Amino acid dipepetide frequency for Abiotrophia defectiva ATCC 49176

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.534AlaAla: 7.534 ± 0.324
0.617AlaCys: 0.617 ± 0.033
5.016AlaAsp: 5.016 ± 0.141
4.906AlaGlu: 4.906 ± 0.105
3.349AlaPhe: 3.349 ± 0.088
6.138AlaGly: 6.138 ± 0.116
1.753AlaHis: 1.753 ± 0.06
6.104AlaIle: 6.104 ± 0.261
5.931AlaLys: 5.931 ± 0.396
9.516AlaLeu: 9.516 ± 0.177
2.336AlaMet: 2.336 ± 0.059
3.569AlaAsn: 3.569 ± 0.094
2.954AlaPro: 2.954 ± 0.084
5.07AlaGln: 5.07 ± 0.157
3.481AlaArg: 3.481 ± 0.086
5.828AlaSer: 5.828 ± 0.113
4.665AlaThr: 4.665 ± 0.16
5.787AlaVal: 5.787 ± 0.142
0.959AlaTrp: 0.959 ± 0.045
3.403AlaTyr: 3.403 ± 0.083
0.0AlaXaa: 0.0 ± 0.0
Cys
0.429CysAla: 0.429 ± 0.029
0.072CysCys: 0.072 ± 0.011
0.318CysAsp: 0.318 ± 0.023
0.276CysGlu: 0.276 ± 0.024
0.307CysPhe: 0.307 ± 0.022
0.509CysGly: 0.509 ± 0.031
0.233CysHis: 0.233 ± 0.021
0.298CysIle: 0.298 ± 0.021
0.171CysLys: 0.171 ± 0.019
0.856CysLeu: 0.856 ± 0.047
0.127CysMet: 0.127 ± 0.014
0.161CysAsn: 0.161 ± 0.018
0.289CysPro: 0.289 ± 0.025
0.515CysGln: 0.515 ± 0.032
0.29CysArg: 0.29 ± 0.023
0.295CysSer: 0.295 ± 0.022
0.194CysThr: 0.194 ± 0.018
0.356CysVal: 0.356 ± 0.026
0.067CysTrp: 0.067 ± 0.012
0.24CysTyr: 0.24 ± 0.022
0.0CysXaa: 0.0 ± 0.0
Asp
4.59AspAla: 4.59 ± 0.337
0.349AspCys: 0.349 ± 0.024
2.533AspAsp: 2.533 ± 0.075
3.039AspGlu: 3.039 ± 0.074
2.97AspPhe: 2.97 ± 0.072
3.727AspGly: 3.727 ± 0.143
1.277AspHis: 1.277 ± 0.049
3.215AspIle: 3.215 ± 0.087
3.456AspLys: 3.456 ± 0.12
6.631AspLeu: 6.631 ± 0.129
1.352AspMet: 1.352 ± 0.049
1.894AspAsn: 1.894 ± 0.058
2.243AspPro: 2.243 ± 0.078
4.003AspGln: 4.003 ± 0.11
2.453AspArg: 2.453 ± 0.067
3.093AspSer: 3.093 ± 0.076
2.403AspThr: 2.403 ± 0.075
3.451AspVal: 3.451 ± 0.091
0.93AspTrp: 0.93 ± 0.049
3.088AspTyr: 3.088 ± 0.073
0.0AspXaa: 0.0 ± 0.0
Glu
7.366GluAla: 7.366 ± 0.151
0.338GluCys: 0.338 ± 0.026
3.611GluAsp: 3.611 ± 0.075
5.043GluGlu: 5.043 ± 0.113
2.103GluPhe: 2.103 ± 0.079
4.218GluGly: 4.218 ± 0.084
1.086GluHis: 1.086 ± 0.045
3.867GluIle: 3.867 ± 0.107
3.287GluLys: 3.287 ± 0.11
6.396GluLeu: 6.396 ± 0.137
1.515GluMet: 1.515 ± 0.054
2.396GluAsn: 2.396 ± 0.076
2.07GluPro: 2.07 ± 0.063
2.788GluGln: 2.788 ± 0.091
3.419GluArg: 3.419 ± 0.093
3.644GluSer: 3.644 ± 0.086
3.287GluThr: 3.287 ± 0.072
4.765GluVal: 4.765 ± 0.098
0.786GluTrp: 0.786 ± 0.04
1.675GluTyr: 1.675 ± 0.061
0.0GluXaa: 0.0 ± 0.0
Phe
2.941PheAla: 2.941 ± 0.076
0.287PheCys: 0.287 ± 0.022
2.455PheAsp: 2.455 ± 0.081
2.522PheGlu: 2.522 ± 0.068
1.85PhePhe: 1.85 ± 0.063
2.941PheGly: 2.941 ± 0.076
0.781PheHis: 0.781 ± 0.036
2.395PheIle: 2.395 ± 0.075
2.186PheLys: 2.186 ± 0.064
4.119PheLeu: 4.119 ± 0.109
0.975PheMet: 0.975 ± 0.044
1.726PheAsn: 1.726 ± 0.058
1.355PhePro: 1.355 ± 0.052
1.812PheGln: 1.812 ± 0.058
1.66PheArg: 1.66 ± 0.059
2.533PheSer: 2.533 ± 0.072
2.094PheThr: 2.094 ± 0.112
2.804PheVal: 2.804 ± 0.08
0.471PheTrp: 0.471 ± 0.03
1.755PheTyr: 1.755 ± 0.06
0.0PheXaa: 0.0 ± 0.0
Gly
5.171GlyAla: 5.171 ± 0.107
0.455GlyCys: 0.455 ± 0.028
3.491GlyAsp: 3.491 ± 0.097
3.324GlyGlu: 3.324 ± 0.089
2.97GlyPhe: 2.97 ± 0.081
4.474GlyGly: 4.474 ± 0.1
1.639GlyHis: 1.639 ± 0.052
4.464GlyIle: 4.464 ± 0.096
3.998GlyLys: 3.998 ± 0.09
7.921GlyLeu: 7.921 ± 0.145
1.724GlyMet: 1.724 ± 0.066
2.383GlyAsn: 2.383 ± 0.068
1.983GlyPro: 1.983 ± 0.059
4.748GlyGln: 4.748 ± 0.132
3.252GlyArg: 3.252 ± 0.085
3.675GlySer: 3.675 ± 0.099
3.889GlyThr: 3.889 ± 0.2
4.874GlyVal: 4.874 ± 0.12
0.806GlyTrp: 0.806 ± 0.044
2.996GlyTyr: 2.996 ± 0.07
0.0GlyXaa: 0.0 ± 0.0
His
1.422HisAla: 1.422 ± 0.05
0.173HisCys: 0.173 ± 0.017
1.166HisAsp: 1.166 ± 0.045
1.228HisGlu: 1.228 ± 0.042
1.109HisPhe: 1.109 ± 0.047
1.262HisGly: 1.262 ± 0.055
0.716HisHis: 0.716 ± 0.043
1.125HisIle: 1.125 ± 0.056
0.816HisLys: 0.816 ± 0.042
2.37HisLeu: 2.37 ± 0.072
0.413HisMet: 0.413 ± 0.027
0.651HisAsn: 0.651 ± 0.034
1.108HisPro: 1.108 ± 0.044
1.31HisGln: 1.31 ± 0.049
0.962HisArg: 0.962 ± 0.041
1.08HisSer: 1.08 ± 0.048
0.961HisThr: 0.961 ± 0.042
1.316HisVal: 1.316 ± 0.055
0.243HisTrp: 0.243 ± 0.019
1.298HisTyr: 1.298 ± 0.05
0.0HisXaa: 0.0 ± 0.0
Ile
4.959IleAla: 4.959 ± 0.114
0.447IleCys: 0.447 ± 0.026
3.549IleAsp: 3.549 ± 0.103
4.474IleGlu: 4.474 ± 0.109
2.393IlePhe: 2.393 ± 0.073
4.393IleGly: 4.393 ± 0.105
1.204IleHis: 1.204 ± 0.042
3.745IleIle: 3.745 ± 0.099
3.465IleLys: 3.465 ± 0.085
6.179IleLeu: 6.179 ± 0.131
1.383IleMet: 1.383 ± 0.054
2.512IleAsn: 2.512 ± 0.1
2.478IlePro: 2.478 ± 0.071
2.987IleGln: 2.987 ± 0.066
2.825IleArg: 2.825 ± 0.071
3.528IleSer: 3.528 ± 0.08
2.956IleThr: 2.956 ± 0.097
4.001IleVal: 4.001 ± 0.091
0.666IleTrp: 0.666 ± 0.034
2.112IleTyr: 2.112 ± 0.065
0.0IleXaa: 0.0 ± 0.0
Lys
5.105LysAla: 5.105 ± 0.211
0.21LysCys: 0.21 ± 0.02
3.401LysAsp: 3.401 ± 0.167
4.337LysGlu: 4.337 ± 0.1
1.571LysPhe: 1.571 ± 0.05
3.518LysGly: 3.518 ± 0.087
0.967LysHis: 0.967 ± 0.037
3.151LysIle: 3.151 ± 0.092
3.448LysLys: 3.448 ± 0.115
4.947LysLeu: 4.947 ± 0.087
1.447LysMet: 1.447 ± 0.058
2.08LysAsn: 2.08 ± 0.1
2.161LysPro: 2.161 ± 0.07
2.982LysGln: 2.982 ± 0.091
2.868LysArg: 2.868 ± 0.088
2.972LysSer: 2.972 ± 0.084
3.205LysThr: 3.205 ± 0.098
4.306LysVal: 4.306 ± 0.094
0.545LysTrp: 0.545 ± 0.034
1.592LysTyr: 1.592 ± 0.054
0.0LysXaa: 0.0 ± 0.0
Leu
11.548LeuAla: 11.548 ± 0.223
0.633LeuCys: 0.633 ± 0.035
6.42LeuAsp: 6.42 ± 0.128
7.056LeuGlu: 7.056 ± 0.138
3.843LeuPhe: 3.843 ± 0.1
7.283LeuGly: 7.283 ± 0.143
1.74LeuHis: 1.74 ± 0.058
6.29LeuIle: 6.29 ± 0.13
5.884LeuLys: 5.884 ± 0.109
10.346LeuLeu: 10.346 ± 0.205
2.68LeuMet: 2.68 ± 0.083
4.189LeuAsn: 4.189 ± 0.098
4.399LeuPro: 4.399 ± 0.1
3.564LeuGln: 3.564 ± 0.077
4.132LeuArg: 4.132 ± 0.087
7.107LeuSer: 7.107 ± 0.132
6.353LeuThr: 6.353 ± 0.117
8.159LeuVal: 8.159 ± 0.167
0.936LeuTrp: 0.936 ± 0.048
3.329LeuTyr: 3.329 ± 0.078
0.0LeuXaa: 0.0 ± 0.0
Met
2.277MetAla: 2.277 ± 0.071
0.091MetCys: 0.091 ± 0.012
1.271MetAsp: 1.271 ± 0.043
1.416MetGlu: 1.416 ± 0.052
0.654MetPhe: 0.654 ± 0.034
1.67MetGly: 1.67 ± 0.062
0.316MetHis: 0.316 ± 0.022
1.585MetIle: 1.585 ± 0.061
1.781MetLys: 1.781 ± 0.058
1.995MetLeu: 1.995 ± 0.062
0.781MetMet: 0.781 ± 0.044
1.057MetAsn: 1.057 ± 0.043
0.987MetPro: 0.987 ± 0.04
1.013MetGln: 1.013 ± 0.043
1.165MetArg: 1.165 ± 0.047
1.579MetSer: 1.579 ± 0.055
1.967MetThr: 1.967 ± 0.062
1.729MetVal: 1.729 ± 0.066
0.153MetTrp: 0.153 ± 0.014
0.502MetTyr: 0.502 ± 0.027
0.0MetXaa: 0.0 ± 0.0
Asn
2.874AsnAla: 2.874 ± 0.173
0.191AsnCys: 0.191 ± 0.018
1.848AsnAsp: 1.848 ± 0.081
2.122AsnGlu: 2.122 ± 0.076
1.602AsnPhe: 1.602 ± 0.052
2.828AsnGly: 2.828 ± 0.1
0.925AsnHis: 0.925 ± 0.043
2.222AsnIle: 2.222 ± 0.075
2.122AsnLys: 2.122 ± 0.071
4.009AsnLeu: 4.009 ± 0.092
0.879AsnMet: 0.879 ± 0.036
1.457AsnAsn: 1.457 ± 0.076
2.114AsnPro: 2.114 ± 0.068
2.714AsnGln: 2.714 ± 0.077
1.956AsnArg: 1.956 ± 0.06
1.921AsnSer: 1.921 ± 0.05
1.765AsnThr: 1.765 ± 0.064
2.337AsnVal: 2.337 ± 0.061
0.52AsnTrp: 0.52 ± 0.033
1.6AsnTyr: 1.6 ± 0.057
0.0AsnXaa: 0.0 ± 0.0
Pro
3.442ProAla: 3.442 ± 0.118
0.171ProCys: 0.171 ± 0.018
2.582ProAsp: 2.582 ± 0.112
3.202ProGlu: 3.202 ± 0.075
1.579ProPhe: 1.579 ± 0.052
2.564ProGly: 2.564 ± 0.087
0.887ProHis: 0.887 ± 0.04
2.306ProIle: 2.306 ± 0.057
1.992ProLys: 1.992 ± 0.053
3.623ProLeu: 3.623 ± 0.097
0.956ProMet: 0.956 ± 0.065
1.726ProAsn: 1.726 ± 0.065
0.812ProPro: 0.812 ± 0.077
1.998ProGln: 1.998 ± 0.076
1.354ProArg: 1.354 ± 0.052
2.68ProSer: 2.68 ± 0.07
2.31ProThr: 2.31 ± 0.153
3.174ProVal: 3.174 ± 0.109
0.413ProTrp: 0.413 ± 0.029
1.51ProTyr: 1.51 ± 0.062
0.0ProXaa: 0.0 ± 0.0
Gln
7.689GlnAla: 7.689 ± 0.31
0.184GlnCys: 0.184 ± 0.019
3.261GlnAsp: 3.261 ± 0.092
4.448GlnGlu: 4.448 ± 0.096
1.634GlnPhe: 1.634 ± 0.054
3.745GlnGly: 3.745 ± 0.103
1.013GlnHis: 1.013 ± 0.043
2.731GlnIle: 2.731 ± 0.078
2.147GlnLys: 2.147 ± 0.057
5.525GlnLeu: 5.525 ± 0.131
1.166GlnMet: 1.166 ± 0.046
1.652GlnAsn: 1.652 ± 0.058
2.041GlnPro: 2.041 ± 0.093
2.196GlnGln: 2.196 ± 0.082
2.073GlnArg: 2.073 ± 0.065
2.748GlnSer: 2.748 ± 0.088
2.822GlnThr: 2.822 ± 0.089
5.384GlnVal: 5.384 ± 0.132
0.52GlnTrp: 0.52 ± 0.029
1.566GlnTyr: 1.566 ± 0.062
0.0GlnXaa: 0.0 ± 0.0
Arg
2.933ArgAla: 2.933 ± 0.084
0.223ArgCys: 0.223 ± 0.022
2.442ArgAsp: 2.442 ± 0.065
2.763ArgGlu: 2.763 ± 0.076
2.034ArgPhe: 2.034 ± 0.057
2.414ArgGly: 2.414 ± 0.073
1.134ArgHis: 1.134 ± 0.049
2.75ArgIle: 2.75 ± 0.066
2.38ArgLys: 2.38 ± 0.077
5.531ArgLeu: 5.531 ± 0.113
1.15ArgMet: 1.15 ± 0.046
1.553ArgAsn: 1.553 ± 0.056
1.768ArgPro: 1.768 ± 0.07
3.316ArgGln: 3.316 ± 0.082
2.517ArgArg: 2.517 ± 0.086
2.096ArgSer: 2.096 ± 0.056
1.961ArgThr: 1.961 ± 0.06
3.044ArgVal: 3.044 ± 0.088
0.467ArgTrp: 0.467 ± 0.031
2.14ArgTyr: 2.14 ± 0.067
0.0ArgXaa: 0.0 ± 0.0
Ser
4.288SerAla: 4.288 ± 0.101
0.339SerCys: 0.339 ± 0.022
3.287SerAsp: 3.287 ± 0.093
3.357SerGlu: 3.357 ± 0.103
2.466SerPhe: 2.466 ± 0.068
4.267SerGly: 4.267 ± 0.091
1.481SerHis: 1.481 ± 0.059
3.363SerIle: 3.363 ± 0.085
3.016SerLys: 3.016 ± 0.084
6.924SerLeu: 6.924 ± 0.132
1.249SerMet: 1.249 ± 0.049
2.282SerAsn: 2.282 ± 0.074
2.346SerPro: 2.346 ± 0.065
4.319SerGln: 4.319 ± 0.115
2.709SerArg: 2.709 ± 0.074
4.358SerSer: 4.358 ± 0.171
2.868SerThr: 2.868 ± 0.107
3.84SerVal: 3.84 ± 0.087
0.648SerTrp: 0.648 ± 0.033
2.205SerTyr: 2.205 ± 0.063
0.0SerXaa: 0.0 ± 0.0
Thr
4.236ThrAla: 4.236 ± 0.146
0.302ThrCys: 0.302 ± 0.022
2.793ThrAsp: 2.793 ± 0.101
2.962ThrGlu: 2.962 ± 0.08
2.31ThrPhe: 2.31 ± 0.122
4.07ThrGly: 4.07 ± 0.109
1.119ThrHis: 1.119 ± 0.047
3.683ThrIle: 3.683 ± 0.085
2.806ThrLys: 2.806 ± 0.102
5.789ThrLeu: 5.789 ± 0.108
1.085ThrMet: 1.085 ± 0.048
1.992ThrAsn: 1.992 ± 0.066
3.086ThrPro: 3.086 ± 0.3
2.514ThrGln: 2.514 ± 0.071
2.062ThrArg: 2.062 ± 0.068
3.365ThrSer: 3.365 ± 0.113
2.843ThrThr: 2.843 ± 0.093
4.215ThrVal: 4.215 ± 0.179
0.693ThrTrp: 0.693 ± 0.039
2.215ThrTyr: 2.215 ± 0.079
0.0ThrXaa: 0.0 ± 0.0
Val
6.668ValAla: 6.668 ± 0.113
0.501ValCys: 0.501 ± 0.03
4.393ValAsp: 4.393 ± 0.114
4.3ValGlu: 4.3 ± 0.096
2.731ValPhe: 2.731 ± 0.078
4.937ValGly: 4.937 ± 0.133
1.287ValHis: 1.287 ± 0.047
4.429ValIle: 4.429 ± 0.111
3.934ValLys: 3.934 ± 0.11
7.104ValLeu: 7.104 ± 0.139
1.755ValMet: 1.755 ± 0.064
2.939ValAsn: 2.939 ± 0.089
3.138ValPro: 3.138 ± 0.13
2.926ValGln: 2.926 ± 0.08
2.812ValArg: 2.812 ± 0.074
4.561ValSer: 4.561 ± 0.092
5.092ValThr: 5.092 ± 0.208
5.337ValVal: 5.337 ± 0.13
0.701ValTrp: 0.701 ± 0.034
2.465ValTyr: 2.465 ± 0.065
0.0ValXaa: 0.0 ± 0.0
Trp
0.758TrpAla: 0.758 ± 0.042
0.101TrpCys: 0.101 ± 0.013
0.522TrpAsp: 0.522 ± 0.033
0.563TrpGlu: 0.563 ± 0.037
0.465TrpPhe: 0.465 ± 0.031
0.731TrpGly: 0.731 ± 0.034
0.214TrpHis: 0.214 ± 0.017
0.59TrpIle: 0.59 ± 0.032
0.426TrpLys: 0.426 ± 0.03
1.625TrpLeu: 1.625 ± 0.064
0.256TrpMet: 0.256 ± 0.021
0.398TrpAsn: 0.398 ± 0.024
0.39TrpPro: 0.39 ± 0.027
0.966TrpGln: 0.966 ± 0.057
0.612TrpArg: 0.612 ± 0.036
0.608TrpSer: 0.608 ± 0.035
0.638TrpThr: 0.638 ± 0.039
0.687TrpVal: 0.687 ± 0.039
0.171TrpTrp: 0.171 ± 0.019
0.4TrpTyr: 0.4 ± 0.03
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.683TyrAla: 2.683 ± 0.066
0.32TyrCys: 0.32 ± 0.024
2.339TyrAsp: 2.339 ± 0.083
2.321TyrGlu: 2.321 ± 0.068
1.724TyrPhe: 1.724 ± 0.055
2.548TyrGly: 2.548 ± 0.073
0.956TyrHis: 0.956 ± 0.045
1.939TyrIle: 1.939 ± 0.061
1.571TyrLys: 1.571 ± 0.056
4.489TyrLeu: 4.489 ± 0.102
0.758TyrMet: 0.758 ± 0.041
1.391TyrAsn: 1.391 ± 0.053
1.559TyrPro: 1.559 ± 0.061
2.806TyrGln: 2.806 ± 0.078
2.013TyrArg: 2.013 ± 0.068
1.941TyrSer: 1.941 ± 0.067
1.866TyrThr: 1.866 ± 0.091
2.443TyrVal: 2.443 ± 0.071
0.424TyrTrp: 0.424 ± 0.029
1.722TyrTyr: 1.722 ± 0.061
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1943 proteins (613071 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski