Amino acid dipepetide frequency for Cordyceps confragosa (Lecanicillium lecanii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.266AlaAla: 11.266 ± 0.084	1.137AlaCys: 1.137 ± 0.018	4.988AlaAsp: 4.988 ± 0.039	5.401AlaGlu: 5.401 ± 0.043	3.308AlaPhe: 3.308 ± 0.036	6.367AlaGly: 6.367 ± 0.048	1.943AlaHis: 1.943 ± 0.021	4.371AlaIle: 4.371 ± 0.037	4.512AlaLys: 4.512 ± 0.042	8.186AlaLeu: 8.186 ± 0.051	2.277AlaMet: 2.277 ± 0.025	3.165AlaAsn: 3.165 ± 0.026	5.069AlaPro: 5.069 ± 0.045	3.751AlaGln: 3.751 ± 0.033	5.262AlaArg: 5.262 ± 0.042	7.867AlaSer: 7.867 ± 0.052	5.779AlaThr: 5.779 ± 0.041	5.982AlaVal: 5.982 ± 0.041	1.23AlaTrp: 1.23 ± 0.018	2.193AlaTyr: 2.193 ± 0.022	0.003AlaXaa: 0.003 ± 0.001
Cys	1.047CysAla: 1.047 ± 0.018	0.245CysCys: 0.245 ± 0.009	0.716CysAsp: 0.716 ± 0.017	0.575CysGlu: 0.575 ± 0.013	0.562CysPhe: 0.562 ± 0.012	0.972CysGly: 0.972 ± 0.021	0.327CysHis: 0.327 ± 0.009	0.726CysIle: 0.726 ± 0.013	0.527CysLys: 0.527 ± 0.012	1.266CysLeu: 1.266 ± 0.021	0.259CysMet: 0.259 ± 0.008	0.442CysAsn: 0.442 ± 0.012	0.655CysPro: 0.655 ± 0.015	0.46CysGln: 0.46 ± 0.011	0.799CysArg: 0.799 ± 0.017	0.912CysSer: 0.912 ± 0.016	0.69CysThr: 0.69 ± 0.014	0.801CysVal: 0.801 ± 0.015	0.191CysTrp: 0.191 ± 0.008	0.334CysTyr: 0.334 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	5.596AspAla: 5.596 ± 0.043	0.677AspCys: 0.677 ± 0.014	4.713AspAsp: 4.713 ± 0.05	4.678AspGlu: 4.678 ± 0.048	2.269AspPhe: 2.269 ± 0.021	4.587AspGly: 4.587 ± 0.042	1.231AspHis: 1.231 ± 0.018	2.953AspIle: 2.953 ± 0.031	2.696AspLys: 2.696 ± 0.031	4.861AspLeu: 4.861 ± 0.037	1.469AspMet: 1.469 ± 0.017	1.935AspAsn: 1.935 ± 0.024	2.938AspPro: 2.938 ± 0.027	1.832AspGln: 1.832 ± 0.023	3.021AspArg: 3.021 ± 0.034	4.222AspSer: 4.222 ± 0.039	2.958AspThr: 2.958 ± 0.026	3.857AspVal: 3.857 ± 0.036	0.867AspTrp: 0.867 ± 0.017	1.555AspTyr: 1.555 ± 0.02	0.002AspXaa: 0.002 ± 0.001
Glu	5.634GluAla: 5.634 ± 0.044	0.611GluCys: 0.611 ± 0.011	4.087GluAsp: 4.087 ± 0.042	4.852GluGlu: 4.852 ± 0.06	1.929GluPhe: 1.929 ± 0.022	3.28GluGly: 3.28 ± 0.029	1.423GluHis: 1.423 ± 0.02	2.744GluIle: 2.744 ± 0.034	3.397GluLys: 3.397 ± 0.037	5.271GluLeu: 5.271 ± 0.047	1.479GluMet: 1.479 ± 0.018	2.179GluAsn: 2.179 ± 0.023	2.763GluPro: 2.763 ± 0.034	2.553GluGln: 2.553 ± 0.028	3.666GluArg: 3.666 ± 0.034	4.126GluSer: 4.126 ± 0.034	3.446GluThr: 3.446 ± 0.032	3.249GluVal: 3.249 ± 0.03	0.808GluTrp: 0.808 ± 0.014	1.591GluTyr: 1.591 ± 0.021	0.001GluXaa: 0.001 ± 0.0
Phe	3.35PheAla: 3.35 ± 0.034	0.569PheCys: 0.569 ± 0.012	2.378PheAsp: 2.378 ± 0.023	2.079PheGlu: 2.079 ± 0.022	1.665PhePhe: 1.665 ± 0.024	2.882PheGly: 2.882 ± 0.036	0.877PheHis: 0.877 ± 0.015	1.712PheIle: 1.712 ± 0.02	1.499PheLys: 1.499 ± 0.019	3.421PheLeu: 3.421 ± 0.035	0.842PheMet: 0.842 ± 0.017	1.4PheAsn: 1.4 ± 0.019	1.821PhePro: 1.821 ± 0.023	1.388PheGln: 1.388 ± 0.021	1.971PheArg: 1.971 ± 0.022	2.962PheSer: 2.962 ± 0.029	2.094PheThr: 2.094 ± 0.025	2.452PheVal: 2.452 ± 0.025	0.661PheTrp: 0.661 ± 0.013	1.093PheTyr: 1.093 ± 0.019	0.001PheXaa: 0.001 ± 0.001
Gly	5.855GlyAla: 5.855 ± 0.05	0.861GlyCys: 0.861 ± 0.017	3.796GlyAsp: 3.796 ± 0.034	3.525GlyGlu: 3.525 ± 0.03	2.711GlyPhe: 2.711 ± 0.029	5.716GlyGly: 5.716 ± 0.061	1.756GlyHis: 1.756 ± 0.028	3.443GlyIle: 3.443 ± 0.03	3.506GlyLys: 3.506 ± 0.033	5.985GlyLeu: 5.985 ± 0.041	1.627GlyMet: 1.627 ± 0.023	2.58GlyAsn: 2.58 ± 0.032	3.196GlyPro: 3.196 ± 0.032	2.687GlyGln: 2.687 ± 0.025	4.215GlyArg: 4.215 ± 0.041	5.706GlySer: 5.706 ± 0.048	3.89GlyThr: 3.89 ± 0.035	4.251GlyVal: 4.251 ± 0.037	1.118GlyTrp: 1.118 ± 0.018	2.078GlyTyr: 2.078 ± 0.027	0.003GlyXaa: 0.003 ± 0.001
His	2.005HisAla: 2.005 ± 0.022	0.339HisCys: 0.339 ± 0.009	1.428HisAsp: 1.428 ± 0.021	1.332HisGlu: 1.332 ± 0.021	0.921HisPhe: 0.921 ± 0.016	1.853HisGly: 1.853 ± 0.023	0.888HisHis: 0.888 ± 0.021	1.184HisIle: 1.184 ± 0.017	0.927HisLys: 0.927 ± 0.015	2.158HisLeu: 2.158 ± 0.026	0.557HisMet: 0.557 ± 0.013	0.868HisAsn: 0.868 ± 0.015	1.485HisPro: 1.485 ± 0.023	0.991HisGln: 0.991 ± 0.018	1.565HisArg: 1.565 ± 0.022	1.837HisSer: 1.837 ± 0.024	1.217HisThr: 1.217 ± 0.017	1.495HisVal: 1.495 ± 0.019	0.335HisTrp: 0.335 ± 0.009	0.686HisTyr: 0.686 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.33IleAla: 4.33 ± 0.028	0.734IleCys: 0.734 ± 0.014	2.848IleAsp: 2.848 ± 0.031	2.685IleGlu: 2.685 ± 0.031	1.925IlePhe: 1.925 ± 0.023	3.125IleGly: 3.125 ± 0.033	1.118IleHis: 1.118 ± 0.017	2.391IleIle: 2.391 ± 0.03	2.11IleLys: 2.11 ± 0.027	4.385IleLeu: 4.385 ± 0.04	1.092IleMet: 1.092 ± 0.018	1.671IleAsn: 1.671 ± 0.021	2.684IlePro: 2.684 ± 0.025	1.783IleGln: 1.783 ± 0.019	2.694IleArg: 2.694 ± 0.028	3.602IleSer: 3.602 ± 0.03	2.649IleThr: 2.649 ± 0.027	3.24IleVal: 3.24 ± 0.032	0.678IleTrp: 0.678 ± 0.014	1.289IleTyr: 1.289 ± 0.018	0.001IleXaa: 0.001 ± 0.0
Lys	4.436LysAla: 4.436 ± 0.04	0.506LysCys: 0.506 ± 0.011	2.85LysAsp: 2.85 ± 0.034	3.041LysGlu: 3.041 ± 0.033	1.511LysPhe: 1.511 ± 0.022	2.77LysGly: 2.77 ± 0.028	1.144LysHis: 1.144 ± 0.018	2.172LysIle: 2.172 ± 0.025	3.276LysLys: 3.276 ± 0.057	4.238LysLeu: 4.238 ± 0.036	1.094LysMet: 1.094 ± 0.015	1.74LysAsn: 1.74 ± 0.021	2.684LysPro: 2.684 ± 0.029	2.012LysGln: 2.012 ± 0.026	3.297LysArg: 3.297 ± 0.035	3.582LysSer: 3.582 ± 0.031	2.995LysThr: 2.995 ± 0.029	2.728LysVal: 2.728 ± 0.028	0.663LysTrp: 0.663 ± 0.012	1.331LysTyr: 1.331 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.395LeuAla: 8.395 ± 0.055	1.272LeuCys: 1.272 ± 0.02	5.31LeuAsp: 5.31 ± 0.036	5.246LeuGlu: 5.246 ± 0.045	3.377LeuPhe: 3.377 ± 0.036	5.938LeuGly: 5.938 ± 0.043	2.286LeuHis: 2.286 ± 0.028	3.744LeuIle: 3.744 ± 0.043	4.009LeuLys: 4.009 ± 0.034	8.483LeuLeu: 8.483 ± 0.076	1.788LeuMet: 1.788 ± 0.023	2.965LeuAsn: 2.965 ± 0.028	5.377LeuPro: 5.377 ± 0.037	3.965LeuGln: 3.965 ± 0.04	5.881LeuArg: 5.881 ± 0.053	7.134LeuSer: 7.134 ± 0.048	4.692LeuThr: 4.692 ± 0.036	5.588LeuVal: 5.588 ± 0.044	1.192LeuTrp: 1.192 ± 0.02	2.287LeuTyr: 2.287 ± 0.024	0.002LeuXaa: 0.002 ± 0.001
Met	2.473MetAla: 2.473 ± 0.026	0.255MetCys: 0.255 ± 0.008	1.356MetAsp: 1.356 ± 0.019	1.315MetGlu: 1.315 ± 0.021	0.768MetPhe: 0.768 ± 0.016	1.498MetGly: 1.498 ± 0.021	0.528MetHis: 0.528 ± 0.011	0.958MetIle: 0.958 ± 0.017	0.992MetLys: 0.992 ± 0.014	2.013MetLeu: 2.013 ± 0.024	0.62MetMet: 0.62 ± 0.012	0.818MetAsn: 0.818 ± 0.014	1.423MetPro: 1.423 ± 0.022	0.97MetGln: 0.97 ± 0.015	1.393MetArg: 1.393 ± 0.018	1.944MetSer: 1.944 ± 0.022	1.397MetThr: 1.397 ± 0.018	1.344MetVal: 1.344 ± 0.019	0.27MetTrp: 0.27 ± 0.008	0.558MetTyr: 0.558 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.239AsnAla: 3.239 ± 0.033	0.447AsnCys: 0.447 ± 0.011	1.982AsnAsp: 1.982 ± 0.021	1.934AsnGlu: 1.934 ± 0.024	1.344AsnPhe: 1.344 ± 0.02	3.015AsnGly: 3.015 ± 0.036	0.81AsnHis: 0.81 ± 0.013	1.943AsnIle: 1.943 ± 0.023	1.608AsnLys: 1.608 ± 0.022	3.114AsnLeu: 3.114 ± 0.029	0.908AsnMet: 0.908 ± 0.015	1.42AsnAsn: 1.42 ± 0.02	2.137AsnPro: 2.137 ± 0.027	1.282AsnGln: 1.282 ± 0.023	1.909AsnArg: 1.909 ± 0.023	2.622AsnSer: 2.622 ± 0.027	2.051AsnThr: 2.051 ± 0.027	2.346AsnVal: 2.346 ± 0.028	0.535AsnTrp: 0.535 ± 0.013	1.017AsnTyr: 1.017 ± 0.017	0.001AsnXaa: 0.001 ± 0.001
Pro	5.548ProAla: 5.548 ± 0.044	0.535ProCys: 0.535 ± 0.013	3.13ProAsp: 3.13 ± 0.032	3.568ProGlu: 3.568 ± 0.032	1.982ProPhe: 1.982 ± 0.02	3.819ProGly: 3.819 ± 0.039	1.216ProHis: 1.216 ± 0.018	2.311ProIle: 2.311 ± 0.025	2.63ProLys: 2.63 ± 0.027	4.564ProLeu: 4.564 ± 0.033	1.133ProMet: 1.133 ± 0.019	2.039ProAsn: 2.039 ± 0.025	4.605ProPro: 4.605 ± 0.072	2.397ProGln: 2.397 ± 0.031	3.444ProArg: 3.444 ± 0.035	5.428ProSer: 5.428 ± 0.055	3.66ProThr: 3.66 ± 0.039	3.523ProVal: 3.523 ± 0.034	0.701ProTrp: 0.701 ± 0.014	1.367ProTyr: 1.367 ± 0.019	0.003ProXaa: 0.003 ± 0.001
Gln	3.689GlnAla: 3.689 ± 0.034	0.452GlnCys: 0.452 ± 0.011	2.243GlnAsp: 2.243 ± 0.023	2.312GlnGlu: 2.312 ± 0.026	1.331GlnPhe: 1.331 ± 0.017	2.43GlnGly: 2.43 ± 0.028	1.171GlnHis: 1.171 ± 0.02	1.827GlnIle: 1.827 ± 0.021	1.951GlnLys: 1.951 ± 0.025	3.678GlnLeu: 3.678 ± 0.039	0.951GlnMet: 0.951 ± 0.018	1.505GlnAsn: 1.505 ± 0.02	2.56GlnPro: 2.56 ± 0.028	2.675GlnGln: 2.675 ± 0.059	2.794GlnArg: 2.794 ± 0.029	3.156GlnSer: 3.156 ± 0.038	2.302GlnThr: 2.302 ± 0.026	2.216GlnVal: 2.216 ± 0.023	0.564GlnTrp: 0.564 ± 0.013	1.156GlnTyr: 1.156 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	5.076ArgAla: 5.076 ± 0.037	0.758ArgCys: 0.758 ± 0.016	3.565ArgAsp: 3.565 ± 0.04	3.582ArgGlu: 3.582 ± 0.037	2.167ArgPhe: 2.167 ± 0.024	3.801ArgGly: 3.801 ± 0.042	1.688ArgHis: 1.688 ± 0.022	2.883ArgIle: 2.883 ± 0.027	3.291ArgLys: 3.291 ± 0.036	5.577ArgLeu: 5.577 ± 0.037	1.338ArgMet: 1.338 ± 0.019	2.203ArgAsn: 2.203 ± 0.026	3.504ArgPro: 3.504 ± 0.034	2.825ArgGln: 2.825 ± 0.029	5.269ArgArg: 5.269 ± 0.048	4.768ArgSer: 4.768 ± 0.042	3.213ArgThr: 3.213 ± 0.034	3.36ArgVal: 3.36 ± 0.028	0.886ArgTrp: 0.886 ± 0.016	1.618ArgTyr: 1.618 ± 0.02	0.002ArgXaa: 0.002 ± 0.001
Ser	7.181SerAla: 7.181 ± 0.055	0.904SerCys: 0.904 ± 0.017	4.276SerAsp: 4.276 ± 0.04	3.902SerGlu: 3.902 ± 0.036	2.989SerPhe: 2.989 ± 0.027	5.519SerGly: 5.519 ± 0.044	1.949SerHis: 1.949 ± 0.025	3.83SerIle: 3.83 ± 0.037	3.769SerLys: 3.769 ± 0.035	7.047SerLeu: 7.047 ± 0.044	1.807SerMet: 1.807 ± 0.024	2.906SerAsn: 2.906 ± 0.032	5.109SerPro: 5.109 ± 0.054	3.258SerGln: 3.258 ± 0.032	5.083SerArg: 5.083 ± 0.042	8.261SerSer: 8.261 ± 0.073	5.246SerThr: 5.246 ± 0.043	4.652SerVal: 4.652 ± 0.035	1.099SerTrp: 1.099 ± 0.016	1.959SerTyr: 1.959 ± 0.021	0.002SerXaa: 0.002 ± 0.001
Thr	5.615ThrAla: 5.615 ± 0.033	0.729ThrCys: 0.729 ± 0.013	2.867ThrAsp: 2.867 ± 0.024	3.087ThrGlu: 3.087 ± 0.031	2.182ThrPhe: 2.182 ± 0.027	4.045ThrGly: 4.045 ± 0.035	1.255ThrHis: 1.255 ± 0.02	2.955ThrIle: 2.955 ± 0.032	2.67ThrLys: 2.67 ± 0.028	5.139ThrLeu: 5.139 ± 0.036	1.292ThrMet: 1.292 ± 0.02	1.98ThrAsn: 1.98 ± 0.026	4.042ThrPro: 4.042 ± 0.043	2.071ThrGln: 2.071 ± 0.024	3.117ThrArg: 3.117 ± 0.031	5.065ThrSer: 5.065 ± 0.044	4.139ThrThr: 4.139 ± 0.045	3.776ThrVal: 3.776 ± 0.034	0.792ThrTrp: 0.792 ± 0.015	1.508ThrTyr: 1.508 ± 0.019	0.002ThrXaa: 0.002 ± 0.001
Val	5.925ValAla: 5.925 ± 0.044	0.864ValCys: 0.864 ± 0.013	3.862ValAsp: 3.862 ± 0.033	3.719ValGlu: 3.719 ± 0.035	2.489ValPhe: 2.489 ± 0.026	4.01ValGly: 4.01 ± 0.036	1.393ValHis: 1.393 ± 0.019	2.871ValIle: 2.871 ± 0.026	2.823ValLys: 2.823 ± 0.026	5.703ValLeu: 5.703 ± 0.05	1.355ValMet: 1.355 ± 0.018	2.172ValAsn: 2.172 ± 0.027	3.556ValPro: 3.556 ± 0.031	2.441ValGln: 2.441 ± 0.024	3.498ValArg: 3.498 ± 0.029	4.558ValSer: 4.558 ± 0.036	3.494ValThr: 3.494 ± 0.031	4.364ValVal: 4.364 ± 0.042	0.872ValTrp: 0.872 ± 0.017	1.701ValTyr: 1.701 ± 0.02	0.001ValXaa: 0.001 ± 0.001
Trp	1.181TrpAla: 1.181 ± 0.017	0.195TrpCys: 0.195 ± 0.006	0.878TrpAsp: 0.878 ± 0.016	0.779TrpGlu: 0.779 ± 0.015	0.519TrpPhe: 0.519 ± 0.01	0.872TrpGly: 0.872 ± 0.017	0.358TrpHis: 0.358 ± 0.009	0.717TrpIle: 0.717 ± 0.015	0.733TrpLys: 0.733 ± 0.014	1.357TrpLeu: 1.357 ± 0.022	0.363TrpMet: 0.363 ± 0.009	0.591TrpAsn: 0.591 ± 0.012	0.622TrpPro: 0.622 ± 0.015	0.602TrpGln: 0.602 ± 0.011	0.945TrpArg: 0.945 ± 0.016	1.022TrpSer: 1.022 ± 0.017	0.886TrpThr: 0.886 ± 0.016	0.848TrpVal: 0.848 ± 0.017	0.281TrpTrp: 0.281 ± 0.009	0.427TrpTyr: 0.427 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.21TyrAla: 2.21 ± 0.023	0.414TyrCys: 0.414 ± 0.01	1.643TyrAsp: 1.643 ± 0.023	1.477TyrGlu: 1.477 ± 0.021	1.167TyrPhe: 1.167 ± 0.017	2.004TyrGly: 2.004 ± 0.027	0.709TyrHis: 0.709 ± 0.013	1.3TyrIle: 1.3 ± 0.019	1.148TyrLys: 1.148 ± 0.016	2.485TyrLeu: 2.485 ± 0.03	0.643TyrMet: 0.643 ± 0.013	1.084TyrAsn: 1.084 ± 0.017	1.368TyrPro: 1.368 ± 0.02	1.019TyrGln: 1.019 ± 0.015	1.548TyrArg: 1.548 ± 0.02	1.973TyrSer: 1.973 ± 0.024	1.528TyrThr: 1.528 ± 0.02	1.596TyrVal: 1.596 ± 0.022	0.433TyrTrp: 0.433 ± 0.009	0.897TyrTyr: 0.897 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.001	0.001XaaGlu: 0.001 ± 0.001	0.001XaaPhe: 0.001 ± 0.001	0.003XaaGly: 0.003 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.002XaaLeu: 0.002 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.003XaaPro: 0.003 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.002XaaSer: 0.002 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.003XaaVal: 0.003 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	1.615XaaXaa: 1.615 ± 0.167

Statistics based on 8125 proteins (4131730 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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