Amino acid dipepetide frequency for Sellimonas intestinalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.555AlaAla: 6.555 ± 0.117	1.128AlaCys: 1.128 ± 0.04	4.004AlaAsp: 4.004 ± 0.066	4.83AlaGlu: 4.83 ± 0.08	3.009AlaPhe: 3.009 ± 0.061	5.986AlaGly: 5.986 ± 0.098	1.096AlaHis: 1.096 ± 0.039	4.622AlaIle: 4.622 ± 0.079	4.865AlaLys: 4.865 ± 0.076	6.818AlaLeu: 6.818 ± 0.089	2.308AlaMet: 2.308 ± 0.05	2.289AlaAsn: 2.289 ± 0.053	1.942AlaPro: 1.942 ± 0.055	2.024AlaGln: 2.024 ± 0.054	3.137AlaArg: 3.137 ± 0.057	3.805AlaSer: 3.805 ± 0.076	2.807AlaThr: 2.807 ± 0.064	6.231AlaVal: 6.231 ± 0.08	0.659AlaTrp: 0.659 ± 0.03	2.714AlaTyr: 2.714 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.001CysAla: 1.001 ± 0.033	0.276CysCys: 0.276 ± 0.019	0.775CysAsp: 0.775 ± 0.03	0.997CysGlu: 0.997 ± 0.037	0.675CysPhe: 0.675 ± 0.026	1.532CysGly: 1.532 ± 0.045	0.386CysHis: 0.386 ± 0.019	1.079CysIle: 1.079 ± 0.032	0.809CysLys: 0.809 ± 0.027	1.229CysLeu: 1.229 ± 0.043	0.472CysMet: 0.472 ± 0.023	0.5CysAsn: 0.5 ± 0.023	0.669CysPro: 0.669 ± 0.031	0.454CysGln: 0.454 ± 0.022	0.796CysArg: 0.796 ± 0.03	0.787CysSer: 0.787 ± 0.028	0.77CysThr: 0.77 ± 0.028	1.045CysVal: 1.045 ± 0.035	0.125CysTrp: 0.125 ± 0.011	0.58CysTyr: 0.58 ± 0.028	0.0CysXaa: 0.0 ± 0.0
Asp	3.696AspAla: 3.696 ± 0.07	0.795AspCys: 0.795 ± 0.029	2.614AspAsp: 2.614 ± 0.062	4.45AspGlu: 4.45 ± 0.082	2.51AspPhe: 2.51 ± 0.052	4.425AspGly: 4.425 ± 0.094	0.982AspHis: 0.982 ± 0.034	4.155AspIle: 4.155 ± 0.088	2.967AspLys: 2.967 ± 0.061	4.889AspLeu: 4.889 ± 0.076	1.704AspMet: 1.704 ± 0.045	1.766AspAsn: 1.766 ± 0.047	1.938AspPro: 1.938 ± 0.05	1.577AspGln: 1.577 ± 0.04	2.704AspArg: 2.704 ± 0.059	2.678AspSer: 2.678 ± 0.07	2.895AspThr: 2.895 ± 0.055	3.793AspVal: 3.793 ± 0.063	0.578AspTrp: 0.578 ± 0.027	2.611AspTyr: 2.611 ± 0.064	0.0AspXaa: 0.0 ± 0.0
Glu	5.716GluAla: 5.716 ± 0.084	0.799GluCys: 0.799 ± 0.03	4.253GluAsp: 4.253 ± 0.073	8.539GluGlu: 8.539 ± 0.137	2.685GluPhe: 2.685 ± 0.055	4.819GluGly: 4.819 ± 0.079	1.536GluHis: 1.536 ± 0.036	6.263GluIle: 6.263 ± 0.091	7.192GluLys: 7.192 ± 0.098	6.603GluLeu: 6.603 ± 0.089	2.788GluMet: 2.788 ± 0.052	3.754GluAsn: 3.754 ± 0.062	1.971GluPro: 1.971 ± 0.051	3.089GluGln: 3.089 ± 0.064	4.051GluArg: 4.051 ± 0.077	3.467GluSer: 3.467 ± 0.069	4.312GluThr: 4.312 ± 0.076	4.683GluVal: 4.683 ± 0.078	0.774GluTrp: 0.774 ± 0.03	3.095GluTyr: 3.095 ± 0.065	0.0GluXaa: 0.0 ± 0.0
Phe	2.955PheAla: 2.955 ± 0.06	0.829PheCys: 0.829 ± 0.029	2.472PheAsp: 2.472 ± 0.059	2.828PheGlu: 2.828 ± 0.052	2.093PhePhe: 2.093 ± 0.058	3.262PheGly: 3.262 ± 0.06	1.01PheHis: 1.01 ± 0.037	2.689PheIle: 2.689 ± 0.055	1.618PheLys: 1.618 ± 0.041	4.499PheLeu: 4.499 ± 0.101	1.12PheMet: 1.12 ± 0.038	1.248PheAsn: 1.248 ± 0.038	1.495PhePro: 1.495 ± 0.039	1.635PheGln: 1.635 ± 0.041	2.01PheArg: 2.01 ± 0.051	2.898PheSer: 2.898 ± 0.056	2.284PheThr: 2.284 ± 0.047	2.813PheVal: 2.813 ± 0.057	0.486PheTrp: 0.486 ± 0.022	1.809PheTyr: 1.809 ± 0.051	0.0PheXaa: 0.0 ± 0.0
Gly	4.919GlyAla: 4.919 ± 0.081	1.326GlyCys: 1.326 ± 0.039	3.453GlyAsp: 3.453 ± 0.066	5.377GlyGlu: 5.377 ± 0.086	3.152GlyPhe: 3.152 ± 0.058	4.966GlyGly: 4.966 ± 0.086	1.253GlyHis: 1.253 ± 0.039	6.395GlyIle: 6.395 ± 0.087	5.719GlyLys: 5.719 ± 0.093	5.918GlyLeu: 5.918 ± 0.091	2.576GlyMet: 2.576 ± 0.054	2.954GlyAsn: 2.954 ± 0.048	1.455GlyPro: 1.455 ± 0.047	2.237GlyGln: 2.237 ± 0.046	3.461GlyArg: 3.461 ± 0.063	3.904GlySer: 3.904 ± 0.072	4.314GlyThr: 4.314 ± 0.077	5.013GlyVal: 5.013 ± 0.076	0.739GlyTrp: 0.739 ± 0.03	3.302GlyTyr: 3.302 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	1.196HisAla: 1.196 ± 0.038	0.312HisCys: 0.312 ± 0.018	0.92HisAsp: 0.92 ± 0.033	1.14HisGlu: 1.14 ± 0.037	0.863HisPhe: 0.863 ± 0.027	1.363HisGly: 1.363 ± 0.045	0.495HisHis: 0.495 ± 0.023	1.465HisIle: 1.465 ± 0.042	0.958HisLys: 0.958 ± 0.031	1.762HisLeu: 1.762 ± 0.049	0.551HisMet: 0.551 ± 0.021	0.677HisAsn: 0.677 ± 0.026	1.054HisPro: 1.054 ± 0.035	0.623HisGln: 0.623 ± 0.028	0.853HisArg: 0.853 ± 0.031	0.964HisSer: 0.964 ± 0.031	1.043HisThr: 1.043 ± 0.031	1.277HisVal: 1.277 ± 0.038	0.182HisTrp: 0.182 ± 0.015	0.876HisTyr: 0.876 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.336IleAla: 5.336 ± 0.073	1.345IleCys: 1.345 ± 0.041	3.901IleAsp: 3.901 ± 0.08	4.869IleGlu: 4.869 ± 0.085	3.009IlePhe: 3.009 ± 0.07	5.365IleGly: 5.365 ± 0.092	1.603IleHis: 1.603 ± 0.04	4.673IleIle: 4.673 ± 0.08	3.624IleLys: 3.624 ± 0.066	7.746IleLeu: 7.746 ± 0.116	1.911IleMet: 1.911 ± 0.044	2.416IleAsn: 2.416 ± 0.048	3.322IlePro: 3.322 ± 0.059	2.743IleGln: 2.743 ± 0.052	4.69IleArg: 4.69 ± 0.086	4.725IleSer: 4.725 ± 0.089	3.893IleThr: 3.893 ± 0.065	5.193IleVal: 5.193 ± 0.082	0.715IleTrp: 0.715 ± 0.03	2.715IleTyr: 2.715 ± 0.058	0.0IleXaa: 0.0 ± 0.0
Lys	4.796LysAla: 4.796 ± 0.08	0.668LysCys: 0.668 ± 0.029	3.704LysAsp: 3.704 ± 0.061	7.594LysGlu: 7.594 ± 0.103	1.806LysPhe: 1.806 ± 0.046	4.425LysGly: 4.425 ± 0.077	1.055LysHis: 1.055 ± 0.035	4.929LysIle: 4.929 ± 0.08	6.301LysLys: 6.301 ± 0.086	5.093LysLeu: 5.093 ± 0.073	2.213LysMet: 2.213 ± 0.046	3.113LysAsn: 3.113 ± 0.062	1.941LysPro: 1.941 ± 0.046	2.507LysGln: 2.507 ± 0.049	3.585LysArg: 3.585 ± 0.066	3.215LysSer: 3.215 ± 0.068	3.629LysThr: 3.629 ± 0.063	4.155LysVal: 4.155 ± 0.072	0.653LysTrp: 0.653 ± 0.027	2.677LysTyr: 2.677 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	6.636LeuAla: 6.636 ± 0.104	1.558LeuCys: 1.558 ± 0.043	4.933LeuAsp: 4.933 ± 0.074	6.394LeuGlu: 6.394 ± 0.083	4.151LeuPhe: 4.151 ± 0.088	6.062LeuGly: 6.062 ± 0.088	1.701LeuHis: 1.701 ± 0.049	6.305LeuIle: 6.305 ± 0.086	6.253LeuLys: 6.253 ± 0.085	8.905LeuLeu: 8.905 ± 0.133	2.612LeuMet: 2.612 ± 0.052	3.593LeuAsn: 3.593 ± 0.064	3.641LeuPro: 3.641 ± 0.07	2.792LeuGln: 2.792 ± 0.057	4.101LeuArg: 4.101 ± 0.082	6.233LeuSer: 6.233 ± 0.111	5.074LeuThr: 5.074 ± 0.079	5.523LeuVal: 5.523 ± 0.074	0.804LeuTrp: 0.804 ± 0.036	3.473LeuTyr: 3.473 ± 0.07	0.0LeuXaa: 0.0 ± 0.0
Met	2.295MetAla: 2.295 ± 0.056	0.307MetCys: 0.307 ± 0.018	1.852MetAsp: 1.852 ± 0.045	2.986MetGlu: 2.986 ± 0.055	1.008MetPhe: 1.008 ± 0.033	2.09MetGly: 2.09 ± 0.043	0.434MetHis: 0.434 ± 0.02	2.476MetIle: 2.476 ± 0.055	2.793MetLys: 2.793 ± 0.054	2.734MetLeu: 2.734 ± 0.049	1.092MetMet: 1.092 ± 0.036	1.431MetAsn: 1.431 ± 0.038	1.079MetPro: 1.079 ± 0.031	1.076MetGln: 1.076 ± 0.036	1.493MetArg: 1.493 ± 0.04	1.711MetSer: 1.711 ± 0.042	1.857MetThr: 1.857 ± 0.042	1.856MetVal: 1.856 ± 0.046	0.25MetTrp: 0.25 ± 0.016	0.93MetTyr: 0.93 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	2.487AsnAla: 2.487 ± 0.058	0.603AsnCys: 0.603 ± 0.023	1.806AsnAsp: 1.806 ± 0.044	2.747AsnGlu: 2.747 ± 0.058	1.422AsnPhe: 1.422 ± 0.043	3.177AsnGly: 3.177 ± 0.057	0.79AsnHis: 0.79 ± 0.033	2.913AsnIle: 2.913 ± 0.066	2.08AsnLys: 2.08 ± 0.054	3.583AsnLeu: 3.583 ± 0.055	1.284AsnMet: 1.284 ± 0.035	1.453AsnAsn: 1.453 ± 0.053	1.89AsnPro: 1.89 ± 0.048	1.502AsnGln: 1.502 ± 0.042	2.041AsnArg: 2.041 ± 0.047	2.006AsnSer: 2.006 ± 0.043	2.1AsnThr: 2.1 ± 0.054	2.507AsnVal: 2.507 ± 0.055	0.391AsnTrp: 0.391 ± 0.023	1.66AsnTyr: 1.66 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	2.341ProAla: 2.341 ± 0.057	0.504ProCys: 0.504 ± 0.026	2.427ProAsp: 2.427 ± 0.054	3.43ProGlu: 3.43 ± 0.072	1.712ProPhe: 1.712 ± 0.049	2.493ProGly: 2.493 ± 0.05	0.602ProHis: 0.602 ± 0.027	2.019ProIle: 2.019 ± 0.044	2.188ProLys: 2.188 ± 0.051	2.721ProLeu: 2.721 ± 0.055	0.917ProMet: 0.917 ± 0.034	1.224ProAsn: 1.224 ± 0.038	0.833ProPro: 0.833 ± 0.036	1.08ProGln: 1.08 ± 0.036	1.097ProArg: 1.097 ± 0.033	1.872ProSer: 1.872 ± 0.045	1.517ProThr: 1.517 ± 0.038	3.078ProVal: 3.078 ± 0.064	0.367ProTrp: 0.367 ± 0.022	1.564ProTyr: 1.564 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.358GlnAla: 2.358 ± 0.061	0.349GlnCys: 0.349 ± 0.019	1.648GlnAsp: 1.648 ± 0.043	3.076GlnGlu: 3.076 ± 0.056	1.286GlnPhe: 1.286 ± 0.033	2.111GlnGly: 2.111 ± 0.051	0.481GlnHis: 0.481 ± 0.021	2.963GlnIle: 2.963 ± 0.056	3.027GlnLys: 3.027 ± 0.058	2.41GlnLeu: 2.41 ± 0.059	1.339GlnMet: 1.339 ± 0.038	1.591GlnAsn: 1.591 ± 0.046	0.867GlnPro: 0.867 ± 0.031	1.031GlnGln: 1.031 ± 0.035	1.519GlnArg: 1.519 ± 0.04	1.685GlnSer: 1.685 ± 0.044	1.775GlnThr: 1.775 ± 0.051	2.111GlnVal: 2.111 ± 0.042	0.307GlnTrp: 0.307 ± 0.019	1.452GlnTyr: 1.452 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.928ArgAla: 2.928 ± 0.061	0.65ArgCys: 0.65 ± 0.03	2.4ArgAsp: 2.4 ± 0.062	4.561ArgGlu: 4.561 ± 0.078	2.077ArgPhe: 2.077 ± 0.05	2.787ArgGly: 2.787 ± 0.058	0.935ArgHis: 0.935 ± 0.032	4.163ArgIle: 4.163 ± 0.068	4.231ArgLys: 4.231 ± 0.07	4.339ArgLeu: 4.339 ± 0.076	1.865ArgMet: 1.865 ± 0.054	2.077ArgAsn: 2.077 ± 0.04	1.516ArgPro: 1.516 ± 0.044	1.966ArgGln: 1.966 ± 0.052	2.786ArgArg: 2.786 ± 0.061	2.276ArgSer: 2.276 ± 0.047	2.656ArgThr: 2.656 ± 0.059	2.796ArgVal: 2.796 ± 0.05	0.475ArgTrp: 0.475 ± 0.029	2.071ArgTyr: 2.071 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	3.82SerAla: 3.82 ± 0.074	0.82SerCys: 0.82 ± 0.029	3.046SerAsp: 3.046 ± 0.06	3.85SerGlu: 3.85 ± 0.083	2.689SerPhe: 2.689 ± 0.059	5.075SerGly: 5.075 ± 0.084	1.019SerHis: 1.019 ± 0.03	4.045SerIle: 4.045 ± 0.083	3.017SerLys: 3.017 ± 0.066	5.046SerLeu: 5.046 ± 0.08	1.83SerMet: 1.83 ± 0.044	1.831SerAsn: 1.831 ± 0.042	1.77SerPro: 1.77 ± 0.043	1.745SerGln: 1.745 ± 0.049	2.834SerArg: 2.834 ± 0.054	3.327SerSer: 3.327 ± 0.076	2.6SerThr: 2.6 ± 0.062	4.119SerVal: 4.119 ± 0.078	0.549SerTrp: 0.549 ± 0.024	2.372SerTyr: 2.372 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	4.189ThrAla: 4.189 ± 0.066	0.663ThrCys: 0.663 ± 0.029	3.063ThrAsp: 3.063 ± 0.049	3.869ThrGlu: 3.869 ± 0.067	2.245ThrPhe: 2.245 ± 0.054	4.668ThrGly: 4.668 ± 0.109	0.942ThrHis: 0.942 ± 0.034	3.896ThrIle: 3.896 ± 0.061	3.226ThrLys: 3.226 ± 0.056	4.742ThrLeu: 4.742 ± 0.084	1.556ThrMet: 1.556 ± 0.043	1.869ThrAsn: 1.869 ± 0.048	2.134ThrPro: 2.134 ± 0.051	1.401ThrGln: 1.401 ± 0.04	2.163ThrArg: 2.163 ± 0.048	2.804ThrSer: 2.804 ± 0.062	2.742ThrThr: 2.742 ± 0.068	4.296ThrVal: 4.296 ± 0.079	0.55ThrTrp: 0.55 ± 0.025	1.989ThrTyr: 1.989 ± 0.056	0.0ThrXaa: 0.0 ± 0.0
Val	4.41ValAla: 4.41 ± 0.067	1.217ValCys: 1.217 ± 0.037	3.484ValAsp: 3.484 ± 0.065	4.734ValGlu: 4.734 ± 0.079	3.286ValPhe: 3.286 ± 0.066	4.18ValGly: 4.18 ± 0.074	1.158ValHis: 1.158 ± 0.033	5.203ValIle: 5.203 ± 0.083	4.244ValLys: 4.244 ± 0.069	6.916ValLeu: 6.916 ± 0.095	2.116ValMet: 2.116 ± 0.05	2.552ValAsn: 2.552 ± 0.054	2.662ValPro: 2.662 ± 0.051	1.994ValGln: 1.994 ± 0.045	3.494ValArg: 3.494 ± 0.069	4.448ValSer: 4.448 ± 0.074	4.071ValThr: 4.071 ± 0.073	4.69ValVal: 4.69 ± 0.083	0.69ValTrp: 0.69 ± 0.028	2.68ValTyr: 2.68 ± 0.058	0.0ValXaa: 0.0 ± 0.0
Trp	0.534TrpAla: 0.534 ± 0.022	0.162TrpCys: 0.162 ± 0.013	0.559TrpAsp: 0.559 ± 0.023	0.827TrpGlu: 0.827 ± 0.028	0.442TrpPhe: 0.442 ± 0.02	0.662TrpGly: 0.662 ± 0.03	0.153TrpHis: 0.153 ± 0.014	0.821TrpIle: 0.821 ± 0.039	0.872TrpLys: 0.872 ± 0.034	0.877TrpLeu: 0.877 ± 0.033	0.43TrpMet: 0.43 ± 0.02	0.526TrpAsn: 0.526 ± 0.026	0.234TrpPro: 0.234 ± 0.018	0.318TrpGln: 0.318 ± 0.02	0.444TrpArg: 0.444 ± 0.022	0.486TrpSer: 0.486 ± 0.024	0.435TrpThr: 0.435 ± 0.021	0.492TrpVal: 0.492 ± 0.025	0.108TrpTrp: 0.108 ± 0.01	0.414TrpTyr: 0.414 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.658TyrAla: 2.658 ± 0.056	0.643TyrCys: 0.643 ± 0.029	2.409TyrAsp: 2.409 ± 0.057	3.293TyrGlu: 3.293 ± 0.063	1.934TyrPhe: 1.934 ± 0.073	2.987TyrGly: 2.987 ± 0.056	0.943TyrHis: 0.943 ± 0.032	2.719TyrIle: 2.719 ± 0.058	2.074TyrLys: 2.074 ± 0.043	3.915TyrLeu: 3.915 ± 0.07	1.069TyrMet: 1.069 ± 0.031	1.579TyrAsn: 1.579 ± 0.045	1.572TyrPro: 1.572 ± 0.045	1.593TyrGln: 1.593 ± 0.046	2.292TyrArg: 2.292 ± 0.049	2.116TyrSer: 2.116 ± 0.047	2.237TyrThr: 2.237 ± 0.047	2.558TyrVal: 2.558 ± 0.046	0.394TyrTrp: 0.394 ± 0.023	1.902TyrTyr: 1.902 ± 0.093	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3054 proteins (956250 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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