Amino acid dipepetide frequency for Luteitalea pratensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.825AlaAla: 17.825 ± 0.139	1.214AlaCys: 1.214 ± 0.027	6.853AlaAsp: 6.853 ± 0.064	6.081AlaGlu: 6.081 ± 0.06	4.32AlaPhe: 4.32 ± 0.052	10.877AlaGly: 10.877 ± 0.081	2.672AlaHis: 2.672 ± 0.033	5.439AlaIle: 5.439 ± 0.053	2.373AlaLys: 2.373 ± 0.037	13.71AlaLeu: 13.71 ± 0.095	2.928AlaMet: 2.928 ± 0.041	2.668AlaAsn: 2.668 ± 0.043	6.724AlaPro: 6.724 ± 0.066	4.201AlaGln: 4.201 ± 0.052	10.74AlaArg: 10.74 ± 0.085	7.287AlaSer: 7.287 ± 0.063	7.672AlaThr: 7.672 ± 0.069	9.867AlaVal: 9.867 ± 0.08	2.122AlaTrp: 2.122 ± 0.038	2.607AlaTyr: 2.607 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.96CysAla: 0.96 ± 0.023	0.112CysCys: 0.112 ± 0.008	0.457CysAsp: 0.457 ± 0.014	0.37CysGlu: 0.37 ± 0.013	0.242CysPhe: 0.242 ± 0.011	0.803CysGly: 0.803 ± 0.022	0.251CysHis: 0.251 ± 0.014	0.255CysIle: 0.255 ± 0.011	0.117CysLys: 0.117 ± 0.008	0.74CysLeu: 0.74 ± 0.019	0.126CysMet: 0.126 ± 0.007	0.154CysAsn: 0.154 ± 0.009	0.44CysPro: 0.44 ± 0.017	0.206CysGln: 0.206 ± 0.011	0.62CysArg: 0.62 ± 0.018	0.417CysSer: 0.417 ± 0.015	0.446CysThr: 0.446 ± 0.016	0.647CysVal: 0.647 ± 0.018	0.114CysTrp: 0.114 ± 0.007	0.17CysTyr: 0.17 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.977AspAla: 7.977 ± 0.068	0.323AspCys: 0.323 ± 0.013	3.271AspAsp: 3.271 ± 0.046	3.202AspGlu: 3.202 ± 0.045	1.782AspPhe: 1.782 ± 0.028	5.766AspGly: 5.766 ± 0.073	1.14AspHis: 1.14 ± 0.022	2.221AspIle: 2.221 ± 0.032	1.086AspLys: 1.086 ± 0.024	5.625AspLeu: 5.625 ± 0.053	0.938AspMet: 0.938 ± 0.02	1.113AspAsn: 1.113 ± 0.027	3.55AspPro: 3.55 ± 0.039	1.616AspGln: 1.616 ± 0.028	4.591AspArg: 4.591 ± 0.042	2.1AspSer: 2.1 ± 0.033	2.921AspThr: 2.921 ± 0.042	5.481AspVal: 5.481 ± 0.056	0.892AspTrp: 0.892 ± 0.021	1.264AspTyr: 1.264 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	6.716GluAla: 6.716 ± 0.076	0.314GluCys: 0.314 ± 0.012	2.361GluAsp: 2.361 ± 0.04	2.279GluGlu: 2.279 ± 0.04	1.655GluPhe: 1.655 ± 0.03	3.894GluGly: 3.894 ± 0.043	1.215GluHis: 1.215 ± 0.025	2.217GluIle: 2.217 ± 0.033	1.311GluLys: 1.311 ± 0.031	4.724GluLeu: 4.724 ± 0.054	1.127GluMet: 1.127 ± 0.023	1.005GluAsn: 1.005 ± 0.024	2.667GluPro: 2.667 ± 0.036	2.172GluGln: 2.172 ± 0.036	4.978GluArg: 4.978 ± 0.056	2.517GluSer: 2.517 ± 0.042	2.763GluThr: 2.763 ± 0.036	3.931GluVal: 3.931 ± 0.048	0.794GluTrp: 0.794 ± 0.02	1.137GluTyr: 1.137 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	4.038PheAla: 4.038 ± 0.043	0.244PheCys: 0.244 ± 0.012	2.491PheAsp: 2.491 ± 0.031	2.035PheGlu: 2.035 ± 0.032	1.249PhePhe: 1.249 ± 0.026	3.471PheGly: 3.471 ± 0.048	0.702PheHis: 0.702 ± 0.018	1.143PheIle: 1.143 ± 0.024	0.746PheLys: 0.746 ± 0.019	2.981PheLeu: 2.981 ± 0.04	0.606PheMet: 0.606 ± 0.017	0.976PheAsn: 0.976 ± 0.03	1.582PhePro: 1.582 ± 0.027	0.903PheGln: 0.903 ± 0.023	2.316PheArg: 2.316 ± 0.032	1.964PheSer: 1.964 ± 0.034	2.174PheThr: 2.174 ± 0.031	2.96PheVal: 2.96 ± 0.038	0.469PheTrp: 0.469 ± 0.015	0.871PheTyr: 0.871 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	9.815GlyAla: 9.815 ± 0.079	0.757GlyCys: 0.757 ± 0.022	4.636GlyAsp: 4.636 ± 0.048	4.138GlyGlu: 4.138 ± 0.046	3.018GlyPhe: 3.018 ± 0.038	7.543GlyGly: 7.543 ± 0.076	2.034GlyHis: 2.034 ± 0.031	3.649GlyIle: 3.649 ± 0.042	2.304GlyLys: 2.304 ± 0.039	8.535GlyLeu: 8.535 ± 0.082	1.823GlyMet: 1.823 ± 0.026	2.023GlyAsn: 2.023 ± 0.034	4.114GlyPro: 4.114 ± 0.046	3.023GlyGln: 3.023 ± 0.041	7.278GlyArg: 7.278 ± 0.057	4.857GlySer: 4.857 ± 0.052	5.929GlyThr: 5.929 ± 0.053	7.312GlyVal: 7.312 ± 0.055	1.453GlyTrp: 1.453 ± 0.03	2.197GlyTyr: 2.197 ± 0.032	0.0GlyXaa: 0.0 ± 0.0
His	2.833HisAla: 2.833 ± 0.042	0.199HisCys: 0.199 ± 0.01	1.357HisAsp: 1.357 ± 0.026	1.196HisGlu: 1.196 ± 0.025	0.759HisPhe: 0.759 ± 0.02	2.115HisGly: 2.115 ± 0.034	0.569HisHis: 0.569 ± 0.016	0.756HisIle: 0.756 ± 0.019	0.373HisLys: 0.373 ± 0.013	2.191HisLeu: 2.191 ± 0.034	0.431HisMet: 0.431 ± 0.015	0.414HisAsn: 0.414 ± 0.013	1.473HisPro: 1.473 ± 0.025	0.623HisGln: 0.623 ± 0.017	1.694HisArg: 1.694 ± 0.031	0.89HisSer: 0.89 ± 0.019	1.067HisThr: 1.067 ± 0.023	2.091HisVal: 2.091 ± 0.031	0.356HisTrp: 0.356 ± 0.012	0.518HisTyr: 0.518 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	5.825IleAla: 5.825 ± 0.056	0.324IleCys: 0.324 ± 0.013	2.936IleAsp: 2.936 ± 0.039	2.652IleGlu: 2.652 ± 0.039	1.077IlePhe: 1.077 ± 0.024	4.061IleGly: 4.061 ± 0.048	0.79IleHis: 0.79 ± 0.02	1.231IleIle: 1.231 ± 0.027	0.896IleLys: 0.896 ± 0.023	3.013IleLeu: 3.013 ± 0.039	0.511IleMet: 0.511 ± 0.018	1.029IleAsn: 1.029 ± 0.027	1.995IlePro: 1.995 ± 0.031	0.961IleGln: 0.961 ± 0.026	2.806IleArg: 2.806 ± 0.038	1.957IleSer: 1.957 ± 0.034	2.498IleThr: 2.498 ± 0.043	3.949IleVal: 3.949 ± 0.048	0.478IleTrp: 0.478 ± 0.015	0.852IleTyr: 0.852 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.918LysAla: 2.918 ± 0.043	0.111LysCys: 0.111 ± 0.008	1.279LysAsp: 1.279 ± 0.029	1.02LysGlu: 1.02 ± 0.027	0.656LysPhe: 0.656 ± 0.02	1.867LysGly: 1.867 ± 0.032	0.433LysHis: 0.433 ± 0.015	0.86LysIle: 0.86 ± 0.021	0.761LysLys: 0.761 ± 0.022	1.921LysLeu: 1.921 ± 0.036	0.51LysMet: 0.51 ± 0.014	0.531LysAsn: 0.531 ± 0.016	1.359LysPro: 1.359 ± 0.027	0.777LysGln: 0.777 ± 0.02	1.633LysArg: 1.633 ± 0.028	1.119LysSer: 1.119 ± 0.025	1.351LysThr: 1.351 ± 0.027	1.939LysVal: 1.939 ± 0.033	0.307LysTrp: 0.307 ± 0.011	0.579LysTyr: 0.579 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	13.839LeuAla: 13.839 ± 0.104	0.791LeuCys: 0.791 ± 0.021	6.08LeuAsp: 6.08 ± 0.059	5.18LeuGlu: 5.18 ± 0.059	3.189LeuPhe: 3.189 ± 0.047	8.293LeuGly: 8.293 ± 0.074	2.088LeuHis: 2.088 ± 0.033	3.528LeuIle: 3.528 ± 0.045	2.295LeuLys: 2.295 ± 0.033	10.4LeuLeu: 10.4 ± 0.102	1.871LeuMet: 1.871 ± 0.033	2.012LeuAsn: 2.012 ± 0.034	5.748LeuPro: 5.748 ± 0.054	3.341LeuGln: 3.341 ± 0.041	8.097LeuArg: 8.097 ± 0.062	5.496LeuSer: 5.496 ± 0.056	6.077LeuThr: 6.077 ± 0.053	8.709LeuVal: 8.709 ± 0.08	1.297LeuTrp: 1.297 ± 0.029	2.012LeuTyr: 2.012 ± 0.031	0.0LeuXaa: 0.0 ± 0.0
Met	2.659MetAla: 2.659 ± 0.037	0.129MetCys: 0.129 ± 0.007	0.912MetAsp: 0.912 ± 0.025	0.747MetGlu: 0.747 ± 0.02	0.593MetPhe: 0.593 ± 0.018	1.449MetGly: 1.449 ± 0.025	0.44MetHis: 0.44 ± 0.015	0.771MetIle: 0.771 ± 0.019	0.611MetLys: 0.611 ± 0.02	2.152MetLeu: 2.152 ± 0.032	0.416MetMet: 0.416 ± 0.016	0.551MetAsn: 0.551 ± 0.016	1.484MetPro: 1.484 ± 0.031	0.711MetGln: 0.711 ± 0.018	1.865MetArg: 1.865 ± 0.031	1.401MetSer: 1.401 ± 0.025	1.576MetThr: 1.576 ± 0.028	1.46MetVal: 1.46 ± 0.025	0.22MetTrp: 0.22 ± 0.01	0.378MetTyr: 0.378 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.709AsnAla: 2.709 ± 0.047	0.178AsnCys: 0.178 ± 0.009	1.196AsnAsp: 1.196 ± 0.027	0.998AsnGlu: 0.998 ± 0.025	0.813AsnPhe: 0.813 ± 0.025	2.215AsnGly: 2.215 ± 0.039	0.475AsnHis: 0.475 ± 0.016	0.98AsnIle: 0.98 ± 0.023	0.44AsnLys: 0.44 ± 0.016	2.142AsnLeu: 2.142 ± 0.032	0.383AsnMet: 0.383 ± 0.015	0.673AsnAsn: 0.673 ± 0.026	1.61AsnPro: 1.61 ± 0.032	0.689AsnGln: 0.689 ± 0.021	1.619AsnArg: 1.619 ± 0.031	0.999AsnSer: 0.999 ± 0.026	1.262AsnThr: 1.262 ± 0.029	2.056AsnVal: 2.056 ± 0.032	0.395AsnTrp: 0.395 ± 0.013	0.604AsnTyr: 0.604 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	7.857ProAla: 7.857 ± 0.073	0.327ProCys: 0.327 ± 0.013	4.042ProAsp: 4.042 ± 0.053	3.147ProGlu: 3.147 ± 0.042	1.964ProPhe: 1.964 ± 0.027	5.469ProGly: 5.469 ± 0.054	1.17ProHis: 1.17 ± 0.021	2.208ProIle: 2.208 ± 0.032	1.143ProLys: 1.143 ± 0.027	5.097ProLeu: 5.097 ± 0.043	1.211ProMet: 1.211 ± 0.023	1.256ProAsn: 1.256 ± 0.027	3.49ProPro: 3.49 ± 0.062	1.702ProGln: 1.702 ± 0.029	3.997ProArg: 3.997 ± 0.046	3.444ProSer: 3.444 ± 0.046	3.341ProThr: 3.341 ± 0.049	4.796ProVal: 4.796 ± 0.05	0.881ProTrp: 0.881 ± 0.023	1.207ProTyr: 1.207 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	4.456GlnAla: 4.456 ± 0.055	0.213GlnCys: 0.213 ± 0.01	1.472GlnAsp: 1.472 ± 0.027	1.427GlnGlu: 1.427 ± 0.027	1.166GlnPhe: 1.166 ± 0.027	2.522GlnGly: 2.522 ± 0.037	0.762GlnHis: 0.762 ± 0.018	1.326GlnIle: 1.326 ± 0.026	0.77GlnLys: 0.77 ± 0.019	3.237GlnLeu: 3.237 ± 0.044	0.755GlnMet: 0.755 ± 0.02	0.616GlnAsn: 0.616 ± 0.021	2.115GlnPro: 2.115 ± 0.032	1.445GlnGln: 1.445 ± 0.035	2.957GlnArg: 2.957 ± 0.039	1.615GlnSer: 1.615 ± 0.029	1.663GlnThr: 1.663 ± 0.028	2.959GlnVal: 2.959 ± 0.043	0.536GlnTrp: 0.536 ± 0.016	0.735GlnTyr: 0.735 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	9.566ArgAla: 9.566 ± 0.086	0.552ArgCys: 0.552 ± 0.017	4.672ArgAsp: 4.672 ± 0.05	4.509ArgGlu: 4.509 ± 0.06	3.004ArgPhe: 3.004 ± 0.037	5.676ArgGly: 5.676 ± 0.049	2.043ArgHis: 2.043 ± 0.033	3.601ArgIle: 3.601 ± 0.043	1.751ArgLys: 1.751 ± 0.033	9.033ArgLeu: 9.033 ± 0.071	1.989ArgMet: 1.989 ± 0.029	1.735ArgAsn: 1.735 ± 0.031	4.418ArgPro: 4.418 ± 0.051	3.142ArgGln: 3.142 ± 0.034	7.416ArgArg: 7.416 ± 0.074	4.112ArgSer: 4.112 ± 0.046	4.786ArgThr: 4.786 ± 0.052	6.847ArgVal: 6.847 ± 0.063	1.43ArgTrp: 1.43 ± 0.027	2.008ArgTyr: 2.008 ± 0.03	0.0ArgXaa: 0.0 ± 0.0
Ser	6.476SerAla: 6.476 ± 0.054	0.395SerCys: 0.395 ± 0.013	2.75SerAsp: 2.75 ± 0.037	2.313SerGlu: 2.313 ± 0.032	1.853SerPhe: 1.853 ± 0.032	5.336SerGly: 5.336 ± 0.052	1.14SerHis: 1.14 ± 0.023	2.16SerIle: 2.16 ± 0.038	1.055SerLys: 1.055 ± 0.025	5.507SerLeu: 5.507 ± 0.06	1.164SerMet: 1.164 ± 0.024	1.245SerAsn: 1.245 ± 0.027	3.558SerPro: 3.558 ± 0.039	1.542SerGln: 1.542 ± 0.03	4.537SerArg: 4.537 ± 0.049	3.234SerSer: 3.234 ± 0.038	3.365SerThr: 3.365 ± 0.036	4.256SerVal: 4.256 ± 0.044	0.844SerTrp: 0.844 ± 0.021	1.207SerTyr: 1.207 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	7.102ThrAla: 7.102 ± 0.064	0.47ThrCys: 0.47 ± 0.017	2.956ThrAsp: 2.956 ± 0.041	2.336ThrGlu: 2.336 ± 0.039	2.357ThrPhe: 2.357 ± 0.035	5.634ThrGly: 5.634 ± 0.053	1.3ThrHis: 1.3 ± 0.023	2.652ThrIle: 2.652 ± 0.034	1.125ThrLys: 1.125 ± 0.024	6.404ThrLeu: 6.404 ± 0.055	1.26ThrMet: 1.26 ± 0.025	1.406ThrAsn: 1.406 ± 0.031	4.352ThrPro: 4.352 ± 0.052	1.653ThrGln: 1.653 ± 0.029	4.727ThrArg: 4.727 ± 0.044	3.502ThrSer: 3.502 ± 0.041	3.848ThrThr: 3.848 ± 0.052	5.047ThrVal: 5.047 ± 0.057	1.061ThrTrp: 1.061 ± 0.024	1.423ThrTyr: 1.423 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	10.647ValAla: 10.647 ± 0.073	0.671ValCys: 0.671 ± 0.02	4.95ValAsp: 4.95 ± 0.048	4.363ValGlu: 4.363 ± 0.053	2.676ValPhe: 2.676 ± 0.039	6.372ValGly: 6.372 ± 0.062	1.787ValHis: 1.787 ± 0.027	3.512ValIle: 3.512 ± 0.044	1.872ValLys: 1.872 ± 0.036	8.81ValLeu: 8.81 ± 0.082	1.696ValMet: 1.696 ± 0.028	2.014ValAsn: 2.014 ± 0.039	5.049ValPro: 5.049 ± 0.048	2.578ValGln: 2.578 ± 0.039	6.904ValArg: 6.904 ± 0.069	4.967ValSer: 4.967 ± 0.053	5.609ValThr: 5.609 ± 0.063	7.663ValVal: 7.663 ± 0.084	1.105ValTrp: 1.105 ± 0.024	1.713ValTyr: 1.713 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.423TrpAla: 1.423 ± 0.025	0.127TrpCys: 0.127 ± 0.008	0.757TrpAsp: 0.757 ± 0.021	0.565TrpGlu: 0.565 ± 0.017	0.597TrpPhe: 0.597 ± 0.016	1.04TrpGly: 1.04 ± 0.022	0.417TrpHis: 0.417 ± 0.013	0.645TrpIle: 0.645 ± 0.018	0.423TrpLys: 0.423 ± 0.017	1.818TrpLeu: 1.818 ± 0.035	0.391TrpMet: 0.391 ± 0.014	0.453TrpAsn: 0.453 ± 0.015	0.87TrpPro: 0.87 ± 0.023	0.692TrpGln: 0.692 ± 0.018	1.481TrpArg: 1.481 ± 0.027	0.957TrpSer: 0.957 ± 0.021	1.035TrpThr: 1.035 ± 0.026	1.065TrpVal: 1.065 ± 0.025	0.313TrpTrp: 0.313 ± 0.013	0.359TrpTyr: 0.359 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.54TyrAla: 2.54 ± 0.035	0.196TyrCys: 0.196 ± 0.01	1.43TyrAsp: 1.43 ± 0.028	1.219TyrGlu: 1.219 ± 0.026	0.954TyrPhe: 0.954 ± 0.021	2.036TyrGly: 2.036 ± 0.032	0.475TyrHis: 0.475 ± 0.016	0.684TyrIle: 0.684 ± 0.018	0.482TyrLys: 0.482 ± 0.015	2.304TyrLeu: 2.304 ± 0.036	0.389TyrMet: 0.389 ± 0.012	0.559TyrAsn: 0.559 ± 0.018	1.146TyrPro: 1.146 ± 0.022	0.772TyrGln: 0.772 ± 0.02	2.034TyrArg: 2.034 ± 0.034	1.104TyrSer: 1.104 ± 0.021	1.232TyrThr: 1.232 ± 0.025	1.923TyrVal: 1.923 ± 0.027	0.358TyrTrp: 0.358 ± 0.014	0.644TyrTyr: 0.644 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6189 proteins (2193066 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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