Amino acid dipepetide frequency for Tortoise microvirus 63

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.97AlaAla: 5.97 ± 1.947
1.791AlaCys: 1.791 ± 1.532
7.164AlaAsp: 7.164 ± 1.437
5.373AlaGlu: 5.373 ± 3.221
5.373AlaPhe: 5.373 ± 0.979
5.97AlaGly: 5.97 ± 2.596
0.597AlaHis: 0.597 ± 0.744
2.985AlaIle: 2.985 ± 0.989
4.776AlaLys: 4.776 ± 1.753
4.179AlaLeu: 4.179 ± 1.246
1.194AlaMet: 1.194 ± 0.672
2.388AlaAsn: 2.388 ± 1.344
5.373AlaPro: 5.373 ± 1.654
2.985AlaGln: 2.985 ± 1.298
2.388AlaArg: 2.388 ± 0.961
5.97AlaSer: 5.97 ± 2.293
5.373AlaThr: 5.373 ± 1.343
4.776AlaVal: 4.776 ± 0.96
0.0AlaTrp: 0.0 ± 0.0
1.791AlaTyr: 1.791 ± 0.415
0.0AlaXaa: 0.0 ± 0.0
Cys
1.194CysAla: 1.194 ± 1.088
0.0CysCys: 0.0 ± 0.0
1.194CysAsp: 1.194 ± 0.491
0.597CysGlu: 0.597 ± 0.744
1.194CysPhe: 1.194 ± 0.831
1.791CysGly: 1.791 ± 1.842
0.0CysHis: 0.0 ± 0.0
0.597CysIle: 0.597 ± 0.661
0.0CysLys: 0.0 ± 0.0
1.791CysLeu: 1.791 ± 1.234
0.0CysMet: 0.0 ± 0.0
0.597CysAsn: 0.597 ± 0.744
0.597CysPro: 0.597 ± 0.572
0.0CysGln: 0.0 ± 0.0
1.791CysArg: 1.791 ± 0.971
0.597CysSer: 0.597 ± 0.572
0.597CysThr: 0.597 ± 0.572
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.194CysTyr: 1.194 ± 1.088
0.0CysXaa: 0.0 ± 0.0
Asp
5.97AspAla: 5.97 ± 1.588
1.791AspCys: 1.791 ± 0.957
5.373AspAsp: 5.373 ± 1.617
2.388AspGlu: 2.388 ± 1.379
5.373AspPhe: 5.373 ± 1.711
2.985AspGly: 2.985 ± 1.228
1.194AspHis: 1.194 ± 0.882
5.97AspIle: 5.97 ± 0.695
2.985AspLys: 2.985 ± 2.332
5.97AspLeu: 5.97 ± 1.394
0.597AspMet: 0.597 ± 0.441
3.582AspAsn: 3.582 ± 2.065
1.194AspPro: 1.194 ± 0.67
2.388AspGln: 2.388 ± 1.441
1.791AspArg: 1.791 ± 1.043
6.567AspSer: 6.567 ± 1.215
4.179AspThr: 4.179 ± 0.957
4.179AspVal: 4.179 ± 1.299
0.597AspTrp: 0.597 ± 0.479
4.776AspTyr: 4.776 ± 1.323
0.0AspXaa: 0.0 ± 0.0
Glu
2.985GluAla: 2.985 ± 1.257
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
0.597GluGlu: 0.597 ± 0.479
1.194GluPhe: 1.194 ± 0.491
0.597GluGly: 0.597 ± 0.441
1.194GluHis: 1.194 ± 0.787
1.791GluIle: 1.791 ± 1.009
3.582GluLys: 3.582 ± 1.442
7.164GluLeu: 7.164 ± 1.889
2.985GluMet: 2.985 ± 1.363
1.194GluAsn: 1.194 ± 0.67
0.0GluPro: 0.0 ± 0.0
3.582GluGln: 3.582 ± 1.284
2.985GluArg: 2.985 ± 1.198
2.985GluSer: 2.985 ± 1.83
2.388GluThr: 2.388 ± 1.009
1.791GluVal: 1.791 ± 1.043
1.194GluTrp: 1.194 ± 0.986
2.388GluTyr: 2.388 ± 0.847
0.0GluXaa: 0.0 ± 0.0
Phe
7.164PheAla: 7.164 ± 1.244
1.194PheCys: 1.194 ± 1.144
4.179PheAsp: 4.179 ± 1.193
2.388PheGlu: 2.388 ± 0.844
1.791PhePhe: 1.791 ± 1.018
3.582PheGly: 3.582 ± 1.293
0.0PheHis: 0.0 ± 0.0
3.582PheIle: 3.582 ± 2.485
1.194PheLys: 1.194 ± 0.986
4.776PheLeu: 4.776 ± 1.794
0.597PheMet: 0.597 ± 0.441
3.582PheAsn: 3.582 ± 1.252
1.194PhePro: 1.194 ± 0.801
4.179PheGln: 4.179 ± 1.5
1.791PheArg: 1.791 ± 1.256
2.985PheSer: 2.985 ± 1.147
2.388PheThr: 2.388 ± 0.833
0.0PheVal: 0.0 ± 0.0
1.791PheTrp: 1.791 ± 0.788
1.791PheTyr: 1.791 ± 0.922
0.0PheXaa: 0.0 ± 0.0
Gly
2.985GlyAla: 2.985 ± 1.656
1.194GlyCys: 1.194 ± 1.088
5.97GlyAsp: 5.97 ± 2.39
1.194GlyGlu: 1.194 ± 0.672
2.985GlyPhe: 2.985 ± 0.96
2.388GlyGly: 2.388 ± 1.184
1.791GlyHis: 1.791 ± 0.415
2.985GlyIle: 2.985 ± 0.61
1.791GlyLys: 1.791 ± 1.018
7.761GlyLeu: 7.761 ± 0.809
1.194GlyMet: 1.194 ± 0.958
1.791GlyAsn: 1.791 ± 0.777
0.0GlyPro: 0.0 ± 0.0
1.194GlyGln: 1.194 ± 0.882
2.985GlyArg: 2.985 ± 0.773
10.149GlySer: 10.149 ± 1.512
4.776GlyThr: 4.776 ± 2.225
3.582GlyVal: 3.582 ± 1.303
0.597GlyTrp: 0.597 ± 0.441
4.179GlyTyr: 4.179 ± 0.845
0.0GlyXaa: 0.0 ± 0.0
His
1.194HisAla: 1.194 ± 0.814
0.597HisCys: 0.597 ± 0.572
0.597HisAsp: 0.597 ± 0.479
1.194HisGlu: 1.194 ± 0.491
1.194HisPhe: 1.194 ± 0.481
2.985HisGly: 2.985 ± 1.421
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.388HisLeu: 2.388 ± 1.519
0.0HisMet: 0.0 ± 0.0
0.597HisAsn: 0.597 ± 0.479
1.194HisPro: 1.194 ± 0.801
0.597HisGln: 0.597 ± 0.479
1.791HisArg: 1.791 ± 0.649
1.791HisSer: 1.791 ± 0.415
0.597HisThr: 0.597 ± 0.661
0.597HisVal: 0.597 ± 0.572
0.0HisTrp: 0.0 ± 0.0
0.597HisTyr: 0.597 ± 0.572
0.0HisXaa: 0.0 ± 0.0
Ile
4.776IleAla: 4.776 ± 0.933
1.194IleCys: 1.194 ± 1.086
3.582IleAsp: 3.582 ± 2.361
2.388IleGlu: 2.388 ± 1.899
1.791IlePhe: 1.791 ± 0.738
2.985IleGly: 2.985 ± 1.183
0.0IleHis: 0.0 ± 0.0
0.597IleIle: 0.597 ± 0.822
1.194IleLys: 1.194 ± 0.828
1.791IleLeu: 1.791 ± 0.922
1.194IleMet: 1.194 ± 1.106
1.791IleAsn: 1.791 ± 0.852
5.97IlePro: 5.97 ± 1.618
2.388IleGln: 2.388 ± 1.516
4.179IleArg: 4.179 ± 1.831
3.582IleSer: 3.582 ± 1.23
2.388IleThr: 2.388 ± 1.516
3.582IleVal: 3.582 ± 1.25
1.194IleTrp: 1.194 ± 0.882
2.388IleTyr: 2.388 ± 1.543
0.0IleXaa: 0.0 ± 0.0
Lys
3.582LysAla: 3.582 ± 2.524
0.597LysCys: 0.597 ± 0.661
2.985LysAsp: 2.985 ± 2.446
1.791LysGlu: 1.791 ± 0.415
1.194LysPhe: 1.194 ± 0.672
1.791LysGly: 1.791 ± 1.716
1.194LysHis: 1.194 ± 1.144
1.791LysIle: 1.791 ± 1.545
0.597LysLys: 0.597 ± 0.661
4.179LysLeu: 4.179 ± 1.446
1.791LysMet: 1.791 ± 0.746
2.985LysAsn: 2.985 ± 0.692
2.388LysPro: 2.388 ± 1.199
2.388LysGln: 2.388 ± 1.166
2.388LysArg: 2.388 ± 1.599
2.388LysSer: 2.388 ± 1.324
2.388LysThr: 2.388 ± 1.242
1.194LysVal: 1.194 ± 0.828
0.0LysTrp: 0.0 ± 0.0
1.194LysTyr: 1.194 ± 1.144
0.0LysXaa: 0.0 ± 0.0
Leu
4.776LeuAla: 4.776 ± 1.258
1.194LeuCys: 1.194 ± 0.971
7.164LeuAsp: 7.164 ± 2.246
4.179LeuGlu: 4.179 ± 1.107
4.179LeuPhe: 4.179 ± 1.52
8.358LeuGly: 8.358 ± 1.932
0.0LeuHis: 0.0 ± 0.0
5.97LeuIle: 5.97 ± 1.36
3.582LeuLys: 3.582 ± 0.734
2.985LeuLeu: 2.985 ± 1.321
2.388LeuMet: 2.388 ± 1.066
7.761LeuAsn: 7.761 ± 3.094
7.164LeuPro: 7.164 ± 2.318
4.179LeuGln: 4.179 ± 1.642
5.373LeuArg: 5.373 ± 1.362
9.552LeuSer: 9.552 ± 2.539
5.373LeuThr: 5.373 ± 1.001
0.597LeuVal: 0.597 ± 0.572
1.194LeuTrp: 1.194 ± 0.491
0.597LeuTyr: 0.597 ± 0.441
0.0LeuXaa: 0.0 ± 0.0
Met
4.179MetAla: 4.179 ± 1.75
0.0MetCys: 0.0 ± 0.0
2.985MetAsp: 2.985 ± 1.183
0.597MetGlu: 0.597 ± 0.441
1.194MetPhe: 1.194 ± 0.481
1.194MetGly: 1.194 ± 0.672
1.194MetHis: 1.194 ± 0.828
1.791MetIle: 1.791 ± 0.922
1.194MetLys: 1.194 ± 1.585
1.194MetLeu: 1.194 ± 0.958
1.791MetMet: 1.791 ± 0.771
1.194MetAsn: 1.194 ± 0.814
1.194MetPro: 1.194 ± 0.958
0.0MetGln: 0.0 ± 0.0
1.194MetArg: 1.194 ± 0.481
1.194MetSer: 1.194 ± 0.672
1.791MetThr: 1.791 ± 0.771
1.791MetVal: 1.791 ± 1.057
0.597MetTrp: 0.597 ± 0.441
3.582MetTyr: 3.582 ± 1.187
0.0MetXaa: 0.0 ± 0.0
Asn
4.179AsnAla: 4.179 ± 1.231
0.597AsnCys: 0.597 ± 0.661
4.776AsnAsp: 4.776 ± 1.602
2.388AsnGlu: 2.388 ± 1.184
2.985AsnPhe: 2.985 ± 0.773
1.791AsnGly: 1.791 ± 0.771
0.0AsnHis: 0.0 ± 0.0
1.194AsnIle: 1.194 ± 0.828
1.791AsnLys: 1.791 ± 0.738
3.582AsnLeu: 3.582 ± 1.174
1.194AsnMet: 1.194 ± 0.481
1.791AsnAsn: 1.791 ± 0.738
1.194AsnPro: 1.194 ± 0.986
2.985AsnGln: 2.985 ± 0.692
4.179AsnArg: 4.179 ± 1.999
1.791AsnSer: 1.791 ± 1.548
4.179AsnThr: 4.179 ± 1.692
3.582AsnVal: 3.582 ± 1.688
0.597AsnTrp: 0.597 ± 0.572
1.791AsnTyr: 1.791 ± 0.771
0.0AsnXaa: 0.0 ± 0.0
Pro
3.582ProAla: 3.582 ± 1.31
0.0ProCys: 0.0 ± 0.0
2.985ProAsp: 2.985 ± 1.603
1.791ProGlu: 1.791 ± 0.971
2.985ProPhe: 2.985 ± 1.145
0.597ProGly: 0.597 ± 0.479
2.388ProHis: 2.388 ± 1.496
4.179ProIle: 4.179 ± 1.26
1.194ProLys: 1.194 ± 1.044
5.373ProLeu: 5.373 ± 1.683
1.791ProMet: 1.791 ± 0.679
4.179ProAsn: 4.179 ± 2.377
2.985ProPro: 2.985 ± 1.505
3.582ProGln: 3.582 ± 0.734
0.597ProArg: 0.597 ± 0.441
7.164ProSer: 7.164 ± 1.581
4.179ProThr: 4.179 ± 1.826
4.776ProVal: 4.776 ± 1.551
0.0ProTrp: 0.0 ± 0.0
1.791ProTyr: 1.791 ± 1.324
0.0ProXaa: 0.0 ± 0.0
Gln
5.373GlnAla: 5.373 ± 2.402
0.597GlnCys: 0.597 ± 0.441
1.791GlnAsp: 1.791 ± 1.086
3.582GlnGlu: 3.582 ± 2.504
4.776GlnPhe: 4.776 ± 1.783
1.194GlnGly: 1.194 ± 0.67
1.194GlnHis: 1.194 ± 0.672
2.388GlnIle: 2.388 ± 1.203
2.985GlnLys: 2.985 ± 1.188
2.388GlnLeu: 2.388 ± 1.441
1.791GlnMet: 1.791 ± 1.437
2.388GlnAsn: 2.388 ± 0.75
1.194GlnPro: 1.194 ± 0.882
4.776GlnGln: 4.776 ± 2.591
2.388GlnArg: 2.388 ± 0.941
9.552GlnSer: 9.552 ± 2.27
0.0GlnThr: 0.0 ± 0.0
4.179GlnVal: 4.179 ± 1.164
1.194GlnTrp: 1.194 ± 0.958
0.597GlnTyr: 0.597 ± 0.479
0.0GlnXaa: 0.0 ± 0.0
Arg
1.791ArgAla: 1.791 ± 0.788
0.0ArgCys: 0.0 ± 0.0
4.179ArgAsp: 4.179 ± 0.697
4.179ArgGlu: 4.179 ± 1.464
1.791ArgPhe: 1.791 ± 0.71
3.582ArgGly: 3.582 ± 0.712
1.194ArgHis: 1.194 ± 0.672
1.791ArgIle: 1.791 ± 0.866
1.194ArgLys: 1.194 ± 1.144
5.97ArgLeu: 5.97 ± 1.904
2.388ArgMet: 2.388 ± 0.961
2.388ArgAsn: 2.388 ± 1.543
4.179ArgPro: 4.179 ± 1.903
2.985ArgGln: 2.985 ± 1.188
1.791ArgArg: 1.791 ± 0.913
3.582ArgSer: 3.582 ± 0.844
1.194ArgThr: 1.194 ± 0.481
3.582ArgVal: 3.582 ± 1.583
0.0ArgTrp: 0.0 ± 0.0
4.776ArgTyr: 4.776 ± 1.743
0.0ArgXaa: 0.0 ± 0.0
Ser
7.761SerAla: 7.761 ± 2.138
1.791SerCys: 1.791 ± 1.264
1.791SerAsp: 1.791 ± 0.866
2.985SerGlu: 2.985 ± 1.064
4.179SerPhe: 4.179 ± 1.879
8.358SerGly: 8.358 ± 1.256
0.597SerHis: 0.597 ± 0.441
5.97SerIle: 5.97 ± 1.337
4.179SerLys: 4.179 ± 1.315
6.567SerLeu: 6.567 ± 1.918
2.388SerMet: 2.388 ± 0.658
2.388SerAsn: 2.388 ± 0.961
5.373SerPro: 5.373 ± 0.825
5.373SerGln: 5.373 ± 2.367
5.97SerArg: 5.97 ± 2.403
8.358SerSer: 8.358 ± 2.991
4.776SerThr: 4.776 ± 1.473
6.567SerVal: 6.567 ± 2.108
0.597SerTrp: 0.597 ± 0.661
4.776SerTyr: 4.776 ± 1.058
0.0SerXaa: 0.0 ± 0.0
Thr
3.582ThrAla: 3.582 ± 2.647
0.0ThrCys: 0.0 ± 0.0
4.179ThrAsp: 4.179 ± 0.697
1.194ThrGlu: 1.194 ± 0.481
2.388ThrPhe: 2.388 ± 0.531
4.179ThrGly: 4.179 ± 1.546
0.597ThrHis: 0.597 ± 0.479
1.791ThrIle: 1.791 ± 1.404
1.791ThrLys: 1.791 ± 0.927
6.567ThrLeu: 6.567 ± 1.417
2.388ThrMet: 2.388 ± 1.538
1.791ThrAsn: 1.791 ± 0.788
5.373ThrPro: 5.373 ± 2.18
2.388ThrGln: 2.388 ± 0.961
1.791ThrArg: 1.791 ± 0.738
3.582ThrSer: 3.582 ± 1.065
2.388ThrThr: 2.388 ± 1.184
4.179ThrVal: 4.179 ± 0.697
0.0ThrTrp: 0.0 ± 0.0
4.179ThrTyr: 4.179 ± 1.717
0.0ThrXaa: 0.0 ± 0.0
Val
4.179ValAla: 4.179 ± 1.5
0.597ValCys: 0.597 ± 0.822
5.373ValAsp: 5.373 ± 1.536
0.597ValGlu: 0.597 ± 0.744
2.388ValPhe: 2.388 ± 1.28
2.985ValGly: 2.985 ± 0.96
2.985ValHis: 2.985 ± 1.244
1.791ValIle: 1.791 ± 0.415
2.388ValLys: 2.388 ± 1.599
7.164ValLeu: 7.164 ± 1.086
0.597ValMet: 0.597 ± 0.403
1.194ValAsn: 1.194 ± 0.787
7.164ValPro: 7.164 ± 1.747
3.582ValGln: 3.582 ± 1.714
3.582ValArg: 3.582 ± 1.732
2.985ValSer: 2.985 ± 0.93
1.791ValThr: 1.791 ± 0.853
2.388ValVal: 2.388 ± 1.443
0.0ValTrp: 0.0 ± 0.0
1.194ValTyr: 1.194 ± 0.67
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.597TrpAsp: 0.597 ± 0.792
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.194TrpLys: 1.194 ± 0.831
1.791TrpLeu: 1.791 ± 0.738
0.0TrpMet: 0.0 ± 0.0
1.194TrpAsn: 1.194 ± 0.481
0.597TrpPro: 0.597 ± 0.441
1.194TrpGln: 1.194 ± 0.958
0.597TrpArg: 0.597 ± 0.441
1.791TrpSer: 1.791 ± 0.415
0.0TrpThr: 0.0 ± 0.0
0.597TrpVal: 0.597 ± 0.441
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.194TyrAla: 1.194 ± 0.491
0.597TyrCys: 0.597 ± 0.572
2.985TyrAsp: 2.985 ± 1.595
1.194TyrGlu: 1.194 ± 0.787
1.194TyrPhe: 1.194 ± 0.882
4.179TyrGly: 4.179 ± 1.048
1.791TyrHis: 1.791 ± 0.649
1.791TyrIle: 1.791 ± 0.788
1.194TyrLys: 1.194 ± 0.828
2.985TyrLeu: 2.985 ± 1.281
2.985TyrMet: 2.985 ± 1.636
1.791TyrAsn: 1.791 ± 1.15
1.791TyrPro: 1.791 ± 0.913
3.582TyrGln: 3.582 ± 1.298
2.985TyrArg: 2.985 ± 1.145
4.179TyrSer: 4.179 ± 1.433
4.179TyrThr: 4.179 ± 1.93
2.985TyrVal: 2.985 ± 0.803
0.0TyrTrp: 0.0 ± 0.0
2.985TyrTyr: 2.985 ± 0.884
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1676 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski