspIle: 4.798 ± 2.122
2.399AspLys: 2.399 ± 0.885
4.319AspLeu: 4.319 ± 0.727
1.44AspMet: 1.44 ± 0.88
1.919AspAsn: 1.919 ± 0.958
4.798AspPro: 4.798 ± 2.032
1.44AspGln: 1.44 ± 0.714
0.0AspArg: 0.0 ± 0.0
0.96AspSer: 0.96 ± 0.479
1.44AspThr: 1.44 ± 0.668
0.96AspVal: 0.96 ± 0.746
2.399AspTrp: 2.399 ± 1.219
3.839AspTyr: 3.839 ± 0.618
0.0AspXaa: 0.0 ± 0.0
Glu
4.798GluAla: 4.798 ± 2.577
2.399GluCys: 2.399 ± 1.158
6.238GluAsp: 6.238 ± 1.347
12.956GluGlu: 12.956 ± 2.623
1.919GluPhe: 1.919 ± 0.672
1.44GluGly: 1.44 ± 0.714
0.0GluHis: 0.0 ± 0.0
1.919GluIle: 1.919 ± 0.672
2.879GluLys: 2.879 ± 1.739
6.718GluLeu: 6.718 ± 1.431
1.44GluMet: 1.44 ± 0.482
5.278GluAsn: 5.278 ± 1.409
1.919GluPro: 1.919 ± 0.835
6.238GluGln: 6.238 ± 1.496
0.0GluArg: 0.0 ± 0.0
6.238GluSer: 6.238 ± 1.657
3.359GluThr: 3.359 ± 0.617
7.678GluVal: 7.678 ± 1.512
0.48GluTrp: 0.48 ± 0.373
3.839GluTyr: 3.839 ± 1.138
0.0GluXaa: 0.0 ± 0.0
Phe
1.919PheAla: 1.919 ± 0.828
1.919PheCys: 1.919 ± 1.113
1.44PheAsp: 1.44 ± 1.12
4.798PheGlu: 4.798 ± 1.358
0.96PhePhe: 0.96 ± 0.479
1.919PheGly: 1.919 ± 1.384
0.96PheHis: 0.96 ± 0.479
3.359PheIle: 3.359 ± 0.97
2.399PheLys: 2.399 ± 1.151
4.319PheLeu: 4.319 ± 2.339
0.48PheMet: 0.48 ± 0.53
0.96PheAsn: 0.96 ± 0.746
5.758PhePro: 5.758 ± 1.146
0.48PheGln: 0.48 ± 0.477
0.96PheArg: 0.96 ± 0.479
3.359PheSer: 3.359 ± 1.15
3.359PheThr: 3.359 ± 1.583
2.399PheVal: 2.399 ± 0.844
0.48PheTrp: 0.48 ± 0.373
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.359GlyAla: 3.359 ± 1.403
0.0GlyCys: 0.0 ± 0.0
4.798GlyAsp: 4.798 ± 1.57
2.879GlyGlu: 2.879 ± 0.901
2.879GlyPhe: 2.879 ± 0.671
6.238GlyGly: 6.238 ± 0.583
0.0GlyHis: 0.0 ± 0.0
2.399GlyIle: 2.399 ± 1.158
1.44GlyLys: 1.44 ± 0.714
12.956GlyLeu: 12.956 ± 1.531
0.48GlyMet: 0.48 ± 0.563
0.96GlyAsn: 0.96 ± 0.62
1.44GlyPro: 1.44 ± 0.88
5.278GlyGln: 5.278 ± 1.257
1.44GlyArg: 1.44 ± 0.85
0.96GlySer: 0.96 ± 0.62
0.96GlyThr: 0.96 ± 0.6
3.359GlyVal: 3.359 ± 1.341
0.0GlyTrp: 0.0 ± 0.0
0.48GlyTyr: 0.48 ± 0.477
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.48HisCys: 0.48 ± 0.373
0.0HisAsp: 0.0 ± 0.0
2.399HisGlu: 2.399 ± 0.679
0.96HisPhe: 0.96 ± 0.479
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.44HisIle: 1.44 ± 0.975
0.96HisLys: 0.96 ± 0.62
0.96HisLeu: 0.96 ± 0.746
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.44HisPro: 1.44 ± 0.82
0.0HisGln: 0.0 ± 0.0
2.879HisArg: 2.879 ± 0.801
1.44HisSer: 1.44 ± 0.714
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.44HisTyr: 1.44 ± 0.714
0.0HisXaa: 0.0 ± 0.0
Ile
6.238IleAla: 6.238 ± 2.968
0.96IleCys: 0.96 ± 0.479
3.359IleAsp: 3.359 ± 1.486
4.319IleGlu: 4.319 ± 1.716
2.399IlePhe: 2.399 ± 1.381
2.399IleGly: 2.399 ± 0.798
0.0IleHis: 0.0 ± 0.0
0.48IleIle: 0.48 ± 0.373
3.359IleLys: 3.359 ± 0.875
4.319IleLeu: 4.319 ± 0.691
1.919IleMet: 1.919 ± 1.161
2.399IleAsn: 2.399 ± 0.591
3.359IlePro: 3.359 ± 0.612
0.0IleGln: 0.0 ± 0.0
0.48IleArg: 0.48 ± 0.477
5.758IleSer: 5.758 ± 0.867
2.879IleThr: 2.879 ± 1.352
2.399IleVal: 2.399 ± 1.158
0.48IleTrp: 0.48 ± 0.563
1.44IleTyr: 1.44 ± 0.625
0.0IleXaa: 0.0 ± 0.0
Lys
1.919LysAla: 1.919 ± 1.113
2.399LysCys: 2.399 ± 1.776
1.44LysAsp: 1.44 ± 0.625
1.44LysGlu: 1.44 ± 1.12
0.96LysPhe: 0.96 ± 0.746
2.399LysGly: 2.399 ± 0.885
1.919LysHis: 1.919 ± 1.493
2.879LysIle: 2.879 ± 1.251
11.996LysLys: 11.996 ± 1.54
6.718LysLeu: 6.718 ± 2.438
0.96LysMet: 0.96 ± 0.62
6.238LysAsn: 6.238 ± 0.799
1.919LysPro: 1.919 ± 0.923
2.399LysGln: 2.399 ± 0.93
6.718LysArg: 6.718 ± 1.45
5.758LysSer: 5.758 ± 1.189
4.319LysThr: 4.319 ± 1.852
3.839LysVal: 3.839 ± 0.907
0.48LysTrp: 0.48 ± 0.373
1.44LysTyr: 1.44 ± 0.88
0.0LysXaa: 0.0 ± 0.0
Leu
5.278LeuAla: 5.278 ± 2.49
2.399LeuCys: 2.399 ± 0.985
2.879LeuAsp: 2.879 ± 1.427
8.637LeuGlu: 8.637 ± 1.456
5.278LeuPhe: 5.278 ± 1.087
6.238LeuGly: 6.238 ± 1.379
3.359LeuHis: 3.359 ± 0.612
7.198LeuIle: 7.198 ± 1.13
3.359LeuLys: 3.359 ± 1.321
12.956LeuLeu: 12.956 ± 3.413
4.319LeuMet: 4.319 ± 1.087
9.597LeuAsn: 9.597 ± 2.136
8.637LeuPro: 8.637 ± 1.835
5.278LeuGln: 5.278 ± 1.472
1.919LeuArg: 1.919 ± 0.835
3.839LeuSer: 3.839 ± 1.561
8.157LeuThr: 8.157 ± 2.486
3.839LeuVal: 3.839 ± 1.271
1.919LeuTrp: 1.919 ± 1.018
5.758LeuTyr: 5.758 ± 1.486
0.0LeuXaa: 0.0 ± 0.0
Met
2.879MetAla: 2.879 ± 1.268
0.48MetCys: 0.48 ± 0.373
1.44MetAsp: 1.44 ± 0.852
1.919MetGlu: 1.919 ± 1.24
0.0MetPhe: 0.0 ± 0.0
0.96MetGly: 0.96 ± 0.6
0.96MetHis: 0.96 ± 0.62
0.48MetIle: 0.48 ± 0.477
1.44MetLys: 1.44 ± 0.714
1.919MetLeu: 1.919 ± 0.736
0.0MetMet: 0.0 ± 0.0
0.48MetAsn: 0.48 ± 0.373
3.359MetPro: 3.359 ± 0.659
2.399MetGln: 2.399 ± 1.053
0.96MetArg: 0.96 ± 0.62
0.48MetSer: 0.48 ± 0.477
0.96MetThr: 0.96 ± 0.689
0.0MetVal: 0.0 ± 0.0
0.48MetTrp: 0.48 ± 0.477
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.879AsnAla: 2.879 ± 0.469
0.0AsnCys: 0.0 ± 0.0
0.48AsnAsp: 0.48 ± 0.477
2.879AsnGlu: 2.879 ± 1.437
3.359AsnPhe: 3.359 ± 1.632
0.96AsnGly: 0.96 ± 0.479
0.96AsnHis: 0.96 ± 0.479
2.399AsnIle: 2.399 ± 0.985
2.399AsnLys: 2.399 ± 1.381
6.718AsnLeu: 6.718 ± 1.683
1.44AsnMet: 1.44 ± 0.727
0.0AsnAsn: 0.0 ± 0.0
3.359AsnPro: 3.359 ± 0.984
3.359AsnGln: 3.359 ± 0.963
2.399AsnArg: 2.399 ± 1.275
0.96AsnSer: 0.96 ± 0.653
6.238AsnThr: 6.238 ± 2.343
2.879AsnVal: 2.879 ± 1.428
0.0AsnTrp: 0.0 ± 0.0
1.919AsnTyr: 1.919 ± 0.869
0.0AsnXaa: 0.0 ± 0.0
Pro
0.48ProAla: 0.48 ± 0.474
0.48ProCys: 0.48 ± 0.477
4.319ProAsp: 4.319 ± 1.308
2.879ProGlu: 2.879 ± 0.885
2.399ProPhe: 2.399 ± 0.679
4.798ProGly: 4.798 ± 1.259
0.0ProHis: 0.0 ± 0.0
3.359ProIle: 3.359 ± 1.578
2.399ProLys: 2.399 ± 0.985
6.238ProLeu: 6.238 ± 1.245
2.879ProMet: 2.879 ± 0.671
2.399ProAsn: 2.399 ± 1.053
3.839ProPro: 3.839 ± 0.713
3.359ProGln: 3.359 ± 0.951
5.758ProArg: 5.758 ± 2.295
6.238ProSer: 6.238 ± 1.182
2.879ProThr: 2.879 ± 0.865
2.879ProVal: 2.879 ± 1.719
0.0ProTrp: 0.0 ± 0.0
0.96ProTyr: 0.96 ± 0.6
0.0ProXaa: 0.0 ± 0.0
Gln
3.839GlnAla: 3.839 ± 0.995
0.48GlnCys: 0.48 ± 0.477
1.44GlnAsp: 1.44 ± 0.714
1.919GlnGlu: 1.919 ± 0.923
0.96GlnPhe: 0.96 ± 0.479
2.399GlnGly: 2.399 ± 0.591
0.48GlnHis: 0.48 ± 0.373
0.48GlnIle: 0.48 ± 0.373
6.238GlnLys: 6.238 ± 1.379
5.278GlnLeu: 5.278 ± 1.208
1.44GlnMet: 1.44 ± 0.677
2.399GlnAsn: 2.399 ± 0.591
1.919GlnPro: 1.919 ± 1.049
1.919GlnGln: 1.919 ± 1.493
3.359GlnArg: 3.359 ± 1.823
2.879GlnSer: 2.879 ± 0.718
2.399GlnThr: 2.399 ± 1.443
3.359GlnVal: 3.359 ± 0.963
1.919GlnTrp: 1.919 ± 0.672
2.399GlnTyr: 2.399 ± 1.151
0.0GlnXaa: 0.0 ± 0.0
Arg
0.48ArgAla: 0.48 ± 0.563
0.0ArgCys: 0.0 ± 0.0
2.879ArgAsp: 2.879 ± 0.776
2.879ArgGlu: 2.879 ± 0.718
3.359ArgPhe: 3.359 ± 0.609
0.96ArgGly: 0.96 ± 0.6
0.48ArgHis: 0.48 ± 0.373
4.319ArgIle: 4.319 ± 2.147
5.758ArgLys: 5.758 ± 1.054
2.399ArgLeu: 2.399 ± 1.053
0.48ArgMet: 0.48 ± 0.477
0.96ArgAsn: 0.96 ± 0.479
0.0ArgPro: 0.0 ± 0.0
0.0ArgGln: 0.0 ± 0.0
2.399ArgArg: 2.399 ± 0.855
5.278ArgSer: 5.278 ± 2.571
3.359ArgThr: 3.359 ± 1.823
2.879ArgVal: 2.879 ± 1.421
1.44ArgTrp: 1.44 ± 0.85
5.758ArgTyr: 5.758 ± 2.21
0.0ArgXaa: 0.0 ± 0.0
Ser
10.077SerAla: 10.077 ± 2.497
1.919SerCys: 1.919 ± 0.992
1.44SerAsp: 1.44 ± 1.12
4.798SerGlu: 4.798 ± 1.043
1.919SerPhe: 1.919 ± 1.181
3.359SerGly: 3.359 ± 0.671
0.48SerHis: 0.48 ± 0.613
0.96SerIle: 0.96 ± 0.479
4.319SerLys: 4.319 ± 1.699
7.198SerLeu: 7.198 ± 1.665
0.48SerMet: 0.48 ± 0.477
1.919SerAsn: 1.919 ± 1.493
3.359SerPro: 3.359 ± 1.578
0.96SerGln: 0.96 ± 0.653
3.359SerArg: 3.359 ± 1.247
1.44SerSer: 1.44 ± 0.722
6.718SerThr: 6.718 ± 1.65
2.879SerVal: 2.879 ± 1.089
4.798SerTrp: 4.798 ± 1.452
1.919SerTyr: 1.919 ± 0.869
0.0SerXaa: 0.0 ± 0.0
Thr
4.798ThrAla: 4.798 ± 1.294
1.44ThrCys: 1.44 ± 0.82
2.399ThrAsp: 2.399 ± 0.885
4.798ThrGlu: 4.798 ± 1.306
2.399ThrPhe: 2.399 ± 1.146
3.839ThrGly: 3.839 ± 1.278
0.48ThrHis: 0.48 ± 0.477
2.879ThrIle: 2.879 ± 1.181
3.839ThrLys: 3.839 ± 0.644
9.597ThrLeu: 9.597 ± 1.003
0.0ThrMet: 0.0 ± 0.0
3.359ThrAsn: 3.359 ± 1.228
4.798ThrPro: 4.798 ± 0.838
3.839ThrGln: 3.839 ± 0.669
2.879ThrArg: 2.879 ± 0.718
1.919ThrSer: 1.919 ± 1.198
1.919ThrThr: 1.919 ± 0.619
4.798ThrVal: 4.798 ± 1.425
0.0ThrTrp: 0.0 ± 0.0
1.919ThrTyr: 1.919 ± 0.736
0.0ThrXaa: 0.0 ± 0.0
Val
5.278ValAla: 5.278 ± 1.85
1.44ValCys: 1.44 ± 0.82
3.359ValAsp: 3.359 ± 0.875
4.319ValGlu: 4.319 ± 1.282
1.44ValPhe: 1.44 ± 1.12
3.839ValGly: 3.839 ± 2.372
0.0ValHis: 0.0 ± 0.0
1.919ValIle: 1.919 ± 0.958
3.839ValLys: 3.839 ± 1.494
4.319ValLeu: 4.319 ± 1.63
0.48ValMet: 0.48 ± 0.373
2.879ValAsn: 2.879 ± 1.739
1.44ValPro: 1.44 ± 0.482
4.319ValGln: 4.319 ± 0.791
5.278ValArg: 5.278 ± 2.408
4.319ValSer: 4.319 ± 1.227
3.359ValThr: 3.359 ± 0.893
3.359ValVal: 3.359 ± 1.275
0.96ValTrp: 0.96 ± 0.864
0.48ValTyr: 0.48 ± 0.373
0.0ValXaa: 0.0 ± 0.0
Trp
3.359TrpAla: 3.359 ± 1.652
0.48TrpCys: 0.48 ± 0.373
0.0TrpAsp: 0.0 ± 0.0
4.319TrpGlu: 4.319 ± 1.49
2.399TrpPhe: 2.399 ± 0.798
0.48TrpGly: 0.48 ± 0.613
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.48TrpLys: 0.48 ± 0.373
3.359TrpLeu: 3.359 ± 1.658
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.96TrpGln: 0.96 ± 0.62
0.48TrpArg: 0.48 ± 0.373
0.48TrpSer: 0.48 ± 0.373
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.48TrpTrp: 0.48 ± 0.373
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.44TyrAla: 1.44 ± 0.722
0.48TyrCys: 0.48 ± 0.373
0.48TyrAsp: 0.48 ± 0.474
3.359TyrGlu: 3.359 ± 1.652
2.399TyrPhe: 2.399 ± 1.116
5.758TyrGly: 5.758 ± 1.215
1.44TyrHis: 1.44 ± 0.714
2.879TyrIle: 2.879 ± 0.671
2.399TyrLys: 2.399 ± 0.985
1.44TyrLeu: 1.44 ± 1.12
0.48TyrMet: 0.48 ± 0.373
0.0TyrAsn: 0.0 ± 0.0
1.44TyrPro: 1.44 ± 0.975
0.96TyrGln: 0.96 ± 0.62
0.48TyrArg: 0.48 ± 0.477
5.278TyrSer: 5.278 ± 1.375
2.879TyrThr: 2.879 ± 1.69
1.919TyrVal: 1.919 ± 1.049
0.0TyrTrp: 0.0 ± 0.0
2.399TyrTyr: 2.399 ± 1.528
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2085 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski