Amino acid dipepetide frequency for Shahe tombus-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.001AlaAla: 7.001 ± 5.41
1.167AlaCys: 1.167 ± 2.388
7.001AlaAsp: 7.001 ± 5.41
5.834AlaGlu: 5.834 ± 0.05
3.501AlaPhe: 3.501 ± 1.753
3.501AlaGly: 3.501 ± 1.753
2.334AlaHis: 2.334 ± 1.169
1.167AlaIle: 1.167 ± 2.388
8.168AlaLys: 8.168 ± 1.854
5.834AlaLeu: 5.834 ± 0.05
0.0AlaMet: 0.0 ± 0.0
7.001AlaAsn: 7.001 ± 5.41
1.167AlaPro: 1.167 ± 0.584
0.0AlaGln: 0.0 ± 0.0
7.001AlaArg: 7.001 ± 2.438
12.835AlaSer: 12.835 ± 0.484
2.334AlaThr: 2.334 ± 1.803
8.168AlaVal: 8.168 ± 7.797
0.0AlaTrp: 0.0 ± 0.0
1.167AlaTyr: 1.167 ± 0.584
0.0AlaXaa: 0.0 ± 0.0
Cys
2.334CysAla: 2.334 ± 1.803
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.167CysGlu: 1.167 ± 0.584
0.0CysPhe: 0.0 ± 0.0
2.334CysGly: 2.334 ± 1.169
0.0CysHis: 0.0 ± 0.0
1.167CysIle: 1.167 ± 2.388
0.0CysLys: 0.0 ± 0.0
2.334CysLeu: 2.334 ± 1.169
1.167CysMet: 1.167 ± 0.584
0.0CysAsn: 0.0 ± 0.0
2.334CysPro: 2.334 ± 1.169
2.334CysGln: 2.334 ± 1.169
1.167CysArg: 1.167 ± 0.584
1.167CysSer: 1.167 ± 0.584
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
8.168AspAla: 8.168 ± 1.854
1.167AspCys: 1.167 ± 0.584
3.501AspAsp: 3.501 ± 1.753
1.167AspGlu: 1.167 ± 0.584
2.334AspPhe: 2.334 ± 1.803
5.834AspGly: 5.834 ± 3.022
0.0AspHis: 0.0 ± 0.0
2.334AspIle: 2.334 ± 1.803
3.501AspLys: 3.501 ± 1.219
2.334AspLeu: 2.334 ± 1.803
1.167AspMet: 1.167 ± 0.584
3.501AspAsn: 3.501 ± 1.219
3.501AspPro: 3.501 ± 1.753
1.167AspGln: 1.167 ± 0.584
0.0AspArg: 0.0 ± 0.0
3.501AspSer: 3.501 ± 1.219
3.501AspThr: 3.501 ± 1.753
4.667AspVal: 4.667 ± 2.337
0.0AspTrp: 0.0 ± 0.0
3.501AspTyr: 3.501 ± 1.753
0.0AspXaa: 0.0 ± 0.0
Glu
4.667GluAla: 4.667 ± 0.635
0.0GluCys: 0.0 ± 0.0
4.667GluAsp: 4.667 ± 0.635
4.667GluGlu: 4.667 ± 2.337
3.501GluPhe: 3.501 ± 1.219
2.334GluGly: 2.334 ± 1.803
2.334GluHis: 2.334 ± 1.169
2.334GluIle: 2.334 ± 1.169
1.167GluLys: 1.167 ± 0.584
4.667GluLeu: 4.667 ± 2.337
1.167GluMet: 1.167 ± 0.584
0.0GluAsn: 0.0 ± 0.0
1.167GluPro: 1.167 ± 0.584
4.667GluGln: 4.667 ± 2.337
2.334GluArg: 2.334 ± 1.169
1.167GluSer: 1.167 ± 2.388
0.0GluThr: 0.0 ± 0.0
3.501GluVal: 3.501 ± 1.219
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.334PheAla: 2.334 ± 1.169
2.334PheCys: 2.334 ± 1.169
2.334PheAsp: 2.334 ± 1.169
1.167PheGlu: 1.167 ± 0.584
0.0PhePhe: 0.0 ± 0.0
5.834PheGly: 5.834 ± 3.022
0.0PheHis: 0.0 ± 0.0
1.167PheIle: 1.167 ± 0.584
1.167PheLys: 1.167 ± 0.584
2.334PheLeu: 2.334 ± 1.169
0.0PheMet: 0.0 ± 0.0
1.167PheAsn: 1.167 ± 0.584
0.0PhePro: 0.0 ± 0.0
2.334PheGln: 2.334 ± 1.169
1.167PheArg: 1.167 ± 0.584
1.167PheSer: 1.167 ± 2.388
2.334PheThr: 2.334 ± 1.803
1.167PheVal: 1.167 ± 0.584
1.167PheTrp: 1.167 ± 2.388
3.501PheTyr: 3.501 ± 1.753
0.0PheXaa: 0.0 ± 0.0
Gly
7.001GlyAla: 7.001 ± 0.534
2.334GlyCys: 2.334 ± 1.169
3.501GlyAsp: 3.501 ± 1.753
2.334GlyGlu: 2.334 ± 1.803
3.501GlyPhe: 3.501 ± 1.753
11.669GlyGly: 11.669 ± 0.101
0.0GlyHis: 0.0 ± 0.0
3.501GlyIle: 3.501 ± 1.753
1.167GlyLys: 1.167 ± 0.584
10.502GlyLeu: 10.502 ± 2.287
8.168GlyMet: 8.168 ± 0.919
4.667GlyAsn: 4.667 ± 2.337
5.834GlyPro: 5.834 ± 2.922
1.167GlyGln: 1.167 ± 0.584
3.501GlyArg: 3.501 ± 1.219
7.001GlySer: 7.001 ± 3.506
5.834GlyThr: 5.834 ± 3.022
3.501GlyVal: 3.501 ± 1.219
1.167GlyTrp: 1.167 ± 2.388
1.167GlyTyr: 1.167 ± 0.584
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.167HisAsp: 1.167 ± 0.584
1.167HisGlu: 1.167 ± 0.584
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.167HisLys: 1.167 ± 2.388
3.501HisLeu: 3.501 ± 1.219
1.167HisMet: 1.167 ± 0.584
1.167HisAsn: 1.167 ± 0.584
2.334HisPro: 2.334 ± 1.169
1.167HisGln: 1.167 ± 0.584
0.0HisArg: 0.0 ± 0.0
1.167HisSer: 1.167 ± 0.584
2.334HisThr: 2.334 ± 1.169
1.167HisVal: 1.167 ± 0.584
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
7.001IleAla: 7.001 ± 0.534
1.167IleCys: 1.167 ± 0.584
4.667IleAsp: 4.667 ± 0.635
2.334IleGlu: 2.334 ± 1.169
0.0IlePhe: 0.0 ± 0.0
4.667IleGly: 4.667 ± 0.635
1.167IleHis: 1.167 ± 0.584
1.167IleIle: 1.167 ± 2.388
0.0IleLys: 0.0 ± 0.0
0.0IleLeu: 0.0 ± 0.0
1.167IleMet: 1.167 ± 0.584
1.167IleAsn: 1.167 ± 0.584
1.167IlePro: 1.167 ± 0.584
2.334IleGln: 2.334 ± 1.169
3.501IleArg: 3.501 ± 4.191
0.0IleSer: 0.0 ± 0.0
2.334IleThr: 2.334 ± 1.169
3.501IleVal: 3.501 ± 1.219
2.334IleTrp: 2.334 ± 1.169
2.334IleTyr: 2.334 ± 1.169
0.0IleXaa: 0.0 ± 0.0
Lys
7.001LysAla: 7.001 ± 2.438
0.0LysCys: 0.0 ± 0.0
2.334LysAsp: 2.334 ± 1.169
1.167LysGlu: 1.167 ± 2.388
0.0LysPhe: 0.0 ± 0.0
4.667LysGly: 4.667 ± 2.337
2.334LysHis: 2.334 ± 1.803
3.501LysIle: 3.501 ± 1.219
3.501LysLys: 3.501 ± 1.219
5.834LysLeu: 5.834 ± 3.022
1.167LysMet: 1.167 ± 0.731
0.0LysAsn: 0.0 ± 0.0
4.667LysPro: 4.667 ± 2.337
2.334LysGln: 2.334 ± 1.803
2.334LysArg: 2.334 ± 1.803
2.334LysSer: 2.334 ± 1.169
2.334LysThr: 2.334 ± 1.169
3.501LysVal: 3.501 ± 1.219
2.334LysTrp: 2.334 ± 4.775
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.168LeuAla: 8.168 ± 1.854
2.334LeuCys: 2.334 ± 1.169
3.501LeuAsp: 3.501 ± 1.219
0.0LeuGlu: 0.0 ± 0.0
2.334LeuPhe: 2.334 ± 1.169
7.001LeuGly: 7.001 ± 3.506
1.167LeuHis: 1.167 ± 0.584
7.001LeuIle: 7.001 ± 3.506
2.334LeuLys: 2.334 ± 1.169
1.167LeuLeu: 1.167 ± 0.584
1.167LeuMet: 1.167 ± 2.388
2.334LeuAsn: 2.334 ± 1.169
3.501LeuPro: 3.501 ± 1.219
2.334LeuGln: 2.334 ± 1.169
5.834LeuArg: 5.834 ± 2.922
5.834LeuSer: 5.834 ± 0.05
5.834LeuThr: 5.834 ± 3.022
3.501LeuVal: 3.501 ± 4.191
0.0LeuTrp: 0.0 ± 0.0
1.167LeuTyr: 1.167 ± 0.584
0.0LeuXaa: 0.0 ± 0.0
Met
3.501MetAla: 3.501 ± 4.191
1.167MetCys: 1.167 ± 0.584
1.167MetAsp: 1.167 ± 0.584
1.167MetGlu: 1.167 ± 0.584
1.167MetPhe: 1.167 ± 0.584
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.167MetIle: 1.167 ± 0.584
4.667MetLys: 4.667 ± 0.635
1.167MetLeu: 1.167 ± 0.584
0.0MetMet: 0.0 ± 0.0
1.167MetAsn: 1.167 ± 0.584
2.334MetPro: 2.334 ± 1.169
0.0MetGln: 0.0 ± 0.0
1.167MetArg: 1.167 ± 0.584
2.334MetSer: 2.334 ± 1.169
3.501MetThr: 3.501 ± 1.753
2.334MetVal: 2.334 ± 1.169
1.167MetTrp: 1.167 ± 0.584
1.167MetTyr: 1.167 ± 0.584
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
2.334AsnCys: 2.334 ± 1.169
2.334AsnAsp: 2.334 ± 4.775
0.0AsnGlu: 0.0 ± 0.0
2.334AsnPhe: 2.334 ± 1.803
3.501AsnGly: 3.501 ± 1.753
1.167AsnHis: 1.167 ± 2.388
1.167AsnIle: 1.167 ± 0.584
0.0AsnLys: 0.0 ± 0.0
3.501AsnLeu: 3.501 ± 1.753
2.334AsnMet: 2.334 ± 1.169
3.501AsnAsn: 3.501 ± 1.753
2.334AsnPro: 2.334 ± 1.803
1.167AsnGln: 1.167 ± 0.584
1.167AsnArg: 1.167 ± 0.584
3.501AsnSer: 3.501 ± 1.753
5.834AsnThr: 5.834 ± 0.05
2.334AsnVal: 2.334 ± 1.803
1.167AsnTrp: 1.167 ± 0.584
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
7.001ProAla: 7.001 ± 2.438
1.167ProCys: 1.167 ± 0.584
4.667ProAsp: 4.667 ± 2.337
1.167ProGlu: 1.167 ± 0.584
0.0ProPhe: 0.0 ± 0.0
4.667ProGly: 4.667 ± 2.337
0.0ProHis: 0.0 ± 0.0
2.334ProIle: 2.334 ± 1.169
1.167ProLys: 1.167 ± 0.584
2.334ProLeu: 2.334 ± 1.169
0.0ProMet: 0.0 ± 0.0
1.167ProAsn: 1.167 ± 2.388
2.334ProPro: 2.334 ± 1.169
1.167ProGln: 1.167 ± 2.388
5.834ProArg: 5.834 ± 2.922
3.501ProSer: 3.501 ± 1.753
8.168ProThr: 8.168 ± 1.854
7.001ProVal: 7.001 ± 0.534
2.334ProTrp: 2.334 ± 1.803
3.501ProTyr: 3.501 ± 1.219
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.167GlnGlu: 1.167 ± 0.584
2.334GlnPhe: 2.334 ± 1.169
2.334GlnGly: 2.334 ± 1.169
2.334GlnHis: 2.334 ± 1.169
4.667GlnIle: 4.667 ± 0.635
3.501GlnLys: 3.501 ± 4.191
2.334GlnLeu: 2.334 ± 1.169
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.501GlnPro: 3.501 ± 1.219
1.167GlnGln: 1.167 ± 0.584
3.501GlnArg: 3.501 ± 1.753
3.501GlnSer: 3.501 ± 1.219
3.501GlnThr: 3.501 ± 1.753
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.334ArgAla: 2.334 ± 1.169
0.0ArgCys: 0.0 ± 0.0
4.667ArgAsp: 4.667 ± 2.337
2.334ArgGlu: 2.334 ± 1.169
1.167ArgPhe: 1.167 ± 0.584
5.834ArgGly: 5.834 ± 0.05
1.167ArgHis: 1.167 ± 0.584
1.167ArgIle: 1.167 ± 0.584
3.501ArgLys: 3.501 ± 4.191
3.501ArgLeu: 3.501 ± 1.219
1.167ArgMet: 1.167 ± 0.584
2.334ArgAsn: 2.334 ± 1.803
2.334ArgPro: 2.334 ± 1.169
0.0ArgGln: 0.0 ± 0.0
4.667ArgArg: 4.667 ± 3.607
1.167ArgSer: 1.167 ± 0.584
1.167ArgThr: 1.167 ± 2.388
10.502ArgVal: 10.502 ± 2.287
5.834ArgTrp: 5.834 ± 2.922
3.501ArgTyr: 3.501 ± 1.753
0.0ArgXaa: 0.0 ± 0.0
Ser
2.334SerAla: 2.334 ± 1.169
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
4.667SerGlu: 4.667 ± 3.607
1.167SerPhe: 1.167 ± 0.584
8.168SerGly: 8.168 ± 1.118
0.0SerHis: 0.0 ± 0.0
3.501SerIle: 3.501 ± 1.753
4.667SerLys: 4.667 ± 0.635
1.167SerLeu: 1.167 ± 0.584
1.167SerMet: 1.167 ± 0.584
2.334SerAsn: 2.334 ± 1.169
2.334SerPro: 2.334 ± 1.803
2.334SerGln: 2.334 ± 1.803
2.334SerArg: 2.334 ± 1.169
5.834SerSer: 5.834 ± 2.922
7.001SerThr: 7.001 ± 3.506
9.335SerVal: 9.335 ± 1.269
3.501SerTrp: 3.501 ± 1.753
3.501SerTyr: 3.501 ± 1.753
0.0SerXaa: 0.0 ± 0.0
Thr
5.834ThrAla: 5.834 ± 0.05
1.167ThrCys: 1.167 ± 0.584
1.167ThrAsp: 1.167 ± 2.388
1.167ThrGlu: 1.167 ± 0.584
5.834ThrPhe: 5.834 ± 0.05
4.667ThrGly: 4.667 ± 0.635
0.0ThrHis: 0.0 ± 0.0
2.334ThrIle: 2.334 ± 1.803
3.501ThrLys: 3.501 ± 1.219
2.334ThrLeu: 2.334 ± 1.169
3.501ThrMet: 3.501 ± 1.753
4.667ThrAsn: 4.667 ± 2.337
7.001ThrPro: 7.001 ± 0.534
2.334ThrGln: 2.334 ± 1.169
4.667ThrArg: 4.667 ± 0.635
3.501ThrSer: 3.501 ± 1.753
4.667ThrThr: 4.667 ± 2.337
9.335ThrVal: 9.335 ± 1.269
2.334ThrTrp: 2.334 ± 1.169
2.334ThrTyr: 2.334 ± 1.169
0.0ThrXaa: 0.0 ± 0.0
Val
8.168ValAla: 8.168 ± 7.797
0.0ValCys: 0.0 ± 0.0
4.667ValAsp: 4.667 ± 0.635
3.501ValGlu: 3.501 ± 1.219
1.167ValPhe: 1.167 ± 0.584
8.168ValGly: 8.168 ± 4.09
1.167ValHis: 1.167 ± 0.584
1.167ValIle: 1.167 ± 0.584
4.667ValLys: 4.667 ± 3.607
7.001ValLeu: 7.001 ± 5.41
3.501ValMet: 3.501 ± 1.753
0.0ValAsn: 0.0 ± 0.0
10.502ValPro: 10.502 ± 3.657
2.334ValGln: 2.334 ± 1.803
4.667ValArg: 4.667 ± 2.337
5.834ValSer: 5.834 ± 0.05
5.834ValThr: 5.834 ± 2.922
5.834ValVal: 5.834 ± 0.05
1.167ValTrp: 1.167 ± 0.584
4.667ValTyr: 4.667 ± 3.607
0.0ValXaa: 0.0 ± 0.0
Trp
2.334TrpAla: 2.334 ± 4.775
1.167TrpCys: 1.167 ± 2.388
1.167TrpAsp: 1.167 ± 0.584
3.501TrpGlu: 3.501 ± 1.753
2.334TrpPhe: 2.334 ± 1.803
2.334TrpGly: 2.334 ± 1.169
1.167TrpHis: 1.167 ± 0.584
1.167TrpIle: 1.167 ± 0.584
1.167TrpLys: 1.167 ± 0.584
2.334TrpLeu: 2.334 ± 1.169
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.167TrpPro: 1.167 ± 2.388
1.167TrpGln: 1.167 ± 0.584
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
2.334TrpVal: 2.334 ± 1.169
0.0TrpTrp: 0.0 ± 0.0
1.167TrpTyr: 1.167 ± 0.584
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
2.334TyrAsp: 2.334 ± 1.169
4.667TyrGlu: 4.667 ± 2.337
0.0TyrPhe: 0.0 ± 0.0
0.0TyrGly: 0.0 ± 0.0
1.167TyrHis: 1.167 ± 0.584
0.0TyrIle: 0.0 ± 0.0
3.501TyrLys: 3.501 ± 1.753
2.334TyrLeu: 2.334 ± 1.169
1.167TyrMet: 1.167 ± 0.584
3.501TyrAsn: 3.501 ± 1.219
0.0TyrPro: 0.0 ± 0.0
2.334TyrGln: 2.334 ± 1.803
3.501TyrArg: 3.501 ± 1.753
0.0TyrSer: 0.0 ± 0.0
5.834TyrThr: 5.834 ± 2.922
2.334TyrVal: 2.334 ± 1.803
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (858 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski