Cutibacterium acnes JCM 18916

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinomycetia; Propionibacteriales; Propionibacteriaceae; Cutibacterium; Cutibacterium acnes

Average proteome isoelectric point is 6.71

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3663 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|W4TVT2|W4TVT2_CUTAC AsnC-family transcriptional regulatory protein OS=Cutibacterium acnes JCM 18916 OX=1302242 GN=JCM18916_2317 PE=4 SV=1
MM1 pKa = 7.06MVDD4 pKa = 4.39GKK6 pKa = 10.34GTLCCHH12 pKa = 7.08FGGDD16 pKa = 3.35TGGQGGCVGCAEE28 pKa = 4.52SSLDD32 pKa = 3.49EE33 pKa = 4.83CSDD36 pKa = 3.36DD37 pKa = 4.24RR38 pKa = 11.84AAQFQVVDD46 pKa = 4.22DD47 pKa = 4.56GFAAVLADD55 pKa = 3.95LCRR58 pKa = 11.84GAGLKK63 pKa = 10.11AADD66 pKa = 3.25WVMEE70 pKa = 4.13LFPLEE75 pKa = 3.79AAFAGGGDD83 pKa = 3.61SS84 pKa = 4.2

Molecular weight: 8.45 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|W4TWA7|W4TWA7_CUTAC Ribose ABC transport system OS=Cutibacterium acnes JCM 18916 OX=1302242 GN=JCM18916_2493 PE=4 SV=1
MM1 pKa = 7.45KK2 pKa = 9.61RR3 pKa = 11.84TFQPSNRR10 pKa = 11.84RR11 pKa = 11.84RR12 pKa = 11.84ARR14 pKa = 11.84NHH16 pKa = 5.31GFRR19 pKa = 11.84SRR21 pKa = 11.84MSTRR25 pKa = 11.84AGRR28 pKa = 11.84SILAARR34 pKa = 11.84RR35 pKa = 11.84RR36 pKa = 11.84KK37 pKa = 10.31GRR39 pKa = 11.84VNLSAA44 pKa = 4.92

Molecular weight: 5.17 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3663

0

3663

696179

37

1246

190.1

20.62

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

10.785 ± 0.051

1.274 ± 0.015

5.984 ± 0.045

4.994 ± 0.041

2.862 ± 0.032

8.36 ± 0.04

2.517 ± 0.023

4.833 ± 0.03

2.835 ± 0.039

9.239 ± 0.046

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.652 ± 0.022

2.441 ± 0.022

5.611 ± 0.034

2.973 ± 0.024

7.297 ± 0.049

6.69 ± 0.038

6.427 ± 0.037

8.612 ± 0.046

1.721 ± 0.025

1.893 ± 0.022
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski