Amino acid dipepetide frequency for Wallal virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.335AlaAla: 5.335 ± 1.402
0.485AlaCys: 0.485 ± 0.323
2.102AlaAsp: 2.102 ± 0.72
4.204AlaGlu: 4.204 ± 0.673
1.293AlaPhe: 1.293 ± 0.428
2.91AlaGly: 2.91 ± 0.504
1.293AlaHis: 1.293 ± 0.54
4.689AlaIle: 4.689 ± 1.075
3.557AlaLys: 3.557 ± 0.824
6.791AlaLeu: 6.791 ± 1.318
2.102AlaMet: 2.102 ± 0.658
3.072AlaAsn: 3.072 ± 0.84
2.102AlaPro: 2.102 ± 0.402
2.91AlaGln: 2.91 ± 0.842
4.365AlaArg: 4.365 ± 0.981
3.234AlaSer: 3.234 ± 0.396
3.234AlaThr: 3.234 ± 0.944
4.85AlaVal: 4.85 ± 1.139
0.97AlaTrp: 0.97 ± 0.258
2.91AlaTyr: 2.91 ± 1.1
0.0AlaXaa: 0.0 ± 0.0
Cys
0.485CysAla: 0.485 ± 0.203
0.162CysCys: 0.162 ± 0.137
0.97CysAsp: 0.97 ± 0.415
0.647CysGlu: 0.647 ± 0.257
0.485CysPhe: 0.485 ± 0.323
1.293CysGly: 1.293 ± 0.374
0.162CysHis: 0.162 ± 0.137
0.647CysIle: 0.647 ± 0.22
0.162CysLys: 0.162 ± 0.129
0.808CysLeu: 0.808 ± 0.44
0.485CysMet: 0.485 ± 0.287
0.485CysAsn: 0.485 ± 0.28
0.808CysPro: 0.808 ± 0.437
0.162CysGln: 0.162 ± 0.158
0.647CysArg: 0.647 ± 0.4
0.647CysSer: 0.647 ± 0.344
0.162CysThr: 0.162 ± 0.129
1.132CysVal: 1.132 ± 0.462
0.0CysTrp: 0.0 ± 0.0
0.647CysTyr: 0.647 ± 0.416
0.0CysXaa: 0.0 ± 0.0
Asp
3.719AspAla: 3.719 ± 0.489
0.485AspCys: 0.485 ± 0.284
4.689AspAsp: 4.689 ± 0.779
5.012AspGlu: 5.012 ± 1.047
3.072AspPhe: 3.072 ± 0.567
3.395AspGly: 3.395 ± 0.609
0.808AspHis: 0.808 ± 0.388
2.91AspIle: 2.91 ± 0.764
2.102AspLys: 2.102 ± 0.429
3.719AspLeu: 3.719 ± 0.786
0.647AspMet: 0.647 ± 0.324
1.132AspAsn: 1.132 ± 0.245
2.587AspPro: 2.587 ± 0.862
3.557AspGln: 3.557 ± 0.968
3.719AspArg: 3.719 ± 0.644
2.264AspSer: 2.264 ± 0.408
2.91AspThr: 2.91 ± 0.759
7.599AspVal: 7.599 ± 0.968
0.97AspTrp: 0.97 ± 0.406
1.778AspTyr: 1.778 ± 0.385
0.0AspXaa: 0.0 ± 0.0
Glu
5.012GluAla: 5.012 ± 0.673
0.485GluCys: 0.485 ± 0.387
4.042GluAsp: 4.042 ± 0.535
8.731GluGlu: 8.731 ± 1.517
2.425GluPhe: 2.425 ± 0.546
4.204GluGly: 4.204 ± 0.885
0.808GluHis: 0.808 ± 0.43
5.335GluIle: 5.335 ± 1.123
5.335GluLys: 5.335 ± 0.845
7.599GluLeu: 7.599 ± 0.948
3.072GluMet: 3.072 ± 0.774
3.072GluAsn: 3.072 ± 0.626
2.264GluPro: 2.264 ± 0.428
2.425GluGln: 2.425 ± 0.566
4.527GluArg: 4.527 ± 0.792
4.365GluSer: 4.365 ± 0.78
2.91GluThr: 2.91 ± 0.431
5.335GluVal: 5.335 ± 1.021
1.293GluTrp: 1.293 ± 0.576
3.234GluTyr: 3.234 ± 0.615
0.0GluXaa: 0.0 ± 0.0
Phe
2.587PheAla: 2.587 ± 0.606
0.647PheCys: 0.647 ± 0.328
2.587PheAsp: 2.587 ± 0.705
2.425PheGlu: 2.425 ± 0.673
1.132PhePhe: 1.132 ± 0.437
2.425PheGly: 2.425 ± 0.484
1.132PheHis: 1.132 ± 0.322
3.395PheIle: 3.395 ± 0.462
1.617PheLys: 1.617 ± 0.502
3.072PheLeu: 3.072 ± 0.496
1.132PheMet: 1.132 ± 0.309
1.617PheAsn: 1.617 ± 0.446
1.94PhePro: 1.94 ± 0.496
1.455PheGln: 1.455 ± 0.48
2.587PheArg: 2.587 ± 0.799
2.749PheSer: 2.749 ± 0.65
1.293PheThr: 1.293 ± 0.355
1.455PheVal: 1.455 ± 0.35
0.647PheTrp: 0.647 ± 0.3
2.425PheTyr: 2.425 ± 0.573
0.0PheXaa: 0.0 ± 0.0
Gly
3.234GlyAla: 3.234 ± 0.733
0.485GlyCys: 0.485 ± 0.222
3.557GlyAsp: 3.557 ± 1.473
3.88GlyGlu: 3.88 ± 0.638
2.264GlyPhe: 2.264 ± 0.58
2.425GlyGly: 2.425 ± 0.709
1.132GlyHis: 1.132 ± 0.257
2.425GlyIle: 2.425 ± 0.613
5.174GlyLys: 5.174 ± 1.17
4.85GlyLeu: 4.85 ± 0.705
2.102GlyMet: 2.102 ± 0.699
2.749GlyAsn: 2.749 ± 0.884
2.102GlyPro: 2.102 ± 0.504
2.102GlyGln: 2.102 ± 0.578
3.234GlyArg: 3.234 ± 0.64
3.072GlySer: 3.072 ± 0.756
2.749GlyThr: 2.749 ± 0.343
3.88GlyVal: 3.88 ± 0.855
1.132GlyTrp: 1.132 ± 0.367
2.264GlyTyr: 2.264 ± 0.769
0.0GlyXaa: 0.0 ± 0.0
His
1.293HisAla: 1.293 ± 0.43
0.485HisCys: 0.485 ± 0.3
1.132HisAsp: 1.132 ± 0.197
1.778HisGlu: 1.778 ± 0.48
0.808HisPhe: 0.808 ± 0.266
0.647HisGly: 0.647 ± 0.379
0.162HisHis: 0.162 ± 0.133
1.132HisIle: 1.132 ± 0.26
1.617HisLys: 1.617 ± 0.392
3.072HisLeu: 3.072 ± 0.744
0.647HisMet: 0.647 ± 0.206
0.97HisAsn: 0.97 ± 0.312
0.808HisPro: 0.808 ± 0.294
0.647HisGln: 0.647 ± 0.202
1.617HisArg: 1.617 ± 0.706
0.323HisSer: 0.323 ± 0.166
1.132HisThr: 1.132 ± 0.579
1.617HisVal: 1.617 ± 0.295
0.162HisTrp: 0.162 ± 0.158
0.647HisTyr: 0.647 ± 0.222
0.0HisXaa: 0.0 ± 0.0
Ile
4.527IleAla: 4.527 ± 0.814
0.647IleCys: 0.647 ± 0.409
5.174IleAsp: 5.174 ± 0.536
4.689IleGlu: 4.689 ± 0.629
2.587IlePhe: 2.587 ± 0.951
2.91IleGly: 2.91 ± 0.752
1.94IleHis: 1.94 ± 0.587
3.719IleIle: 3.719 ± 0.893
5.335IleLys: 5.335 ± 1.214
6.306IleLeu: 6.306 ± 0.671
2.425IleMet: 2.425 ± 0.719
3.395IleAsn: 3.395 ± 0.518
2.587IlePro: 2.587 ± 0.407
2.425IleGln: 2.425 ± 0.582
3.072IleArg: 3.072 ± 0.787
2.587IleSer: 2.587 ± 0.428
3.88IleThr: 3.88 ± 0.7
3.88IleVal: 3.88 ± 0.747
1.293IleTrp: 1.293 ± 0.415
2.425IleTyr: 2.425 ± 0.895
0.0IleXaa: 0.0 ± 0.0
Lys
2.749LysAla: 2.749 ± 0.564
0.808LysCys: 0.808 ± 0.356
3.88LysAsp: 3.88 ± 0.968
5.659LysGlu: 5.659 ± 2.121
2.749LysPhe: 2.749 ± 0.516
2.91LysGly: 2.91 ± 0.735
0.97LysHis: 0.97 ± 0.332
4.204LysIle: 4.204 ± 1.092
6.791LysLys: 6.791 ± 1.403
5.012LysLeu: 5.012 ± 1.234
3.395LysMet: 3.395 ± 0.858
3.234LysAsn: 3.234 ± 0.897
1.455LysPro: 1.455 ± 0.378
2.425LysGln: 2.425 ± 0.564
4.85LysArg: 4.85 ± 0.857
3.557LysSer: 3.557 ± 0.966
2.91LysThr: 2.91 ± 0.773
5.335LysVal: 5.335 ± 0.827
0.323LysTrp: 0.323 ± 0.22
2.102LysTyr: 2.102 ± 0.49
0.0LysXaa: 0.0 ± 0.0
Leu
6.144LeuAla: 6.144 ± 1.009
1.293LeuCys: 1.293 ± 0.44
4.85LeuAsp: 4.85 ± 0.797
5.335LeuGlu: 5.335 ± 0.881
2.587LeuPhe: 2.587 ± 0.485
3.557LeuGly: 3.557 ± 0.729
1.617LeuHis: 1.617 ± 0.571
4.85LeuIle: 4.85 ± 0.65
7.437LeuLys: 7.437 ± 1.472
6.144LeuLeu: 6.144 ± 1.017
3.719LeuMet: 3.719 ± 0.572
5.174LeuAsn: 5.174 ± 0.949
3.719LeuPro: 3.719 ± 0.838
3.395LeuGln: 3.395 ± 0.792
8.084LeuArg: 8.084 ± 1.016
5.174LeuSer: 5.174 ± 1.288
3.719LeuThr: 3.719 ± 0.865
6.144LeuVal: 6.144 ± 0.793
1.617LeuTrp: 1.617 ± 0.645
2.264LeuTyr: 2.264 ± 0.6
0.0LeuXaa: 0.0 ± 0.0
Met
2.91MetAla: 2.91 ± 0.442
0.808MetCys: 0.808 ± 0.523
1.778MetAsp: 1.778 ± 0.485
2.749MetGlu: 2.749 ± 0.518
1.293MetPhe: 1.293 ± 0.309
1.94MetGly: 1.94 ± 0.424
0.647MetHis: 0.647 ± 0.295
3.234MetIle: 3.234 ± 0.674
1.94MetLys: 1.94 ± 0.378
3.719MetLeu: 3.719 ± 0.517
1.455MetMet: 1.455 ± 0.643
1.293MetAsn: 1.293 ± 0.362
0.97MetPro: 0.97 ± 0.331
1.293MetGln: 1.293 ± 0.525
2.749MetArg: 2.749 ± 0.678
2.91MetSer: 2.91 ± 0.598
2.587MetThr: 2.587 ± 0.616
2.587MetVal: 2.587 ± 0.795
0.323MetTrp: 0.323 ± 0.188
0.485MetTyr: 0.485 ± 0.315
0.0MetXaa: 0.0 ± 0.0
Asn
2.264AsnAla: 2.264 ± 0.977
0.0AsnCys: 0.0 ± 0.0
3.234AsnAsp: 3.234 ± 0.537
4.527AsnGlu: 4.527 ± 0.494
1.617AsnPhe: 1.617 ± 0.434
3.234AsnGly: 3.234 ± 0.954
0.808AsnHis: 0.808 ± 0.314
3.719AsnIle: 3.719 ± 0.743
1.455AsnLys: 1.455 ± 0.386
4.365AsnLeu: 4.365 ± 0.626
1.778AsnMet: 1.778 ± 0.547
1.778AsnAsn: 1.778 ± 0.565
0.97AsnPro: 0.97 ± 0.314
1.94AsnGln: 1.94 ± 0.977
2.749AsnArg: 2.749 ± 0.286
3.072AsnSer: 3.072 ± 0.522
2.749AsnThr: 2.749 ± 0.757
4.204AsnVal: 4.204 ± 0.945
0.485AsnTrp: 0.485 ± 0.199
1.455AsnTyr: 1.455 ± 0.464
0.0AsnXaa: 0.0 ± 0.0
Pro
1.617ProAla: 1.617 ± 0.476
0.0ProCys: 0.0 ± 0.0
1.94ProAsp: 1.94 ± 0.422
3.072ProGlu: 3.072 ± 0.746
1.293ProPhe: 1.293 ± 0.48
1.778ProGly: 1.778 ± 0.649
0.647ProHis: 0.647 ± 0.227
3.395ProIle: 3.395 ± 0.415
1.94ProLys: 1.94 ± 0.736
2.587ProLeu: 2.587 ± 0.693
1.293ProMet: 1.293 ± 0.201
1.293ProAsn: 1.293 ± 0.43
2.425ProPro: 2.425 ± 0.92
0.97ProGln: 0.97 ± 0.479
2.425ProArg: 2.425 ± 0.569
2.425ProSer: 2.425 ± 0.566
3.395ProThr: 3.395 ± 1.091
1.94ProVal: 1.94 ± 0.422
1.132ProTrp: 1.132 ± 0.507
2.749ProTyr: 2.749 ± 0.616
0.0ProXaa: 0.0 ± 0.0
Gln
2.425GlnAla: 2.425 ± 0.637
0.323GlnCys: 0.323 ± 0.2
1.132GlnAsp: 1.132 ± 0.307
2.425GlnGlu: 2.425 ± 0.549
1.132GlnPhe: 1.132 ± 0.329
2.264GlnGly: 2.264 ± 0.526
1.132GlnHis: 1.132 ± 0.369
3.88GlnIle: 3.88 ± 1.171
1.617GlnLys: 1.617 ± 0.46
4.042GlnLeu: 4.042 ± 0.561
0.97GlnMet: 0.97 ± 0.144
2.264GlnAsn: 2.264 ± 0.758
1.455GlnPro: 1.455 ± 0.456
1.94GlnGln: 1.94 ± 0.746
2.102GlnArg: 2.102 ± 0.431
1.455GlnSer: 1.455 ± 0.499
2.749GlnThr: 2.749 ± 0.481
1.94GlnVal: 1.94 ± 0.703
0.0GlnTrp: 0.0 ± 0.0
1.617GlnTyr: 1.617 ± 0.274
0.0GlnXaa: 0.0 ± 0.0
Arg
4.042ArgAla: 4.042 ± 0.902
0.647ArgCys: 0.647 ± 0.219
3.719ArgAsp: 3.719 ± 0.84
4.85ArgGlu: 4.85 ± 0.954
3.88ArgPhe: 3.88 ± 1.119
3.072ArgGly: 3.072 ± 0.639
1.455ArgHis: 1.455 ± 0.459
5.821ArgIle: 5.821 ± 1.392
4.527ArgLys: 4.527 ± 1.099
4.365ArgLeu: 4.365 ± 0.806
2.425ArgMet: 2.425 ± 0.534
3.072ArgAsn: 3.072 ± 0.79
2.102ArgPro: 2.102 ± 0.636
1.293ArgGln: 1.293 ± 0.282
4.365ArgArg: 4.365 ± 0.648
3.719ArgSer: 3.719 ± 0.634
3.395ArgThr: 3.395 ± 0.712
5.982ArgVal: 5.982 ± 0.744
0.323ArgTrp: 0.323 ± 0.254
1.617ArgTyr: 1.617 ± 0.66
0.0ArgXaa: 0.0 ± 0.0
Ser
3.234SerAla: 3.234 ± 0.653
0.323SerCys: 0.323 ± 0.208
3.395SerAsp: 3.395 ± 0.468
4.527SerGlu: 4.527 ± 0.722
3.234SerPhe: 3.234 ± 0.642
3.88SerGly: 3.88 ± 1.037
1.455SerHis: 1.455 ± 0.43
3.88SerIle: 3.88 ± 0.641
3.557SerLys: 3.557 ± 0.904
4.85SerLeu: 4.85 ± 0.994
3.395SerMet: 3.395 ± 0.613
2.587SerAsn: 2.587 ± 0.67
2.264SerPro: 2.264 ± 0.531
1.778SerGln: 1.778 ± 0.476
2.425SerArg: 2.425 ± 0.628
2.425SerSer: 2.425 ± 0.583
2.91SerThr: 2.91 ± 0.707
3.072SerVal: 3.072 ± 0.633
1.293SerTrp: 1.293 ± 0.362
2.264SerTyr: 2.264 ± 0.575
0.0SerXaa: 0.0 ± 0.0
Thr
3.234ThrAla: 3.234 ± 1.136
0.485ThrCys: 0.485 ± 0.253
2.425ThrAsp: 2.425 ± 0.418
2.91ThrGlu: 2.91 ± 0.576
1.617ThrPhe: 1.617 ± 0.369
4.204ThrGly: 4.204 ± 1.064
1.132ThrHis: 1.132 ± 0.789
2.91ThrIle: 2.91 ± 0.734
4.365ThrLys: 4.365 ± 0.994
5.659ThrLeu: 5.659 ± 1.013
2.264ThrMet: 2.264 ± 0.48
1.94ThrAsn: 1.94 ± 0.589
2.749ThrPro: 2.749 ± 0.718
0.97ThrGln: 0.97 ± 0.276
1.94ThrArg: 1.94 ± 0.398
4.042ThrSer: 4.042 ± 0.772
3.395ThrThr: 3.395 ± 0.855
3.234ThrVal: 3.234 ± 0.713
0.808ThrTrp: 0.808 ± 0.428
2.91ThrTyr: 2.91 ± 0.782
0.0ThrXaa: 0.0 ± 0.0
Val
4.365ValAla: 4.365 ± 0.864
1.132ValCys: 1.132 ± 0.351
3.234ValAsp: 3.234 ± 0.53
4.85ValGlu: 4.85 ± 0.795
3.072ValPhe: 3.072 ± 0.548
3.719ValGly: 3.719 ± 0.422
1.94ValHis: 1.94 ± 0.762
2.91ValIle: 2.91 ± 0.449
4.042ValLys: 4.042 ± 0.665
6.306ValLeu: 6.306 ± 1.11
2.749ValMet: 2.749 ± 0.713
4.204ValAsn: 4.204 ± 0.652
4.204ValPro: 4.204 ± 0.829
3.395ValGln: 3.395 ± 1.051
5.982ValArg: 5.982 ± 0.811
5.497ValSer: 5.497 ± 0.919
3.395ValThr: 3.395 ± 0.916
4.365ValVal: 4.365 ± 0.896
0.485ValTrp: 0.485 ± 0.302
3.719ValTyr: 3.719 ± 0.548
0.0ValXaa: 0.0 ± 0.0
Trp
0.808TrpAla: 0.808 ± 0.366
0.323TrpCys: 0.323 ± 0.2
1.132TrpAsp: 1.132 ± 0.579
1.455TrpGlu: 1.455 ± 0.598
0.485TrpPhe: 0.485 ± 0.214
1.293TrpGly: 1.293 ± 0.482
0.97TrpHis: 0.97 ± 0.548
1.293TrpIle: 1.293 ± 0.335
0.97TrpLys: 0.97 ± 0.391
0.485TrpLeu: 0.485 ± 0.203
0.485TrpMet: 0.485 ± 0.337
0.808TrpAsn: 0.808 ± 0.418
0.0TrpPro: 0.0 ± 0.0
0.162TrpGln: 0.162 ± 0.185
0.647TrpArg: 0.647 ± 0.231
0.808TrpSer: 0.808 ± 0.367
0.485TrpThr: 0.485 ± 0.222
1.132TrpVal: 1.132 ± 0.404
0.162TrpTrp: 0.162 ± 0.149
0.162TrpTyr: 0.162 ± 0.137
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.425TyrAla: 2.425 ± 0.443
0.97TyrCys: 0.97 ± 0.339
2.102TyrAsp: 2.102 ± 0.615
2.749TyrGlu: 2.749 ± 0.723
1.293TyrPhe: 1.293 ± 0.455
2.749TyrGly: 2.749 ± 0.492
0.485TyrHis: 0.485 ± 0.184
1.455TyrIle: 1.455 ± 0.595
1.778TyrLys: 1.778 ± 0.351
3.234TyrLeu: 3.234 ± 0.609
0.97TyrMet: 0.97 ± 0.463
2.264TyrAsn: 2.264 ± 0.892
0.808TyrPro: 0.808 ± 0.218
1.617TyrGln: 1.617 ± 0.556
2.587TyrArg: 2.587 ± 0.326
2.425TyrSer: 2.425 ± 0.687
3.234TyrThr: 3.234 ± 0.691
3.88TyrVal: 3.88 ± 0.683
0.647TyrTrp: 0.647 ± 0.416
2.102TyrTyr: 2.102 ± 0.931
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (6186 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski