Amino acid dipepetide frequency for Rattus norvegicus polyomavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.489AlaAla: 7.489 ± 3.983
0.0AlaCys: 0.0 ± 0.0
2.496AlaAsp: 2.496 ± 0.427
2.996AlaGlu: 2.996 ± 0.985
0.999AlaPhe: 0.999 ± 0.546
5.492AlaGly: 5.492 ± 2.238
0.999AlaHis: 0.999 ± 0.466
7.988AlaIle: 7.988 ± 2.774
1.498AlaLys: 1.498 ± 0.712
4.993AlaLeu: 4.993 ± 1.841
0.0AlaMet: 0.0 ± 0.0
2.496AlaAsn: 2.496 ± 1.094
1.997AlaPro: 1.997 ± 2.118
1.997AlaGln: 1.997 ± 0.884
5.492AlaArg: 5.492 ± 2.129
6.49AlaSer: 6.49 ± 1.826
2.496AlaThr: 2.496 ± 0.812
3.495AlaVal: 3.495 ± 1.166
2.996AlaTrp: 2.996 ± 1.424
0.999AlaTyr: 0.999 ± 0.706
0.0AlaXaa: 0.0 ± 0.0
Cys
0.999CysAla: 0.999 ± 0.466
0.499CysCys: 0.499 ± 0.583
1.498CysAsp: 1.498 ± 0.712
0.999CysGlu: 0.999 ± 0.466
1.997CysPhe: 1.997 ± 1.113
0.499CysGly: 0.499 ± 0.661
0.499CysHis: 0.499 ± 0.583
0.999CysIle: 0.999 ± 0.546
3.495CysLys: 3.495 ± 1.678
0.499CysLeu: 0.499 ± 0.353
0.499CysMet: 0.499 ± 0.353
1.498CysAsn: 1.498 ± 0.623
0.0CysPro: 0.0 ± 0.0
1.498CysGln: 1.498 ± 0.635
1.498CysArg: 1.498 ± 0.801
1.498CysSer: 1.498 ± 0.623
2.496CysThr: 2.496 ± 0.944
0.999CysVal: 0.999 ± 0.546
0.499CysTrp: 0.499 ± 0.661
2.496CysTyr: 2.496 ± 1.5
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.499AspCys: 0.499 ± 0.353
1.498AspAsp: 1.498 ± 0.542
3.495AspGlu: 3.495 ± 1.245
2.496AspPhe: 2.496 ± 1.764
2.996AspGly: 2.996 ± 0.954
0.499AspHis: 0.499 ± 0.353
3.495AspIle: 3.495 ± 0.95
1.997AspLys: 1.997 ± 0.982
4.993AspLeu: 4.993 ± 1.672
1.498AspMet: 1.498 ± 0.542
2.496AspAsn: 2.496 ± 0.944
3.994AspPro: 3.994 ± 1.708
0.999AspGln: 0.999 ± 0.466
1.997AspArg: 1.997 ± 0.982
2.496AspSer: 2.496 ± 0.824
1.997AspThr: 1.997 ± 0.684
3.495AspVal: 3.495 ± 0.835
0.999AspTrp: 0.999 ± 0.607
0.999AspTyr: 0.999 ± 0.466
0.0AspXaa: 0.0 ± 0.0
Glu
6.99GluAla: 6.99 ± 1.425
1.997GluCys: 1.997 ± 0.639
3.495GluAsp: 3.495 ± 2.47
9.486GluGlu: 9.486 ± 2.383
1.498GluPhe: 1.498 ± 0.712
3.994GluGly: 3.994 ± 2.06
1.498GluHis: 1.498 ± 0.542
0.999GluIle: 0.999 ± 0.85
5.492GluLys: 5.492 ± 1.904
7.489GluLeu: 7.489 ± 1.047
1.997GluMet: 1.997 ± 0.442
1.997GluAsn: 1.997 ± 1.701
4.493GluPro: 4.493 ± 1.335
3.495GluGln: 3.495 ± 1.576
3.994GluArg: 3.994 ± 1.085
0.999GluSer: 0.999 ± 0.466
2.496GluThr: 2.496 ± 1.23
2.496GluVal: 2.496 ± 1.635
0.499GluTrp: 0.499 ± 0.353
2.996GluTyr: 2.996 ± 1.377
0.0GluXaa: 0.0 ± 0.0
Phe
1.498PheAla: 1.498 ± 0.542
1.997PheCys: 1.997 ± 0.982
0.499PheAsp: 0.499 ± 0.353
3.495PheGlu: 3.495 ± 1.678
1.997PhePhe: 1.997 ± 0.639
3.994PheGly: 3.994 ± 1.006
0.499PheHis: 0.499 ± 0.353
0.499PheIle: 0.499 ± 0.353
1.997PheLys: 1.997 ± 1.411
3.994PheLeu: 3.994 ± 1.47
0.999PheMet: 0.999 ± 0.706
1.498PheAsn: 1.498 ± 0.542
0.999PhePro: 0.999 ± 0.706
1.498PheGln: 1.498 ± 0.811
2.496PheArg: 2.496 ± 1.174
1.498PheSer: 1.498 ± 0.712
1.498PheThr: 1.498 ± 0.722
1.498PheVal: 1.498 ± 0.712
1.498PheTrp: 1.498 ± 0.623
0.999PheTyr: 0.999 ± 0.607
0.0PheXaa: 0.0 ± 0.0
Gly
2.496GlyAla: 2.496 ± 1.623
0.999GlyCys: 0.999 ± 0.706
4.993GlyAsp: 4.993 ± 1.183
3.994GlyGlu: 3.994 ± 0.901
2.496GlyPhe: 2.496 ± 1.171
9.486GlyGly: 9.486 ± 2.479
0.999GlyHis: 0.999 ± 0.546
3.994GlyIle: 3.994 ± 1.106
2.996GlyLys: 2.996 ± 1.485
2.996GlyLeu: 2.996 ± 0.692
0.499GlyMet: 0.499 ± 0.474
3.495GlyAsn: 3.495 ± 0.628
4.993GlyPro: 4.993 ± 1.609
4.993GlyGln: 4.993 ± 1.757
2.996GlyArg: 2.996 ± 1.58
6.49GlySer: 6.49 ± 1.779
3.994GlyThr: 3.994 ± 0.963
6.49GlyVal: 6.49 ± 2.056
0.0GlyTrp: 0.0 ± 0.0
0.999GlyTyr: 0.999 ± 0.647
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.999HisCys: 0.999 ± 0.546
0.499HisAsp: 0.499 ± 0.353
1.498HisGlu: 1.498 ± 0.712
0.999HisPhe: 0.999 ± 0.466
1.498HisGly: 1.498 ± 0.677
0.499HisHis: 0.499 ± 0.353
0.999HisIle: 0.999 ± 0.546
0.999HisLys: 0.999 ± 0.546
1.997HisLeu: 1.997 ± 0.911
1.498HisMet: 1.498 ± 0.712
0.999HisAsn: 0.999 ± 0.786
0.999HisPro: 0.999 ± 0.546
0.0HisGln: 0.0 ± 0.0
3.495HisArg: 3.495 ± 1.182
1.498HisSer: 1.498 ± 0.933
2.996HisThr: 2.996 ± 1.083
0.999HisVal: 0.999 ± 0.786
0.0HisTrp: 0.0 ± 0.0
2.496HisTyr: 2.496 ± 0.427
0.0HisXaa: 0.0 ± 0.0
Ile
4.493IleAla: 4.493 ± 1.954
1.498IleCys: 1.498 ± 1.263
0.999IleAsp: 0.999 ± 0.706
2.496IleGlu: 2.496 ± 1.02
2.496IlePhe: 2.496 ± 0.728
2.496IleGly: 2.496 ± 1.476
1.997IleHis: 1.997 ± 0.633
0.999IleIle: 0.999 ± 0.466
0.999IleLys: 0.999 ± 0.85
5.991IleLeu: 5.991 ± 1.658
0.0IleMet: 0.0 ± 0.0
1.498IleAsn: 1.498 ± 1.059
5.492IlePro: 5.492 ± 1.233
3.495IleGln: 3.495 ± 0.746
2.496IleArg: 2.496 ± 0.427
0.999IleSer: 0.999 ± 0.85
2.496IleThr: 2.496 ± 1.376
4.993IleVal: 4.993 ± 0.662
0.499IleTrp: 0.499 ± 0.353
0.499IleTyr: 0.499 ± 0.353
0.0IleXaa: 0.0 ± 0.0
Lys
3.994LysAla: 3.994 ± 1.106
1.997LysCys: 1.997 ± 1.093
1.498LysAsp: 1.498 ± 0.712
4.493LysGlu: 4.493 ± 1.493
0.999LysPhe: 0.999 ± 0.546
5.492LysGly: 5.492 ± 2.095
1.498LysHis: 1.498 ± 1.059
2.496LysIle: 2.496 ± 0.427
7.988LysLys: 7.988 ± 1.187
5.492LysLeu: 5.492 ± 1.836
2.496LysMet: 2.496 ± 0.897
3.495LysAsn: 3.495 ± 1.401
1.997LysPro: 1.997 ± 0.546
1.997LysGln: 1.997 ± 0.754
6.49LysArg: 6.49 ± 1.115
2.996LysSer: 2.996 ± 1.141
3.994LysThr: 3.994 ± 1.417
4.993LysVal: 4.993 ± 2.158
0.0LysTrp: 0.0 ± 0.0
1.997LysTyr: 1.997 ± 0.982
0.0LysXaa: 0.0 ± 0.0
Leu
3.495LeuAla: 3.495 ± 1.293
1.997LeuCys: 1.997 ± 0.915
4.993LeuAsp: 4.993 ± 0.888
8.987LeuGlu: 8.987 ± 1.961
1.997LeuPhe: 1.997 ± 0.982
4.993LeuGly: 4.993 ± 0.801
3.495LeuHis: 3.495 ± 1.213
3.994LeuIle: 3.994 ± 0.726
4.993LeuLys: 4.993 ± 1.347
11.483LeuLeu: 11.483 ± 1.498
2.996LeuMet: 2.996 ± 1.679
6.49LeuAsn: 6.49 ± 1.951
6.49LeuPro: 6.49 ± 2.114
4.493LeuGln: 4.493 ± 1.851
3.994LeuArg: 3.994 ± 1.667
4.493LeuSer: 4.493 ± 1.073
3.994LeuThr: 3.994 ± 1.419
2.496LeuVal: 2.496 ± 0.944
0.0LeuTrp: 0.0 ± 0.0
5.991LeuTyr: 5.991 ± 1.085
0.0LeuXaa: 0.0 ± 0.0
Met
1.997MetAla: 1.997 ± 0.442
0.499MetCys: 0.499 ± 0.353
1.498MetAsp: 1.498 ± 0.712
1.997MetGlu: 1.997 ± 0.925
0.999MetPhe: 0.999 ± 0.466
1.997MetGly: 1.997 ± 0.546
0.999MetHis: 0.999 ± 0.607
1.498MetIle: 1.498 ± 0.722
0.999MetLys: 0.999 ± 0.546
1.498MetLeu: 1.498 ± 0.933
0.0MetMet: 0.0 ± 0.0
1.498MetAsn: 1.498 ± 0.635
1.997MetPro: 1.997 ± 0.633
1.498MetGln: 1.498 ± 0.542
0.499MetArg: 0.499 ± 0.661
2.996MetSer: 2.996 ± 1.589
0.499MetThr: 0.499 ± 0.353
0.999MetVal: 0.999 ± 0.466
0.499MetTrp: 0.499 ± 0.353
0.999MetTyr: 0.999 ± 1.059
0.0MetXaa: 0.0 ± 0.0
Asn
1.498AsnAla: 1.498 ± 0.542
0.499AsnCys: 0.499 ± 0.583
1.997AsnAsp: 1.997 ± 0.915
0.999AsnGlu: 0.999 ± 0.466
1.498AsnPhe: 1.498 ± 0.635
2.496AsnGly: 2.496 ± 1.113
0.499AsnHis: 0.499 ± 0.529
1.997AsnIle: 1.997 ± 0.754
4.493AsnLys: 4.493 ± 1.434
6.49AsnLeu: 6.49 ± 2.244
2.496AsnMet: 2.496 ± 0.817
3.495AsnAsn: 3.495 ± 0.96
2.496AsnPro: 2.496 ± 0.836
1.997AsnGln: 1.997 ± 0.442
2.996AsnArg: 2.996 ± 1.094
3.495AsnSer: 3.495 ± 0.595
2.996AsnThr: 2.996 ± 0.912
3.994AsnVal: 3.994 ± 0.857
0.499AsnTrp: 0.499 ± 0.353
0.499AsnTyr: 0.499 ± 0.353
0.0AsnXaa: 0.0 ± 0.0
Pro
0.999ProAla: 0.999 ± 0.466
1.498ProCys: 1.498 ± 1.278
4.993ProAsp: 4.993 ± 1.325
2.996ProGlu: 2.996 ± 1.082
1.498ProPhe: 1.498 ± 0.635
4.993ProGly: 4.993 ± 1.006
1.498ProHis: 1.498 ± 0.635
1.997ProIle: 1.997 ± 0.703
6.99ProLys: 6.99 ± 1.96
2.496ProLeu: 2.496 ± 1.23
0.999ProMet: 0.999 ± 0.786
2.496ProAsn: 2.496 ± 0.427
4.993ProPro: 4.993 ± 1.032
2.996ProGln: 2.996 ± 1.354
1.498ProArg: 1.498 ± 1.106
3.994ProSer: 3.994 ± 1.278
2.496ProThr: 2.496 ± 1.355
5.991ProVal: 5.991 ± 1.629
0.0ProTrp: 0.0 ± 0.0
0.999ProTyr: 0.999 ± 0.466
0.0ProXaa: 0.0 ± 0.0
Gln
5.492GlnAla: 5.492 ± 1.178
0.499GlnCys: 0.499 ± 0.529
1.498GlnAsp: 1.498 ± 0.542
2.496GlnGlu: 2.496 ± 0.944
2.996GlnPhe: 2.996 ± 1.25
5.492GlnGly: 5.492 ± 1.178
0.499GlnHis: 0.499 ± 0.353
3.495GlnIle: 3.495 ± 0.95
1.997GlnLys: 1.997 ± 0.915
3.994GlnLeu: 3.994 ± 1.14
0.499GlnMet: 0.499 ± 0.529
1.997GlnAsn: 1.997 ± 1.029
1.498GlnPro: 1.498 ± 0.544
3.495GlnGln: 3.495 ± 1.131
3.994GlnArg: 3.994 ± 2.106
1.498GlnSer: 1.498 ± 0.542
1.997GlnThr: 1.997 ± 1.258
2.996GlnVal: 2.996 ± 1.297
1.997GlnTrp: 1.997 ± 1.213
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.99ArgAla: 6.99 ± 1.949
1.997ArgCys: 1.997 ± 0.854
1.997ArgAsp: 1.997 ± 1.411
4.493ArgGlu: 4.493 ± 1.01
2.496ArgPhe: 2.496 ± 0.824
1.498ArgGly: 1.498 ± 0.841
0.999ArgHis: 0.999 ± 0.607
2.496ArgIle: 2.496 ± 1.209
5.492ArgLys: 5.492 ± 0.995
7.489ArgLeu: 7.489 ± 1.708
0.999ArgMet: 0.999 ± 0.786
2.996ArgAsn: 2.996 ± 1.218
1.498ArgPro: 1.498 ± 0.466
0.999ArgGln: 0.999 ± 0.466
3.495ArgArg: 3.495 ± 0.589
2.996ArgSer: 2.996 ± 1.875
3.495ArgThr: 3.495 ± 1.024
5.492ArgVal: 5.492 ± 0.966
0.499ArgTrp: 0.499 ± 0.583
1.498ArgTyr: 1.498 ± 0.623
0.0ArgXaa: 0.0 ± 0.0
Ser
8.487SerAla: 8.487 ± 3.014
1.498SerCys: 1.498 ± 1.278
2.496SerAsp: 2.496 ± 1.171
5.991SerGlu: 5.991 ± 1.462
0.499SerPhe: 0.499 ± 0.353
2.996SerGly: 2.996 ± 1.082
0.499SerHis: 0.499 ± 0.661
0.499SerIle: 0.499 ± 0.353
2.496SerLys: 2.496 ± 1.897
4.493SerLeu: 4.493 ± 0.95
0.999SerMet: 0.999 ± 1.059
4.993SerAsn: 4.993 ± 0.608
1.498SerPro: 1.498 ± 0.722
3.994SerGln: 3.994 ± 2.823
3.994SerArg: 3.994 ± 1.14
3.495SerSer: 3.495 ± 1.807
6.49SerThr: 6.49 ± 2.598
1.997SerVal: 1.997 ± 0.442
0.499SerTrp: 0.499 ± 0.583
1.997SerTyr: 1.997 ± 0.806
0.0SerXaa: 0.0 ± 0.0
Thr
1.997ThrAla: 1.997 ± 0.884
3.994ThrCys: 3.994 ± 0.896
0.999ThrAsp: 0.999 ± 0.466
1.997ThrGlu: 1.997 ± 1.086
1.498ThrPhe: 1.498 ± 1.263
3.994ThrGly: 3.994 ± 1.14
0.499ThrHis: 0.499 ± 0.529
3.994ThrIle: 3.994 ± 0.885
4.493ThrLys: 4.493 ± 1.216
5.991ThrLeu: 5.991 ± 1.376
2.496ThrMet: 2.496 ± 0.731
0.0ThrAsn: 0.0 ± 0.0
3.994ThrPro: 3.994 ± 1.142
2.996ThrGln: 2.996 ± 1.01
4.493ThrArg: 4.493 ± 0.665
2.996ThrSer: 2.996 ± 1.041
2.996ThrThr: 2.996 ± 0.608
3.495ThrVal: 3.495 ± 0.593
0.0ThrTrp: 0.0 ± 0.0
2.496ThrTyr: 2.496 ± 0.427
0.0ThrXaa: 0.0 ± 0.0
Val
3.495ValAla: 3.495 ± 0.835
0.499ValCys: 0.499 ± 0.529
2.496ValAsp: 2.496 ± 1.094
3.495ValGlu: 3.495 ± 0.746
2.496ValPhe: 2.496 ± 1.292
3.994ValGly: 3.994 ± 2.302
3.495ValHis: 3.495 ± 1.527
0.999ValIle: 0.999 ± 0.466
2.496ValLys: 2.496 ± 1.233
6.49ValLeu: 6.49 ± 1.606
1.498ValMet: 1.498 ± 1.253
1.997ValAsn: 1.997 ± 1.022
6.49ValPro: 6.49 ± 1.053
5.991ValGln: 5.991 ± 2.666
1.498ValArg: 1.498 ± 0.841
5.991ValSer: 5.991 ± 1.695
3.994ValThr: 3.994 ± 2.371
5.492ValVal: 5.492 ± 1.244
0.999ValTrp: 0.999 ± 0.786
1.498ValTyr: 1.498 ± 0.635
0.0ValXaa: 0.0 ± 0.0
Trp
0.499TrpAla: 0.499 ± 0.529
0.0TrpCys: 0.0 ± 0.0
1.498TrpAsp: 1.498 ± 0.712
1.997TrpGlu: 1.997 ± 0.639
0.499TrpPhe: 0.499 ± 0.583
0.999TrpGly: 0.999 ± 0.546
0.499TrpHis: 0.499 ± 0.353
2.996TrpIle: 2.996 ± 1.82
1.498TrpLys: 1.498 ± 0.712
0.999TrpLeu: 0.999 ± 0.546
0.0TrpMet: 0.0 ± 0.0
0.999TrpAsn: 0.999 ± 0.85
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.499TrpThr: 0.499 ± 0.529
0.0TrpVal: 0.0 ± 0.0
0.499TrpTrp: 0.499 ± 0.353
0.499TrpTyr: 0.499 ± 0.353
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.499TyrAla: 0.499 ± 0.353
1.498TyrCys: 1.498 ± 0.712
0.999TyrAsp: 0.999 ± 0.466
0.0TyrGlu: 0.0 ± 0.0
2.496TyrPhe: 2.496 ± 0.812
0.999TyrGly: 0.999 ± 0.706
2.996TyrHis: 2.996 ± 0.35
0.499TyrIle: 0.499 ± 0.353
2.996TyrLys: 2.996 ± 0.976
1.997TyrLeu: 1.997 ± 0.65
2.496TyrMet: 2.496 ± 1.056
0.999TyrAsn: 0.999 ± 0.46
0.499TyrPro: 0.499 ± 0.529
0.0TyrGln: 0.0 ± 0.0
2.496TyrArg: 2.496 ± 0.549
2.996TyrSer: 2.996 ± 0.873
1.997TyrThr: 1.997 ± 0.932
2.996TyrVal: 2.996 ± 0.35
1.498TyrTrp: 1.498 ± 0.933
1.498TyrTyr: 1.498 ± 0.542
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2004 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski