Amino acid dipepetide frequency for Levilactobacillus bambusae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.663AlaAla: 7.663 ± 0.136
0.327AlaCys: 0.327 ± 0.026
5.484AlaAsp: 5.484 ± 0.109
4.711AlaGlu: 4.711 ± 0.105
3.12AlaPhe: 3.12 ± 0.079
6.134AlaGly: 6.134 ± 0.11
1.68AlaHis: 1.68 ± 0.056
5.715AlaIle: 5.715 ± 0.119
4.985AlaLys: 4.985 ± 0.119
7.798AlaLeu: 7.798 ± 0.148
2.234AlaMet: 2.234 ± 0.072
3.852AlaAsn: 3.852 ± 0.083
2.575AlaPro: 2.575 ± 0.075
3.63AlaGln: 3.63 ± 0.092
3.019AlaArg: 3.019 ± 0.089
4.512AlaSer: 4.512 ± 0.108
5.223AlaThr: 5.223 ± 0.101
6.08AlaVal: 6.08 ± 0.108
0.836AlaTrp: 0.836 ± 0.039
2.843AlaTyr: 2.843 ± 0.065
0.0AlaXaa: 0.0 ± 0.0
Cys
0.307CysAla: 0.307 ± 0.021
0.044CysCys: 0.044 ± 0.008
0.222CysAsp: 0.222 ± 0.021
0.197CysGlu: 0.197 ± 0.022
0.192CysPhe: 0.192 ± 0.018
0.423CysGly: 0.423 ± 0.029
0.139CysHis: 0.139 ± 0.016
0.254CysIle: 0.254 ± 0.022
0.089CysLys: 0.089 ± 0.014
0.515CysLeu: 0.515 ± 0.031
0.083CysMet: 0.083 ± 0.014
0.135CysAsn: 0.135 ± 0.014
0.201CysPro: 0.201 ± 0.025
0.234CysGln: 0.234 ± 0.021
0.158CysArg: 0.158 ± 0.019
0.222CysSer: 0.222 ± 0.019
0.199CysThr: 0.199 ± 0.02
0.298CysVal: 0.298 ± 0.025
0.069CysTrp: 0.069 ± 0.01
0.181CysTyr: 0.181 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
4.654AspAla: 4.654 ± 0.121
0.218AspCys: 0.218 ± 0.017
3.862AspAsp: 3.862 ± 0.109
4.123AspGlu: 4.123 ± 0.093
2.596AspPhe: 2.596 ± 0.073
4.09AspGly: 4.09 ± 0.094
1.77AspHis: 1.77 ± 0.062
3.292AspIle: 3.292 ± 0.086
2.85AspLys: 2.85 ± 0.075
6.198AspLeu: 6.198 ± 0.13
1.648AspMet: 1.648 ± 0.055
2.468AspAsn: 2.468 ± 0.08
2.598AspPro: 2.598 ± 0.075
3.923AspGln: 3.923 ± 0.103
3.031AspArg: 3.031 ± 0.084
3.184AspSer: 3.184 ± 0.154
2.982AspThr: 2.982 ± 0.113
4.562AspVal: 4.562 ± 0.147
0.881AspTrp: 0.881 ± 0.041
2.538AspTyr: 2.538 ± 0.062
0.0AspXaa: 0.0 ± 0.0
Glu
4.891GluAla: 4.891 ± 0.103
0.146GluCys: 0.146 ± 0.017
2.96GluAsp: 2.96 ± 0.082
3.046GluGlu: 3.046 ± 0.095
1.998GluPhe: 1.998 ± 0.069
2.902GluGly: 2.902 ± 0.073
1.186GluHis: 1.186 ± 0.05
3.63GluIle: 3.63 ± 0.093
3.232GluLys: 3.232 ± 0.078
5.599GluLeu: 5.599 ± 0.119
1.765GluMet: 1.765 ± 0.056
2.552GluAsn: 2.552 ± 0.076
1.964GluPro: 1.964 ± 0.067
2.625GluGln: 2.625 ± 0.079
2.79GluArg: 2.79 ± 0.08
2.971GluSer: 2.971 ± 0.08
3.919GluThr: 3.919 ± 0.155
3.823GluVal: 3.823 ± 0.151
0.577GluTrp: 0.577 ± 0.034
1.453GluTyr: 1.453 ± 0.054
0.0GluXaa: 0.0 ± 0.0
Phe
3.005PheAla: 3.005 ± 0.094
0.256PheCys: 0.256 ± 0.022
2.784PheAsp: 2.784 ± 0.08
2.033PheGlu: 2.033 ± 0.063
1.873PhePhe: 1.873 ± 0.066
3.216PheGly: 3.216 ± 0.078
0.829PheHis: 0.829 ± 0.043
2.729PheIle: 2.729 ± 0.091
2.012PheLys: 2.012 ± 0.061
3.683PheLeu: 3.683 ± 0.094
1.099PheMet: 1.099 ± 0.04
2.202PheAsn: 2.202 ± 0.068
1.49PhePro: 1.49 ± 0.057
1.486PheGln: 1.486 ± 0.053
1.399PheArg: 1.399 ± 0.049
2.928PheSer: 2.928 ± 0.078
2.42PheThr: 2.42 ± 0.068
2.79PheVal: 2.79 ± 0.074
0.6PheTrp: 0.6 ± 0.034
1.577PheTyr: 1.577 ± 0.054
0.0PheXaa: 0.0 ± 0.0
Gly
5.111GlyAla: 5.111 ± 0.112
0.35GlyCys: 0.35 ± 0.026
3.83GlyAsp: 3.83 ± 0.093
3.493GlyGlu: 3.493 ± 0.084
2.9GlyPhe: 2.9 ± 0.08
4.317GlyGly: 4.317 ± 0.109
1.763GlyHis: 1.763 ± 0.057
5.461GlyIle: 5.461 ± 0.112
3.877GlyLys: 3.877 ± 0.092
6.951GlyLeu: 6.951 ± 0.134
2.159GlyMet: 2.159 ± 0.059
2.795GlyAsn: 2.795 ± 0.088
1.724GlyPro: 1.724 ± 0.057
3.339GlyGln: 3.339 ± 0.076
3.053GlyArg: 3.053 ± 0.089
4.115GlySer: 4.115 ± 0.092
4.503GlyThr: 4.503 ± 0.098
5.098GlyVal: 5.098 ± 0.105
0.845GlyTrp: 0.845 ± 0.044
2.706GlyTyr: 2.706 ± 0.069
0.0GlyXaa: 0.0 ± 0.0
His
1.579HisAla: 1.579 ± 0.055
0.101HisCys: 0.101 ± 0.014
1.52HisAsp: 1.52 ± 0.054
1.236HisGlu: 1.236 ± 0.047
1.028HisPhe: 1.028 ± 0.044
1.648HisGly: 1.648 ± 0.061
0.844HisHis: 0.844 ± 0.04
1.137HisIle: 1.137 ± 0.04
0.918HisLys: 0.918 ± 0.034
2.33HisLeu: 2.33 ± 0.065
0.638HisMet: 0.638 ± 0.032
0.833HisAsn: 0.833 ± 0.037
1.273HisPro: 1.273 ± 0.048
1.426HisGln: 1.426 ± 0.05
1.268HisArg: 1.268 ± 0.053
1.044HisSer: 1.044 ± 0.045
1.113HisThr: 1.113 ± 0.046
1.717HisVal: 1.717 ± 0.067
0.316HisTrp: 0.316 ± 0.024
1.057HisTyr: 1.057 ± 0.05
0.0HisXaa: 0.0 ± 0.0
Ile
5.324IleAla: 5.324 ± 0.109
0.396IleCys: 0.396 ± 0.026
3.939IleAsp: 3.939 ± 0.092
3.381IleGlu: 3.381 ± 0.081
2.628IlePhe: 2.628 ± 0.083
5.026IleGly: 5.026 ± 0.112
1.438IleHis: 1.438 ± 0.057
4.388IleIle: 4.388 ± 0.103
3.166IleLys: 3.166 ± 0.095
6.175IleLeu: 6.175 ± 0.13
1.648IleMet: 1.648 ± 0.051
3.104IleAsn: 3.104 ± 0.07
2.754IlePro: 2.754 ± 0.072
2.852IleGln: 2.852 ± 0.074
2.653IleArg: 2.653 ± 0.069
4.26IleSer: 4.26 ± 0.091
4.257IleThr: 4.257 ± 0.092
4.743IleVal: 4.743 ± 0.099
0.641IleTrp: 0.641 ± 0.041
1.968IleTyr: 1.968 ± 0.062
0.0IleXaa: 0.0 ± 0.0
Lys
4.2LysAla: 4.2 ± 0.102
0.107LysCys: 0.107 ± 0.015
2.927LysAsp: 2.927 ± 0.082
2.765LysGlu: 2.765 ± 0.076
1.593LysPhe: 1.593 ± 0.046
2.911LysGly: 2.911 ± 0.078
1.019LysHis: 1.019 ± 0.045
3.17LysIle: 3.17 ± 0.084
3.651LysLys: 3.651 ± 0.093
4.601LysLeu: 4.601 ± 0.094
1.897LysMet: 1.897 ± 0.056
2.662LysAsn: 2.662 ± 0.074
2.016LysPro: 2.016 ± 0.06
2.989LysGln: 2.989 ± 0.074
3.069LysArg: 3.069 ± 0.082
3.138LysSer: 3.138 ± 0.086
4.09LysThr: 4.09 ± 0.103
3.474LysVal: 3.474 ± 0.083
0.575LysTrp: 0.575 ± 0.037
1.538LysTyr: 1.538 ± 0.056
0.0LysXaa: 0.0 ± 0.0
Leu
9.101LeuAla: 9.101 ± 0.141
0.417LeuCys: 0.417 ± 0.026
5.857LeuAsp: 5.857 ± 0.13
4.456LeuGlu: 4.456 ± 0.093
4.033LeuPhe: 4.033 ± 0.109
6.867LeuGly: 6.867 ± 0.131
1.877LeuHis: 1.877 ± 0.07
6.814LeuIle: 6.814 ± 0.149
5.223LeuLys: 5.223 ± 0.096
9.138LeuLeu: 9.138 ± 0.194
2.87LeuMet: 2.87 ± 0.072
4.738LeuAsn: 4.738 ± 0.084
4.072LeuPro: 4.072 ± 0.076
3.6LeuGln: 3.6 ± 0.091
3.786LeuArg: 3.786 ± 0.09
7.119LeuSer: 7.119 ± 0.3
7.776LeuThr: 7.776 ± 0.141
7.213LeuVal: 7.213 ± 0.125
0.978LeuTrp: 0.978 ± 0.038
2.79LeuTyr: 2.79 ± 0.075
0.0LeuXaa: 0.0 ± 0.0
Met
2.774MetAla: 2.774 ± 0.064
0.114MetCys: 0.114 ± 0.014
1.611MetAsp: 1.611 ± 0.048
1.177MetGlu: 1.177 ± 0.057
0.9MetPhe: 0.9 ± 0.039
2.04MetGly: 2.04 ± 0.055
0.451MetHis: 0.451 ± 0.029
1.794MetIle: 1.794 ± 0.059
1.866MetLys: 1.866 ± 0.059
2.282MetLeu: 2.282 ± 0.061
0.92MetMet: 0.92 ± 0.038
1.399MetAsn: 1.399 ± 0.049
1.14MetPro: 1.14 ± 0.036
1.17MetGln: 1.17 ± 0.042
1.039MetArg: 1.039 ± 0.04
1.854MetSer: 1.854 ± 0.056
2.412MetThr: 2.412 ± 0.068
2.037MetVal: 2.037 ± 0.067
0.243MetTrp: 0.243 ± 0.02
0.618MetTyr: 0.618 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
3.463AsnAla: 3.463 ± 0.091
0.178AsnCys: 0.178 ± 0.018
2.806AsnAsp: 2.806 ± 0.082
2.536AsnGlu: 2.536 ± 0.062
1.755AsnPhe: 1.755 ± 0.065
3.603AsnGly: 3.603 ± 0.088
1.273AsnHis: 1.273 ± 0.046
2.328AsnIle: 2.328 ± 0.057
1.955AsnLys: 1.955 ± 0.067
4.232AsnLeu: 4.232 ± 0.093
1.247AsnMet: 1.247 ± 0.046
1.882AsnAsn: 1.882 ± 0.079
2.316AsnPro: 2.316 ± 0.073
3.113AsnGln: 3.113 ± 0.087
2.525AsnArg: 2.525 ± 0.06
2.394AsnSer: 2.394 ± 0.087
2.349AsnThr: 2.349 ± 0.068
3.269AsnVal: 3.269 ± 0.077
0.606AsnTrp: 0.606 ± 0.033
1.63AsnTyr: 1.63 ± 0.066
0.0AsnXaa: 0.0 ± 0.0
Pro
3.196ProAla: 3.196 ± 0.083
0.082ProCys: 0.082 ± 0.013
2.868ProAsp: 2.868 ± 0.075
2.96ProGlu: 2.96 ± 0.068
1.666ProPhe: 1.666 ± 0.054
2.404ProGly: 2.404 ± 0.072
0.803ProHis: 0.803 ± 0.036
2.461ProIle: 2.461 ± 0.064
2.127ProLys: 2.127 ± 0.063
3.6ProLeu: 3.6 ± 0.087
0.916ProMet: 0.916 ± 0.044
1.966ProAsn: 1.966 ± 0.053
0.611ProPro: 0.611 ± 0.03
1.543ProGln: 1.543 ± 0.049
1.332ProArg: 1.332 ± 0.053
2.005ProSer: 2.005 ± 0.058
2.733ProThr: 2.733 ± 0.079
3.353ProVal: 3.353 ± 0.085
0.368ProTrp: 0.368 ± 0.028
1.406ProTyr: 1.406 ± 0.054
0.0ProXaa: 0.0 ± 0.0
Gln
4.045GlnAla: 4.045 ± 0.095
0.114GlnCys: 0.114 ± 0.015
2.401GlnAsp: 2.401 ± 0.065
2.328GlnGlu: 2.328 ± 0.071
2.136GlnPhe: 2.136 ± 0.066
2.357GlnGly: 2.357 ± 0.067
1.026GlnHis: 1.026 ± 0.042
3.196GlnIle: 3.196 ± 0.074
2.582GlnLys: 2.582 ± 0.063
5.878GlnLeu: 5.878 ± 0.141
1.383GlnMet: 1.383 ± 0.048
2.103GlnAsn: 2.103 ± 0.08
2.103GlnPro: 2.103 ± 0.067
2.625GlnGln: 2.625 ± 0.095
2.493GlnArg: 2.493 ± 0.087
2.863GlnSer: 2.863 ± 0.08
3.461GlnThr: 3.461 ± 0.081
3.472GlnVal: 3.472 ± 0.084
0.478GlnTrp: 0.478 ± 0.029
1.561GlnTyr: 1.561 ± 0.055
0.0GlnXaa: 0.0 ± 0.0
Arg
3.198ArgAla: 3.198 ± 0.08
0.181ArgCys: 0.181 ± 0.016
2.582ArgAsp: 2.582 ± 0.073
2.642ArgGlu: 2.642 ± 0.075
2.017ArgPhe: 2.017 ± 0.056
2.676ArgGly: 2.676 ± 0.069
1.2ArgHis: 1.2 ± 0.048
2.854ArgIle: 2.854 ± 0.07
2.042ArgLys: 2.042 ± 0.069
4.956ArgLeu: 4.956 ± 0.107
1.229ArgMet: 1.229 ± 0.051
1.794ArgAsn: 1.794 ± 0.061
1.657ArgPro: 1.657 ± 0.06
2.641ArgGln: 2.641 ± 0.079
2.39ArgArg: 2.39 ± 0.08
2.36ArgSer: 2.36 ± 0.063
2.376ArgThr: 2.376 ± 0.068
3.204ArgVal: 3.204 ± 0.09
0.483ArgTrp: 0.483 ± 0.031
1.838ArgTyr: 1.838 ± 0.061
0.0ArgXaa: 0.0 ± 0.0
Ser
4.919SerAla: 4.919 ± 0.126
0.215SerCys: 0.215 ± 0.021
4.031SerAsp: 4.031 ± 0.106
3.591SerGlu: 3.591 ± 0.15
2.435SerPhe: 2.435 ± 0.058
4.633SerGly: 4.633 ± 0.099
1.453SerHis: 1.453 ± 0.055
3.374SerIle: 3.374 ± 0.084
2.848SerLys: 2.848 ± 0.088
6.123SerLeu: 6.123 ± 0.234
1.479SerMet: 1.479 ± 0.058
2.541SerAsn: 2.541 ± 0.075
2.044SerPro: 2.044 ± 0.055
3.015SerGln: 3.015 ± 0.087
2.618SerArg: 2.618 ± 0.079
4.262SerSer: 4.262 ± 0.2
3.779SerThr: 3.779 ± 0.122
4.241SerVal: 4.241 ± 0.104
0.721SerTrp: 0.721 ± 0.035
2.053SerTyr: 2.053 ± 0.069
0.0SerXaa: 0.0 ± 0.0
Thr
5.411ThrAla: 5.411 ± 0.098
0.236ThrCys: 0.236 ± 0.024
4.219ThrAsp: 4.219 ± 0.131
3.495ThrGlu: 3.495 ± 0.134
2.594ThrPhe: 2.594 ± 0.077
4.992ThrGly: 4.992 ± 0.106
1.506ThrHis: 1.506 ± 0.049
4.472ThrIle: 4.472 ± 0.085
3.317ThrLys: 3.317 ± 0.094
6.523ThrLeu: 6.523 ± 0.116
1.554ThrMet: 1.554 ± 0.058
2.9ThrAsn: 2.9 ± 0.079
3.042ThrPro: 3.042 ± 0.072
2.729ThrGln: 2.729 ± 0.074
2.458ThrArg: 2.458 ± 0.064
3.958ThrSer: 3.958 ± 0.109
4.621ThrThr: 4.621 ± 0.097
5.43ThrVal: 5.43 ± 0.126
0.742ThrTrp: 0.742 ± 0.034
2.381ThrTyr: 2.381 ± 0.074
0.0ThrXaa: 0.0 ± 0.0
Val
6.354ValAla: 6.354 ± 0.126
0.428ValCys: 0.428 ± 0.03
4.798ValAsp: 4.798 ± 0.172
3.664ValGlu: 3.664 ± 0.094
2.68ValPhe: 2.68 ± 0.074
5.093ValGly: 5.093 ± 0.106
1.43ValHis: 1.43 ± 0.046
5.191ValIle: 5.191 ± 0.113
4.065ValLys: 4.065 ± 0.096
6.773ValLeu: 6.773 ± 0.151
1.968ValMet: 1.968 ± 0.056
3.521ValAsn: 3.521 ± 0.078
2.994ValPro: 2.994 ± 0.081
2.749ValGln: 2.749 ± 0.083
2.8ValArg: 2.8 ± 0.079
4.679ValSer: 4.679 ± 0.105
5.736ValThr: 5.736 ± 0.137
5.32ValVal: 5.32 ± 0.11
0.769ValTrp: 0.769 ± 0.042
2.23ValTyr: 2.23 ± 0.071
0.0ValXaa: 0.0 ± 0.0
Trp
0.744TrpAla: 0.744 ± 0.039
0.057TrpCys: 0.057 ± 0.011
0.588TrpAsp: 0.588 ± 0.037
0.44TrpGlu: 0.44 ± 0.03
0.577TrpPhe: 0.577 ± 0.034
0.7TrpGly: 0.7 ± 0.038
0.362TrpHis: 0.362 ± 0.025
0.753TrpIle: 0.753 ± 0.041
0.408TrpLys: 0.408 ± 0.029
1.58TrpLeu: 1.58 ± 0.06
0.33TrpMet: 0.33 ± 0.026
0.526TrpAsn: 0.526 ± 0.032
0.384TrpPro: 0.384 ± 0.024
0.646TrpGln: 0.646 ± 0.032
0.604TrpArg: 0.604 ± 0.033
0.613TrpSer: 0.613 ± 0.036
0.606TrpThr: 0.606 ± 0.037
0.78TrpVal: 0.78 ± 0.04
0.211TrpTrp: 0.211 ± 0.022
0.426TrpTyr: 0.426 ± 0.032
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.481TyrAla: 2.481 ± 0.069
0.197TyrCys: 0.197 ± 0.021
2.181TyrAsp: 2.181 ± 0.063
1.753TyrGlu: 1.753 ± 0.055
1.692TyrPhe: 1.692 ± 0.06
2.36TyrGly: 2.36 ± 0.067
0.975TyrHis: 0.975 ± 0.042
1.73TyrIle: 1.73 ± 0.054
1.176TyrLys: 1.176 ± 0.042
3.791TyrLeu: 3.791 ± 0.086
0.772TyrMet: 0.772 ± 0.035
1.486TyrAsn: 1.486 ± 0.06
1.444TyrPro: 1.444 ± 0.048
2.269TyrGln: 2.269 ± 0.069
1.836TyrArg: 1.836 ± 0.058
1.893TyrSer: 1.893 ± 0.061
2.026TyrThr: 2.026 ± 0.07
2.337TyrVal: 2.337 ± 0.059
0.394TyrTrp: 0.394 ± 0.028
1.284TyrTyr: 1.284 ± 0.049
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1886 proteins (563121 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski