Amino acid dipepetide frequency for Turkey aviadenovirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.264AlaAla: 5.264 ± 0.908
1.414AlaCys: 1.414 ± 0.383
3.535AlaAsp: 3.535 ± 0.374
4.399AlaGlu: 4.399 ± 0.575
2.435AlaPhe: 2.435 ± 0.472
2.828AlaGly: 2.828 ± 0.541
1.65AlaHis: 1.65 ± 0.353
4.164AlaIle: 4.164 ± 0.534
2.435AlaLys: 2.435 ± 0.435
6.599AlaLeu: 6.599 ± 0.859
1.807AlaMet: 1.807 ± 0.496
2.907AlaAsn: 2.907 ± 0.529
4.321AlaPro: 4.321 ± 0.521
2.671AlaGln: 2.671 ± 0.485
3.692AlaArg: 3.692 ± 0.516
6.128AlaSer: 6.128 ± 0.761
3.457AlaThr: 3.457 ± 0.565
5.028AlaVal: 5.028 ± 0.775
0.55AlaTrp: 0.55 ± 0.188
3.849AlaTyr: 3.849 ± 0.465
0.0AlaXaa: 0.0 ± 0.0
Cys
0.786CysAla: 0.786 ± 0.302
0.393CysCys: 0.393 ± 0.209
1.178CysAsp: 1.178 ± 0.386
0.628CysGlu: 0.628 ± 0.223
0.707CysPhe: 0.707 ± 0.27
1.571CysGly: 1.571 ± 0.446
0.864CysHis: 0.864 ± 0.246
1.1CysIle: 1.1 ± 0.318
0.864CysLys: 0.864 ± 0.27
0.786CysLeu: 0.786 ± 0.234
0.707CysMet: 0.707 ± 0.237
1.021CysAsn: 1.021 ± 0.244
1.178CysPro: 1.178 ± 0.349
0.707CysGln: 0.707 ± 0.291
1.65CysArg: 1.65 ± 0.359
2.121CysSer: 2.121 ± 0.441
0.943CysThr: 0.943 ± 0.272
0.864CysVal: 0.864 ± 0.364
0.393CysTrp: 0.393 ± 0.162
1.021CysTyr: 1.021 ± 0.353
0.0CysXaa: 0.0 ± 0.0
Asp
3.849AspAla: 3.849 ± 0.652
0.864AspCys: 0.864 ± 0.248
2.514AspAsp: 2.514 ± 0.405
3.928AspGlu: 3.928 ± 0.604
2.278AspPhe: 2.278 ± 0.427
3.142AspGly: 3.142 ± 0.57
1.021AspHis: 1.021 ± 0.259
3.378AspIle: 3.378 ± 0.38
1.728AspLys: 1.728 ± 0.353
4.557AspLeu: 4.557 ± 0.518
1.257AspMet: 1.257 ± 0.308
2.357AspAsn: 2.357 ± 0.491
4.399AspPro: 4.399 ± 0.756
2.121AspGln: 2.121 ± 0.412
3.457AspArg: 3.457 ± 0.436
4.949AspSer: 4.949 ± 0.481
2.671AspThr: 2.671 ± 0.522
3.3AspVal: 3.3 ± 0.612
0.628AspTrp: 0.628 ± 0.195
2.593AspTyr: 2.593 ± 0.395
0.0AspXaa: 0.0 ± 0.0
Glu
3.378GluAla: 3.378 ± 0.639
0.628GluCys: 0.628 ± 0.243
4.635GluAsp: 4.635 ± 0.632
6.049GluGlu: 6.049 ± 1.611
1.728GluPhe: 1.728 ± 0.419
3.614GluGly: 3.614 ± 0.476
1.1GluHis: 1.1 ± 0.375
2.278GluIle: 2.278 ± 0.45
2.121GluLys: 2.121 ± 0.445
5.656GluLeu: 5.656 ± 0.782
1.178GluMet: 1.178 ± 0.29
2.75GluAsn: 2.75 ± 0.461
2.828GluPro: 2.828 ± 0.566
2.75GluGln: 2.75 ± 0.474
3.692GluArg: 3.692 ± 0.468
4.557GluSer: 4.557 ± 0.605
3.928GluThr: 3.928 ± 0.811
2.985GluVal: 2.985 ± 0.527
0.943GluTrp: 0.943 ± 0.271
2.278GluTyr: 2.278 ± 0.395
0.0GluXaa: 0.0 ± 0.0
Phe
2.75PheAla: 2.75 ± 0.523
0.707PheCys: 0.707 ± 0.302
2.75PheAsp: 2.75 ± 0.452
1.571PheGlu: 1.571 ± 0.411
1.571PhePhe: 1.571 ± 0.327
1.65PheGly: 1.65 ± 0.511
1.885PheHis: 1.885 ± 0.361
1.414PheIle: 1.414 ± 0.355
2.671PheLys: 2.671 ± 0.438
4.007PheLeu: 4.007 ± 0.663
1.571PheMet: 1.571 ± 0.387
2.435PheAsn: 2.435 ± 0.489
2.75PhePro: 2.75 ± 0.477
1.1PheGln: 1.1 ± 0.282
2.593PheArg: 2.593 ± 0.458
2.671PheSer: 2.671 ± 0.489
2.278PheThr: 2.278 ± 0.348
2.043PheVal: 2.043 ± 0.313
0.786PheTrp: 0.786 ± 0.249
1.885PheTyr: 1.885 ± 0.379
0.0PheXaa: 0.0 ± 0.0
Gly
4.714GlyAla: 4.714 ± 0.753
1.1GlyCys: 1.1 ± 0.375
2.907GlyAsp: 2.907 ± 0.461
4.007GlyGlu: 4.007 ± 0.718
1.964GlyPhe: 1.964 ± 0.387
4.871GlyGly: 4.871 ± 1.004
0.943GlyHis: 0.943 ± 0.336
2.2GlyIle: 2.2 ± 0.405
2.514GlyLys: 2.514 ± 0.681
4.949GlyLeu: 4.949 ± 0.94
1.807GlyMet: 1.807 ± 0.358
1.885GlyAsn: 1.885 ± 0.479
2.828GlyPro: 2.828 ± 0.461
1.493GlyGln: 1.493 ± 0.343
3.535GlyArg: 3.535 ± 0.492
4.949GlySer: 4.949 ± 0.668
4.007GlyThr: 4.007 ± 0.871
5.106GlyVal: 5.106 ± 0.784
1.336GlyTrp: 1.336 ± 0.19
2.357GlyTyr: 2.357 ± 0.368
0.0GlyXaa: 0.0 ± 0.0
His
1.493HisAla: 1.493 ± 0.34
1.021HisCys: 1.021 ± 0.378
1.021HisAsp: 1.021 ± 0.259
1.178HisGlu: 1.178 ± 0.355
1.021HisPhe: 1.021 ± 0.331
1.807HisGly: 1.807 ± 0.444
0.864HisHis: 0.864 ± 0.238
1.414HisIle: 1.414 ± 0.3
0.55HisLys: 0.55 ± 0.213
2.357HisLeu: 2.357 ± 0.447
0.55HisMet: 0.55 ± 0.275
1.493HisAsn: 1.493 ± 0.329
2.121HisPro: 2.121 ± 0.636
1.021HisGln: 1.021 ± 0.379
1.728HisArg: 1.728 ± 0.293
1.493HisSer: 1.493 ± 0.388
1.571HisThr: 1.571 ± 0.445
1.571HisVal: 1.571 ± 0.409
0.157HisTrp: 0.157 ± 0.106
0.943HisTyr: 0.943 ± 0.234
0.0HisXaa: 0.0 ± 0.0
Ile
3.849IleAla: 3.849 ± 0.474
1.414IleCys: 1.414 ± 0.378
2.828IleAsp: 2.828 ± 0.505
1.885IleGlu: 1.885 ± 0.385
1.493IlePhe: 1.493 ± 0.389
2.514IleGly: 2.514 ± 0.45
1.257IleHis: 1.257 ± 0.401
1.807IleIle: 1.807 ± 0.275
2.121IleLys: 2.121 ± 0.474
4.007IleLeu: 4.007 ± 0.6
0.707IleMet: 0.707 ± 0.306
2.514IleAsn: 2.514 ± 0.36
3.142IlePro: 3.142 ± 0.498
1.493IleGln: 1.493 ± 0.303
2.671IleArg: 2.671 ± 0.45
3.3IleSer: 3.3 ± 0.591
3.221IleThr: 3.221 ± 0.554
2.435IleVal: 2.435 ± 0.474
0.628IleTrp: 0.628 ± 0.253
1.493IleTyr: 1.493 ± 0.398
0.0IleXaa: 0.0 ± 0.0
Lys
2.75LysAla: 2.75 ± 0.592
0.786LysCys: 0.786 ± 0.216
2.907LysAsp: 2.907 ± 0.567
1.885LysGlu: 1.885 ± 0.297
2.121LysPhe: 2.121 ± 0.428
2.75LysGly: 2.75 ± 0.645
0.393LysHis: 0.393 ± 0.181
1.728LysIle: 1.728 ± 0.391
2.2LysLys: 2.2 ± 0.565
4.085LysLeu: 4.085 ± 0.638
0.943LysMet: 0.943 ± 0.234
1.728LysAsn: 1.728 ± 0.401
1.964LysPro: 1.964 ± 0.35
1.807LysGln: 1.807 ± 0.491
3.849LysArg: 3.849 ± 0.584
2.043LysSer: 2.043 ± 0.449
2.828LysThr: 2.828 ± 0.417
2.2LysVal: 2.2 ± 0.336
0.628LysTrp: 0.628 ± 0.242
1.571LysTyr: 1.571 ± 0.397
0.0LysXaa: 0.0 ± 0.0
Leu
5.028LeuAla: 5.028 ± 0.552
1.493LeuCys: 1.493 ± 0.326
4.949LeuAsp: 4.949 ± 0.624
4.321LeuGlu: 4.321 ± 0.53
4.085LeuPhe: 4.085 ± 0.506
4.557LeuGly: 4.557 ± 0.571
2.514LeuHis: 2.514 ± 0.561
3.142LeuIle: 3.142 ± 0.61
4.164LeuLys: 4.164 ± 0.668
7.62LeuLeu: 7.62 ± 1.165
2.278LeuMet: 2.278 ± 0.421
3.928LeuAsn: 3.928 ± 0.437
4.871LeuPro: 4.871 ± 0.685
3.928LeuGln: 3.928 ± 0.486
5.813LeuArg: 5.813 ± 0.907
6.363LeuSer: 6.363 ± 0.681
6.678LeuThr: 6.678 ± 0.607
5.106LeuVal: 5.106 ± 0.894
1.336LeuTrp: 1.336 ± 0.334
3.614LeuTyr: 3.614 ± 0.55
0.0LeuXaa: 0.0 ± 0.0
Met
2.2MetAla: 2.2 ± 0.462
0.471MetCys: 0.471 ± 0.203
1.336MetAsp: 1.336 ± 0.301
1.336MetGlu: 1.336 ± 0.301
1.021MetPhe: 1.021 ± 0.303
2.121MetGly: 2.121 ± 0.479
1.021MetHis: 1.021 ± 0.287
1.257MetIle: 1.257 ± 0.331
1.1MetLys: 1.1 ± 0.206
1.807MetLeu: 1.807 ± 0.401
0.628MetMet: 0.628 ± 0.204
1.021MetAsn: 1.021 ± 0.241
1.414MetPro: 1.414 ± 0.281
0.943MetGln: 0.943 ± 0.304
2.043MetArg: 2.043 ± 0.397
2.043MetSer: 2.043 ± 0.455
1.414MetThr: 1.414 ± 0.437
1.414MetVal: 1.414 ± 0.362
0.314MetTrp: 0.314 ± 0.14
1.414MetTyr: 1.414 ± 0.276
0.0MetXaa: 0.0 ± 0.0
Asn
3.3AsnAla: 3.3 ± 0.646
0.943AsnCys: 0.943 ± 0.306
3.064AsnAsp: 3.064 ± 0.5
2.907AsnGlu: 2.907 ± 0.59
1.964AsnPhe: 1.964 ± 0.495
1.571AsnGly: 1.571 ± 0.418
1.178AsnHis: 1.178 ± 0.282
2.514AsnIle: 2.514 ± 0.594
1.807AsnLys: 1.807 ± 0.374
3.535AsnLeu: 3.535 ± 0.658
1.414AsnMet: 1.414 ± 0.45
1.65AsnAsn: 1.65 ± 0.418
3.457AsnPro: 3.457 ± 0.421
1.964AsnGln: 1.964 ± 0.44
3.064AsnArg: 3.064 ± 0.474
2.593AsnSer: 2.593 ± 0.564
3.3AsnThr: 3.3 ± 0.389
2.985AsnVal: 2.985 ± 0.401
0.864AsnTrp: 0.864 ± 0.301
1.807AsnTyr: 1.807 ± 0.407
0.0AsnXaa: 0.0 ± 0.0
Pro
4.399ProAla: 4.399 ± 0.768
0.786ProCys: 0.786 ± 0.2
2.985ProAsp: 2.985 ± 0.407
4.557ProGlu: 4.557 ± 0.622
3.064ProPhe: 3.064 ± 0.638
2.435ProGly: 2.435 ± 0.406
1.728ProHis: 1.728 ± 0.337
2.278ProIle: 2.278 ± 0.378
1.885ProLys: 1.885 ± 0.347
4.399ProLeu: 4.399 ± 0.608
1.728ProMet: 1.728 ± 0.349
2.907ProAsn: 2.907 ± 0.435
6.442ProPro: 6.442 ± 0.924
1.807ProGln: 1.807 ± 0.455
4.557ProArg: 4.557 ± 0.696
4.871ProSer: 4.871 ± 0.761
3.535ProThr: 3.535 ± 0.572
4.242ProVal: 4.242 ± 0.626
0.314ProTrp: 0.314 ± 0.159
2.985ProTyr: 2.985 ± 0.508
0.0ProXaa: 0.0 ± 0.0
Gln
2.828GlnAla: 2.828 ± 0.454
0.55GlnCys: 0.55 ± 0.201
1.493GlnAsp: 1.493 ± 0.362
2.043GlnGlu: 2.043 ± 0.37
1.1GlnPhe: 1.1 ± 0.373
1.964GlnGly: 1.964 ± 0.315
1.021GlnHis: 1.021 ± 0.433
1.65GlnIle: 1.65 ± 0.353
1.728GlnLys: 1.728 ± 0.386
3.692GlnLeu: 3.692 ± 0.594
1.414GlnMet: 1.414 ± 0.251
1.807GlnAsn: 1.807 ± 0.424
2.2GlnPro: 2.2 ± 0.46
2.121GlnGln: 2.121 ± 0.44
2.514GlnArg: 2.514 ± 0.513
3.142GlnSer: 3.142 ± 0.474
2.357GlnThr: 2.357 ± 0.402
1.807GlnVal: 1.807 ± 0.27
0.471GlnTrp: 0.471 ± 0.226
1.885GlnTyr: 1.885 ± 0.5
0.0GlnXaa: 0.0 ± 0.0
Arg
4.085ArgAla: 4.085 ± 0.63
1.257ArgCys: 1.257 ± 0.389
2.2ArgAsp: 2.2 ± 0.59
3.614ArgGlu: 3.614 ± 0.725
3.064ArgPhe: 3.064 ± 0.525
3.771ArgGly: 3.771 ± 0.644
2.2ArgHis: 2.2 ± 0.345
2.907ArgIle: 2.907 ± 0.609
3.064ArgLys: 3.064 ± 0.66
5.656ArgLeu: 5.656 ± 0.895
1.964ArgMet: 1.964 ± 0.351
3.849ArgAsn: 3.849 ± 0.759
3.142ArgPro: 3.142 ± 0.644
2.671ArgGln: 2.671 ± 0.444
6.756ArgArg: 6.756 ± 1.819
5.185ArgSer: 5.185 ± 0.641
3.692ArgThr: 3.692 ± 0.5
3.692ArgVal: 3.692 ± 0.654
1.257ArgTrp: 1.257 ± 0.331
2.985ArgTyr: 2.985 ± 0.437
0.0ArgXaa: 0.0 ± 0.0
Ser
5.578SerAla: 5.578 ± 0.711
1.257SerCys: 1.257 ± 0.329
5.106SerAsp: 5.106 ± 0.671
5.342SerGlu: 5.342 ± 0.629
3.3SerPhe: 3.3 ± 0.56
6.835SerGly: 6.835 ± 0.947
1.807SerHis: 1.807 ± 0.574
3.378SerIle: 3.378 ± 0.533
2.514SerLys: 2.514 ± 0.525
5.813SerLeu: 5.813 ± 0.811
1.65SerMet: 1.65 ± 0.426
3.457SerAsn: 3.457 ± 0.651
3.3SerPro: 3.3 ± 0.508
2.593SerGln: 2.593 ± 0.486
5.106SerArg: 5.106 ± 0.772
6.835SerSer: 6.835 ± 0.893
4.792SerThr: 4.792 ± 0.825
5.342SerVal: 5.342 ± 0.812
0.864SerTrp: 0.864 ± 0.277
2.278SerTyr: 2.278 ± 0.353
0.0SerXaa: 0.0 ± 0.0
Thr
5.185ThrAla: 5.185 ± 0.743
1.336ThrCys: 1.336 ± 0.381
2.75ThrAsp: 2.75 ± 0.442
2.593ThrGlu: 2.593 ± 0.416
2.75ThrPhe: 2.75 ± 0.603
4.871ThrGly: 4.871 ± 0.735
1.493ThrHis: 1.493 ± 0.336
2.435ThrIle: 2.435 ± 0.384
1.885ThrLys: 1.885 ± 0.344
5.656ThrLeu: 5.656 ± 0.759
1.257ThrMet: 1.257 ± 0.279
2.907ThrAsn: 2.907 ± 0.609
3.457ThrPro: 3.457 ± 0.737
1.964ThrGln: 1.964 ± 0.357
3.221ThrArg: 3.221 ± 0.481
5.656ThrSer: 5.656 ± 0.74
4.792ThrThr: 4.792 ± 1.043
4.478ThrVal: 4.478 ± 0.665
0.471ThrTrp: 0.471 ± 0.16
3.221ThrTyr: 3.221 ± 0.549
0.0ThrXaa: 0.0 ± 0.0
Val
4.085ValAla: 4.085 ± 0.543
1.1ValCys: 1.1 ± 0.275
2.985ValAsp: 2.985 ± 0.481
3.928ValGlu: 3.928 ± 0.7
2.671ValPhe: 2.671 ± 0.468
3.142ValGly: 3.142 ± 0.623
0.943ValHis: 0.943 ± 0.22
3.064ValIle: 3.064 ± 0.528
3.142ValLys: 3.142 ± 0.565
6.049ValLeu: 6.049 ± 0.699
1.65ValMet: 1.65 ± 0.479
2.75ValAsn: 2.75 ± 0.574
4.871ValPro: 4.871 ± 0.909
2.907ValGln: 2.907 ± 0.697
3.928ValArg: 3.928 ± 0.567
4.557ValSer: 4.557 ± 0.89
4.478ValThr: 4.478 ± 0.549
4.321ValVal: 4.321 ± 0.672
1.1ValTrp: 1.1 ± 0.358
2.278ValTyr: 2.278 ± 0.453
0.0ValXaa: 0.0 ± 0.0
Trp
1.021TrpAla: 1.021 ± 0.265
0.628TrpCys: 0.628 ± 0.271
1.021TrpAsp: 1.021 ± 0.307
0.55TrpGlu: 0.55 ± 0.159
0.707TrpPhe: 0.707 ± 0.225
0.786TrpGly: 0.786 ± 0.242
0.314TrpHis: 0.314 ± 0.157
0.864TrpIle: 0.864 ± 0.24
0.786TrpLys: 0.786 ± 0.308
1.021TrpLeu: 1.021 ± 0.28
0.236TrpMet: 0.236 ± 0.176
0.864TrpAsn: 0.864 ± 0.235
0.393TrpPro: 0.393 ± 0.283
0.628TrpGln: 0.628 ± 0.258
1.021TrpArg: 1.021 ± 0.285
0.864TrpSer: 0.864 ± 0.245
0.864TrpThr: 0.864 ± 0.238
0.943TrpVal: 0.943 ± 0.273
0.314TrpTrp: 0.314 ± 0.164
0.55TrpTyr: 0.55 ± 0.175
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.593TyrAla: 2.593 ± 0.485
1.336TyrCys: 1.336 ± 0.322
2.828TyrAsp: 2.828 ± 0.461
2.357TyrGlu: 2.357 ± 0.337
2.043TyrPhe: 2.043 ± 0.504
2.671TyrGly: 2.671 ± 0.489
1.178TyrHis: 1.178 ± 0.357
1.807TyrIle: 1.807 ± 0.372
1.885TyrLys: 1.885 ± 0.41
3.535TyrLeu: 3.535 ± 0.598
1.493TyrMet: 1.493 ± 0.427
1.65TyrAsn: 1.65 ± 0.336
2.828TyrPro: 2.828 ± 0.482
1.1TyrGln: 1.1 ± 0.296
2.121TyrArg: 2.121 ± 0.455
2.828TyrSer: 2.828 ± 0.543
1.571TyrThr: 1.571 ± 0.326
4.085TyrVal: 4.085 ± 0.489
1.1TyrTrp: 1.1 ± 0.308
1.885TyrTyr: 1.885 ± 0.477
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 33 proteins (12730 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski