Amino acid dipepetide frequency for Perca flavescens (American yellow perch) (Morone flavescens)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.553AlaAla: 6.553 ± 0.044	1.293AlaCys: 1.293 ± 0.013	3.262AlaAsp: 3.262 ± 0.019	4.768AlaGlu: 4.768 ± 0.032	2.326AlaPhe: 2.326 ± 0.016	4.499AlaGly: 4.499 ± 0.028	1.524AlaHis: 1.524 ± 0.012	2.666AlaIle: 2.666 ± 0.017	3.413AlaLys: 3.413 ± 0.026	6.531AlaLeu: 6.531 ± 0.033	1.647AlaMet: 1.647 ± 0.016	2.24AlaAsn: 2.24 ± 0.015	3.612AlaPro: 3.612 ± 0.026	3.003AlaGln: 3.003 ± 0.024	3.194AlaArg: 3.194 ± 0.018	5.622AlaSer: 5.622 ± 0.025	3.616AlaThr: 3.616 ± 0.024	5.003AlaVal: 5.003 ± 0.025	0.665AlaTrp: 0.665 ± 0.009	1.482AlaTyr: 1.482 ± 0.013	0.0AlaXaa: 0.0 ± 0.0
Cys	1.177CysAla: 1.177 ± 0.013	0.644CysCys: 0.644 ± 0.011	1.131CysAsp: 1.131 ± 0.016	1.243CysGlu: 1.243 ± 0.017	0.825CysPhe: 0.825 ± 0.009	1.522CysGly: 1.522 ± 0.019	0.648CysHis: 0.648 ± 0.01	0.924CysIle: 0.924 ± 0.01	1.101CysLys: 1.101 ± 0.012	2.12CysLeu: 2.12 ± 0.015	0.468CysMet: 0.468 ± 0.007	0.837CysAsn: 0.837 ± 0.011	1.337CysPro: 1.337 ± 0.021	1.064CysGln: 1.064 ± 0.013	1.294CysArg: 1.294 ± 0.013	2.142CysSer: 2.142 ± 0.021	1.174CysThr: 1.174 ± 0.013	1.55CysVal: 1.55 ± 0.026	0.29CysTrp: 0.29 ± 0.005	0.6CysTyr: 0.6 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	3.003AspAla: 3.003 ± 0.017	1.161AspCys: 1.161 ± 0.015	3.191AspAsp: 3.191 ± 0.031	3.79AspGlu: 3.79 ± 0.027	2.067AspPhe: 2.067 ± 0.015	3.722AspGly: 3.722 ± 0.028	1.19AspHis: 1.19 ± 0.011	2.673AspIle: 2.673 ± 0.018	2.735AspLys: 2.735 ± 0.019	4.865AspLeu: 4.865 ± 0.023	1.335AspMet: 1.335 ± 0.011	2.003AspAsn: 2.003 ± 0.015	2.879AspPro: 2.879 ± 0.016	2.024AspGln: 2.024 ± 0.014	2.828AspArg: 2.828 ± 0.021	4.613AspSer: 4.613 ± 0.025	2.76AspThr: 2.76 ± 0.015	3.279AspVal: 3.279 ± 0.02	0.683AspTrp: 0.683 ± 0.009	1.525AspTyr: 1.525 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.833GluAla: 4.833 ± 0.031	1.227GluCys: 1.227 ± 0.017	4.516GluAsp: 4.516 ± 0.026	8.349GluGlu: 8.349 ± 0.078	1.874GluPhe: 1.874 ± 0.015	4.278GluGly: 4.278 ± 0.024	1.463GluHis: 1.463 ± 0.012	2.787GluIle: 2.787 ± 0.02	4.677GluLys: 4.677 ± 0.03	6.196GluLeu: 6.196 ± 0.042	1.779GluMet: 1.779 ± 0.015	2.66GluAsn: 2.66 ± 0.019	2.91GluPro: 2.91 ± 0.025	3.173GluGln: 3.173 ± 0.031	4.399GluArg: 4.399 ± 0.032	4.456GluSer: 4.456 ± 0.023	3.493GluThr: 3.493 ± 0.021	4.355GluVal: 4.355 ± 0.022	0.675GluTrp: 0.675 ± 0.008	1.552GluTyr: 1.552 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	1.848PheAla: 1.848 ± 0.015	0.887PheCys: 0.887 ± 0.011	1.69PheAsp: 1.69 ± 0.012	1.799PheGlu: 1.799 ± 0.014	1.473PhePhe: 1.473 ± 0.015	2.135PheGly: 2.135 ± 0.018	0.977PheHis: 0.977 ± 0.01	1.783PheIle: 1.783 ± 0.016	1.734PheLys: 1.734 ± 0.015	3.677PheLeu: 3.677 ± 0.025	0.791PheMet: 0.791 ± 0.009	1.445PheAsn: 1.445 ± 0.015	1.783PhePro: 1.783 ± 0.014	1.578PheGln: 1.578 ± 0.013	1.816PheArg: 1.816 ± 0.019	3.279PheSer: 3.279 ± 0.019	2.218PheThr: 2.218 ± 0.015	2.106PheVal: 2.106 ± 0.016	0.441PheTrp: 0.441 ± 0.006	1.147PheTyr: 1.147 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	4.167GlyAla: 4.167 ± 0.025	1.296GlyCys: 1.296 ± 0.013	3.311GlyAsp: 3.311 ± 0.02	4.244GlyGlu: 4.244 ± 0.031	2.379GlyPhe: 2.379 ± 0.019	5.786GlyGly: 5.786 ± 0.047	1.682GlyHis: 1.682 ± 0.014	2.548GlyIle: 2.548 ± 0.016	3.558GlyLys: 3.558 ± 0.025	5.585GlyLeu: 5.585 ± 0.029	1.514GlyMet: 1.514 ± 0.013	2.484GlyAsn: 2.484 ± 0.018	3.411GlyPro: 3.411 ± 0.038	2.86GlyGln: 2.86 ± 0.018	3.755GlyArg: 3.755 ± 0.024	5.879GlySer: 5.879 ± 0.032	3.388GlyThr: 3.388 ± 0.023	4.064GlyVal: 4.064 ± 0.022	0.773GlyTrp: 0.773 ± 0.011	1.832GlyTyr: 1.832 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	1.386HisAla: 1.386 ± 0.013	0.741HisCys: 0.741 ± 0.008	0.982HisAsp: 0.982 ± 0.01	1.169HisGlu: 1.169 ± 0.009	1.027HisPhe: 1.027 ± 0.009	1.598HisGly: 1.598 ± 0.014	1.116HisHis: 1.116 ± 0.017	1.278HisIle: 1.278 ± 0.011	1.277HisLys: 1.277 ± 0.012	2.642HisLeu: 2.642 ± 0.017	0.665HisMet: 0.665 ± 0.007	1.059HisAsn: 1.059 ± 0.01	1.617HisPro: 1.617 ± 0.016	1.321HisGln: 1.321 ± 0.013	1.67HisArg: 1.67 ± 0.014	2.515HisSer: 2.515 ± 0.02	1.609HisThr: 1.609 ± 0.017	1.429HisVal: 1.429 ± 0.011	0.334HisTrp: 0.334 ± 0.006	0.845HisTyr: 0.845 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	2.442IleAla: 2.442 ± 0.018	1.009IleCys: 1.009 ± 0.01	2.044IleAsp: 2.044 ± 0.015	2.341IleGlu: 2.341 ± 0.02	1.665IlePhe: 1.665 ± 0.017	2.295IleGly: 2.295 ± 0.016	1.212IleHis: 1.212 ± 0.011	2.276IleIle: 2.276 ± 0.019	2.467IleLys: 2.467 ± 0.016	4.082IleLeu: 4.082 ± 0.023	1.042IleMet: 1.042 ± 0.01	1.88IleAsn: 1.88 ± 0.016	2.456IlePro: 2.456 ± 0.017	2.189IleGln: 2.189 ± 0.017	2.35IleArg: 2.35 ± 0.016	3.689IleSer: 3.689 ± 0.02	2.744IleThr: 2.744 ± 0.021	2.471IleVal: 2.471 ± 0.018	0.454IleTrp: 0.454 ± 0.006	1.291IleTyr: 1.291 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	3.804LysAla: 3.804 ± 0.025	0.981LysCys: 0.981 ± 0.012	3.262LysAsp: 3.262 ± 0.022	4.773LysGlu: 4.773 ± 0.036	1.501LysPhe: 1.501 ± 0.014	3.243LysGly: 3.243 ± 0.026	1.398LysHis: 1.398 ± 0.011	2.371LysIle: 2.371 ± 0.016	4.486LysLys: 4.486 ± 0.037	4.854LysLeu: 4.854 ± 0.03	1.509LysMet: 1.509 ± 0.015	2.165LysAsn: 2.165 ± 0.016	2.939LysPro: 2.939 ± 0.021	2.533LysGln: 2.533 ± 0.019	3.482LysArg: 3.482 ± 0.022	3.772LysSer: 3.772 ± 0.023	3.229LysThr: 3.229 ± 0.018	3.481LysVal: 3.481 ± 0.022	0.57LysTrp: 0.57 ± 0.008	1.43LysTyr: 1.43 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	6.14LeuAla: 6.14 ± 0.026	2.171LeuCys: 2.171 ± 0.016	4.858LeuAsp: 4.858 ± 0.023	6.396LeuGlu: 6.396 ± 0.043	3.238LeuPhe: 3.238 ± 0.023	5.203LeuGly: 5.203 ± 0.025	2.7LeuHis: 2.7 ± 0.019	3.641LeuIle: 3.641 ± 0.023	5.499LeuLys: 5.499 ± 0.027	9.994LeuLeu: 9.994 ± 0.055	2.12LeuMet: 2.12 ± 0.015	3.525LeuAsn: 3.525 ± 0.021	5.387LeuPro: 5.387 ± 0.029	5.534LeuGln: 5.534 ± 0.041	5.64LeuArg: 5.64 ± 0.033	8.381LeuSer: 8.381 ± 0.034	5.225LeuThr: 5.225 ± 0.024	5.397LeuVal: 5.397 ± 0.024	1.059LeuTrp: 1.059 ± 0.01	2.519LeuTyr: 2.519 ± 0.018	0.0LeuXaa: 0.0 ± 0.0
Met	2.014MetAla: 2.014 ± 0.013	0.477MetCys: 0.477 ± 0.007	1.505MetAsp: 1.505 ± 0.013	2.053MetGlu: 2.053 ± 0.015	0.836MetPhe: 0.836 ± 0.009	1.479MetGly: 1.479 ± 0.013	0.497MetHis: 0.497 ± 0.007	0.857MetIle: 0.857 ± 0.009	1.48MetLys: 1.48 ± 0.013	2.108MetLeu: 2.108 ± 0.016	0.736MetMet: 0.736 ± 0.009	0.888MetAsn: 0.888 ± 0.011	1.116MetPro: 1.116 ± 0.014	1.016MetGln: 1.016 ± 0.01	1.184MetArg: 1.184 ± 0.009	1.953MetSer: 1.953 ± 0.015	1.282MetThr: 1.282 ± 0.01	1.555MetVal: 1.555 ± 0.011	0.267MetTrp: 0.267 ± 0.005	0.615MetTyr: 0.615 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.166AsnAla: 2.166 ± 0.017	0.868AsnCys: 0.868 ± 0.014	1.643AsnAsp: 1.643 ± 0.014	2.052AsnGlu: 2.052 ± 0.015	1.35AsnPhe: 1.35 ± 0.012	2.762AsnGly: 2.762 ± 0.023	1.023AsnHis: 1.023 ± 0.012	2.082AsnIle: 2.082 ± 0.013	2.197AsnLys: 2.197 ± 0.015	3.506AsnLeu: 3.506 ± 0.018	1.07AsnMet: 1.07 ± 0.011	1.849AsnAsn: 1.849 ± 0.017	2.224AsnPro: 2.224 ± 0.015	1.753AsnGln: 1.753 ± 0.015	2.001AsnArg: 2.001 ± 0.012	3.228AsnSer: 3.228 ± 0.02	2.297AsnThr: 2.297 ± 0.015	2.281AsnVal: 2.281 ± 0.017	0.433AsnTrp: 0.433 ± 0.006	1.116AsnTyr: 1.116 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	4.386ProAla: 4.386 ± 0.027	1.128ProCys: 1.128 ± 0.015	2.929ProAsp: 2.929 ± 0.018	3.817ProGlu: 3.817 ± 0.024	1.745ProPhe: 1.745 ± 0.016	4.209ProGly: 4.209 ± 0.047	1.545ProHis: 1.545 ± 0.015	1.891ProIle: 1.891 ± 0.016	2.589ProLys: 2.589 ± 0.022	4.911ProLeu: 4.911 ± 0.025	1.075ProMet: 1.075 ± 0.011	1.959ProAsn: 1.959 ± 0.014	5.612ProPro: 5.612 ± 0.046	2.756ProGln: 2.756 ± 0.023	2.814ProArg: 2.814 ± 0.02	5.755ProSer: 5.755 ± 0.033	3.191ProThr: 3.191 ± 0.023	3.809ProVal: 3.809 ± 0.023	0.55ProTrp: 0.55 ± 0.008	1.403ProTyr: 1.403 ± 0.012	0.0ProXaa: 0.0 ± 0.0
Gln	3.267GlnAla: 3.267 ± 0.025	0.978GlnCys: 0.978 ± 0.015	2.401GlnAsp: 2.401 ± 0.016	3.553GlnGlu: 3.553 ± 0.031	1.321GlnPhe: 1.321 ± 0.012	2.839GlnGly: 2.839 ± 0.022	1.435GlnHis: 1.435 ± 0.013	1.881GlnIle: 1.881 ± 0.013	2.56GlnLys: 2.56 ± 0.021	4.607GlnLeu: 4.607 ± 0.037	1.16GlnMet: 1.16 ± 0.012	1.74GlnAsn: 1.74 ± 0.013	2.739GlnPro: 2.739 ± 0.023	3.659GlnGln: 3.659 ± 0.054	3.217GlnArg: 3.217 ± 0.021	3.671GlnSer: 3.671 ± 0.023	2.707GlnThr: 2.707 ± 0.018	2.751GlnVal: 2.751 ± 0.017	0.552GlnTrp: 0.552 ± 0.007	1.216GlnTyr: 1.216 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	3.535ArgAla: 3.535 ± 0.019	1.279ArgCys: 1.279 ± 0.015	3.016ArgAsp: 3.016 ± 0.02	4.062ArgGlu: 4.062 ± 0.03	1.87ArgPhe: 1.87 ± 0.013	3.676ArgGly: 3.676 ± 0.026	1.588ArgHis: 1.588 ± 0.013	2.301ArgIle: 2.301 ± 0.017	3.541ArgLys: 3.541 ± 0.022	5.371ArgLeu: 5.371 ± 0.03	1.331ArgMet: 1.331 ± 0.011	2.076ArgAsn: 2.076 ± 0.013	3.029ArgPro: 3.029 ± 0.023	2.74ArgGln: 2.74 ± 0.019	4.531ArgArg: 4.531 ± 0.03	4.595ArgSer: 4.595 ± 0.026	2.897ArgThr: 2.897 ± 0.016	3.329ArgVal: 3.329 ± 0.023	0.691ArgTrp: 0.691 ± 0.009	1.517ArgTyr: 1.517 ± 0.012	0.0ArgXaa: 0.0 ± 0.0
Ser	5.756SerAla: 5.756 ± 0.024	1.991SerCys: 1.991 ± 0.02	4.403SerAsp: 4.403 ± 0.026	4.969SerGlu: 4.969 ± 0.022	2.999SerPhe: 2.999 ± 0.018	5.674SerGly: 5.674 ± 0.03	2.266SerHis: 2.266 ± 0.016	3.296SerIle: 3.296 ± 0.019	4.021SerLys: 4.021 ± 0.022	8.345SerLeu: 8.345 ± 0.043	1.876SerMet: 1.876 ± 0.012	3.012SerAsn: 3.012 ± 0.019	6.196SerPro: 6.196 ± 0.043	4.082SerGln: 4.082 ± 0.024	4.606SerArg: 4.606 ± 0.025	10.696SerSer: 10.696 ± 0.064	4.951SerThr: 4.951 ± 0.024	5.48SerVal: 5.48 ± 0.023	0.988SerTrp: 0.988 ± 0.011	2.144SerTyr: 2.144 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	4.156ThrAla: 4.156 ± 0.022	1.317ThrCys: 1.317 ± 0.019	2.965ThrAsp: 2.965 ± 0.019	3.832ThrGlu: 3.832 ± 0.023	2.018ThrPhe: 2.018 ± 0.015	3.77ThrGly: 3.77 ± 0.022	1.422ThrHis: 1.422 ± 0.016	2.367ThrIle: 2.367 ± 0.018	2.738ThrLys: 2.738 ± 0.019	5.413ThrLeu: 5.413 ± 0.024	1.268ThrMet: 1.268 ± 0.01	1.982ThrAsn: 1.982 ± 0.015	3.733ThrPro: 3.733 ± 0.022	2.444ThrGln: 2.444 ± 0.018	2.521ThrArg: 2.521 ± 0.016	4.934ThrSer: 4.934 ± 0.029	3.486ThrThr: 3.486 ± 0.031	4.207ThrVal: 4.207 ± 0.026	0.662ThrTrp: 0.662 ± 0.009	1.402ThrTyr: 1.402 ± 0.013	0.0ThrXaa: 0.0 ± 0.0
Val	4.228ValAla: 4.228 ± 0.02	1.721ValCys: 1.721 ± 0.025	3.213ValAsp: 3.213 ± 0.016	4.169ValGlu: 4.169 ± 0.024	2.542ValPhe: 2.542 ± 0.017	3.552ValGly: 3.552 ± 0.019	1.539ValHis: 1.539 ± 0.011	2.867ValIle: 2.867 ± 0.019	3.591ValLys: 3.591 ± 0.025	6.12ValLeu: 6.12 ± 0.027	1.53ValMet: 1.53 ± 0.011	2.433ValAsn: 2.433 ± 0.019	3.334ValPro: 3.334 ± 0.018	2.789ValGln: 2.789 ± 0.017	3.254ValArg: 3.254 ± 0.018	5.319ValSer: 5.319 ± 0.027	4.02ValThr: 4.02 ± 0.035	4.413ValVal: 4.413 ± 0.025	0.77ValTrp: 0.77 ± 0.01	1.78ValTyr: 1.78 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	0.674TrpAla: 0.674 ± 0.008	0.238TrpCys: 0.238 ± 0.005	0.65TrpAsp: 0.65 ± 0.009	0.743TrpGlu: 0.743 ± 0.008	0.442TrpPhe: 0.442 ± 0.007	0.629TrpGly: 0.629 ± 0.01	0.263TrpHis: 0.263 ± 0.005	0.529TrpIle: 0.529 ± 0.007	0.709TrpLys: 0.709 ± 0.008	1.163TrpLeu: 1.163 ± 0.012	0.337TrpMet: 0.337 ± 0.005	0.479TrpAsn: 0.479 ± 0.007	0.44TrpPro: 0.44 ± 0.006	0.48TrpGln: 0.48 ± 0.007	0.772TrpArg: 0.772 ± 0.009	0.945TrpSer: 0.945 ± 0.011	0.716TrpThr: 0.716 ± 0.01	0.682TrpVal: 0.682 ± 0.008	0.188TrpTrp: 0.188 ± 0.004	0.336TrpTyr: 0.336 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.385TyrAla: 1.385 ± 0.012	0.686TyrCys: 0.686 ± 0.009	1.353TyrAsp: 1.353 ± 0.014	1.529TyrGlu: 1.529 ± 0.014	1.108TyrPhe: 1.108 ± 0.009	1.647TyrGly: 1.647 ± 0.013	0.79TyrHis: 0.79 ± 0.009	1.381TyrIle: 1.381 ± 0.014	1.412TyrLys: 1.412 ± 0.014	2.537TyrLeu: 2.537 ± 0.018	0.668TyrMet: 0.668 ± 0.008	1.184TyrAsn: 1.184 ± 0.014	1.323TyrPro: 1.323 ± 0.012	1.254TyrGln: 1.254 ± 0.012	1.644TyrArg: 1.644 ± 0.012	2.31TyrSer: 2.31 ± 0.017	1.633TyrThr: 1.633 ± 0.016	1.541TyrVal: 1.541 ± 0.016	0.369TyrTrp: 0.369 ± 0.008	0.948TyrTyr: 0.948 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 21644 proteins (12322852 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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