Amino acid dipepetide frequency for Acinetobacter phage vB_AbaM_IME285

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.024AlaAla: 5.024 ± 0.904
0.718AlaCys: 0.718 ± 0.211
3.875AlaAsp: 3.875 ± 0.644
3.875AlaGlu: 3.875 ± 0.379
2.584AlaPhe: 2.584 ± 0.441
4.019AlaGly: 4.019 ± 0.467
1.005AlaHis: 1.005 ± 0.275
5.526AlaIle: 5.526 ± 0.601
6.1AlaLys: 6.1 ± 0.673
6.244AlaLeu: 6.244 ± 0.767
2.225AlaMet: 2.225 ± 0.431
3.732AlaAsn: 3.732 ± 0.551
2.225AlaPro: 2.225 ± 0.413
3.158AlaGln: 3.158 ± 0.655
2.799AlaArg: 2.799 ± 0.424
4.234AlaSer: 4.234 ± 0.621
4.306AlaThr: 4.306 ± 0.682
4.019AlaVal: 4.019 ± 0.514
0.789AlaTrp: 0.789 ± 0.213
2.942AlaTyr: 2.942 ± 0.454
0.0AlaXaa: 0.0 ± 0.0
Cys
0.502CysAla: 0.502 ± 0.187
0.144CysCys: 0.144 ± 0.097
1.005CysAsp: 1.005 ± 0.272
0.861CysGlu: 0.861 ± 0.245
0.574CysPhe: 0.574 ± 0.198
1.148CysGly: 1.148 ± 0.291
0.144CysHis: 0.144 ± 0.088
0.502CysIle: 0.502 ± 0.172
1.579CysLys: 1.579 ± 0.376
0.789CysLeu: 0.789 ± 0.22
0.287CysMet: 0.287 ± 0.151
0.287CysAsn: 0.287 ± 0.146
0.287CysPro: 0.287 ± 0.143
0.287CysGln: 0.287 ± 0.131
0.574CysArg: 0.574 ± 0.205
0.718CysSer: 0.718 ± 0.23
0.574CysThr: 0.574 ± 0.215
1.148CysVal: 1.148 ± 0.3
0.215CysTrp: 0.215 ± 0.106
0.646CysTyr: 0.646 ± 0.228
0.0CysXaa: 0.0 ± 0.0
Asp
4.091AspAla: 4.091 ± 0.559
0.718AspCys: 0.718 ± 0.193
3.875AspAsp: 3.875 ± 0.715
4.162AspGlu: 4.162 ± 0.762
2.799AspPhe: 2.799 ± 0.432
5.957AspGly: 5.957 ± 0.657
0.646AspHis: 0.646 ± 0.215
3.373AspIle: 3.373 ± 0.479
4.521AspLys: 4.521 ± 0.715
4.88AspLeu: 4.88 ± 0.557
1.435AspMet: 1.435 ± 0.302
2.009AspAsn: 2.009 ± 0.312
1.722AspPro: 1.722 ± 0.268
2.727AspGln: 2.727 ± 0.417
2.799AspArg: 2.799 ± 0.368
2.871AspSer: 2.871 ± 0.577
3.158AspThr: 3.158 ± 0.458
4.162AspVal: 4.162 ± 0.5
1.364AspTrp: 1.364 ± 0.338
2.512AspTyr: 2.512 ± 0.379
0.0AspXaa: 0.0 ± 0.0
Glu
4.88GluAla: 4.88 ± 0.59
0.359GluCys: 0.359 ± 0.136
2.942GluAsp: 2.942 ± 0.661
4.521GluGlu: 4.521 ± 0.699
3.445GluPhe: 3.445 ± 0.541
4.45GluGly: 4.45 ± 0.479
1.005GluHis: 1.005 ± 0.265
5.454GluIle: 5.454 ± 0.676
4.45GluLys: 4.45 ± 0.597
5.957GluLeu: 5.957 ± 0.766
2.225GluMet: 2.225 ± 0.52
3.66GluAsn: 3.66 ± 0.584
1.435GluPro: 1.435 ± 0.366
2.871GluGln: 2.871 ± 0.458
1.651GluArg: 1.651 ± 0.348
5.024GluSer: 5.024 ± 0.403
2.44GluThr: 2.44 ± 0.377
4.45GluVal: 4.45 ± 0.502
1.077GluTrp: 1.077 ± 0.364
3.301GluTyr: 3.301 ± 0.499
0.0GluXaa: 0.0 ± 0.0
Phe
3.732PheAla: 3.732 ± 0.578
1.148PheCys: 1.148 ± 0.274
2.871PheAsp: 2.871 ± 0.395
2.727PheGlu: 2.727 ± 0.485
1.364PhePhe: 1.364 ± 0.346
3.23PheGly: 3.23 ± 0.432
0.718PheHis: 0.718 ± 0.2
3.373PheIle: 3.373 ± 0.436
3.445PheLys: 3.445 ± 0.459
2.942PheLeu: 2.942 ± 0.447
1.292PheMet: 1.292 ± 0.257
2.655PheAsn: 2.655 ± 0.398
1.077PhePro: 1.077 ± 0.246
1.077PheGln: 1.077 ± 0.296
1.794PheArg: 1.794 ± 0.311
2.297PheSer: 2.297 ± 0.382
2.368PheThr: 2.368 ± 0.407
2.44PheVal: 2.44 ± 0.458
0.718PheTrp: 0.718 ± 0.253
2.368PheTyr: 2.368 ± 0.462
0.0PheXaa: 0.0 ± 0.0
Gly
5.526GlyAla: 5.526 ± 0.817
1.077GlyCys: 1.077 ± 0.274
4.019GlyAsp: 4.019 ± 0.6
4.091GlyGlu: 4.091 ± 0.489
4.378GlyPhe: 4.378 ± 0.599
5.383GlyGly: 5.383 ± 0.847
1.148GlyHis: 1.148 ± 0.267
4.45GlyIle: 4.45 ± 0.532
4.808GlyLys: 4.808 ± 0.584
6.028GlyLeu: 6.028 ± 0.483
2.225GlyMet: 2.225 ± 0.342
4.378GlyAsn: 4.378 ± 0.604
0.718GlyPro: 0.718 ± 0.31
2.655GlyGln: 2.655 ± 0.544
2.942GlyArg: 2.942 ± 0.404
4.88GlySer: 4.88 ± 0.611
3.517GlyThr: 3.517 ± 0.626
6.1GlyVal: 6.1 ± 0.64
1.077GlyTrp: 1.077 ± 0.297
3.373GlyTyr: 3.373 ± 0.398
0.0GlyXaa: 0.0 ± 0.0
His
1.077HisAla: 1.077 ± 0.273
0.072HisCys: 0.072 ± 0.055
1.364HisAsp: 1.364 ± 0.333
1.507HisGlu: 1.507 ± 0.348
0.646HisPhe: 0.646 ± 0.231
1.292HisGly: 1.292 ± 0.309
0.359HisHis: 0.359 ± 0.151
1.579HisIle: 1.579 ± 0.292
1.507HisLys: 1.507 ± 0.334
1.148HisLeu: 1.148 ± 0.277
0.502HisMet: 0.502 ± 0.221
0.933HisAsn: 0.933 ± 0.235
0.574HisPro: 0.574 ± 0.193
0.789HisGln: 0.789 ± 0.258
0.359HisArg: 0.359 ± 0.169
0.861HisSer: 0.861 ± 0.281
0.933HisThr: 0.933 ± 0.247
0.789HisVal: 0.789 ± 0.214
0.072HisTrp: 0.072 ± 0.061
0.789HisTyr: 0.789 ± 0.263
0.0HisXaa: 0.0 ± 0.0
Ile
4.521IleAla: 4.521 ± 0.593
1.22IleCys: 1.22 ± 0.304
5.239IleAsp: 5.239 ± 0.508
6.028IleGlu: 6.028 ± 0.753
1.938IlePhe: 1.938 ± 0.325
5.311IleGly: 5.311 ± 0.517
1.722IleHis: 1.722 ± 0.396
4.091IleIle: 4.091 ± 0.57
7.823IleLys: 7.823 ± 0.842
4.665IleLeu: 4.665 ± 0.541
1.507IleMet: 1.507 ± 0.291
3.66IleAsn: 3.66 ± 0.533
3.445IlePro: 3.445 ± 0.551
1.722IleGln: 1.722 ± 0.409
2.512IleArg: 2.512 ± 0.402
4.593IleSer: 4.593 ± 0.535
3.66IleThr: 3.66 ± 0.57
4.019IleVal: 4.019 ± 0.472
0.789IleTrp: 0.789 ± 0.181
2.584IleTyr: 2.584 ± 0.391
0.0IleXaa: 0.0 ± 0.0
Lys
6.531LysAla: 6.531 ± 0.847
0.933LysCys: 0.933 ± 0.296
4.019LysAsp: 4.019 ± 0.641
5.741LysGlu: 5.741 ± 0.712
2.942LysPhe: 2.942 ± 0.44
5.383LysGly: 5.383 ± 0.511
1.148LysHis: 1.148 ± 0.289
5.311LysIle: 5.311 ± 0.735
5.526LysLys: 5.526 ± 0.794
6.603LysLeu: 6.603 ± 0.586
2.799LysMet: 2.799 ± 0.425
4.162LysAsn: 4.162 ± 0.53
2.512LysPro: 2.512 ± 0.452
2.727LysGln: 2.727 ± 0.485
3.66LysArg: 3.66 ± 0.417
4.593LysSer: 4.593 ± 0.686
4.091LysThr: 4.091 ± 0.557
5.454LysVal: 5.454 ± 0.878
1.077LysTrp: 1.077 ± 0.286
2.655LysTyr: 2.655 ± 0.462
0.0LysXaa: 0.0 ± 0.0
Leu
6.315LeuAla: 6.315 ± 0.734
0.431LeuCys: 0.431 ± 0.159
5.095LeuAsp: 5.095 ± 0.641
6.028LeuGlu: 6.028 ± 0.601
2.871LeuPhe: 2.871 ± 0.465
5.454LeuGly: 5.454 ± 0.617
1.507LeuHis: 1.507 ± 0.382
6.746LeuIle: 6.746 ± 0.798
6.818LeuLys: 6.818 ± 0.762
6.1LeuLeu: 6.1 ± 0.644
2.153LeuMet: 2.153 ± 0.397
5.813LeuAsn: 5.813 ± 0.688
2.368LeuPro: 2.368 ± 0.405
2.009LeuGln: 2.009 ± 0.408
3.23LeuArg: 3.23 ± 0.533
5.741LeuSer: 5.741 ± 0.493
4.521LeuThr: 4.521 ± 0.481
4.665LeuVal: 4.665 ± 0.406
0.789LeuTrp: 0.789 ± 0.205
2.153LeuTyr: 2.153 ± 0.372
0.0LeuXaa: 0.0 ± 0.0
Met
1.435MetAla: 1.435 ± 0.313
0.431MetCys: 0.431 ± 0.179
1.435MetAsp: 1.435 ± 0.388
1.364MetGlu: 1.364 ± 0.262
1.507MetPhe: 1.507 ± 0.389
2.368MetGly: 2.368 ± 0.471
0.431MetHis: 0.431 ± 0.178
1.507MetIle: 1.507 ± 0.272
1.866MetLys: 1.866 ± 0.317
2.297MetLeu: 2.297 ± 0.404
0.646MetMet: 0.646 ± 0.176
2.655MetAsn: 2.655 ± 0.473
1.077MetPro: 1.077 ± 0.253
1.866MetGln: 1.866 ± 0.339
1.292MetArg: 1.292 ± 0.325
2.871MetSer: 2.871 ± 0.464
2.297MetThr: 2.297 ± 0.423
0.933MetVal: 0.933 ± 0.246
0.215MetTrp: 0.215 ± 0.115
0.646MetTyr: 0.646 ± 0.197
0.0MetXaa: 0.0 ± 0.0
Asn
3.588AsnAla: 3.588 ± 0.551
0.502AsnCys: 0.502 ± 0.223
3.875AsnAsp: 3.875 ± 0.417
3.517AsnGlu: 3.517 ± 0.531
1.938AsnPhe: 1.938 ± 0.427
4.952AsnGly: 4.952 ± 0.626
1.077AsnHis: 1.077 ± 0.251
4.019AsnIle: 4.019 ± 0.539
2.942AsnLys: 2.942 ± 0.499
4.952AsnLeu: 4.952 ± 0.598
1.722AsnMet: 1.722 ± 0.288
3.014AsnAsn: 3.014 ± 0.532
2.655AsnPro: 2.655 ± 0.413
2.584AsnGln: 2.584 ± 0.424
2.081AsnArg: 2.081 ± 0.476
3.301AsnSer: 3.301 ± 0.557
3.517AsnThr: 3.517 ± 0.497
3.373AsnVal: 3.373 ± 0.57
0.431AsnTrp: 0.431 ± 0.156
2.799AsnTyr: 2.799 ± 0.42
0.0AsnXaa: 0.0 ± 0.0
Pro
1.507ProAla: 1.507 ± 0.314
0.287ProCys: 0.287 ± 0.158
2.225ProAsp: 2.225 ± 0.361
2.512ProGlu: 2.512 ± 0.385
1.364ProPhe: 1.364 ± 0.314
0.144ProGly: 0.144 ± 0.108
0.646ProHis: 0.646 ± 0.245
2.225ProIle: 2.225 ± 0.39
2.368ProLys: 2.368 ± 0.439
2.512ProLeu: 2.512 ± 0.523
1.005ProMet: 1.005 ± 0.269
2.009ProAsn: 2.009 ± 0.42
0.574ProPro: 0.574 ± 0.233
1.435ProGln: 1.435 ± 0.281
1.077ProArg: 1.077 ± 0.269
2.297ProSer: 2.297 ± 0.443
2.297ProThr: 2.297 ± 0.407
1.938ProVal: 1.938 ± 0.342
0.215ProTrp: 0.215 ± 0.124
1.722ProTyr: 1.722 ± 0.352
0.0ProXaa: 0.0 ± 0.0
Gln
3.158GlnAla: 3.158 ± 0.441
0.287GlnCys: 0.287 ± 0.153
2.368GlnAsp: 2.368 ± 0.408
2.584GlnGlu: 2.584 ± 0.48
1.938GlnPhe: 1.938 ± 0.464
2.655GlnGly: 2.655 ± 0.53
0.502GlnHis: 0.502 ± 0.181
2.153GlnIle: 2.153 ± 0.473
3.66GlnLys: 3.66 ± 0.529
3.373GlnLeu: 3.373 ± 0.612
1.077GlnMet: 1.077 ± 0.281
1.866GlnAsn: 1.866 ± 0.38
0.861GlnPro: 0.861 ± 0.226
1.794GlnGln: 1.794 ± 0.376
1.651GlnArg: 1.651 ± 0.384
2.081GlnSer: 2.081 ± 0.418
2.225GlnThr: 2.225 ± 0.32
2.225GlnVal: 2.225 ± 0.403
0.574GlnTrp: 0.574 ± 0.204
1.579GlnTyr: 1.579 ± 0.412
0.0GlnXaa: 0.0 ± 0.0
Arg
2.368ArgAla: 2.368 ± 0.435
1.005ArgCys: 1.005 ± 0.221
2.44ArgAsp: 2.44 ± 0.374
2.727ArgGlu: 2.727 ± 0.422
1.794ArgPhe: 1.794 ± 0.383
2.44ArgGly: 2.44 ± 0.368
1.22ArgHis: 1.22 ± 0.284
3.158ArgIle: 3.158 ± 0.43
3.66ArgLys: 3.66 ± 0.527
3.014ArgLeu: 3.014 ± 0.494
0.789ArgMet: 0.789 ± 0.21
1.579ArgAsn: 1.579 ± 0.275
1.077ArgPro: 1.077 ± 0.282
1.22ArgGln: 1.22 ± 0.314
1.22ArgArg: 1.22 ± 0.249
2.727ArgSer: 2.727 ± 0.41
1.938ArgThr: 1.938 ± 0.415
2.871ArgVal: 2.871 ± 0.419
0.574ArgTrp: 0.574 ± 0.201
1.651ArgTyr: 1.651 ± 0.413
0.0ArgXaa: 0.0 ± 0.0
Ser
3.373SerAla: 3.373 ± 0.503
0.502SerCys: 0.502 ± 0.158
3.158SerAsp: 3.158 ± 0.379
3.875SerGlu: 3.875 ± 0.635
2.871SerPhe: 2.871 ± 0.478
5.526SerGly: 5.526 ± 0.601
1.148SerHis: 1.148 ± 0.308
5.454SerIle: 5.454 ± 0.552
5.024SerLys: 5.024 ± 0.615
6.1SerLeu: 6.1 ± 0.659
2.153SerMet: 2.153 ± 0.462
3.301SerAsn: 3.301 ± 0.447
1.722SerPro: 1.722 ± 0.371
2.727SerGln: 2.727 ± 0.38
2.584SerArg: 2.584 ± 0.465
4.019SerSer: 4.019 ± 0.67
3.517SerThr: 3.517 ± 0.449
3.804SerVal: 3.804 ± 0.595
0.789SerTrp: 0.789 ± 0.261
2.153SerTyr: 2.153 ± 0.407
0.0SerXaa: 0.0 ± 0.0
Thr
3.517ThrAla: 3.517 ± 0.542
1.005ThrCys: 1.005 ± 0.271
3.301ThrAsp: 3.301 ± 0.443
2.081ThrGlu: 2.081 ± 0.382
2.297ThrPhe: 2.297 ± 0.37
4.521ThrGly: 4.521 ± 0.729
0.789ThrHis: 0.789 ± 0.249
3.732ThrIle: 3.732 ± 0.551
3.23ThrLys: 3.23 ± 0.483
4.952ThrLeu: 4.952 ± 0.687
1.364ThrMet: 1.364 ± 0.312
2.871ThrAsn: 2.871 ± 0.508
2.655ThrPro: 2.655 ± 0.359
2.081ThrGln: 2.081 ± 0.422
2.009ThrArg: 2.009 ± 0.327
2.799ThrSer: 2.799 ± 0.455
3.086ThrThr: 3.086 ± 0.746
4.378ThrVal: 4.378 ± 0.568
1.364ThrTrp: 1.364 ± 0.304
1.651ThrTyr: 1.651 ± 0.312
0.0ThrXaa: 0.0 ± 0.0
Val
4.521ValAla: 4.521 ± 0.597
0.574ValCys: 0.574 ± 0.174
3.66ValAsp: 3.66 ± 0.362
4.521ValGlu: 4.521 ± 0.642
3.373ValPhe: 3.373 ± 0.475
4.665ValGly: 4.665 ± 0.6
0.861ValHis: 0.861 ± 0.224
4.737ValIle: 4.737 ± 0.811
5.024ValLys: 5.024 ± 0.454
4.162ValLeu: 4.162 ± 0.617
2.009ValMet: 2.009 ± 0.382
4.593ValAsn: 4.593 ± 0.548
1.507ValPro: 1.507 ± 0.277
2.368ValGln: 2.368 ± 0.427
2.368ValArg: 2.368 ± 0.43
3.732ValSer: 3.732 ± 0.439
3.014ValThr: 3.014 ± 0.498
4.306ValVal: 4.306 ± 0.596
1.005ValTrp: 1.005 ± 0.247
3.086ValTyr: 3.086 ± 0.485
0.0ValXaa: 0.0 ± 0.0
Trp
0.933TrpAla: 0.933 ± 0.293
0.287TrpCys: 0.287 ± 0.161
0.718TrpAsp: 0.718 ± 0.217
0.718TrpGlu: 0.718 ± 0.202
1.148TrpPhe: 1.148 ± 0.252
0.646TrpGly: 0.646 ± 0.192
0.359TrpHis: 0.359 ± 0.153
0.861TrpIle: 0.861 ± 0.282
0.789TrpLys: 0.789 ± 0.193
1.005TrpLeu: 1.005 ± 0.247
0.574TrpMet: 0.574 ± 0.193
1.148TrpAsn: 1.148 ± 0.224
0.144TrpPro: 0.144 ± 0.119
0.718TrpGln: 0.718 ± 0.22
0.789TrpArg: 0.789 ± 0.285
0.933TrpSer: 0.933 ± 0.256
0.574TrpThr: 0.574 ± 0.209
0.933TrpVal: 0.933 ± 0.222
0.287TrpTrp: 0.287 ± 0.146
0.144TrpTyr: 0.144 ± 0.078
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.799TyrAla: 2.799 ± 0.372
0.574TyrCys: 0.574 ± 0.219
2.297TyrAsp: 2.297 ± 0.534
2.225TyrGlu: 2.225 ± 0.423
1.866TyrPhe: 1.866 ± 0.37
3.23TyrGly: 3.23 ± 0.537
0.718TyrHis: 0.718 ± 0.211
2.799TyrIle: 2.799 ± 0.451
2.727TyrLys: 2.727 ± 0.456
3.086TyrLeu: 3.086 ± 0.46
1.077TyrMet: 1.077 ± 0.238
2.512TyrAsn: 2.512 ± 0.406
1.722TyrPro: 1.722 ± 0.425
1.794TyrGln: 1.794 ± 0.411
2.081TyrArg: 2.081 ± 0.438
3.23TyrSer: 3.23 ± 0.461
1.651TyrThr: 1.651 ± 0.315
2.081TyrVal: 2.081 ± 0.333
0.287TyrTrp: 0.287 ± 0.142
1.22TyrTyr: 1.22 ± 0.343
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 85 proteins (13935 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski