Amino acid dipepetide frequency for Torque teno virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.817AlaAla: 10.817 ± 4.399
0.601AlaCys: 0.601 ± 0.555
2.404AlaAsp: 2.404 ± 0.616
4.207AlaGlu: 4.207 ± 1.579
1.803AlaPhe: 1.803 ± 1.136
6.01AlaGly: 6.01 ± 1.861
0.601AlaHis: 0.601 ± 0.379
0.0AlaIle: 0.0 ± 0.0
1.803AlaLys: 1.803 ± 1.062
11.418AlaLeu: 11.418 ± 4.592
4.207AlaMet: 4.207 ± 2.196
3.606AlaAsn: 3.606 ± 1.403
7.212AlaPro: 7.212 ± 2.419
0.601AlaGln: 0.601 ± 0.611
4.808AlaArg: 4.808 ± 0.952
3.606AlaSer: 3.606 ± 1.545
6.611AlaThr: 6.611 ± 0.537
6.01AlaVal: 6.01 ± 1.137
1.202AlaTrp: 1.202 ± 0.757
0.601AlaTyr: 0.601 ± 0.379
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.601CysAsp: 0.601 ± 0.379
0.0CysGlu: 0.0 ± 0.0
0.601CysPhe: 0.601 ± 0.379
4.207CysGly: 4.207 ± 1.579
0.0CysHis: 0.0 ± 0.0
0.601CysIle: 0.601 ± 0.379
1.803CysLys: 1.803 ± 0.987
1.202CysLeu: 1.202 ± 0.757
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.803CysPro: 1.803 ± 1.062
0.601CysGln: 0.601 ± 0.611
0.0CysArg: 0.0 ± 0.0
1.202CysSer: 1.202 ± 0.757
0.601CysThr: 0.601 ± 0.379
0.601CysVal: 0.601 ± 0.379
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.005AspAla: 3.005 ± 0.93
0.0AspCys: 0.0 ± 0.0
2.404AspAsp: 2.404 ± 0.616
3.606AspGlu: 3.606 ± 1.938
4.808AspPhe: 4.808 ± 1.232
5.409AspGly: 5.409 ± 1.477
0.0AspHis: 0.0 ± 0.0
1.202AspIle: 1.202 ± 0.757
1.803AspLys: 1.803 ± 1.136
2.404AspLeu: 2.404 ± 1.515
2.404AspMet: 2.404 ± 0.616
2.404AspAsn: 2.404 ± 1.515
3.005AspPro: 3.005 ± 1.342
1.803AspGln: 1.803 ± 0.693
1.202AspArg: 1.202 ± 0.757
1.202AspSer: 1.202 ± 0.513
0.0AspThr: 0.0 ± 0.0
1.803AspVal: 1.803 ± 0.663
1.202AspTrp: 1.202 ± 0.501
0.601AspTyr: 0.601 ± 0.379
0.0AspXaa: 0.0 ± 0.0
Glu
1.202GluAla: 1.202 ± 0.501
0.601GluCys: 0.601 ± 0.611
1.202GluAsp: 1.202 ± 0.757
9.014GluGlu: 9.014 ± 0.979
2.404GluPhe: 2.404 ± 0.616
3.005GluGly: 3.005 ± 0.326
0.601GluHis: 0.601 ± 0.379
1.803GluIle: 1.803 ± 1.136
0.0GluLys: 0.0 ± 0.0
4.207GluLeu: 4.207 ± 0.495
0.601GluMet: 0.601 ± 0.568
2.404GluAsn: 2.404 ± 0.95
4.808GluPro: 4.808 ± 1.907
1.202GluGln: 1.202 ± 0.757
6.01GluArg: 6.01 ± 2.379
4.207GluSer: 4.207 ± 0.781
2.404GluThr: 2.404 ± 0.95
3.606GluVal: 3.606 ± 0.347
0.0GluTrp: 0.0 ± 0.0
1.202GluTyr: 1.202 ± 0.721
0.0GluXaa: 0.0 ± 0.0
Phe
3.005PheAla: 3.005 ± 0.326
0.601PheCys: 0.601 ± 0.379
0.0PheAsp: 0.0 ± 0.0
0.601PheGlu: 0.601 ± 0.379
0.0PhePhe: 0.0 ± 0.0
3.606PheGly: 3.606 ± 0.347
0.601PheHis: 0.601 ± 0.379
1.202PheIle: 1.202 ± 0.757
1.803PheLys: 1.803 ± 1.136
4.207PheLeu: 4.207 ± 0.648
1.803PheMet: 1.803 ± 0.969
2.404PheAsn: 2.404 ± 0.999
2.404PhePro: 2.404 ± 0.999
2.404PheGln: 2.404 ± 0.999
1.803PheArg: 1.803 ± 1.136
1.803PheSer: 1.803 ± 0.663
1.202PheThr: 1.202 ± 0.501
2.404PheVal: 2.404 ± 0.616
0.601PheTrp: 0.601 ± 0.379
1.202PheTyr: 1.202 ± 0.501
0.0PheXaa: 0.0 ± 0.0
Gly
6.01GlyAla: 6.01 ± 1.137
1.803GlyCys: 1.803 ± 0.969
7.812GlyAsp: 7.812 ± 2.74
0.601GlyGlu: 0.601 ± 0.379
0.601GlyPhe: 0.601 ± 0.379
13.221GlyGly: 13.221 ± 4.214
2.404GlyHis: 2.404 ± 0.616
4.207GlyIle: 4.207 ± 1.579
5.409GlyLys: 5.409 ± 0.91
10.216GlyLeu: 10.216 ± 4.126
0.0GlyMet: 0.0 ± 0.0
7.212GlyAsn: 7.212 ± 1.848
6.01GlyPro: 6.01 ± 0.596
4.207GlyGln: 4.207 ± 0.495
9.014GlyArg: 9.014 ± 0.722
1.202GlySer: 1.202 ± 0.721
2.404GlyThr: 2.404 ± 1.351
0.601GlyVal: 0.601 ± 0.379
0.601GlyTrp: 0.601 ± 0.379
2.404GlyTyr: 2.404 ± 1.515
0.0GlyXaa: 0.0 ± 0.0
His
2.404HisAla: 2.404 ± 0.616
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.803HisGlu: 1.803 ± 0.663
0.0HisPhe: 0.0 ± 0.0
3.606HisGly: 3.606 ± 1.938
0.0HisHis: 0.0 ± 0.0
2.404HisIle: 2.404 ± 0.616
1.202HisLys: 1.202 ± 0.757
1.803HisLeu: 1.803 ± 0.693
0.0HisMet: 0.0 ± 0.0
3.005HisAsn: 3.005 ± 0.326
4.808HisPro: 4.808 ± 1.232
0.601HisGln: 0.601 ± 0.379
4.808HisArg: 4.808 ± 1.833
2.404HisSer: 2.404 ± 1.025
2.404HisThr: 2.404 ± 0.616
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.601HisTyr: 0.601 ± 0.379
0.0HisXaa: 0.0 ± 0.0
Ile
0.601IleAla: 0.601 ± 0.611
1.202IleCys: 1.202 ± 0.757
1.202IleAsp: 1.202 ± 0.757
0.601IleGlu: 0.601 ± 0.555
1.803IlePhe: 1.803 ± 0.693
2.404IleGly: 2.404 ± 0.616
0.601IleHis: 0.601 ± 0.611
2.404IleIle: 2.404 ± 1.515
2.404IleLys: 2.404 ± 1.515
1.202IleLeu: 1.202 ± 0.757
0.0IleMet: 0.0 ± 0.0
1.202IleAsn: 1.202 ± 0.757
1.803IlePro: 1.803 ± 0.693
1.803IleGln: 1.803 ± 1.136
4.207IleArg: 4.207 ± 1.579
1.202IleSer: 1.202 ± 0.757
2.404IleThr: 2.404 ± 0.616
0.601IleVal: 0.601 ± 0.379
0.0IleTrp: 0.0 ± 0.0
3.005IleTyr: 3.005 ± 1.893
0.0IleXaa: 0.0 ± 0.0
Lys
5.409LysAla: 5.409 ± 1.477
1.803LysCys: 1.803 ± 1.136
1.803LysAsp: 1.803 ± 0.693
2.404LysGlu: 2.404 ± 0.95
1.803LysPhe: 1.803 ± 1.136
6.611LysGly: 6.611 ± 0.755
0.601LysHis: 0.601 ± 0.379
1.202LysIle: 1.202 ± 0.501
10.817LysLys: 10.817 ± 3.886
3.005LysLeu: 3.005 ± 0.326
1.202LysMet: 1.202 ± 0.456
2.404LysAsn: 2.404 ± 0.956
5.409LysPro: 5.409 ± 0.898
1.803LysGln: 1.803 ± 0.663
6.01LysArg: 6.01 ± 0.687
3.606LysSer: 3.606 ± 1.326
2.404LysThr: 2.404 ± 0.999
2.404LysVal: 2.404 ± 1.515
1.803LysTrp: 1.803 ± 1.136
0.601LysTyr: 0.601 ± 0.379
0.0LysXaa: 0.0 ± 0.0
Leu
4.207LeuAla: 4.207 ± 0.453
0.0LeuCys: 0.0 ± 0.0
5.409LeuAsp: 5.409 ± 0.91
4.808LeuGlu: 4.808 ± 0.541
1.803LeuPhe: 1.803 ± 0.458
4.808LeuGly: 4.808 ± 1.232
6.611LeuHis: 6.611 ± 2.854
1.803LeuIle: 1.803 ± 1.136
3.606LeuLys: 3.606 ± 0.347
4.808LeuLeu: 4.808 ± 1.901
1.202LeuMet: 1.202 ± 1.058
3.606LeuAsn: 3.606 ± 1.0
7.812LeuPro: 7.812 ± 2.063
1.202LeuGln: 1.202 ± 0.757
4.808LeuArg: 4.808 ± 2.435
5.409LeuSer: 5.409 ± 0.954
2.404LeuThr: 2.404 ± 0.999
4.808LeuVal: 4.808 ± 1.232
3.005LeuTrp: 3.005 ± 0.326
3.005LeuTyr: 3.005 ± 1.893
0.0LeuXaa: 0.0 ± 0.0
Met
3.005MetAla: 3.005 ± 0.326
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.601MetGlu: 0.601 ± 0.555
1.803MetPhe: 1.803 ± 0.969
2.404MetGly: 2.404 ± 0.616
0.601MetHis: 0.601 ± 0.379
0.601MetIle: 0.601 ± 0.379
0.601MetLys: 0.601 ± 0.379
3.005MetLeu: 3.005 ± 0.326
0.601MetMet: 0.601 ± 0.379
1.803MetAsn: 1.803 ± 0.969
0.601MetPro: 0.601 ± 0.379
0.601MetGln: 0.601 ± 0.379
0.0MetArg: 0.0 ± 0.0
0.601MetSer: 0.601 ± 0.379
0.601MetThr: 0.601 ± 0.379
0.601MetVal: 0.601 ± 0.379
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.202AsnAla: 1.202 ± 0.757
0.601AsnCys: 0.601 ± 0.611
1.803AsnAsp: 1.803 ± 0.969
2.404AsnGlu: 2.404 ± 1.351
3.005AsnPhe: 3.005 ± 1.893
1.202AsnGly: 1.202 ± 0.757
0.601AsnHis: 0.601 ± 0.379
1.202AsnIle: 1.202 ± 0.757
1.202AsnLys: 1.202 ± 0.501
4.207AsnLeu: 4.207 ± 2.004
1.202AsnMet: 1.202 ± 0.757
1.803AsnAsn: 1.803 ± 0.693
5.409AsnPro: 5.409 ± 0.126
1.803AsnGln: 1.803 ± 0.969
3.005AsnArg: 3.005 ± 0.67
4.207AsnSer: 4.207 ± 2.992
3.005AsnThr: 3.005 ± 1.286
3.005AsnVal: 3.005 ± 0.93
1.202AsnTrp: 1.202 ± 0.757
3.606AsnTyr: 3.606 ± 1.403
0.0AsnXaa: 0.0 ± 0.0
Pro
9.615ProAla: 9.615 ± 4.923
1.202ProCys: 1.202 ± 0.757
2.404ProAsp: 2.404 ± 0.616
6.01ProGlu: 6.01 ± 1.706
2.404ProPhe: 2.404 ± 0.999
10.216ProGly: 10.216 ± 2.735
0.601ProHis: 0.601 ± 0.379
4.207ProIle: 4.207 ± 0.781
4.808ProLys: 4.808 ± 1.24
1.803ProLeu: 1.803 ± 1.136
1.803ProMet: 1.803 ± 1.136
2.404ProAsn: 2.404 ± 0.616
16.827ProPro: 16.827 ± 7.276
3.005ProGln: 3.005 ± 1.464
6.611ProArg: 6.611 ± 1.54
5.409ProSer: 5.409 ± 1.061
4.808ProThr: 4.808 ± 1.264
5.409ProVal: 5.409 ± 2.084
2.404ProTrp: 2.404 ± 0.616
1.803ProTyr: 1.803 ± 0.693
0.0ProXaa: 0.0 ± 0.0
Gln
2.404GlnAla: 2.404 ± 1.515
0.601GlnCys: 0.601 ± 0.379
1.202GlnAsp: 1.202 ± 0.757
1.202GlnGlu: 1.202 ± 0.757
1.803GlnPhe: 1.803 ± 0.969
1.803GlnGly: 1.803 ± 0.693
0.0GlnHis: 0.0 ± 0.0
0.601GlnIle: 0.601 ± 0.379
1.803GlnLys: 1.803 ± 0.458
3.005GlnLeu: 3.005 ± 1.342
0.0GlnMet: 0.0 ± 0.0
1.803GlnAsn: 1.803 ± 0.663
4.808GlnPro: 4.808 ± 0.553
6.01GlnGln: 6.01 ± 3.787
2.404GlnArg: 2.404 ± 0.879
1.202GlnSer: 1.202 ± 0.513
1.202GlnThr: 1.202 ± 0.501
2.404GlnVal: 2.404 ± 0.95
1.202GlnTrp: 1.202 ± 0.501
0.601GlnTyr: 0.601 ± 0.379
0.0GlnXaa: 0.0 ± 0.0
Arg
11.418ArgAla: 11.418 ± 3.79
0.601ArgCys: 0.601 ± 0.611
2.404ArgAsp: 2.404 ± 0.999
3.606ArgGlu: 3.606 ± 0.626
1.202ArgPhe: 1.202 ± 0.501
7.212ArgGly: 7.212 ± 2.231
5.409ArgHis: 5.409 ± 0.91
1.202ArgIle: 1.202 ± 0.501
7.212ArgLys: 7.212 ± 1.492
4.808ArgLeu: 4.808 ± 0.553
0.601ArgMet: 0.601 ± 0.379
1.202ArgAsn: 1.202 ± 0.513
6.01ArgPro: 6.01 ± 1.366
1.202ArgGln: 1.202 ± 0.757
22.837ArgArg: 22.837 ± 4.143
4.207ArgSer: 4.207 ± 1.509
4.808ArgThr: 4.808 ± 0.411
4.808ArgVal: 4.808 ± 0.541
1.803ArgTrp: 1.803 ± 1.136
2.404ArgTyr: 2.404 ± 0.616
0.0ArgXaa: 0.0 ± 0.0
Ser
2.404SerAla: 2.404 ± 0.431
0.601SerCys: 0.601 ± 0.379
1.803SerAsp: 1.803 ± 1.062
5.409SerGlu: 5.409 ± 2.229
1.803SerPhe: 1.803 ± 1.136
3.005SerGly: 3.005 ± 1.006
3.606SerHis: 3.606 ± 0.626
1.202SerIle: 1.202 ± 0.757
3.606SerLys: 3.606 ± 1.538
7.212SerLeu: 7.212 ± 1.393
0.601SerMet: 0.601 ± 0.514
3.005SerAsn: 3.005 ± 2.257
4.207SerPro: 4.207 ± 0.781
2.404SerGln: 2.404 ± 0.879
4.207SerArg: 4.207 ± 0.781
8.413SerSer: 8.413 ± 4.731
3.005SerThr: 3.005 ± 1.552
3.005SerVal: 3.005 ± 1.006
0.601SerTrp: 0.601 ± 0.379
0.601SerTyr: 0.601 ± 0.379
0.0SerXaa: 0.0 ± 0.0
Thr
6.01ThrAla: 6.01 ± 1.861
0.0ThrCys: 0.0 ± 0.0
4.808ThrAsp: 4.808 ± 2.435
0.601ThrGlu: 0.601 ± 0.379
3.005ThrPhe: 3.005 ± 1.342
1.803ThrGly: 1.803 ± 0.969
1.202ThrHis: 1.202 ± 0.721
2.404ThrIle: 2.404 ± 0.95
4.808ThrLys: 4.808 ± 0.541
2.404ThrLeu: 2.404 ± 1.515
0.0ThrMet: 0.0 ± 0.0
2.404ThrAsn: 2.404 ± 1.515
3.005ThrPro: 3.005 ± 1.397
3.606ThrGln: 3.606 ± 1.7
3.005ThrArg: 3.005 ± 1.123
5.409ThrSer: 5.409 ± 1.653
2.404ThrThr: 2.404 ± 1.025
1.202ThrVal: 1.202 ± 0.501
1.202ThrTrp: 1.202 ± 0.757
1.202ThrTyr: 1.202 ± 0.757
0.0ThrXaa: 0.0 ± 0.0
Val
4.808ValAla: 4.808 ± 1.907
2.404ValCys: 2.404 ± 0.616
2.404ValAsp: 2.404 ± 1.515
0.0ValGlu: 0.0 ± 0.0
0.601ValPhe: 0.601 ± 0.379
1.803ValGly: 1.803 ± 0.987
4.808ValHis: 4.808 ± 1.232
1.202ValIle: 1.202 ± 0.757
4.808ValLys: 4.808 ± 1.004
3.005ValLeu: 3.005 ± 1.286
0.0ValMet: 0.0 ± 0.0
0.601ValAsn: 0.601 ± 0.379
6.01ValPro: 6.01 ± 2.011
0.601ValGln: 0.601 ± 0.379
6.611ValArg: 6.611 ± 1.33
1.803ValSer: 1.803 ± 0.969
3.005ValThr: 3.005 ± 1.342
1.803ValVal: 1.803 ± 1.136
0.0ValTrp: 0.0 ± 0.0
1.202ValTyr: 1.202 ± 0.757
0.0ValXaa: 0.0 ± 0.0
Trp
0.601TrpAla: 0.601 ± 0.555
0.0TrpCys: 0.0 ± 0.0
0.601TrpAsp: 0.601 ± 0.379
0.601TrpGlu: 0.601 ± 0.379
0.0TrpPhe: 0.0 ± 0.0
1.202TrpGly: 1.202 ± 0.757
2.404TrpHis: 2.404 ± 0.616
0.0TrpIle: 0.0 ± 0.0
0.601TrpLys: 0.601 ± 0.379
0.601TrpLeu: 0.601 ± 0.555
0.601TrpMet: 0.601 ± 0.379
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.601TrpGln: 0.601 ± 0.379
3.005TrpArg: 3.005 ± 0.326
1.202TrpSer: 1.202 ± 0.757
2.404TrpThr: 2.404 ± 1.515
1.803TrpVal: 1.803 ± 1.136
1.803TrpTrp: 1.803 ± 1.136
3.005TrpTyr: 3.005 ± 0.326
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.202TyrCys: 1.202 ± 0.501
0.0TyrAsp: 0.0 ± 0.0
2.404TyrGlu: 2.404 ± 0.616
2.404TyrPhe: 2.404 ± 1.515
2.404TyrGly: 2.404 ± 0.616
0.601TyrHis: 0.601 ± 0.379
1.202TyrIle: 1.202 ± 0.757
3.005TyrLys: 3.005 ± 0.67
1.202TyrLeu: 1.202 ± 0.501
0.601TyrMet: 0.601 ± 0.379
2.404TyrAsn: 2.404 ± 0.999
1.803TyrPro: 1.803 ± 0.693
0.0TyrGln: 0.0 ± 0.0
0.601TyrArg: 0.601 ± 0.379
2.404TyrSer: 2.404 ± 1.515
2.404TyrThr: 2.404 ± 1.515
0.601TyrVal: 0.601 ± 0.379
2.404TyrTrp: 2.404 ± 0.616
1.202TyrTyr: 1.202 ± 0.757
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1665 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski