Amino acid dipepetide frequency for Mount Mabu Lophuromys virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.17AlaAla: 3.17 ± 0.576
0.932AlaCys: 0.932 ± 0.425
2.051AlaAsp: 2.051 ± 1.003
2.984AlaGlu: 2.984 ± 0.86
1.492AlaPhe: 1.492 ± 0.278
3.73AlaGly: 3.73 ± 1.497
0.746AlaHis: 0.746 ± 0.478
4.103AlaIle: 4.103 ± 1.084
1.492AlaLys: 1.492 ± 0.553
5.035AlaLeu: 5.035 ± 1.55
1.492AlaMet: 1.492 ± 0.269
1.305AlaAsn: 1.305 ± 0.489
2.051AlaPro: 2.051 ± 1.056
3.357AlaGln: 3.357 ± 0.623
2.611AlaArg: 2.611 ± 0.812
3.543AlaSer: 3.543 ± 0.791
2.611AlaThr: 2.611 ± 0.73
3.73AlaVal: 3.73 ± 1.006
1.119AlaTrp: 1.119 ± 0.241
2.051AlaTyr: 2.051 ± 0.469
0.0AlaXaa: 0.0 ± 0.0
Cys
0.373CysAla: 0.373 ± 0.447
0.559CysCys: 0.559 ± 0.442
0.559CysAsp: 0.559 ± 0.313
0.559CysGlu: 0.559 ± 0.299
0.746CysPhe: 0.746 ± 0.316
0.932CysGly: 0.932 ± 0.358
0.559CysHis: 0.559 ± 0.359
0.746CysIle: 0.746 ± 0.216
0.559CysLys: 0.559 ± 0.404
1.305CysLeu: 1.305 ± 0.3
0.559CysMet: 0.559 ± 0.224
0.559CysAsn: 0.559 ± 0.259
0.932CysPro: 0.932 ± 0.494
0.932CysGln: 0.932 ± 0.493
1.119CysArg: 1.119 ± 0.562
0.932CysSer: 0.932 ± 0.213
0.746CysThr: 0.746 ± 0.339
0.373CysVal: 0.373 ± 0.202
0.0CysTrp: 0.0 ± 0.0
1.119CysTyr: 1.119 ± 0.527
0.0CysXaa: 0.0 ± 0.0
Asp
2.797AspAla: 2.797 ± 0.422
1.119AspCys: 1.119 ± 0.627
5.968AspAsp: 5.968 ± 0.899
5.222AspGlu: 5.222 ± 0.959
2.611AspPhe: 2.611 ± 0.853
1.678AspGly: 1.678 ± 0.816
1.865AspHis: 1.865 ± 0.273
3.17AspIle: 3.17 ± 0.471
3.543AspLys: 3.543 ± 0.594
5.781AspLeu: 5.781 ± 0.847
1.119AspMet: 1.119 ± 0.316
2.984AspAsn: 2.984 ± 0.619
4.662AspPro: 4.662 ± 0.532
1.492AspGln: 1.492 ± 0.742
3.357AspArg: 3.357 ± 0.91
3.543AspSer: 3.543 ± 0.655
3.17AspThr: 3.17 ± 0.412
3.17AspVal: 3.17 ± 0.591
0.373AspTrp: 0.373 ± 0.239
2.611AspTyr: 2.611 ± 0.993
0.0AspXaa: 0.0 ± 0.0
Glu
2.611GluAla: 2.611 ± 0.65
1.119GluCys: 1.119 ± 0.354
3.357GluAsp: 3.357 ± 0.971
3.73GluGlu: 3.73 ± 0.855
1.865GluPhe: 1.865 ± 0.599
4.289GluGly: 4.289 ± 1.021
0.559GluHis: 0.559 ± 0.248
5.595GluIle: 5.595 ± 1.181
3.17GluLys: 3.17 ± 0.824
2.984GluLeu: 2.984 ± 0.619
1.678GluMet: 1.678 ± 0.471
2.984GluAsn: 2.984 ± 0.829
1.492GluPro: 1.492 ± 0.46
3.17GluGln: 3.17 ± 0.907
2.051GluArg: 2.051 ± 0.582
4.849GluSer: 4.849 ± 1.796
2.611GluThr: 2.611 ± 0.456
4.662GluVal: 4.662 ± 0.655
0.559GluTrp: 0.559 ± 0.245
1.865GluTyr: 1.865 ± 0.581
0.0GluXaa: 0.0 ± 0.0
Phe
2.238PheAla: 2.238 ± 0.927
1.119PheCys: 1.119 ± 0.538
2.797PheAsp: 2.797 ± 0.923
2.424PheGlu: 2.424 ± 0.945
1.492PhePhe: 1.492 ± 0.633
2.611PheGly: 2.611 ± 0.618
0.559PheHis: 0.559 ± 0.234
1.678PheIle: 1.678 ± 0.527
2.611PheLys: 2.611 ± 0.632
3.543PheLeu: 3.543 ± 0.788
1.305PheMet: 1.305 ± 0.565
2.611PheAsn: 2.611 ± 0.494
1.492PhePro: 1.492 ± 0.316
1.119PheGln: 1.119 ± 0.454
2.238PheArg: 2.238 ± 0.735
2.984PheSer: 2.984 ± 0.552
0.932PheThr: 0.932 ± 0.409
1.678PheVal: 1.678 ± 0.388
0.746PheTrp: 0.746 ± 0.329
0.186PheTyr: 0.186 ± 0.12
0.0PheXaa: 0.0 ± 0.0
Gly
3.543GlyAla: 3.543 ± 1.26
1.119GlyCys: 1.119 ± 0.632
2.797GlyAsp: 2.797 ± 0.469
2.611GlyGlu: 2.611 ± 0.927
2.424GlyPhe: 2.424 ± 0.696
4.662GlyGly: 4.662 ± 1.638
1.305GlyHis: 1.305 ± 0.338
4.289GlyIle: 4.289 ± 1.817
3.916GlyLys: 3.916 ± 1.273
4.103GlyLeu: 4.103 ± 0.966
1.678GlyMet: 1.678 ± 0.69
4.476GlyAsn: 4.476 ± 0.576
1.865GlyPro: 1.865 ± 0.489
1.865GlyGln: 1.865 ± 0.374
3.916GlyArg: 3.916 ± 0.754
4.476GlySer: 4.476 ± 1.191
3.17GlyThr: 3.17 ± 0.891
3.357GlyVal: 3.357 ± 1.211
0.559GlyTrp: 0.559 ± 0.289
3.357GlyTyr: 3.357 ± 0.886
0.0GlyXaa: 0.0 ± 0.0
His
0.559HisAla: 0.559 ± 0.316
0.186HisCys: 0.186 ± 0.12
0.932HisAsp: 0.932 ± 0.293
1.305HisGlu: 1.305 ± 0.489
0.559HisPhe: 0.559 ± 0.22
0.559HisGly: 0.559 ± 0.243
0.559HisHis: 0.559 ± 0.313
1.492HisIle: 1.492 ± 0.58
0.932HisLys: 0.932 ± 0.425
1.865HisLeu: 1.865 ± 0.827
0.373HisMet: 0.373 ± 0.239
1.492HisAsn: 1.492 ± 0.586
1.305HisPro: 1.305 ± 0.375
0.373HisGln: 0.373 ± 0.159
1.119HisArg: 1.119 ± 0.324
2.238HisSer: 2.238 ± 0.569
0.746HisThr: 0.746 ± 0.312
1.305HisVal: 1.305 ± 0.256
0.373HisTrp: 0.373 ± 0.271
0.186HisTyr: 0.186 ± 0.12
0.0HisXaa: 0.0 ± 0.0
Ile
3.73IleAla: 3.73 ± 0.964
1.119IleCys: 1.119 ± 0.575
3.916IleAsp: 3.916 ± 1.036
3.543IleGlu: 3.543 ± 0.599
2.424IlePhe: 2.424 ± 0.465
4.103IleGly: 4.103 ± 0.891
0.746IleHis: 0.746 ± 0.332
6.527IleIle: 6.527 ± 1.569
5.222IleLys: 5.222 ± 0.473
8.952IleLeu: 8.952 ± 1.02
1.492IleMet: 1.492 ± 0.454
4.476IleAsn: 4.476 ± 0.743
4.476IlePro: 4.476 ± 0.872
4.289IleGln: 4.289 ± 1.216
2.797IleArg: 2.797 ± 0.85
6.527IleSer: 6.527 ± 1.406
5.968IleThr: 5.968 ± 0.862
4.289IleVal: 4.289 ± 0.664
0.373IleTrp: 0.373 ± 0.285
3.73IleTyr: 3.73 ± 0.831
0.0IleXaa: 0.0 ± 0.0
Lys
4.849LysAla: 4.849 ± 1.491
0.373LysCys: 0.373 ± 0.239
4.849LysAsp: 4.849 ± 0.645
4.103LysGlu: 4.103 ± 0.813
2.238LysPhe: 2.238 ± 0.565
2.984LysGly: 2.984 ± 1.195
1.119LysHis: 1.119 ± 0.438
5.035LysIle: 5.035 ± 0.646
4.289LysLys: 4.289 ± 0.768
6.527LysLeu: 6.527 ± 1.048
1.119LysMet: 1.119 ± 0.4
2.611LysAsn: 2.611 ± 0.425
1.865LysPro: 1.865 ± 0.409
1.492LysGln: 1.492 ± 0.383
3.543LysArg: 3.543 ± 0.577
5.968LysSer: 5.968 ± 0.495
2.424LysThr: 2.424 ± 0.607
3.916LysVal: 3.916 ± 1.045
0.373LysTrp: 0.373 ± 0.239
2.051LysTyr: 2.051 ± 0.73
0.0LysXaa: 0.0 ± 0.0
Leu
4.289LeuAla: 4.289 ± 1.304
0.932LeuCys: 0.932 ± 0.278
6.154LeuAsp: 6.154 ± 0.504
4.662LeuGlu: 4.662 ± 1.081
3.543LeuPhe: 3.543 ± 1.131
6.714LeuGly: 6.714 ± 0.791
2.238LeuHis: 2.238 ± 0.457
6.9LeuIle: 6.9 ± 1.299
5.968LeuLys: 5.968 ± 1.631
7.646LeuLeu: 7.646 ± 1.378
2.984LeuMet: 2.984 ± 0.765
5.595LeuAsn: 5.595 ± 1.054
2.238LeuPro: 2.238 ± 0.491
4.103LeuGln: 4.103 ± 0.535
4.289LeuArg: 4.289 ± 1.186
10.63LeuSer: 10.63 ± 1.305
7.087LeuThr: 7.087 ± 1.016
5.222LeuVal: 5.222 ± 0.989
0.932LeuTrp: 0.932 ± 0.317
3.17LeuTyr: 3.17 ± 1.027
0.0LeuXaa: 0.0 ± 0.0
Met
1.492MetAla: 1.492 ± 0.427
0.373MetCys: 0.373 ± 0.159
1.865MetAsp: 1.865 ± 0.582
0.746MetGlu: 0.746 ± 0.286
0.186MetPhe: 0.186 ± 0.12
0.746MetGly: 0.746 ± 0.374
0.186MetHis: 0.186 ± 0.12
2.611MetIle: 2.611 ± 0.386
1.305MetLys: 1.305 ± 0.34
2.238MetLeu: 2.238 ± 0.629
1.492MetMet: 1.492 ± 0.526
1.305MetAsn: 1.305 ± 0.585
0.932MetPro: 0.932 ± 0.317
0.373MetGln: 0.373 ± 0.271
1.865MetArg: 1.865 ± 0.49
1.865MetSer: 1.865 ± 0.811
2.424MetThr: 2.424 ± 0.743
2.797MetVal: 2.797 ± 0.789
0.373MetTrp: 0.373 ± 0.228
1.492MetTyr: 1.492 ± 0.467
0.0MetXaa: 0.0 ± 0.0
Asn
1.305AsnAla: 1.305 ± 0.371
0.932AsnCys: 0.932 ± 0.381
2.051AsnAsp: 2.051 ± 0.628
2.797AsnGlu: 2.797 ± 0.617
1.678AsnPhe: 1.678 ± 0.377
3.17AsnGly: 3.17 ± 0.515
1.492AsnHis: 1.492 ± 0.455
5.968AsnIle: 5.968 ± 1.42
3.73AsnLys: 3.73 ± 1.211
7.646AsnLeu: 7.646 ± 1.743
0.932AsnMet: 0.932 ± 0.462
3.543AsnAsn: 3.543 ± 0.559
3.543AsnPro: 3.543 ± 0.722
2.051AsnGln: 2.051 ± 0.492
3.543AsnArg: 3.543 ± 0.697
3.73AsnSer: 3.73 ± 0.657
4.103AsnThr: 4.103 ± 0.721
2.051AsnVal: 2.051 ± 0.537
0.746AsnTrp: 0.746 ± 0.316
2.611AsnTyr: 2.611 ± 0.799
0.0AsnXaa: 0.0 ± 0.0
Pro
2.051ProAla: 2.051 ± 0.622
0.0ProCys: 0.0 ± 0.0
2.611ProAsp: 2.611 ± 0.853
2.424ProGlu: 2.424 ± 0.653
1.305ProPhe: 1.305 ± 0.418
2.797ProGly: 2.797 ± 0.953
0.373ProHis: 0.373 ± 0.239
3.916ProIle: 3.916 ± 0.59
4.103ProLys: 4.103 ± 1.06
2.984ProLeu: 2.984 ± 0.486
1.305ProMet: 1.305 ± 0.322
4.662ProAsn: 4.662 ± 0.996
1.492ProPro: 1.492 ± 0.487
1.305ProGln: 1.305 ± 0.56
2.424ProArg: 2.424 ± 0.698
3.543ProSer: 3.543 ± 0.625
2.984ProThr: 2.984 ± 1.325
2.238ProVal: 2.238 ± 0.721
0.186ProTrp: 0.186 ± 0.257
2.797ProTyr: 2.797 ± 0.519
0.0ProXaa: 0.0 ± 0.0
Gln
2.424GlnAla: 2.424 ± 0.588
0.932GlnCys: 0.932 ± 0.381
2.238GlnAsp: 2.238 ± 1.043
2.051GlnGlu: 2.051 ± 0.579
1.492GlnPhe: 1.492 ± 0.575
2.424GlnGly: 2.424 ± 0.676
1.119GlnHis: 1.119 ± 0.457
3.17GlnIle: 3.17 ± 0.539
2.611GlnLys: 2.611 ± 0.815
3.73GlnLeu: 3.73 ± 1.142
2.051GlnMet: 2.051 ± 0.474
1.119GlnAsn: 1.119 ± 0.316
1.492GlnPro: 1.492 ± 0.346
1.119GlnGln: 1.119 ± 0.379
2.797GlnArg: 2.797 ± 0.442
2.051GlnSer: 2.051 ± 0.395
2.611GlnThr: 2.611 ± 0.642
1.492GlnVal: 1.492 ± 0.426
0.186GlnTrp: 0.186 ± 0.175
1.119GlnTyr: 1.119 ± 0.344
0.0GlnXaa: 0.0 ± 0.0
Arg
3.17ArgAla: 3.17 ± 0.73
1.119ArgCys: 1.119 ± 0.425
3.17ArgAsp: 3.17 ± 0.753
4.103ArgGlu: 4.103 ± 1.765
1.119ArgPhe: 1.119 ± 0.4
3.357ArgGly: 3.357 ± 0.705
0.559ArgHis: 0.559 ± 0.22
2.797ArgIle: 2.797 ± 0.516
2.984ArgLys: 2.984 ± 0.39
4.476ArgLeu: 4.476 ± 1.519
1.492ArgMet: 1.492 ± 0.378
2.424ArgAsn: 2.424 ± 0.338
3.17ArgPro: 3.17 ± 0.644
2.051ArgGln: 2.051 ± 0.614
3.73ArgArg: 3.73 ± 1.075
4.849ArgSer: 4.849 ± 0.548
2.611ArgThr: 2.611 ± 1.307
3.357ArgVal: 3.357 ± 0.549
0.746ArgTrp: 0.746 ± 0.376
0.932ArgTyr: 0.932 ± 0.3
0.0ArgXaa: 0.0 ± 0.0
Ser
2.424SerAla: 2.424 ± 0.679
0.746SerCys: 0.746 ± 0.318
6.527SerAsp: 6.527 ± 1.224
4.476SerGlu: 4.476 ± 0.917
3.543SerPhe: 3.543 ± 0.529
4.103SerGly: 4.103 ± 1.316
1.678SerHis: 1.678 ± 0.323
6.714SerIle: 6.714 ± 0.789
4.289SerLys: 4.289 ± 0.518
8.579SerLeu: 8.579 ± 1.196
2.424SerMet: 2.424 ± 0.691
5.781SerAsn: 5.781 ± 0.756
2.051SerPro: 2.051 ± 0.409
3.357SerGln: 3.357 ± 0.628
5.408SerArg: 5.408 ± 1.027
5.968SerSer: 5.968 ± 1.466
5.035SerThr: 5.035 ± 0.771
4.662SerVal: 4.662 ± 0.577
0.932SerTrp: 0.932 ± 0.307
3.17SerTyr: 3.17 ± 0.922
0.0SerXaa: 0.0 ± 0.0
Thr
3.17ThrAla: 3.17 ± 1.295
0.0ThrCys: 0.0 ± 0.0
2.424ThrAsp: 2.424 ± 0.364
3.17ThrGlu: 3.17 ± 0.747
2.238ThrPhe: 2.238 ± 0.342
3.916ThrGly: 3.916 ± 0.344
0.559ThrHis: 0.559 ± 0.397
7.087ThrIle: 7.087 ± 1.361
3.17ThrLys: 3.17 ± 0.394
5.781ThrLeu: 5.781 ± 1.627
1.119ThrMet: 1.119 ± 0.314
4.103ThrAsn: 4.103 ± 0.499
3.73ThrPro: 3.73 ± 1.092
2.984ThrGln: 2.984 ± 1.236
2.611ThrArg: 2.611 ± 1.004
4.849ThrSer: 4.849 ± 1.483
5.781ThrThr: 5.781 ± 2.45
2.611ThrVal: 2.611 ± 0.692
0.373ThrTrp: 0.373 ± 0.239
2.611ThrTyr: 2.611 ± 0.863
0.0ThrXaa: 0.0 ± 0.0
Val
2.424ValAla: 2.424 ± 0.948
0.373ValCys: 0.373 ± 0.364
3.543ValAsp: 3.543 ± 1.222
2.984ValGlu: 2.984 ± 0.681
2.611ValPhe: 2.611 ± 0.433
3.543ValGly: 3.543 ± 0.32
1.119ValHis: 1.119 ± 0.419
4.103ValIle: 4.103 ± 1.175
4.103ValLys: 4.103 ± 1.091
5.595ValLeu: 5.595 ± 0.481
0.932ValMet: 0.932 ± 0.606
3.357ValAsn: 3.357 ± 0.808
3.916ValPro: 3.916 ± 0.478
0.746ValGln: 0.746 ± 0.404
1.492ValArg: 1.492 ± 0.446
5.595ValSer: 5.595 ± 1.519
4.103ValThr: 4.103 ± 1.15
3.73ValVal: 3.73 ± 0.428
0.0ValTrp: 0.0 ± 0.0
2.424ValTyr: 2.424 ± 0.962
0.0ValXaa: 0.0 ± 0.0
Trp
0.559TrpAla: 0.559 ± 0.359
0.186TrpCys: 0.186 ± 0.175
0.559TrpAsp: 0.559 ± 0.22
0.559TrpGlu: 0.559 ± 0.257
0.373TrpPhe: 0.373 ± 0.239
0.186TrpGly: 0.186 ± 0.224
0.373TrpHis: 0.373 ± 0.159
0.559TrpIle: 0.559 ± 0.22
1.119TrpLys: 1.119 ± 0.527
0.932TrpLeu: 0.932 ± 0.394
0.0TrpMet: 0.0 ± 0.0
0.373TrpAsn: 0.373 ± 0.228
0.186TrpPro: 0.186 ± 0.12
0.0TrpGln: 0.0 ± 0.0
0.373TrpArg: 0.373 ± 0.188
0.932TrpSer: 0.932 ± 0.415
0.559TrpThr: 0.559 ± 0.359
0.746TrpVal: 0.746 ± 0.513
0.186TrpTrp: 0.186 ± 0.12
0.746TrpTyr: 0.746 ± 0.318
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.424TyrAla: 2.424 ± 0.86
0.932TyrCys: 0.932 ± 0.213
1.865TyrAsp: 1.865 ± 0.666
0.746TyrGlu: 0.746 ± 0.346
2.424TyrPhe: 2.424 ± 0.554
2.984TyrGly: 2.984 ± 0.769
0.746TyrHis: 0.746 ± 0.271
2.238TyrIle: 2.238 ± 0.72
2.611TyrLys: 2.611 ± 0.708
5.595TyrLeu: 5.595 ± 1.285
0.932TyrMet: 0.932 ± 0.293
1.865TyrAsn: 1.865 ± 0.678
2.611TyrPro: 2.611 ± 0.775
2.238TyrGln: 2.238 ± 0.535
0.932TyrArg: 0.932 ± 0.271
2.797TyrSer: 2.797 ± 1.193
2.611TyrThr: 2.611 ± 0.773
1.305TyrVal: 1.305 ± 0.513
0.373TyrTrp: 0.373 ± 0.239
1.865TyrTyr: 1.865 ± 0.632
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (5363 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski