Amino acid dipepetide frequency for Arboricoccus pini

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.652AlaAla: 17.652 ± 0.169	1.238AlaCys: 1.238 ± 0.037	6.813AlaAsp: 6.813 ± 0.076	7.033AlaGlu: 7.033 ± 0.09	4.509AlaPhe: 4.509 ± 0.061	10.76AlaGly: 10.76 ± 0.111	2.365AlaHis: 2.365 ± 0.047	6.815AlaIle: 6.815 ± 0.09	3.656AlaLys: 3.656 ± 0.055	14.005AlaLeu: 14.005 ± 0.152	3.741AlaMet: 3.741 ± 0.059	2.734AlaAsn: 2.734 ± 0.054	5.356AlaPro: 5.356 ± 0.086	3.698AlaGln: 3.698 ± 0.062	9.607AlaArg: 9.607 ± 0.11	6.82AlaSer: 6.82 ± 0.081	6.325AlaThr: 6.325 ± 0.08	8.222AlaVal: 8.222 ± 0.087	1.635AlaTrp: 1.635 ± 0.039	2.667AlaTyr: 2.667 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.937CysAla: 0.937 ± 0.028	0.116CysCys: 0.116 ± 0.011	0.459CysAsp: 0.459 ± 0.02	0.403CysGlu: 0.403 ± 0.018	0.366CysPhe: 0.366 ± 0.016	0.884CysGly: 0.884 ± 0.028	0.262CysHis: 0.262 ± 0.016	0.409CysIle: 0.409 ± 0.019	0.172CysLys: 0.172 ± 0.012	1.023CysLeu: 1.023 ± 0.028	0.157CysMet: 0.157 ± 0.011	0.184CysAsn: 0.184 ± 0.012	0.456CysPro: 0.456 ± 0.02	0.276CysGln: 0.276 ± 0.015	0.736CysArg: 0.736 ± 0.027	0.453CysSer: 0.453 ± 0.022	0.414CysThr: 0.414 ± 0.018	0.572CysVal: 0.572 ± 0.023	0.127CysTrp: 0.127 ± 0.009	0.206CysTyr: 0.206 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.428AspAla: 6.428 ± 0.088	0.453AspCys: 0.453 ± 0.019	3.149AspAsp: 3.149 ± 0.059	3.493AspGlu: 3.493 ± 0.059	2.011AspPhe: 2.011 ± 0.045	4.919AspGly: 4.919 ± 0.076	1.3AspHis: 1.3 ± 0.037	2.854AspIle: 2.854 ± 0.052	1.633AspLys: 1.633 ± 0.037	6.709AspLeu: 6.709 ± 0.081	1.277AspMet: 1.277 ± 0.028	1.126AspAsn: 1.126 ± 0.031	3.747AspPro: 3.747 ± 0.057	1.844AspGln: 1.844 ± 0.036	4.71AspArg: 4.71 ± 0.064	2.077AspSer: 2.077 ± 0.044	2.277AspThr: 2.277 ± 0.05	4.029AspVal: 4.029 ± 0.059	0.908AspTrp: 0.908 ± 0.03	1.449AspTyr: 1.449 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	8.06GluAla: 8.06 ± 0.103	0.299GluCys: 0.299 ± 0.015	2.575GluAsp: 2.575 ± 0.05	3.081GluGlu: 3.081 ± 0.053	1.449GluPhe: 1.449 ± 0.031	4.515GluGly: 4.515 ± 0.069	1.114GluHis: 1.114 ± 0.03	3.254GluIle: 3.254 ± 0.051	1.646GluLys: 1.646 ± 0.042	5.852GluLeu: 5.852 ± 0.071	1.304GluMet: 1.304 ± 0.034	1.226GluAsn: 1.226 ± 0.034	2.981GluPro: 2.981 ± 0.051	2.086GluGln: 2.086 ± 0.042	5.316GluArg: 5.316 ± 0.08	2.355GluSer: 2.355 ± 0.048	3.121GluThr: 3.121 ± 0.049	3.739GluVal: 3.739 ± 0.053	0.574GluTrp: 0.574 ± 0.022	0.772GluTyr: 0.772 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.463PheAla: 4.463 ± 0.066	0.403PheCys: 0.403 ± 0.018	2.546PheAsp: 2.546 ± 0.048	2.144PheGlu: 2.144 ± 0.041	1.371PhePhe: 1.371 ± 0.039	3.295PheGly: 3.295 ± 0.054	0.706PheHis: 0.706 ± 0.025	1.715PheIle: 1.715 ± 0.04	1.257PheLys: 1.257 ± 0.034	3.481PheLeu: 3.481 ± 0.068	0.831PheMet: 0.831 ± 0.027	1.005PheAsn: 1.005 ± 0.026	1.547PhePro: 1.547 ± 0.036	0.965PheGln: 0.965 ± 0.026	1.931PheArg: 1.931 ± 0.041	1.867PheSer: 1.867 ± 0.042	1.891PheThr: 1.891 ± 0.046	2.872PheVal: 2.872 ± 0.05	0.591PheTrp: 0.591 ± 0.023	0.895PheTyr: 0.895 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	8.652GlyAla: 8.652 ± 0.093	0.877GlyCys: 0.877 ± 0.032	4.29GlyAsp: 4.29 ± 0.073	4.24GlyGlu: 4.24 ± 0.058	3.524GlyPhe: 3.524 ± 0.057	7.3GlyGly: 7.3 ± 0.091	1.886GlyHis: 1.886 ± 0.044	4.807GlyIle: 4.807 ± 0.066	3.115GlyLys: 3.115 ± 0.054	9.755GlyLeu: 9.755 ± 0.105	2.295GlyMet: 2.295 ± 0.045	1.993GlyAsn: 1.993 ± 0.053	3.835GlyPro: 3.835 ± 0.059	3.43GlyGln: 3.43 ± 0.058	7.089GlyArg: 7.089 ± 0.085	4.735GlySer: 4.735 ± 0.061	4.457GlyThr: 4.457 ± 0.08	5.81GlyVal: 5.81 ± 0.066	1.405GlyTrp: 1.405 ± 0.034	2.222GlyTyr: 2.222 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.422HisAla: 2.422 ± 0.043	0.223HisCys: 0.223 ± 0.013	1.239HisAsp: 1.239 ± 0.029	1.154HisGlu: 1.154 ± 0.031	0.815HisPhe: 0.815 ± 0.029	1.955HisGly: 1.955 ± 0.046	0.551HisHis: 0.551 ± 0.026	0.824HisIle: 0.824 ± 0.027	0.478HisLys: 0.478 ± 0.02	2.449HisLeu: 2.449 ± 0.047	0.494HisMet: 0.494 ± 0.019	0.431HisAsn: 0.431 ± 0.019	1.489HisPro: 1.489 ± 0.036	0.669HisGln: 0.669 ± 0.025	1.545HisArg: 1.545 ± 0.033	0.797HisSer: 0.797 ± 0.024	0.784HisThr: 0.784 ± 0.023	1.615HisVal: 1.615 ± 0.036	0.336HisTrp: 0.336 ± 0.015	0.557HisTyr: 0.557 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.921IleAla: 6.921 ± 0.074	0.472IleCys: 0.472 ± 0.02	3.731IleAsp: 3.731 ± 0.068	3.889IleGlu: 3.889 ± 0.064	1.798IlePhe: 1.798 ± 0.042	4.93IleGly: 4.93 ± 0.076	0.889IleHis: 0.889 ± 0.031	2.164IleIle: 2.164 ± 0.052	1.508IleLys: 1.508 ± 0.04	5.244IleLeu: 5.244 ± 0.081	1.024IleMet: 1.024 ± 0.032	1.32IleAsn: 1.32 ± 0.034	2.181IlePro: 2.181 ± 0.041	1.304IleGln: 1.304 ± 0.031	3.069IleArg: 3.069 ± 0.048	2.493IleSer: 2.493 ± 0.056	2.401IleThr: 2.401 ± 0.058	4.691IleVal: 4.691 ± 0.066	0.573IleTrp: 0.573 ± 0.022	1.079IleTyr: 1.079 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.983LysAla: 3.983 ± 0.054	0.148LysCys: 0.148 ± 0.012	1.605LysAsp: 1.605 ± 0.04	1.653LysGlu: 1.653 ± 0.047	0.679LysPhe: 0.679 ± 0.029	2.616LysGly: 2.616 ± 0.054	0.449LysHis: 0.449 ± 0.021	1.633LysIle: 1.633 ± 0.04	0.954LysLys: 0.954 ± 0.035	3.201LysLeu: 3.201 ± 0.064	0.633LysMet: 0.633 ± 0.025	0.679LysAsn: 0.679 ± 0.029	1.741LysPro: 1.741 ± 0.038	0.858LysGln: 0.858 ± 0.032	2.028LysArg: 2.028 ± 0.052	1.717LysSer: 1.717 ± 0.044	1.608LysThr: 1.608 ± 0.039	2.218LysVal: 2.218 ± 0.043	0.279LysTrp: 0.279 ± 0.014	0.443LysTyr: 0.443 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	15.647LeuAla: 15.647 ± 0.163	0.988LeuCys: 0.988 ± 0.03	6.942LeuAsp: 6.942 ± 0.082	6.107LeuGlu: 6.107 ± 0.079	3.648LeuPhe: 3.648 ± 0.066	9.385LeuGly: 9.385 ± 0.096	2.126LeuHis: 2.126 ± 0.038	5.368LeuIle: 5.368 ± 0.076	3.528LeuLys: 3.528 ± 0.064	11.355LeuLeu: 11.355 ± 0.169	2.456LeuMet: 2.456 ± 0.051	2.51LeuAsn: 2.51 ± 0.057	6.572LeuPro: 6.572 ± 0.083	3.273LeuGln: 3.273 ± 0.061	7.663LeuArg: 7.663 ± 0.085	6.147LeuSer: 6.147 ± 0.082	5.777LeuThr: 5.777 ± 0.076	8.151LeuVal: 8.151 ± 0.109	1.3LeuTrp: 1.3 ± 0.038	1.985LeuTyr: 1.985 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.461MetAla: 3.461 ± 0.056	0.136MetCys: 0.136 ± 0.009	1.068MetAsp: 1.068 ± 0.031	0.988MetGlu: 0.988 ± 0.029	0.633MetPhe: 0.633 ± 0.025	1.923MetGly: 1.923 ± 0.04	0.418MetHis: 0.418 ± 0.02	1.324MetIle: 1.324 ± 0.036	0.693MetLys: 0.693 ± 0.027	2.6MetLeu: 2.6 ± 0.055	0.588MetMet: 0.588 ± 0.026	0.605MetAsn: 0.605 ± 0.021	1.578MetPro: 1.578 ± 0.038	0.903MetGln: 0.903 ± 0.027	1.936MetArg: 1.936 ± 0.037	1.731MetSer: 1.731 ± 0.034	1.709MetThr: 1.709 ± 0.038	1.62MetVal: 1.62 ± 0.042	0.191MetTrp: 0.191 ± 0.013	0.247MetTyr: 0.247 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.779AsnAla: 2.779 ± 0.062	0.227AsnCys: 0.227 ± 0.013	1.327AsnAsp: 1.327 ± 0.032	1.254AsnGlu: 1.254 ± 0.032	0.85AsnPhe: 0.85 ± 0.029	2.137AsnGly: 2.137 ± 0.05	0.458AsnHis: 0.458 ± 0.018	1.217AsnIle: 1.217 ± 0.031	0.583AsnLys: 0.583 ± 0.024	2.548AsnLeu: 2.548 ± 0.046	0.493AsnMet: 0.493 ± 0.021	0.548AsnAsn: 0.548 ± 0.023	1.606AsnPro: 1.606 ± 0.041	0.686AsnGln: 0.686 ± 0.026	1.615AsnArg: 1.615 ± 0.034	1.109AsnSer: 1.109 ± 0.03	0.963AsnThr: 0.963 ± 0.031	1.838AsnVal: 1.838 ± 0.039	0.379AsnTrp: 0.379 ± 0.019	0.591AsnTyr: 0.591 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.835ProAla: 6.835 ± 0.088	0.366ProCys: 0.366 ± 0.019	3.526ProAsp: 3.526 ± 0.054	3.508ProGlu: 3.508 ± 0.064	2.11ProPhe: 2.11 ± 0.039	4.784ProGly: 4.784 ± 0.07	1.136ProHis: 1.136 ± 0.033	2.544ProIle: 2.544 ± 0.044	1.447ProLys: 1.447 ± 0.038	5.464ProLeu: 5.464 ± 0.076	1.323ProMet: 1.323 ± 0.036	1.26ProAsn: 1.26 ± 0.037	3.122ProPro: 3.122 ± 0.064	1.423ProGln: 1.423 ± 0.034	3.244ProArg: 3.244 ± 0.061	3.323ProSer: 3.323 ± 0.062	2.742ProThr: 2.742 ± 0.05	4.074ProVal: 4.074 ± 0.062	0.736ProTrp: 0.736 ± 0.026	1.22ProTyr: 1.22 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	4.659GlnAla: 4.659 ± 0.07	0.195GlnCys: 0.195 ± 0.012	1.681GlnAsp: 1.681 ± 0.041	1.531GlnGlu: 1.531 ± 0.042	0.935GlnPhe: 0.935 ± 0.031	2.822GlnGly: 2.822 ± 0.049	0.689GlnHis: 0.689 ± 0.022	1.725GlnIle: 1.725 ± 0.044	0.91GlnLys: 0.91 ± 0.031	3.178GlnLeu: 3.178 ± 0.057	0.779GlnMet: 0.779 ± 0.026	0.757GlnAsn: 0.757 ± 0.025	2.051GlnPro: 2.051 ± 0.042	1.236GlnGln: 1.236 ± 0.038	2.84GlnArg: 2.84 ± 0.052	1.926GlnSer: 1.926 ± 0.036	1.718GlnThr: 1.718 ± 0.047	2.188GlnVal: 2.188 ± 0.043	0.304GlnTrp: 0.304 ± 0.016	0.505GlnTyr: 0.505 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	8.338ArgAla: 8.338 ± 0.087	0.59ArgCys: 0.59 ± 0.023	3.891ArgAsp: 3.891 ± 0.064	3.999ArgGlu: 3.999 ± 0.06	3.016ArgPhe: 3.016 ± 0.048	4.847ArgGly: 4.847 ± 0.066	2.165ArgHis: 2.165 ± 0.042	3.952ArgIle: 3.952 ± 0.06	1.815ArgLys: 1.815 ± 0.038	9.928ArgLeu: 9.928 ± 0.121	1.795ArgMet: 1.795 ± 0.039	1.644ArgAsn: 1.644 ± 0.039	4.271ArgPro: 4.271 ± 0.069	3.238ArgGln: 3.238 ± 0.055	7.01ArgArg: 7.01 ± 0.097	3.788ArgSer: 3.788 ± 0.058	3.369ArgThr: 3.369 ± 0.049	4.716ArgVal: 4.716 ± 0.063	1.023ArgTrp: 1.023 ± 0.027	1.842ArgTyr: 1.842 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	5.772SerAla: 5.772 ± 0.067	0.45SerCys: 0.45 ± 0.018	2.722SerAsp: 2.722 ± 0.049	2.522SerGlu: 2.522 ± 0.046	2.36SerPhe: 2.36 ± 0.047	5.111SerGly: 5.111 ± 0.063	1.094SerHis: 1.094 ± 0.027	2.839SerIle: 2.839 ± 0.051	1.375SerLys: 1.375 ± 0.036	6.189SerLeu: 6.189 ± 0.079	1.455SerMet: 1.455 ± 0.039	1.27SerAsn: 1.27 ± 0.033	2.916SerPro: 2.916 ± 0.043	1.685SerGln: 1.685 ± 0.035	3.635SerArg: 3.635 ± 0.058	3.14SerSer: 3.14 ± 0.07	2.75SerThr: 2.75 ± 0.053	3.644SerVal: 3.644 ± 0.061	0.808SerTrp: 0.808 ± 0.026	1.33SerTyr: 1.33 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.005ThrAla: 6.005 ± 0.08	0.473ThrCys: 0.473 ± 0.022	2.522ThrAsp: 2.522 ± 0.047	2.207ThrGlu: 2.207 ± 0.042	1.931ThrPhe: 1.931 ± 0.039	4.798ThrGly: 4.798 ± 0.071	1.049ThrHis: 1.049 ± 0.029	2.967ThrIle: 2.967 ± 0.055	1.33ThrLys: 1.33 ± 0.041	5.959ThrLeu: 5.959 ± 0.073	1.197ThrMet: 1.197 ± 0.031	1.211ThrAsn: 1.211 ± 0.03	3.164ThrPro: 3.164 ± 0.055	1.42ThrGln: 1.42 ± 0.044	3.364ThrArg: 3.364 ± 0.052	3.028ThrSer: 3.028 ± 0.058	2.947ThrThr: 2.947 ± 0.052	3.732ThrVal: 3.732 ± 0.061	0.579ThrTrp: 0.579 ± 0.02	1.126ThrTyr: 1.126 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	9.002ValAla: 9.002 ± 0.103	0.609ValCys: 0.609 ± 0.023	4.394ValAsp: 4.394 ± 0.058	4.367ValGlu: 4.367 ± 0.065	2.485ValPhe: 2.485 ± 0.049	5.777ValGly: 5.777 ± 0.071	1.374ValHis: 1.374 ± 0.037	3.849ValIle: 3.849 ± 0.055	2.048ValLys: 2.048 ± 0.045	7.645ValLeu: 7.645 ± 0.09	1.785ValMet: 1.785 ± 0.037	1.768ValAsn: 1.768 ± 0.042	3.764ValPro: 3.764 ± 0.057	2.246ValGln: 2.246 ± 0.042	4.82ValArg: 4.82 ± 0.075	3.767ValSer: 3.767 ± 0.062	4.056ValThr: 4.056 ± 0.054	5.677ValVal: 5.677 ± 0.082	0.873ValTrp: 0.873 ± 0.027	1.376ValTyr: 1.376 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.173TrpAla: 1.173 ± 0.034	0.139TrpCys: 0.139 ± 0.01	0.577TrpAsp: 0.577 ± 0.026	0.521TrpGlu: 0.521 ± 0.02	0.481TrpPhe: 0.481 ± 0.021	0.853TrpGly: 0.853 ± 0.026	0.353TrpHis: 0.353 ± 0.017	0.627TrpIle: 0.627 ± 0.022	0.372TrpLys: 0.372 ± 0.022	1.87TrpLeu: 1.87 ± 0.044	0.308TrpMet: 0.308 ± 0.017	0.405TrpAsn: 0.405 ± 0.017	0.752TrpPro: 0.752 ± 0.025	0.664TrpGln: 0.664 ± 0.026	1.323TrpArg: 1.323 ± 0.033	0.821TrpSer: 0.821 ± 0.028	0.757TrpThr: 0.757 ± 0.026	0.74TrpVal: 0.74 ± 0.03	0.196TrpTrp: 0.196 ± 0.013	0.273TrpTyr: 0.273 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.463TyrAla: 2.463 ± 0.048	0.208TyrCys: 0.208 ± 0.014	1.336TyrAsp: 1.336 ± 0.038	1.225TyrGlu: 1.225 ± 0.03	0.806TyrPhe: 0.806 ± 0.026	2.11TyrGly: 2.11 ± 0.044	0.443TyrHis: 0.443 ± 0.019	0.796TyrIle: 0.796 ± 0.029	0.604TyrLys: 0.604 ± 0.027	2.468TyrLeu: 2.468 ± 0.054	0.414TyrMet: 0.414 ± 0.019	0.531TyrAsn: 0.531 ± 0.022	1.06TyrPro: 1.06 ± 0.029	0.728TyrGln: 0.728 ± 0.021	1.755TyrArg: 1.755 ± 0.041	0.972TyrSer: 0.972 ± 0.03	0.946TyrThr: 0.946 ± 0.031	1.533TyrVal: 1.533 ± 0.041	0.385TyrTrp: 0.385 ± 0.018	0.618TyrTyr: 0.618 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3717 proteins (1199682 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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