Amino acid dipepetide frequency for Atopobium rimae ATCC 49626

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.495AlaAla: 10.495 ± 0.204
1.544AlaCys: 1.544 ± 0.068
5.971AlaAsp: 5.971 ± 0.132
6.239AlaGlu: 6.239 ± 0.114
3.673AlaPhe: 3.673 ± 0.098
7.397AlaGly: 7.397 ± 0.13
2.576AlaHis: 2.576 ± 0.084
5.903AlaIle: 5.903 ± 0.131
4.658AlaLys: 4.658 ± 0.106
10.495AlaLeu: 10.495 ± 0.185
2.488AlaMet: 2.488 ± 0.069
2.865AlaAsn: 2.865 ± 0.084
3.261AlaPro: 3.261 ± 0.098
3.836AlaGln: 3.836 ± 0.092
5.287AlaArg: 5.287 ± 0.127
5.903AlaSer: 5.903 ± 0.12
5.338AlaThr: 5.338 ± 0.126
6.909AlaVal: 6.909 ± 0.145
0.975AlaTrp: 0.975 ± 0.056
2.896AlaTyr: 2.896 ± 0.084
0.0AlaXaa: 0.0 ± 0.0
Cys
1.412CysAla: 1.412 ± 0.059
0.245CysCys: 0.245 ± 0.026
0.886CysAsp: 0.886 ± 0.049
0.882CysGlu: 0.882 ± 0.049
0.441CysPhe: 0.441 ± 0.032
1.437CysGly: 1.437 ± 0.054
0.326CysHis: 0.326 ± 0.027
0.928CysIle: 0.928 ± 0.042
0.491CysLys: 0.491 ± 0.028
1.016CysLeu: 1.016 ± 0.043
0.361CysMet: 0.361 ± 0.027
0.468CysAsn: 0.468 ± 0.029
0.68CysPro: 0.68 ± 0.045
0.33CysGln: 0.33 ± 0.024
0.639CysArg: 0.639 ± 0.039
0.847CysSer: 0.847 ± 0.041
0.771CysThr: 0.771 ± 0.036
1.14CysVal: 1.14 ± 0.05
0.138CysTrp: 0.138 ± 0.017
0.357CysTyr: 0.357 ± 0.029
0.0CysXaa: 0.0 ± 0.0
Asp
6.585AspAla: 6.585 ± 0.131
0.705AspCys: 0.705 ± 0.042
3.504AspAsp: 3.504 ± 0.103
4.782AspGlu: 4.782 ± 0.107
2.562AspPhe: 2.562 ± 0.083
4.706AspGly: 4.706 ± 0.119
1.175AspHis: 1.175 ± 0.051
3.879AspIle: 3.879 ± 0.087
2.655AspLys: 2.655 ± 0.083
5.279AspLeu: 5.279 ± 0.114
1.577AspMet: 1.577 ± 0.05
1.865AspAsn: 1.865 ± 0.058
2.515AspPro: 2.515 ± 0.077
1.581AspGln: 1.581 ± 0.065
2.649AspArg: 2.649 ± 0.083
3.298AspSer: 3.298 ± 0.076
3.718AspThr: 3.718 ± 0.092
4.92AspVal: 4.92 ± 0.096
0.703AspTrp: 0.703 ± 0.046
1.795AspTyr: 1.795 ± 0.078
0.0AspXaa: 0.0 ± 0.0
Glu
6.635GluAla: 6.635 ± 0.133
0.703GluCys: 0.703 ± 0.041
3.551GluAsp: 3.551 ± 0.107
4.44GluGlu: 4.44 ± 0.124
2.113GluPhe: 2.113 ± 0.069
4.314GluGly: 4.314 ± 0.093
1.569GluHis: 1.569 ± 0.061
3.935GluIle: 3.935 ± 0.096
4.545GluLys: 4.545 ± 0.094
6.686GluLeu: 6.686 ± 0.136
1.684GluMet: 1.684 ± 0.057
2.461GluAsn: 2.461 ± 0.077
2.121GluPro: 2.121 ± 0.077
2.508GluGln: 2.508 ± 0.083
3.982GluArg: 3.982 ± 0.105
3.29GluSer: 3.29 ± 0.09
3.219GluThr: 3.219 ± 0.067
4.821GluVal: 4.821 ± 0.098
0.598GluTrp: 0.598 ± 0.036
1.793GluTyr: 1.793 ± 0.057
0.0GluXaa: 0.0 ± 0.0
Phe
3.529PheAla: 3.529 ± 0.086
0.719PheCys: 0.719 ± 0.037
2.879PheAsp: 2.879 ± 0.069
2.498PheGlu: 2.498 ± 0.077
1.589PhePhe: 1.589 ± 0.078
3.432PheGly: 3.432 ± 0.096
0.666PheHis: 0.666 ± 0.039
2.218PheIle: 2.218 ± 0.067
1.583PheLys: 1.583 ± 0.049
3.366PheLeu: 3.366 ± 0.09
0.993PheMet: 0.993 ± 0.048
1.257PheAsn: 1.257 ± 0.049
1.303PhePro: 1.303 ± 0.054
0.915PheGln: 0.915 ± 0.047
1.538PheArg: 1.538 ± 0.059
3.1PheSer: 3.1 ± 0.091
2.267PheThr: 2.267 ± 0.076
3.244PheVal: 3.244 ± 0.094
0.443PheTrp: 0.443 ± 0.029
1.109PheTyr: 1.109 ± 0.052
0.0PheXaa: 0.0 ± 0.0
Gly
6.802GlyAla: 6.802 ± 0.116
1.107GlyCys: 1.107 ± 0.053
3.908GlyAsp: 3.908 ± 0.101
4.596GlyGlu: 4.596 ± 0.116
3.24GlyPhe: 3.24 ± 0.092
5.47GlyGly: 5.47 ± 0.133
1.686GlyHis: 1.686 ± 0.066
5.563GlyIle: 5.563 ± 0.114
4.19GlyLys: 4.19 ± 0.106
6.422GlyLeu: 6.422 ± 0.124
2.104GlyMet: 2.104 ± 0.064
2.605GlyAsn: 2.605 ± 0.066
1.861GlyPro: 1.861 ± 0.068
2.156GlyGln: 2.156 ± 0.063
3.766GlyArg: 3.766 ± 0.104
4.936GlySer: 4.936 ± 0.096
4.811GlyThr: 4.811 ± 0.119
5.882GlyVal: 5.882 ± 0.107
0.868GlyTrp: 0.868 ± 0.044
2.537GlyTyr: 2.537 ± 0.071
0.0GlyXaa: 0.0 ± 0.0
His
2.119HisAla: 2.119 ± 0.068
0.293HisCys: 0.293 ± 0.024
1.459HisAsp: 1.459 ± 0.053
1.498HisGlu: 1.498 ± 0.053
0.824HisPhe: 0.824 ± 0.041
1.808HisGly: 1.808 ± 0.064
0.546HisHis: 0.546 ± 0.042
1.465HisIle: 1.465 ± 0.057
0.919HisLys: 0.919 ± 0.048
1.841HisLeu: 1.841 ± 0.067
0.596HisMet: 0.596 ± 0.034
0.748HisAsn: 0.748 ± 0.043
1.218HisPro: 1.218 ± 0.047
0.569HisGln: 0.569 ± 0.037
1.084HisArg: 1.084 ± 0.052
0.987HisSer: 0.987 ± 0.046
1.43HisThr: 1.43 ± 0.049
1.828HisVal: 1.828 ± 0.067
0.225HisTrp: 0.225 ± 0.023
0.674HisTyr: 0.674 ± 0.035
0.0HisXaa: 0.0 ± 0.0
Ile
6.476IleAla: 6.476 ± 0.13
1.01IleCys: 1.01 ± 0.048
4.149IleAsp: 4.149 ± 0.094
3.924IleGlu: 3.924 ± 0.096
2.164IlePhe: 2.164 ± 0.074
4.483IleGly: 4.483 ± 0.1
1.158IleHis: 1.158 ± 0.051
3.479IleIle: 3.479 ± 0.107
2.595IleLys: 2.595 ± 0.088
5.192IleLeu: 5.192 ± 0.114
1.346IleMet: 1.346 ± 0.056
2.005IleAsn: 2.005 ± 0.068
2.9IlePro: 2.9 ± 0.07
1.68IleGln: 1.68 ± 0.056
3.125IleArg: 3.125 ± 0.073
4.293IleSer: 4.293 ± 0.098
3.683IleThr: 3.683 ± 0.095
4.887IleVal: 4.887 ± 0.119
0.505IleTrp: 0.505 ± 0.032
1.667IleTyr: 1.667 ± 0.062
0.0IleXaa: 0.0 ± 0.0
Lys
4.592LysAla: 4.592 ± 0.117
0.383LysCys: 0.383 ± 0.032
3.11LysAsp: 3.11 ± 0.092
3.288LysGlu: 3.288 ± 0.093
1.354LysPhe: 1.354 ± 0.051
3.219LysGly: 3.219 ± 0.08
1.066LysHis: 1.066 ± 0.048
2.9LysIle: 2.9 ± 0.066
3.331LysLys: 3.331 ± 0.1
4.18LysLeu: 4.18 ± 0.086
1.214LysMet: 1.214 ± 0.051
2.253LysAsn: 2.253 ± 0.067
2.055LysPro: 2.055 ± 0.067
1.832LysGln: 1.832 ± 0.069
3.017LysArg: 3.017 ± 0.086
2.937LysSer: 2.937 ± 0.092
3.323LysThr: 3.323 ± 0.084
3.327LysVal: 3.327 ± 0.096
0.488LysTrp: 0.488 ± 0.031
1.331LysTyr: 1.331 ± 0.058
0.0LysXaa: 0.0 ± 0.0
Leu
9.726LeuAla: 9.726 ± 0.158
1.331LeuCys: 1.331 ± 0.053
5.771LeuAsp: 5.771 ± 0.123
5.594LeuGlu: 5.594 ± 0.117
3.78LeuPhe: 3.78 ± 0.095
6.969LeuGly: 6.969 ± 0.126
1.987LeuHis: 1.987 ± 0.067
5.225LeuIle: 5.225 ± 0.129
4.252LeuLys: 4.252 ± 0.089
8.756LeuLeu: 8.756 ± 0.18
2.469LeuMet: 2.469 ± 0.069
2.836LeuAsn: 2.836 ± 0.08
4.03LeuPro: 4.03 ± 0.104
2.609LeuGln: 2.609 ± 0.08
4.852LeuArg: 4.852 ± 0.119
7.259LeuSer: 7.259 ± 0.141
5.47LeuThr: 5.47 ± 0.111
7.076LeuVal: 7.076 ± 0.139
0.847LeuTrp: 0.847 ± 0.045
2.383LeuTyr: 2.383 ± 0.074
0.0LeuXaa: 0.0 ± 0.0
Met
2.671MetAla: 2.671 ± 0.069
0.317MetCys: 0.317 ± 0.026
1.435MetAsp: 1.435 ± 0.05
1.296MetGlu: 1.296 ± 0.048
0.802MetPhe: 0.802 ± 0.039
2.09MetGly: 2.09 ± 0.069
0.515MetHis: 0.515 ± 0.032
1.245MetIle: 1.245 ± 0.048
1.146MetLys: 1.146 ± 0.043
2.319MetLeu: 2.319 ± 0.063
0.604MetMet: 0.604 ± 0.039
1.035MetAsn: 1.035 ± 0.052
1.325MetPro: 1.325 ± 0.051
0.892MetGln: 0.892 ± 0.037
1.614MetArg: 1.614 ± 0.058
1.845MetSer: 1.845 ± 0.062
1.513MetThr: 1.513 ± 0.047
1.723MetVal: 1.723 ± 0.06
0.237MetTrp: 0.237 ± 0.021
0.668MetTyr: 0.668 ± 0.034
0.0MetXaa: 0.0 ± 0.0
Asn
3.174AsnAla: 3.174 ± 0.088
0.363AsnCys: 0.363 ± 0.028
1.931AsnAsp: 1.931 ± 0.066
2.076AsnGlu: 2.076 ± 0.07
1.208AsnPhe: 1.208 ± 0.043
2.568AsnGly: 2.568 ± 0.083
0.666AsnHis: 0.666 ± 0.038
2.142AsnIle: 2.142 ± 0.078
1.538AsnLys: 1.538 ± 0.058
3.285AsnLeu: 3.285 ± 0.084
0.75AsnMet: 0.75 ± 0.039
1.286AsnAsn: 1.286 ± 0.055
1.997AsnPro: 1.997 ± 0.06
1.049AsnGln: 1.049 ± 0.052
1.667AsnArg: 1.667 ± 0.059
1.933AsnSer: 1.933 ± 0.072
2.08AsnThr: 2.08 ± 0.064
2.708AsnVal: 2.708 ± 0.075
0.385AsnTrp: 0.385 ± 0.031
1.074AsnTyr: 1.074 ± 0.047
0.0AsnXaa: 0.0 ± 0.0
Pro
3.626ProAla: 3.626 ± 0.103
0.435ProCys: 0.435 ± 0.033
2.449ProAsp: 2.449 ± 0.075
3.335ProGlu: 3.335 ± 0.079
1.674ProPhe: 1.674 ± 0.056
2.63ProGly: 2.63 ± 0.079
1.055ProHis: 1.055 ± 0.046
2.21ProIle: 2.21 ± 0.073
2.014ProLys: 2.014 ± 0.073
3.525ProLeu: 3.525 ± 0.086
0.775ProMet: 0.775 ± 0.037
1.331ProAsn: 1.331 ± 0.053
0.921ProPro: 0.921 ± 0.044
1.536ProGln: 1.536 ± 0.058
1.719ProArg: 1.719 ± 0.059
2.75ProSer: 2.75 ± 0.078
2.449ProThr: 2.449 ± 0.088
3.184ProVal: 3.184 ± 0.065
0.453ProTrp: 0.453 ± 0.032
1.344ProTyr: 1.344 ± 0.055
0.0ProXaa: 0.0 ± 0.0
Gln
3.228GlnAla: 3.228 ± 0.083
0.295GlnCys: 0.295 ± 0.027
1.789GlnAsp: 1.789 ± 0.057
2.337GlnGlu: 2.337 ± 0.068
0.967GlnPhe: 0.967 ± 0.047
2.269GlnGly: 2.269 ± 0.06
0.602GlnHis: 0.602 ± 0.033
1.958GlnIle: 1.958 ± 0.064
2.121GlnLys: 2.121 ± 0.08
2.985GlnLeu: 2.985 ± 0.081
0.967GlnMet: 0.967 ± 0.04
1.237GlnAsn: 1.237 ± 0.055
1.222GlnPro: 1.222 ± 0.061
1.292GlnGln: 1.292 ± 0.054
1.904GlnArg: 1.904 ± 0.074
1.911GlnSer: 1.911 ± 0.066
2.028GlnThr: 2.028 ± 0.065
2.251GlnVal: 2.251 ± 0.07
0.276GlnTrp: 0.276 ± 0.023
0.88GlnTyr: 0.88 ± 0.044
0.0GlnXaa: 0.0 ± 0.0
Arg
5.039ArgAla: 5.039 ± 0.11
0.594ArgCys: 0.594 ± 0.039
2.739ArgAsp: 2.739 ± 0.075
3.879ArgGlu: 3.879 ± 0.097
2.082ArgPhe: 2.082 ± 0.072
3.424ArgGly: 3.424 ± 0.081
1.156ArgHis: 1.156 ± 0.047
3.487ArgIle: 3.487 ± 0.08
2.527ArgLys: 2.527 ± 0.081
5.029ArgLeu: 5.029 ± 0.115
1.719ArgMet: 1.719 ± 0.068
1.686ArgAsn: 1.686 ± 0.061
1.927ArgPro: 1.927 ± 0.066
1.834ArgGln: 1.834 ± 0.064
3.481ArgArg: 3.481 ± 0.081
3.088ArgSer: 3.088 ± 0.089
2.875ArgThr: 2.875 ± 0.075
3.852ArgVal: 3.852 ± 0.098
0.559ArgTrp: 0.559 ± 0.037
1.628ArgTyr: 1.628 ± 0.06
0.0ArgXaa: 0.0 ± 0.0
Ser
6.161SerAla: 6.161 ± 0.103
0.932SerCys: 0.932 ± 0.049
4.015SerAsp: 4.015 ± 0.093
4.04SerGlu: 4.04 ± 0.092
2.791SerPhe: 2.791 ± 0.068
5.322SerGly: 5.322 ± 0.101
1.445SerHis: 1.445 ± 0.058
3.768SerIle: 3.768 ± 0.082
2.962SerLys: 2.962 ± 0.077
5.87SerLeu: 5.87 ± 0.118
1.599SerMet: 1.599 ± 0.057
2.104SerAsn: 2.104 ± 0.069
2.245SerPro: 2.245 ± 0.063
2.191SerGln: 2.191 ± 0.08
3.45SerArg: 3.45 ± 0.093
4.365SerSer: 4.365 ± 0.115
3.535SerThr: 3.535 ± 0.103
5.027SerVal: 5.027 ± 0.114
0.748SerTrp: 0.748 ± 0.042
2.032SerTyr: 2.032 ± 0.074
0.0SerXaa: 0.0 ± 0.0
Thr
5.085ThrAla: 5.085 ± 0.114
0.921ThrCys: 0.921 ± 0.049
3.395ThrAsp: 3.395 ± 0.085
3.199ThrGlu: 3.199 ± 0.089
2.484ThrPhe: 2.484 ± 0.081
4.51ThrGly: 4.51 ± 0.127
1.529ThrHis: 1.529 ± 0.067
3.593ThrIle: 3.593 ± 0.097
2.673ThrLys: 2.673 ± 0.078
5.635ThrLeu: 5.635 ± 0.099
1.235ThrMet: 1.235 ± 0.055
2.043ThrAsn: 2.043 ± 0.085
3.071ThrPro: 3.071 ± 0.084
2.03ThrGln: 2.03 ± 0.067
2.743ThrArg: 2.743 ± 0.086
3.98ThrSer: 3.98 ± 0.117
3.739ThrThr: 3.739 ± 0.124
4.635ThrVal: 4.635 ± 0.096
0.61ThrTrp: 0.61 ± 0.042
1.956ThrTyr: 1.956 ± 0.059
0.0ThrXaa: 0.0 ± 0.0
Val
7.636ValAla: 7.636 ± 0.144
1.321ValCys: 1.321 ± 0.05
4.807ValAsp: 4.807 ± 0.1
4.572ValGlu: 4.572 ± 0.102
3.149ValPhe: 3.149 ± 0.084
5.338ValGly: 5.338 ± 0.12
1.513ValHis: 1.513 ± 0.056
4.697ValIle: 4.697 ± 0.097
3.248ValLys: 3.248 ± 0.083
7.439ValLeu: 7.439 ± 0.134
1.925ValMet: 1.925 ± 0.068
2.383ValAsn: 2.383 ± 0.077
3.207ValPro: 3.207 ± 0.08
2.174ValGln: 2.174 ± 0.065
3.949ValArg: 3.949 ± 0.094
5.666ValSer: 5.666 ± 0.125
4.506ValThr: 4.506 ± 0.111
6.439ValVal: 6.439 ± 0.133
0.701ValTrp: 0.701 ± 0.043
2.034ValTyr: 2.034 ± 0.07
0.0ValXaa: 0.0 ± 0.0
Trp
0.769TrpAla: 0.769 ± 0.046
0.173TrpCys: 0.173 ± 0.021
0.655TrpAsp: 0.655 ± 0.044
0.575TrpGlu: 0.575 ± 0.036
0.501TrpPhe: 0.501 ± 0.036
0.711TrpGly: 0.711 ± 0.04
0.227TrpHis: 0.227 ± 0.02
0.614TrpIle: 0.614 ± 0.04
0.515TrpLys: 0.515 ± 0.032
1.014TrpLeu: 1.014 ± 0.051
0.272TrpMet: 0.272 ± 0.025
0.433TrpAsn: 0.433 ± 0.031
0.406TrpPro: 0.406 ± 0.032
0.453TrpGln: 0.453 ± 0.03
0.554TrpArg: 0.554 ± 0.037
0.616TrpSer: 0.616 ± 0.038
0.532TrpThr: 0.532 ± 0.033
0.625TrpVal: 0.625 ± 0.041
0.144TrpTrp: 0.144 ± 0.018
0.357TrpTyr: 0.357 ± 0.042
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.949TyrAla: 2.949 ± 0.076
0.402TyrCys: 0.402 ± 0.026
2.047TyrAsp: 2.047 ± 0.064
1.917TyrGlu: 1.917 ± 0.063
1.251TyrPhe: 1.251 ± 0.051
2.416TyrGly: 2.416 ± 0.067
0.67TyrHis: 0.67 ± 0.036
1.515TyrIle: 1.515 ± 0.059
1.239TyrLys: 1.239 ± 0.057
2.89TyrLeu: 2.89 ± 0.086
0.612TyrMet: 0.612 ± 0.034
0.979TyrAsn: 0.979 ± 0.046
1.148TyrPro: 1.148 ± 0.052
1.049TyrGln: 1.049 ± 0.045
1.585TyrArg: 1.585 ± 0.054
1.597TyrSer: 1.597 ± 0.056
1.779TyrThr: 1.779 ± 0.069
2.228TyrVal: 2.228 ± 0.064
0.243TyrTrp: 0.243 ± 0.027
0.895TyrTyr: 0.895 ± 0.049
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1548 proteins (485172 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski