Amino acid dipepetide frequency for Tomato pseudo-curly top virus (TPCTV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.699AlaAla: 4.699 ± 1.578
0.94AlaCys: 0.94 ± 1.114
3.759AlaAsp: 3.759 ± 2.319
4.699AlaGlu: 4.699 ± 2.785
0.94AlaPhe: 0.94 ± 0.855
0.0AlaGly: 0.0 ± 0.0
0.94AlaHis: 0.94 ± 0.995
1.88AlaIle: 1.88 ± 1.457
3.759AlaLys: 3.759 ± 1.333
8.459AlaLeu: 8.459 ± 2.515
2.82AlaMet: 2.82 ± 1.657
1.88AlaAsn: 1.88 ± 1.007
3.759AlaPro: 3.759 ± 1.519
0.94AlaGln: 0.94 ± 0.668
4.699AlaArg: 4.699 ± 3.341
4.699AlaSer: 4.699 ± 3.505
4.699AlaThr: 4.699 ± 2.343
3.759AlaVal: 3.759 ± 2.319
0.0AlaTrp: 0.0 ± 0.0
0.94AlaTyr: 0.94 ± 0.855
0.0AlaXaa: 0.0 ± 0.0
Cys
1.88CysAla: 1.88 ± 0.792
0.0CysCys: 0.0 ± 0.0
0.94CysAsp: 0.94 ± 0.995
3.759CysGlu: 3.759 ± 2.914
0.0CysPhe: 0.0 ± 0.0
1.88CysGly: 1.88 ± 1.457
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.82CysLys: 2.82 ± 1.19
1.88CysLeu: 1.88 ± 1.602
0.0CysMet: 0.0 ± 0.0
0.94CysAsn: 0.94 ± 0.668
2.82CysPro: 2.82 ± 1.832
1.88CysGln: 1.88 ± 1.489
0.94CysArg: 0.94 ± 1.114
1.88CysSer: 1.88 ± 1.034
1.88CysThr: 1.88 ± 1.71
0.94CysVal: 0.94 ± 0.855
0.94CysTrp: 0.94 ± 1.003
1.88CysTyr: 1.88 ± 1.007
0.0CysXaa: 0.0 ± 0.0
Asp
1.88AspAla: 1.88 ± 0.792
0.94AspCys: 0.94 ± 0.995
4.699AspAsp: 4.699 ± 0.824
1.88AspGlu: 1.88 ± 1.034
3.759AspPhe: 3.759 ± 2.143
3.759AspGly: 3.759 ± 2.067
0.0AspHis: 0.0 ± 0.0
2.82AspIle: 2.82 ± 1.889
4.699AspLys: 4.699 ± 1.209
3.759AspLeu: 3.759 ± 1.519
0.94AspMet: 0.94 ± 0.668
0.94AspAsn: 0.94 ± 0.855
0.0AspPro: 0.0 ± 0.0
2.82AspGln: 2.82 ± 1.006
2.82AspArg: 2.82 ± 1.006
2.82AspSer: 2.82 ± 1.694
1.88AspThr: 1.88 ± 1.336
3.759AspVal: 3.759 ± 1.584
2.82AspTrp: 2.82 ± 1.428
0.94AspTyr: 0.94 ± 0.668
0.0AspXaa: 0.0 ± 0.0
Glu
7.519GluAla: 7.519 ± 2.214
0.94GluCys: 0.94 ± 0.668
2.82GluAsp: 2.82 ± 1.407
4.699GluGlu: 4.699 ± 2.017
0.94GluPhe: 0.94 ± 0.668
1.88GluGly: 1.88 ± 1.336
0.94GluHis: 0.94 ± 0.995
4.699GluIle: 4.699 ± 2.461
0.94GluLys: 0.94 ± 0.668
6.579GluLeu: 6.579 ± 2.064
0.0GluMet: 0.0 ± 0.0
3.759GluAsn: 3.759 ± 1.333
2.82GluPro: 2.82 ± 1.428
0.94GluGln: 0.94 ± 0.995
1.88GluArg: 1.88 ± 1.457
2.82GluSer: 2.82 ± 1.407
2.82GluThr: 2.82 ± 1.542
0.94GluVal: 0.94 ± 1.114
2.82GluTrp: 2.82 ± 1.428
0.94GluTyr: 0.94 ± 0.995
0.0GluXaa: 0.0 ± 0.0
Phe
0.94PheAla: 0.94 ± 1.114
2.82PheCys: 2.82 ± 0.87
3.759PheAsp: 3.759 ± 1.823
0.94PheGlu: 0.94 ± 0.668
0.94PhePhe: 0.94 ± 0.668
0.94PheGly: 0.94 ± 0.668
1.88PheHis: 1.88 ± 1.007
1.88PheIle: 1.88 ± 1.007
0.94PheLys: 0.94 ± 1.003
4.699PheLeu: 4.699 ± 1.808
0.0PheMet: 0.0 ± 0.0
1.88PheAsn: 1.88 ± 1.336
0.94PhePro: 0.94 ± 0.855
4.699PheGln: 4.699 ± 2.382
2.82PheArg: 2.82 ± 1.537
4.699PheSer: 4.699 ± 2.461
2.82PheThr: 2.82 ± 1.428
0.94PheVal: 0.94 ± 0.668
0.0PheTrp: 0.0 ± 0.0
1.88PheTyr: 1.88 ± 2.006
0.0PheXaa: 0.0 ± 0.0
Gly
5.639GlyAla: 5.639 ± 1.287
2.82GlyCys: 2.82 ± 1.268
3.759GlyAsp: 3.759 ± 1.085
7.519GlyGlu: 7.519 ± 1.606
3.759GlyPhe: 3.759 ± 2.217
4.699GlyGly: 4.699 ± 2.402
0.94GlyHis: 0.94 ± 0.668
2.82GlyIle: 2.82 ± 1.916
4.699GlyLys: 4.699 ± 1.808
3.759GlyLeu: 3.759 ± 1.993
0.94GlyMet: 0.94 ± 0.855
5.639GlyAsn: 5.639 ± 2.903
1.88GlyPro: 1.88 ± 0.792
1.88GlyGln: 1.88 ± 1.231
0.0GlyArg: 0.0 ± 0.0
3.759GlySer: 3.759 ± 2.273
2.82GlyThr: 2.82 ± 0.87
2.82GlyVal: 2.82 ± 1.006
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.88HisGlu: 1.88 ± 1.034
1.88HisPhe: 1.88 ± 1.007
0.94HisGly: 0.94 ± 1.114
0.0HisHis: 0.0 ± 0.0
0.94HisIle: 0.94 ± 1.241
0.0HisLys: 0.0 ± 0.0
3.759HisLeu: 3.759 ± 1.313
0.0HisMet: 0.0 ± 0.0
3.759HisAsn: 3.759 ± 1.313
0.94HisPro: 0.94 ± 0.668
0.94HisGln: 0.94 ± 0.995
1.88HisArg: 1.88 ± 1.108
0.94HisSer: 0.94 ± 0.855
0.94HisThr: 0.94 ± 0.995
2.82HisVal: 2.82 ± 1.091
0.94HisTrp: 0.94 ± 0.668
0.94HisTyr: 0.94 ± 0.668
0.0HisXaa: 0.0 ± 0.0
Ile
2.82IleAla: 2.82 ± 1.507
2.82IleCys: 2.82 ± 1.537
3.759IleAsp: 3.759 ± 1.313
3.759IleGlu: 3.759 ± 1.344
0.94IlePhe: 0.94 ± 0.668
0.94IleGly: 0.94 ± 0.668
0.94IleHis: 0.94 ± 0.995
4.699IleIle: 4.699 ± 1.774
9.398IleLys: 9.398 ± 1.572
0.94IleLeu: 0.94 ± 0.855
0.0IleMet: 0.0 ± 0.0
5.639IleAsn: 5.639 ± 2.963
0.94IlePro: 0.94 ± 0.668
2.82IleGln: 2.82 ± 1.607
7.519IleArg: 7.519 ± 2.694
3.759IleSer: 3.759 ± 2.724
3.759IleThr: 3.759 ± 2.929
2.82IleVal: 2.82 ± 1.507
0.94IleTrp: 0.94 ± 0.855
0.94IleTyr: 0.94 ± 1.003
0.0IleXaa: 0.0 ± 0.0
Lys
1.88LysAla: 1.88 ± 1.457
0.94LysCys: 0.94 ± 1.114
2.82LysAsp: 2.82 ± 2.005
5.639LysGlu: 5.639 ± 3.361
2.82LysPhe: 2.82 ± 1.006
6.579LysGly: 6.579 ± 1.921
1.88LysHis: 1.88 ± 1.007
1.88LysIle: 1.88 ± 1.599
4.699LysLys: 4.699 ± 2.637
4.699LysLeu: 4.699 ± 1.578
0.94LysMet: 0.94 ± 1.003
4.699LysAsn: 4.699 ± 1.508
1.88LysPro: 1.88 ± 0.792
0.0LysGln: 0.0 ± 0.0
6.579LysArg: 6.579 ± 3.038
3.759LysSer: 3.759 ± 1.584
4.699LysThr: 4.699 ± 3.154
1.88LysVal: 1.88 ± 1.007
0.94LysTrp: 0.94 ± 0.855
2.82LysTyr: 2.82 ± 1.607
0.0LysXaa: 0.0 ± 0.0
Leu
1.88LeuAla: 1.88 ± 1.108
1.88LeuCys: 1.88 ± 1.034
5.639LeuAsp: 5.639 ± 2.463
0.94LeuGlu: 0.94 ± 1.241
2.82LeuPhe: 2.82 ± 1.416
6.579LeuGly: 6.579 ± 2.04
1.88LeuHis: 1.88 ± 1.336
4.699LeuIle: 4.699 ± 1.296
3.759LeuLys: 3.759 ± 1.76
7.519LeuLeu: 7.519 ± 4.275
0.0LeuMet: 0.0 ± 0.0
5.639LeuAsn: 5.639 ± 2.082
1.88LeuPro: 1.88 ± 1.034
6.579LeuGln: 6.579 ± 3.101
2.82LeuArg: 2.82 ± 1.268
10.338LeuSer: 10.338 ± 1.282
7.519LeuThr: 7.519 ± 2.125
4.699LeuVal: 4.699 ± 1.508
0.0LeuTrp: 0.0 ± 0.0
7.519LeuTyr: 7.519 ± 1.018
0.0LeuXaa: 0.0 ± 0.0
Met
3.759MetAla: 3.759 ± 1.993
0.94MetCys: 0.94 ± 1.241
0.94MetAsp: 0.94 ± 1.003
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.94MetGly: 0.94 ± 1.241
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.88MetLys: 1.88 ± 1.247
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.94MetAsn: 0.94 ± 0.855
1.88MetPro: 1.88 ± 0.792
0.94MetGln: 0.94 ± 0.668
1.88MetArg: 1.88 ± 1.007
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
0.94MetVal: 0.94 ± 0.995
0.94MetTrp: 0.94 ± 0.668
1.88MetTyr: 1.88 ± 1.71
0.0MetXaa: 0.0 ± 0.0
Asn
3.759AsnAla: 3.759 ± 1.574
3.759AsnCys: 3.759 ± 2.143
1.88AsnAsp: 1.88 ± 1.231
2.82AsnGlu: 2.82 ± 2.228
0.0AsnPhe: 0.0 ± 0.0
4.699AsnGly: 4.699 ± 1.592
2.82AsnHis: 2.82 ± 2.096
2.82AsnIle: 2.82 ± 1.091
2.82AsnLys: 2.82 ± 1.006
7.519AsnLeu: 7.519 ± 2.48
0.94AsnMet: 0.94 ± 0.855
5.639AsnAsn: 5.639 ± 4.038
3.759AsnPro: 3.759 ± 1.59
1.88AsnGln: 1.88 ± 1.034
1.88AsnArg: 1.88 ± 1.034
6.579AsnSer: 6.579 ± 3.465
0.94AsnThr: 0.94 ± 1.003
4.699AsnVal: 4.699 ± 1.318
0.0AsnTrp: 0.0 ± 0.0
1.88AsnTyr: 1.88 ± 1.336
0.0AsnXaa: 0.0 ± 0.0
Pro
3.759ProAla: 3.759 ± 1.274
0.0ProCys: 0.0 ± 0.0
3.759ProAsp: 3.759 ± 2.217
2.82ProGlu: 2.82 ± 1.916
1.88ProPhe: 1.88 ± 1.336
3.759ProGly: 3.759 ± 1.258
2.82ProHis: 2.82 ± 2.005
1.88ProIle: 1.88 ± 1.489
3.759ProLys: 3.759 ± 2.067
0.94ProLeu: 0.94 ± 0.668
0.94ProMet: 0.94 ± 1.136
2.82ProAsn: 2.82 ± 1.428
3.759ProPro: 3.759 ± 2.873
3.759ProGln: 3.759 ± 2.007
0.94ProArg: 0.94 ± 1.003
4.699ProSer: 4.699 ± 1.314
5.639ProThr: 5.639 ± 2.704
0.94ProVal: 0.94 ± 0.668
0.0ProTrp: 0.0 ± 0.0
2.82ProTyr: 2.82 ± 2.566
0.0ProXaa: 0.0 ± 0.0
Gln
0.94GlnAla: 0.94 ± 1.114
1.88GlnCys: 1.88 ± 1.247
0.94GlnAsp: 0.94 ± 0.668
1.88GlnGlu: 1.88 ± 1.034
0.94GlnPhe: 0.94 ± 0.668
0.94GlnGly: 0.94 ± 0.668
0.94GlnHis: 0.94 ± 1.241
5.639GlnIle: 5.639 ± 2.767
0.94GlnLys: 0.94 ± 1.114
2.82GlnLeu: 2.82 ± 1.545
0.0GlnMet: 0.0 ± 0.0
1.88GlnAsn: 1.88 ± 1.245
3.759GlnPro: 3.759 ± 2.471
1.88GlnGln: 1.88 ± 0.792
5.639GlnArg: 5.639 ± 1.584
2.82GlnSer: 2.82 ± 0.87
2.82GlnThr: 2.82 ± 1.384
2.82GlnVal: 2.82 ± 2.566
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.94ArgAla: 0.94 ± 1.003
1.88ArgCys: 1.88 ± 1.108
0.94ArgAsp: 0.94 ± 0.668
2.82ArgGlu: 2.82 ± 1.474
5.639ArgPhe: 5.639 ± 1.494
4.699ArgGly: 4.699 ± 1.417
1.88ArgHis: 1.88 ± 1.457
2.82ArgIle: 2.82 ± 1.114
5.639ArgLys: 5.639 ± 2.203
6.579ArgLeu: 6.579 ± 3.09
0.94ArgMet: 0.94 ± 0.925
0.94ArgAsn: 0.94 ± 0.855
2.82ArgPro: 2.82 ± 1.474
0.94ArgGln: 0.94 ± 1.241
3.759ArgArg: 3.759 ± 2.08
8.459ArgSer: 8.459 ± 1.43
4.699ArgThr: 4.699 ± 2.404
1.88ArgVal: 1.88 ± 1.007
0.0ArgTrp: 0.0 ± 0.0
1.88ArgTyr: 1.88 ± 0.792
0.0ArgXaa: 0.0 ± 0.0
Ser
5.639SerAla: 5.639 ± 1.845
2.82SerCys: 2.82 ± 1.399
2.82SerAsp: 2.82 ± 1.114
2.82SerGlu: 2.82 ± 1.399
3.759SerPhe: 3.759 ± 1.638
4.699SerGly: 4.699 ± 2.324
0.0SerHis: 0.0 ± 0.0
10.338SerIle: 10.338 ± 1.672
3.759SerLys: 3.759 ± 1.333
3.759SerLeu: 3.759 ± 1.584
1.88SerMet: 1.88 ± 1.425
4.699SerAsn: 4.699 ± 2.609
4.699SerPro: 4.699 ± 1.084
1.88SerGln: 1.88 ± 1.108
8.459SerArg: 8.459 ± 2.462
10.338SerSer: 10.338 ± 1.923
5.639SerThr: 5.639 ± 4.735
2.82SerVal: 2.82 ± 1.63
0.94SerTrp: 0.94 ± 0.855
3.759SerTyr: 3.759 ± 1.123
0.0SerXaa: 0.0 ± 0.0
Thr
1.88ThrAla: 1.88 ± 1.231
0.94ThrCys: 0.94 ± 0.855
0.94ThrAsp: 0.94 ± 0.855
1.88ThrGlu: 1.88 ± 1.231
0.94ThrPhe: 0.94 ± 0.995
5.639ThrGly: 5.639 ± 2.986
2.82ThrHis: 2.82 ± 1.916
2.82ThrIle: 2.82 ± 0.87
0.0ThrLys: 0.0 ± 0.0
5.639ThrLeu: 5.639 ± 2.32
2.82ThrMet: 2.82 ± 1.006
4.699ThrAsn: 4.699 ± 1.695
5.639ThrPro: 5.639 ± 2.521
0.94ThrGln: 0.94 ± 1.003
2.82ThrArg: 2.82 ± 1.208
6.579ThrSer: 6.579 ± 2.316
5.639ThrThr: 5.639 ± 2.884
2.82ThrVal: 2.82 ± 0.87
1.88ThrTrp: 1.88 ± 1.602
5.639ThrTyr: 5.639 ± 2.401
0.0ThrXaa: 0.0 ± 0.0
Val
2.82ValAla: 2.82 ± 1.507
0.94ValCys: 0.94 ± 1.114
1.88ValAsp: 1.88 ± 0.792
0.94ValGlu: 0.94 ± 0.855
1.88ValPhe: 1.88 ± 1.007
2.82ValGly: 2.82 ± 1.712
0.94ValHis: 0.94 ± 0.995
3.759ValIle: 3.759 ± 1.847
2.82ValLys: 2.82 ± 2.566
5.639ValLeu: 5.639 ± 1.481
1.88ValMet: 1.88 ± 1.008
0.94ValAsn: 0.94 ± 0.668
3.759ValPro: 3.759 ± 1.085
2.82ValGln: 2.82 ± 1.208
0.94ValArg: 0.94 ± 0.855
4.699ValSer: 4.699 ± 2.063
0.94ValThr: 0.94 ± 0.668
2.82ValVal: 2.82 ± 1.889
0.0ValTrp: 0.0 ± 0.0
4.699ValTyr: 4.699 ± 3.154
0.0ValXaa: 0.0 ± 0.0
Trp
3.759TrpAla: 3.759 ± 1.085
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.94TrpGly: 0.94 ± 0.668
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.94TrpLys: 0.94 ± 0.668
1.88TrpLeu: 1.88 ± 1.245
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.94TrpPro: 0.94 ± 0.855
0.94TrpGln: 0.94 ± 0.668
0.94TrpArg: 0.94 ± 0.995
0.94TrpSer: 0.94 ± 0.855
0.94TrpThr: 0.94 ± 0.668
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.94TrpTyr: 0.94 ± 1.241
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.88TyrAla: 1.88 ± 1.247
0.0TyrCys: 0.0 ± 0.0
1.88TyrAsp: 1.88 ± 0.792
0.0TyrGlu: 0.0 ± 0.0
6.579TyrPhe: 6.579 ± 1.556
2.82TyrGly: 2.82 ± 0.87
1.88TyrHis: 1.88 ± 0.792
3.759TyrIle: 3.759 ± 1.574
3.759TyrLys: 3.759 ± 2.319
3.759TyrLeu: 3.759 ± 1.344
1.88TyrMet: 1.88 ± 1.185
3.759TyrAsn: 3.759 ± 1.59
3.759TyrPro: 3.759 ± 1.274
0.0TyrGln: 0.0 ± 0.0
0.94TyrArg: 0.94 ± 1.241
0.94TyrSer: 0.94 ± 0.668
1.88TyrThr: 1.88 ± 1.247
2.82TyrVal: 2.82 ± 1.507
0.0TyrTrp: 0.0 ± 0.0
1.88TyrTyr: 1.88 ± 1.245
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1065 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski