Amino acid dipepetide frequency for Pothos latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.862AlaAla: 5.862 ± 2.088
5.275AlaCys: 5.275 ± 2.304
0.586AlaAsp: 0.586 ± 0.52
0.586AlaGlu: 0.586 ± 0.381
1.172AlaPhe: 1.172 ± 0.762
5.275AlaGly: 5.275 ± 1.507
2.931AlaHis: 2.931 ± 0.743
10.551AlaIle: 10.551 ± 0.601
2.931AlaLys: 2.931 ± 0.934
4.689AlaLeu: 4.689 ± 1.183
1.758AlaMet: 1.758 ± 1.19
4.689AlaAsn: 4.689 ± 0.719
5.275AlaPro: 5.275 ± 1.133
2.345AlaGln: 2.345 ± 1.969
1.172AlaArg: 1.172 ± 0.762
5.862AlaSer: 5.862 ± 1.919
3.517AlaThr: 3.517 ± 2.013
2.931AlaVal: 2.931 ± 0.934
0.0AlaTrp: 0.0 ± 0.0
2.345AlaTyr: 2.345 ± 0.788
0.0AlaXaa: 0.0 ± 0.0
Cys
2.931CysAla: 2.931 ± 0.934
1.758CysCys: 1.758 ± 0.504
1.172CysAsp: 1.172 ± 0.762
1.172CysGlu: 1.172 ± 1.039
0.586CysPhe: 0.586 ± 0.381
0.586CysGly: 0.586 ± 0.381
0.586CysHis: 0.586 ± 0.81
0.0CysIle: 0.0 ± 0.0
2.931CysLys: 2.931 ± 1.298
4.689CysLeu: 4.689 ± 1.573
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.758CysPro: 1.758 ± 0.889
1.172CysGln: 1.172 ± 0.76
2.345CysArg: 2.345 ± 1.52
1.758CysSer: 1.758 ± 0.889
0.586CysThr: 0.586 ± 0.381
4.689CysVal: 4.689 ± 2.061
0.0CysTrp: 0.0 ± 0.0
0.586CysTyr: 0.586 ± 0.52
0.0CysXaa: 0.0 ± 0.0
Asp
2.345AspAla: 2.345 ± 1.524
2.345AspCys: 2.345 ± 1.08
4.103AspAsp: 4.103 ± 1.846
2.931AspGlu: 2.931 ± 0.804
0.0AspPhe: 0.0 ± 0.0
3.517AspGly: 3.517 ± 1.663
0.0AspHis: 0.0 ± 0.0
0.586AspIle: 0.586 ± 0.381
1.172AspLys: 1.172 ± 0.432
3.517AspLeu: 3.517 ± 0.781
1.758AspMet: 1.758 ± 0.773
2.931AspAsn: 2.931 ± 0.784
2.931AspPro: 2.931 ± 1.296
1.172AspGln: 1.172 ± 0.432
4.103AspArg: 4.103 ± 1.22
2.931AspSer: 2.931 ± 1.31
0.0AspThr: 0.0 ± 0.0
5.862AspVal: 5.862 ± 0.604
0.586AspTrp: 0.586 ± 0.381
1.758AspTyr: 1.758 ± 1.273
0.0AspXaa: 0.0 ± 0.0
Glu
2.931GluAla: 2.931 ± 0.934
0.0GluCys: 0.0 ± 0.0
0.586GluAsp: 0.586 ± 0.381
3.517GluGlu: 3.517 ± 1.15
1.758GluPhe: 1.758 ± 0.735
1.758GluGly: 1.758 ± 0.611
0.586GluHis: 0.586 ± 0.381
2.931GluIle: 2.931 ± 0.908
4.689GluLys: 4.689 ± 2.519
4.103GluLeu: 4.103 ± 1.515
0.0GluMet: 0.0 ± 0.0
1.758GluAsn: 1.758 ± 0.93
1.758GluPro: 1.758 ± 0.877
1.758GluGln: 1.758 ± 0.798
6.448GluArg: 6.448 ± 2.525
4.103GluSer: 4.103 ± 0.775
2.931GluThr: 2.931 ± 0.919
6.448GluVal: 6.448 ± 2.028
1.758GluTrp: 1.758 ± 1.273
2.345GluTyr: 2.345 ± 0.554
0.0GluXaa: 0.0 ± 0.0
Phe
0.586PheAla: 0.586 ± 0.381
3.517PheCys: 3.517 ± 1.159
3.517PheAsp: 3.517 ± 1.158
2.931PheGlu: 2.931 ± 0.784
0.0PhePhe: 0.0 ± 0.0
1.758PheGly: 1.758 ± 0.877
0.586PheHis: 0.586 ± 0.81
0.586PheIle: 0.586 ± 0.52
1.758PheLys: 1.758 ± 0.735
0.0PheLeu: 0.0 ± 0.0
0.586PheMet: 0.586 ± 0.864
1.172PheAsn: 1.172 ± 0.854
2.931PhePro: 2.931 ± 0.804
0.0PheGln: 0.0 ± 0.0
3.517PheArg: 3.517 ± 1.15
0.586PheSer: 0.586 ± 0.711
2.345PheThr: 2.345 ± 1.111
6.448PheVal: 6.448 ± 1.241
0.586PheTrp: 0.586 ± 0.381
1.172PheTyr: 1.172 ± 0.614
0.0PheXaa: 0.0 ± 0.0
Gly
5.862GlyAla: 5.862 ± 1.513
1.172GlyCys: 1.172 ± 0.762
5.275GlyAsp: 5.275 ± 0.751
4.689GlyGlu: 4.689 ± 2.02
4.103GlyPhe: 4.103 ± 1.177
7.62GlyGly: 7.62 ± 2.127
1.758GlyHis: 1.758 ± 1.54
3.517GlyIle: 3.517 ± 0.618
1.758GlyLys: 1.758 ± 0.628
6.448GlyLeu: 6.448 ± 0.638
2.931GlyMet: 2.931 ± 0.91
2.931GlyAsn: 2.931 ± 0.784
2.931GlyPro: 2.931 ± 1.145
2.345GlyGln: 2.345 ± 1.771
5.862GlyArg: 5.862 ± 1.22
4.103GlySer: 4.103 ± 1.808
2.345GlyThr: 2.345 ± 0.865
7.034GlyVal: 7.034 ± 1.824
0.0GlyTrp: 0.0 ± 0.0
3.517GlyTyr: 3.517 ± 2.285
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.586HisCys: 0.586 ± 0.381
1.758HisAsp: 1.758 ± 0.773
0.586HisGlu: 0.586 ± 0.381
0.0HisPhe: 0.0 ± 0.0
2.345HisGly: 2.345 ± 1.499
0.586HisHis: 0.586 ± 0.81
0.586HisIle: 0.586 ± 0.711
1.172HisLys: 1.172 ± 0.614
0.586HisLeu: 0.586 ± 0.52
0.0HisMet: 0.0 ± 0.0
0.586HisAsn: 0.586 ± 0.381
1.758HisPro: 1.758 ± 0.798
1.172HisGln: 1.172 ± 0.614
1.172HisArg: 1.172 ± 0.432
1.172HisSer: 1.172 ± 0.614
1.172HisThr: 1.172 ± 0.971
1.172HisVal: 1.172 ± 0.564
0.0HisTrp: 0.0 ± 0.0
0.586HisTyr: 0.586 ± 0.52
0.0HisXaa: 0.0 ± 0.0
Ile
5.862IleAla: 5.862 ± 1.78
0.586IleCys: 0.586 ± 0.52
2.345IleAsp: 2.345 ± 1.229
2.931IleGlu: 2.931 ± 0.91
1.758IlePhe: 1.758 ± 0.773
2.345IleGly: 2.345 ± 0.554
0.586IleHis: 0.586 ± 0.52
1.758IleIle: 1.758 ± 0.504
1.758IleLys: 1.758 ± 0.877
4.103IleLeu: 4.103 ± 1.734
1.758IleMet: 1.758 ± 0.817
1.758IleAsn: 1.758 ± 0.628
1.758IlePro: 1.758 ± 0.611
2.931IleGln: 2.931 ± 1.785
5.275IleArg: 5.275 ± 2.033
2.345IleSer: 2.345 ± 1.253
7.034IleThr: 7.034 ± 2.478
3.517IleVal: 3.517 ± 1.546
0.586IleTrp: 0.586 ± 0.52
2.345IleTyr: 2.345 ± 0.854
0.0IleXaa: 0.0 ± 0.0
Lys
4.689LysAla: 4.689 ± 1.126
0.0LysCys: 0.0 ± 0.0
2.931LysAsp: 2.931 ± 1.296
1.172LysGlu: 1.172 ± 0.614
2.931LysPhe: 2.931 ± 1.106
4.689LysGly: 4.689 ± 0.923
0.0LysHis: 0.0 ± 0.0
4.103LysIle: 4.103 ± 0.943
1.758LysLys: 1.758 ± 1.484
7.62LysLeu: 7.62 ± 0.85
2.345LysMet: 2.345 ± 0.73
1.758LysAsn: 1.758 ± 0.735
2.931LysPro: 2.931 ± 0.729
1.172LysGln: 1.172 ± 0.614
2.345LysArg: 2.345 ± 0.854
3.517LysSer: 3.517 ± 0.618
1.758LysThr: 1.758 ± 0.735
3.517LysVal: 3.517 ± 1.546
0.586LysTrp: 0.586 ± 0.711
1.172LysTyr: 1.172 ± 0.564
0.0LysXaa: 0.0 ± 0.0
Leu
9.965LeuAla: 9.965 ± 1.327
0.586LeuCys: 0.586 ± 0.81
3.517LeuAsp: 3.517 ± 1.19
4.689LeuGlu: 4.689 ± 1.573
1.758LeuPhe: 1.758 ± 1.559
5.275LeuGly: 5.275 ± 0.806
1.172LeuHis: 1.172 ± 0.432
2.345LeuIle: 2.345 ± 1.375
4.103LeuLys: 4.103 ± 2.149
7.034LeuLeu: 7.034 ± 1.197
2.345LeuMet: 2.345 ± 1.08
2.345LeuAsn: 2.345 ± 0.96
7.62LeuPro: 7.62 ± 2.124
5.275LeuGln: 5.275 ± 1.833
2.345LeuArg: 2.345 ± 1.08
11.137LeuSer: 11.137 ± 2.51
3.517LeuThr: 3.517 ± 0.512
9.379LeuVal: 9.379 ± 1.351
0.586LeuTrp: 0.586 ± 0.381
2.345LeuTyr: 2.345 ± 1.229
0.0LeuXaa: 0.0 ± 0.0
Met
4.103MetAla: 4.103 ± 1.302
1.758MetCys: 1.758 ± 0.504
0.0MetAsp: 0.0 ± 0.0
2.345MetGlu: 2.345 ± 0.959
1.172MetPhe: 1.172 ± 0.564
1.758MetGly: 1.758 ± 0.735
0.0MetHis: 0.0 ± 0.0
1.172MetIle: 1.172 ± 0.564
4.689MetLys: 4.689 ± 1.459
0.586MetLeu: 0.586 ± 0.52
0.586MetMet: 0.586 ± 0.711
1.758MetAsn: 1.758 ± 0.628
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.172MetArg: 1.172 ± 0.564
2.345MetSer: 2.345 ± 1.229
1.172MetThr: 1.172 ± 0.762
2.345MetVal: 2.345 ± 1.08
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.758AsnAla: 1.758 ± 0.877
0.586AsnCys: 0.586 ± 0.381
1.172AsnAsp: 1.172 ± 0.854
1.172AsnGlu: 1.172 ± 0.614
1.172AsnPhe: 1.172 ± 1.004
2.345AsnGly: 2.345 ± 1.673
0.586AsnHis: 0.586 ± 0.381
3.517AsnIle: 3.517 ± 0.512
0.0AsnLys: 0.0 ± 0.0
1.758AsnLeu: 1.758 ± 1.484
1.172AsnMet: 1.172 ± 0.453
2.931AsnAsn: 2.931 ± 1.885
2.345AsnPro: 2.345 ± 1.375
0.0AsnGln: 0.0 ± 0.0
0.586AsnArg: 0.586 ± 0.81
5.275AsnSer: 5.275 ± 0.784
2.345AsnThr: 2.345 ± 0.865
3.517AsnVal: 3.517 ± 1.66
2.345AsnTrp: 2.345 ± 0.552
1.172AsnTyr: 1.172 ± 0.432
0.0AsnXaa: 0.0 ± 0.0
Pro
4.103ProAla: 4.103 ± 1.253
1.172ProCys: 1.172 ± 0.762
2.931ProAsp: 2.931 ± 1.904
2.345ProGlu: 2.345 ± 1.128
4.103ProPhe: 4.103 ± 0.806
1.758ProGly: 1.758 ± 1.559
0.586ProHis: 0.586 ± 0.711
2.345ProIle: 2.345 ± 1.322
2.931ProLys: 2.931 ± 0.784
4.689ProLeu: 4.689 ± 1.59
0.586ProMet: 0.586 ± 0.52
2.345ProAsn: 2.345 ± 1.322
0.0ProPro: 0.0 ± 0.0
1.758ProGln: 1.758 ± 0.504
5.862ProArg: 5.862 ± 2.359
2.345ProSer: 2.345 ± 1.253
1.758ProThr: 1.758 ± 0.773
6.448ProVal: 6.448 ± 1.126
1.172ProTrp: 1.172 ± 1.039
0.586ProTyr: 0.586 ± 0.381
0.0ProXaa: 0.0 ± 0.0
Gln
2.345GlnAla: 2.345 ± 0.96
0.0GlnCys: 0.0 ± 0.0
0.586GlnAsp: 0.586 ± 0.52
0.0GlnGlu: 0.0 ± 0.0
2.931GlnPhe: 2.931 ± 1.944
2.931GlnGly: 2.931 ± 2.494
2.345GlnHis: 2.345 ± 1.524
1.172GlnIle: 1.172 ± 0.432
1.172GlnLys: 1.172 ± 0.614
2.345GlnLeu: 2.345 ± 0.554
0.0GlnMet: 0.0 ± 0.0
0.586GlnAsn: 0.586 ± 0.711
2.931GlnPro: 2.931 ± 1.31
1.172GlnGln: 1.172 ± 0.614
3.517GlnArg: 3.517 ± 1.13
2.345GlnSer: 2.345 ± 1.602
1.758GlnThr: 1.758 ± 1.118
2.345GlnVal: 2.345 ± 1.425
0.0GlnTrp: 0.0 ± 0.0
2.345GlnTyr: 2.345 ± 1.111
0.0GlnXaa: 0.0 ± 0.0
Arg
7.034ArgAla: 7.034 ± 1.108
0.586ArgCys: 0.586 ± 0.81
3.517ArgAsp: 3.517 ± 1.022
2.931ArgGlu: 2.931 ± 1.817
3.517ArgPhe: 3.517 ± 1.486
7.034ArgGly: 7.034 ± 1.763
0.0ArgHis: 0.0 ± 0.0
2.931ArgIle: 2.931 ± 0.743
4.103ArgLys: 4.103 ± 1.483
4.103ArgLeu: 4.103 ± 1.839
1.172ArgMet: 1.172 ± 0.614
0.586ArgAsn: 0.586 ± 0.52
4.689ArgPro: 4.689 ± 2.161
1.172ArgGln: 1.172 ± 0.76
4.103ArgArg: 4.103 ± 0.787
4.689ArgSer: 4.689 ± 1.141
0.0ArgThr: 0.0 ± 0.0
9.379ArgVal: 9.379 ± 1.904
2.345ArgTrp: 2.345 ± 1.08
2.931ArgTyr: 2.931 ± 1.424
0.0ArgXaa: 0.0 ± 0.0
Ser
1.172SerAla: 1.172 ± 0.854
2.345SerCys: 2.345 ± 1.08
2.931SerAsp: 2.931 ± 1.469
5.862SerGlu: 5.862 ± 1.21
2.345SerPhe: 2.345 ± 0.865
7.034SerGly: 7.034 ± 2.455
2.931SerHis: 2.931 ± 1.31
2.345SerIle: 2.345 ± 1.375
5.862SerLys: 5.862 ± 2.843
9.965SerLeu: 9.965 ± 2.03
3.517SerMet: 3.517 ± 1.546
1.758SerAsn: 1.758 ± 1.559
1.172SerPro: 1.172 ± 0.854
3.517SerGln: 3.517 ± 2.364
4.103SerArg: 4.103 ± 2.474
5.862SerSer: 5.862 ± 3.111
4.103SerThr: 4.103 ± 1.922
4.103SerVal: 4.103 ± 0.943
2.931SerTrp: 2.931 ± 1.308
0.586SerTyr: 0.586 ± 0.381
0.0SerXaa: 0.0 ± 0.0
Thr
2.931ThrAla: 2.931 ± 0.729
0.0ThrCys: 0.0 ± 0.0
0.586ThrAsp: 0.586 ± 0.52
2.345ThrGlu: 2.345 ± 1.375
1.758ThrPhe: 1.758 ± 0.877
2.931ThrGly: 2.931 ± 1.831
0.0ThrHis: 0.0 ± 0.0
5.275ThrIle: 5.275 ± 2.823
1.758ThrLys: 1.758 ± 0.811
5.862ThrLeu: 5.862 ± 2.037
1.172ThrMet: 1.172 ± 0.564
1.172ThrAsn: 1.172 ± 0.432
2.345ThrPro: 2.345 ± 1.229
0.586ThrGln: 0.586 ± 0.81
4.103ThrArg: 4.103 ± 1.311
6.448ThrSer: 6.448 ± 1.387
7.034ThrThr: 7.034 ± 3.747
3.517ThrVal: 3.517 ± 0.512
1.172ThrTrp: 1.172 ± 0.432
2.931ThrTyr: 2.931 ± 0.995
0.0ThrXaa: 0.0 ± 0.0
Val
3.517ValAla: 3.517 ± 1.79
3.517ValCys: 3.517 ± 1.637
6.448ValAsp: 6.448 ± 1.176
7.034ValGlu: 7.034 ± 1.468
2.931ValPhe: 2.931 ± 0.946
9.379ValGly: 9.379 ± 2.451
0.586ValHis: 0.586 ± 0.381
3.517ValIle: 3.517 ± 0.512
5.275ValLys: 5.275 ± 1.693
8.792ValLeu: 8.792 ± 1.723
4.103ValMet: 4.103 ± 0.806
2.345ValAsn: 2.345 ± 1.375
4.103ValPro: 4.103 ± 1.459
1.758ValGln: 1.758 ± 0.798
5.862ValArg: 5.862 ± 1.419
3.517ValSer: 3.517 ± 1.129
5.862ValThr: 5.862 ± 1.731
8.792ValVal: 8.792 ± 1.352
0.0ValTrp: 0.0 ± 0.0
5.862ValTyr: 5.862 ± 1.552
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.758TrpCys: 1.758 ± 0.504
0.0TrpAsp: 0.0 ± 0.0
1.758TrpGlu: 1.758 ± 0.773
0.586TrpPhe: 0.586 ± 0.381
1.172TrpGly: 1.172 ± 0.432
1.172TrpHis: 1.172 ± 0.564
1.758TrpIle: 1.758 ± 0.725
0.586TrpLys: 0.586 ± 0.711
2.345TrpLeu: 2.345 ± 0.788
0.0TrpMet: 0.0 ± 0.0
0.586TrpAsn: 0.586 ± 0.52
0.0TrpPro: 0.0 ± 0.0
0.586TrpGln: 0.586 ± 0.381
0.586TrpArg: 0.586 ± 0.711
0.0TrpSer: 0.0 ± 0.0
0.586TrpThr: 0.586 ± 0.381
0.586TrpVal: 0.586 ± 0.52
0.0TrpTrp: 0.0 ± 0.0
0.586TrpTyr: 0.586 ± 0.381
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.758TyrAla: 1.758 ± 0.735
1.758TyrCys: 1.758 ± 0.628
0.586TyrAsp: 0.586 ± 0.81
1.172TyrGlu: 1.172 ± 0.762
0.586TyrPhe: 0.586 ± 0.52
4.103TyrGly: 4.103 ± 0.806
0.0TyrHis: 0.0 ± 0.0
2.345TyrIle: 2.345 ± 0.96
0.586TyrLys: 0.586 ± 0.52
4.103TyrLeu: 4.103 ± 2.031
0.586TyrMet: 0.586 ± 0.487
1.758TyrAsn: 1.758 ± 0.628
0.586TyrPro: 0.586 ± 0.711
2.931TyrGln: 2.931 ± 0.804
2.345TyrArg: 2.345 ± 0.818
4.103TyrSer: 4.103 ± 1.708
4.103TyrThr: 4.103 ± 1.633
1.172TyrVal: 1.172 ± 0.432
0.0TyrTrp: 0.0 ± 0.0
0.586TyrTyr: 0.586 ± 0.52
0.586TyrXaa: 0.586 ± 0.381
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.586XaaGly: 0.586 ± 0.381
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1707 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski