Amino acid dipepetide frequency for Thiocystis violascens (strain ATCC 17096 / DSM 198 / 6111) (Chromatium violascens)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.707AlaAla: 13.707 ± 0.13
1.216AlaCys: 1.216 ± 0.033
6.779AlaAsp: 6.779 ± 0.079
7.394AlaGlu: 7.394 ± 0.084
3.719AlaPhe: 3.719 ± 0.056
9.223AlaGly: 9.223 ± 0.104
2.353AlaHis: 2.353 ± 0.047
5.906AlaIle: 5.906 ± 0.079
2.891AlaLys: 2.891 ± 0.058
13.406AlaLeu: 13.406 ± 0.136
2.944AlaMet: 2.944 ± 0.049
2.959AlaAsn: 2.959 ± 0.052
5.293AlaPro: 5.293 ± 0.082
3.908AlaGln: 3.908 ± 0.062
9.443AlaArg: 9.443 ± 0.098
6.038AlaSer: 6.038 ± 0.07
5.639AlaThr: 5.639 ± 0.07
7.645AlaVal: 7.645 ± 0.087
1.565AlaTrp: 1.565 ± 0.037
2.252AlaTyr: 2.252 ± 0.042
0.0AlaXaa: 0.0 ± 0.0
Cys
1.0CysAla: 1.0 ± 0.028
0.161CysCys: 0.161 ± 0.011
0.539CysAsp: 0.539 ± 0.02
0.584CysGlu: 0.584 ± 0.02
0.345CysPhe: 0.345 ± 0.016
0.997CysGly: 0.997 ± 0.031
0.38CysHis: 0.38 ± 0.025
0.427CysIle: 0.427 ± 0.017
0.256CysLys: 0.256 ± 0.014
1.087CysLeu: 1.087 ± 0.031
0.185CysMet: 0.185 ± 0.013
0.252CysAsn: 0.252 ± 0.014
0.63CysPro: 0.63 ± 0.024
0.366CysGln: 0.366 ± 0.016
0.811CysArg: 0.811 ± 0.023
0.488CysSer: 0.488 ± 0.02
0.435CysThr: 0.435 ± 0.02
0.696CysVal: 0.696 ± 0.026
0.14CysTrp: 0.14 ± 0.01
0.254CysTyr: 0.254 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
7.296AspAla: 7.296 ± 0.074
0.667AspCys: 0.667 ± 0.026
3.344AspAsp: 3.344 ± 0.064
3.61AspGlu: 3.61 ± 0.056
2.283AspPhe: 2.283 ± 0.044
4.943AspGly: 4.943 ± 0.073
1.258AspHis: 1.258 ± 0.03
2.691AspIle: 2.691 ± 0.051
1.41AspLys: 1.41 ± 0.035
7.358AspLeu: 7.358 ± 0.084
1.121AspMet: 1.121 ± 0.034
1.253AspAsn: 1.253 ± 0.033
4.012AspPro: 4.012 ± 0.066
2.237AspGln: 2.237 ± 0.042
4.814AspArg: 4.814 ± 0.063
2.761AspSer: 2.761 ± 0.051
2.65AspThr: 2.65 ± 0.045
3.413AspVal: 3.413 ± 0.051
1.211AspTrp: 1.211 ± 0.035
1.732AspTyr: 1.732 ± 0.04
0.0AspXaa: 0.0 ± 0.0
Glu
6.558GluAla: 6.558 ± 0.093
0.449GluCys: 0.449 ± 0.018
3.046GluAsp: 3.046 ± 0.046
3.141GluGlu: 3.141 ± 0.061
1.877GluPhe: 1.877 ± 0.037
4.021GluGly: 4.021 ± 0.058
1.423GluHis: 1.423 ± 0.034
3.702GluIle: 3.702 ± 0.056
1.698GluLys: 1.698 ± 0.044
6.577GluLeu: 6.577 ± 0.083
1.381GluMet: 1.381 ± 0.033
1.452GluAsn: 1.452 ± 0.038
3.152GluPro: 3.152 ± 0.066
3.187GluGln: 3.187 ± 0.058
6.467GluArg: 6.467 ± 0.08
3.426GluSer: 3.426 ± 0.063
4.063GluThr: 4.063 ± 0.063
3.998GluVal: 3.998 ± 0.062
0.667GluTrp: 0.667 ± 0.023
1.196GluTyr: 1.196 ± 0.027
0.0GluXaa: 0.0 ± 0.0
Phe
3.953PheAla: 3.953 ± 0.053
0.385PheCys: 0.385 ± 0.016
2.507PheAsp: 2.507 ± 0.044
2.156PheGlu: 2.156 ± 0.04
1.352PhePhe: 1.352 ± 0.038
3.129PheGly: 3.129 ± 0.049
0.788PheHis: 0.788 ± 0.023
1.515PheIle: 1.515 ± 0.034
0.969PheLys: 0.969 ± 0.029
3.512PheLeu: 3.512 ± 0.058
0.762PheMet: 0.762 ± 0.025
1.013PheAsn: 1.013 ± 0.031
1.566PhePro: 1.566 ± 0.035
1.244PheGln: 1.244 ± 0.032
2.236PheArg: 2.236 ± 0.037
2.1PheSer: 2.1 ± 0.043
1.651PheThr: 1.651 ± 0.033
2.571PheVal: 2.571 ± 0.047
0.513PheTrp: 0.513 ± 0.022
0.944PheTyr: 0.944 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
7.73GlyAla: 7.73 ± 0.092
1.073GlyCys: 1.073 ± 0.03
4.457GlyAsp: 4.457 ± 0.069
4.863GlyGlu: 4.863 ± 0.064
3.289GlyPhe: 3.289 ± 0.043
6.092GlyGly: 6.092 ± 0.096
1.917GlyHis: 1.917 ± 0.04
4.484GlyIle: 4.484 ± 0.057
2.669GlyLys: 2.669 ± 0.044
9.022GlyLeu: 9.022 ± 0.101
2.092GlyMet: 2.092 ± 0.041
2.011GlyAsn: 2.011 ± 0.055
2.771GlyPro: 2.771 ± 0.056
3.227GlyGln: 3.227 ± 0.055
5.922GlyArg: 5.922 ± 0.077
4.094GlySer: 4.094 ± 0.066
4.052GlyThr: 4.052 ± 0.069
5.703GlyVal: 5.703 ± 0.073
1.403GlyTrp: 1.403 ± 0.035
2.374GlyTyr: 2.374 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
2.512HisAla: 2.512 ± 0.04
0.3HisCys: 0.3 ± 0.016
1.27HisAsp: 1.27 ± 0.031
1.233HisGlu: 1.233 ± 0.033
0.87HisPhe: 0.87 ± 0.028
1.973HisGly: 1.973 ± 0.042
0.641HisHis: 0.641 ± 0.021
0.805HisIle: 0.805 ± 0.029
0.477HisLys: 0.477 ± 0.019
2.762HisLeu: 2.762 ± 0.045
0.399HisMet: 0.399 ± 0.018
0.462HisAsn: 0.462 ± 0.017
1.647HisPro: 1.647 ± 0.042
0.87HisGln: 0.87 ± 0.024
1.866HisArg: 1.866 ± 0.041
0.995HisSer: 0.995 ± 0.025
0.877HisThr: 0.877 ± 0.023
1.257HisVal: 1.257 ± 0.03
0.457HisTrp: 0.457 ± 0.019
0.622HisTyr: 0.622 ± 0.021
0.0HisXaa: 0.0 ± 0.0
Ile
6.543IleAla: 6.543 ± 0.079
0.494IleCys: 0.494 ± 0.016
3.573IleAsp: 3.573 ± 0.05
3.815IleGlu: 3.815 ± 0.061
1.366IlePhe: 1.366 ± 0.033
4.622IleGly: 4.622 ± 0.064
1.135IleHis: 1.135 ± 0.031
1.605IleIle: 1.605 ± 0.037
1.492IleLys: 1.492 ± 0.034
5.451IleLeu: 5.451 ± 0.076
0.784IleMet: 0.784 ± 0.024
1.359IleAsn: 1.359 ± 0.032
2.646IlePro: 2.646 ± 0.041
1.948IleGln: 1.948 ± 0.04
3.716IleArg: 3.716 ± 0.056
2.246IleSer: 2.246 ± 0.048
2.073IleThr: 2.073 ± 0.043
3.413IleVal: 3.413 ± 0.058
0.537IleTrp: 0.537 ± 0.02
1.049IleTyr: 1.049 ± 0.028
0.0IleXaa: 0.0 ± 0.0
Lys
2.902LysAla: 2.902 ± 0.055
0.195LysCys: 0.195 ± 0.012
1.516LysAsp: 1.516 ± 0.044
1.458LysGlu: 1.458 ± 0.036
0.726LysPhe: 0.726 ± 0.023
2.113LysGly: 2.113 ± 0.037
0.6LysHis: 0.6 ± 0.022
1.419LysIle: 1.419 ± 0.038
1.019LysLys: 1.019 ± 0.036
2.778LysLeu: 2.778 ± 0.047
0.543LysMet: 0.543 ± 0.02
0.753LysAsn: 0.753 ± 0.026
1.723LysPro: 1.723 ± 0.041
1.131LysGln: 1.131 ± 0.03
2.294LysArg: 2.294 ± 0.041
1.597LysSer: 1.597 ± 0.034
1.8LysThr: 1.8 ± 0.036
1.901LysVal: 1.901 ± 0.044
0.305LysTrp: 0.305 ± 0.017
0.561LysTyr: 0.561 ± 0.021
0.0LysXaa: 0.0 ± 0.0
Leu
14.729LeuAla: 14.729 ± 0.142
1.012LeuCys: 1.012 ± 0.025
7.696LeuAsp: 7.696 ± 0.085
6.863LeuGlu: 6.863 ± 0.088
3.985LeuPhe: 3.985 ± 0.056
8.815LeuGly: 8.815 ± 0.094
2.313LeuHis: 2.313 ± 0.043
6.012LeuIle: 6.012 ± 0.078
3.471LeuLys: 3.471 ± 0.057
12.526LeuLeu: 12.526 ± 0.147
2.452LeuMet: 2.452 ± 0.049
2.953LeuAsn: 2.953 ± 0.047
6.079LeuPro: 6.079 ± 0.073
3.367LeuGln: 3.367 ± 0.052
8.551LeuArg: 8.551 ± 0.093
6.395LeuSer: 6.395 ± 0.072
6.447LeuThr: 6.447 ± 0.089
7.52LeuVal: 7.52 ± 0.075
1.32LeuTrp: 1.32 ± 0.045
2.386LeuTyr: 2.386 ± 0.044
0.0LeuXaa: 0.0 ± 0.0
Met
2.463MetAla: 2.463 ± 0.049
0.141MetCys: 0.141 ± 0.01
1.307MetAsp: 1.307 ± 0.031
1.144MetGlu: 1.144 ± 0.03
0.523MetPhe: 0.523 ± 0.02
1.552MetGly: 1.552 ± 0.037
0.431MetHis: 0.431 ± 0.017
1.147MetIle: 1.147 ± 0.026
0.76MetLys: 0.76 ± 0.023
2.343MetLeu: 2.343 ± 0.052
0.506MetMet: 0.506 ± 0.019
0.824MetAsn: 0.824 ± 0.026
1.37MetPro: 1.37 ± 0.034
0.758MetGln: 0.758 ± 0.021
1.719MetArg: 1.719 ± 0.033
1.482MetSer: 1.482 ± 0.037
1.637MetThr: 1.637 ± 0.037
1.38MetVal: 1.38 ± 0.035
0.123MetTrp: 0.123 ± 0.009
0.305MetTyr: 0.305 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
2.961AsnAla: 2.961 ± 0.052
0.259AsnCys: 0.259 ± 0.015
1.36AsnAsp: 1.36 ± 0.034
1.277AsnGlu: 1.277 ± 0.033
0.792AsnPhe: 0.792 ± 0.026
2.088AsnGly: 2.088 ± 0.059
0.588AsnHis: 0.588 ± 0.022
1.106AsnIle: 1.106 ± 0.034
0.593AsnLys: 0.593 ± 0.024
3.259AsnLeu: 3.259 ± 0.047
0.479AsnMet: 0.479 ± 0.023
0.657AsnAsn: 0.657 ± 0.029
2.005AsnPro: 2.005 ± 0.043
1.041AsnGln: 1.041 ± 0.025
2.276AsnArg: 2.276 ± 0.042
1.136AsnSer: 1.136 ± 0.032
1.101AsnThr: 1.101 ± 0.034
1.554AsnVal: 1.554 ± 0.036
0.369AsnTrp: 0.369 ± 0.016
0.629AsnTyr: 0.629 ± 0.022
0.0AsnXaa: 0.0 ± 0.0
Pro
5.931ProAla: 5.931 ± 0.091
0.43ProCys: 0.43 ± 0.017
3.954ProAsp: 3.954 ± 0.057
4.217ProGlu: 4.217 ± 0.069
1.865ProPhe: 1.865 ± 0.041
4.382ProGly: 4.382 ± 0.06
0.989ProHis: 0.989 ± 0.029
2.441ProIle: 2.441 ± 0.045
1.374ProLys: 1.374 ± 0.036
5.491ProLeu: 5.491 ± 0.071
1.19ProMet: 1.19 ± 0.034
1.357ProAsn: 1.357 ± 0.031
3.051ProPro: 3.051 ± 0.064
1.498ProGln: 1.498 ± 0.037
3.413ProArg: 3.413 ± 0.059
2.919ProSer: 2.919 ± 0.042
2.726ProThr: 2.726 ± 0.048
3.94ProVal: 3.94 ± 0.057
0.816ProTrp: 0.816 ± 0.025
1.141ProTyr: 1.141 ± 0.029
0.0ProXaa: 0.0 ± 0.0
Gln
4.704GlnAla: 4.704 ± 0.062
0.333GlnCys: 0.333 ± 0.016
1.88GlnAsp: 1.88 ± 0.038
1.993GlnGlu: 1.993 ± 0.043
1.171GlnPhe: 1.171 ± 0.025
3.009GlnGly: 3.009 ± 0.054
0.774GlnHis: 0.774 ± 0.023
1.946GlnIle: 1.946 ± 0.042
0.848GlnLys: 0.848 ± 0.026
3.646GlnLeu: 3.646 ± 0.058
0.803GlnMet: 0.803 ± 0.025
0.824GlnAsn: 0.824 ± 0.028
2.075GlnPro: 2.075 ± 0.04
1.514GlnGln: 1.514 ± 0.042
3.317GlnArg: 3.317 ± 0.06
2.1GlnSer: 2.1 ± 0.036
2.149GlnThr: 2.149 ± 0.042
2.84GlnVal: 2.84 ± 0.046
0.52GlnTrp: 0.52 ± 0.019
0.72GlnTyr: 0.72 ± 0.025
0.0GlnXaa: 0.0 ± 0.0
Arg
8.259ArgAla: 8.259 ± 0.098
0.736ArgCys: 0.736 ± 0.025
4.611ArgAsp: 4.611 ± 0.066
5.348ArgGlu: 5.348 ± 0.07
3.283ArgPhe: 3.283 ± 0.048
4.883ArgGly: 4.883 ± 0.058
2.22ArgHis: 2.22 ± 0.048
4.742ArgIle: 4.742 ± 0.061
2.076ArgLys: 2.076 ± 0.044
10.373ArgLeu: 10.373 ± 0.128
1.886ArgMet: 1.886 ± 0.037
1.945ArgAsn: 1.945 ± 0.037
3.774ArgPro: 3.774 ± 0.059
3.612ArgGln: 3.612 ± 0.06
6.487ArgArg: 6.487 ± 0.093
3.384ArgSer: 3.384 ± 0.057
3.386ArgThr: 3.386 ± 0.051
5.333ArgVal: 5.333 ± 0.061
1.236ArgTrp: 1.236 ± 0.032
2.119ArgTyr: 2.119 ± 0.038
0.0ArgXaa: 0.0 ± 0.0
Ser
5.898SerAla: 5.898 ± 0.066
0.515SerCys: 0.515 ± 0.022
3.058SerAsp: 3.058 ± 0.055
3.114SerGlu: 3.114 ± 0.055
1.836SerPhe: 1.836 ± 0.034
5.034SerGly: 5.034 ± 0.081
1.174SerHis: 1.174 ± 0.03
2.462SerIle: 2.462 ± 0.044
1.328SerLys: 1.328 ± 0.033
6.175SerLeu: 6.175 ± 0.07
1.217SerMet: 1.217 ± 0.036
1.308SerAsn: 1.308 ± 0.038
2.811SerPro: 2.811 ± 0.049
1.894SerGln: 1.894 ± 0.04
3.948SerArg: 3.948 ± 0.064
2.784SerSer: 2.784 ± 0.057
2.496SerThr: 2.496 ± 0.05
3.615SerVal: 3.615 ± 0.054
0.663SerTrp: 0.663 ± 0.022
1.089SerTyr: 1.089 ± 0.028
0.0SerXaa: 0.0 ± 0.0
Thr
5.87ThrAla: 5.87 ± 0.071
0.471ThrCys: 0.471 ± 0.02
3.045ThrAsp: 3.045 ± 0.054
2.935ThrGlu: 2.935 ± 0.048
1.693ThrPhe: 1.693 ± 0.04
4.66ThrGly: 4.66 ± 0.069
1.133ThrHis: 1.133 ± 0.034
2.298ThrIle: 2.298 ± 0.038
1.072ThrLys: 1.072 ± 0.031
6.95ThrLeu: 6.95 ± 0.07
0.858ThrMet: 0.858 ± 0.025
1.25ThrAsn: 1.25 ± 0.035
3.323ThrPro: 3.323 ± 0.052
1.772ThrGln: 1.772 ± 0.043
3.594ThrArg: 3.594 ± 0.053
2.467ThrSer: 2.467 ± 0.05
2.516ThrThr: 2.516 ± 0.057
3.587ThrVal: 3.587 ± 0.064
0.633ThrTrp: 0.633 ± 0.021
1.044ThrTyr: 1.044 ± 0.031
0.0ThrXaa: 0.0 ± 0.0
Val
7.889ValAla: 7.889 ± 0.074
0.742ValCys: 0.742 ± 0.024
4.147ValAsp: 4.147 ± 0.054
4.454ValGlu: 4.454 ± 0.064
2.432ValPhe: 2.432 ± 0.04
5.009ValGly: 5.009 ± 0.066
1.348ValHis: 1.348 ± 0.033
3.589ValIle: 3.589 ± 0.057
1.994ValLys: 1.994 ± 0.044
7.197ValLeu: 7.197 ± 0.085
1.644ValMet: 1.644 ± 0.035
1.919ValAsn: 1.919 ± 0.043
3.198ValPro: 3.198 ± 0.054
2.085ValGln: 2.085 ± 0.043
4.975ValArg: 4.975 ± 0.07
3.907ValSer: 3.907 ± 0.055
3.762ValThr: 3.762 ± 0.068
4.956ValVal: 4.956 ± 0.068
0.905ValTrp: 0.905 ± 0.032
1.551ValTyr: 1.551 ± 0.032
0.0ValXaa: 0.0 ± 0.0
Trp
1.019TrpAla: 1.019 ± 0.032
0.169TrpCys: 0.169 ± 0.011
0.688TrpAsp: 0.688 ± 0.022
0.75TrpGlu: 0.75 ± 0.023
0.556TrpPhe: 0.556 ± 0.023
0.852TrpGly: 0.852 ± 0.029
0.337TrpHis: 0.337 ± 0.017
0.78TrpIle: 0.78 ± 0.022
0.42TrpLys: 0.42 ± 0.018
2.002TrpLeu: 2.002 ± 0.05
0.34TrpMet: 0.34 ± 0.015
0.422TrpAsn: 0.422 ± 0.017
0.711TrpPro: 0.711 ± 0.027
0.561TrpGln: 0.561 ± 0.021
1.343TrpArg: 1.343 ± 0.031
0.94TrpSer: 0.94 ± 0.027
0.697TrpThr: 0.697 ± 0.026
0.906TrpVal: 0.906 ± 0.025
0.249TrpTrp: 0.249 ± 0.015
0.299TrpTyr: 0.299 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.358TyrAla: 2.358 ± 0.049
0.282TyrCys: 0.282 ± 0.015
1.288TyrAsp: 1.288 ± 0.038
1.131TyrGlu: 1.131 ± 0.027
0.903TyrPhe: 0.903 ± 0.026
1.848TyrGly: 1.848 ± 0.038
0.491TyrHis: 0.491 ± 0.021
0.79TyrIle: 0.79 ± 0.024
0.515TyrLys: 0.515 ± 0.025
2.976TyrLeu: 2.976 ± 0.046
0.328TyrMet: 0.328 ± 0.015
0.558TyrAsn: 0.558 ± 0.022
1.288TyrPro: 1.288 ± 0.03
0.947TyrGln: 0.947 ± 0.028
2.502TyrArg: 2.502 ± 0.051
1.164TyrSer: 1.164 ± 0.029
1.013TyrThr: 1.013 ± 0.028
1.476TyrVal: 1.476 ± 0.035
0.411TyrTrp: 0.411 ± 0.016
0.627TyrTyr: 0.627 ± 0.022
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4192 proteins (1375469 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski