Amino acid dipepetide frequency for Saimiriine herpesvirus 1 (strain MV-5-4-PSL) (SaHV-1) (Marmoset herpesvirus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
22.206AlaAla: 22.206 ± 1.719
2.708AlaCys: 2.708 ± 0.274
7.247AlaAsp: 7.247 ± 0.386
6.654AlaGlu: 6.654 ± 0.565
3.869AlaPhe: 3.869 ± 0.27
9.465AlaGly: 9.465 ± 0.657
2.708AlaHis: 2.708 ± 0.229
3.404AlaIle: 3.404 ± 0.292
2.063AlaLys: 2.063 ± 0.273
13.798AlaLeu: 13.798 ± 0.892
2.089AlaMet: 2.089 ± 0.232
2.347AlaAsn: 2.347 ± 0.251
11.967AlaPro: 11.967 ± 1.341
2.811AlaGln: 2.811 ± 0.263
13.901AlaArg: 13.901 ± 0.747
11.503AlaSer: 11.503 ± 0.591
6.68AlaThr: 6.68 ± 0.492
9.646AlaVal: 9.646 ± 0.671
1.676AlaTrp: 1.676 ± 0.202
3.508AlaTyr: 3.508 ± 0.287
0.0AlaXaa: 0.0 ± 0.0
Cys
2.45CysAla: 2.45 ± 0.264
0.387CysCys: 0.387 ± 0.112
1.238CysAsp: 1.238 ± 0.174
1.006CysGlu: 1.006 ± 0.142
0.696CysPhe: 0.696 ± 0.138
1.418CysGly: 1.418 ± 0.144
0.361CysHis: 0.361 ± 0.108
0.335CysIle: 0.335 ± 0.077
0.232CysLys: 0.232 ± 0.071
2.012CysLeu: 2.012 ± 0.253
0.516CysMet: 0.516 ± 0.107
0.49CysAsn: 0.49 ± 0.117
1.135CysPro: 1.135 ± 0.143
0.258CysGln: 0.258 ± 0.057
1.444CysArg: 1.444 ± 0.187
0.877CysSer: 0.877 ± 0.125
0.722CysThr: 0.722 ± 0.144
1.573CysVal: 1.573 ± 0.218
0.206CysTrp: 0.206 ± 0.076
0.464CysTyr: 0.464 ± 0.098
0.0CysXaa: 0.0 ± 0.0
Asp
8.769AspAla: 8.769 ± 0.557
0.903AspCys: 0.903 ± 0.149
4.745AspAsp: 4.745 ± 0.76
3.972AspGlu: 3.972 ± 0.312
1.599AspPhe: 1.599 ± 0.241
4.745AspGly: 4.745 ± 0.433
1.186AspHis: 1.186 ± 0.219
1.702AspIle: 1.702 ± 0.273
0.309AspLys: 0.309 ± 0.079
4.616AspLeu: 4.616 ± 0.468
0.722AspMet: 0.722 ± 0.122
0.825AspAsn: 0.825 ± 0.166
4.591AspPro: 4.591 ± 0.343
1.057AspGln: 1.057 ± 0.177
4.668AspArg: 4.668 ± 0.328
3.92AspSer: 3.92 ± 0.319
2.141AspThr: 2.141 ± 0.245
4.023AspVal: 4.023 ± 0.303
0.696AspTrp: 0.696 ± 0.145
1.186AspTyr: 1.186 ± 0.124
0.0AspXaa: 0.0 ± 0.0
Glu
7.995GluAla: 7.995 ± 0.456
0.98GluCys: 0.98 ± 0.142
4.023GluAsp: 4.023 ± 0.339
4.101GluGlu: 4.101 ± 0.405
1.702GluPhe: 1.702 ± 0.254
3.714GluGly: 3.714 ± 0.261
1.367GluHis: 1.367 ± 0.174
1.599GluIle: 1.599 ± 0.238
0.851GluLys: 0.851 ± 0.137
5.493GluLeu: 5.493 ± 0.533
0.825GluMet: 0.825 ± 0.139
0.928GluAsn: 0.928 ± 0.122
4.359GluPro: 4.359 ± 0.303
1.238GluGln: 1.238 ± 0.182
4.539GluArg: 4.539 ± 0.298
3.894GluSer: 3.894 ± 0.309
3.869GluThr: 3.869 ± 0.271
2.45GluVal: 2.45 ± 0.209
0.619GluTrp: 0.619 ± 0.094
1.393GluTyr: 1.393 ± 0.196
0.0GluXaa: 0.0 ± 0.0
Phe
3.611PheAla: 3.611 ± 0.274
0.851PheCys: 0.851 ± 0.151
2.012PheAsp: 2.012 ± 0.252
2.192PheGlu: 2.192 ± 0.251
1.496PhePhe: 1.496 ± 0.198
2.631PheGly: 2.631 ± 0.296
0.593PheHis: 0.593 ± 0.119
0.877PheIle: 0.877 ± 0.182
0.696PheLys: 0.696 ± 0.147
3.301PheLeu: 3.301 ± 0.354
0.671PheMet: 0.671 ± 0.152
0.825PheAsn: 0.825 ± 0.148
1.728PhePro: 1.728 ± 0.203
0.748PheGln: 0.748 ± 0.18
2.244PheArg: 2.244 ± 0.242
2.785PheSer: 2.785 ± 0.275
1.367PheThr: 1.367 ± 0.199
3.043PheVal: 3.043 ± 0.311
0.413PheTrp: 0.413 ± 0.094
1.083PheTyr: 1.083 ± 0.165
0.0PheXaa: 0.0 ± 0.0
Gly
9.542GlyAla: 9.542 ± 0.494
1.186GlyCys: 1.186 ± 0.165
5.107GlyAsp: 5.107 ± 0.382
4.642GlyGlu: 4.642 ± 0.372
2.373GlyPhe: 2.373 ± 0.262
7.737GlyGly: 7.737 ± 0.63
1.238GlyHis: 1.238 ± 0.186
1.341GlyIle: 1.341 ± 0.201
1.057GlyLys: 1.057 ± 0.175
6.319GlyLeu: 6.319 ± 0.41
0.851GlyMet: 0.851 ± 0.156
1.057GlyAsn: 1.057 ± 0.179
4.978GlyPro: 4.978 ± 0.465
1.986GlyGln: 1.986 ± 0.217
6.293GlyArg: 6.293 ± 0.523
6.216GlySer: 6.216 ± 0.481
3.585GlyThr: 3.585 ± 0.264
5.364GlyVal: 5.364 ± 0.465
0.954GlyTrp: 0.954 ± 0.159
1.367GlyTyr: 1.367 ± 0.19
0.0GlyXaa: 0.0 ± 0.0
His
3.121HisAla: 3.121 ± 0.29
0.335HisCys: 0.335 ± 0.107
0.748HisAsp: 0.748 ± 0.106
0.748HisGlu: 0.748 ± 0.171
0.593HisPhe: 0.593 ± 0.127
1.393HisGly: 1.393 ± 0.158
0.722HisHis: 0.722 ± 0.147
0.464HisIle: 0.464 ± 0.107
0.671HisLys: 0.671 ± 0.109
2.141HisLeu: 2.141 ± 0.271
0.361HisMet: 0.361 ± 0.086
0.619HisAsn: 0.619 ± 0.142
2.244HisPro: 2.244 ± 0.266
0.954HisGln: 0.954 ± 0.132
2.089HisArg: 2.089 ± 0.2
1.29HisSer: 1.29 ± 0.206
1.161HisThr: 1.161 ± 0.156
1.754HisVal: 1.754 ± 0.192
0.181HisTrp: 0.181 ± 0.063
0.593HisTyr: 0.593 ± 0.109
0.0HisXaa: 0.0 ± 0.0
Ile
3.791IleAla: 3.791 ± 0.409
0.413IleCys: 0.413 ± 0.108
1.47IleAsp: 1.47 ± 0.177
1.367IleGlu: 1.367 ± 0.163
0.877IlePhe: 0.877 ± 0.17
1.651IleGly: 1.651 ± 0.2
0.542IleHis: 0.542 ± 0.136
0.903IleIle: 0.903 ± 0.138
0.671IleLys: 0.671 ± 0.173
1.78IleLeu: 1.78 ± 0.279
0.387IleMet: 0.387 ± 0.112
0.877IleAsn: 0.877 ± 0.174
1.47IlePro: 1.47 ± 0.213
0.774IleGln: 0.774 ± 0.169
1.78IleArg: 1.78 ± 0.256
1.831IleSer: 1.831 ± 0.276
1.831IleThr: 1.831 ± 0.231
1.857IleVal: 1.857 ± 0.188
0.258IleTrp: 0.258 ± 0.064
0.542IleTyr: 0.542 ± 0.111
0.0IleXaa: 0.0 ± 0.0
Lys
1.651LysAla: 1.651 ± 0.224
0.181LysCys: 0.181 ± 0.068
0.645LysAsp: 0.645 ± 0.121
0.464LysGlu: 0.464 ± 0.112
0.49LysPhe: 0.49 ± 0.102
0.774LysGly: 0.774 ± 0.142
0.49LysHis: 0.49 ± 0.124
0.671LysIle: 0.671 ± 0.134
0.8LysLys: 0.8 ± 0.169
1.728LysLeu: 1.728 ± 0.199
0.593LysMet: 0.593 ± 0.1
0.387LysAsn: 0.387 ± 0.093
1.29LysPro: 1.29 ± 0.176
0.671LysGln: 0.671 ± 0.127
2.476LysArg: 2.476 ± 0.236
1.006LysSer: 1.006 ± 0.144
1.238LysThr: 1.238 ± 0.186
0.516LysVal: 0.516 ± 0.095
0.129LysTrp: 0.129 ± 0.046
0.464LysTyr: 0.464 ± 0.117
0.0LysXaa: 0.0 ± 0.0
Leu
13.849LeuAla: 13.849 ± 0.765
1.805LeuCys: 1.805 ± 0.163
4.565LeuAsp: 4.565 ± 0.474
5.468LeuGlu: 5.468 ± 0.257
3.559LeuPhe: 3.559 ± 0.329
6.68LeuGly: 6.68 ± 0.403
1.676LeuHis: 1.676 ± 0.182
2.192LeuIle: 2.192 ± 0.218
1.315LeuLys: 1.315 ± 0.235
9.594LeuLeu: 9.594 ± 0.459
1.728LeuMet: 1.728 ± 0.267
2.166LeuAsn: 2.166 ± 0.291
6.087LeuPro: 6.087 ± 0.433
2.682LeuGln: 2.682 ± 0.281
9.491LeuArg: 9.491 ± 0.507
6.551LeuSer: 6.551 ± 0.417
4.359LeuThr: 4.359 ± 0.301
6.912LeuVal: 6.912 ± 0.389
1.135LeuTrp: 1.135 ± 0.166
2.579LeuTyr: 2.579 ± 0.197
0.0LeuXaa: 0.0 ± 0.0
Met
2.373MetAla: 2.373 ± 0.217
0.309MetCys: 0.309 ± 0.089
0.903MetAsp: 0.903 ± 0.143
0.877MetGlu: 0.877 ± 0.158
0.696MetPhe: 0.696 ± 0.143
0.903MetGly: 0.903 ± 0.124
0.309MetHis: 0.309 ± 0.076
0.413MetIle: 0.413 ± 0.11
0.206MetLys: 0.206 ± 0.063
1.728MetLeu: 1.728 ± 0.22
0.464MetMet: 0.464 ± 0.11
0.309MetAsn: 0.309 ± 0.093
0.619MetPro: 0.619 ± 0.128
0.387MetGln: 0.387 ± 0.096
1.676MetArg: 1.676 ± 0.221
1.341MetSer: 1.341 ± 0.179
0.8MetThr: 0.8 ± 0.146
0.748MetVal: 0.748 ± 0.12
0.309MetTrp: 0.309 ± 0.1
0.49MetTyr: 0.49 ± 0.095
0.0MetXaa: 0.0 ± 0.0
Asn
2.502AsnAla: 2.502 ± 0.317
0.335AsnCys: 0.335 ± 0.093
0.903AsnAsp: 0.903 ± 0.144
0.851AsnGlu: 0.851 ± 0.162
0.954AsnPhe: 0.954 ± 0.137
1.29AsnGly: 1.29 ± 0.207
0.516AsnHis: 0.516 ± 0.143
0.619AsnIle: 0.619 ± 0.107
0.413AsnLys: 0.413 ± 0.128
1.805AsnLeu: 1.805 ± 0.226
0.284AsnMet: 0.284 ± 0.08
0.748AsnAsn: 0.748 ± 0.129
1.315AsnPro: 1.315 ± 0.174
0.825AsnGln: 0.825 ± 0.137
1.264AsnArg: 1.264 ± 0.194
1.418AsnSer: 1.418 ± 0.209
1.212AsnThr: 1.212 ± 0.184
1.418AsnVal: 1.418 ± 0.222
0.181AsnTrp: 0.181 ± 0.061
0.645AsnTyr: 0.645 ± 0.114
0.0AsnXaa: 0.0 ± 0.0
Pro
11.27ProAla: 11.27 ± 1.541
1.186ProCys: 1.186 ± 0.152
4.178ProAsp: 4.178 ± 0.339
4.849ProGlu: 4.849 ± 0.409
1.625ProPhe: 1.625 ± 0.216
6.473ProGly: 6.473 ± 0.436
1.96ProHis: 1.96 ± 0.207
1.754ProIle: 1.754 ± 0.235
1.264ProLys: 1.264 ± 0.17
6.293ProLeu: 6.293 ± 0.459
1.161ProMet: 1.161 ± 0.202
1.032ProAsn: 1.032 ± 0.181
9.671ProPro: 9.671 ± 1.036
1.831ProGln: 1.831 ± 0.194
7.144ProArg: 7.144 ± 0.433
6.319ProSer: 6.319 ± 0.542
4.797ProThr: 4.797 ± 0.462
4.126ProVal: 4.126 ± 0.387
0.593ProTrp: 0.593 ± 0.107
1.393ProTyr: 1.393 ± 0.159
0.0ProXaa: 0.0 ± 0.0
Gln
2.966GlnAla: 2.966 ± 0.295
0.361GlnCys: 0.361 ± 0.079
0.877GlnAsp: 0.877 ± 0.16
1.006GlnGlu: 1.006 ± 0.187
0.748GlnPhe: 0.748 ± 0.152
1.264GlnGly: 1.264 ± 0.199
0.696GlnHis: 0.696 ± 0.108
0.928GlnIle: 0.928 ± 0.129
0.593GlnLys: 0.593 ± 0.125
2.811GlnLeu: 2.811 ± 0.284
0.567GlnMet: 0.567 ± 0.102
0.438GlnAsn: 0.438 ± 0.101
1.805GlnPro: 1.805 ± 0.235
1.083GlnGln: 1.083 ± 0.17
2.914GlnArg: 2.914 ± 0.306
1.908GlnSer: 1.908 ± 0.252
1.702GlnThr: 1.702 ± 0.161
1.805GlnVal: 1.805 ± 0.227
0.361GlnTrp: 0.361 ± 0.11
0.619GlnTyr: 0.619 ± 0.115
0.0GlnXaa: 0.0 ± 0.0
Arg
12.302ArgAla: 12.302 ± 0.77
1.676ArgCys: 1.676 ± 0.19
5.003ArgAsp: 5.003 ± 0.325
5.364ArgGlu: 5.364 ± 0.327
3.275ArgPhe: 3.275 ± 0.297
7.118ArgGly: 7.118 ± 0.441
2.476ArgHis: 2.476 ± 0.222
2.115ArgIle: 2.115 ± 0.253
1.599ArgLys: 1.599 ± 0.255
8.33ArgLeu: 8.33 ± 0.394
1.264ArgMet: 1.264 ± 0.174
1.573ArgAsn: 1.573 ± 0.211
6.68ArgPro: 6.68 ± 0.577
2.708ArgGln: 2.708 ± 0.265
11.967ArgArg: 11.967 ± 1.028
6.499ArgSer: 6.499 ± 0.509
4.023ArgThr: 4.023 ± 0.329
6.164ArgVal: 6.164 ± 0.364
1.006ArgTrp: 1.006 ± 0.155
2.037ArgTyr: 2.037 ± 0.223
0.0ArgXaa: 0.0 ± 0.0
Ser
10.987SerAla: 10.987 ± 0.684
1.238SerCys: 1.238 ± 0.174
4.126SerAsp: 4.126 ± 0.372
4.488SerGlu: 4.488 ± 0.331
2.063SerPhe: 2.063 ± 0.254
6.061SerGly: 6.061 ± 0.417
1.625SerHis: 1.625 ± 0.195
1.496SerIle: 1.496 ± 0.209
1.264SerLys: 1.264 ± 0.195
7.118SerLeu: 7.118 ± 0.526
0.8SerMet: 0.8 ± 0.16
0.954SerAsn: 0.954 ± 0.173
6.577SerPro: 6.577 ± 0.5
1.754SerGln: 1.754 ± 0.27
6.293SerArg: 6.293 ± 0.453
7.376SerSer: 7.376 ± 1.013
3.998SerThr: 3.998 ± 0.356
4.926SerVal: 4.926 ± 0.321
0.851SerTrp: 0.851 ± 0.155
1.109SerTyr: 1.109 ± 0.151
0.0SerXaa: 0.0 ± 0.0
Thr
7.247ThrAla: 7.247 ± 0.422
0.645ThrCys: 0.645 ± 0.136
2.682ThrAsp: 2.682 ± 0.263
3.121ThrGlu: 3.121 ± 0.325
1.728ThrPhe: 1.728 ± 0.245
3.043ThrGly: 3.043 ± 0.356
1.264ThrHis: 1.264 ± 0.156
1.444ThrIle: 1.444 ± 0.174
0.954ThrLys: 0.954 ± 0.132
4.539ThrLeu: 4.539 ± 0.323
0.567ThrMet: 0.567 ± 0.12
1.29ThrAsn: 1.29 ± 0.195
5.416ThrPro: 5.416 ± 0.434
1.651ThrGln: 1.651 ± 0.283
5.055ThrArg: 5.055 ± 0.401
2.889ThrSer: 2.889 ± 0.28
3.198ThrThr: 3.198 ± 0.281
3.301ThrVal: 3.301 ± 0.271
0.464ThrTrp: 0.464 ± 0.084
1.573ThrTyr: 1.573 ± 0.242
0.0ThrXaa: 0.0 ± 0.0
Val
9.207ValAla: 9.207 ± 0.65
1.573ValCys: 1.573 ± 0.163
3.791ValAsp: 3.791 ± 0.362
3.456ValGlu: 3.456 ± 0.308
3.533ValPhe: 3.533 ± 0.314
4.049ValGly: 4.049 ± 0.252
1.444ValHis: 1.444 ± 0.246
1.831ValIle: 1.831 ± 0.259
1.057ValLys: 1.057 ± 0.186
6.989ValLeu: 6.989 ± 0.349
1.264ValMet: 1.264 ± 0.239
1.702ValAsn: 1.702 ± 0.231
4.9ValPro: 4.9 ± 0.318
1.393ValGln: 1.393 ± 0.185
5.132ValArg: 5.132 ± 0.342
5.364ValSer: 5.364 ± 0.377
3.121ValThr: 3.121 ± 0.283
5.906ValVal: 5.906 ± 0.534
0.851ValTrp: 0.851 ± 0.172
2.373ValTyr: 2.373 ± 0.283
0.0ValXaa: 0.0 ± 0.0
Trp
1.315TrpAla: 1.315 ± 0.168
0.206TrpCys: 0.206 ± 0.076
0.464TrpAsp: 0.464 ± 0.092
0.49TrpGlu: 0.49 ± 0.094
0.361TrpPhe: 0.361 ± 0.097
1.083TrpGly: 1.083 ± 0.156
0.335TrpHis: 0.335 ± 0.106
0.284TrpIle: 0.284 ± 0.091
0.206TrpLys: 0.206 ± 0.065
1.212TrpLeu: 1.212 ± 0.172
0.232TrpMet: 0.232 ± 0.081
0.335TrpAsn: 0.335 ± 0.092
0.619TrpPro: 0.619 ± 0.128
0.129TrpGln: 0.129 ± 0.064
1.135TrpArg: 1.135 ± 0.186
0.748TrpSer: 0.748 ± 0.158
0.98TrpThr: 0.98 ± 0.168
0.774TrpVal: 0.774 ± 0.154
0.181TrpTrp: 0.181 ± 0.075
0.206TrpTyr: 0.206 ± 0.062
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.095TyrAla: 3.095 ± 0.266
0.542TyrCys: 0.542 ± 0.097
1.651TyrAsp: 1.651 ± 0.204
0.825TyrGlu: 0.825 ± 0.171
0.928TyrPhe: 0.928 ± 0.155
1.702TyrGly: 1.702 ± 0.184
0.671TyrHis: 0.671 ± 0.126
0.696TyrIle: 0.696 ± 0.122
0.438TyrLys: 0.438 ± 0.137
2.785TyrLeu: 2.785 ± 0.216
0.49TyrMet: 0.49 ± 0.097
0.593TyrAsn: 0.593 ± 0.12
1.47TyrPro: 1.47 ± 0.198
0.516TyrGln: 0.516 ± 0.095
1.702TyrArg: 1.702 ± 0.207
1.367TyrSer: 1.367 ± 0.181
1.29TyrThr: 1.29 ± 0.184
2.631TyrVal: 2.631 ± 0.254
0.232TyrTrp: 0.232 ± 0.072
1.006TyrTyr: 1.006 ± 0.159
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 69 proteins (38775 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski