Amino acid dipepetide frequency for Dethiosulfatibacter aminovorans DSM 17477

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.52AlaAla: 5.52 ± 0.096	0.852AlaCys: 0.852 ± 0.028	3.486AlaAsp: 3.486 ± 0.062	4.554AlaGlu: 4.554 ± 0.066	2.837AlaPhe: 2.837 ± 0.055	5.401AlaGly: 5.401 ± 0.083	0.922AlaHis: 0.922 ± 0.029	5.604AlaIle: 5.604 ± 0.083	4.037AlaLys: 4.037 ± 0.063	6.105AlaLeu: 6.105 ± 0.079	2.269AlaMet: 2.269 ± 0.047	2.361AlaAsn: 2.361 ± 0.046	1.613AlaPro: 1.613 ± 0.045	1.407AlaGln: 1.407 ± 0.036	2.458AlaArg: 2.458 ± 0.048	3.773AlaSer: 3.773 ± 0.06	3.063AlaThr: 3.063 ± 0.061	5.702AlaVal: 5.702 ± 0.079	0.409AlaTrp: 0.409 ± 0.022	2.377AlaTyr: 2.377 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	0.718CysAla: 0.718 ± 0.026	0.167CysCys: 0.167 ± 0.012	0.729CysAsp: 0.729 ± 0.024	0.71CysGlu: 0.71 ± 0.024	0.486CysPhe: 0.486 ± 0.021	1.189CysGly: 1.189 ± 0.035	0.224CysHis: 0.224 ± 0.014	1.046CysIle: 1.046 ± 0.033	0.699CysLys: 0.699 ± 0.027	0.914CysLeu: 0.914 ± 0.029	0.331CysMet: 0.331 ± 0.017	0.514CysAsn: 0.514 ± 0.022	0.55CysPro: 0.55 ± 0.026	0.283CysGln: 0.283 ± 0.016	0.535CysArg: 0.535 ± 0.021	0.829CysSer: 0.829 ± 0.028	0.628CysThr: 0.628 ± 0.025	0.684CysVal: 0.684 ± 0.028	0.068CysTrp: 0.068 ± 0.007	0.38CysTyr: 0.38 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.442AspAla: 3.442 ± 0.051	0.657AspCys: 0.657 ± 0.026	3.384AspAsp: 3.384 ± 0.079	5.367AspGlu: 5.367 ± 0.065	2.77AspPhe: 2.77 ± 0.047	3.921AspGly: 3.921 ± 0.072	0.818AspHis: 0.818 ± 0.03	6.131AspIle: 6.131 ± 0.077	4.44AspLys: 4.44 ± 0.067	5.201AspLeu: 5.201 ± 0.074	2.09AspMet: 2.09 ± 0.046	2.837AspAsn: 2.837 ± 0.054	1.584AspPro: 1.584 ± 0.037	1.019AspGln: 1.019 ± 0.03	2.49AspArg: 2.49 ± 0.046	3.572AspSer: 3.572 ± 0.069	2.668AspThr: 2.668 ± 0.049	4.135AspVal: 4.135 ± 0.067	0.447AspTrp: 0.447 ± 0.02	2.849AspTyr: 2.849 ± 0.061	0.0AspXaa: 0.0 ± 0.0
Glu	4.823GluAla: 4.823 ± 0.073	0.689GluCys: 0.689 ± 0.029	4.78GluAsp: 4.78 ± 0.07	7.013GluGlu: 7.013 ± 0.104	3.143GluPhe: 3.143 ± 0.056	4.892GluGly: 4.892 ± 0.066	1.077GluHis: 1.077 ± 0.03	7.377GluIle: 7.377 ± 0.1	7.451GluLys: 7.451 ± 0.101	6.766GluLeu: 6.766 ± 0.075	2.731GluMet: 2.731 ± 0.047	4.811GluAsn: 4.811 ± 0.075	1.631GluPro: 1.631 ± 0.043	1.613GluGln: 1.613 ± 0.04	3.166GluArg: 3.166 ± 0.059	4.089GluSer: 4.089 ± 0.062	3.501GluThr: 3.501 ± 0.062	4.824GluVal: 4.824 ± 0.064	0.5GluTrp: 0.5 ± 0.021	3.381GluTyr: 3.381 ± 0.052	0.0GluXaa: 0.0 ± 0.0
Phe	2.704PheAla: 2.704 ± 0.051	0.518PheCys: 0.518 ± 0.023	2.817PheAsp: 2.817 ± 0.055	3.052PheGlu: 3.052 ± 0.058	1.925PhePhe: 1.925 ± 0.043	3.393PheGly: 3.393 ± 0.05	0.662PheHis: 0.662 ± 0.024	3.891PheIle: 3.891 ± 0.066	2.9PheLys: 2.9 ± 0.052	3.679PheLeu: 3.679 ± 0.061	1.391PheMet: 1.391 ± 0.04	2.248PheAsn: 2.248 ± 0.046	1.235PhePro: 1.235 ± 0.031	0.799PheGln: 0.799 ± 0.028	1.551PheArg: 1.551 ± 0.034	3.105PheSer: 3.105 ± 0.057	2.293PheThr: 2.293 ± 0.05	2.921PheVal: 2.921 ± 0.051	0.354PheTrp: 0.354 ± 0.018	1.606PheTyr: 1.606 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	5.05GlyAla: 5.05 ± 0.085	1.112GlyCys: 1.112 ± 0.033	3.622GlyAsp: 3.622 ± 0.063	4.671GlyGlu: 4.671 ± 0.061	3.46GlyPhe: 3.46 ± 0.062	5.259GlyGly: 5.259 ± 0.083	1.2GlyHis: 1.2 ± 0.03	7.138GlyIle: 7.138 ± 0.082	5.522GlyLys: 5.522 ± 0.079	6.502GlyLeu: 6.502 ± 0.088	2.566GlyMet: 2.566 ± 0.048	3.28GlyAsn: 3.28 ± 0.058	1.678GlyPro: 1.678 ± 0.041	1.583GlyGln: 1.583 ± 0.038	2.961GlyArg: 2.961 ± 0.052	4.235GlySer: 4.235 ± 0.059	4.094GlyThr: 4.094 ± 0.06	5.138GlyVal: 5.138 ± 0.076	0.623GlyTrp: 0.623 ± 0.026	3.245GlyTyr: 3.245 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	0.844HisAla: 0.844 ± 0.03	0.224HisCys: 0.224 ± 0.013	0.894HisAsp: 0.894 ± 0.029	1.055HisGlu: 1.055 ± 0.031	0.696HisPhe: 0.696 ± 0.021	1.182HisGly: 1.182 ± 0.034	0.303HisHis: 0.303 ± 0.016	1.32HisIle: 1.32 ± 0.039	0.932HisLys: 0.932 ± 0.033	1.274HisLeu: 1.274 ± 0.034	0.509HisMet: 0.509 ± 0.021	0.729HisAsn: 0.729 ± 0.027	0.744HisPro: 0.744 ± 0.027	0.338HisGln: 0.338 ± 0.014	0.642HisArg: 0.642 ± 0.021	0.936HisSer: 0.936 ± 0.031	0.761HisThr: 0.761 ± 0.026	1.065HisVal: 1.065 ± 0.032	0.14HisTrp: 0.14 ± 0.011	0.701HisTyr: 0.701 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.06IleAla: 6.06 ± 0.077	1.064IleCys: 1.064 ± 0.033	5.764IleAsp: 5.764 ± 0.071	7.047IleGlu: 7.047 ± 0.085	3.781IlePhe: 3.781 ± 0.059	6.554IleGly: 6.554 ± 0.081	1.36IleHis: 1.36 ± 0.034	7.801IleIle: 7.801 ± 0.1	6.131IleLys: 6.131 ± 0.072	7.738IleLeu: 7.738 ± 0.087	2.745IleMet: 2.745 ± 0.045	4.562IleAsn: 4.562 ± 0.07	3.366IlePro: 3.366 ± 0.063	1.924IleGln: 1.924 ± 0.033	3.6IleArg: 3.6 ± 0.056	6.032IleSer: 6.032 ± 0.082	4.457IleThr: 4.457 ± 0.071	6.235IleVal: 6.235 ± 0.088	0.51IleTrp: 0.51 ± 0.023	3.065IleTyr: 3.065 ± 0.052	0.0IleXaa: 0.0 ± 0.0
Lys	4.448LysAla: 4.448 ± 0.058	0.741LysCys: 0.741 ± 0.027	4.632LysAsp: 4.632 ± 0.06	6.463LysGlu: 6.463 ± 0.081	2.488LysPhe: 2.488 ± 0.045	4.973LysGly: 4.973 ± 0.067	1.117LysHis: 1.117 ± 0.034	6.445LysIle: 6.445 ± 0.075	6.565LysLys: 6.565 ± 0.096	6.031LysLeu: 6.031 ± 0.067	2.37LysMet: 2.37 ± 0.045	4.293LysAsn: 4.293 ± 0.059	2.064LysPro: 2.064 ± 0.045	1.568LysGln: 1.568 ± 0.033	3.028LysArg: 3.028 ± 0.058	4.436LysSer: 4.436 ± 0.066	3.779LysThr: 3.779 ± 0.056	4.849LysVal: 4.849 ± 0.076	0.564LysTrp: 0.564 ± 0.023	3.298LysTyr: 3.298 ± 0.06	0.0LysXaa: 0.0 ± 0.0
Leu	6.032LeuAla: 6.032 ± 0.078	0.903LeuCys: 0.903 ± 0.026	5.42LeuAsp: 5.42 ± 0.07	6.965LeuGlu: 6.965 ± 0.09	3.717LeuPhe: 3.717 ± 0.063	6.515LeuGly: 6.515 ± 0.092	1.238LeuHis: 1.238 ± 0.034	6.971LeuIle: 6.971 ± 0.079	6.887LeuLys: 6.887 ± 0.084	7.541LeuLeu: 7.541 ± 0.082	2.791LeuMet: 2.791 ± 0.053	4.465LeuAsn: 4.465 ± 0.061	3.073LeuPro: 3.073 ± 0.058	1.851LeuGln: 1.851 ± 0.042	3.253LeuArg: 3.253 ± 0.055	6.074LeuSer: 6.074 ± 0.078	4.277LeuThr: 4.277 ± 0.069	6.167LeuVal: 6.167 ± 0.079	0.524LeuTrp: 0.524 ± 0.024	2.972LeuTyr: 2.972 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.403MetAla: 2.403 ± 0.053	0.289MetCys: 0.289 ± 0.016	2.276MetAsp: 2.276 ± 0.041	2.688MetGlu: 2.688 ± 0.051	1.212MetPhe: 1.212 ± 0.034	2.357MetGly: 2.357 ± 0.046	0.437MetHis: 0.437 ± 0.02	2.68MetIle: 2.68 ± 0.048	2.93MetLys: 2.93 ± 0.049	2.698MetLeu: 2.698 ± 0.051	1.002MetMet: 1.002 ± 0.032	1.955MetAsn: 1.955 ± 0.04	1.061MetPro: 1.061 ± 0.029	0.646MetGln: 0.646 ± 0.023	1.11MetArg: 1.11 ± 0.031	2.082MetSer: 2.082 ± 0.041	1.761MetThr: 1.761 ± 0.045	2.18MetVal: 2.18 ± 0.048	0.156MetTrp: 0.156 ± 0.01	0.942MetTyr: 0.942 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	2.749AsnAla: 2.749 ± 0.045	0.708AsnCys: 0.708 ± 0.025	2.722AsnAsp: 2.722 ± 0.051	3.709AsnGlu: 3.709 ± 0.059	1.864AsnPhe: 1.864 ± 0.041	3.208AsnGly: 3.208 ± 0.06	0.843AsnHis: 0.843 ± 0.028	5.278AsnIle: 5.278 ± 0.075	3.649AsnLys: 3.649 ± 0.052	4.429AsnLeu: 4.429 ± 0.064	1.661AsnMet: 1.661 ± 0.037	2.527AsnAsn: 2.527 ± 0.047	2.11AsnPro: 2.11 ± 0.044	1.107AsnGln: 1.107 ± 0.032	2.244AsnArg: 2.244 ± 0.042	3.003AsnSer: 3.003 ± 0.047	2.471AsnThr: 2.471 ± 0.049	3.136AsnVal: 3.136 ± 0.055	0.389AsnTrp: 0.389 ± 0.017	1.963AsnTyr: 1.963 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	1.948ProAla: 1.948 ± 0.047	0.36ProCys: 0.36 ± 0.017	1.888ProAsp: 1.888 ± 0.036	2.988ProGlu: 2.988 ± 0.057	1.486ProPhe: 1.486 ± 0.034	2.491ProGly: 2.491 ± 0.046	0.565ProHis: 0.565 ± 0.021	2.323ProIle: 2.323 ± 0.048	1.708ProLys: 1.708 ± 0.037	2.745ProLeu: 2.745 ± 0.053	0.899ProMet: 0.899 ± 0.029	1.144ProAsn: 1.144 ± 0.031	0.785ProPro: 0.785 ± 0.026	0.761ProGln: 0.761 ± 0.025	0.967ProArg: 0.967 ± 0.032	1.804ProSer: 1.804 ± 0.047	1.471ProThr: 1.471 ± 0.033	2.957ProVal: 2.957 ± 0.053	0.23ProTrp: 0.23 ± 0.014	1.322ProTyr: 1.322 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	1.43GlnAla: 1.43 ± 0.039	0.242GlnCys: 0.242 ± 0.015	1.066GlnAsp: 1.066 ± 0.032	1.59GlnGlu: 1.59 ± 0.037	0.879GlnPhe: 0.879 ± 0.027	1.398GlnGly: 1.398 ± 0.035	0.337GlnHis: 0.337 ± 0.018	1.929GlnIle: 1.929 ± 0.041	1.66GlnLys: 1.66 ± 0.04	1.958GlnLeu: 1.958 ± 0.043	0.785GlnMet: 0.785 ± 0.028	1.065GlnAsn: 1.065 ± 0.032	0.614GlnPro: 0.614 ± 0.025	0.541GlnGln: 0.541 ± 0.023	0.821GlnArg: 0.821 ± 0.028	1.225GlnSer: 1.225 ± 0.034	1.002GlnThr: 1.002 ± 0.036	1.573GlnVal: 1.573 ± 0.035	0.2GlnTrp: 0.2 ± 0.014	0.921GlnTyr: 0.921 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	2.089ArgAla: 2.089 ± 0.044	0.426ArgCys: 0.426 ± 0.019	2.374ArgAsp: 2.374 ± 0.044	3.54ArgGlu: 3.54 ± 0.055	1.75ArgPhe: 1.75 ± 0.041	2.337ArgGly: 2.337 ± 0.048	0.612ArgHis: 0.612 ± 0.024	3.989ArgIle: 3.989 ± 0.053	3.584ArgLys: 3.584 ± 0.06	3.281ArgLeu: 3.281 ± 0.058	1.403ArgMet: 1.403 ± 0.03	2.208ArgAsn: 2.208 ± 0.044	1.065ArgPro: 1.065 ± 0.033	1.019ArgGln: 1.019 ± 0.03	1.644ArgArg: 1.644 ± 0.053	1.927ArgSer: 1.927 ± 0.038	1.903ArgThr: 1.903 ± 0.037	2.48ArgVal: 2.48 ± 0.047	0.28ArgTrp: 0.28 ± 0.018	1.605ArgTyr: 1.605 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	3.624SerAla: 3.624 ± 0.053	0.735SerCys: 0.735 ± 0.028	3.473SerAsp: 3.473 ± 0.062	4.201SerGlu: 4.201 ± 0.064	2.945SerPhe: 2.945 ± 0.051	4.831SerGly: 4.831 ± 0.076	1.0SerHis: 1.0 ± 0.031	5.915SerIle: 5.915 ± 0.075	4.16SerLys: 4.16 ± 0.062	5.706SerLeu: 5.706 ± 0.083	2.15SerMet: 2.15 ± 0.039	2.794SerAsn: 2.794 ± 0.053	1.846SerPro: 1.846 ± 0.046	1.479SerGln: 1.479 ± 0.036	2.788SerArg: 2.788 ± 0.051	4.103SerSer: 4.103 ± 0.061	2.975SerThr: 2.975 ± 0.056	4.117SerVal: 4.117 ± 0.063	0.476SerTrp: 0.476 ± 0.023	2.494SerTyr: 2.494 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	3.636ThrAla: 3.636 ± 0.069	0.553ThrCys: 0.553 ± 0.023	2.897ThrAsp: 2.897 ± 0.046	3.305ThrGlu: 3.305 ± 0.055	2.069ThrPhe: 2.069 ± 0.045	4.823ThrGly: 4.823 ± 0.071	0.769ThrHis: 0.769 ± 0.025	4.296ThrIle: 4.296 ± 0.064	2.722ThrLys: 2.722 ± 0.043	4.403ThrLeu: 4.403 ± 0.063	1.539ThrMet: 1.539 ± 0.036	2.055ThrAsn: 2.055 ± 0.04	1.864ThrPro: 1.864 ± 0.039	0.931ThrGln: 0.931 ± 0.03	1.846ThrArg: 1.846 ± 0.038	2.963ThrSer: 2.963 ± 0.057	2.601ThrThr: 2.601 ± 0.061	4.2ThrVal: 4.2 ± 0.07	0.373ThrTrp: 0.373 ± 0.021	1.707ThrTyr: 1.707 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	4.573ValAla: 4.573 ± 0.063	0.833ValCys: 0.833 ± 0.028	4.51ValAsp: 4.51 ± 0.069	5.807ValGlu: 5.807 ± 0.089	3.382ValPhe: 3.382 ± 0.057	4.654ValGly: 4.654 ± 0.067	1.046ValHis: 1.046 ± 0.028	5.846ValIle: 5.846 ± 0.072	5.116ValLys: 5.116 ± 0.07	6.558ValLeu: 6.558 ± 0.078	2.205ValMet: 2.205 ± 0.045	3.351ValAsn: 3.351 ± 0.049	2.351ValPro: 2.351 ± 0.045	1.415ValGln: 1.415 ± 0.034	2.428ValArg: 2.428 ± 0.047	4.451ValSer: 4.451 ± 0.063	3.56ValThr: 3.56 ± 0.058	5.364ValVal: 5.364 ± 0.08	0.448ValTrp: 0.448 ± 0.022	2.6ValTyr: 2.6 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.481TrpAla: 0.481 ± 0.024	0.08TrpCys: 0.08 ± 0.009	0.404TrpAsp: 0.404 ± 0.019	0.447TrpGlu: 0.447 ± 0.023	0.343TrpPhe: 0.343 ± 0.017	0.595TrpGly: 0.595 ± 0.025	0.124TrpHis: 0.124 ± 0.009	0.634TrpIle: 0.634 ± 0.026	0.533TrpLys: 0.533 ± 0.022	0.579TrpLeu: 0.579 ± 0.021	0.241TrpMet: 0.241 ± 0.015	0.448TrpAsn: 0.448 ± 0.02	0.239TrpPro: 0.239 ± 0.016	0.16TrpGln: 0.16 ± 0.013	0.24TrpArg: 0.24 ± 0.012	0.39TrpSer: 0.39 ± 0.021	0.378TrpThr: 0.378 ± 0.02	0.407TrpVal: 0.407 ± 0.019	0.092TrpTrp: 0.092 ± 0.009	0.276TrpTyr: 0.276 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.176TyrAla: 2.176 ± 0.045	0.531TyrCys: 0.531 ± 0.022	2.683TyrAsp: 2.683 ± 0.051	3.086TyrGlu: 3.086 ± 0.065	1.811TyrPhe: 1.811 ± 0.041	2.966TyrGly: 2.966 ± 0.052	0.634TyrHis: 0.634 ± 0.023	3.184TyrIle: 3.184 ± 0.057	2.526TyrLys: 2.526 ± 0.049	3.528TyrLeu: 3.528 ± 0.061	1.185TyrMet: 1.185 ± 0.031	2.122TyrAsn: 2.122 ± 0.044	1.371TyrPro: 1.371 ± 0.036	0.791TyrGln: 0.791 ± 0.027	1.744TyrArg: 1.744 ± 0.042	2.787TyrSer: 2.787 ± 0.046	1.907TyrThr: 1.907 ± 0.041	2.364TyrVal: 2.364 ± 0.056	0.307TyrTrp: 0.307 ± 0.017	1.747TyrTyr: 1.747 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3628 proteins (1182095 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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