Human T-cell leukemia virus type I

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Deltaretrovirus; Primate T-lymphotropic virus 1

Average proteome isoelectric point is 8.3

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q9QRA0|Q9QRA0_9DELA Pr55 OS=Human T-cell leukemia virus type I OX=11908 GN=gag PE=4 SV=1
MM1 pKa = 7.1GQIFSRR7 pKa = 11.84SASPIPRR14 pKa = 11.84PPRR17 pKa = 11.84GLAAHH22 pKa = 6.78HH23 pKa = 6.5WLNFLQAAYY32 pKa = 9.85RR33 pKa = 11.84LEE35 pKa = 4.84PGPSSYY41 pKa = 11.22DD42 pKa = 2.96FHH44 pKa = 7.48QLKK47 pKa = 10.4KK48 pKa = 9.78FLKK51 pKa = 9.64IALEE55 pKa = 4.29TPVWICPINYY65 pKa = 9.78SLLASLLPKK74 pKa = 10.35GYY76 pKa = 9.08PGRR79 pKa = 11.84VNEE82 pKa = 4.56ILHH85 pKa = 6.71ILIQTQAQIPSRR97 pKa = 11.84PAPPPPSSPTHH108 pKa = 6.9DD109 pKa = 4.84PPDD112 pKa = 4.45SDD114 pKa = 3.85PQIPPPYY121 pKa = 9.76VEE123 pKa = 3.98PTAPQVLPVMHH134 pKa = 6.63PHH136 pKa = 6.98GAPPNHH142 pKa = 6.93RR143 pKa = 11.84PWQMKK148 pKa = 9.69DD149 pKa = 2.99LQAIKK154 pKa = 10.71QEE156 pKa = 4.25VSQAAPGSPQFMQTIRR172 pKa = 11.84LAVQQFDD179 pKa = 3.87PTAKK183 pKa = 10.47DD184 pKa = 3.57LQDD187 pKa = 3.86LLQYY191 pKa = 10.75LCSSLVASLHH201 pKa = 5.42HH202 pKa = 5.87QQLDD206 pKa = 3.83SLISEE211 pKa = 4.46AEE213 pKa = 3.97TRR215 pKa = 11.84GITGYY220 pKa = 10.89NPLAGPLRR228 pKa = 11.84VQANNPQQQGLRR240 pKa = 11.84RR241 pKa = 11.84EE242 pKa = 4.26YY243 pKa = 9.9QQLWLAAFAALPGSAKK259 pKa = 10.5DD260 pKa = 3.88PSWASILQGLEE271 pKa = 3.81EE272 pKa = 4.99PYY274 pKa = 10.27HH275 pKa = 6.84AFVEE279 pKa = 4.37RR280 pKa = 11.84LNIALDD286 pKa = 3.48NGLPEE291 pKa = 4.72GTPKK295 pKa = 11.01DD296 pKa = 3.86PILRR300 pKa = 11.84SLAYY304 pKa = 10.58SNANKK309 pKa = 9.97EE310 pKa = 4.36CQKK313 pKa = 10.72LLQARR318 pKa = 11.84GHH320 pKa = 5.64TNSPLGDD327 pKa = 3.73MLRR330 pKa = 11.84ACQTWTPKK338 pKa = 10.94DD339 pKa = 3.35KK340 pKa = 11.09TKK342 pKa = 11.14VLVVQPKK349 pKa = 9.84KK350 pKa = 10.29PPPNQPCFRR359 pKa = 11.84CGKK362 pKa = 9.0AGHH365 pKa = 6.84WSRR368 pKa = 11.84DD369 pKa = 3.59CTQPRR374 pKa = 11.84PPPGPCPLCQDD385 pKa = 3.33PTHH388 pKa = 7.23WKK390 pKa = 9.79RR391 pKa = 11.84DD392 pKa = 3.78CPRR395 pKa = 11.84LKK397 pKa = 9.7PTIPEE402 pKa = 4.22PEE404 pKa = 4.26PEE406 pKa = 4.01EE407 pKa = 4.68DD408 pKa = 5.51ALLLDD413 pKa = 4.9LPTDD417 pKa = 3.5IPHH420 pKa = 7.28PKK422 pKa = 9.25NLHH425 pKa = 5.93RR426 pKa = 11.84GGPPTLQQVLPNQDD440 pKa = 3.5PASILPVIPLDD451 pKa = 3.43PARR454 pKa = 11.84RR455 pKa = 11.84PVIKK459 pKa = 10.44AQVDD463 pKa = 3.92TQTSHH468 pKa = 7.24PKK470 pKa = 9.78TIEE473 pKa = 3.9ALLDD477 pKa = 3.16TGADD481 pKa = 3.45MTVLPIALFSSNTPLKK497 pKa = 8.74NTSVLGAGGQTQDD510 pKa = 3.23HH511 pKa = 6.83FKK513 pKa = 10.1LTSLPVLIRR522 pKa = 11.84LPFRR526 pKa = 11.84TTPIVLTSCLVDD538 pKa = 3.61TKK540 pKa = 11.41NNWAIIGRR548 pKa = 11.84DD549 pKa = 3.68ALQQCQGVLYY559 pKa = 10.32LPEE562 pKa = 5.01AKK564 pKa = 9.97GPPVILPIQAPAVLGLEE581 pKa = 4.13HH582 pKa = 7.29LPRR585 pKa = 11.84PPEE588 pKa = 3.87ISQFPLNQNASRR600 pKa = 11.84PCNTWSGRR608 pKa = 11.84PWRR611 pKa = 11.84QAISNPTPGQEE622 pKa = 3.39ITQYY626 pKa = 10.52SQLKK630 pKa = 9.83RR631 pKa = 11.84PMEE634 pKa = 4.85PGDD637 pKa = 3.64SSTTCGPLTLL647 pKa = 4.79

Molecular weight: 71.26 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q9QR97|Q9QR97_9DELA p40 OS=Human T-cell leukemia virus type I OX=11908 GN=tax PE=3 SV=1
MM1 pKa = 7.51GKK3 pKa = 9.97FLTTLILFFQFCPLILGDD21 pKa = 4.58YY22 pKa = 10.57SPSCCTLTIGVSSYY36 pKa = 10.86HH37 pKa = 6.73SKK39 pKa = 10.17PCNPAQPVCSWTLDD53 pKa = 3.88LLALSADD60 pKa = 3.67QALQPPCPNLVGYY73 pKa = 10.13SSYY76 pKa = 10.77HH77 pKa = 4.75ATYY80 pKa = 10.81SLYY83 pKa = 10.83LFPHH87 pKa = 7.5WIKK90 pKa = 10.78KK91 pKa = 8.39PNRR94 pKa = 11.84NGGGYY99 pKa = 10.33YY100 pKa = 9.83SASYY104 pKa = 10.97SDD106 pKa = 4.19PCSLKK111 pKa = 10.57CPYY114 pKa = 10.0LGCQSWTCPYY124 pKa = 8.96TGAVSSPYY132 pKa = 9.8WKK134 pKa = 10.19FQQDD138 pKa = 3.56VNFTQEE144 pKa = 3.75VSRR147 pKa = 11.84LNINLHH153 pKa = 5.46FSKK156 pKa = 10.67CGFSLLPSSRR166 pKa = 11.84RR167 pKa = 11.84SRR169 pKa = 11.84II170 pKa = 3.3

Molecular weight: 19.04 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

3068

170

1273

511.3

56.82

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.812 ± 0.445

2.379 ± 0.437

3.716 ± 0.27

2.803 ± 0.296

3.194 ± 0.414

5.28 ± 0.315

3.585 ± 0.278

4.889 ± 0.174

3.944 ± 0.225

12.907 ± 0.566

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.141 ± 0.128

3.162 ± 0.207

12.581 ± 0.806

7.236 ± 0.407

4.857 ± 0.239

6.845 ± 0.573

6.389 ± 0.495

3.814 ± 0.173

1.793 ± 0.093

2.673 ± 0.457
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski