Amino acid dipepetide frequency for Bauldia litoralis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.22AlaAla: 18.22 ± 0.17	0.971AlaCys: 0.971 ± 0.025	7.815AlaAsp: 7.815 ± 0.075	8.153AlaGlu: 8.153 ± 0.084	4.767AlaPhe: 4.767 ± 0.058	11.754AlaGly: 11.754 ± 0.102	1.993AlaHis: 1.993 ± 0.037	7.374AlaIle: 7.374 ± 0.08	3.465AlaLys: 3.465 ± 0.06	12.56AlaLeu: 12.56 ± 0.103	3.546AlaMet: 3.546 ± 0.045	2.941AlaAsn: 2.941 ± 0.046	5.598AlaPro: 5.598 ± 0.073	2.899AlaGln: 2.899 ± 0.048	8.645AlaArg: 8.645 ± 0.094	6.284AlaSer: 6.284 ± 0.072	6.794AlaThr: 6.794 ± 0.078	9.649AlaVal: 9.649 ± 0.106	1.512AlaTrp: 1.512 ± 0.033	2.581AlaTyr: 2.581 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.813CysAla: 0.813 ± 0.026	0.093CysCys: 0.093 ± 0.008	0.505CysAsp: 0.505 ± 0.02	0.391CysGlu: 0.391 ± 0.018	0.312CysPhe: 0.312 ± 0.015	0.837CysGly: 0.837 ± 0.026	0.238CysHis: 0.238 ± 0.013	0.347CysIle: 0.347 ± 0.016	0.156CysLys: 0.156 ± 0.011	0.745CysLeu: 0.745 ± 0.023	0.137CysMet: 0.137 ± 0.009	0.173CysAsn: 0.173 ± 0.011	0.413CysPro: 0.413 ± 0.017	0.183CysGln: 0.183 ± 0.011	0.566CysArg: 0.566 ± 0.021	0.4CysSer: 0.4 ± 0.015	0.358CysThr: 0.358 ± 0.015	0.572CysVal: 0.572 ± 0.023	0.102CysTrp: 0.102 ± 0.009	0.182CysTyr: 0.182 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.543AspAla: 7.543 ± 0.078	0.481AspCys: 0.481 ± 0.018	4.082AspAsp: 4.082 ± 0.064	3.73AspGlu: 3.73 ± 0.059	2.522AspPhe: 2.522 ± 0.041	6.155AspGly: 6.155 ± 0.086	1.35AspHis: 1.35 ± 0.035	3.486AspIle: 3.486 ± 0.049	1.782AspLys: 1.782 ± 0.039	6.452AspLeu: 6.452 ± 0.07	1.33AspMet: 1.33 ± 0.028	1.405AspAsn: 1.405 ± 0.032	3.819AspPro: 3.819 ± 0.055	1.669AspGln: 1.669 ± 0.039	4.977AspArg: 4.977 ± 0.06	2.381AspSer: 2.381 ± 0.037	3.034AspThr: 3.034 ± 0.074	4.381AspVal: 4.381 ± 0.062	1.084AspTrp: 1.084 ± 0.028	1.647AspTyr: 1.647 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	8.23GluAla: 8.23 ± 0.087	0.312GluCys: 0.312 ± 0.016	2.985GluAsp: 2.985 ± 0.042	3.19GluGlu: 3.19 ± 0.055	1.674GluPhe: 1.674 ± 0.034	4.392GluGly: 4.392 ± 0.057	1.053GluHis: 1.053 ± 0.028	3.553GluIle: 3.553 ± 0.049	2.005GluLys: 2.005 ± 0.038	4.713GluLeu: 4.713 ± 0.058	1.503GluMet: 1.503 ± 0.033	1.456GluAsn: 1.456 ± 0.035	3.07GluPro: 3.07 ± 0.058	1.68GluGln: 1.68 ± 0.034	4.655GluArg: 4.655 ± 0.062	2.54GluSer: 2.54 ± 0.04	3.965GluThr: 3.965 ± 0.047	4.042GluVal: 4.042 ± 0.048	0.709GluTrp: 0.709 ± 0.018	0.941GluTyr: 0.941 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.88PheAla: 4.88 ± 0.054	0.34PheCys: 0.34 ± 0.014	2.958PheAsp: 2.958 ± 0.046	2.103PheGlu: 2.103 ± 0.045	1.578PhePhe: 1.578 ± 0.034	3.985PheGly: 3.985 ± 0.051	0.749PheHis: 0.749 ± 0.027	1.79PheIle: 1.79 ± 0.036	0.91PheLys: 0.91 ± 0.027	3.481PheLeu: 3.481 ± 0.059	0.719PheMet: 0.719 ± 0.026	1.028PheAsn: 1.028 ± 0.027	1.708PhePro: 1.708 ± 0.037	0.974PheGln: 0.974 ± 0.024	2.318PheArg: 2.318 ± 0.047	2.051PheSer: 2.051 ± 0.034	2.002PheThr: 2.002 ± 0.04	3.234PheVal: 3.234 ± 0.049	0.549PheTrp: 0.549 ± 0.02	0.891PheTyr: 0.891 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.916GlyAla: 9.916 ± 0.102	0.753GlyCys: 0.753 ± 0.025	5.4GlyAsp: 5.4 ± 0.079	5.128GlyGlu: 5.128 ± 0.069	3.778GlyPhe: 3.778 ± 0.052	8.409GlyGly: 8.409 ± 0.118	1.905GlyHis: 1.905 ± 0.037	5.169GlyIle: 5.169 ± 0.06	3.337GlyLys: 3.337 ± 0.05	8.855GlyLeu: 8.855 ± 0.082	2.403GlyMet: 2.403 ± 0.037	2.37GlyAsn: 2.37 ± 0.048	3.853GlyPro: 3.853 ± 0.053	2.51GlyGln: 2.51 ± 0.043	6.389GlyArg: 6.389 ± 0.069	4.772GlySer: 4.772 ± 0.067	4.852GlyThr: 4.852 ± 0.067	6.723GlyVal: 6.723 ± 0.067	1.38GlyTrp: 1.38 ± 0.03	2.386GlyTyr: 2.386 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.16HisAla: 2.16 ± 0.037	0.227HisCys: 0.227 ± 0.012	1.233HisAsp: 1.233 ± 0.027	0.939HisGlu: 0.939 ± 0.025	0.843HisPhe: 0.843 ± 0.023	1.847HisGly: 1.847 ± 0.04	0.555HisHis: 0.555 ± 0.025	0.927HisIle: 0.927 ± 0.024	0.423HisLys: 0.423 ± 0.016	1.932HisLeu: 1.932 ± 0.037	0.419HisMet: 0.419 ± 0.017	0.439HisAsn: 0.439 ± 0.018	1.264HisPro: 1.264 ± 0.029	0.494HisGln: 0.494 ± 0.018	1.386HisArg: 1.386 ± 0.034	0.822HisSer: 0.822 ± 0.027	0.767HisThr: 0.767 ± 0.02	1.443HisVal: 1.443 ± 0.032	0.296HisTrp: 0.296 ± 0.015	0.473HisTyr: 0.473 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	7.989IleAla: 7.989 ± 0.075	0.447IleCys: 0.447 ± 0.017	4.217IleAsp: 4.217 ± 0.057	3.587IleGlu: 3.587 ± 0.054	1.832IlePhe: 1.832 ± 0.037	5.669IleGly: 5.669 ± 0.062	0.967IleHis: 0.967 ± 0.026	2.39IleIle: 2.39 ± 0.054	1.355IleLys: 1.355 ± 0.029	4.777IleLeu: 4.777 ± 0.066	0.923IleMet: 0.923 ± 0.026	1.443IleAsn: 1.443 ± 0.031	2.49IlePro: 2.49 ± 0.042	1.145IleGln: 1.145 ± 0.025	3.422IleArg: 3.422 ± 0.044	2.631IleSer: 2.631 ± 0.043	2.637IleThr: 2.637 ± 0.041	5.138IleVal: 5.138 ± 0.059	0.612IleTrp: 0.612 ± 0.019	1.214IleTyr: 1.214 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.893LysAla: 3.893 ± 0.059	0.143LysCys: 0.143 ± 0.009	1.593LysAsp: 1.593 ± 0.039	1.357LysGlu: 1.357 ± 0.038	0.749LysPhe: 0.749 ± 0.024	2.444LysGly: 2.444 ± 0.048	0.507LysHis: 0.507 ± 0.019	1.552LysIle: 1.552 ± 0.038	1.042LysLys: 1.042 ± 0.033	2.812LysLeu: 2.812 ± 0.042	0.641LysMet: 0.641 ± 0.019	0.753LysAsn: 0.753 ± 0.024	1.966LysPro: 1.966 ± 0.044	0.797LysGln: 0.797 ± 0.023	2.151LysArg: 2.151 ± 0.038	1.623LysSer: 1.623 ± 0.031	1.841LysThr: 1.841 ± 0.04	2.287LysVal: 2.287 ± 0.043	0.352LysTrp: 0.352 ± 0.014	0.556LysTyr: 0.556 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	13.742LeuAla: 13.742 ± 0.117	0.748LeuCys: 0.748 ± 0.021	6.398LeuAsp: 6.398 ± 0.072	4.767LeuGlu: 4.767 ± 0.055	3.618LeuPhe: 3.618 ± 0.051	8.486LeuGly: 8.486 ± 0.081	1.625LeuHis: 1.625 ± 0.03	5.126LeuIle: 5.126 ± 0.061	3.077LeuLys: 3.077 ± 0.052	8.586LeuLeu: 8.586 ± 0.095	2.169LeuMet: 2.169 ± 0.041	2.289LeuAsn: 2.289 ± 0.039	5.161LeuPro: 5.161 ± 0.061	2.167LeuGln: 2.167 ± 0.04	6.151LeuArg: 6.151 ± 0.078	5.868LeuSer: 5.868 ± 0.058	5.518LeuThr: 5.518 ± 0.061	7.713LeuVal: 7.713 ± 0.078	1.064LeuTrp: 1.064 ± 0.029	1.957LeuTyr: 1.957 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.23MetAla: 3.23 ± 0.045	0.113MetCys: 0.113 ± 0.01	1.079MetAsp: 1.079 ± 0.024	1.084MetGlu: 1.084 ± 0.026	0.671MetPhe: 0.671 ± 0.02	1.604MetGly: 1.604 ± 0.038	0.373MetHis: 0.373 ± 0.016	1.42MetIle: 1.42 ± 0.035	0.882MetLys: 0.882 ± 0.022	2.271MetLeu: 2.271 ± 0.045	0.625MetMet: 0.625 ± 0.026	0.708MetAsn: 0.708 ± 0.021	1.465MetPro: 1.465 ± 0.031	0.694MetGln: 0.694 ± 0.021	1.727MetArg: 1.727 ± 0.036	1.548MetSer: 1.548 ± 0.029	1.955MetThr: 1.955 ± 0.032	1.876MetVal: 1.876 ± 0.037	0.208MetTrp: 0.208 ± 0.011	0.315MetTyr: 0.315 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.089AsnAla: 3.089 ± 0.044	0.219AsnCys: 0.219 ± 0.013	1.51AsnAsp: 1.51 ± 0.043	1.156AsnGlu: 1.156 ± 0.028	0.933AsnPhe: 0.933 ± 0.026	2.438AsnGly: 2.438 ± 0.048	0.465AsnHis: 0.465 ± 0.02	1.296AsnIle: 1.296 ± 0.03	0.585AsnLys: 0.585 ± 0.02	2.386AsnLeu: 2.386 ± 0.045	0.531AsnMet: 0.531 ± 0.019	0.662AsnAsn: 0.662 ± 0.022	1.781AsnPro: 1.781 ± 0.032	0.721AsnGln: 0.721 ± 0.023	1.79AsnArg: 1.79 ± 0.035	1.124AsnSer: 1.124 ± 0.025	1.231AsnThr: 1.231 ± 0.032	1.928AsnVal: 1.928 ± 0.044	0.425AsnTrp: 0.425 ± 0.016	0.646AsnTyr: 0.646 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.466ProAla: 6.466 ± 0.075	0.273ProCys: 0.273 ± 0.013	4.182ProAsp: 4.182 ± 0.057	3.871ProGlu: 3.871 ± 0.053	2.03ProPhe: 2.03 ± 0.039	4.751ProGly: 4.751 ± 0.053	0.967ProHis: 0.967 ± 0.021	2.578ProIle: 2.578 ± 0.041	1.498ProLys: 1.498 ± 0.034	4.506ProLeu: 4.506 ± 0.057	1.167ProMet: 1.167 ± 0.031	1.288ProAsn: 1.288 ± 0.032	2.965ProPro: 2.965 ± 0.068	1.304ProGln: 1.304 ± 0.027	2.891ProArg: 2.891 ± 0.047	2.714ProSer: 2.714 ± 0.047	2.806ProThr: 2.806 ± 0.044	4.456ProVal: 4.456 ± 0.06	0.71ProTrp: 0.71 ± 0.02	1.157ProTyr: 1.157 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	3.394GlnAla: 3.394 ± 0.055	0.173GlnCys: 0.173 ± 0.01	1.296GlnAsp: 1.296 ± 0.028	1.198GlnGlu: 1.198 ± 0.029	0.959GlnPhe: 0.959 ± 0.031	1.955GlnGly: 1.955 ± 0.04	0.456GlnHis: 0.456 ± 0.018	1.567GlnIle: 1.567 ± 0.034	0.865GlnLys: 0.865 ± 0.025	2.314GlnLeu: 2.314 ± 0.037	0.727GlnMet: 0.727 ± 0.022	0.644GlnAsn: 0.644 ± 0.024	1.57GlnPro: 1.57 ± 0.032	0.877GlnGln: 0.877 ± 0.028	2.002GlnArg: 2.002 ± 0.042	1.508GlnSer: 1.508 ± 0.028	1.46GlnThr: 1.46 ± 0.03	1.97GlnVal: 1.97 ± 0.039	0.366GlnTrp: 0.366 ± 0.016	0.509GlnTyr: 0.509 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	7.524ArgAla: 7.524 ± 0.092	0.484ArgCys: 0.484 ± 0.02	4.392ArgAsp: 4.392 ± 0.064	3.855ArgGlu: 3.855 ± 0.052	2.986ArgPhe: 2.986 ± 0.055	4.955ArgGly: 4.955 ± 0.066	1.586ArgHis: 1.586 ± 0.028	4.104ArgIle: 4.104 ± 0.056	2.073ArgLys: 2.073 ± 0.04	7.706ArgLeu: 7.706 ± 0.093	1.868ArgMet: 1.868 ± 0.036	1.726ArgAsn: 1.726 ± 0.03	3.672ArgPro: 3.672 ± 0.048	2.318ArgGln: 2.318 ± 0.044	5.699ArgArg: 5.699 ± 0.081	3.723ArgSer: 3.723 ± 0.053	3.457ArgThr: 3.457 ± 0.047	4.735ArgVal: 4.735 ± 0.059	0.971ArgTrp: 0.971 ± 0.025	1.681ArgTyr: 1.681 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	5.767SerAla: 5.767 ± 0.071	0.364SerCys: 0.364 ± 0.017	3.207SerAsp: 3.207 ± 0.046	2.831SerGlu: 2.831 ± 0.042	2.234SerPhe: 2.234 ± 0.038	5.512SerGly: 5.512 ± 0.08	0.993SerHis: 0.993 ± 0.023	2.835SerIle: 2.835 ± 0.05	1.384SerLys: 1.384 ± 0.034	5.249SerLeu: 5.249 ± 0.055	1.228SerMet: 1.228 ± 0.026	1.231SerAsn: 1.231 ± 0.031	2.835SerPro: 2.835 ± 0.041	1.351SerGln: 1.351 ± 0.028	3.475SerArg: 3.475 ± 0.046	2.665SerSer: 2.665 ± 0.046	2.573SerThr: 2.573 ± 0.039	4.161SerVal: 4.161 ± 0.05	0.676SerTrp: 0.676 ± 0.02	1.191SerTyr: 1.191 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.467ThrAla: 6.467 ± 0.064	0.411ThrCys: 0.411 ± 0.018	3.103ThrAsp: 3.103 ± 0.052	2.798ThrGlu: 2.798 ± 0.045	2.199ThrPhe: 2.199 ± 0.039	5.583ThrGly: 5.583 ± 0.07	0.964ThrHis: 0.964 ± 0.026	3.312ThrIle: 3.312 ± 0.054	1.267ThrLys: 1.267 ± 0.029	5.706ThrLeu: 5.706 ± 0.068	1.33ThrMet: 1.33 ± 0.03	1.298ThrAsn: 1.298 ± 0.032	3.293ThrPro: 3.293 ± 0.049	1.161ThrGln: 1.161 ± 0.027	3.413ThrArg: 3.413 ± 0.047	2.675ThrSer: 2.675 ± 0.04	3.078ThrThr: 3.078 ± 0.047	4.904ThrVal: 4.904 ± 0.06	0.684ThrTrp: 0.684 ± 0.023	1.258ThrTyr: 1.258 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	10.511ValAla: 10.511 ± 0.093	0.622ValCys: 0.622 ± 0.021	5.049ValAsp: 5.049 ± 0.061	4.794ValGlu: 4.794 ± 0.053	3.072ValPhe: 3.072 ± 0.046	6.476ValGly: 6.476 ± 0.075	1.391ValHis: 1.391 ± 0.036	4.454ValIle: 4.454 ± 0.054	2.041ValLys: 2.041 ± 0.042	7.342ValLeu: 7.342 ± 0.077	1.829ValMet: 1.829 ± 0.031	2.036ValAsn: 2.036 ± 0.039	3.802ValPro: 3.802 ± 0.051	1.653ValGln: 1.653 ± 0.031	4.874ValArg: 4.874 ± 0.059	4.466ValSer: 4.466 ± 0.054	4.726ValThr: 4.726 ± 0.061	6.937ValVal: 6.937 ± 0.076	0.947ValTrp: 0.947 ± 0.026	1.636ValTyr: 1.636 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.186TrpAla: 1.186 ± 0.032	0.127TrpCys: 0.127 ± 0.01	0.721TrpAsp: 0.721 ± 0.022	0.557TrpGlu: 0.557 ± 0.017	0.557TrpPhe: 0.557 ± 0.021	0.9TrpGly: 0.9 ± 0.024	0.312TrpHis: 0.312 ± 0.016	0.728TrpIle: 0.728 ± 0.024	0.387TrpLys: 0.387 ± 0.016	1.526TrpLeu: 1.526 ± 0.039	0.369TrpMet: 0.369 ± 0.015	0.42TrpAsn: 0.42 ± 0.018	0.699TrpPro: 0.699 ± 0.021	0.574TrpGln: 0.574 ± 0.018	1.168TrpArg: 1.168 ± 0.028	0.862TrpSer: 0.862 ± 0.026	0.807TrpThr: 0.807 ± 0.026	0.825TrpVal: 0.825 ± 0.025	0.238TrpTrp: 0.238 ± 0.014	0.302TrpTyr: 0.302 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.5TyrAla: 2.5 ± 0.043	0.221TyrCys: 0.221 ± 0.014	1.589TyrAsp: 1.589 ± 0.036	1.179TyrGlu: 1.179 ± 0.03	0.937TyrPhe: 0.937 ± 0.026	2.134TyrGly: 2.134 ± 0.04	0.441TyrHis: 0.441 ± 0.02	0.878TyrIle: 0.878 ± 0.026	0.526TyrLys: 0.526 ± 0.022	2.312TyrLeu: 2.312 ± 0.04	0.385TyrMet: 0.385 ± 0.015	0.604TyrAsn: 0.604 ± 0.022	1.154TyrPro: 1.154 ± 0.029	0.637TyrGln: 0.637 ± 0.022	1.813TyrArg: 1.813 ± 0.035	1.105TyrSer: 1.105 ± 0.031	1.042TyrThr: 1.042 ± 0.025	1.685TyrVal: 1.685 ± 0.032	0.382TyrTrp: 0.382 ± 0.017	0.597TyrTyr: 0.597 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4760 proteins (1523614 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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