Amino acid dipepetide frequency for Togninia minima (strain UCR-PA7) (Esca disease fungus) (Phaeoacremonium aleophilum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.339AlaAla: 10.339 ± 0.082	0.961AlaCys: 0.961 ± 0.018	4.875AlaAsp: 4.875 ± 0.037	5.71AlaGlu: 5.71 ± 0.048	3.345AlaPhe: 3.345 ± 0.027	6.648AlaGly: 6.648 ± 0.049	1.721AlaHis: 1.721 ± 0.023	4.637AlaIle: 4.637 ± 0.037	4.78AlaLys: 4.78 ± 0.047	7.917AlaLeu: 7.917 ± 0.048	2.18AlaMet: 2.18 ± 0.026	3.131AlaAsn: 3.131 ± 0.03	4.713AlaPro: 4.713 ± 0.043	3.466AlaGln: 3.466 ± 0.036	4.775AlaArg: 4.775 ± 0.039	6.776AlaSer: 6.776 ± 0.051	5.419AlaThr: 5.419 ± 0.04	6.022AlaVal: 6.022 ± 0.04	1.257AlaTrp: 1.257 ± 0.018	2.331AlaTyr: 2.331 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	0.866CysAla: 0.866 ± 0.013	0.185CysCys: 0.185 ± 0.008	0.591CysAsp: 0.591 ± 0.012	0.51CysGlu: 0.51 ± 0.011	0.502CysPhe: 0.502 ± 0.012	0.902CysGly: 0.902 ± 0.018	0.259CysHis: 0.259 ± 0.008	0.644CysIle: 0.644 ± 0.012	0.484CysLys: 0.484 ± 0.013	1.06CysLeu: 1.06 ± 0.017	0.257CysMet: 0.257 ± 0.008	0.394CysAsn: 0.394 ± 0.011	0.559CysPro: 0.559 ± 0.013	0.359CysGln: 0.359 ± 0.01	0.549CysArg: 0.549 ± 0.012	0.734CysSer: 0.734 ± 0.014	0.621CysThr: 0.621 ± 0.014	0.718CysVal: 0.718 ± 0.015	0.171CysTrp: 0.171 ± 0.007	0.334CysTyr: 0.334 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	5.225AspAla: 5.225 ± 0.037	0.581AspCys: 0.581 ± 0.013	4.886AspAsp: 4.886 ± 0.057	4.955AspGlu: 4.955 ± 0.048	2.455AspPhe: 2.455 ± 0.029	4.521AspGly: 4.521 ± 0.041	1.177AspHis: 1.177 ± 0.021	3.29AspIle: 3.29 ± 0.034	2.908AspLys: 2.908 ± 0.031	5.21AspLeu: 5.21 ± 0.038	1.384AspMet: 1.384 ± 0.018	1.979AspAsn: 1.979 ± 0.024	3.365AspPro: 3.365 ± 0.033	1.893AspGln: 1.893 ± 0.024	2.989AspArg: 2.989 ± 0.036	3.91AspSer: 3.91 ± 0.041	2.974AspThr: 2.974 ± 0.03	4.06AspVal: 4.06 ± 0.035	0.949AspTrp: 0.949 ± 0.016	1.761AspTyr: 1.761 ± 0.025	0.0AspXaa: 0.0 ± 0.0
Glu	5.943GluAla: 5.943 ± 0.049	0.55GluCys: 0.55 ± 0.013	4.586GluAsp: 4.586 ± 0.046	5.852GluGlu: 5.852 ± 0.068	2.05GluPhe: 2.05 ± 0.021	3.939GluGly: 3.939 ± 0.036	1.394GluHis: 1.394 ± 0.02	3.233GluIle: 3.233 ± 0.032	4.239GluLys: 4.239 ± 0.044	5.433GluLeu: 5.433 ± 0.049	1.558GluMet: 1.558 ± 0.02	2.332GluAsn: 2.332 ± 0.027	2.717GluPro: 2.717 ± 0.038	2.511GluGln: 2.511 ± 0.035	3.843GluArg: 3.843 ± 0.041	3.934GluSer: 3.934 ± 0.037	3.562GluThr: 3.562 ± 0.032	3.864GluVal: 3.864 ± 0.032	0.909GluTrp: 0.909 ± 0.013	1.771GluTyr: 1.771 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.283PheAla: 3.283 ± 0.028	0.538PheCys: 0.538 ± 0.012	2.424PheAsp: 2.424 ± 0.025	2.297PheGlu: 2.297 ± 0.023	1.733PhePhe: 1.733 ± 0.023	3.173PheGly: 3.173 ± 0.039	0.826PheHis: 0.826 ± 0.015	1.985PheIle: 1.985 ± 0.027	1.743PheLys: 1.743 ± 0.022	3.449PheLeu: 3.449 ± 0.036	0.877PheMet: 0.877 ± 0.013	1.534PheAsn: 1.534 ± 0.02	1.846PhePro: 1.846 ± 0.024	1.348PheGln: 1.348 ± 0.021	1.856PheArg: 1.856 ± 0.023	2.801PheSer: 2.801 ± 0.028	2.273PheThr: 2.273 ± 0.028	2.651PheVal: 2.651 ± 0.027	0.663PheTrp: 0.663 ± 0.015	1.183PheTyr: 1.183 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	6.09GlyAla: 6.09 ± 0.05	0.832GlyCys: 0.832 ± 0.018	4.057GlyAsp: 4.057 ± 0.039	3.935GlyGlu: 3.935 ± 0.033	3.116GlyPhe: 3.116 ± 0.03	6.697GlyGly: 6.697 ± 0.072	1.637GlyHis: 1.637 ± 0.022	3.87GlyIle: 3.87 ± 0.034	3.991GlyLys: 3.991 ± 0.031	6.336GlyLeu: 6.336 ± 0.05	1.716GlyMet: 1.716 ± 0.023	2.673GlyAsn: 2.673 ± 0.03	3.244GlyPro: 3.244 ± 0.038	2.647GlyGln: 2.647 ± 0.028	4.06GlyArg: 4.06 ± 0.041	5.699GlySer: 5.699 ± 0.041	4.31GlyThr: 4.31 ± 0.04	4.923GlyVal: 4.923 ± 0.038	1.271GlyTrp: 1.271 ± 0.019	2.322GlyTyr: 2.322 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.702HisAla: 1.702 ± 0.027	0.262HisCys: 0.262 ± 0.008	1.251HisAsp: 1.251 ± 0.019	1.246HisGlu: 1.246 ± 0.02	0.91HisPhe: 0.91 ± 0.014	1.648HisGly: 1.648 ± 0.024	0.714HisHis: 0.714 ± 0.017	1.14HisIle: 1.14 ± 0.016	0.937HisLys: 0.937 ± 0.016	1.942HisLeu: 1.942 ± 0.024	0.478HisMet: 0.478 ± 0.011	0.768HisAsn: 0.768 ± 0.015	1.424HisPro: 1.424 ± 0.024	0.797HisGln: 0.797 ± 0.015	1.276HisArg: 1.276 ± 0.022	1.414HisSer: 1.414 ± 0.022	1.076HisThr: 1.076 ± 0.018	1.399HisVal: 1.399 ± 0.019	0.316HisTrp: 0.316 ± 0.008	0.68HisTyr: 0.68 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	4.628IleAla: 4.628 ± 0.039	0.697IleCys: 0.697 ± 0.013	3.119IleAsp: 3.119 ± 0.033	3.089IleGlu: 3.089 ± 0.029	2.082IlePhe: 2.082 ± 0.027	3.603IleGly: 3.603 ± 0.037	1.123IleHis: 1.123 ± 0.018	2.746IleIle: 2.746 ± 0.033	2.513IleLys: 2.513 ± 0.029	4.527IleLeu: 4.527 ± 0.043	1.147IleMet: 1.147 ± 0.02	1.962IleAsn: 1.962 ± 0.023	2.941IlePro: 2.941 ± 0.031	1.892IleGln: 1.892 ± 0.024	2.73IleArg: 2.73 ± 0.029	3.537IleSer: 3.537 ± 0.031	3.046IleThr: 3.046 ± 0.029	3.579IleVal: 3.579 ± 0.037	0.751IleTrp: 0.751 ± 0.014	1.463IleTyr: 1.463 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	5.086LysAla: 5.086 ± 0.042	0.437LysCys: 0.437 ± 0.011	3.296LysAsp: 3.296 ± 0.035	3.915LysGlu: 3.915 ± 0.045	1.67LysPhe: 1.67 ± 0.021	3.377LysGly: 3.377 ± 0.033	1.131LysHis: 1.131 ± 0.018	2.584LysIle: 2.584 ± 0.03	4.034LysLys: 4.034 ± 0.065	4.436LysLeu: 4.436 ± 0.04	1.162LysMet: 1.162 ± 0.016	1.897LysAsn: 1.897 ± 0.023	2.745LysPro: 2.745 ± 0.029	1.976LysGln: 1.976 ± 0.026	3.356LysArg: 3.356 ± 0.038	3.57LysSer: 3.57 ± 0.039	3.127LysThr: 3.127 ± 0.027	3.237LysVal: 3.237 ± 0.032	0.736LysTrp: 0.736 ± 0.015	1.594LysTyr: 1.594 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	8.089LeuAla: 8.089 ± 0.052	1.032LeuCys: 1.032 ± 0.016	5.305LeuAsp: 5.305 ± 0.04	5.557LeuGlu: 5.557 ± 0.049	3.271LeuPhe: 3.271 ± 0.034	6.155LeuGly: 6.155 ± 0.04	1.914LeuHis: 1.914 ± 0.024	4.102LeuIle: 4.102 ± 0.039	4.585LeuLys: 4.585 ± 0.041	7.808LeuLeu: 7.808 ± 0.054	1.846LeuMet: 1.846 ± 0.024	3.154LeuAsn: 3.154 ± 0.028	4.947LeuPro: 4.947 ± 0.039	3.549LeuGln: 3.549 ± 0.035	5.299LeuArg: 5.299 ± 0.039	6.475LeuSer: 6.475 ± 0.046	4.831LeuThr: 4.831 ± 0.039	5.591LeuVal: 5.591 ± 0.043	1.156LeuTrp: 1.156 ± 0.016	2.401LeuTyr: 2.401 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.458MetAla: 2.458 ± 0.026	0.241MetCys: 0.241 ± 0.008	1.315MetAsp: 1.315 ± 0.019	1.305MetGlu: 1.305 ± 0.021	0.831MetPhe: 0.831 ± 0.016	1.627MetGly: 1.627 ± 0.021	0.445MetHis: 0.445 ± 0.009	1.118MetIle: 1.118 ± 0.015	1.128MetLys: 1.128 ± 0.018	1.919MetLeu: 1.919 ± 0.025	0.621MetMet: 0.621 ± 0.014	0.818MetAsn: 0.818 ± 0.015	1.215MetPro: 1.215 ± 0.018	0.868MetGln: 0.868 ± 0.015	1.264MetArg: 1.264 ± 0.02	1.778MetSer: 1.778 ± 0.022	1.37MetThr: 1.37 ± 0.019	1.425MetVal: 1.425 ± 0.019	0.303MetTrp: 0.303 ± 0.009	0.582MetTyr: 0.582 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.273AsnAla: 3.273 ± 0.031	0.402AsnCys: 0.402 ± 0.01	2.012AsnAsp: 2.012 ± 0.024	2.033AsnGlu: 2.033 ± 0.024	1.467AsnPhe: 1.467 ± 0.02	3.301AsnGly: 3.301 ± 0.041	0.721AsnHis: 0.721 ± 0.015	2.115AsnIle: 2.115 ± 0.025	1.7AsnLys: 1.7 ± 0.021	3.259AsnLeu: 3.259 ± 0.03	0.888AsnMet: 0.888 ± 0.015	1.48AsnAsn: 1.48 ± 0.023	2.294AsnPro: 2.294 ± 0.027	1.249AsnGln: 1.249 ± 0.019	1.771AsnArg: 1.771 ± 0.022	2.46AsnSer: 2.46 ± 0.025	2.097AsnThr: 2.097 ± 0.028	2.516AsnVal: 2.516 ± 0.025	0.591AsnTrp: 0.591 ± 0.013	1.132AsnTyr: 1.132 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.024ProAla: 5.024 ± 0.047	0.401ProCys: 0.401 ± 0.011	3.23ProAsp: 3.23 ± 0.035	3.886ProGlu: 3.886 ± 0.039	1.973ProPhe: 1.973 ± 0.025	3.887ProGly: 3.887 ± 0.038	1.12ProHis: 1.12 ± 0.017	2.451ProIle: 2.451 ± 0.03	2.728ProLys: 2.728 ± 0.033	4.271ProLeu: 4.271 ± 0.032	1.01ProMet: 1.01 ± 0.018	2.035ProAsn: 2.035 ± 0.024	4.117ProPro: 4.117 ± 0.062	2.092ProGln: 2.092 ± 0.029	2.751ProArg: 2.751 ± 0.027	4.66ProSer: 4.66 ± 0.044	3.542ProThr: 3.542 ± 0.031	3.51ProVal: 3.51 ± 0.03	0.7ProTrp: 0.7 ± 0.012	1.496ProTyr: 1.496 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.487GlnAla: 3.487 ± 0.035	0.359GlnCys: 0.359 ± 0.01	2.059GlnAsp: 2.059 ± 0.024	2.4GlnGlu: 2.4 ± 0.029	1.304GlnPhe: 1.304 ± 0.019	2.449GlnGly: 2.449 ± 0.025	0.868GlnHis: 0.868 ± 0.013	1.914GlnIle: 1.914 ± 0.024	2.076GlnLys: 2.076 ± 0.023	3.346GlnLeu: 3.346 ± 0.035	0.903GlnMet: 0.903 ± 0.019	1.483GlnAsn: 1.483 ± 0.023	2.097GlnPro: 2.097 ± 0.025	2.13GlnGln: 2.13 ± 0.039	2.331GlnArg: 2.331 ± 0.026	2.576GlnSer: 2.576 ± 0.027	2.16GlnThr: 2.16 ± 0.025	2.242GlnVal: 2.242 ± 0.024	0.584GlnTrp: 0.584 ± 0.011	1.157GlnTyr: 1.157 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	4.546ArgAla: 4.546 ± 0.04	0.538ArgCys: 0.538 ± 0.011	3.373ArgAsp: 3.373 ± 0.039	3.75ArgGlu: 3.75 ± 0.042	2.073ArgPhe: 2.073 ± 0.023	3.542ArgGly: 3.542 ± 0.039	1.285ArgHis: 1.285 ± 0.02	2.787ArgIle: 2.787 ± 0.029	3.451ArgLys: 3.451 ± 0.036	5.036ArgLeu: 5.036 ± 0.043	1.279ArgMet: 1.279 ± 0.017	2.035ArgAsn: 2.035 ± 0.025	2.846ArgPro: 2.846 ± 0.029	2.347ArgGln: 2.347 ± 0.03	4.381ArgArg: 4.381 ± 0.049	3.807ArgSer: 3.807 ± 0.039	2.888ArgThr: 2.888 ± 0.03	3.348ArgVal: 3.348 ± 0.029	0.902ArgTrp: 0.902 ± 0.015	1.601ArgTyr: 1.601 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.227SerAla: 6.227 ± 0.047	0.703SerCys: 0.703 ± 0.016	4.09SerAsp: 4.09 ± 0.048	3.862SerGlu: 3.862 ± 0.038	2.849SerPhe: 2.849 ± 0.027	5.592SerGly: 5.592 ± 0.046	1.541SerHis: 1.541 ± 0.023	3.754SerIle: 3.754 ± 0.031	3.75SerLys: 3.75 ± 0.038	6.272SerLeu: 6.272 ± 0.04	1.587SerMet: 1.587 ± 0.021	2.647SerAsn: 2.647 ± 0.028	4.28SerPro: 4.28 ± 0.048	2.775SerGln: 2.775 ± 0.028	3.966SerArg: 3.966 ± 0.033	6.988SerSer: 6.988 ± 0.072	4.729SerThr: 4.729 ± 0.046	4.426SerVal: 4.426 ± 0.035	1.078SerTrp: 1.078 ± 0.017	2.046SerTyr: 2.046 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.42ThrAla: 5.42 ± 0.042	0.638ThrCys: 0.638 ± 0.012	3.027ThrAsp: 3.027 ± 0.028	3.191ThrGlu: 3.191 ± 0.033	2.306ThrPhe: 2.306 ± 0.026	4.518ThrGly: 4.518 ± 0.042	1.125ThrHis: 1.125 ± 0.017	3.174ThrIle: 3.174 ± 0.033	2.867ThrLys: 2.867 ± 0.032	4.998ThrLeu: 4.998 ± 0.037	1.216ThrMet: 1.216 ± 0.018	2.161ThrAsn: 2.161 ± 0.027	3.891ThrPro: 3.891 ± 0.037	1.977ThrGln: 1.977 ± 0.022	2.773ThrArg: 2.773 ± 0.025	4.612ThrSer: 4.612 ± 0.045	4.087ThrThr: 4.087 ± 0.046	4.022ThrVal: 4.022 ± 0.031	0.844ThrTrp: 0.844 ± 0.017	1.719ThrTyr: 1.719 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	5.844ValAla: 5.844 ± 0.04	0.772ValCys: 0.772 ± 0.016	4.138ValAsp: 4.138 ± 0.038	4.192ValGlu: 4.192 ± 0.036	2.667ValPhe: 2.667 ± 0.029	4.48ValGly: 4.48 ± 0.04	1.337ValHis: 1.337 ± 0.02	3.322ValIle: 3.322 ± 0.031	3.311ValLys: 3.311 ± 0.027	5.796ValLeu: 5.796 ± 0.046	1.456ValMet: 1.456 ± 0.022	2.414ValAsn: 2.414 ± 0.028	3.583ValPro: 3.583 ± 0.032	2.381ValGln: 2.381 ± 0.027	3.423ValArg: 3.423 ± 0.031	4.499ValSer: 4.499 ± 0.04	3.844ValThr: 3.844 ± 0.034	4.778ValVal: 4.778 ± 0.037	0.957ValTrp: 0.957 ± 0.017	1.888ValTyr: 1.888 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.191TrpAla: 1.191 ± 0.019	0.177TrpCys: 0.177 ± 0.007	0.994TrpAsp: 0.994 ± 0.016	0.869TrpGlu: 0.869 ± 0.014	0.585TrpPhe: 0.585 ± 0.012	1.037TrpGly: 1.037 ± 0.019	0.352TrpHis: 0.352 ± 0.01	0.782TrpIle: 0.782 ± 0.013	0.853TrpLys: 0.853 ± 0.012	1.351TrpLeu: 1.351 ± 0.017	0.38TrpMet: 0.38 ± 0.011	0.66TrpAsn: 0.66 ± 0.015	0.592TrpPro: 0.592 ± 0.014	0.585TrpGln: 0.585 ± 0.014	0.91TrpArg: 0.91 ± 0.014	0.989TrpSer: 0.989 ± 0.017	0.936TrpThr: 0.936 ± 0.017	0.94TrpVal: 0.94 ± 0.015	0.28TrpTrp: 0.28 ± 0.009	0.451TrpTyr: 0.451 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.281TyrAla: 2.281 ± 0.028	0.394TyrCys: 0.394 ± 0.011	1.844TyrAsp: 1.844 ± 0.024	1.666TyrGlu: 1.666 ± 0.021	1.297TyrPhe: 1.297 ± 0.018	2.329TyrGly: 2.329 ± 0.03	0.693TyrHis: 0.693 ± 0.015	1.524TyrIle: 1.524 ± 0.022	1.289TyrLys: 1.289 ± 0.019	2.702TyrLeu: 2.702 ± 0.029	0.685TyrMet: 0.685 ± 0.014	1.205TyrAsn: 1.205 ± 0.017	1.47TyrPro: 1.47 ± 0.018	1.084TyrGln: 1.084 ± 0.016	1.51TyrArg: 1.51 ± 0.019	1.944TyrSer: 1.944 ± 0.026	1.673TyrThr: 1.673 ± 0.023	1.829TyrVal: 1.829 ± 0.021	0.495TyrTrp: 0.495 ± 0.011	1.049TyrTyr: 1.049 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8833 proteins (3911874 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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