Amino acid dipepetide frequency for Colobus angolensis palliatus (Peters Angolan colobus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.346AlaAla: 6.346 ± 0.032	1.362AlaCys: 1.362 ± 0.011	2.903AlaAsp: 2.903 ± 0.012	4.708AlaGlu: 4.708 ± 0.022	2.606AlaPhe: 2.606 ± 0.014	4.529AlaGly: 4.529 ± 0.025	1.531AlaHis: 1.531 ± 0.009	2.8AlaIle: 2.8 ± 0.013	3.501AlaLys: 3.501 ± 0.021	6.918AlaLeu: 6.918 ± 0.028	1.489AlaMet: 1.489 ± 0.01	2.047AlaAsn: 2.047 ± 0.01	3.925AlaPro: 3.925 ± 0.025	3.221AlaGln: 3.221 ± 0.018	3.504AlaArg: 3.504 ± 0.017	5.653AlaSer: 5.653 ± 0.023	3.606AlaThr: 3.606 ± 0.016	4.644AlaVal: 4.644 ± 0.017	0.797AlaTrp: 0.797 ± 0.007	1.527AlaTyr: 1.527 ± 0.011	0.001AlaXaa: 0.001 ± 0.0
Cys	1.194CysAla: 1.194 ± 0.011	0.648CysCys: 0.648 ± 0.009	1.006CysAsp: 1.006 ± 0.01	1.311CysGlu: 1.311 ± 0.012	0.845CysPhe: 0.845 ± 0.007	1.713CysGly: 1.713 ± 0.015	0.68CysHis: 0.68 ± 0.006	0.975CysIle: 0.975 ± 0.008	1.189CysLys: 1.189 ± 0.011	2.187CysLeu: 2.187 ± 0.013	0.42CysMet: 0.42 ± 0.005	0.823CysAsn: 0.823 ± 0.008	1.35CysPro: 1.35 ± 0.013	1.077CysGln: 1.077 ± 0.011	1.281CysArg: 1.281 ± 0.01	2.002CysSer: 2.002 ± 0.014	1.098CysThr: 1.098 ± 0.009	1.308CysVal: 1.308 ± 0.01	0.296CysTrp: 0.296 ± 0.004	0.567CysTyr: 0.567 ± 0.005	0.0CysXaa: 0.0 ± 0.0
Asp	2.859AspAla: 2.859 ± 0.013	1.066AspCys: 1.066 ± 0.01	2.688AspAsp: 2.688 ± 0.015	3.498AspGlu: 3.498 ± 0.018	2.136AspPhe: 2.136 ± 0.012	3.333AspGly: 3.333 ± 0.023	1.152AspHis: 1.152 ± 0.008	2.657AspIle: 2.657 ± 0.013	2.595AspLys: 2.595 ± 0.014	5.032AspLeu: 5.032 ± 0.022	1.132AspMet: 1.132 ± 0.01	1.71AspAsn: 1.71 ± 0.011	2.891AspPro: 2.891 ± 0.014	1.849AspGln: 1.849 ± 0.011	2.416AspArg: 2.416 ± 0.014	4.221AspSer: 4.221 ± 0.016	2.498AspThr: 2.498 ± 0.013	3.106AspVal: 3.106 ± 0.015	0.632AspTrp: 0.632 ± 0.005	1.519AspTyr: 1.519 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	5.197GluAla: 5.197 ± 0.024	1.478GluCys: 1.478 ± 0.018	4.532GluAsp: 4.532 ± 0.018	8.042GluGlu: 8.042 ± 0.042	2.086GluPhe: 2.086 ± 0.01	4.19GluGly: 4.19 ± 0.017	1.53GluHis: 1.53 ± 0.009	3.257GluIle: 3.257 ± 0.019	5.553GluLys: 5.553 ± 0.031	6.524GluLeu: 6.524 ± 0.031	1.715GluMet: 1.715 ± 0.01	3.242GluAsn: 3.242 ± 0.017	3.218GluPro: 3.218 ± 0.024	3.168GluGln: 3.168 ± 0.02	3.996GluArg: 3.996 ± 0.022	4.425GluSer: 4.425 ± 0.019	3.46GluThr: 3.46 ± 0.015	4.245GluVal: 4.245 ± 0.019	0.709GluTrp: 0.709 ± 0.006	1.668GluTyr: 1.668 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	1.965PheAla: 1.965 ± 0.009	0.921PheCys: 0.921 ± 0.007	1.7PheAsp: 1.7 ± 0.01	2.054PheGlu: 2.054 ± 0.01	1.582PhePhe: 1.582 ± 0.01	2.206PheGly: 2.206 ± 0.013	1.059PheHis: 1.059 ± 0.009	1.824PheIle: 1.824 ± 0.014	1.838PheLys: 1.838 ± 0.011	4.017PheLeu: 4.017 ± 0.021	0.774PheMet: 0.774 ± 0.006	1.369PheAsn: 1.369 ± 0.01	2.001PhePro: 2.001 ± 0.012	1.821PheGln: 1.821 ± 0.01	2.001PheArg: 2.001 ± 0.014	3.413PheSer: 3.413 ± 0.018	2.069PheThr: 2.069 ± 0.012	2.136PheVal: 2.136 ± 0.011	0.491PheTrp: 0.491 ± 0.005	1.16PheTyr: 1.16 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	4.267GlyAla: 4.267 ± 0.022	1.249GlyCys: 1.249 ± 0.01	3.145GlyAsp: 3.145 ± 0.018	4.177GlyGlu: 4.177 ± 0.022	2.403GlyPhe: 2.403 ± 0.015	4.794GlyGly: 4.794 ± 0.03	1.685GlyHis: 1.685 ± 0.012	2.823GlyIle: 2.823 ± 0.016	3.927GlyLys: 3.927 ± 0.02	5.818GlyLeu: 5.818 ± 0.026	1.327GlyMet: 1.327 ± 0.01	2.373GlyAsn: 2.373 ± 0.012	4.085GlyPro: 4.085 ± 0.04	2.748GlyGln: 2.748 ± 0.015	3.646GlyArg: 3.646 ± 0.019	5.732GlySer: 5.732 ± 0.026	3.59GlyThr: 3.59 ± 0.014	3.551GlyVal: 3.551 ± 0.018	0.789GlyTrp: 0.789 ± 0.008	1.759GlyTyr: 1.759 ± 0.012	0.001GlyXaa: 0.001 ± 0.0
His	1.312HisAla: 1.312 ± 0.01	0.75HisCys: 0.75 ± 0.007	0.904HisAsp: 0.904 ± 0.007	1.348HisGlu: 1.348 ± 0.009	1.085HisPhe: 1.085 ± 0.007	1.525HisGly: 1.525 ± 0.01	0.909HisHis: 0.909 ± 0.009	1.276HisIle: 1.276 ± 0.009	1.3HisLys: 1.3 ± 0.008	2.929HisLeu: 2.929 ± 0.013	0.594HisMet: 0.594 ± 0.005	0.887HisAsn: 0.887 ± 0.007	1.641HisPro: 1.641 ± 0.011	1.369HisGln: 1.369 ± 0.011	1.584HisArg: 1.584 ± 0.011	2.328HisSer: 2.328 ± 0.016	1.563HisThr: 1.563 ± 0.014	1.5HisVal: 1.5 ± 0.01	0.355HisTrp: 0.355 ± 0.004	0.808HisTyr: 0.808 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.615IleAla: 2.615 ± 0.013	1.083IleCys: 1.083 ± 0.007	2.061IleAsp: 2.061 ± 0.012	2.685IleGlu: 2.685 ± 0.016	1.919IlePhe: 1.919 ± 0.013	2.248IleGly: 2.248 ± 0.013	1.401IleHis: 1.401 ± 0.011	2.445IleIle: 2.445 ± 0.015	2.73IleLys: 2.73 ± 0.018	4.62IleLeu: 4.62 ± 0.02	1.011IleMet: 1.011 ± 0.007	1.879IleAsn: 1.879 ± 0.012	2.652IlePro: 2.652 ± 0.013	2.345IleGln: 2.345 ± 0.014	2.406IleArg: 2.406 ± 0.014	3.771IleSer: 3.771 ± 0.017	2.634IleThr: 2.634 ± 0.021	2.554IleVal: 2.554 ± 0.018	0.522IleTrp: 0.522 ± 0.005	1.397IleTyr: 1.397 ± 0.009	0.0IleXaa: 0.0 ± 0.0
Lys	4.063LysAla: 4.063 ± 0.022	1.203LysCys: 1.203 ± 0.012	3.243LysAsp: 3.243 ± 0.02	5.266LysGlu: 5.266 ± 0.03	1.774LysPhe: 1.774 ± 0.011	3.328LysGly: 3.328 ± 0.021	1.438LysHis: 1.438 ± 0.011	2.905LysIle: 2.905 ± 0.017	4.851LysLys: 4.851 ± 0.029	5.269LysLeu: 5.269 ± 0.02	1.473LysMet: 1.473 ± 0.009	2.481LysAsn: 2.481 ± 0.012	3.181LysPro: 3.181 ± 0.023	2.689LysGln: 2.689 ± 0.013	3.333LysArg: 3.333 ± 0.016	3.947LysSer: 3.947 ± 0.017	3.185LysThr: 3.185 ± 0.016	3.58LysVal: 3.58 ± 0.023	0.627LysTrp: 0.627 ± 0.007	1.629LysTyr: 1.629 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.653LeuAla: 6.653 ± 0.028	2.174LeuCys: 2.174 ± 0.015	4.734LeuAsp: 4.734 ± 0.019	7.259LeuGlu: 7.259 ± 0.033	3.373LeuPhe: 3.373 ± 0.018	5.778LeuGly: 5.778 ± 0.024	2.729LeuHis: 2.729 ± 0.015	3.913LeuIle: 3.913 ± 0.017	5.937LeuLys: 5.937 ± 0.024	10.599LeuLeu: 10.599 ± 0.046	2.019LeuMet: 2.019 ± 0.011	3.543LeuAsn: 3.543 ± 0.015	5.918LeuPro: 5.918 ± 0.024	5.805LeuGln: 5.805 ± 0.028	5.811LeuArg: 5.811 ± 0.023	7.903LeuSer: 7.903 ± 0.028	5.097LeuThr: 5.097 ± 0.018	5.474LeuVal: 5.474 ± 0.021	1.128LeuTrp: 1.128 ± 0.009	2.533LeuTyr: 2.533 ± 0.014	0.001LeuXaa: 0.001 ± 0.0
Met	1.892MetAla: 1.892 ± 0.011	0.407MetCys: 0.407 ± 0.005	1.279MetAsp: 1.279 ± 0.009	1.912MetGlu: 1.912 ± 0.012	0.735MetPhe: 0.735 ± 0.007	1.296MetGly: 1.296 ± 0.011	0.479MetHis: 0.479 ± 0.005	0.858MetIle: 0.858 ± 0.007	1.48MetLys: 1.48 ± 0.009	1.987MetLeu: 1.987 ± 0.012	0.578MetMet: 0.578 ± 0.007	0.92MetAsn: 0.92 ± 0.007	1.1MetPro: 1.1 ± 0.009	0.943MetGln: 0.943 ± 0.008	1.048MetArg: 1.048 ± 0.007	1.559MetSer: 1.559 ± 0.01	1.149MetThr: 1.149 ± 0.007	1.4MetVal: 1.4 ± 0.009	0.245MetTrp: 0.245 ± 0.004	0.555MetTyr: 0.555 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.09AsnAla: 2.09 ± 0.012	0.846AsnCys: 0.846 ± 0.008	1.559AsnAsp: 1.559 ± 0.01	2.3AsnGlu: 2.3 ± 0.014	1.493AsnPhe: 1.493 ± 0.01	2.488AsnGly: 2.488 ± 0.014	0.965AsnHis: 0.965 ± 0.008	2.177AsnIle: 2.177 ± 0.014	2.269AsnLys: 2.269 ± 0.013	3.787AsnLeu: 3.787 ± 0.017	0.927AsnMet: 0.927 ± 0.008	1.563AsnAsn: 1.563 ± 0.01	2.19AsnPro: 2.19 ± 0.013	1.684AsnGln: 1.684 ± 0.012	1.872AsnArg: 1.872 ± 0.011	3.179AsnSer: 3.179 ± 0.014	1.984AsnThr: 1.984 ± 0.011	2.239AsnVal: 2.239 ± 0.013	0.466AsnTrp: 0.466 ± 0.005	1.153AsnTyr: 1.153 ± 0.009	0.001AsnXaa: 0.001 ± 0.0
Pro	4.618ProAla: 4.618 ± 0.026	1.126ProCys: 1.126 ± 0.012	2.782ProAsp: 2.782 ± 0.014	4.432ProGlu: 4.432 ± 0.02	1.904ProPhe: 1.904 ± 0.011	5.105ProGly: 5.105 ± 0.052	1.442ProHis: 1.442 ± 0.011	1.941ProIle: 1.941 ± 0.014	2.809ProLys: 2.809 ± 0.021	5.169ProLeu: 5.169 ± 0.023	1.034ProMet: 1.034 ± 0.008	1.829ProAsn: 1.829 ± 0.01	5.818ProPro: 5.818 ± 0.052	2.803ProGln: 2.803 ± 0.018	3.217ProArg: 3.217 ± 0.017	5.647ProSer: 5.647 ± 0.033	3.114ProThr: 3.114 ± 0.023	3.812ProVal: 3.812 ± 0.021	0.694ProTrp: 0.694 ± 0.005	1.548ProTyr: 1.548 ± 0.012	0.002ProXaa: 0.002 ± 0.0
Gln	3.513GlnAla: 3.513 ± 0.02	0.956GlnCys: 0.956 ± 0.011	2.338GlnAsp: 2.338 ± 0.012	3.97GlnGlu: 3.97 ± 0.023	1.4GlnPhe: 1.4 ± 0.008	2.858GlnGly: 2.858 ± 0.017	1.309GlnHis: 1.309 ± 0.009	2.031GlnIle: 2.031 ± 0.012	3.032GlnLys: 3.032 ± 0.015	4.723GlnLeu: 4.723 ± 0.024	1.129GlnMet: 1.129 ± 0.009	1.899GlnAsn: 1.899 ± 0.01	2.777GlnPro: 2.777 ± 0.019	3.124GlnGln: 3.124 ± 0.028	2.96GlnArg: 2.96 ± 0.018	3.16GlnSer: 3.16 ± 0.019	2.32GlnThr: 2.32 ± 0.013	2.849GlnVal: 2.849 ± 0.013	0.558GlnTrp: 0.558 ± 0.005	1.168GlnTyr: 1.168 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	3.663ArgAla: 3.663 ± 0.018	1.201ArgCys: 1.201 ± 0.011	2.75ArgAsp: 2.75 ± 0.012	3.964ArgGlu: 3.964 ± 0.02	1.832ArgPhe: 1.832 ± 0.011	3.526ArgGly: 3.526 ± 0.021	1.537ArgHis: 1.537 ± 0.01	2.487ArgIle: 2.487 ± 0.013	3.697ArgLys: 3.697 ± 0.017	5.343ArgLeu: 5.343 ± 0.021	1.214ArgMet: 1.214 ± 0.008	2.151ArgAsn: 2.151 ± 0.011	3.117ArgPro: 3.117 ± 0.017	2.616ArgGln: 2.616 ± 0.014	4.177ArgArg: 4.177 ± 0.026	4.201ArgSer: 4.201 ± 0.025	2.804ArgThr: 2.804 ± 0.015	3.158ArgVal: 3.158 ± 0.018	0.697ArgTrp: 0.697 ± 0.006	1.447ArgTyr: 1.447 ± 0.008	0.001ArgXaa: 0.001 ± 0.0
Ser	5.234SerAla: 5.234 ± 0.021	1.854SerCys: 1.854 ± 0.014	3.928SerAsp: 3.928 ± 0.019	5.225SerGlu: 5.225 ± 0.022	3.043SerPhe: 3.043 ± 0.016	5.569SerGly: 5.569 ± 0.022	2.138SerHis: 2.138 ± 0.013	3.266SerIle: 3.266 ± 0.015	4.144SerLys: 4.144 ± 0.018	8.174SerLeu: 8.174 ± 0.027	1.62SerMet: 1.62 ± 0.009	2.741SerAsn: 2.741 ± 0.016	5.947SerPro: 5.947 ± 0.034	3.9SerGln: 3.9 ± 0.019	4.507SerArg: 4.507 ± 0.024	9.31SerSer: 9.31 ± 0.048	4.47SerThr: 4.47 ± 0.025	4.868SerVal: 4.868 ± 0.019	1.079SerTrp: 1.079 ± 0.01	2.064SerTyr: 2.064 ± 0.011	0.001SerXaa: 0.001 ± 0.0
Thr	3.729ThrAla: 3.729 ± 0.017	1.293ThrCys: 1.293 ± 0.01	2.498ThrAsp: 2.498 ± 0.011	3.574ThrGlu: 3.574 ± 0.014	2.112ThrPhe: 2.112 ± 0.012	3.634ThrGly: 3.634 ± 0.019	1.338ThrHis: 1.338 ± 0.011	2.433ThrIle: 2.433 ± 0.015	2.727ThrLys: 2.727 ± 0.019	5.313ThrLeu: 5.313 ± 0.018	1.121ThrMet: 1.121 ± 0.008	1.798ThrAsn: 1.798 ± 0.011	3.584ThrPro: 3.584 ± 0.024	2.32ThrGln: 2.32 ± 0.013	2.463ThrArg: 2.463 ± 0.012	4.663ThrSer: 4.663 ± 0.025	3.077ThrThr: 3.077 ± 0.028	3.881ThrVal: 3.881 ± 0.021	0.707ThrTrp: 0.707 ± 0.007	1.429ThrTyr: 1.429 ± 0.009	0.0ThrXaa: 0.0 ± 0.0
Val	4.236ValAla: 4.236 ± 0.018	1.429ValCys: 1.429 ± 0.01	2.985ValAsp: 2.985 ± 0.015	3.927ValGlu: 3.927 ± 0.02	2.409ValPhe: 2.409 ± 0.014	3.376ValGly: 3.376 ± 0.016	1.567ValHis: 1.567 ± 0.009	2.951ValIle: 2.951 ± 0.016	3.493ValLys: 3.493 ± 0.022	6.122ValLeu: 6.122 ± 0.021	1.319ValMet: 1.319 ± 0.008	2.309ValAsn: 2.309 ± 0.012	3.618ValPro: 3.618 ± 0.021	2.753ValGln: 2.753 ± 0.012	3.021ValArg: 3.021 ± 0.014	4.885ValSer: 4.885 ± 0.02	3.83ValThr: 3.83 ± 0.027	3.984ValVal: 3.984 ± 0.018	0.725ValTrp: 0.725 ± 0.006	1.624ValTyr: 1.624 ± 0.01	0.0ValXaa: 0.0 ± 0.0
Trp	0.784TrpAla: 0.784 ± 0.006	0.248TrpCys: 0.248 ± 0.003	0.653TrpAsp: 0.653 ± 0.007	0.831TrpGlu: 0.831 ± 0.007	0.447TrpPhe: 0.447 ± 0.005	0.731TrpGly: 0.731 ± 0.008	0.317TrpHis: 0.317 ± 0.004	0.552TrpIle: 0.552 ± 0.005	0.829TrpLys: 0.829 ± 0.007	1.22TrpLeu: 1.22 ± 0.009	0.326TrpMet: 0.326 ± 0.004	0.545TrpAsn: 0.545 ± 0.007	0.533TrpPro: 0.533 ± 0.005	0.546TrpGln: 0.546 ± 0.005	0.717TrpArg: 0.717 ± 0.006	0.89TrpSer: 0.89 ± 0.008	0.678TrpThr: 0.678 ± 0.007	0.696TrpVal: 0.696 ± 0.005	0.196TrpTrp: 0.196 ± 0.003	0.343TrpTyr: 0.343 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.386TyrAla: 1.386 ± 0.009	0.678TyrCys: 0.678 ± 0.007	1.303TyrAsp: 1.303 ± 0.01	1.753TyrGlu: 1.753 ± 0.012	1.216TyrPhe: 1.216 ± 0.01	1.661TyrGly: 1.661 ± 0.013	0.759TyrHis: 0.759 ± 0.006	1.408TyrIle: 1.408 ± 0.011	1.565TyrLys: 1.565 ± 0.022	2.63TyrLeu: 2.63 ± 0.014	0.599TyrMet: 0.599 ± 0.006	1.124TyrAsn: 1.124 ± 0.009	1.297TyrPro: 1.297 ± 0.01	1.294TyrGln: 1.294 ± 0.009	1.622TyrArg: 1.622 ± 0.01	2.189TyrSer: 2.189 ± 0.013	1.467TyrThr: 1.467 ± 0.011	1.578TyrVal: 1.578 ± 0.009	0.368TyrTrp: 0.368 ± 0.005	0.943TyrTyr: 0.943 ± 0.008	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.286XaaXaa: 0.286 ± 0.036

Statistics based on 40241 proteins (21242615 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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