Amino acid dipepetide frequency for Chilli leaf curl Sri Lanka virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.339AlaAla: 7.339 ± 3.287
0.917AlaCys: 0.917 ± 0.842
2.752AlaAsp: 2.752 ± 1.069
0.917AlaGlu: 0.917 ± 0.643
0.0AlaPhe: 0.0 ± 0.0
1.835AlaGly: 1.835 ± 1.221
2.752AlaHis: 2.752 ± 2.518
3.67AlaIle: 3.67 ± 1.552
3.67AlaLys: 3.67 ± 1.552
7.339AlaLeu: 7.339 ± 2.594
0.0AlaMet: 0.0 ± 0.0
1.835AlaAsn: 1.835 ± 0.835
0.917AlaPro: 0.917 ± 0.643
3.67AlaGln: 3.67 ± 1.836
2.752AlaArg: 2.752 ± 1.928
5.505AlaSer: 5.505 ± 2.099
4.587AlaThr: 4.587 ± 3.262
3.67AlaVal: 3.67 ± 1.789
0.917AlaTrp: 0.917 ± 0.643
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.835CysCys: 1.835 ± 2.274
0.0CysAsp: 0.0 ± 0.0
0.917CysGlu: 0.917 ± 0.842
0.917CysPhe: 0.917 ± 1.042
1.835CysGly: 1.835 ± 1.031
0.0CysHis: 0.0 ± 0.0
2.752CysIle: 2.752 ± 1.507
0.917CysLys: 0.917 ± 0.842
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.917CysAsn: 0.917 ± 0.643
3.67CysPro: 3.67 ± 2.344
0.0CysGln: 0.0 ± 0.0
0.917CysArg: 0.917 ± 1.083
1.835CysSer: 1.835 ± 2.166
0.917CysThr: 0.917 ± 0.842
0.917CysVal: 0.917 ± 0.842
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.752AspAla: 2.752 ± 1.928
0.917AspCys: 0.917 ± 1.083
1.835AspAsp: 1.835 ± 1.031
2.752AspGlu: 2.752 ± 1.23
2.752AspPhe: 2.752 ± 1.23
2.752AspGly: 2.752 ± 1.928
1.835AspHis: 1.835 ± 1.581
0.917AspIle: 0.917 ± 1.124
1.835AspLys: 1.835 ± 0.835
7.339AspLeu: 7.339 ± 3.571
0.917AspMet: 0.917 ± 0.842
1.835AspAsn: 1.835 ± 1.221
2.752AspPro: 2.752 ± 1.408
0.917AspGln: 0.917 ± 0.643
2.752AspArg: 2.752 ± 1.549
3.67AspSer: 3.67 ± 1.195
0.917AspThr: 0.917 ± 1.083
6.422AspVal: 6.422 ± 3.156
2.752AspTrp: 2.752 ± 1.334
0.917AspTyr: 0.917 ± 0.643
0.0AspXaa: 0.0 ± 0.0
Glu
2.752GluAla: 2.752 ± 1.069
0.0GluCys: 0.0 ± 0.0
0.917GluAsp: 0.917 ± 1.124
4.587GluGlu: 4.587 ± 2.537
2.752GluPhe: 2.752 ± 1.928
2.752GluGly: 2.752 ± 1.23
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
3.67GluLys: 3.67 ± 2.57
3.67GluLeu: 3.67 ± 1.649
0.0GluMet: 0.0 ± 0.0
3.67GluAsn: 3.67 ± 2.474
1.835GluPro: 1.835 ± 0.835
1.835GluGln: 1.835 ± 0.835
0.917GluArg: 0.917 ± 1.042
2.752GluSer: 2.752 ± 1.505
0.917GluThr: 0.917 ± 1.124
3.67GluVal: 3.67 ± 1.649
2.752GluTrp: 2.752 ± 0.978
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.835PheAla: 1.835 ± 1.011
0.917PheCys: 0.917 ± 0.842
2.752PheAsp: 2.752 ± 1.23
0.917PheGlu: 0.917 ± 0.842
0.917PhePhe: 0.917 ± 0.842
1.835PheGly: 1.835 ± 0.835
0.917PheHis: 0.917 ± 0.643
1.835PheIle: 1.835 ± 1.285
3.67PheLys: 3.67 ± 1.836
6.422PheLeu: 6.422 ± 1.632
0.917PheMet: 0.917 ± 0.643
3.67PheAsn: 3.67 ± 3.026
0.0PhePro: 0.0 ± 0.0
4.587PheGln: 4.587 ± 2.385
3.67PheArg: 3.67 ± 2.238
2.752PheSer: 2.752 ± 1.408
0.917PheThr: 0.917 ± 1.083
1.835PheVal: 1.835 ± 0.835
0.0PheTrp: 0.0 ± 0.0
1.835PheTyr: 1.835 ± 1.683
0.0PheXaa: 0.0 ± 0.0
Gly
1.835GlyAla: 1.835 ± 1.285
1.835GlyCys: 1.835 ± 1.221
4.587GlyAsp: 4.587 ± 1.539
1.835GlyGlu: 1.835 ± 1.011
0.917GlyPhe: 0.917 ± 1.083
3.67GlyGly: 3.67 ± 1.775
1.835GlyHis: 1.835 ± 1.011
3.67GlyIle: 3.67 ± 1.836
8.257GlyLys: 8.257 ± 3.575
1.835GlyLeu: 1.835 ± 1.237
0.917GlyMet: 0.917 ± 1.137
0.917GlyAsn: 0.917 ± 1.083
8.257GlyPro: 8.257 ± 2.827
2.752GlyGln: 2.752 ± 1.069
1.835GlyArg: 1.835 ± 1.172
2.752GlySer: 2.752 ± 1.928
2.752GlyThr: 2.752 ± 0.978
2.752GlyVal: 2.752 ± 1.867
0.0GlyTrp: 0.0 ± 0.0
0.917GlyTyr: 0.917 ± 1.137
0.0GlyXaa: 0.0 ± 0.0
His
2.752HisAla: 2.752 ± 1.549
1.835HisCys: 1.835 ± 1.57
1.835HisAsp: 1.835 ± 1.162
0.917HisGlu: 0.917 ± 1.137
3.67HisPhe: 3.67 ± 1.592
1.835HisGly: 1.835 ± 2.166
0.917HisHis: 0.917 ± 1.083
2.752HisIle: 2.752 ± 0.978
1.835HisLys: 1.835 ± 1.581
0.917HisLeu: 0.917 ± 0.643
0.0HisMet: 0.0 ± 0.0
2.752HisAsn: 2.752 ± 1.335
3.67HisPro: 3.67 ± 2.296
1.835HisGln: 1.835 ± 1.285
3.67HisArg: 3.67 ± 2.442
1.835HisSer: 1.835 ± 0.835
0.917HisThr: 0.917 ± 0.842
1.835HisVal: 1.835 ± 1.581
0.917HisTrp: 0.917 ± 0.643
1.835HisTyr: 1.835 ± 1.031
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
1.835IleAsp: 1.835 ± 1.285
1.835IleGlu: 1.835 ± 1.285
6.422IlePhe: 6.422 ± 2.893
1.835IleGly: 1.835 ± 0.835
2.752IleHis: 2.752 ± 1.234
2.752IleIle: 2.752 ± 0.929
5.505IleLys: 5.505 ± 1.01
1.835IleLeu: 1.835 ± 2.085
0.0IleMet: 0.0 ± 0.0
2.752IleAsn: 2.752 ± 1.234
1.835IlePro: 1.835 ± 1.285
4.587IleGln: 4.587 ± 2.484
7.339IleArg: 7.339 ± 1.639
7.339IleSer: 7.339 ± 1.894
2.752IleThr: 2.752 ± 2.41
2.752IleVal: 2.752 ± 1.23
1.835IleTrp: 1.835 ± 1.162
0.917IleTyr: 0.917 ± 0.842
0.0IleXaa: 0.0 ± 0.0
Lys
1.835LysAla: 1.835 ± 1.011
2.752LysCys: 2.752 ± 1.95
1.835LysAsp: 1.835 ± 1.285
4.587LysGlu: 4.587 ± 2.001
1.835LysPhe: 1.835 ± 1.162
7.339LysGly: 7.339 ± 1.986
3.67LysHis: 3.67 ± 2.57
2.752LysIle: 2.752 ± 1.741
0.917LysLys: 0.917 ± 0.842
1.835LysLeu: 1.835 ± 1.285
0.917LysMet: 0.917 ± 0.643
4.587LysAsn: 4.587 ± 1.545
4.587LysPro: 4.587 ± 1.497
0.0LysGln: 0.0 ± 0.0
3.67LysArg: 3.67 ± 2.442
4.587LysSer: 4.587 ± 1.539
2.752LysThr: 2.752 ± 1.23
2.752LysVal: 2.752 ± 1.796
0.917LysTrp: 0.917 ± 0.842
3.67LysTyr: 3.67 ± 1.526
0.0LysXaa: 0.0 ± 0.0
Leu
2.752LeuAla: 2.752 ± 1.422
2.752LeuCys: 2.752 ± 1.483
5.505LeuAsp: 5.505 ± 2.668
3.67LeuGlu: 3.67 ± 1.649
0.917LeuPhe: 0.917 ± 0.643
3.67LeuGly: 3.67 ± 1.195
1.835LeuHis: 1.835 ± 1.031
4.587LeuIle: 4.587 ± 2.423
6.422LeuLys: 6.422 ± 1.702
1.835LeuLeu: 1.835 ± 1.237
2.752LeuMet: 2.752 ± 2.209
2.752LeuAsn: 2.752 ± 1.451
1.835LeuPro: 1.835 ± 1.031
5.505LeuGln: 5.505 ± 3.483
3.67LeuArg: 3.67 ± 3.026
2.752LeuSer: 2.752 ± 1.423
8.257LeuThr: 8.257 ± 2.185
2.752LeuVal: 2.752 ± 1.759
1.835LeuTrp: 1.835 ± 1.565
2.752LeuTyr: 2.752 ± 0.929
0.0LeuXaa: 0.0 ± 0.0
Met
0.917MetAla: 0.917 ± 0.842
0.917MetCys: 0.917 ± 0.842
1.835MetAsp: 1.835 ± 1.162
1.835MetGlu: 1.835 ± 1.148
3.67MetPhe: 3.67 ± 2.525
2.752MetGly: 2.752 ± 1.473
0.917MetHis: 0.917 ± 0.842
0.917MetIle: 0.917 ± 0.842
0.0MetLys: 0.0 ± 0.0
3.67MetLeu: 3.67 ± 1.224
0.917MetMet: 0.917 ± 1.124
0.917MetAsn: 0.917 ± 0.842
2.752MetPro: 2.752 ± 2.179
0.917MetGln: 0.917 ± 1.083
0.0MetArg: 0.0 ± 0.0
2.752MetSer: 2.752 ± 2.209
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.917MetTrp: 0.917 ± 0.643
0.917MetTyr: 0.917 ± 0.842
0.0MetXaa: 0.0 ± 0.0
Asn
1.835AsnAla: 1.835 ± 0.835
1.835AsnCys: 1.835 ± 1.031
1.835AsnAsp: 1.835 ± 1.285
1.835AsnGlu: 1.835 ± 1.221
1.835AsnPhe: 1.835 ± 1.011
0.917AsnGly: 0.917 ± 1.042
3.67AsnHis: 3.67 ± 1.809
2.752AsnIle: 2.752 ± 0.929
0.0AsnLys: 0.0 ± 0.0
4.587AsnLeu: 4.587 ± 2.022
2.752AsnMet: 2.752 ± 2.409
2.752AsnAsn: 2.752 ± 2.041
3.67AsnPro: 3.67 ± 1.095
2.752AsnGln: 2.752 ± 1.069
2.752AsnArg: 2.752 ± 1.793
4.587AsnSer: 4.587 ± 1.185
3.67AsnThr: 3.67 ± 1.592
5.505AsnVal: 5.505 ± 3.092
0.0AsnTrp: 0.0 ± 0.0
3.67AsnTyr: 3.67 ± 1.184
0.0AsnXaa: 0.0 ± 0.0
Pro
1.835ProAla: 1.835 ± 1.683
0.917ProCys: 0.917 ± 0.842
4.587ProAsp: 4.587 ± 1.331
0.0ProGlu: 0.0 ± 0.0
1.835ProPhe: 1.835 ± 1.011
0.917ProGly: 0.917 ± 0.643
4.587ProHis: 4.587 ± 2.384
6.422ProIle: 6.422 ± 2.661
5.505ProLys: 5.505 ± 2.076
3.67ProLeu: 3.67 ± 2.357
4.587ProMet: 4.587 ± 1.569
5.505ProAsn: 5.505 ± 1.769
0.917ProPro: 0.917 ± 0.643
4.587ProGln: 4.587 ± 1.852
4.587ProArg: 4.587 ± 1.902
6.422ProSer: 6.422 ± 3.552
2.752ProThr: 2.752 ± 1.473
3.67ProVal: 3.67 ± 1.506
0.0ProTrp: 0.0 ± 0.0
0.917ProTyr: 0.917 ± 0.842
0.0ProXaa: 0.0 ± 0.0
Gln
8.257GlnAla: 8.257 ± 3.17
0.0GlnCys: 0.0 ± 0.0
3.67GlnAsp: 3.67 ± 1.198
3.67GlnGlu: 3.67 ± 1.775
4.587GlnPhe: 4.587 ± 2.405
2.752GlnGly: 2.752 ± 1.334
0.917GlnHis: 0.917 ± 1.083
0.917GlnIle: 0.917 ± 0.643
0.917GlnLys: 0.917 ± 1.137
3.67GlnLeu: 3.67 ± 1.683
2.752GlnMet: 2.752 ± 1.398
0.917GlnAsn: 0.917 ± 1.137
5.505GlnPro: 5.505 ± 4.074
4.587GlnGln: 4.587 ± 1.331
1.835GlnArg: 1.835 ± 1.148
3.67GlnSer: 3.67 ± 0.986
3.67GlnThr: 3.67 ± 2.215
5.505GlnVal: 5.505 ± 1.581
0.0GlnTrp: 0.0 ± 0.0
2.752GlnTyr: 2.752 ± 0.978
0.0GlnXaa: 0.0 ± 0.0
Arg
3.67ArgAla: 3.67 ± 1.848
0.0ArgCys: 0.0 ± 0.0
2.752ArgAsp: 2.752 ± 1.549
3.67ArgGlu: 3.67 ± 1.649
0.917ArgPhe: 0.917 ± 0.842
2.752ArgGly: 2.752 ± 0.978
2.752ArgHis: 2.752 ± 1.069
4.587ArgIle: 4.587 ± 2.003
3.67ArgLys: 3.67 ± 1.809
1.835ArgLeu: 1.835 ± 1.219
0.917ArgMet: 0.917 ± 0.842
1.835ArgAsn: 1.835 ± 1.031
6.422ArgPro: 6.422 ± 1.899
3.67ArgGln: 3.67 ± 3.444
4.587ArgArg: 4.587 ± 2.516
4.587ArgSer: 4.587 ± 1.539
4.587ArgThr: 4.587 ± 2.45
7.339ArgVal: 7.339 ± 1.541
0.0ArgTrp: 0.0 ± 0.0
1.835ArgTyr: 1.835 ± 1.219
0.0ArgXaa: 0.0 ± 0.0
Ser
2.752SerAla: 2.752 ± 1.928
0.0SerCys: 0.0 ± 0.0
3.67SerAsp: 3.67 ± 1.118
3.67SerGlu: 3.67 ± 1.73
3.67SerPhe: 3.67 ± 1.118
4.587SerGly: 4.587 ± 1.167
0.917SerHis: 0.917 ± 1.042
4.587SerIle: 4.587 ± 2.467
2.752SerLys: 2.752 ± 2.525
4.587SerLeu: 4.587 ± 1.752
2.752SerMet: 2.752 ± 3.372
6.422SerAsn: 6.422 ± 1.632
9.174SerPro: 9.174 ± 2.06
2.752SerGln: 2.752 ± 1.334
6.422SerArg: 6.422 ± 3.172
14.679SerSer: 14.679 ± 6.78
3.67SerThr: 3.67 ± 1.835
4.587SerVal: 4.587 ± 2.474
0.0SerTrp: 0.0 ± 0.0
2.752SerTyr: 2.752 ± 1.334
0.0SerXaa: 0.0 ± 0.0
Thr
5.505ThrAla: 5.505 ± 1.01
0.917ThrCys: 0.917 ± 1.137
0.917ThrAsp: 0.917 ± 1.042
0.0ThrGlu: 0.0 ± 0.0
0.917ThrPhe: 0.917 ± 1.042
6.422ThrGly: 6.422 ± 1.82
4.587ThrHis: 4.587 ± 2.117
1.835ThrIle: 1.835 ± 1.011
2.752ThrLys: 2.752 ± 1.549
3.67ThrLeu: 3.67 ± 1.194
0.917ThrMet: 0.917 ± 0.643
3.67ThrAsn: 3.67 ± 1.456
1.835ThrPro: 1.835 ± 2.248
3.67ThrGln: 3.67 ± 2.905
2.752ThrArg: 2.752 ± 1.069
5.505ThrSer: 5.505 ± 3.169
0.917ThrThr: 0.917 ± 1.042
3.67ThrVal: 3.67 ± 1.874
0.0ThrTrp: 0.0 ± 0.0
1.835ThrTyr: 1.835 ± 1.172
0.0ThrXaa: 0.0 ± 0.0
Val
0.917ValAla: 0.917 ± 0.643
0.0ValCys: 0.0 ± 0.0
3.67ValAsp: 3.67 ± 0.986
0.917ValGlu: 0.917 ± 1.137
1.835ValPhe: 1.835 ± 1.162
1.835ValGly: 1.835 ± 1.221
1.835ValHis: 1.835 ± 0.835
5.505ValIle: 5.505 ± 2.846
4.587ValLys: 4.587 ± 2.258
6.422ValLeu: 6.422 ± 3.243
2.752ValMet: 2.752 ± 1.795
2.752ValAsn: 2.752 ± 1.078
3.67ValPro: 3.67 ± 0.986
8.257ValGln: 8.257 ± 2.301
4.587ValArg: 4.587 ± 3.25
1.835ValSer: 1.835 ± 1.581
5.505ValThr: 5.505 ± 2.505
3.67ValVal: 3.67 ± 1.526
0.0ValTrp: 0.0 ± 0.0
6.422ValTyr: 6.422 ± 2.292
0.0ValXaa: 0.0 ± 0.0
Trp
3.67TrpAla: 3.67 ± 1.775
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.917TrpGly: 0.917 ± 0.643
0.917TrpHis: 0.917 ± 0.842
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.917TrpMet: 0.917 ± 0.842
0.917TrpAsn: 0.917 ± 1.042
0.0TrpPro: 0.0 ± 0.0
1.835TrpGln: 1.835 ± 1.148
0.917TrpArg: 0.917 ± 1.083
0.917TrpSer: 0.917 ± 1.083
0.917TrpThr: 0.917 ± 1.042
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.917TrpTyr: 0.917 ± 0.643
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.835TyrAla: 1.835 ± 1.683
0.0TyrCys: 0.0 ± 0.0
2.752TyrAsp: 2.752 ± 2.202
0.917TyrGlu: 0.917 ± 0.842
1.835TyrPhe: 1.835 ± 1.162
0.917TyrGly: 0.917 ± 0.643
0.917TyrHis: 0.917 ± 0.643
3.67TyrIle: 3.67 ± 1.823
0.917TyrLys: 0.917 ± 0.643
3.67TyrLeu: 3.67 ± 1.552
0.917TyrMet: 0.917 ± 1.122
1.835TyrAsn: 1.835 ± 0.835
0.917TyrPro: 0.917 ± 0.643
1.835TyrGln: 1.835 ± 1.221
2.752TyrArg: 2.752 ± 2.525
3.67TyrSer: 3.67 ± 1.275
0.917TyrThr: 0.917 ± 1.083
3.67TyrVal: 3.67 ± 1.848
0.0TyrTrp: 0.0 ± 0.0
0.917TyrTyr: 0.917 ± 1.083
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1091 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski