Amino acid dipepetide frequency for Rosellinia necatrix mycoreovirus 3 (isolate W370) (RnMYRV-3) (Rosellinia anti-rot virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.016AlaAla: 4.016 ± 0.892
1.295AlaCys: 1.295 ± 0.454
3.368AlaAsp: 3.368 ± 0.623
1.943AlaGlu: 1.943 ± 0.546
2.202AlaPhe: 2.202 ± 0.645
2.202AlaGly: 2.202 ± 0.551
1.425AlaHis: 1.425 ± 0.559
4.016AlaIle: 4.016 ± 0.709
2.591AlaLys: 2.591 ± 0.702
6.347AlaLeu: 6.347 ± 0.543
2.461AlaMet: 2.461 ± 0.544
2.979AlaAsn: 2.979 ± 0.564
4.404AlaPro: 4.404 ± 0.797
2.202AlaGln: 2.202 ± 0.635
5.052AlaArg: 5.052 ± 0.55
5.959AlaSer: 5.959 ± 1.048
4.922AlaThr: 4.922 ± 0.722
5.44AlaVal: 5.44 ± 0.653
1.684AlaTrp: 1.684 ± 0.311
2.461AlaTyr: 2.461 ± 0.577
0.0AlaXaa: 0.0 ± 0.0
Cys
0.777CysAla: 0.777 ± 0.24
0.0CysCys: 0.0 ± 0.0
0.907CysAsp: 0.907 ± 0.373
0.648CysGlu: 0.648 ± 0.314
0.648CysPhe: 0.648 ± 0.318
1.943CysGly: 1.943 ± 0.572
0.259CysHis: 0.259 ± 0.163
0.518CysIle: 0.518 ± 0.183
0.259CysLys: 0.259 ± 0.255
0.648CysLeu: 0.648 ± 0.172
0.518CysMet: 0.518 ± 0.228
0.389CysAsn: 0.389 ± 0.187
1.036CysPro: 1.036 ± 0.459
0.389CysGln: 0.389 ± 0.276
1.166CysArg: 1.166 ± 0.304
1.295CysSer: 1.295 ± 0.475
1.684CysThr: 1.684 ± 0.8
1.684CysVal: 1.684 ± 0.54
0.259CysTrp: 0.259 ± 0.158
0.648CysTyr: 0.648 ± 0.248
0.0CysXaa: 0.0 ± 0.0
Asp
5.052AspAla: 5.052 ± 0.531
0.648AspCys: 0.648 ± 0.308
4.922AspAsp: 4.922 ± 1.032
4.016AspGlu: 4.016 ± 0.6
2.332AspPhe: 2.332 ± 0.494
5.052AspGly: 5.052 ± 0.438
1.813AspHis: 1.813 ± 0.365
4.534AspIle: 4.534 ± 0.492
1.425AspLys: 1.425 ± 0.255
5.052AspLeu: 5.052 ± 0.797
1.425AspMet: 1.425 ± 0.356
1.295AspAsn: 1.295 ± 0.321
3.109AspPro: 3.109 ± 0.713
1.684AspGln: 1.684 ± 0.351
2.332AspArg: 2.332 ± 0.442
4.663AspSer: 4.663 ± 1.013
3.368AspThr: 3.368 ± 0.501
6.865AspVal: 6.865 ± 0.77
1.425AspTrp: 1.425 ± 0.486
1.684AspTyr: 1.684 ± 0.423
0.0AspXaa: 0.0 ± 0.0
Glu
2.461GluAla: 2.461 ± 0.411
0.518GluCys: 0.518 ± 0.202
2.979GluAsp: 2.979 ± 0.374
2.72GluGlu: 2.72 ± 0.75
2.202GluPhe: 2.202 ± 0.722
2.461GluGly: 2.461 ± 0.447
1.166GluHis: 1.166 ± 0.278
1.813GluIle: 1.813 ± 0.705
1.554GluLys: 1.554 ± 0.577
3.886GluLeu: 3.886 ± 0.791
2.332GluMet: 2.332 ± 0.585
1.425GluAsn: 1.425 ± 0.354
0.777GluPro: 0.777 ± 0.233
1.813GluGln: 1.813 ± 0.399
3.627GluArg: 3.627 ± 0.597
3.109GluSer: 3.109 ± 0.711
1.554GluThr: 1.554 ± 0.286
3.497GluVal: 3.497 ± 0.596
1.295GluTrp: 1.295 ± 0.531
2.332GluTyr: 2.332 ± 0.371
0.0GluXaa: 0.0 ± 0.0
Phe
1.813PheAla: 1.813 ± 0.547
0.389PheCys: 0.389 ± 0.206
3.109PheAsp: 3.109 ± 0.394
2.332PheGlu: 2.332 ± 0.473
1.166PhePhe: 1.166 ± 0.428
3.497PheGly: 3.497 ± 0.771
1.425PheHis: 1.425 ± 0.453
2.073PheIle: 2.073 ± 0.44
0.648PheLys: 0.648 ± 0.238
4.145PheLeu: 4.145 ± 0.768
0.777PheMet: 0.777 ± 0.259
1.295PheAsn: 1.295 ± 0.348
2.85PhePro: 2.85 ± 0.768
1.166PheGln: 1.166 ± 0.364
3.238PheArg: 3.238 ± 0.657
5.311PheSer: 5.311 ± 0.722
2.591PheThr: 2.591 ± 0.695
3.497PheVal: 3.497 ± 0.707
0.13PheTrp: 0.13 ± 0.13
1.425PheTyr: 1.425 ± 0.366
0.0PheXaa: 0.0 ± 0.0
Gly
2.591GlyAla: 2.591 ± 0.402
0.777GlyCys: 0.777 ± 0.319
2.979GlyAsp: 2.979 ± 0.603
2.72GlyGlu: 2.72 ± 0.406
3.109GlyPhe: 3.109 ± 0.244
2.72GlyGly: 2.72 ± 0.708
1.943GlyHis: 1.943 ± 0.519
4.534GlyIle: 4.534 ± 0.962
2.461GlyLys: 2.461 ± 0.451
5.959GlyLeu: 5.959 ± 0.973
2.202GlyMet: 2.202 ± 0.41
1.554GlyAsn: 1.554 ± 0.495
2.979GlyPro: 2.979 ± 0.664
2.332GlyGln: 2.332 ± 0.46
4.275GlyArg: 4.275 ± 1.156
3.368GlySer: 3.368 ± 1.033
4.275GlyThr: 4.275 ± 0.556
7.383GlyVal: 7.383 ± 0.708
1.166GlyTrp: 1.166 ± 0.321
2.461GlyTyr: 2.461 ± 0.696
0.0GlyXaa: 0.0 ± 0.0
His
2.591HisAla: 2.591 ± 0.348
0.518HisCys: 0.518 ± 0.225
1.684HisAsp: 1.684 ± 0.388
0.777HisGlu: 0.777 ± 0.332
1.554HisPhe: 1.554 ± 0.378
2.461HisGly: 2.461 ± 0.454
0.907HisHis: 0.907 ± 0.259
1.943HisIle: 1.943 ± 0.353
0.907HisLys: 0.907 ± 0.333
2.461HisLeu: 2.461 ± 0.548
0.907HisMet: 0.907 ± 0.354
0.777HisAsn: 0.777 ± 0.205
1.684HisPro: 1.684 ± 0.488
0.648HisGln: 0.648 ± 0.345
1.425HisArg: 1.425 ± 0.374
1.943HisSer: 1.943 ± 0.508
1.425HisThr: 1.425 ± 0.604
3.109HisVal: 3.109 ± 0.768
0.518HisTrp: 0.518 ± 0.348
1.295HisTyr: 1.295 ± 0.262
0.0HisXaa: 0.0 ± 0.0
Ile
3.497IleAla: 3.497 ± 0.753
1.684IleCys: 1.684 ± 0.555
4.793IleAsp: 4.793 ± 1.158
1.943IleGlu: 1.943 ± 0.347
1.554IlePhe: 1.554 ± 0.363
3.627IleGly: 3.627 ± 0.578
1.166IleHis: 1.166 ± 0.376
2.461IleIle: 2.461 ± 0.478
2.073IleLys: 2.073 ± 0.456
4.145IleLeu: 4.145 ± 0.481
1.036IleMet: 1.036 ± 0.378
2.591IleAsn: 2.591 ± 0.492
3.238IlePro: 3.238 ± 0.673
1.425IleGln: 1.425 ± 0.524
3.756IleArg: 3.756 ± 0.595
5.699IleSer: 5.699 ± 0.784
3.756IleThr: 3.756 ± 0.989
4.534IleVal: 4.534 ± 0.73
0.389IleTrp: 0.389 ± 0.278
1.166IleTyr: 1.166 ± 0.425
0.0IleXaa: 0.0 ± 0.0
Lys
1.425LysAla: 1.425 ± 0.378
0.389LysCys: 0.389 ± 0.196
2.332LysAsp: 2.332 ± 0.456
0.907LysGlu: 0.907 ± 0.552
1.684LysPhe: 1.684 ± 0.511
1.295LysGly: 1.295 ± 0.378
1.166LysHis: 1.166 ± 0.446
1.684LysIle: 1.684 ± 0.411
1.425LysLys: 1.425 ± 0.514
2.073LysLeu: 2.073 ± 0.494
0.907LysMet: 0.907 ± 0.398
1.166LysAsn: 1.166 ± 0.355
1.036LysPro: 1.036 ± 0.381
0.777LysGln: 0.777 ± 0.366
2.073LysArg: 2.073 ± 0.45
2.073LysSer: 2.073 ± 0.614
1.295LysThr: 1.295 ± 0.461
2.073LysVal: 2.073 ± 0.316
0.389LysTrp: 0.389 ± 0.245
2.461LysTyr: 2.461 ± 0.606
0.0LysXaa: 0.0 ± 0.0
Leu
6.865LeuAla: 6.865 ± 0.967
0.777LeuCys: 0.777 ± 0.331
4.275LeuAsp: 4.275 ± 0.76
4.016LeuGlu: 4.016 ± 0.799
4.275LeuPhe: 4.275 ± 0.417
5.959LeuGly: 5.959 ± 0.374
2.073LeuHis: 2.073 ± 0.385
3.497LeuIle: 3.497 ± 0.668
2.332LeuLys: 2.332 ± 0.496
7.642LeuLeu: 7.642 ± 0.753
3.109LeuMet: 3.109 ± 0.617
4.922LeuAsn: 4.922 ± 0.536
5.052LeuPro: 5.052 ± 0.591
4.016LeuGln: 4.016 ± 0.516
6.218LeuArg: 6.218 ± 1.019
9.456LeuSer: 9.456 ± 1.018
6.736LeuThr: 6.736 ± 0.953
5.181LeuVal: 5.181 ± 1.256
0.907LeuTrp: 0.907 ± 0.294
2.073LeuTyr: 2.073 ± 0.394
0.0LeuXaa: 0.0 ± 0.0
Met
1.943MetAla: 1.943 ± 0.368
0.907MetCys: 0.907 ± 0.246
1.295MetAsp: 1.295 ± 0.316
1.295MetGlu: 1.295 ± 0.359
1.943MetPhe: 1.943 ± 0.307
1.295MetGly: 1.295 ± 0.312
0.259MetHis: 0.259 ± 0.142
2.073MetIle: 2.073 ± 0.409
0.907MetLys: 0.907 ± 0.3
2.979MetLeu: 2.979 ± 0.581
0.518MetMet: 0.518 ± 0.184
1.036MetAsn: 1.036 ± 0.345
1.943MetPro: 1.943 ± 0.539
1.036MetGln: 1.036 ± 0.295
2.073MetArg: 2.073 ± 0.414
2.591MetSer: 2.591 ± 0.58
1.684MetThr: 1.684 ± 0.473
1.813MetVal: 1.813 ± 0.503
0.259MetTrp: 0.259 ± 0.158
0.907MetTyr: 0.907 ± 0.318
0.0MetXaa: 0.0 ± 0.0
Asn
2.979AsnAla: 2.979 ± 0.516
0.518AsnCys: 0.518 ± 0.374
2.073AsnAsp: 2.073 ± 0.423
1.425AsnGlu: 1.425 ± 0.248
1.684AsnPhe: 1.684 ± 0.474
2.85AsnGly: 2.85 ± 0.758
0.777AsnHis: 0.777 ± 0.214
2.202AsnIle: 2.202 ± 0.655
0.907AsnLys: 0.907 ± 0.401
2.332AsnLeu: 2.332 ± 0.628
1.166AsnMet: 1.166 ± 0.32
1.166AsnAsn: 1.166 ± 0.555
2.202AsnPro: 2.202 ± 0.611
1.166AsnGln: 1.166 ± 0.388
1.684AsnArg: 1.684 ± 0.455
2.591AsnSer: 2.591 ± 0.431
2.461AsnThr: 2.461 ± 0.53
3.627AsnVal: 3.627 ± 0.82
0.13AsnTrp: 0.13 ± 0.132
1.425AsnTyr: 1.425 ± 0.307
0.0AsnXaa: 0.0 ± 0.0
Pro
3.756ProAla: 3.756 ± 0.751
0.518ProCys: 0.518 ± 0.221
3.627ProAsp: 3.627 ± 0.686
1.943ProGlu: 1.943 ± 0.304
2.461ProPhe: 2.461 ± 0.423
2.591ProGly: 2.591 ± 0.663
1.943ProHis: 1.943 ± 0.355
2.461ProIle: 2.461 ± 0.629
1.554ProLys: 1.554 ± 0.44
5.181ProLeu: 5.181 ± 0.666
0.907ProMet: 0.907 ± 0.341
2.202ProAsn: 2.202 ± 0.395
4.145ProPro: 4.145 ± 0.827
2.202ProGln: 2.202 ± 0.446
4.145ProArg: 4.145 ± 0.755
4.275ProSer: 4.275 ± 0.611
3.886ProThr: 3.886 ± 0.731
4.404ProVal: 4.404 ± 0.453
0.518ProTrp: 0.518 ± 0.173
1.684ProTyr: 1.684 ± 0.329
0.0ProXaa: 0.0 ± 0.0
Gln
1.943GlnAla: 1.943 ± 0.501
0.259GlnCys: 0.259 ± 0.203
1.943GlnAsp: 1.943 ± 0.486
0.518GlnGlu: 0.518 ± 0.225
1.943GlnPhe: 1.943 ± 0.467
1.813GlnGly: 1.813 ± 0.438
1.554GlnHis: 1.554 ± 0.447
2.202GlnIle: 2.202 ± 0.47
0.518GlnLys: 0.518 ± 0.277
4.534GlnLeu: 4.534 ± 0.728
0.777GlnMet: 0.777 ± 0.417
1.036GlnAsn: 1.036 ± 0.379
1.295GlnPro: 1.295 ± 0.298
2.461GlnGln: 2.461 ± 0.867
2.591GlnArg: 2.591 ± 0.678
2.332GlnSer: 2.332 ± 0.663
2.073GlnThr: 2.073 ± 0.491
2.202GlnVal: 2.202 ± 0.591
0.259GlnTrp: 0.259 ± 0.173
1.684GlnTyr: 1.684 ± 0.358
0.0GlnXaa: 0.0 ± 0.0
Arg
4.534ArgAla: 4.534 ± 0.677
1.295ArgCys: 1.295 ± 0.323
4.145ArgAsp: 4.145 ± 0.611
3.627ArgGlu: 3.627 ± 0.581
2.591ArgPhe: 2.591 ± 0.561
4.016ArgGly: 4.016 ± 0.526
2.591ArgHis: 2.591 ± 0.463
4.016ArgIle: 4.016 ± 0.78
1.813ArgLys: 1.813 ± 0.456
5.052ArgLeu: 5.052 ± 0.532
1.943ArgMet: 1.943 ± 0.497
2.461ArgAsn: 2.461 ± 0.436
3.238ArgPro: 3.238 ± 0.888
2.461ArgGln: 2.461 ± 0.745
5.181ArgArg: 5.181 ± 0.946
5.44ArgSer: 5.44 ± 0.835
3.627ArgThr: 3.627 ± 0.579
5.699ArgVal: 5.699 ± 0.957
0.907ArgTrp: 0.907 ± 0.313
3.109ArgTyr: 3.109 ± 0.684
0.0ArgXaa: 0.0 ± 0.0
Ser
5.44SerAla: 5.44 ± 0.816
1.425SerCys: 1.425 ± 0.325
5.829SerAsp: 5.829 ± 0.843
3.368SerGlu: 3.368 ± 0.673
3.368SerPhe: 3.368 ± 0.76
5.699SerGly: 5.699 ± 1.112
4.016SerHis: 4.016 ± 0.722
3.497SerIle: 3.497 ± 0.441
2.591SerLys: 2.591 ± 0.754
7.383SerLeu: 7.383 ± 1.088
1.813SerMet: 1.813 ± 0.296
1.943SerAsn: 1.943 ± 0.489
4.534SerPro: 4.534 ± 1.038
3.109SerGln: 3.109 ± 0.482
5.181SerArg: 5.181 ± 0.715
6.606SerSer: 6.606 ± 1.372
7.124SerThr: 7.124 ± 0.652
6.995SerVal: 6.995 ± 1.031
1.425SerTrp: 1.425 ± 0.464
2.979SerTyr: 2.979 ± 0.583
0.0SerXaa: 0.0 ± 0.0
Thr
5.57ThrAla: 5.57 ± 0.748
0.777ThrCys: 0.777 ± 0.324
2.591ThrAsp: 2.591 ± 0.671
2.461ThrGlu: 2.461 ± 0.425
2.591ThrPhe: 2.591 ± 0.635
3.886ThrGly: 3.886 ± 0.797
1.166ThrHis: 1.166 ± 0.371
4.793ThrIle: 4.793 ± 0.547
1.295ThrLys: 1.295 ± 0.303
5.311ThrLeu: 5.311 ± 1.096
1.943ThrMet: 1.943 ± 0.531
2.202ThrAsn: 2.202 ± 0.383
4.793ThrPro: 4.793 ± 0.759
2.332ThrGln: 2.332 ± 0.51
4.145ThrArg: 4.145 ± 0.817
6.736ThrSer: 6.736 ± 0.983
5.052ThrThr: 5.052 ± 0.692
4.793ThrVal: 4.793 ± 0.598
0.777ThrTrp: 0.777 ± 0.24
2.461ThrTyr: 2.461 ± 0.425
0.0ThrXaa: 0.0 ± 0.0
Val
5.181ValAla: 5.181 ± 0.824
2.073ValCys: 2.073 ± 0.309
6.736ValAsp: 6.736 ± 0.916
4.404ValGlu: 4.404 ± 0.582
3.109ValPhe: 3.109 ± 0.698
5.699ValGly: 5.699 ± 0.845
2.332ValHis: 2.332 ± 0.435
4.275ValIle: 4.275 ± 0.455
1.684ValLys: 1.684 ± 0.42
9.715ValLeu: 9.715 ± 1.098
1.813ValMet: 1.813 ± 0.443
2.85ValAsn: 2.85 ± 0.639
4.145ValPro: 4.145 ± 1.018
2.202ValGln: 2.202 ± 0.264
6.088ValArg: 6.088 ± 0.671
7.383ValSer: 7.383 ± 0.878
5.181ValThr: 5.181 ± 0.872
6.736ValVal: 6.736 ± 0.66
0.389ValTrp: 0.389 ± 0.167
2.85ValTyr: 2.85 ± 0.613
0.0ValXaa: 0.0 ± 0.0
Trp
0.777TrpAla: 0.777 ± 0.288
0.0TrpCys: 0.0 ± 0.0
0.259TrpAsp: 0.259 ± 0.164
0.518TrpGlu: 0.518 ± 0.172
1.166TrpPhe: 1.166 ± 0.347
0.777TrpGly: 0.777 ± 0.258
0.648TrpHis: 0.648 ± 0.271
1.036TrpIle: 1.036 ± 0.304
1.036TrpLys: 1.036 ± 0.363
1.166TrpLeu: 1.166 ± 0.553
0.518TrpMet: 0.518 ± 0.231
0.907TrpAsn: 0.907 ± 0.343
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.907TrpArg: 0.907 ± 0.294
1.295TrpSer: 1.295 ± 0.321
0.907TrpThr: 0.907 ± 0.339
0.518TrpVal: 0.518 ± 0.16
0.0TrpTrp: 0.0 ± 0.0
0.518TrpTyr: 0.518 ± 0.16
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.756TyrAla: 3.756 ± 0.935
0.907TyrCys: 0.907 ± 0.209
2.979TyrAsp: 2.979 ± 0.523
1.943TyrGlu: 1.943 ± 0.243
1.295TyrPhe: 1.295 ± 0.407
1.943TyrGly: 1.943 ± 0.542
0.907TyrHis: 0.907 ± 0.268
0.907TyrIle: 0.907 ± 0.343
0.648TyrLys: 0.648 ± 0.301
3.368TyrLeu: 3.368 ± 0.797
1.554TyrMet: 1.554 ± 0.487
1.166TyrAsn: 1.166 ± 0.283
1.943TyrPro: 1.943 ± 0.301
0.518TyrGln: 0.518 ± 0.224
2.591TyrArg: 2.591 ± 0.616
2.202TyrSer: 2.202 ± 0.511
2.073TyrThr: 2.073 ± 0.445
4.793TyrVal: 4.793 ± 0.798
0.13TyrTrp: 0.13 ± 0.154
0.777TyrTyr: 0.777 ± 0.28
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (7721 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski