Amino acid dipepetide frequency for Rathayibacter tritici

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.122AlaAla: 20.122 ± 0.225	0.707AlaCys: 0.707 ± 0.027	7.959AlaAsp: 7.959 ± 0.103	8.305AlaGlu: 8.305 ± 0.11	3.794AlaPhe: 3.794 ± 0.068	11.912AlaGly: 11.912 ± 0.132	2.456AlaHis: 2.456 ± 0.055	5.208AlaIle: 5.208 ± 0.083	2.405AlaLys: 2.405 ± 0.074	15.146AlaLeu: 15.146 ± 0.162	2.296AlaMet: 2.296 ± 0.052	2.083AlaAsn: 2.083 ± 0.049	6.715AlaPro: 6.715 ± 0.119	3.64AlaGln: 3.64 ± 0.067	9.657AlaArg: 9.657 ± 0.118	8.182AlaSer: 8.182 ± 0.113	7.578AlaThr: 7.578 ± 0.12	12.618AlaVal: 12.618 ± 0.147	1.707AlaTrp: 1.707 ± 0.051	2.243AlaTyr: 2.243 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.701CysAla: 0.701 ± 0.027	0.069CysCys: 0.069 ± 0.008	0.334CysAsp: 0.334 ± 0.018	0.264CysGlu: 0.264 ± 0.018	0.155CysPhe: 0.155 ± 0.013	0.629CysGly: 0.629 ± 0.026	0.094CysHis: 0.094 ± 0.01	0.183CysIle: 0.183 ± 0.014	0.067CysLys: 0.067 ± 0.008	0.487CysLeu: 0.487 ± 0.026	0.07CysMet: 0.07 ± 0.009	0.097CysAsn: 0.097 ± 0.011	0.292CysPro: 0.292 ± 0.018	0.123CysGln: 0.123 ± 0.012	0.396CysArg: 0.396 ± 0.024	0.429CysSer: 0.429 ± 0.023	0.397CysThr: 0.397 ± 0.019	0.488CysVal: 0.488 ± 0.02	0.102CysTrp: 0.102 ± 0.01	0.097CysTyr: 0.097 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	8.337AspAla: 8.337 ± 0.119	0.297AspCys: 0.297 ± 0.017	3.908AspAsp: 3.908 ± 0.084	4.275AspGlu: 4.275 ± 0.08	1.658AspPhe: 1.658 ± 0.046	6.166AspGly: 6.166 ± 0.092	1.14AspHis: 1.14 ± 0.041	2.106AspIle: 2.106 ± 0.056	0.85AspLys: 0.85 ± 0.035	6.004AspLeu: 6.004 ± 0.091	0.66AspMet: 0.66 ± 0.025	0.868AspAsn: 0.868 ± 0.037	4.274AspPro: 4.274 ± 0.085	1.453AspGln: 1.453 ± 0.041	4.563AspArg: 4.563 ± 0.075	3.386AspSer: 3.386 ± 0.069	2.87AspThr: 2.87 ± 0.062	5.597AspVal: 5.597 ± 0.089	0.871AspTrp: 0.871 ± 0.034	1.249AspTyr: 1.249 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	7.04GluAla: 7.04 ± 0.1	0.252GluCys: 0.252 ± 0.016	2.905GluAsp: 2.905 ± 0.057	3.426GluGlu: 3.426 ± 0.069	1.596GluPhe: 1.596 ± 0.051	4.319GluGly: 4.319 ± 0.086	1.55GluHis: 1.55 ± 0.051	2.582GluIle: 2.582 ± 0.058	1.35GluLys: 1.35 ± 0.046	6.63GluLeu: 6.63 ± 0.108	0.856GluMet: 0.856 ± 0.033	1.176GluAsn: 1.176 ± 0.038	3.155GluPro: 3.155 ± 0.062	2.419GluGln: 2.419 ± 0.06	5.9GluArg: 5.9 ± 0.097	3.155GluSer: 3.155 ± 0.065	2.937GluThr: 2.937 ± 0.052	4.493GluVal: 4.493 ± 0.077	0.86GluTrp: 0.86 ± 0.036	1.11GluTyr: 1.11 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	4.052PheAla: 4.052 ± 0.067	0.192PheCys: 0.192 ± 0.014	2.274PheAsp: 2.274 ± 0.052	1.782PheGlu: 1.782 ± 0.052	0.987PhePhe: 0.987 ± 0.033	3.114PheGly: 3.114 ± 0.062	0.579PheHis: 0.579 ± 0.026	0.878PheIle: 0.878 ± 0.038	0.38PheLys: 0.38 ± 0.022	2.779PheLeu: 2.779 ± 0.07	0.36PheMet: 0.36 ± 0.022	0.504PheAsn: 0.504 ± 0.02	1.377PhePro: 1.377 ± 0.039	0.694PheGln: 0.694 ± 0.028	1.806PheArg: 1.806 ± 0.048	1.922PheSer: 1.922 ± 0.047	1.961PheThr: 1.961 ± 0.048	2.764PheVal: 2.764 ± 0.058	0.423PheTrp: 0.423 ± 0.023	0.591PheTyr: 0.591 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	11.124GlyAla: 11.124 ± 0.134	0.599GlyCys: 0.599 ± 0.029	5.023GlyAsp: 5.023 ± 0.068	4.936GlyGlu: 4.936 ± 0.095	3.108GlyPhe: 3.108 ± 0.064	7.942GlyGly: 7.942 ± 0.122	1.781GlyHis: 1.781 ± 0.045	4.254GlyIle: 4.254 ± 0.073	1.94GlyLys: 1.94 ± 0.056	9.029GlyLeu: 9.029 ± 0.11	1.7GlyMet: 1.7 ± 0.046	1.614GlyAsn: 1.614 ± 0.061	3.956GlyPro: 3.956 ± 0.068	2.171GlyGln: 2.171 ± 0.051	7.201GlyArg: 7.201 ± 0.111	6.256GlySer: 6.256 ± 0.082	5.987GlyThr: 5.987 ± 0.097	8.273GlyVal: 8.273 ± 0.106	1.486GlyTrp: 1.486 ± 0.045	2.104GlyTyr: 2.104 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.244HisAla: 2.244 ± 0.051	0.116HisCys: 0.116 ± 0.012	1.266HisAsp: 1.266 ± 0.04	1.157HisGlu: 1.157 ± 0.037	0.55HisPhe: 0.55 ± 0.026	1.922HisGly: 1.922 ± 0.047	0.526HisHis: 0.526 ± 0.028	0.585HisIle: 0.585 ± 0.023	0.209HisLys: 0.209 ± 0.017	2.106HisLeu: 2.106 ± 0.052	0.266HisMet: 0.266 ± 0.019	0.333HisAsn: 0.333 ± 0.021	1.386HisPro: 1.386 ± 0.044	0.471HisGln: 0.471 ± 0.025	1.797HisArg: 1.797 ± 0.046	1.117HisSer: 1.117 ± 0.04	0.9HisThr: 0.9 ± 0.033	1.68HisVal: 1.68 ± 0.054	0.313HisTrp: 0.313 ± 0.018	0.419HisTyr: 0.419 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	6.378IleAla: 6.378 ± 0.087	0.26IleCys: 0.26 ± 0.017	3.242IleAsp: 3.242 ± 0.059	2.78IleGlu: 2.78 ± 0.06	0.921IlePhe: 0.921 ± 0.035	4.364IleGly: 4.364 ± 0.083	0.613IleHis: 0.613 ± 0.029	1.38IleIle: 1.38 ± 0.052	0.695IleLys: 0.695 ± 0.034	3.377IleLeu: 3.377 ± 0.075	0.461IleMet: 0.461 ± 0.023	0.725IleAsn: 0.725 ± 0.029	2.067IlePro: 2.067 ± 0.044	0.905IleGln: 0.905 ± 0.032	2.797IleArg: 2.797 ± 0.065	2.171IleSer: 2.171 ± 0.059	2.61IleThr: 2.61 ± 0.062	4.064IleVal: 4.064 ± 0.076	0.444IleTrp: 0.444 ± 0.021	0.682IleTyr: 0.682 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.112LysAla: 2.112 ± 0.058	0.06LysCys: 0.06 ± 0.008	0.978LysAsp: 0.978 ± 0.045	0.921LysGlu: 0.921 ± 0.035	0.421LysPhe: 0.421 ± 0.022	1.465LysGly: 1.465 ± 0.05	0.399LysHis: 0.399 ± 0.022	0.8LysIle: 0.8 ± 0.033	0.775LysLys: 0.775 ± 0.035	1.591LysLeu: 1.591 ± 0.052	0.309LysMet: 0.309 ± 0.018	0.555LysAsn: 0.555 ± 0.025	1.043LysPro: 1.043 ± 0.041	0.603LysGln: 0.603 ± 0.026	1.489LysArg: 1.489 ± 0.052	0.978LysSer: 0.978 ± 0.038	1.318LysThr: 1.318 ± 0.048	1.456LysVal: 1.456 ± 0.048	0.21LysTrp: 0.21 ± 0.016	0.389LysTyr: 0.389 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	15.658LeuAla: 15.658 ± 0.182	0.596LeuCys: 0.596 ± 0.025	7.008LeuAsp: 7.008 ± 0.099	5.499LeuGlu: 5.499 ± 0.079	2.71LeuPhe: 2.71 ± 0.063	9.624LeuGly: 9.624 ± 0.123	2.066LeuHis: 2.066 ± 0.042	4.106LeuIle: 4.106 ± 0.085	1.532LeuLys: 1.532 ± 0.054	11.37LeuLeu: 11.37 ± 0.17	1.306LeuMet: 1.306 ± 0.04	1.662LeuAsn: 1.662 ± 0.039	5.814LeuPro: 5.814 ± 0.076	2.491LeuGln: 2.491 ± 0.052	8.246LeuArg: 8.246 ± 0.114	6.18LeuSer: 6.18 ± 0.085	6.127LeuThr: 6.127 ± 0.083	9.953LeuVal: 9.953 ± 0.12	1.184LeuTrp: 1.184 ± 0.04	1.622LeuTyr: 1.622 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	1.781MetAla: 1.781 ± 0.053	0.067MetCys: 0.067 ± 0.009	0.746MetAsp: 0.746 ± 0.029	0.565MetGlu: 0.565 ± 0.026	0.415MetPhe: 0.415 ± 0.02	1.056MetGly: 1.056 ± 0.041	0.277MetHis: 0.277 ± 0.017	0.742MetIle: 0.742 ± 0.033	0.358MetLys: 0.358 ± 0.02	1.6MetLeu: 1.6 ± 0.042	0.258MetMet: 0.258 ± 0.021	0.391MetAsn: 0.391 ± 0.02	0.915MetPro: 0.915 ± 0.03	0.454MetGln: 0.454 ± 0.027	1.237MetArg: 1.237 ± 0.037	1.356MetSer: 1.356 ± 0.038	1.542MetThr: 1.542 ± 0.036	1.186MetVal: 1.186 ± 0.037	0.125MetTrp: 0.125 ± 0.012	0.217MetTyr: 0.217 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.272AsnAla: 2.272 ± 0.057	0.128AsnCys: 0.128 ± 0.012	1.051AsnAsp: 1.051 ± 0.037	0.93AsnGlu: 0.93 ± 0.036	0.525AsnPhe: 0.525 ± 0.029	1.87AsnGly: 1.87 ± 0.053	0.314AsnHis: 0.314 ± 0.019	0.727AsnIle: 0.727 ± 0.029	0.337AsnLys: 0.337 ± 0.019	1.742AsnLeu: 1.742 ± 0.05	0.253AsnMet: 0.253 ± 0.017	0.394AsnAsn: 0.394 ± 0.025	1.262AsnPro: 1.262 ± 0.042	0.489AsnGln: 0.489 ± 0.026	1.416AsnArg: 1.416 ± 0.036	0.934AsnSer: 0.934 ± 0.039	1.043AsnThr: 1.043 ± 0.038	1.529AsnVal: 1.529 ± 0.046	0.271AsnTrp: 0.271 ± 0.018	0.437AsnTyr: 0.437 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	7.321ProAla: 7.321 ± 0.113	0.223ProCys: 0.223 ± 0.016	3.668ProAsp: 3.668 ± 0.066	4.083ProGlu: 4.083 ± 0.081	1.669ProPhe: 1.669 ± 0.042	5.096ProGly: 5.096 ± 0.086	1.044ProHis: 1.044 ± 0.033	1.99ProIle: 1.99 ± 0.052	0.856ProLys: 0.856 ± 0.035	5.224ProLeu: 5.224 ± 0.078	0.793ProMet: 0.793 ± 0.033	0.952ProAsn: 0.952 ± 0.033	2.364ProPro: 2.364 ± 0.063	1.405ProGln: 1.405 ± 0.039	3.786ProArg: 3.786 ± 0.074	3.471ProSer: 3.471 ± 0.06	3.446ProThr: 3.446 ± 0.068	5.099ProVal: 5.099 ± 0.082	0.789ProTrp: 0.789 ± 0.032	0.956ProTyr: 0.956 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.267GlnAla: 3.267 ± 0.073	0.12GlnCys: 0.12 ± 0.011	1.182GlnAsp: 1.182 ± 0.037	1.473GlnGlu: 1.473 ± 0.035	0.736GlnPhe: 0.736 ± 0.027	2.03GlnGly: 2.03 ± 0.049	0.551GlnHis: 0.551 ± 0.027	1.262GlnIle: 1.262 ± 0.037	0.702GlnLys: 0.702 ± 0.029	3.033GlnLeu: 3.033 ± 0.06	0.394GlnMet: 0.394 ± 0.017	0.67GlnAsn: 0.67 ± 0.03	1.449GlnPro: 1.449 ± 0.041	1.037GlnGln: 1.037 ± 0.039	2.248GlnArg: 2.248 ± 0.049	1.503GlnSer: 1.503 ± 0.04	1.422GlnThr: 1.422 ± 0.045	2.199GlnVal: 2.199 ± 0.05	0.426GlnTrp: 0.426 ± 0.02	0.667GlnTyr: 0.667 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	9.636ArgAla: 9.636 ± 0.112	0.42ArgCys: 0.42 ± 0.022	4.216ArgAsp: 4.216 ± 0.074	4.616ArgGlu: 4.616 ± 0.075	2.585ArgPhe: 2.585 ± 0.052	5.833ArgGly: 5.833 ± 0.075	1.643ArgHis: 1.643 ± 0.046	3.762ArgIle: 3.762 ± 0.07	1.197ArgLys: 1.197 ± 0.041	8.249ArgLeu: 8.249 ± 0.119	1.62ArgMet: 1.62 ± 0.045	1.248ArgAsn: 1.248 ± 0.039	4.214ArgPro: 4.214 ± 0.083	1.88ArgGln: 1.88 ± 0.048	7.403ArgArg: 7.403 ± 0.114	5.194ArgSer: 5.194 ± 0.072	4.781ArgThr: 4.781 ± 0.077	6.299ArgVal: 6.299 ± 0.084	1.172ArgTrp: 1.172 ± 0.037	1.589ArgTyr: 1.589 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	8.595SerAla: 8.595 ± 0.122	0.318SerCys: 0.318 ± 0.019	3.514SerAsp: 3.514 ± 0.074	2.944SerGlu: 2.944 ± 0.063	2.005SerPhe: 2.005 ± 0.055	6.817SerGly: 6.817 ± 0.101	0.986SerHis: 0.986 ± 0.034	2.644SerIle: 2.644 ± 0.06	1.053SerLys: 1.053 ± 0.04	5.831SerLeu: 5.831 ± 0.072	1.119SerMet: 1.119 ± 0.034	1.083SerAsn: 1.083 ± 0.038	3.272SerPro: 3.272 ± 0.066	1.378SerGln: 1.378 ± 0.043	4.428SerArg: 4.428 ± 0.071	4.369SerSer: 4.369 ± 0.088	4.261SerThr: 4.261 ± 0.086	5.419SerVal: 5.419 ± 0.081	0.96SerTrp: 0.96 ± 0.03	1.303SerTyr: 1.303 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	8.504ThrAla: 8.504 ± 0.126	0.307ThrCys: 0.307 ± 0.019	3.298ThrAsp: 3.298 ± 0.065	3.029ThrGlu: 3.029 ± 0.058	1.713ThrPhe: 1.713 ± 0.044	6.152ThrGly: 6.152 ± 0.093	0.974ThrHis: 0.974 ± 0.032	2.564ThrIle: 2.564 ± 0.055	1.025ThrLys: 1.025 ± 0.036	6.247ThrLeu: 6.247 ± 0.091	0.834ThrMet: 0.834 ± 0.03	1.105ThrAsn: 1.105 ± 0.041	4.056ThrPro: 4.056 ± 0.058	1.305ThrGln: 1.305 ± 0.043	3.904ThrArg: 3.904 ± 0.067	3.883ThrSer: 3.883 ± 0.081	4.212ThrThr: 4.212 ± 0.091	6.024ThrVal: 6.024 ± 0.097	0.784ThrTrp: 0.784 ± 0.033	0.981ThrTyr: 0.981 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	11.919ValAla: 11.919 ± 0.127	0.534ValCys: 0.534 ± 0.026	5.934ValAsp: 5.934 ± 0.096	5.044ValGlu: 5.044 ± 0.082	2.741ValPhe: 2.741 ± 0.057	7.352ValGly: 7.352 ± 0.106	1.793ValHis: 1.793 ± 0.049	3.892ValIle: 3.892 ± 0.068	1.491ValLys: 1.491 ± 0.053	10.627ValLeu: 10.627 ± 0.142	1.211ValMet: 1.211 ± 0.04	1.643ValAsn: 1.643 ± 0.045	4.965ValPro: 4.965 ± 0.088	2.412ValGln: 2.412 ± 0.048	6.375ValArg: 6.375 ± 0.089	5.473ValSer: 5.473 ± 0.083	5.544ValThr: 5.544 ± 0.076	9.776ValVal: 9.776 ± 0.142	1.049ValTrp: 1.049 ± 0.039	1.605ValTyr: 1.605 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	1.505TrpAla: 1.505 ± 0.046	0.085TrpCys: 0.085 ± 0.011	0.708TrpAsp: 0.708 ± 0.031	0.659TrpGlu: 0.659 ± 0.024	0.501TrpPhe: 0.501 ± 0.025	0.945TrpGly: 0.945 ± 0.036	0.278TrpHis: 0.278 ± 0.016	0.665TrpIle: 0.665 ± 0.032	0.324TrpLys: 0.324 ± 0.022	1.56TrpLeu: 1.56 ± 0.047	0.295TrpMet: 0.295 ± 0.02	0.385TrpAsn: 0.385 ± 0.022	0.69TrpPro: 0.69 ± 0.025	0.485TrpGln: 0.485 ± 0.022	1.2TrpArg: 1.2 ± 0.039	1.03TrpSer: 1.03 ± 0.036	0.898TrpThr: 0.898 ± 0.041	0.987TrpVal: 0.987 ± 0.033	0.283TrpTrp: 0.283 ± 0.019	0.257TrpTyr: 0.257 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.166TyrAla: 2.166 ± 0.058	0.124TyrCys: 0.124 ± 0.012	1.32TyrAsp: 1.32 ± 0.051	1.023TyrGlu: 1.023 ± 0.034	0.628TyrPhe: 0.628 ± 0.026	1.875TyrGly: 1.875 ± 0.044	0.298TyrHis: 0.298 ± 0.016	0.607TyrIle: 0.607 ± 0.03	0.326TyrLys: 0.326 ± 0.025	2.121TyrLeu: 2.121 ± 0.054	0.227TyrMet: 0.227 ± 0.015	0.435TyrAsn: 0.435 ± 0.025	0.972TyrPro: 0.972 ± 0.03	0.555TyrGln: 0.555 ± 0.028	1.711TyrArg: 1.711 ± 0.045	1.309TyrSer: 1.309 ± 0.042	1.068TyrThr: 1.068 ± 0.042	1.474TyrVal: 1.474 ± 0.039	0.281TyrTrp: 0.281 ± 0.016	0.509TyrTyr: 0.509 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2806 proteins (922148 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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