Amino acid dipepetide frequency for Striga asiatica (Asiatic witchweed) (Buchnera asiatica)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.267AlaAla: 7.267 ± 0.04	1.282AlaCys: 1.282 ± 0.012	3.327AlaAsp: 3.327 ± 0.015	4.275AlaGlu: 4.275 ± 0.022	2.708AlaPhe: 2.708 ± 0.017	4.552AlaGly: 4.552 ± 0.026	1.519AlaHis: 1.519 ± 0.012	3.52AlaIle: 3.52 ± 0.019	3.743AlaLys: 3.743 ± 0.019	6.466AlaLeu: 6.466 ± 0.028	1.656AlaMet: 1.656 ± 0.011	2.593AlaAsn: 2.593 ± 0.014	2.984AlaPro: 2.984 ± 0.019	2.151AlaGln: 2.151 ± 0.014	4.166AlaArg: 4.166 ± 0.02	5.826AlaSer: 5.826 ± 0.028	3.456AlaThr: 3.456 ± 0.017	5.126AlaVal: 5.126 ± 0.022	0.78AlaTrp: 0.78 ± 0.007	1.762AlaTyr: 1.762 ± 0.013	0.001AlaXaa: 0.001 ± 0.0
Cys	1.052CysAla: 1.052 ± 0.01	0.552CysCys: 0.552 ± 0.008	0.867CysAsp: 0.867 ± 0.008	0.937CysGlu: 0.937 ± 0.009	0.891CysPhe: 0.891 ± 0.009	1.521CysGly: 1.521 ± 0.014	0.471CysHis: 0.471 ± 0.007	0.902CysIle: 0.902 ± 0.008	1.044CysLys: 1.044 ± 0.011	1.916CysLeu: 1.916 ± 0.013	0.422CysMet: 0.422 ± 0.006	0.786CysAsn: 0.786 ± 0.008	0.999CysPro: 0.999 ± 0.01	0.555CysGln: 0.555 ± 0.007	1.295CysArg: 1.295 ± 0.011	1.846CysSer: 1.846 ± 0.014	0.905CysThr: 0.905 ± 0.009	1.159CysVal: 1.159 ± 0.01	0.288CysTrp: 0.288 ± 0.005	0.561CysTyr: 0.561 ± 0.008	0.001CysXaa: 0.001 ± 0.0
Asp	3.211AspAla: 3.211 ± 0.017	0.987AspCys: 0.987 ± 0.01	3.734AspAsp: 3.734 ± 0.029	4.28AspGlu: 4.28 ± 0.024	2.455AspPhe: 2.455 ± 0.015	3.943AspGly: 3.943 ± 0.021	1.163AspHis: 1.163 ± 0.009	2.792AspIle: 2.792 ± 0.017	2.626AspLys: 2.626 ± 0.015	5.085AspLeu: 5.085 ± 0.025	1.244AspMet: 1.244 ± 0.01	2.054AspAsn: 2.054 ± 0.015	2.682AspPro: 2.682 ± 0.017	1.534AspGln: 1.534 ± 0.013	2.622AspArg: 2.622 ± 0.016	4.121AspSer: 4.121 ± 0.02	2.025AspThr: 2.025 ± 0.013	3.609AspVal: 3.609 ± 0.021	0.72AspTrp: 0.72 ± 0.008	1.528AspTyr: 1.528 ± 0.013	0.002AspXaa: 0.002 ± 0.0
Glu	4.656GluAla: 4.656 ± 0.022	0.92GluCys: 0.92 ± 0.009	3.844GluAsp: 3.844 ± 0.019	5.767GluGlu: 5.767 ± 0.039	2.377GluPhe: 2.377 ± 0.014	3.781GluGly: 3.781 ± 0.02	1.264GluHis: 1.264 ± 0.01	3.791GluIle: 3.791 ± 0.021	4.897GluLys: 4.897 ± 0.027	5.782GluLeu: 5.782 ± 0.028	1.736GluMet: 1.736 ± 0.014	3.335GluAsn: 3.335 ± 0.021	2.325GluPro: 2.325 ± 0.016	2.041GluGln: 2.041 ± 0.014	3.637GluArg: 3.637 ± 0.024	4.583GluSer: 4.583 ± 0.022	2.901GluThr: 2.901 ± 0.017	4.1GluVal: 4.1 ± 0.023	0.728GluTrp: 0.728 ± 0.008	1.596GluTyr: 1.596 ± 0.011	0.001GluXaa: 0.001 ± 0.0
Phe	2.557PheAla: 2.557 ± 0.016	0.94PheCys: 0.94 ± 0.01	2.358PheAsp: 2.358 ± 0.017	2.365PheGlu: 2.365 ± 0.014	2.02PhePhe: 2.02 ± 0.016	3.11PheGly: 3.11 ± 0.02	1.099PheHis: 1.099 ± 0.01	1.926PheIle: 1.926 ± 0.014	1.923PheLys: 1.923 ± 0.012	4.295PheLeu: 4.295 ± 0.021	0.921PheMet: 0.921 ± 0.009	1.601PheAsn: 1.601 ± 0.011	2.162PhePro: 2.162 ± 0.015	1.442PheGln: 1.442 ± 0.012	2.326PheArg: 2.326 ± 0.016	4.162PheSer: 4.162 ± 0.021	2.013PheThr: 2.013 ± 0.013	2.889PheVal: 2.889 ± 0.018	0.572PheTrp: 0.572 ± 0.007	1.228PheTyr: 1.228 ± 0.012	0.003PheXaa: 0.003 ± 0.0
Gly	3.991GlyAla: 3.991 ± 0.022	1.338GlyCys: 1.338 ± 0.012	3.489GlyAsp: 3.489 ± 0.021	3.898GlyGlu: 3.898 ± 0.021	3.156GlyPhe: 3.156 ± 0.018	6.038GlyGly: 6.038 ± 0.044	1.613GlyHis: 1.613 ± 0.012	3.367GlyIle: 3.367 ± 0.021	4.149GlyLys: 4.149 ± 0.021	6.187GlyLeu: 6.187 ± 0.025	1.424GlyMet: 1.424 ± 0.012	2.903GlyAsn: 2.903 ± 0.023	3.35GlyPro: 3.35 ± 0.024	2.107GlyGln: 2.107 ± 0.017	4.266GlyArg: 4.266 ± 0.025	5.883GlySer: 5.883 ± 0.028	3.006GlyThr: 3.006 ± 0.016	4.306GlyVal: 4.306 ± 0.023	0.948GlyTrp: 0.948 ± 0.01	1.949GlyTyr: 1.949 ± 0.015	0.002GlyXaa: 0.002 ± 0.0
His	1.47HisAla: 1.47 ± 0.012	0.513HisCys: 0.513 ± 0.007	1.158HisAsp: 1.158 ± 0.01	1.37HisGlu: 1.37 ± 0.011	1.074HisPhe: 1.074 ± 0.01	1.704HisGly: 1.704 ± 0.012	1.001HisHis: 1.001 ± 0.012	1.213HisIle: 1.213 ± 0.01	1.208HisLys: 1.208 ± 0.01	2.459HisLeu: 2.459 ± 0.015	0.528HisMet: 0.528 ± 0.006	0.998HisAsn: 0.998 ± 0.01	1.417HisPro: 1.417 ± 0.012	0.984HisGln: 0.984 ± 0.011	1.577HisArg: 1.577 ± 0.012	1.88HisSer: 1.88 ± 0.014	1.043HisThr: 1.043 ± 0.01	1.624HisVal: 1.624 ± 0.012	0.319HisTrp: 0.319 ± 0.005	0.667HisTyr: 0.667 ± 0.008	0.001HisXaa: 0.001 ± 0.0
Ile	3.284IleAla: 3.284 ± 0.018	1.127IleCys: 1.127 ± 0.011	2.733IleAsp: 2.733 ± 0.016	3.065IleGlu: 3.065 ± 0.019	2.314IlePhe: 2.314 ± 0.017	3.312IleGly: 3.312 ± 0.017	1.298IleHis: 1.298 ± 0.01	2.659IleIle: 2.659 ± 0.02	2.713IleLys: 2.713 ± 0.017	5.096IleLeu: 5.096 ± 0.023	1.112IleMet: 1.112 ± 0.01	2.114IleAsn: 2.114 ± 0.012	2.908IlePro: 2.908 ± 0.018	1.775IleGln: 1.775 ± 0.012	2.806IleArg: 2.806 ± 0.016	4.781IleSer: 4.781 ± 0.022	2.51IleThr: 2.51 ± 0.014	3.344IleVal: 3.344 ± 0.021	0.697IleTrp: 0.697 ± 0.007	1.426IleTyr: 1.426 ± 0.013	0.003IleXaa: 0.003 ± 0.0
Lys	3.838LysAla: 3.838 ± 0.02	0.964LysCys: 0.964 ± 0.01	3.008LysAsp: 3.008 ± 0.017	4.216LysGlu: 4.216 ± 0.027	2.158LysPhe: 2.158 ± 0.015	3.457LysGly: 3.457 ± 0.017	1.277LysHis: 1.277 ± 0.011	3.275LysIle: 3.275 ± 0.017	4.795LysLys: 4.795 ± 0.037	5.626LysLeu: 5.626 ± 0.025	1.533LysMet: 1.533 ± 0.013	2.808LysAsn: 2.808 ± 0.016	2.771LysPro: 2.771 ± 0.017	2.072LysGln: 2.072 ± 0.014	3.721LysArg: 3.721 ± 0.021	4.777LysSer: 4.777 ± 0.024	2.895LysThr: 2.895 ± 0.015	3.589LysVal: 3.589 ± 0.017	0.799LysTrp: 0.799 ± 0.009	1.579LysTyr: 1.579 ± 0.012	0.003LysXaa: 0.003 ± 0.0
Leu	6.583LeuAla: 6.583 ± 0.025	1.883LeuCys: 1.883 ± 0.012	5.052LeuAsp: 5.052 ± 0.025	6.084LeuGlu: 6.084 ± 0.034	3.823LeuPhe: 3.823 ± 0.023	5.938LeuGly: 5.938 ± 0.026	2.599LeuHis: 2.599 ± 0.015	4.507LeuIle: 4.507 ± 0.024	5.782LeuLys: 5.782 ± 0.025	9.819LeuLeu: 9.819 ± 0.042	2.08LeuMet: 2.08 ± 0.013	3.826LeuAsn: 3.826 ± 0.019	5.214LeuPro: 5.214 ± 0.024	3.786LeuGln: 3.786 ± 0.02	5.842LeuArg: 5.842 ± 0.024	8.485LeuSer: 8.485 ± 0.037	4.471LeuThr: 4.471 ± 0.021	6.395LeuVal: 6.395 ± 0.029	1.198LeuTrp: 1.198 ± 0.011	2.402LeuTyr: 2.402 ± 0.014	0.003LeuXaa: 0.003 ± 0.0
Met	2.1MetAla: 2.1 ± 0.014	0.354MetCys: 0.354 ± 0.005	1.377MetAsp: 1.377 ± 0.011	1.81MetGlu: 1.81 ± 0.012	0.771MetPhe: 0.771 ± 0.008	1.579MetGly: 1.579 ± 0.011	0.5MetHis: 0.5 ± 0.007	1.088MetIle: 1.088 ± 0.012	1.548MetLys: 1.548 ± 0.012	2.029MetLeu: 2.029 ± 0.014	0.654MetMet: 0.654 ± 0.007	0.97MetAsn: 0.97 ± 0.008	1.029MetPro: 1.029 ± 0.009	0.819MetGln: 0.819 ± 0.009	1.311MetArg: 1.311 ± 0.011	1.769MetSer: 1.769 ± 0.013	1.009MetThr: 1.009 ± 0.009	1.575MetVal: 1.575 ± 0.012	0.292MetTrp: 0.292 ± 0.005	0.57MetTyr: 0.57 ± 0.008	0.001MetXaa: 0.001 ± 0.0
Asn	2.543AsnAla: 2.543 ± 0.015	0.848AsnCys: 0.848 ± 0.01	1.994AsnAsp: 1.994 ± 0.015	2.588AsnGlu: 2.588 ± 0.016	1.939AsnPhe: 1.939 ± 0.012	3.184AsnGly: 3.184 ± 0.017	1.065AsnHis: 1.065 ± 0.009	2.339AsnIle: 2.339 ± 0.015	2.32AsnLys: 2.32 ± 0.015	4.445AsnLeu: 4.445 ± 0.026	1.054AsnMet: 1.054 ± 0.009	2.53AsnAsn: 2.53 ± 0.027	2.54AsnPro: 2.54 ± 0.015	1.517AsnGln: 1.517 ± 0.011	2.314AsnArg: 2.314 ± 0.021	3.922AsnSer: 3.922 ± 0.023	1.927AsnThr: 1.927 ± 0.013	2.714AsnVal: 2.714 ± 0.016	0.585AsnTrp: 0.585 ± 0.007	1.263AsnTyr: 1.263 ± 0.012	0.002AsnXaa: 0.002 ± 0.0
Pro	3.517ProAla: 3.517 ± 0.022	0.825ProCys: 0.825 ± 0.01	2.63ProAsp: 2.63 ± 0.015	3.257ProGlu: 3.257 ± 0.015	2.145ProPhe: 2.145 ± 0.015	2.862ProGly: 2.862 ± 0.019	1.318ProHis: 1.318 ± 0.012	2.534ProIle: 2.534 ± 0.015	2.76ProLys: 2.76 ± 0.019	4.559ProLeu: 4.559 ± 0.018	0.987ProMet: 0.987 ± 0.01	2.54ProAsn: 2.54 ± 0.017	4.463ProPro: 4.463 ± 0.047	1.846ProGln: 1.846 ± 0.014	2.828ProArg: 2.828 ± 0.017	5.255ProSer: 5.255 ± 0.026	2.915ProThr: 2.915 ± 0.018	3.258ProVal: 3.258 ± 0.02	0.616ProTrp: 0.616 ± 0.008	1.284ProTyr: 1.284 ± 0.013	0.002ProXaa: 0.002 ± 0.0
Gln	2.257GlnAla: 2.257 ± 0.016	0.522GlnCys: 0.522 ± 0.007	1.453GlnAsp: 1.453 ± 0.012	2.156GlnGlu: 2.156 ± 0.015	1.298GlnPhe: 1.298 ± 0.01	1.869GlnGly: 1.869 ± 0.012	0.875GlnHis: 0.875 ± 0.009	1.997GlnIle: 1.997 ± 0.012	2.192GlnLys: 2.192 ± 0.015	3.394GlnLeu: 3.394 ± 0.017	0.928GlnMet: 0.928 ± 0.009	1.695GlnAsn: 1.695 ± 0.014	1.847GlnPro: 1.847 ± 0.015	1.775GlnGln: 1.775 ± 0.025	2.089GlnArg: 2.089 ± 0.013	2.702GlnSer: 2.702 ± 0.017	1.729GlnThr: 1.729 ± 0.012	2.15GlnVal: 2.15 ± 0.013	0.443GlnTrp: 0.443 ± 0.005	0.851GlnTyr: 0.851 ± 0.008	0.001GlnXaa: 0.001 ± 0.0
Arg	4.198ArgAla: 4.198 ± 0.021	1.07ArgCys: 1.07 ± 0.009	2.913ArgAsp: 2.913 ± 0.018	3.731ArgGlu: 3.731 ± 0.022	2.378ArgPhe: 2.378 ± 0.015	3.706ArgGly: 3.706 ± 0.024	1.526ArgHis: 1.526 ± 0.011	3.015ArgIle: 3.015 ± 0.017	4.082ArgLys: 4.082 ± 0.025	5.64ArgLeu: 5.64 ± 0.024	1.395ArgMet: 1.395 ± 0.011	2.508ArgAsn: 2.508 ± 0.014	3.029ArgPro: 3.029 ± 0.017	2.036ArgGln: 2.036 ± 0.014	5.218ArgArg: 5.218 ± 0.035	4.66ArgSer: 4.66 ± 0.027	2.718ArgThr: 2.718 ± 0.016	3.919ArgVal: 3.919 ± 0.021	0.915ArgTrp: 0.915 ± 0.01	1.459ArgTyr: 1.459 ± 0.011	0.003ArgXaa: 0.003 ± 0.0
Ser	5.581SerAla: 5.581 ± 0.022	1.776SerCys: 1.776 ± 0.014	4.243SerAsp: 4.243 ± 0.023	4.703SerGlu: 4.703 ± 0.021	3.847SerPhe: 3.847 ± 0.022	6.221SerGly: 6.221 ± 0.027	1.991SerHis: 1.991 ± 0.015	4.329SerIle: 4.329 ± 0.02	4.641SerLys: 4.641 ± 0.022	8.328SerLeu: 8.328 ± 0.035	1.895SerMet: 1.895 ± 0.014	3.789SerAsn: 3.789 ± 0.021	5.042SerPro: 5.042 ± 0.03	2.82SerGln: 2.82 ± 0.02	5.197SerArg: 5.197 ± 0.027	10.655SerSer: 10.655 ± 0.051	4.621SerThr: 4.621 ± 0.024	5.211SerVal: 5.211 ± 0.025	1.204SerTrp: 1.204 ± 0.01	2.215SerTyr: 2.215 ± 0.014	0.003SerXaa: 0.003 ± 0.001
Thr	3.481ThrAla: 3.481 ± 0.018	0.972ThrCys: 0.972 ± 0.011	2.199ThrAsp: 2.199 ± 0.014	2.622ThrGlu: 2.622 ± 0.018	2.023ThrPhe: 2.023 ± 0.012	3.224ThrGly: 3.224 ± 0.017	1.085ThrHis: 1.085 ± 0.009	2.587ThrIle: 2.587 ± 0.017	2.62ThrLys: 2.62 ± 0.016	4.532ThrLeu: 4.532 ± 0.022	1.049ThrMet: 1.049 ± 0.009	2.105ThrAsn: 2.105 ± 0.015	2.61ThrPro: 2.61 ± 0.017	1.5ThrGln: 1.5 ± 0.013	2.739ThrArg: 2.739 ± 0.015	4.476ThrSer: 4.476 ± 0.02	2.862ThrThr: 2.862 ± 0.018	3.268ThrVal: 3.268 ± 0.018	0.662ThrTrp: 0.662 ± 0.008	1.316ThrTyr: 1.316 ± 0.012	0.001ThrXaa: 0.001 ± 0.0
Val	4.924ValAla: 4.924 ± 0.022	1.238ValCys: 1.238 ± 0.01	3.865ValAsp: 3.865 ± 0.018	4.614ValGlu: 4.614 ± 0.023	2.732ValPhe: 2.732 ± 0.017	4.567ValGly: 4.567 ± 0.023	1.588ValHis: 1.588 ± 0.012	3.199ValIle: 3.199 ± 0.019	3.814ValLys: 3.814 ± 0.019	6.217ValLeu: 6.217 ± 0.024	1.545ValMet: 1.545 ± 0.012	2.569ValAsn: 2.569 ± 0.015	3.22ValPro: 3.22 ± 0.018	2.183ValGln: 2.183 ± 0.014	3.654ValArg: 3.654 ± 0.02	5.241ValSer: 5.241 ± 0.023	3.025ValThr: 3.025 ± 0.015	5.211ValVal: 5.211 ± 0.026	0.82ValTrp: 0.82 ± 0.009	1.831ValTyr: 1.831 ± 0.013	0.002ValXaa: 0.002 ± 0.0
Trp	0.951TrpAla: 0.951 ± 0.01	0.252TrpCys: 0.252 ± 0.004	0.728TrpAsp: 0.728 ± 0.008	0.75TrpGlu: 0.75 ± 0.008	0.528TrpPhe: 0.528 ± 0.007	0.793TrpGly: 0.793 ± 0.009	0.297TrpHis: 0.297 ± 0.005	0.681TrpIle: 0.681 ± 0.008	0.891TrpLys: 0.891 ± 0.008	1.239TrpLeu: 1.239 ± 0.011	0.337TrpMet: 0.337 ± 0.005	0.657TrpAsn: 0.657 ± 0.009	0.574TrpPro: 0.574 ± 0.007	0.429TrpGln: 0.429 ± 0.006	0.997TrpArg: 0.997 ± 0.01	1.024TrpSer: 1.024 ± 0.01	0.662TrpThr: 0.662 ± 0.007	0.857TrpVal: 0.857 ± 0.009	0.276TrpTrp: 0.276 ± 0.005	0.325TrpTyr: 0.325 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.698TyrAla: 1.698 ± 0.014	0.605TyrCys: 0.605 ± 0.008	1.443TyrAsp: 1.443 ± 0.011	1.572TyrGlu: 1.572 ± 0.013	1.273TyrPhe: 1.273 ± 0.01	2.009TyrGly: 2.009 ± 0.015	0.66TyrHis: 0.66 ± 0.008	1.353TyrIle: 1.353 ± 0.011	1.41TyrLys: 1.41 ± 0.012	2.654TyrLeu: 2.654 ± 0.018	0.654TyrMet: 0.654 ± 0.007	1.251TyrAsn: 1.251 ± 0.012	1.232TyrPro: 1.232 ± 0.012	0.849TyrGln: 0.849 ± 0.009	1.516TyrArg: 1.516 ± 0.012	2.261TyrSer: 2.261 ± 0.016	1.238TyrThr: 1.238 ± 0.011	1.752TyrVal: 1.752 ± 0.014	0.385TyrTrp: 0.385 ± 0.006	0.941TyrTyr: 0.941 ± 0.011	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.003XaaPhe: 0.003 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.002XaaIle: 0.002 ± 0.0	0.002XaaLys: 0.002 ± 0.0	0.003XaaLeu: 0.003 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.002XaaAsn: 0.002 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.003XaaSer: 0.003 ± 0.0	0.002XaaThr: 0.002 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.015XaaXaa: 0.015 ± 0.004

Statistics based on 33322 proteins (12314773 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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