Amino acid dipepetide frequency for Candidatus Glomeribacter gigasporarum BEG34

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.412AlaAla: 15.412 ± 0.306	1.644AlaCys: 1.644 ± 0.071	5.437AlaAsp: 5.437 ± 0.122	5.889AlaGlu: 5.889 ± 0.142	4.319AlaPhe: 4.319 ± 0.119	8.371AlaGly: 8.371 ± 0.176	3.737AlaHis: 3.737 ± 0.105	5.814AlaIle: 5.814 ± 0.149	3.514AlaLys: 3.514 ± 0.107	16.665AlaLeu: 16.665 ± 0.282	2.752AlaMet: 2.752 ± 0.088	2.724AlaAsn: 2.724 ± 0.092	6.094AlaPro: 6.094 ± 0.16	7.328AlaGln: 7.328 ± 0.143	10.569AlaArg: 10.569 ± 0.254	5.963AlaSer: 5.963 ± 0.121	4.128AlaThr: 4.128 ± 0.102	7.176AlaVal: 7.176 ± 0.14	1.553AlaTrp: 1.553 ± 0.074	3.025AlaTyr: 3.025 ± 0.09	0.009AlaXaa: 0.009 ± 0.004
Cys	2.023CysAla: 2.023 ± 0.088	0.137CysCys: 0.137 ± 0.02	0.519CysAsp: 0.519 ± 0.031	0.615CysGlu: 0.615 ± 0.036	0.459CysPhe: 0.459 ± 0.032	1.085CysGly: 1.085 ± 0.063	0.305CysHis: 0.305 ± 0.026	0.664CysIle: 0.664 ± 0.042	0.368CysLys: 0.368 ± 0.029	1.118CysLeu: 1.118 ± 0.059	0.265CysMet: 0.265 ± 0.026	0.345CysAsn: 0.345 ± 0.025	0.58CysPro: 0.58 ± 0.041	0.431CysGln: 0.431 ± 0.028	0.706CysArg: 0.706 ± 0.04	0.678CysSer: 0.678 ± 0.042	0.647CysThr: 0.647 ± 0.036	0.82CysVal: 0.82 ± 0.047	0.151CysTrp: 0.151 ± 0.02	0.277CysTyr: 0.277 ± 0.025	0.0CysXaa: 0.0 ± 0.0
Asp	7.055AspAla: 7.055 ± 0.142	0.64AspCys: 0.64 ± 0.045	2.24AspAsp: 2.24 ± 0.08	2.992AspGlu: 2.992 ± 0.098	2.182AspPhe: 2.182 ± 0.064	3.276AspGly: 3.276 ± 0.103	1.055AspHis: 1.055 ± 0.045	2.959AspIle: 2.959 ± 0.086	1.784AspLys: 1.784 ± 0.073	4.869AspLeu: 4.869 ± 0.122	1.015AspMet: 1.015 ± 0.057	1.043AspAsn: 1.043 ± 0.055	2.41AspPro: 2.41 ± 0.085	1.94AspGln: 1.94 ± 0.073	2.873AspArg: 2.873 ± 0.092	2.033AspSer: 2.033 ± 0.078	2.694AspThr: 2.694 ± 0.084	3.106AspVal: 3.106 ± 0.081	1.048AspTrp: 1.048 ± 0.056	1.409AspTyr: 1.409 ± 0.062	0.002AspXaa: 0.002 ± 0.002
Glu	6.606GluAla: 6.606 ± 0.159	0.598GluCys: 0.598 ± 0.039	2.172GluAsp: 2.172 ± 0.077	2.64GluGlu: 2.64 ± 0.105	1.777GluPhe: 1.777 ± 0.056	3.264GluGly: 3.264 ± 0.095	1.439GluHis: 1.439 ± 0.057	3.739GluIle: 3.739 ± 0.121	2.596GluLys: 2.596 ± 0.096	4.918GluLeu: 4.918 ± 0.123	1.625GluMet: 1.625 ± 0.059	1.77GluAsn: 1.77 ± 0.079	2.142GluPro: 2.142 ± 0.077	2.869GluGln: 2.869 ± 0.097	5.004GluArg: 5.004 ± 0.119	2.603GluSer: 2.603 ± 0.089	2.978GluThr: 2.978 ± 0.096	3.23GluVal: 3.23 ± 0.096	0.745GluTrp: 0.745 ± 0.039	1.586GluTyr: 1.586 ± 0.06	0.0GluXaa: 0.0 ± 0.0
Phe	4.021PheAla: 4.021 ± 0.129	0.449PheCys: 0.449 ± 0.031	2.519PheAsp: 2.519 ± 0.074	2.55PheGlu: 2.55 ± 0.085	1.576PhePhe: 1.576 ± 0.067	2.985PheGly: 2.985 ± 0.095	0.81PheHis: 0.81 ± 0.039	2.054PheIle: 2.054 ± 0.07	1.628PheLys: 1.628 ± 0.067	3.197PheLeu: 3.197 ± 0.106	0.852PheMet: 0.852 ± 0.045	1.495PheAsn: 1.495 ± 0.064	1.523PhePro: 1.523 ± 0.054	1.257PheGln: 1.257 ± 0.052	1.921PheArg: 1.921 ± 0.075	3.006PheSer: 3.006 ± 0.093	1.923PheThr: 1.923 ± 0.075	2.172PheVal: 2.172 ± 0.076	0.543PheTrp: 0.543 ± 0.039	1.045PheTyr: 1.045 ± 0.055	0.0PheXaa: 0.0 ± 0.0
Gly	8.671GlyAla: 8.671 ± 0.186	0.922GlyCys: 0.922 ± 0.05	2.987GlyAsp: 2.987 ± 0.084	3.865GlyGlu: 3.865 ± 0.104	2.976GlyPhe: 2.976 ± 0.096	5.036GlyGly: 5.036 ± 0.143	1.784GlyHis: 1.784 ± 0.07	4.508GlyIle: 4.508 ± 0.111	3.167GlyLys: 3.167 ± 0.097	7.139GlyLeu: 7.139 ± 0.14	1.767GlyMet: 1.767 ± 0.068	1.919GlyAsn: 1.919 ± 0.081	2.156GlyPro: 2.156 ± 0.079	2.906GlyGln: 2.906 ± 0.091	4.955GlyArg: 4.955 ± 0.122	3.465GlySer: 3.465 ± 0.107	3.087GlyThr: 3.087 ± 0.102	4.82GlyVal: 4.82 ± 0.112	1.132GlyTrp: 1.132 ± 0.054	2.2GlyTyr: 2.2 ± 0.077	0.0GlyXaa: 0.0 ± 0.0
His	3.297HisAla: 3.297 ± 0.1	0.431HisCys: 0.431 ± 0.034	1.059HisAsp: 1.059 ± 0.047	1.136HisGlu: 1.136 ± 0.049	1.232HisPhe: 1.232 ± 0.063	1.821HisGly: 1.821 ± 0.064	0.75HisHis: 0.75 ± 0.048	1.423HisIle: 1.423 ± 0.06	0.824HisLys: 0.824 ± 0.041	2.734HisLeu: 2.734 ± 0.073	0.498HisMet: 0.498 ± 0.034	0.573HisAsn: 0.573 ± 0.033	1.788HisPro: 1.788 ± 0.066	1.018HisGln: 1.018 ± 0.053	1.798HisArg: 1.798 ± 0.061	1.29HisSer: 1.29 ± 0.051	1.409HisThr: 1.409 ± 0.059	1.427HisVal: 1.427 ± 0.052	0.44HisTrp: 0.44 ± 0.031	0.917HisTyr: 0.917 ± 0.043	0.0HisXaa: 0.0 ± 0.0
Ile	7.593IleAla: 7.593 ± 0.171	0.629IleCys: 0.629 ± 0.045	3.616IleAsp: 3.616 ± 0.097	4.119IleGlu: 4.119 ± 0.106	1.923IlePhe: 1.923 ± 0.086	4.629IleGly: 4.629 ± 0.138	1.504IleHis: 1.504 ± 0.06	2.342IleIle: 2.342 ± 0.087	2.044IleLys: 2.044 ± 0.073	4.806IleLeu: 4.806 ± 0.115	0.924IleMet: 0.924 ± 0.055	1.579IleAsn: 1.579 ± 0.061	2.687IlePro: 2.687 ± 0.079	2.606IleGln: 2.606 ± 0.082	3.732IleArg: 3.732 ± 0.107	3.288IleSer: 3.288 ± 0.101	2.582IleThr: 2.582 ± 0.095	3.784IleVal: 3.784 ± 0.113	0.65IleTrp: 0.65 ± 0.041	1.213IleTyr: 1.213 ± 0.061	0.002IleXaa: 0.002 ± 0.002
Lys	4.319LysAla: 4.319 ± 0.122	0.31LysCys: 0.31 ± 0.027	1.693LysAsp: 1.693 ± 0.072	2.098LysGlu: 2.098 ± 0.088	1.062LysPhe: 1.062 ± 0.061	2.417LysGly: 2.417 ± 0.089	0.85LysHis: 0.85 ± 0.049	2.312LysIle: 2.312 ± 0.085	1.905LysLys: 1.905 ± 0.087	3.609LysLeu: 3.609 ± 0.105	1.052LysMet: 1.052 ± 0.049	1.481LysAsn: 1.481 ± 0.064	2.247LysPro: 2.247 ± 0.085	1.793LysGln: 1.793 ± 0.066	3.125LysArg: 3.125 ± 0.096	2.156LysSer: 2.156 ± 0.08	2.559LysThr: 2.559 ± 0.084	2.047LysVal: 2.047 ± 0.073	0.503LysTrp: 0.503 ± 0.033	0.976LysTyr: 0.976 ± 0.051	0.0LysXaa: 0.0 ± 0.0
Leu	12.48LeuAla: 12.48 ± 0.216	1.453LeuCys: 1.453 ± 0.061	5.809LeuAsp: 5.809 ± 0.12	5.821LeuGlu: 5.821 ± 0.137	3.937LeuPhe: 3.937 ± 0.107	6.953LeuGly: 6.953 ± 0.154	2.701LeuHis: 2.701 ± 0.072	6.082LeuIle: 6.082 ± 0.138	5.083LeuLys: 5.083 ± 0.143	10.359LeuLeu: 10.359 ± 0.226	2.685LeuMet: 2.685 ± 0.08	3.9LeuAsn: 3.9 ± 0.099	5.844LeuPro: 5.844 ± 0.13	3.826LeuGln: 3.826 ± 0.102	7.535LeuArg: 7.535 ± 0.163	7.404LeuSer: 7.404 ± 0.153	5.637LeuThr: 5.637 ± 0.124	5.195LeuVal: 5.195 ± 0.119	1.281LeuTrp: 1.281 ± 0.051	2.636LeuTyr: 2.636 ± 0.089	0.005LeuXaa: 0.005 ± 0.003
Met	2.424MetAla: 2.424 ± 0.08	0.226MetCys: 0.226 ± 0.024	1.076MetAsp: 1.076 ± 0.053	1.025MetGlu: 1.025 ± 0.05	0.605MetPhe: 0.605 ± 0.035	1.481MetGly: 1.481 ± 0.067	0.584MetHis: 0.584 ± 0.037	1.362MetIle: 1.362 ± 0.066	1.106MetLys: 1.106 ± 0.058	2.608MetLeu: 2.608 ± 0.073	0.712MetMet: 0.712 ± 0.05	1.106MetAsn: 1.106 ± 0.049	1.546MetPro: 1.546 ± 0.065	1.192MetGln: 1.192 ± 0.055	2.217MetArg: 2.217 ± 0.09	1.483MetSer: 1.483 ± 0.066	1.488MetThr: 1.488 ± 0.058	1.215MetVal: 1.215 ± 0.053	0.163MetTrp: 0.163 ± 0.021	0.359MetTyr: 0.359 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	4.121AsnAla: 4.121 ± 0.118	0.326AsnCys: 0.326 ± 0.035	1.488AsnAsp: 1.488 ± 0.059	1.469AsnGlu: 1.469 ± 0.073	0.966AsnPhe: 0.966 ± 0.049	2.431AsnGly: 2.431 ± 0.082	0.71AsnHis: 0.71 ± 0.041	1.816AsnIle: 1.816 ± 0.07	1.034AsnLys: 1.034 ± 0.055	2.827AsnLeu: 2.827 ± 0.079	0.687AsnMet: 0.687 ± 0.044	0.759AsnAsn: 0.759 ± 0.06	2.124AsnPro: 2.124 ± 0.069	1.26AsnGln: 1.26 ± 0.054	2.137AsnArg: 2.137 ± 0.081	1.227AsnSer: 1.227 ± 0.066	1.881AsnThr: 1.881 ± 0.074	1.751AsnVal: 1.751 ± 0.081	0.382AsnTrp: 0.382 ± 0.035	0.582AsnTyr: 0.582 ± 0.033	0.002AsnXaa: 0.002 ± 0.003
Pro	5.9ProAla: 5.9 ± 0.148	0.515ProCys: 0.515 ± 0.033	3.244ProAsp: 3.244 ± 0.093	3.483ProGlu: 3.483 ± 0.106	2.007ProPhe: 2.007 ± 0.067	3.232ProGly: 3.232 ± 0.096	1.288ProHis: 1.288 ± 0.054	2.196ProIle: 2.196 ± 0.067	1.667ProLys: 1.667 ± 0.063	5.192ProLeu: 5.192 ± 0.122	0.952ProMet: 0.952 ± 0.051	1.579ProAsn: 1.579 ± 0.06	2.429ProPro: 2.429 ± 0.093	1.737ProGln: 1.737 ± 0.059	2.941ProArg: 2.941 ± 0.085	2.906ProSer: 2.906 ± 0.084	1.944ProThr: 1.944 ± 0.072	4.012ProVal: 4.012 ± 0.101	0.577ProTrp: 0.577 ± 0.035	1.406ProTyr: 1.406 ± 0.063	0.005ProXaa: 0.005 ± 0.003
Gln	5.372GlnAla: 5.372 ± 0.132	0.517GlnCys: 0.517 ± 0.036	1.676GlnAsp: 1.676 ± 0.068	1.898GlnGlu: 1.898 ± 0.072	1.362GlnPhe: 1.362 ± 0.055	2.72GlnGly: 2.72 ± 0.076	1.127GlnHis: 1.127 ± 0.05	2.748GlnIle: 2.748 ± 0.08	1.942GlnLys: 1.942 ± 0.076	4.806GlnLeu: 4.806 ± 0.112	1.204GlnMet: 1.204 ± 0.049	1.462GlnAsn: 1.462 ± 0.069	2.298GlnPro: 2.298 ± 0.075	2.389GlnGln: 2.389 ± 0.096	4.124GlnArg: 4.124 ± 0.104	2.668GlnSer: 2.668 ± 0.077	2.757GlnThr: 2.757 ± 0.08	2.468GlnVal: 2.468 ± 0.084	0.822GlnTrp: 0.822 ± 0.045	1.236GlnTyr: 1.236 ± 0.051	0.0GlnXaa: 0.0 ± 0.0
Arg	10.443ArgAla: 10.443 ± 0.269	0.936ArgCys: 0.936 ± 0.051	3.288ArgAsp: 3.288 ± 0.098	3.588ArgGlu: 3.588 ± 0.09	3.23ArgPhe: 3.23 ± 0.094	4.312ArgGly: 4.312 ± 0.121	1.884ArgHis: 1.884 ± 0.076	4.794ArgIle: 4.794 ± 0.112	2.545ArgLys: 2.545 ± 0.082	8.252ArgLeu: 8.252 ± 0.165	2.021ArgMet: 2.021 ± 0.079	2.196ArgAsn: 2.196 ± 0.077	2.952ArgPro: 2.952 ± 0.097	3.244ArgGln: 3.244 ± 0.092	5.842ArgArg: 5.842 ± 0.14	3.511ArgSer: 3.511 ± 0.092	3.253ArgThr: 3.253 ± 0.089	4.603ArgVal: 4.603 ± 0.108	1.164ArgTrp: 1.164 ± 0.055	2.261ArgTyr: 2.261 ± 0.082	0.002ArgXaa: 0.002 ± 0.002
Ser	7.307SerAla: 7.307 ± 0.14	0.561SerCys: 0.561 ± 0.039	2.741SerAsp: 2.741 ± 0.075	3.039SerGlu: 3.039 ± 0.085	2.002SerPhe: 2.002 ± 0.077	5.071SerGly: 5.071 ± 0.13	1.222SerHis: 1.222 ± 0.059	3.185SerIle: 3.185 ± 0.081	2.093SerLys: 2.093 ± 0.07	5.26SerLeu: 5.26 ± 0.12	1.36SerMet: 1.36 ± 0.057	1.665SerAsn: 1.665 ± 0.073	2.454SerPro: 2.454 ± 0.087	2.063SerGln: 2.063 ± 0.075	3.467SerArg: 3.467 ± 0.093	3.181SerSer: 3.181 ± 0.108	2.408SerThr: 2.408 ± 0.077	3.893SerVal: 3.893 ± 0.118	0.57SerTrp: 0.57 ± 0.039	1.341SerTyr: 1.341 ± 0.063	0.005SerXaa: 0.005 ± 0.003
Thr	5.272ThrAla: 5.272 ± 0.115	0.452ThrCys: 0.452 ± 0.039	2.429ThrAsp: 2.429 ± 0.084	2.557ThrGlu: 2.557 ± 0.093	1.597ThrPhe: 1.597 ± 0.06	3.926ThrGly: 3.926 ± 0.099	1.553ThrHis: 1.553 ± 0.063	2.282ThrIle: 2.282 ± 0.073	1.302ThrLys: 1.302 ± 0.064	6.885ThrLeu: 6.885 ± 0.159	0.983ThrMet: 0.983 ± 0.048	1.066ThrAsn: 1.066 ± 0.052	3.22ThrPro: 3.22 ± 0.095	2.429ThrGln: 2.429 ± 0.087	3.188ThrArg: 3.188 ± 0.095	2.228ThrSer: 2.228 ± 0.073	2.2ThrThr: 2.2 ± 0.091	3.814ThrVal: 3.814 ± 0.101	0.454ThrTrp: 0.454 ± 0.033	1.022ThrTyr: 1.022 ± 0.058	0.002ThrXaa: 0.002 ± 0.002
Val	5.809ValAla: 5.809 ± 0.128	0.885ValCys: 0.885 ± 0.049	2.983ValAsp: 2.983 ± 0.094	3.681ValGlu: 3.681 ± 0.113	2.694ValPhe: 2.694 ± 0.076	3.518ValGly: 3.518 ± 0.096	1.586ValHis: 1.586 ± 0.057	3.695ValIle: 3.695 ± 0.103	2.543ValLys: 2.543 ± 0.08	6.599ValLeu: 6.599 ± 0.128	1.681ValMet: 1.681 ± 0.077	2.205ValAsn: 2.205 ± 0.085	2.638ValPro: 2.638 ± 0.089	3.078ValGln: 3.078 ± 0.103	4.825ValArg: 4.825 ± 0.108	3.772ValSer: 3.772 ± 0.093	3.053ValThr: 3.053 ± 0.102	3.937ValVal: 3.937 ± 0.105	0.943ValTrp: 0.943 ± 0.042	1.667ValTyr: 1.667 ± 0.059	0.002ValXaa: 0.002 ± 0.002
Trp	0.943TrpAla: 0.943 ± 0.048	0.175TrpCys: 0.175 ± 0.02	0.48TrpAsp: 0.48 ± 0.032	0.526TrpGlu: 0.526 ± 0.039	0.536TrpPhe: 0.536 ± 0.039	0.81TrpGly: 0.81 ± 0.043	0.407TrpHis: 0.407 ± 0.031	1.013TrpIle: 1.013 ± 0.051	0.64TrpLys: 0.64 ± 0.047	1.856TrpLeu: 1.856 ± 0.078	0.515TrpMet: 0.515 ± 0.041	0.442TrpAsn: 0.442 ± 0.036	0.652TrpPro: 0.652 ± 0.043	0.817TrpGln: 0.817 ± 0.049	1.246TrpArg: 1.246 ± 0.06	0.696TrpSer: 0.696 ± 0.044	0.708TrpThr: 0.708 ± 0.042	0.792TrpVal: 0.792 ± 0.041	0.147TrpTrp: 0.147 ± 0.018	0.286TrpTyr: 0.286 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.046TyrAla: 3.046 ± 0.081	0.387TyrCys: 0.387 ± 0.028	1.167TyrAsp: 1.167 ± 0.053	1.306TyrGlu: 1.306 ± 0.06	1.085TyrPhe: 1.085 ± 0.05	2.121TyrGly: 2.121 ± 0.073	0.566TyrHis: 0.566 ± 0.034	1.262TyrIle: 1.262 ± 0.049	0.726TyrLys: 0.726 ± 0.045	2.931TyrLeu: 2.931 ± 0.09	0.424TyrMet: 0.424 ± 0.031	0.673TyrAsn: 0.673 ± 0.039	1.427TyrPro: 1.427 ± 0.06	1.413TyrGln: 1.413 ± 0.053	2.117TyrArg: 2.117 ± 0.078	1.327TyrSer: 1.327 ± 0.06	1.523TyrThr: 1.523 ± 0.063	1.527TyrVal: 1.527 ± 0.058	0.419TyrTrp: 0.419 ± 0.024	0.715TyrTyr: 0.715 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.007XaaAla: 0.007 ± 0.005	0.0XaaCys: 0.0 ± 0.0	0.002XaaAsp: 0.002 ± 0.002	0.005XaaGlu: 0.005 ± 0.003	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.002	0.002XaaHis: 0.002 ± 0.002	0.002XaaIle: 0.002 ± 0.002	0.002XaaLys: 0.002 ± 0.003	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.002XaaGln: 0.002 ± 0.002	0.002XaaArg: 0.002 ± 0.002	0.002XaaSer: 0.002 ± 0.002	0.0XaaThr: 0.0 ± 0.0	0.005XaaVal: 0.005 ± 0.003	0.0XaaTrp: 0.0 ± 0.0	0.002XaaTyr: 0.002 ± 0.003	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 1471 proteins (429475 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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