Amino acid dipepetide frequency for Ophiocordyceps camponoti-saundersi (nom. inval.)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.354AlaAla: 11.354 ± 0.084	1.192AlaCys: 1.192 ± 0.02	5.231AlaAsp: 5.231 ± 0.036	5.565AlaGlu: 5.565 ± 0.057	3.108AlaPhe: 3.108 ± 0.033	6.297AlaGly: 6.297 ± 0.05	1.874AlaHis: 1.874 ± 0.022	3.903AlaIle: 3.903 ± 0.034	4.148AlaLys: 4.148 ± 0.044	8.186AlaLeu: 8.186 ± 0.058	2.226AlaMet: 2.226 ± 0.027	2.759AlaAsn: 2.759 ± 0.03	4.918AlaPro: 4.918 ± 0.045	3.437AlaGln: 3.437 ± 0.032	5.968AlaArg: 5.968 ± 0.044	8.172AlaSer: 8.172 ± 0.05	5.329AlaThr: 5.329 ± 0.044	6.395AlaVal: 6.395 ± 0.046	1.199AlaTrp: 1.199 ± 0.019	2.03AlaTyr: 2.03 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	1.031CysAla: 1.031 ± 0.019	0.269CysCys: 0.269 ± 0.01	0.729CysAsp: 0.729 ± 0.014	0.651CysGlu: 0.651 ± 0.015	0.563CysPhe: 0.563 ± 0.012	1.01CysGly: 1.01 ± 0.02	0.387CysHis: 0.387 ± 0.012	0.632CysIle: 0.632 ± 0.014	0.506CysLys: 0.506 ± 0.012	1.403CysLeu: 1.403 ± 0.022	0.262CysMet: 0.262 ± 0.008	0.414CysAsn: 0.414 ± 0.011	0.748CysPro: 0.748 ± 0.02	0.478CysGln: 0.478 ± 0.013	0.971CysArg: 0.971 ± 0.016	0.974CysSer: 0.974 ± 0.019	0.607CysThr: 0.607 ± 0.011	0.862CysVal: 0.862 ± 0.017	0.195CysTrp: 0.195 ± 0.008	0.344CysTyr: 0.344 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	5.677AspAla: 5.677 ± 0.047	0.725AspCys: 0.725 ± 0.016	6.183AspAsp: 6.183 ± 0.071	5.191AspGlu: 5.191 ± 0.048	2.239AspPhe: 2.239 ± 0.025	5.002AspGly: 5.002 ± 0.05	1.26AspHis: 1.26 ± 0.019	2.547AspIle: 2.547 ± 0.032	2.625AspLys: 2.625 ± 0.036	5.07AspLeu: 5.07 ± 0.036	1.486AspMet: 1.486 ± 0.02	1.782AspAsn: 1.782 ± 0.022	3.063AspPro: 3.063 ± 0.025	1.902AspGln: 1.902 ± 0.025	3.575AspArg: 3.575 ± 0.036	4.234AspSer: 4.234 ± 0.043	2.579AspThr: 2.579 ± 0.031	4.303AspVal: 4.303 ± 0.031	0.902AspTrp: 0.902 ± 0.017	1.506AspTyr: 1.506 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	6.428GluAla: 6.428 ± 0.053	0.642GluCys: 0.642 ± 0.014	4.083GluAsp: 4.083 ± 0.045	5.087GluGlu: 5.087 ± 0.074	1.707GluPhe: 1.707 ± 0.021	3.501GluGly: 3.501 ± 0.041	1.248GluHis: 1.248 ± 0.017	2.333GluIle: 2.333 ± 0.031	3.312GluLys: 3.312 ± 0.046	5.184GluLeu: 5.184 ± 0.046	1.521GluMet: 1.521 ± 0.021	1.849GluAsn: 1.849 ± 0.022	2.977GluPro: 2.977 ± 0.033	2.355GluGln: 2.355 ± 0.03	4.129GluArg: 4.129 ± 0.043	4.185GluSer: 4.185 ± 0.041	3.422GluThr: 3.422 ± 0.036	3.4GluVal: 3.4 ± 0.033	0.797GluTrp: 0.797 ± 0.014	1.385GluTyr: 1.385 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.013PheAla: 3.013 ± 0.033	0.572PheCys: 0.572 ± 0.015	2.277PheAsp: 2.277 ± 0.027	1.95PheGlu: 1.95 ± 0.026	1.546PhePhe: 1.546 ± 0.023	2.651PheGly: 2.651 ± 0.034	0.886PheHis: 0.886 ± 0.015	1.536PheIle: 1.536 ± 0.021	1.32PheLys: 1.32 ± 0.02	3.294PheLeu: 3.294 ± 0.034	0.71PheMet: 0.71 ± 0.013	1.236PheAsn: 1.236 ± 0.019	1.819PhePro: 1.819 ± 0.024	1.247PheGln: 1.247 ± 0.02	2.2PheArg: 2.2 ± 0.025	2.784PheSer: 2.784 ± 0.031	1.807PheThr: 1.807 ± 0.025	2.454PheVal: 2.454 ± 0.025	0.57PheTrp: 0.57 ± 0.012	0.976PheTyr: 0.976 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.391GlyAla: 5.391 ± 0.046	0.933GlyCys: 0.933 ± 0.017	3.998GlyAsp: 3.998 ± 0.039	3.666GlyGlu: 3.666 ± 0.036	2.702GlyPhe: 2.702 ± 0.028	6.782GlyGly: 6.782 ± 0.089	1.793GlyHis: 1.793 ± 0.027	3.093GlyIle: 3.093 ± 0.031	3.279GlyLys: 3.279 ± 0.04	6.224GlyLeu: 6.224 ± 0.052	1.514GlyMet: 1.514 ± 0.022	2.351GlyAsn: 2.351 ± 0.041	3.641GlyPro: 3.641 ± 0.078	2.652GlyGln: 2.652 ± 0.033	5.019GlyArg: 5.019 ± 0.04	6.023GlySer: 6.023 ± 0.045	3.518GlyThr: 3.518 ± 0.044	4.222GlyVal: 4.222 ± 0.038	1.129GlyTrp: 1.129 ± 0.021	1.914GlyTyr: 1.914 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	1.894HisAla: 1.894 ± 0.021	0.348HisCys: 0.348 ± 0.011	1.507HisAsp: 1.507 ± 0.022	1.309HisGlu: 1.309 ± 0.02	0.856HisPhe: 0.856 ± 0.015	1.82HisGly: 1.82 ± 0.029	1.189HisHis: 1.189 ± 0.035	0.976HisIle: 0.976 ± 0.016	0.84HisLys: 0.84 ± 0.017	2.338HisLeu: 2.338 ± 0.026	0.512HisMet: 0.512 ± 0.012	0.738HisAsn: 0.738 ± 0.014	1.617HisPro: 1.617 ± 0.024	1.13HisGln: 1.13 ± 0.023	1.764HisArg: 1.764 ± 0.023	1.655HisSer: 1.655 ± 0.022	1.023HisThr: 1.023 ± 0.017	1.648HisVal: 1.648 ± 0.023	0.316HisTrp: 0.316 ± 0.009	0.643HisTyr: 0.643 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.463IleAla: 3.463 ± 0.035	0.685IleCys: 0.685 ± 0.016	2.625IleAsp: 2.625 ± 0.027	2.344IleGlu: 2.344 ± 0.023	1.687IlePhe: 1.687 ± 0.024	2.721IleGly: 2.721 ± 0.031	1.032IleHis: 1.032 ± 0.017	1.973IleIle: 1.973 ± 0.025	1.921IleLys: 1.921 ± 0.028	3.828IleLeu: 3.828 ± 0.038	0.923IleMet: 0.923 ± 0.017	1.503IleAsn: 1.503 ± 0.02	2.406IlePro: 2.406 ± 0.024	1.504IleGln: 1.504 ± 0.02	2.816IleArg: 2.816 ± 0.027	3.146IleSer: 3.146 ± 0.033	2.089IleThr: 2.089 ± 0.023	2.939IleVal: 2.939 ± 0.027	0.581IleTrp: 0.581 ± 0.012	1.11IleTyr: 1.11 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.404LysAla: 4.404 ± 0.043	0.496LysCys: 0.496 ± 0.014	2.605LysAsp: 2.605 ± 0.035	2.859LysGlu: 2.859 ± 0.035	1.273LysPhe: 1.273 ± 0.018	2.716LysGly: 2.716 ± 0.033	1.002LysHis: 1.002 ± 0.019	1.776LysIle: 1.776 ± 0.024	3.067LysLys: 3.067 ± 0.054	3.985LysLeu: 3.985 ± 0.034	1.075LysMet: 1.075 ± 0.017	1.414LysAsn: 1.414 ± 0.023	2.772LysPro: 2.772 ± 0.04	1.774LysGln: 1.774 ± 0.025	3.496LysArg: 3.496 ± 0.04	3.22LysSer: 3.22 ± 0.035	2.862LysThr: 2.862 ± 0.03	2.572LysVal: 2.572 ± 0.028	0.557LysTrp: 0.557 ± 0.012	1.053LysTyr: 1.053 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.751LeuAla: 8.751 ± 0.058	1.299LeuCys: 1.299 ± 0.021	5.553LeuAsp: 5.553 ± 0.045	5.268LeuGlu: 5.268 ± 0.05	3.209LeuPhe: 3.209 ± 0.033	6.0LeuGly: 6.0 ± 0.044	2.234LeuHis: 2.234 ± 0.024	3.506LeuIle: 3.506 ± 0.034	3.741LeuLys: 3.741 ± 0.037	8.957LeuLeu: 8.957 ± 0.072	1.868LeuMet: 1.868 ± 0.022	2.762LeuAsn: 2.762 ± 0.028	5.609LeuPro: 5.609 ± 0.041	3.693LeuGln: 3.693 ± 0.033	6.771LeuArg: 6.771 ± 0.054	7.511LeuSer: 7.511 ± 0.05	4.751LeuThr: 4.751 ± 0.041	6.078LeuVal: 6.078 ± 0.046	1.216LeuTrp: 1.216 ± 0.02	2.247LeuTyr: 2.247 ± 0.03	0.0LeuXaa: 0.0 ± 0.0
Met	2.587MetAla: 2.587 ± 0.024	0.243MetCys: 0.243 ± 0.008	1.31MetAsp: 1.31 ± 0.02	1.299MetGlu: 1.299 ± 0.017	0.66MetPhe: 0.66 ± 0.011	1.44MetGly: 1.44 ± 0.02	0.466MetHis: 0.466 ± 0.011	0.818MetIle: 0.818 ± 0.016	0.929MetLys: 0.929 ± 0.017	2.044MetLeu: 2.044 ± 0.025	0.653MetMet: 0.653 ± 0.014	0.694MetAsn: 0.694 ± 0.013	1.432MetPro: 1.432 ± 0.019	0.843MetGln: 0.843 ± 0.016	1.499MetArg: 1.499 ± 0.02	1.834MetSer: 1.834 ± 0.024	1.515MetThr: 1.515 ± 0.019	1.354MetVal: 1.354 ± 0.016	0.239MetTrp: 0.239 ± 0.008	0.464MetTyr: 0.464 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.735AsnAla: 2.735 ± 0.029	0.41AsnCys: 0.41 ± 0.011	1.865AsnAsp: 1.865 ± 0.023	1.675AsnGlu: 1.675 ± 0.021	1.181AsnPhe: 1.181 ± 0.016	2.6AsnGly: 2.6 ± 0.046	0.798AsnHis: 0.798 ± 0.016	1.506AsnIle: 1.506 ± 0.02	1.475AsnLys: 1.475 ± 0.023	2.921AsnLeu: 2.921 ± 0.027	0.777AsnMet: 0.777 ± 0.012	1.273AsnAsn: 1.273 ± 0.027	2.024AsnPro: 2.024 ± 0.027	1.149AsnGln: 1.149 ± 0.018	1.975AsnArg: 1.975 ± 0.021	2.378AsnSer: 2.378 ± 0.029	1.579AsnThr: 1.579 ± 0.019	2.126AsnVal: 2.126 ± 0.023	0.474AsnTrp: 0.474 ± 0.012	0.873AsnTyr: 0.873 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.586ProAla: 5.586 ± 0.05	0.636ProCys: 0.636 ± 0.015	3.56ProAsp: 3.56 ± 0.036	3.5ProGlu: 3.5 ± 0.034	1.942ProPhe: 1.942 ± 0.028	4.024ProGly: 4.024 ± 0.07	1.314ProHis: 1.314 ± 0.021	2.115ProIle: 2.115 ± 0.026	2.349ProLys: 2.349 ± 0.027	5.021ProLeu: 5.021 ± 0.044	1.118ProMet: 1.118 ± 0.019	1.794ProAsn: 1.794 ± 0.025	6.218ProPro: 6.218 ± 0.111	2.471ProGln: 2.471 ± 0.036	4.024ProArg: 4.024 ± 0.038	6.29ProSer: 6.29 ± 0.061	3.646ProThr: 3.646 ± 0.04	3.787ProVal: 3.787 ± 0.034	0.758ProTrp: 0.758 ± 0.015	1.378ProTyr: 1.378 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.648GlnAla: 3.648 ± 0.035	0.422GlnCys: 0.422 ± 0.01	2.076GlnAsp: 2.076 ± 0.026	2.154GlnGlu: 2.154 ± 0.026	1.121GlnPhe: 1.121 ± 0.018	2.459GlnGly: 2.459 ± 0.026	1.16GlnHis: 1.16 ± 0.021	1.506GlnIle: 1.506 ± 0.022	1.72GlnLys: 1.72 ± 0.024	3.661GlnLeu: 3.661 ± 0.036	0.894GlnMet: 0.894 ± 0.017	1.21GlnAsn: 1.21 ± 0.024	2.69GlnPro: 2.69 ± 0.035	3.183GlnGln: 3.183 ± 0.09	2.967GlnArg: 2.967 ± 0.032	2.898GlnSer: 2.898 ± 0.03	2.165GlnThr: 2.165 ± 0.023	2.256GlnVal: 2.256 ± 0.028	0.511GlnTrp: 0.511 ± 0.011	0.945GlnTyr: 0.945 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	5.614ArgAla: 5.614 ± 0.046	0.944ArgCys: 0.944 ± 0.019	4.162ArgAsp: 4.162 ± 0.04	4.109ArgGlu: 4.109 ± 0.045	2.412ArgPhe: 2.412 ± 0.024	4.377ArgGly: 4.377 ± 0.042	1.989ArgHis: 1.989 ± 0.028	2.879ArgIle: 2.879 ± 0.031	3.493ArgLys: 3.493 ± 0.038	6.866ArgLeu: 6.866 ± 0.053	1.416ArgMet: 1.416 ± 0.021	2.269ArgAsn: 2.269 ± 0.023	4.33ArgPro: 4.33 ± 0.041	3.133ArgGln: 3.133 ± 0.031	7.016ArgArg: 7.016 ± 0.061	5.378ArgSer: 5.378 ± 0.049	3.352ArgThr: 3.352 ± 0.031	3.835ArgVal: 3.835 ± 0.031	1.046ArgTrp: 1.046 ± 0.018	1.695ArgTyr: 1.695 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	7.115SerAla: 7.115 ± 0.049	0.988SerCys: 0.988 ± 0.018	4.432SerAsp: 4.432 ± 0.041	3.928SerGlu: 3.928 ± 0.035	2.898SerPhe: 2.898 ± 0.028	5.555SerGly: 5.555 ± 0.048	1.933SerHis: 1.933 ± 0.025	3.358SerIle: 3.358 ± 0.034	3.435SerLys: 3.435 ± 0.031	7.621SerLeu: 7.621 ± 0.051	1.741SerMet: 1.741 ± 0.022	2.555SerAsn: 2.555 ± 0.029	5.866SerPro: 5.866 ± 0.063	3.123SerGln: 3.123 ± 0.035	5.89SerArg: 5.89 ± 0.046	9.961SerSer: 9.961 ± 0.085	4.98SerThr: 4.98 ± 0.046	4.79SerVal: 4.79 ± 0.042	1.102SerTrp: 1.102 ± 0.019	1.854SerTyr: 1.854 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.42ThrAla: 5.42 ± 0.035	0.726ThrCys: 0.726 ± 0.017	2.833ThrAsp: 2.833 ± 0.026	2.804ThrGlu: 2.804 ± 0.034	1.829ThrPhe: 1.829 ± 0.024	3.86ThrGly: 3.86 ± 0.054	1.131ThrHis: 1.131 ± 0.017	2.49ThrIle: 2.49 ± 0.031	2.311ThrLys: 2.311 ± 0.03	4.904ThrLeu: 4.904 ± 0.04	1.268ThrMet: 1.268 ± 0.019	1.672ThrAsn: 1.672 ± 0.02	3.872ThrPro: 3.872 ± 0.043	1.81ThrGln: 1.81 ± 0.024	3.298ThrArg: 3.298 ± 0.033	4.87ThrSer: 4.87 ± 0.043	4.277ThrThr: 4.277 ± 0.061	3.658ThrVal: 3.658 ± 0.04	0.769ThrTrp: 0.769 ± 0.014	1.312ThrTyr: 1.312 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	6.078ValAla: 6.078 ± 0.048	0.917ValCys: 0.917 ± 0.02	4.33ValAsp: 4.33 ± 0.032	4.035ValGlu: 4.035 ± 0.038	2.432ValPhe: 2.432 ± 0.032	4.2ValGly: 4.2 ± 0.041	1.36ValHis: 1.36 ± 0.02	2.692ValIle: 2.692 ± 0.03	2.886ValLys: 2.886 ± 0.028	5.707ValLeu: 5.707 ± 0.045	1.454ValMet: 1.454 ± 0.017	2.102ValAsn: 2.102 ± 0.022	3.622ValPro: 3.622 ± 0.032	2.293ValGln: 2.293 ± 0.023	4.123ValArg: 4.123 ± 0.037	4.838ValSer: 4.838 ± 0.04	3.516ValThr: 3.516 ± 0.035	4.948ValVal: 4.948 ± 0.044	0.847ValTrp: 0.847 ± 0.017	1.612ValTyr: 1.612 ± 0.024	0.0ValXaa: 0.0 ± 0.0
Trp	1.108TrpAla: 1.108 ± 0.02	0.197TrpCys: 0.197 ± 0.008	0.876TrpAsp: 0.876 ± 0.017	0.771TrpGlu: 0.771 ± 0.015	0.502TrpPhe: 0.502 ± 0.012	0.793TrpGly: 0.793 ± 0.016	0.378TrpHis: 0.378 ± 0.011	0.651TrpIle: 0.651 ± 0.014	0.686TrpLys: 0.686 ± 0.014	1.404TrpLeu: 1.404 ± 0.022	0.344TrpMet: 0.344 ± 0.009	0.571TrpAsn: 0.571 ± 0.014	0.644TrpPro: 0.644 ± 0.013	0.547TrpGln: 0.547 ± 0.012	1.098TrpArg: 1.098 ± 0.016	1.003TrpSer: 1.003 ± 0.018	0.896TrpThr: 0.896 ± 0.016	0.768TrpVal: 0.768 ± 0.018	0.271TrpTrp: 0.271 ± 0.01	0.366TrpTyr: 0.366 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.993TyrAla: 1.993 ± 0.026	0.392TyrCys: 0.392 ± 0.011	1.615TyrAsp: 1.615 ± 0.022	1.38TyrGlu: 1.38 ± 0.02	0.98TyrPhe: 0.98 ± 0.015	2.035TyrGly: 2.035 ± 0.042	0.688TyrHis: 0.688 ± 0.015	1.005TyrIle: 1.005 ± 0.015	0.935TyrLys: 0.935 ± 0.019	2.405TyrLeu: 2.405 ± 0.026	0.562TyrMet: 0.562 ± 0.012	0.848TyrAsn: 0.848 ± 0.016	1.266TyrPro: 1.266 ± 0.021	0.922TyrGln: 0.922 ± 0.015	1.716TyrArg: 1.716 ± 0.023	1.771TyrSer: 1.771 ± 0.025	1.201TyrThr: 1.201 ± 0.022	1.598TyrVal: 1.598 ± 0.027	0.394TyrTrp: 0.394 ± 0.012	0.744TyrTyr: 0.744 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6946 proteins (3813413 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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