Amino acid dipepetide frequency for Garlic virus C

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.792AlaAla: 6.792 ± 1.376
1.509AlaCys: 1.509 ± 0.492
1.509AlaAsp: 1.509 ± 0.492
4.528AlaGlu: 4.528 ± 1.322
3.396AlaPhe: 3.396 ± 1.409
3.396AlaGly: 3.396 ± 1.594
1.887AlaHis: 1.887 ± 0.717
2.264AlaIle: 2.264 ± 1.259
5.283AlaLys: 5.283 ± 1.267
9.811AlaLeu: 9.811 ± 3.161
2.264AlaMet: 2.264 ± 0.813
4.906AlaAsn: 4.906 ± 1.316
2.264AlaPro: 2.264 ± 1.3
1.887AlaGln: 1.887 ± 0.83
4.906AlaArg: 4.906 ± 0.604
2.264AlaSer: 2.264 ± 0.84
5.66AlaThr: 5.66 ± 2.016
6.038AlaVal: 6.038 ± 0.731
0.755AlaTrp: 0.755 ± 0.752
3.019AlaTyr: 3.019 ± 1.286
0.0AlaXaa: 0.0 ± 0.0
Cys
0.755CysAla: 0.755 ± 0.564
0.377CysCys: 0.377 ± 0.639
1.132CysAsp: 1.132 ± 0.63
1.132CysGlu: 1.132 ± 0.419
1.132CysPhe: 1.132 ± 1.186
2.264CysGly: 2.264 ± 1.3
0.377CysHis: 0.377 ± 0.216
0.377CysIle: 0.377 ± 0.652
0.755CysLys: 0.755 ± 0.564
1.509CysLeu: 1.509 ± 0.647
0.377CysMet: 0.377 ± 0.411
0.755CysAsn: 0.755 ± 0.459
0.377CysPro: 0.377 ± 0.216
0.755CysGln: 0.755 ± 0.387
1.509CysArg: 1.509 ± 0.613
1.887CysSer: 1.887 ± 0.679
0.377CysThr: 0.377 ± 0.558
0.377CysVal: 0.377 ± 0.466
0.0CysTrp: 0.0 ± 0.0
1.509CysTyr: 1.509 ± 0.884
0.0CysXaa: 0.0 ± 0.0
Asp
4.151AspAla: 4.151 ± 1.359
1.509AspCys: 1.509 ± 0.602
3.019AspAsp: 3.019 ± 1.204
6.038AspGlu: 6.038 ± 1.212
3.019AspPhe: 3.019 ± 0.78
1.132AspGly: 1.132 ± 0.63
0.755AspHis: 0.755 ± 0.431
2.264AspIle: 2.264 ± 0.533
3.774AspLys: 3.774 ± 1.697
7.925AspLeu: 7.925 ± 1.365
0.0AspMet: 0.0 ± 0.0
2.264AspAsn: 2.264 ± 1.421
3.774AspPro: 3.774 ± 1.167
2.642AspGln: 2.642 ± 0.946
2.264AspArg: 2.264 ± 0.838
4.528AspSer: 4.528 ± 0.962
3.396AspThr: 3.396 ± 0.837
2.642AspVal: 2.642 ± 0.885
0.755AspTrp: 0.755 ± 0.431
3.019AspTyr: 3.019 ± 1.005
0.0AspXaa: 0.0 ± 0.0
Glu
4.151GluAla: 4.151 ± 1.359
0.755GluCys: 0.755 ± 0.431
1.887GluAsp: 1.887 ± 1.078
5.66GluGlu: 5.66 ± 1.829
2.264GluPhe: 2.264 ± 0.552
3.396GluGly: 3.396 ± 1.214
1.132GluHis: 1.132 ± 0.419
3.774GluIle: 3.774 ± 0.759
1.887GluLys: 1.887 ± 1.078
6.792GluLeu: 6.792 ± 2.148
0.755GluMet: 0.755 ± 0.459
2.264GluAsn: 2.264 ± 0.533
3.019GluPro: 3.019 ± 1.012
2.642GluGln: 2.642 ± 0.768
3.019GluArg: 3.019 ± 1.085
4.906GluSer: 4.906 ± 0.974
3.396GluThr: 3.396 ± 1.274
3.019GluVal: 3.019 ± 1.286
0.377GluTrp: 0.377 ± 0.466
0.755GluTyr: 0.755 ± 0.459
0.0GluXaa: 0.0 ± 0.0
Phe
3.019PheAla: 3.019 ± 0.874
1.132PheCys: 1.132 ± 0.983
3.019PheAsp: 3.019 ± 0.877
3.019PheGlu: 3.019 ± 1.132
1.509PhePhe: 1.509 ± 1.041
2.264PheGly: 2.264 ± 0.838
0.755PheHis: 0.755 ± 0.431
3.019PheIle: 3.019 ± 0.99
1.887PheLys: 1.887 ± 0.636
1.132PheLeu: 1.132 ± 0.647
1.509PheMet: 1.509 ± 0.545
1.887PheAsn: 1.887 ± 0.64
2.264PhePro: 2.264 ± 0.725
3.019PheGln: 3.019 ± 1.058
0.755PheArg: 0.755 ± 0.564
3.774PheSer: 3.774 ± 1.165
2.264PheThr: 2.264 ± 0.585
1.509PheVal: 1.509 ± 0.918
0.0PheTrp: 0.0 ± 0.0
1.509PheTyr: 1.509 ± 0.492
0.0PheXaa: 0.0 ± 0.0
Gly
4.528GlyAla: 4.528 ± 0.966
1.132GlyCys: 1.132 ± 0.468
3.019GlyAsp: 3.019 ± 1.056
3.396GlyGlu: 3.396 ± 1.274
1.132GlyPhe: 1.132 ± 0.983
3.774GlyGly: 3.774 ± 1.026
1.509GlyHis: 1.509 ± 0.492
2.264GlyIle: 2.264 ± 0.585
4.151GlyLys: 4.151 ± 1.443
3.019GlyLeu: 3.019 ± 0.824
1.509GlyMet: 1.509 ± 0.884
1.509GlyAsn: 1.509 ± 0.821
3.396GlyPro: 3.396 ± 1.724
1.132GlyGln: 1.132 ± 0.419
3.019GlyArg: 3.019 ± 1.393
3.774GlySer: 3.774 ± 1.909
3.396GlyThr: 3.396 ± 1.492
1.509GlyVal: 1.509 ± 0.918
0.755GlyTrp: 0.755 ± 0.431
1.132GlyTyr: 1.132 ± 0.567
0.0GlyXaa: 0.0 ± 0.0
His
3.019HisAla: 3.019 ± 0.764
0.377HisCys: 0.377 ± 0.216
2.264HisAsp: 2.264 ± 1.161
1.132HisGlu: 1.132 ± 0.797
3.019HisPhe: 3.019 ± 0.68
2.642HisGly: 2.642 ± 0.859
1.132HisHis: 1.132 ± 0.676
2.264HisIle: 2.264 ± 0.533
0.755HisLys: 0.755 ± 0.387
3.774HisLeu: 3.774 ± 1.413
0.755HisMet: 0.755 ± 0.713
1.509HisAsn: 1.509 ± 0.91
1.509HisPro: 1.509 ± 1.03
2.264HisGln: 2.264 ± 0.838
1.132HisArg: 1.132 ± 0.982
2.264HisSer: 2.264 ± 1.558
2.642HisThr: 2.642 ± 0.824
2.642HisVal: 2.642 ± 1.246
0.0HisTrp: 0.0 ± 0.0
1.132HisTyr: 1.132 ± 0.63
0.0HisXaa: 0.0 ± 0.0
Ile
3.396IleAla: 3.396 ± 0.978
1.132IleCys: 1.132 ± 0.982
1.509IleAsp: 1.509 ± 0.862
3.019IleGlu: 3.019 ± 0.351
1.887IlePhe: 1.887 ± 0.712
3.396IleGly: 3.396 ± 1.395
3.396IleHis: 3.396 ± 1.524
1.887IleIle: 1.887 ± 0.636
2.642IleLys: 2.642 ± 1.087
4.151IleLeu: 4.151 ± 1.848
1.509IleMet: 1.509 ± 0.862
2.642IleAsn: 2.642 ± 0.698
1.132IlePro: 1.132 ± 0.647
1.132IleGln: 1.132 ± 0.419
3.396IleArg: 3.396 ± 0.767
3.396IleSer: 3.396 ± 0.816
3.774IleThr: 3.774 ± 0.833
3.396IleVal: 3.396 ± 1.035
0.0IleTrp: 0.0 ± 0.0
1.887IleTyr: 1.887 ± 1.177
0.0IleXaa: 0.0 ± 0.0
Lys
4.528LysAla: 4.528 ± 1.564
0.377LysCys: 0.377 ± 0.639
3.774LysAsp: 3.774 ± 1.044
1.132LysGlu: 1.132 ± 0.419
0.755LysPhe: 0.755 ± 0.442
1.132LysGly: 1.132 ± 0.58
2.264LysHis: 2.264 ± 0.895
2.264LysIle: 2.264 ± 1.293
1.132LysLys: 1.132 ± 0.647
6.415LysLeu: 6.415 ± 1.378
1.509LysMet: 1.509 ± 0.698
1.132LysAsn: 1.132 ± 0.415
4.528LysPro: 4.528 ± 1.723
1.132LysGln: 1.132 ± 0.688
6.415LysArg: 6.415 ± 1.941
2.642LysSer: 2.642 ± 1.087
4.528LysThr: 4.528 ± 0.829
1.887LysVal: 1.887 ± 0.86
0.755LysTrp: 0.755 ± 0.431
0.755LysTyr: 0.755 ± 0.431
0.0LysXaa: 0.0 ± 0.0
Leu
6.792LeuAla: 6.792 ± 1.102
1.509LeuCys: 1.509 ± 0.602
5.283LeuAsp: 5.283 ± 1.171
5.66LeuGlu: 5.66 ± 1.315
6.038LeuPhe: 6.038 ± 1.501
4.151LeuGly: 4.151 ± 1.353
4.906LeuHis: 4.906 ± 3.229
4.906LeuIle: 4.906 ± 1.064
4.151LeuLys: 4.151 ± 1.055
10.566LeuLeu: 10.566 ± 2.941
1.887LeuMet: 1.887 ± 0.64
6.038LeuAsn: 6.038 ± 2.256
9.434LeuPro: 9.434 ± 0.734
5.283LeuGln: 5.283 ± 2.226
6.038LeuArg: 6.038 ± 0.923
6.038LeuSer: 6.038 ± 1.247
9.057LeuThr: 9.057 ± 1.555
5.66LeuVal: 5.66 ± 1.817
1.132LeuTrp: 1.132 ± 0.647
3.396LeuTyr: 3.396 ± 1.144
0.0LeuXaa: 0.0 ± 0.0
Met
0.755MetAla: 0.755 ± 0.431
0.377MetCys: 0.377 ± 0.216
1.509MetAsp: 1.509 ± 0.543
0.755MetGlu: 0.755 ± 0.431
0.0MetPhe: 0.0 ± 0.0
0.377MetGly: 0.377 ± 0.216
0.377MetHis: 0.377 ± 0.639
0.377MetIle: 0.377 ± 0.543
0.755MetLys: 0.755 ± 0.922
0.755MetLeu: 0.755 ± 0.942
0.0MetMet: 0.0 ± 0.0
0.755MetAsn: 0.755 ± 0.387
0.755MetPro: 0.755 ± 0.387
1.132MetGln: 1.132 ± 0.647
0.755MetArg: 0.755 ± 0.442
2.264MetSer: 2.264 ± 1.71
3.396MetThr: 3.396 ± 0.768
0.755MetVal: 0.755 ± 0.442
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.66AsnAla: 5.66 ± 1.316
0.755AsnCys: 0.755 ± 0.387
2.264AsnAsp: 2.264 ± 0.612
1.887AsnGlu: 1.887 ± 0.607
1.509AsnPhe: 1.509 ± 1.04
2.264AsnGly: 2.264 ± 1.562
2.264AsnHis: 2.264 ± 1.346
1.887AsnIle: 1.887 ± 1.207
3.396AsnLys: 3.396 ± 1.557
6.792AsnLeu: 6.792 ± 2.371
0.377AsnMet: 0.377 ± 0.91
1.887AsnAsn: 1.887 ± 1.169
1.887AsnPro: 1.887 ± 0.83
1.509AsnGln: 1.509 ± 0.447
2.642AsnArg: 2.642 ± 0.876
1.887AsnSer: 1.887 ± 0.395
1.887AsnThr: 1.887 ± 0.623
3.019AsnVal: 3.019 ± 1.026
0.755AsnTrp: 0.755 ± 0.752
1.509AsnTyr: 1.509 ± 0.566
0.0AsnXaa: 0.0 ± 0.0
Pro
3.019ProAla: 3.019 ± 0.584
0.377ProCys: 0.377 ± 0.558
3.774ProAsp: 3.774 ± 1.796
3.396ProGlu: 3.396 ± 1.94
1.887ProPhe: 1.887 ± 0.918
2.264ProGly: 2.264 ± 1.559
4.151ProHis: 4.151 ± 1.309
2.642ProIle: 2.642 ± 1.889
2.264ProLys: 2.264 ± 0.83
4.151ProLeu: 4.151 ± 0.728
0.755ProMet: 0.755 ± 0.931
1.887ProAsn: 1.887 ± 0.64
6.038ProPro: 6.038 ± 1.907
1.887ProGln: 1.887 ± 1.394
1.887ProArg: 1.887 ± 0.522
5.66ProSer: 5.66 ± 1.921
8.679ProThr: 8.679 ± 0.816
2.642ProVal: 2.642 ± 1.509
0.377ProTrp: 0.377 ± 0.216
2.264ProTyr: 2.264 ± 0.633
0.0ProXaa: 0.0 ± 0.0
Gln
4.151GlnAla: 4.151 ± 0.978
0.0GlnCys: 0.0 ± 0.0
2.264GlnAsp: 2.264 ± 0.552
1.509GlnGlu: 1.509 ± 0.774
1.509GlnPhe: 1.509 ± 0.69
3.396GlnGly: 3.396 ± 1.929
1.132GlnHis: 1.132 ± 0.419
3.396GlnIle: 3.396 ± 0.5
0.755GlnLys: 0.755 ± 0.387
7.17GlnLeu: 7.17 ± 1.586
0.0GlnMet: 0.0 ± 0.0
3.019GlnAsn: 3.019 ± 0.757
3.774GlnPro: 3.774 ± 1.358
4.151GlnGln: 4.151 ± 1.133
2.642GlnArg: 2.642 ± 1.099
4.151GlnSer: 4.151 ± 1.055
4.906GlnThr: 4.906 ± 1.405
1.132GlnVal: 1.132 ± 0.829
0.755GlnTrp: 0.755 ± 0.431
0.377GlnTyr: 0.377 ± 0.216
0.0GlnXaa: 0.0 ± 0.0
Arg
4.906ArgAla: 4.906 ± 1.242
1.132ArgCys: 1.132 ± 1.084
4.151ArgAsp: 4.151 ± 1.487
4.528ArgGlu: 4.528 ± 1.048
1.887ArgPhe: 1.887 ± 0.636
0.755ArgGly: 0.755 ± 0.387
1.509ArgHis: 1.509 ± 0.464
3.774ArgIle: 3.774 ± 0.867
3.396ArgLys: 3.396 ± 1.326
6.792ArgLeu: 6.792 ± 1.361
0.377ArgMet: 0.377 ± 0.466
1.887ArgAsn: 1.887 ± 1.207
3.396ArgPro: 3.396 ± 0.857
4.528ArgGln: 4.528 ± 1.104
4.528ArgArg: 4.528 ± 2.358
3.019ArgSer: 3.019 ± 1.007
1.509ArgThr: 1.509 ± 0.464
1.132ArgVal: 1.132 ± 0.989
0.0ArgTrp: 0.0 ± 0.0
2.264ArgTyr: 2.264 ± 1.036
0.0ArgXaa: 0.0 ± 0.0
Ser
2.642SerAla: 2.642 ± 1.322
1.509SerCys: 1.509 ± 0.786
8.302SerAsp: 8.302 ± 2.028
3.019SerGlu: 3.019 ± 1.107
1.887SerPhe: 1.887 ± 1.287
4.528SerGly: 4.528 ± 0.718
1.887SerHis: 1.887 ± 0.607
2.642SerIle: 2.642 ± 0.663
3.774SerLys: 3.774 ± 1.771
6.415SerLeu: 6.415 ± 1.019
0.755SerMet: 0.755 ± 0.398
3.019SerAsn: 3.019 ± 1.261
2.642SerPro: 2.642 ± 1.509
3.774SerGln: 3.774 ± 0.897
3.396SerArg: 3.396 ± 2.095
6.415SerSer: 6.415 ± 1.961
7.17SerThr: 7.17 ± 1.916
3.019SerVal: 3.019 ± 1.012
0.377SerTrp: 0.377 ± 0.216
1.132SerTyr: 1.132 ± 0.647
0.0SerXaa: 0.0 ± 0.0
Thr
3.774ThrAla: 3.774 ± 1.054
0.755ThrCys: 0.755 ± 0.442
6.038ThrAsp: 6.038 ± 0.995
3.019ThrGlu: 3.019 ± 1.132
3.774ThrPhe: 3.774 ± 0.679
2.642ThrGly: 2.642 ± 0.891
4.151ThrHis: 4.151 ± 1.88
4.528ThrIle: 4.528 ± 1.105
2.642ThrLys: 2.642 ± 1.087
11.321ThrLeu: 11.321 ± 2.982
0.377ThrMet: 0.377 ± 0.216
3.774ThrAsn: 3.774 ± 1.291
4.906ThrPro: 4.906 ± 0.702
6.038ThrGln: 6.038 ± 1.496
4.906ThrArg: 4.906 ± 2.105
5.283ThrSer: 5.283 ± 1.145
8.302ThrThr: 8.302 ± 2.23
3.774ThrVal: 3.774 ± 0.651
0.0ThrTrp: 0.0 ± 0.0
1.887ThrTyr: 1.887 ± 0.777
0.0ThrXaa: 0.0 ± 0.0
Val
3.396ValAla: 3.396 ± 0.917
1.132ValCys: 1.132 ± 1.084
1.887ValAsp: 1.887 ± 0.777
2.642ValGlu: 2.642 ± 0.59
1.887ValPhe: 1.887 ± 1.078
2.642ValGly: 2.642 ± 1.153
1.509ValHis: 1.509 ± 0.69
3.019ValIle: 3.019 ± 0.874
3.774ValLys: 3.774 ± 1.435
4.528ValLeu: 4.528 ± 1.015
0.377ValMet: 0.377 ± 0.216
1.887ValAsn: 1.887 ± 1.103
3.396ValPro: 3.396 ± 0.911
3.396ValGln: 3.396 ± 1.041
1.132ValArg: 1.132 ± 0.647
2.642ValSer: 2.642 ± 1.6
5.283ValThr: 5.283 ± 1.08
1.887ValVal: 1.887 ± 0.451
0.377ValTrp: 0.377 ± 0.216
1.509ValTyr: 1.509 ± 0.69
0.0ValXaa: 0.0 ± 0.0
Trp
1.132TrpAla: 1.132 ± 0.983
0.377TrpCys: 0.377 ± 0.466
0.377TrpAsp: 0.377 ± 0.216
0.0TrpGlu: 0.0 ± 0.0
0.377TrpPhe: 0.377 ± 0.216
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.755TrpLys: 0.755 ± 0.431
0.755TrpLeu: 0.755 ± 0.387
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.755TrpPro: 0.755 ± 0.387
0.0TrpGln: 0.0 ± 0.0
0.377TrpArg: 0.377 ± 0.216
0.755TrpSer: 0.755 ± 0.431
0.377TrpThr: 0.377 ± 0.216
1.132TrpVal: 1.132 ± 0.647
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.774TyrAla: 3.774 ± 0.853
1.509TyrCys: 1.509 ± 0.722
1.887TyrAsp: 1.887 ± 0.717
0.377TyrGlu: 0.377 ± 0.216
0.377TyrPhe: 0.377 ± 0.216
2.642TyrGly: 2.642 ± 0.698
1.132TyrHis: 1.132 ± 0.698
1.132TyrIle: 1.132 ± 0.567
1.132TyrLys: 1.132 ± 0.647
4.151TyrLeu: 4.151 ± 1.177
0.377TyrMet: 0.377 ± 0.216
3.396TyrAsn: 3.396 ± 2.704
0.755TyrPro: 0.755 ± 0.431
1.887TyrGln: 1.887 ± 0.451
0.755TyrArg: 0.755 ± 0.431
0.755TyrSer: 0.755 ± 0.431
1.887TyrThr: 1.887 ± 0.522
1.132TyrVal: 1.132 ± 0.58
0.0TyrTrp: 0.0 ± 0.0
0.755TyrTyr: 0.755 ± 0.431
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2651 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski