Amino acid dipepetide frequency for Beihai picorna-like virus 113

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.231AlaAla: 6.231 ± 3.334
2.077AlaCys: 2.077 ± 0.418
3.858AlaAsp: 3.858 ± 0.695
3.858AlaGlu: 3.858 ± 1.026
2.967AlaPhe: 2.967 ± 0.304
2.967AlaGly: 2.967 ± 1.451
1.78AlaHis: 1.78 ± 0.277
3.561AlaIle: 3.561 ± 0.594
4.451AlaLys: 4.451 ± 0.169
5.935AlaLeu: 5.935 ± 1.181
0.593AlaMet: 0.593 ± 0.368
2.374AlaAsn: 2.374 ± 1.134
1.78AlaPro: 1.78 ± 0.871
2.374AlaGln: 2.374 ± 0.56
1.187AlaArg: 1.187 ± 0.58
4.154AlaSer: 4.154 ± 0.311
5.638AlaThr: 5.638 ± 3.044
4.748AlaVal: 4.748 ± 0.546
0.297AlaTrp: 0.297 ± 0.142
3.264AlaTyr: 3.264 ± 0.985
0.0AlaXaa: 0.0 ± 0.0
Cys
1.484CysAla: 1.484 ± 0.708
0.0CysCys: 0.0 ± 0.0
0.297CysAsp: 0.297 ± 0.142
1.187CysGlu: 1.187 ± 0.58
0.593CysPhe: 0.593 ± 0.283
0.593CysGly: 0.593 ± 0.283
0.0CysHis: 0.0 ± 0.0
0.593CysIle: 0.593 ± 0.29
0.593CysLys: 0.593 ± 0.283
1.187CysLeu: 1.187 ± 0.567
0.0CysMet: 0.0 ± 0.0
0.89CysAsn: 0.89 ± 0.425
0.297CysPro: 0.297 ± 0.142
1.187CysGln: 1.187 ± 0.567
0.593CysArg: 0.593 ± 0.29
0.89CysSer: 0.89 ± 0.149
0.89CysThr: 0.89 ± 0.149
0.89CysVal: 0.89 ± 0.149
0.297CysTrp: 0.297 ± 0.142
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.374AspAla: 2.374 ± 0.587
1.187AspCys: 1.187 ± 0.567
2.671AspAsp: 2.671 ± 0.446
3.858AspGlu: 3.858 ± 1.268
2.077AspPhe: 2.077 ± 0.155
2.077AspGly: 2.077 ± 0.418
3.858AspHis: 3.858 ± 0.695
3.264AspIle: 3.264 ± 0.411
3.264AspLys: 3.264 ± 0.411
5.341AspLeu: 5.341 ± 1.403
1.187AspMet: 1.187 ± 0.007
2.671AspAsn: 2.671 ± 1.019
0.89AspPro: 0.89 ± 0.722
1.484AspGln: 1.484 ± 0.135
1.484AspArg: 1.484 ± 0.708
4.154AspSer: 4.154 ± 2.031
3.264AspThr: 3.264 ± 0.736
3.858AspVal: 3.858 ± 1.026
0.593AspTrp: 0.593 ± 0.29
1.484AspTyr: 1.484 ± 0.439
0.0AspXaa: 0.0 ± 0.0
Glu
2.374GluAla: 2.374 ± 0.56
0.593GluCys: 0.593 ± 0.283
4.154GluAsp: 4.154 ± 0.311
4.451GluGlu: 4.451 ± 0.405
3.264GluPhe: 3.264 ± 0.162
3.561GluGly: 3.561 ± 0.594
1.187GluHis: 1.187 ± 0.007
3.561GluIle: 3.561 ± 1.127
9.199GluLys: 9.199 ± 3.245
4.748GluLeu: 4.748 ± 1.174
2.967GluMet: 2.967 ± 0.304
3.858GluAsn: 3.858 ± 1.268
0.89GluPro: 0.89 ± 0.149
2.671GluGln: 2.671 ± 1.019
2.077GluArg: 2.077 ± 0.992
3.858GluSer: 3.858 ± 1.268
2.967GluThr: 2.967 ± 0.843
4.748GluVal: 4.748 ± 1.748
1.484GluTrp: 1.484 ± 0.135
1.484GluTyr: 1.484 ± 0.135
0.0GluXaa: 0.0 ± 0.0
Phe
2.671PheAla: 2.671 ± 1.019
0.89PheCys: 0.89 ± 0.425
2.077PheAsp: 2.077 ± 0.155
2.077PheGlu: 2.077 ± 0.155
2.077PhePhe: 2.077 ± 0.155
1.78PheGly: 1.78 ± 0.277
1.484PheHis: 1.484 ± 0.135
2.374PheIle: 2.374 ± 1.134
2.967PheLys: 2.967 ± 1.417
5.045PheLeu: 5.045 ± 1.835
0.89PheMet: 0.89 ± 0.425
1.484PheAsn: 1.484 ± 0.439
1.484PhePro: 1.484 ± 0.135
1.484PheGln: 1.484 ± 0.439
2.374PheArg: 2.374 ± 1.161
4.451PheSer: 4.451 ± 1.89
2.967PheThr: 2.967 ± 0.877
3.858PheVal: 3.858 ± 1.268
0.0PheTrp: 0.0 ± 0.0
0.593PheTyr: 0.593 ± 0.29
0.0PheXaa: 0.0 ± 0.0
Gly
3.561GlyAla: 3.561 ± 2.315
0.297GlyCys: 0.297 ± 0.142
3.561GlyAsp: 3.561 ± 0.02
4.748GlyGlu: 4.748 ± 1.748
1.187GlyPhe: 1.187 ± 0.007
2.374GlyGly: 2.374 ± 1.161
1.187GlyHis: 1.187 ± 0.58
2.967GlyIle: 2.967 ± 0.27
5.935GlyLys: 5.935 ± 2.26
4.154GlyLeu: 4.154 ± 2.031
2.077GlyMet: 2.077 ± 0.155
1.484GlyAsn: 1.484 ± 0.135
1.78GlyPro: 1.78 ± 0.297
1.78GlyGln: 1.78 ± 0.871
1.484GlyArg: 1.484 ± 0.439
3.561GlySer: 3.561 ± 0.02
3.264GlyThr: 3.264 ± 0.985
3.858GlyVal: 3.858 ± 1.6
0.297GlyTrp: 0.297 ± 0.142
3.561GlyTyr: 3.561 ± 0.02
0.0GlyXaa: 0.0 ± 0.0
His
1.484HisAla: 1.484 ± 0.135
0.593HisCys: 0.593 ± 0.864
0.593HisAsp: 0.593 ± 0.283
0.89HisGlu: 0.89 ± 0.425
0.89HisPhe: 0.89 ± 0.149
1.78HisGly: 1.78 ± 0.85
1.484HisHis: 1.484 ± 1.012
2.374HisIle: 2.374 ± 0.014
2.077HisLys: 2.077 ± 0.155
2.967HisLeu: 2.967 ± 0.27
0.297HisMet: 0.297 ± 0.432
0.89HisAsn: 0.89 ± 0.425
1.187HisPro: 1.187 ± 0.007
0.89HisGln: 0.89 ± 0.149
1.78HisArg: 1.78 ± 0.85
2.374HisSer: 2.374 ± 0.56
1.187HisThr: 1.187 ± 0.567
2.671HisVal: 2.671 ± 1.019
0.593HisTrp: 0.593 ± 0.29
1.78HisTyr: 1.78 ± 0.277
0.0HisXaa: 0.0 ± 0.0
Ile
4.451IleAla: 4.451 ± 2.125
0.89IleCys: 0.89 ± 0.722
3.264IleAsp: 3.264 ± 1.883
3.561IleGlu: 3.561 ± 0.553
2.077IlePhe: 2.077 ± 0.992
2.671IleGly: 2.671 ± 0.702
2.077IleHis: 2.077 ± 0.155
2.967IleIle: 2.967 ± 0.843
3.264IleLys: 3.264 ± 0.736
6.231IleLeu: 6.231 ± 0.681
1.187IleMet: 1.187 ± 0.007
1.484IleAsn: 1.484 ± 0.708
5.341IlePro: 5.341 ± 0.317
2.374IleGln: 2.374 ± 0.014
0.593IleArg: 0.593 ± 0.283
5.638IleSer: 5.638 ± 0.971
3.858IleThr: 3.858 ± 0.452
2.671IleVal: 2.671 ± 0.446
0.297IleTrp: 0.297 ± 0.142
2.077IleTyr: 2.077 ± 0.155
0.0IleXaa: 0.0 ± 0.0
Lys
3.561LysAla: 3.561 ± 0.02
0.89LysCys: 0.89 ± 0.149
5.045LysAsp: 5.045 ± 1.262
6.528LysGlu: 6.528 ± 1.97
3.561LysPhe: 3.561 ± 0.553
4.748LysGly: 4.748 ± 0.027
1.484LysHis: 1.484 ± 0.135
5.045LysIle: 5.045 ± 0.114
4.748LysLys: 4.748 ± 2.267
6.231LysLeu: 6.231 ± 1.255
2.671LysMet: 2.671 ± 0.809
5.045LysAsn: 5.045 ± 1.262
2.374LysPro: 2.374 ± 1.161
3.264LysGln: 3.264 ± 0.985
3.264LysArg: 3.264 ± 0.985
3.561LysSer: 3.561 ± 0.553
6.825LysThr: 6.825 ± 0.183
6.231LysVal: 6.231 ± 1.255
0.593LysTrp: 0.593 ± 0.29
2.374LysTyr: 2.374 ± 0.587
0.0LysXaa: 0.0 ± 0.0
Leu
5.935LeuAla: 5.935 ± 3.476
1.187LeuCys: 1.187 ± 0.567
3.264LeuAsp: 3.264 ± 0.736
6.528LeuGlu: 6.528 ± 0.324
2.077LeuPhe: 2.077 ± 0.418
3.858LeuGly: 3.858 ± 1.6
2.671LeuHis: 2.671 ± 0.128
4.154LeuIle: 4.154 ± 0.884
7.418LeuLys: 7.418 ± 1.248
6.825LeuLeu: 6.825 ± 2.112
1.187LeuMet: 1.187 ± 0.567
4.748LeuAsn: 4.748 ± 0.601
5.638LeuPro: 5.638 ± 0.971
4.451LeuGln: 4.451 ± 0.743
3.858LeuArg: 3.858 ± 1.268
8.012LeuSer: 8.012 ± 0.189
7.122LeuThr: 7.122 ± 1.188
5.638LeuVal: 5.638 ± 0.176
0.297LeuTrp: 0.297 ± 0.142
2.967LeuTyr: 2.967 ± 0.843
0.0LeuXaa: 0.0 ± 0.0
Met
1.187MetAla: 1.187 ± 0.007
0.297MetCys: 0.297 ± 0.142
0.297MetAsp: 0.297 ± 0.432
1.484MetGlu: 1.484 ± 0.708
0.593MetPhe: 0.593 ± 0.283
0.297MetGly: 0.297 ± 0.142
0.593MetHis: 0.593 ± 0.283
2.077MetIle: 2.077 ± 0.418
2.077MetLys: 2.077 ± 0.992
3.858MetLeu: 3.858 ± 1.6
1.187MetMet: 1.187 ± 0.007
1.484MetAsn: 1.484 ± 0.439
0.593MetPro: 0.593 ± 0.283
1.78MetGln: 1.78 ± 0.297
0.89MetArg: 0.89 ± 0.425
2.671MetSer: 2.671 ± 0.128
2.077MetThr: 2.077 ± 1.303
1.187MetVal: 1.187 ± 0.567
0.593MetTrp: 0.593 ± 0.29
0.89MetTyr: 0.89 ± 0.425
0.0MetXaa: 0.0 ± 0.0
Asn
2.967AsnAla: 2.967 ± 0.27
0.297AsnCys: 0.297 ± 0.142
2.374AsnAsp: 2.374 ± 0.014
1.484AsnGlu: 1.484 ± 0.439
1.78AsnPhe: 1.78 ± 0.871
2.077AsnGly: 2.077 ± 0.418
0.593AsnHis: 0.593 ± 0.29
2.374AsnIle: 2.374 ± 1.134
2.967AsnLys: 2.967 ± 0.304
4.451AsnLeu: 4.451 ± 0.978
2.077AsnMet: 2.077 ± 0.155
1.484AsnAsn: 1.484 ± 0.708
4.154AsnPro: 4.154 ± 0.884
2.077AsnGln: 2.077 ± 0.992
2.671AsnArg: 2.671 ± 1.275
4.451AsnSer: 4.451 ± 0.978
2.967AsnThr: 2.967 ± 0.27
1.484AsnVal: 1.484 ± 0.708
0.593AsnTrp: 0.593 ± 0.29
2.077AsnTyr: 2.077 ± 0.155
0.0AsnXaa: 0.0 ± 0.0
Pro
3.264ProAla: 3.264 ± 1.309
0.593ProCys: 0.593 ± 0.283
2.077ProAsp: 2.077 ± 0.418
3.858ProGlu: 3.858 ± 0.452
1.78ProPhe: 1.78 ± 0.297
2.967ProGly: 2.967 ± 0.877
0.89ProHis: 0.89 ± 0.425
2.374ProIle: 2.374 ± 0.587
2.077ProLys: 2.077 ± 1.303
4.748ProLeu: 4.748 ± 0.546
1.187ProMet: 1.187 ± 0.58
0.89ProAsn: 0.89 ± 0.149
2.077ProPro: 2.077 ± 0.155
2.077ProGln: 2.077 ± 0.729
1.484ProArg: 1.484 ± 0.708
5.045ProSer: 5.045 ± 1.606
1.187ProThr: 1.187 ± 1.154
2.671ProVal: 2.671 ± 0.702
1.187ProTrp: 1.187 ± 0.567
0.593ProTyr: 0.593 ± 0.29
0.0ProXaa: 0.0 ± 0.0
Gln
3.264GlnAla: 3.264 ± 0.736
0.0GlnCys: 0.0 ± 0.0
2.374GlnAsp: 2.374 ± 0.014
1.187GlnGlu: 1.187 ± 0.567
2.077GlnPhe: 2.077 ± 0.992
2.967GlnGly: 2.967 ± 0.304
1.187GlnHis: 1.187 ± 0.567
2.374GlnIle: 2.374 ± 0.56
5.045GlnLys: 5.045 ± 0.114
2.671GlnLeu: 2.671 ± 0.446
0.593GlnMet: 0.593 ± 0.29
2.077GlnAsn: 2.077 ± 0.992
1.484GlnPro: 1.484 ± 1.012
1.78GlnGln: 1.78 ± 0.871
2.967GlnArg: 2.967 ± 0.304
3.561GlnSer: 3.561 ± 0.594
2.967GlnThr: 2.967 ± 0.27
2.967GlnVal: 2.967 ± 0.304
0.593GlnTrp: 0.593 ± 0.283
0.89GlnTyr: 0.89 ± 0.425
0.0GlnXaa: 0.0 ± 0.0
Arg
1.187ArgAla: 1.187 ± 0.007
0.593ArgCys: 0.593 ± 0.283
2.077ArgAsp: 2.077 ± 0.418
1.187ArgGlu: 1.187 ± 0.567
2.077ArgPhe: 2.077 ± 0.155
1.187ArgGly: 1.187 ± 0.58
0.593ArgHis: 0.593 ± 0.29
2.077ArgIle: 2.077 ± 0.992
3.858ArgLys: 3.858 ± 1.268
4.154ArgLeu: 4.154 ± 1.458
1.78ArgMet: 1.78 ± 0.85
1.187ArgAsn: 1.187 ± 0.567
0.89ArgPro: 0.89 ± 0.149
3.858ArgGln: 3.858 ± 1.842
1.484ArgArg: 1.484 ± 0.135
3.561ArgSer: 3.561 ± 1.127
3.858ArgThr: 3.858 ± 0.695
2.374ArgVal: 2.374 ± 0.587
0.593ArgTrp: 0.593 ± 0.283
1.78ArgTyr: 1.78 ± 0.277
0.0ArgXaa: 0.0 ± 0.0
Ser
5.341SerAla: 5.341 ± 1.403
0.89SerCys: 0.89 ± 0.425
3.858SerAsp: 3.858 ± 0.695
5.045SerGlu: 5.045 ± 1.262
4.748SerPhe: 4.748 ± 0.601
6.528SerGly: 6.528 ± 1.471
2.077SerHis: 2.077 ± 0.418
3.264SerIle: 3.264 ± 0.411
5.341SerLys: 5.341 ± 2.038
4.748SerLeu: 4.748 ± 1.174
1.78SerMet: 1.78 ± 0.277
3.858SerAsn: 3.858 ± 1.268
2.967SerPro: 2.967 ± 0.304
3.858SerGln: 3.858 ± 1.026
2.671SerArg: 2.671 ± 0.702
6.825SerSer: 6.825 ± 3.051
5.638SerThr: 5.638 ± 1.897
5.638SerVal: 5.638 ± 0.176
1.78SerTrp: 1.78 ± 0.277
2.077SerTyr: 2.077 ± 0.418
0.0SerXaa: 0.0 ± 0.0
Thr
5.638ThrAla: 5.638 ± 0.176
0.297ThrCys: 0.297 ± 0.142
2.671ThrAsp: 2.671 ± 1.019
3.858ThrGlu: 3.858 ± 0.695
1.484ThrPhe: 1.484 ± 0.135
3.561ThrGly: 3.561 ± 0.594
1.484ThrHis: 1.484 ± 0.708
4.451ThrIle: 4.451 ± 0.743
4.748ThrLys: 4.748 ± 1.174
7.715ThrLeu: 7.715 ± 2.052
1.484ThrMet: 1.484 ± 0.708
4.451ThrAsn: 4.451 ± 1.89
3.858ThrPro: 3.858 ± 1.6
1.78ThrGln: 1.78 ± 0.277
3.264ThrArg: 3.264 ± 1.559
4.748ThrSer: 4.748 ± 1.12
5.638ThrThr: 5.638 ± 0.971
3.264ThrVal: 3.264 ± 0.985
1.187ThrTrp: 1.187 ± 0.58
3.561ThrTyr: 3.561 ± 1.168
0.0ThrXaa: 0.0 ± 0.0
Val
5.638ValAla: 5.638 ± 0.176
0.593ValCys: 0.593 ± 0.29
3.858ValAsp: 3.858 ± 1.6
4.451ValGlu: 4.451 ± 0.978
4.451ValPhe: 4.451 ± 0.405
5.638ValGly: 5.638 ± 1.897
1.187ValHis: 1.187 ± 0.007
5.045ValIle: 5.045 ± 1.033
5.045ValLys: 5.045 ± 0.688
2.374ValLeu: 2.374 ± 0.587
1.187ValMet: 1.187 ± 0.007
2.967ValAsn: 2.967 ± 0.843
3.561ValPro: 3.561 ± 0.02
2.374ValGln: 2.374 ± 0.56
3.561ValArg: 3.561 ± 1.168
4.154ValSer: 4.154 ± 0.311
3.858ValThr: 3.858 ± 1.268
4.748ValVal: 4.748 ± 0.546
0.297ValTrp: 0.297 ± 0.142
2.077ValTyr: 2.077 ± 0.418
0.0ValXaa: 0.0 ± 0.0
Trp
0.89TrpAla: 0.89 ± 0.425
0.0TrpCys: 0.0 ± 0.0
0.593TrpAsp: 0.593 ± 0.283
0.593TrpGlu: 0.593 ± 0.29
2.077TrpPhe: 2.077 ± 0.729
0.89TrpGly: 0.89 ± 0.149
0.89TrpHis: 0.89 ± 0.149
0.593TrpIle: 0.593 ± 0.29
0.593TrpLys: 0.593 ± 0.283
0.593TrpLeu: 0.593 ± 0.283
0.593TrpMet: 0.593 ± 0.283
0.593TrpAsn: 0.593 ± 0.283
0.0TrpPro: 0.0 ± 0.0
0.297TrpGln: 0.297 ± 0.142
0.297TrpArg: 0.297 ± 0.142
0.593TrpSer: 0.593 ± 0.283
0.89TrpThr: 0.89 ± 0.425
1.187TrpVal: 1.187 ± 0.58
0.593TrpTrp: 0.593 ± 0.283
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.89TyrAla: 0.89 ± 0.149
0.297TyrCys: 0.297 ± 0.142
2.077TyrAsp: 2.077 ± 0.992
3.264TyrGlu: 3.264 ± 0.411
1.187TyrPhe: 1.187 ± 0.007
0.593TyrGly: 0.593 ± 0.283
2.077TyrHis: 2.077 ± 0.729
1.484TyrIle: 1.484 ± 0.135
2.374TyrLys: 2.374 ± 0.56
3.858TyrLeu: 3.858 ± 0.121
0.89TyrMet: 0.89 ± 0.149
1.484TyrAsn: 1.484 ± 1.012
1.78TyrPro: 1.78 ± 0.277
1.187TyrGln: 1.187 ± 0.007
2.374TyrArg: 2.374 ± 0.014
2.671TyrSer: 2.671 ± 1.019
2.077TyrThr: 2.077 ± 0.992
2.374TyrVal: 2.374 ± 0.014
0.593TyrTrp: 0.593 ± 0.283
1.187TyrTyr: 1.187 ± 0.007
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3371 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski