Amino acid dipepetide frequency for Salmonella phage Felix O1 (isolate Felix O1-VT1) (Bacteriophage Felix O1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.723AlaAla: 4.723 ± 0.549
0.564AlaCys: 0.564 ± 0.141
3.596AlaAsp: 3.596 ± 0.3
3.515AlaGlu: 3.515 ± 0.342
2.603AlaPhe: 2.603 ± 0.266
4.562AlaGly: 4.562 ± 0.417
1.476AlaHis: 1.476 ± 0.196
4.267AlaIle: 4.267 ± 0.321
4.964AlaLys: 4.964 ± 0.423
5.635AlaLeu: 5.635 ± 0.419
2.254AlaMet: 2.254 ± 0.296
3.489AlaAsn: 3.489 ± 0.351
1.717AlaPro: 1.717 ± 0.196
2.496AlaGln: 2.496 ± 0.308
2.308AlaArg: 2.308 ± 0.269
4.267AlaSer: 4.267 ± 0.479
4.347AlaThr: 4.347 ± 0.48
5.179AlaVal: 5.179 ± 0.402
0.778AlaTrp: 0.778 ± 0.145
2.442AlaTyr: 2.442 ± 0.29
0.0AlaXaa: 0.0 ± 0.0
Cys
0.751CysAla: 0.751 ± 0.186
0.564CysCys: 0.564 ± 0.161
0.564CysAsp: 0.564 ± 0.102
1.02CysGlu: 1.02 ± 0.152
0.966CysPhe: 0.966 ± 0.188
1.154CysGly: 1.154 ± 0.186
0.59CysHis: 0.59 ± 0.142
1.261CysIle: 1.261 ± 0.203
1.476CysLys: 1.476 ± 0.193
1.556CysLeu: 1.556 ± 0.213
0.429CysMet: 0.429 ± 0.103
1.1CysAsn: 1.1 ± 0.177
0.59CysPro: 0.59 ± 0.145
0.483CysGln: 0.483 ± 0.13
0.886CysArg: 0.886 ± 0.153
1.61CysSer: 1.61 ± 0.245
0.751CysThr: 0.751 ± 0.121
1.395CysVal: 1.395 ± 0.186
0.081CysTrp: 0.081 ± 0.044
0.751CysTyr: 0.751 ± 0.139
0.0CysXaa: 0.0 ± 0.0
Asp
4.025AspAla: 4.025 ± 0.378
0.939AspCys: 0.939 ± 0.143
2.952AspAsp: 2.952 ± 0.277
3.945AspGlu: 3.945 ± 0.33
3.408AspPhe: 3.408 ± 0.271
3.945AspGly: 3.945 ± 0.297
0.698AspHis: 0.698 ± 0.14
3.73AspIle: 3.73 ± 0.345
3.757AspLys: 3.757 ± 0.311
4.374AspLeu: 4.374 ± 0.332
1.234AspMet: 1.234 ± 0.187
3.408AspAsn: 3.408 ± 0.265
1.583AspPro: 1.583 ± 0.24
0.537AspGln: 0.537 ± 0.112
1.825AspArg: 1.825 ± 0.18
4.186AspSer: 4.186 ± 0.292
3.167AspThr: 3.167 ± 0.29
4.32AspVal: 4.32 ± 0.412
1.073AspTrp: 1.073 ± 0.201
2.2AspTyr: 2.2 ± 0.26
0.0AspXaa: 0.0 ± 0.0
Glu
4.938GluAla: 4.938 ± 0.604
0.59GluCys: 0.59 ± 0.128
3.462GluAsp: 3.462 ± 0.327
5.045GluGlu: 5.045 ± 0.51
2.496GluPhe: 2.496 ± 0.27
3.918GluGly: 3.918 ± 0.398
1.53GluHis: 1.53 ± 0.19
4.025GluIle: 4.025 ± 0.417
4.535GluLys: 4.535 ± 0.335
5.689GluLeu: 5.689 ± 0.412
2.335GluMet: 2.335 ± 0.227
2.925GluAsn: 2.925 ± 0.265
1.852GluPro: 1.852 ± 0.27
2.12GluGln: 2.12 ± 0.248
2.925GluArg: 2.925 ± 0.249
3.811GluSer: 3.811 ± 0.364
3.167GluThr: 3.167 ± 0.293
4.186GluVal: 4.186 ± 0.299
0.698GluTrp: 0.698 ± 0.131
1.959GluTyr: 1.959 ± 0.233
0.0GluXaa: 0.0 ± 0.0
Phe
2.764PheAla: 2.764 ± 0.343
0.966PheCys: 0.966 ± 0.17
2.764PheAsp: 2.764 ± 0.246
3.006PheGlu: 3.006 ± 0.287
1.905PhePhe: 1.905 ± 0.248
2.844PheGly: 2.844 ± 0.264
1.127PheHis: 1.127 ± 0.142
3.006PheIle: 3.006 ± 0.336
3.918PheLys: 3.918 ± 0.335
3.757PheLeu: 3.757 ± 0.325
1.154PheMet: 1.154 ± 0.158
2.522PheAsn: 2.522 ± 0.277
1.181PhePro: 1.181 ± 0.168
1.664PheGln: 1.664 ± 0.181
1.583PheArg: 1.583 ± 0.219
3.757PheSer: 3.757 ± 0.368
3.059PheThr: 3.059 ± 0.29
2.871PheVal: 2.871 ± 0.273
0.429PheTrp: 0.429 ± 0.098
2.013PheTyr: 2.013 ± 0.261
0.0PheXaa: 0.0 ± 0.0
Gly
4.025GlyAla: 4.025 ± 0.395
1.073GlyCys: 1.073 ± 0.187
2.952GlyAsp: 2.952 ± 0.319
4.052GlyGlu: 4.052 ± 0.359
3.14GlyPhe: 3.14 ± 0.276
3.73GlyGly: 3.73 ± 0.388
1.234GlyHis: 1.234 ± 0.169
3.945GlyIle: 3.945 ± 0.342
5.823GlyLys: 5.823 ± 0.369
4.857GlyLeu: 4.857 ± 0.371
1.073GlyMet: 1.073 ± 0.188
2.522GlyAsn: 2.522 ± 0.273
0.027GlyPro: 0.027 ± 0.024
1.852GlyGln: 1.852 ± 0.244
2.415GlyArg: 2.415 ± 0.209
3.676GlySer: 3.676 ± 0.384
3.247GlyThr: 3.247 ± 0.372
4.777GlyVal: 4.777 ± 0.322
0.912GlyTrp: 0.912 ± 0.138
2.63GlyTyr: 2.63 ± 0.262
0.0GlyXaa: 0.0 ± 0.0
His
0.966HisAla: 0.966 ± 0.126
0.537HisCys: 0.537 ± 0.128
0.966HisAsp: 0.966 ± 0.159
1.288HisGlu: 1.288 ± 0.175
1.234HisPhe: 1.234 ± 0.2
0.886HisGly: 0.886 ± 0.171
0.966HisHis: 0.966 ± 0.178
1.422HisIle: 1.422 ± 0.189
1.422HisLys: 1.422 ± 0.178
2.522HisLeu: 2.522 ± 0.263
0.751HisMet: 0.751 ± 0.126
0.993HisAsn: 0.993 ± 0.15
0.886HisPro: 0.886 ± 0.152
0.59HisGln: 0.59 ± 0.11
1.154HisArg: 1.154 ± 0.186
1.637HisSer: 1.637 ± 0.258
1.449HisThr: 1.449 ± 0.33
1.395HisVal: 1.395 ± 0.208
0.295HisTrp: 0.295 ± 0.094
1.127HisTyr: 1.127 ± 0.175
0.0HisXaa: 0.0 ± 0.0
Ile
4.294IleAla: 4.294 ± 0.352
1.449IleCys: 1.449 ± 0.198
3.972IleAsp: 3.972 ± 0.347
3.864IleGlu: 3.864 ± 0.316
3.113IlePhe: 3.113 ± 0.318
2.844IleGly: 2.844 ± 0.294
1.181IleHis: 1.181 ± 0.167
3.73IleIle: 3.73 ± 0.373
4.857IleLys: 4.857 ± 0.396
5.286IleLeu: 5.286 ± 0.428
1.798IleMet: 1.798 ± 0.26
3.247IleAsn: 3.247 ± 0.296
2.335IlePro: 2.335 ± 0.262
1.825IleGln: 1.825 ± 0.201
2.657IleArg: 2.657 ± 0.31
4.562IleSer: 4.562 ± 0.359
4.052IleThr: 4.052 ± 0.344
3.676IleVal: 3.676 ± 0.342
0.698IleTrp: 0.698 ± 0.119
2.737IleTyr: 2.737 ± 0.262
0.0IleXaa: 0.0 ± 0.0
Lys
5.206LysAla: 5.206 ± 0.429
1.261LysCys: 1.261 ± 0.214
4.535LysAsp: 4.535 ± 0.367
5.582LysGlu: 5.582 ± 0.494
2.791LysPhe: 2.791 ± 0.281
5.206LysGly: 5.206 ± 0.436
1.53LysHis: 1.53 ± 0.222
4.589LysIle: 4.589 ± 0.289
5.501LysLys: 5.501 ± 0.507
6.279LysLeu: 6.279 ± 0.355
2.791LysMet: 2.791 ± 0.286
3.676LysAsn: 3.676 ± 0.299
2.335LysPro: 2.335 ± 0.248
2.871LysGln: 2.871 ± 0.293
3.489LysArg: 3.489 ± 0.255
4.884LysSer: 4.884 ± 0.364
5.367LysThr: 5.367 ± 0.388
6.306LysVal: 6.306 ± 0.501
0.671LysTrp: 0.671 ± 0.133
2.603LysTyr: 2.603 ± 0.337
0.0LysXaa: 0.0 ± 0.0
Leu
5.394LeuAla: 5.394 ± 0.426
1.556LeuCys: 1.556 ± 0.236
5.286LeuAsp: 5.286 ± 0.377
5.608LeuGlu: 5.608 ± 0.403
3.676LeuPhe: 3.676 ± 0.284
3.676LeuGly: 3.676 ± 0.256
2.442LeuHis: 2.442 ± 0.301
4.267LeuIle: 4.267 ± 0.352
7.406LeuLys: 7.406 ± 0.479
7.863LeuLeu: 7.863 ± 0.583
2.979LeuMet: 2.979 ± 0.33
4.589LeuAsn: 4.589 ± 0.338
3.811LeuPro: 3.811 ± 0.344
3.945LeuGln: 3.945 ± 0.318
4.159LeuArg: 4.159 ± 0.311
7.004LeuSer: 7.004 ± 0.503
5.421LeuThr: 5.421 ± 0.327
4.535LeuVal: 4.535 ± 0.342
1.02LeuTrp: 1.02 ± 0.149
3.059LeuTyr: 3.059 ± 0.293
0.0LeuXaa: 0.0 ± 0.0
Met
1.878MetAla: 1.878 ± 0.232
0.59MetCys: 0.59 ± 0.137
1.288MetAsp: 1.288 ± 0.19
1.61MetGlu: 1.61 ± 0.206
1.556MetPhe: 1.556 ± 0.214
1.556MetGly: 1.556 ± 0.171
0.403MetHis: 0.403 ± 0.108
2.093MetIle: 2.093 ± 0.245
2.657MetLys: 2.657 ± 0.323
2.657MetLeu: 2.657 ± 0.298
0.59MetMet: 0.59 ± 0.131
1.556MetAsn: 1.556 ± 0.215
0.751MetPro: 0.751 ± 0.173
1.449MetGln: 1.449 ± 0.228
1.61MetArg: 1.61 ± 0.175
2.013MetSer: 2.013 ± 0.221
1.878MetThr: 1.878 ± 0.183
1.61MetVal: 1.61 ± 0.172
0.322MetTrp: 0.322 ± 0.091
0.886MetTyr: 0.886 ± 0.144
0.0MetXaa: 0.0 ± 0.0
Asn
3.703AsnAla: 3.703 ± 0.33
0.939AsnCys: 0.939 ± 0.158
2.147AsnAsp: 2.147 ± 0.242
2.361AsnGlu: 2.361 ± 0.249
2.71AsnPhe: 2.71 ± 0.303
3.73AsnGly: 3.73 ± 0.372
1.53AsnHis: 1.53 ± 0.193
3.22AsnIle: 3.22 ± 0.381
3.703AsnLys: 3.703 ± 0.3
4.803AsnLeu: 4.803 ± 0.386
0.993AsnMet: 0.993 ± 0.194
2.871AsnAsn: 2.871 ± 0.336
2.039AsnPro: 2.039 ± 0.217
1.771AsnGln: 1.771 ± 0.22
1.905AsnArg: 1.905 ± 0.247
4.052AsnSer: 4.052 ± 0.326
2.63AsnThr: 2.63 ± 0.289
3.864AsnVal: 3.864 ± 0.332
0.617AsnTrp: 0.617 ± 0.107
2.12AsnTyr: 2.12 ± 0.225
0.0AsnXaa: 0.0 ± 0.0
Pro
1.986ProAla: 1.986 ± 0.243
0.429ProCys: 0.429 ± 0.101
1.905ProAsp: 1.905 ± 0.251
2.335ProGlu: 2.335 ± 0.267
1.905ProPhe: 1.905 ± 0.209
0.215ProGly: 0.215 ± 0.083
0.644ProHis: 0.644 ± 0.15
1.771ProIle: 1.771 ± 0.204
2.281ProLys: 2.281 ± 0.275
2.818ProLeu: 2.818 ± 0.295
0.912ProMet: 0.912 ± 0.154
1.503ProAsn: 1.503 ± 0.188
1.154ProPro: 1.154 ± 0.188
1.02ProGln: 1.02 ± 0.199
0.859ProArg: 0.859 ± 0.173
3.462ProSer: 3.462 ± 0.342
2.227ProThr: 2.227 ± 0.261
2.227ProVal: 2.227 ± 0.239
0.134ProTrp: 0.134 ± 0.06
1.154ProTyr: 1.154 ± 0.143
0.0ProXaa: 0.0 ± 0.0
Gln
1.986GlnAla: 1.986 ± 0.272
0.456GlnCys: 0.456 ± 0.109
1.476GlnAsp: 1.476 ± 0.177
2.361GlnGlu: 2.361 ± 0.311
1.449GlnPhe: 1.449 ± 0.181
1.476GlnGly: 1.476 ± 0.197
0.644GlnHis: 0.644 ± 0.138
2.2GlnIle: 2.2 ± 0.237
2.818GlnLys: 2.818 ± 0.27
2.63GlnLeu: 2.63 ± 0.304
1.02GlnMet: 1.02 ± 0.169
2.147GlnAsn: 2.147 ± 0.225
1.234GlnPro: 1.234 ± 0.173
1.342GlnGln: 1.342 ± 0.199
2.093GlnArg: 2.093 ± 0.252
2.039GlnSer: 2.039 ± 0.213
2.147GlnThr: 2.147 ± 0.243
2.683GlnVal: 2.683 ± 0.253
0.564GlnTrp: 0.564 ± 0.129
1.664GlnTyr: 1.664 ± 0.214
0.0GlnXaa: 0.0 ± 0.0
Arg
2.335ArgAla: 2.335 ± 0.272
0.912ArgCys: 0.912 ± 0.16
2.898ArgAsp: 2.898 ± 0.264
2.63ArgGlu: 2.63 ± 0.307
1.637ArgPhe: 1.637 ± 0.204
2.335ArgGly: 2.335 ± 0.295
0.966ArgHis: 0.966 ± 0.172
2.925ArgIle: 2.925 ± 0.189
3.059ArgLys: 3.059 ± 0.254
3.972ArgLeu: 3.972 ± 0.376
1.261ArgMet: 1.261 ± 0.19
2.388ArgAsn: 2.388 ± 0.229
1.342ArgPro: 1.342 ± 0.175
1.556ArgGln: 1.556 ± 0.189
2.227ArgArg: 2.227 ± 0.231
2.039ArgSer: 2.039 ± 0.244
2.254ArgThr: 2.254 ± 0.26
2.979ArgVal: 2.979 ± 0.239
0.59ArgTrp: 0.59 ± 0.12
2.2ArgTyr: 2.2 ± 0.259
0.0ArgXaa: 0.0 ± 0.0
Ser
4.481SerAla: 4.481 ± 0.417
1.342SerCys: 1.342 ± 0.235
4.267SerAsp: 4.267 ± 0.349
3.945SerGlu: 3.945 ± 0.313
3.596SerPhe: 3.596 ± 0.31
3.596SerGly: 3.596 ± 0.315
1.744SerHis: 1.744 ± 0.203
4.481SerIle: 4.481 ± 0.394
4.562SerLys: 4.562 ± 0.361
7.299SerLeu: 7.299 ± 0.433
1.932SerMet: 1.932 ± 0.227
3.328SerAsn: 3.328 ± 0.295
2.066SerPro: 2.066 ± 0.257
2.496SerGln: 2.496 ± 0.311
3.167SerArg: 3.167 ± 0.251
5.904SerSer: 5.904 ± 0.561
3.891SerThr: 3.891 ± 0.436
5.582SerVal: 5.582 ± 0.387
0.886SerTrp: 0.886 ± 0.158
3.14SerTyr: 3.14 ± 0.297
0.0SerXaa: 0.0 ± 0.0
Thr
3.945ThrAla: 3.945 ± 0.387
1.073ThrCys: 1.073 ± 0.225
3.274ThrAsp: 3.274 ± 0.285
2.952ThrGlu: 2.952 ± 0.268
3.167ThrPhe: 3.167 ± 0.296
4.911ThrGly: 4.911 ± 0.426
1.369ThrHis: 1.369 ± 0.225
4.186ThrIle: 4.186 ± 0.325
4.535ThrLys: 4.535 ± 0.519
5.635ThrLeu: 5.635 ± 0.393
1.315ThrMet: 1.315 ± 0.19
2.683ThrAsn: 2.683 ± 0.266
2.361ThrPro: 2.361 ± 0.273
2.174ThrGln: 2.174 ± 0.271
2.2ThrArg: 2.2 ± 0.214
4.347ThrSer: 4.347 ± 0.446
4.025ThrThr: 4.025 ± 0.437
5.179ThrVal: 5.179 ± 0.416
0.51ThrTrp: 0.51 ± 0.121
2.844ThrTyr: 2.844 ± 0.276
0.0ThrXaa: 0.0 ± 0.0
Val
5.233ValAla: 5.233 ± 0.412
1.449ValCys: 1.449 ± 0.197
4.052ValAsp: 4.052 ± 0.315
3.945ValGlu: 3.945 ± 0.387
2.683ValPhe: 2.683 ± 0.259
4.267ValGly: 4.267 ± 0.393
1.395ValHis: 1.395 ± 0.207
4.294ValIle: 4.294 ± 0.418
5.93ValLys: 5.93 ± 0.402
5.099ValLeu: 5.099 ± 0.381
2.469ValMet: 2.469 ± 0.255
4.052ValAsn: 4.052 ± 0.336
2.147ValPro: 2.147 ± 0.246
2.174ValGln: 2.174 ± 0.252
2.683ValArg: 2.683 ± 0.264
4.75ValSer: 4.75 ± 0.317
5.608ValThr: 5.608 ± 0.451
4.642ValVal: 4.642 ± 0.387
0.805ValTrp: 0.805 ± 0.175
2.63ValTyr: 2.63 ± 0.233
0.0ValXaa: 0.0 ± 0.0
Trp
0.268TrpAla: 0.268 ± 0.085
0.295TrpCys: 0.295 ± 0.083
0.725TrpAsp: 0.725 ± 0.161
0.698TrpGlu: 0.698 ± 0.142
0.59TrpPhe: 0.59 ± 0.14
0.59TrpGly: 0.59 ± 0.115
0.081TrpHis: 0.081 ± 0.046
0.564TrpIle: 0.564 ± 0.126
1.127TrpLys: 1.127 ± 0.171
1.234TrpLeu: 1.234 ± 0.183
0.403TrpMet: 0.403 ± 0.106
0.832TrpAsn: 0.832 ± 0.168
0.215TrpPro: 0.215 ± 0.066
0.51TrpGln: 0.51 ± 0.12
0.51TrpArg: 0.51 ± 0.125
0.832TrpSer: 0.832 ± 0.167
0.564TrpThr: 0.564 ± 0.121
0.859TrpVal: 0.859 ± 0.138
0.188TrpTrp: 0.188 ± 0.066
0.564TrpTyr: 0.564 ± 0.112
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.281TyrAla: 2.281 ± 0.251
0.993TyrCys: 0.993 ± 0.148
2.227TyrAsp: 2.227 ± 0.24
2.442TyrGlu: 2.442 ± 0.228
1.664TyrPhe: 1.664 ± 0.19
2.522TyrGly: 2.522 ± 0.246
0.939TyrHis: 0.939 ± 0.17
2.2TyrIle: 2.2 ± 0.201
3.14TyrLys: 3.14 ± 0.276
3.73TyrLeu: 3.73 ± 0.292
1.234TyrMet: 1.234 ± 0.175
1.878TyrAsn: 1.878 ± 0.208
1.342TyrPro: 1.342 ± 0.205
1.556TyrGln: 1.556 ± 0.247
1.852TyrArg: 1.852 ± 0.213
2.871TyrSer: 2.871 ± 0.232
3.435TyrThr: 3.435 ± 0.376
2.039TyrVal: 2.039 ± 0.22
0.376TyrTrp: 0.376 ± 0.094
1.637TyrTyr: 1.637 ± 0.224
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 247 proteins (37266 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski