Amino acid dipepetide frequency for Granulosicoccus antarcticus IMCC3135

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.938AlaAla: 10.938 ± 0.101	1.192AlaCys: 1.192 ± 0.029	6.151AlaAsp: 6.151 ± 0.134	5.974AlaGlu: 5.974 ± 0.065	3.571AlaPhe: 3.571 ± 0.043	8.164AlaGly: 8.164 ± 0.074	1.907AlaHis: 1.907 ± 0.032	5.852AlaIle: 5.852 ± 0.064	3.01AlaLys: 3.01 ± 0.05	11.149AlaLeu: 11.149 ± 0.087	2.959AlaMet: 2.959 ± 0.043	3.193AlaAsn: 3.193 ± 0.045	3.69AlaPro: 3.69 ± 0.051	3.868AlaGln: 3.868 ± 0.047	5.708AlaArg: 5.708 ± 0.061	6.939AlaSer: 6.939 ± 0.065	5.455AlaThr: 5.455 ± 0.08	7.084AlaVal: 7.084 ± 0.072	1.188AlaTrp: 1.188 ± 0.025	2.243AlaTyr: 2.243 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	0.921CysAla: 0.921 ± 0.018	0.152CysCys: 0.152 ± 0.009	0.615CysAsp: 0.615 ± 0.016	0.591CysGlu: 0.591 ± 0.018	0.368CysPhe: 0.368 ± 0.013	0.905CysGly: 0.905 ± 0.022	0.302CysHis: 0.302 ± 0.012	0.572CysIle: 0.572 ± 0.019	0.32CysLys: 0.32 ± 0.012	1.126CysLeu: 1.126 ± 0.025	0.238CysMet: 0.238 ± 0.01	0.355CysAsn: 0.355 ± 0.012	0.438CysPro: 0.438 ± 0.017	0.409CysGln: 0.409 ± 0.013	0.57CysArg: 0.57 ± 0.019	0.746CysSer: 0.746 ± 0.019	0.569CysThr: 0.569 ± 0.021	0.747CysVal: 0.747 ± 0.019	0.143CysTrp: 0.143 ± 0.009	0.259CysTyr: 0.259 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.176AspAla: 6.176 ± 0.139	0.574AspCys: 0.574 ± 0.017	3.738AspAsp: 3.738 ± 0.087	3.996AspGlu: 3.996 ± 0.045	2.245AspPhe: 2.245 ± 0.037	5.094AspGly: 5.094 ± 0.275	1.129AspHis: 1.129 ± 0.022	3.591AspIle: 3.591 ± 0.047	2.193AspLys: 2.193 ± 0.038	5.33AspLeu: 5.33 ± 0.066	1.462AspMet: 1.462 ± 0.027	2.334AspAsn: 2.334 ± 0.09	2.718AspPro: 2.718 ± 0.04	2.123AspGln: 2.123 ± 0.033	3.09AspArg: 3.09 ± 0.038	4.346AspSer: 4.346 ± 0.167	3.675AspThr: 3.675 ± 0.124	4.345AspVal: 4.345 ± 0.059	0.92AspTrp: 0.92 ± 0.021	1.78AspTyr: 1.78 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	5.995GluAla: 5.995 ± 0.072	0.452GluCys: 0.452 ± 0.017	2.663GluAsp: 2.663 ± 0.038	3.187GluGlu: 3.187 ± 0.053	2.069GluPhe: 2.069 ± 0.037	3.772GluGly: 3.772 ± 0.047	1.514GluHis: 1.514 ± 0.03	3.131GluIle: 3.131 ± 0.04	2.287GluLys: 2.287 ± 0.043	6.81GluLeu: 6.81 ± 0.084	1.371GluMet: 1.371 ± 0.027	2.206GluAsn: 2.206 ± 0.033	2.672GluPro: 2.672 ± 0.044	3.234GluGln: 3.234 ± 0.044	3.874GluArg: 3.874 ± 0.05	4.113GluSer: 4.113 ± 0.045	3.247GluThr: 3.247 ± 0.045	3.888GluVal: 3.888 ± 0.054	0.74GluTrp: 0.74 ± 0.02	1.387GluTyr: 1.387 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	3.519PheAla: 3.519 ± 0.04	0.456PheCys: 0.456 ± 0.014	2.759PheAsp: 2.759 ± 0.044	2.215PheGlu: 2.215 ± 0.034	1.406PhePhe: 1.406 ± 0.029	3.134PheGly: 3.134 ± 0.046	0.77PheHis: 0.77 ± 0.019	2.07PheIle: 2.07 ± 0.033	1.257PheLys: 1.257 ± 0.024	3.365PheLeu: 3.365 ± 0.046	0.945PheMet: 0.945 ± 0.02	1.444PheAsn: 1.444 ± 0.027	1.473PhePro: 1.473 ± 0.03	1.158PheGln: 1.158 ± 0.024	1.826PheArg: 1.826 ± 0.031	2.892PheSer: 2.892 ± 0.041	2.195PheThr: 2.195 ± 0.051	2.655PheVal: 2.655 ± 0.036	0.511PheTrp: 0.511 ± 0.016	0.992PheTyr: 0.992 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	6.669GlyAla: 6.669 ± 0.075	0.921GlyCys: 0.921 ± 0.027	4.354GlyAsp: 4.354 ± 0.12	4.398GlyGlu: 4.398 ± 0.052	3.263GlyPhe: 3.263 ± 0.042	5.739GlyGly: 5.739 ± 0.068	1.651GlyHis: 1.651 ± 0.027	4.897GlyIle: 4.897 ± 0.102	3.219GlyLys: 3.219 ± 0.048	7.792GlyLeu: 7.792 ± 0.064	2.2GlyMet: 2.2 ± 0.034	2.7GlyAsn: 2.7 ± 0.049	2.406GlyPro: 2.406 ± 0.034	2.929GlyGln: 2.929 ± 0.04	3.954GlyArg: 3.954 ± 0.049	5.282GlySer: 5.282 ± 0.058	4.425GlyThr: 4.425 ± 0.086	5.74GlyVal: 5.74 ± 0.072	1.12GlyTrp: 1.12 ± 0.026	2.356GlyTyr: 2.356 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	2.097HisAla: 2.097 ± 0.034	0.325HisCys: 0.325 ± 0.013	1.324HisAsp: 1.324 ± 0.026	1.283HisGlu: 1.283 ± 0.023	0.859HisPhe: 0.859 ± 0.02	1.675HisGly: 1.675 ± 0.032	0.554HisHis: 0.554 ± 0.018	1.092HisIle: 1.092 ± 0.023	0.66HisLys: 0.66 ± 0.017	2.12HisLeu: 2.12 ± 0.032	0.511HisMet: 0.511 ± 0.016	0.584HisAsn: 0.584 ± 0.015	1.136HisPro: 1.136 ± 0.021	0.864HisGln: 0.864 ± 0.022	1.309HisArg: 1.309 ± 0.026	1.383HisSer: 1.383 ± 0.032	1.095HisThr: 1.095 ± 0.026	1.402HisVal: 1.402 ± 0.026	0.405HisTrp: 0.405 ± 0.014	0.692HisTyr: 0.692 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.311IleAla: 6.311 ± 0.063	0.609IleCys: 0.609 ± 0.017	4.221IleAsp: 4.221 ± 0.064	3.903IleGlu: 3.903 ± 0.049	1.801IlePhe: 1.801 ± 0.031	4.625IleGly: 4.625 ± 0.056	1.073IleHis: 1.073 ± 0.023	2.934IleIle: 2.934 ± 0.04	1.936IleLys: 1.936 ± 0.033	4.819IleLeu: 4.819 ± 0.055	1.172IleMet: 1.172 ± 0.024	2.25IleAsn: 2.25 ± 0.034	2.644IlePro: 2.644 ± 0.046	1.748IleGln: 1.748 ± 0.031	3.112IleArg: 3.112 ± 0.041	4.099IleSer: 4.099 ± 0.05	3.217IleThr: 3.217 ± 0.068	4.351IleVal: 4.351 ± 0.05	0.651IleTrp: 0.651 ± 0.019	1.299IleTyr: 1.299 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.486LysAla: 3.486 ± 0.058	0.229LysCys: 0.229 ± 0.01	1.646LysAsp: 1.646 ± 0.029	1.755LysGlu: 1.755 ± 0.036	0.976LysPhe: 0.976 ± 0.026	2.295LysGly: 2.295 ± 0.038	0.782LysHis: 0.782 ± 0.018	1.833LysIle: 1.833 ± 0.035	1.425LysLys: 1.425 ± 0.042	3.645LysLeu: 3.645 ± 0.053	0.807LysMet: 0.807 ± 0.02	1.22LysAsn: 1.22 ± 0.026	1.936LysPro: 1.936 ± 0.035	1.589LysGln: 1.589 ± 0.027	2.272LysArg: 2.272 ± 0.038	2.429LysSer: 2.429 ± 0.041	2.005LysThr: 2.005 ± 0.036	2.323LysVal: 2.323 ± 0.036	0.345LysTrp: 0.345 ± 0.012	0.762LysTyr: 0.762 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	11.06LeuAla: 11.06 ± 0.092	1.168LeuCys: 1.168 ± 0.027	6.406LeuAsp: 6.406 ± 0.081	5.929LeuGlu: 5.929 ± 0.061	3.851LeuPhe: 3.851 ± 0.05	7.594LeuGly: 7.594 ± 0.071	2.162LeuHis: 2.162 ± 0.035	5.89LeuIle: 5.89 ± 0.066	3.554LeuLys: 3.554 ± 0.047	11.177LeuLeu: 11.177 ± 0.115	2.595LeuMet: 2.595 ± 0.037	3.537LeuAsn: 3.537 ± 0.048	5.319LeuPro: 5.319 ± 0.054	4.166LeuGln: 4.166 ± 0.054	5.663LeuArg: 5.663 ± 0.068	8.363LeuSer: 8.363 ± 0.066	5.686LeuThr: 5.686 ± 0.056	7.35LeuVal: 7.35 ± 0.064	1.194LeuTrp: 1.194 ± 0.023	2.366LeuTyr: 2.366 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.617MetAla: 2.617 ± 0.039	0.187MetCys: 0.187 ± 0.009	1.287MetAsp: 1.287 ± 0.023	1.195MetGlu: 1.195 ± 0.026	0.762MetPhe: 0.762 ± 0.019	1.789MetGly: 1.789 ± 0.032	0.542MetHis: 0.542 ± 0.016	1.455MetIle: 1.455 ± 0.028	1.083MetLys: 1.083 ± 0.024	2.645MetLeu: 2.645 ± 0.04	0.669MetMet: 0.669 ± 0.018	1.084MetAsn: 1.084 ± 0.026	1.334MetPro: 1.334 ± 0.028	1.181MetGln: 1.181 ± 0.024	1.472MetArg: 1.472 ± 0.026	2.074MetSer: 2.074 ± 0.034	1.612MetThr: 1.612 ± 0.031	1.708MetVal: 1.708 ± 0.032	0.186MetTrp: 0.186 ± 0.009	0.397MetTyr: 0.397 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.449AsnAla: 3.449 ± 0.043	0.343AsnCys: 0.343 ± 0.013	2.317AsnAsp: 2.317 ± 0.111	2.007AsnGlu: 2.007 ± 0.029	1.165AsnPhe: 1.165 ± 0.023	2.874AsnGly: 2.874 ± 0.051	0.721AsnHis: 0.721 ± 0.016	1.889AsnIle: 1.889 ± 0.031	1.112AsnLys: 1.112 ± 0.026	3.172AsnLeu: 3.172 ± 0.04	0.779AsnMet: 0.779 ± 0.02	1.325AsnAsn: 1.325 ± 0.045	2.0AsnPro: 2.0 ± 0.032	1.299AsnGln: 1.299 ± 0.024	2.02AsnArg: 2.02 ± 0.032	2.346AsnSer: 2.346 ± 0.043	2.146AsnThr: 2.146 ± 0.05	2.259AsnVal: 2.259 ± 0.031	0.5AsnTrp: 0.5 ± 0.015	0.976AsnTyr: 0.976 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	4.576ProAla: 4.576 ± 0.057	0.327ProCys: 0.327 ± 0.013	3.511ProAsp: 3.511 ± 0.072	3.422ProGlu: 3.422 ± 0.056	1.73ProPhe: 1.73 ± 0.026	3.599ProGly: 3.599 ± 0.047	0.848ProHis: 0.848 ± 0.02	2.28ProIle: 2.28 ± 0.032	1.25ProLys: 1.25 ± 0.029	4.45ProLeu: 4.45 ± 0.048	1.173ProMet: 1.173 ± 0.024	1.255ProAsn: 1.255 ± 0.03	1.702ProPro: 1.702 ± 0.032	1.486ProGln: 1.486 ± 0.028	1.946ProArg: 1.946 ± 0.033	2.727ProSer: 2.727 ± 0.037	2.359ProThr: 2.359 ± 0.037	3.996ProVal: 3.996 ± 0.048	0.623ProTrp: 0.623 ± 0.016	1.081ProTyr: 1.081 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	4.377GlnAla: 4.377 ± 0.052	0.386GlnCys: 0.386 ± 0.014	1.804GlnAsp: 1.804 ± 0.03	1.917GlnGlu: 1.917 ± 0.03	1.447GlnPhe: 1.447 ± 0.023	2.628GlnGly: 2.628 ± 0.04	0.968GlnHis: 0.968 ± 0.022	2.301GlnIle: 2.301 ± 0.036	1.289GlnLys: 1.289 ± 0.025	4.59GlnLeu: 4.59 ± 0.049	0.993GlnMet: 0.993 ± 0.021	1.274GlnAsn: 1.274 ± 0.027	1.753GlnPro: 1.753 ± 0.03	2.131GlnGln: 2.131 ± 0.041	2.724GlnArg: 2.724 ± 0.042	2.989GlnSer: 2.989 ± 0.038	2.187GlnThr: 2.187 ± 0.034	2.782GlnVal: 2.782 ± 0.036	0.631GlnTrp: 0.631 ± 0.02	0.963GlnTyr: 0.963 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	4.892ArgAla: 4.892 ± 0.056	0.587ArgCys: 0.587 ± 0.017	3.114ArgAsp: 3.114 ± 0.038	3.396ArgGlu: 3.396 ± 0.053	2.44ArgPhe: 2.44 ± 0.036	3.382ArgGly: 3.382 ± 0.049	1.467ArgHis: 1.467 ± 0.03	3.552ArgIle: 3.552 ± 0.038	2.207ArgLys: 2.207 ± 0.044	6.378ArgLeu: 6.378 ± 0.077	1.525ArgMet: 1.525 ± 0.028	1.848ArgAsn: 1.848 ± 0.03	2.181ArgPro: 2.181 ± 0.038	2.821ArgGln: 2.821 ± 0.044	3.606ArgArg: 3.606 ± 0.055	3.648ArgSer: 3.648 ± 0.048	2.913ArgThr: 2.913 ± 0.038	4.018ArgVal: 4.018 ± 0.052	0.892ArgTrp: 0.892 ± 0.021	1.782ArgTyr: 1.782 ± 0.028	0.0ArgXaa: 0.0 ± 0.0
Ser	6.885SerAla: 6.885 ± 0.07	0.727SerCys: 0.727 ± 0.022	4.533SerAsp: 4.533 ± 0.135	4.061SerGlu: 4.061 ± 0.045	2.671SerPhe: 2.671 ± 0.042	6.094SerGly: 6.094 ± 0.062	1.442SerHis: 1.442 ± 0.031	4.126SerIle: 4.126 ± 0.046	2.099SerLys: 2.099 ± 0.039	7.645SerLeu: 7.645 ± 0.067	1.942SerMet: 1.942 ± 0.032	2.484SerAsn: 2.484 ± 0.053	2.843SerPro: 2.843 ± 0.037	2.571SerGln: 2.571 ± 0.038	3.891SerArg: 3.891 ± 0.051	5.205SerSer: 5.205 ± 0.085	4.137SerThr: 4.137 ± 0.079	5.414SerVal: 5.414 ± 0.06	0.934SerTrp: 0.934 ± 0.022	1.767SerTyr: 1.767 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	5.614ThrAla: 5.614 ± 0.074	0.46ThrCys: 0.46 ± 0.015	3.729ThrAsp: 3.729 ± 0.152	2.982ThrGlu: 2.982 ± 0.04	1.936ThrPhe: 1.936 ± 0.036	4.923ThrGly: 4.923 ± 0.075	1.266ThrHis: 1.266 ± 0.028	3.272ThrIle: 3.272 ± 0.07	1.257ThrLys: 1.257 ± 0.026	6.787ThrLeu: 6.787 ± 0.076	1.15ThrMet: 1.15 ± 0.023	1.658ThrAsn: 1.658 ± 0.041	3.045ThrPro: 3.045 ± 0.044	2.085ThrGln: 2.085 ± 0.033	3.127ThrArg: 3.127 ± 0.044	3.719ThrSer: 3.719 ± 0.054	3.27ThrThr: 3.27 ± 0.067	4.438ThrVal: 4.438 ± 0.073	0.635ThrTrp: 0.635 ± 0.018	1.208ThrTyr: 1.208 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	7.36ValAla: 7.36 ± 0.074	0.782ValCys: 0.782 ± 0.019	4.616ValAsp: 4.616 ± 0.067	4.411ValGlu: 4.411 ± 0.05	2.871ValPhe: 2.871 ± 0.041	5.033ValGly: 5.033 ± 0.07	1.394ValHis: 1.394 ± 0.028	4.196ValIle: 4.196 ± 0.046	2.329ValLys: 2.329 ± 0.035	7.539ValLeu: 7.539 ± 0.076	1.924ValMet: 1.924 ± 0.034	2.672ValAsn: 2.672 ± 0.06	3.244ValPro: 3.244 ± 0.043	2.513ValGln: 2.513 ± 0.04	3.852ValArg: 3.852 ± 0.055	5.478ValSer: 5.478 ± 0.055	4.265ValThr: 4.265 ± 0.08	5.733ValVal: 5.733 ± 0.059	0.804ValTrp: 0.804 ± 0.019	1.695ValTyr: 1.695 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	0.991TrpAla: 0.991 ± 0.024	0.15TrpCys: 0.15 ± 0.008	0.605TrpAsp: 0.605 ± 0.019	0.604TrpGlu: 0.604 ± 0.016	0.576TrpPhe: 0.576 ± 0.017	0.758TrpGly: 0.758 ± 0.019	0.342TrpHis: 0.342 ± 0.014	0.699TrpIle: 0.699 ± 0.016	0.455TrpLys: 0.455 ± 0.014	1.702TrpLeu: 1.702 ± 0.027	0.386TrpMet: 0.386 ± 0.013	0.514TrpAsn: 0.514 ± 0.014	0.606TrpPro: 0.606 ± 0.017	0.818TrpGln: 0.818 ± 0.023	0.849TrpArg: 0.849 ± 0.024	0.919TrpSer: 0.919 ± 0.023	0.664TrpThr: 0.664 ± 0.019	0.848TrpVal: 0.848 ± 0.019	0.217TrpTrp: 0.217 ± 0.011	0.339TrpTyr: 0.339 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.306TyrAla: 2.306 ± 0.032	0.318TyrCys: 0.318 ± 0.012	1.465TyrAsp: 1.465 ± 0.028	1.393TyrGlu: 1.393 ± 0.027	1.035TyrPhe: 1.035 ± 0.025	1.939TyrGly: 1.939 ± 0.03	0.539TyrHis: 0.539 ± 0.015	1.144TyrIle: 1.144 ± 0.023	0.816TyrLys: 0.816 ± 0.022	2.789TyrLeu: 2.789 ± 0.039	0.478TyrMet: 0.478 ± 0.017	0.756TyrAsn: 0.756 ± 0.019	1.201TyrPro: 1.201 ± 0.025	1.142TyrGln: 1.142 ± 0.028	1.784TyrArg: 1.784 ± 0.029	1.771TyrSer: 1.771 ± 0.034	1.438TyrThr: 1.438 ± 0.035	1.627TyrVal: 1.627 ± 0.027	0.406TyrTrp: 0.406 ± 0.015	0.724TyrTyr: 0.724 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6680 proteins (2309472 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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