Amino acid dipepetide frequency for Bovine rotavirus C

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.473AlaAla: 4.473 ± 0.466
1.789AlaCys: 1.789 ± 0.89
3.042AlaAsp: 3.042 ± 0.694
3.221AlaGlu: 3.221 ± 0.927
2.684AlaPhe: 2.684 ± 0.766
2.863AlaGly: 2.863 ± 0.667
1.252AlaHis: 1.252 ± 0.437
5.547AlaIle: 5.547 ± 0.869
3.936AlaLys: 3.936 ± 1.059
5.189AlaLeu: 5.189 ± 1.078
2.684AlaMet: 2.684 ± 0.567
3.221AlaAsn: 3.221 ± 0.477
1.431AlaPro: 1.431 ± 0.443
2.684AlaGln: 2.684 ± 0.632
2.147AlaArg: 2.147 ± 0.654
5.547AlaSer: 5.547 ± 1.129
3.221AlaThr: 3.221 ± 0.605
3.936AlaVal: 3.936 ± 0.49
0.358AlaTrp: 0.358 ± 0.217
2.147AlaTyr: 2.147 ± 0.336
0.0AlaXaa: 0.0 ± 0.0
Cys
0.358CysAla: 0.358 ± 0.267
0.0CysCys: 0.0 ± 0.0
1.252CysAsp: 1.252 ± 0.688
0.358CysGlu: 0.358 ± 0.214
0.716CysPhe: 0.716 ± 0.302
0.358CysGly: 0.358 ± 0.267
0.537CysHis: 0.537 ± 0.4
1.431CysIle: 1.431 ± 0.674
0.537CysLys: 0.537 ± 0.281
0.895CysLeu: 0.895 ± 0.344
0.716CysMet: 0.716 ± 0.256
0.537CysAsn: 0.537 ± 0.303
0.537CysPro: 0.537 ± 0.327
0.895CysGln: 0.895 ± 0.48
0.537CysArg: 0.537 ± 0.3
0.895CysSer: 0.895 ± 0.436
0.895CysThr: 0.895 ± 0.468
1.252CysVal: 1.252 ± 0.542
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.505AspAla: 2.505 ± 0.638
0.716AspCys: 0.716 ± 0.421
4.294AspAsp: 4.294 ± 1.025
4.831AspGlu: 4.831 ± 1.143
3.221AspPhe: 3.221 ± 0.913
3.757AspGly: 3.757 ± 0.514
0.537AspHis: 0.537 ± 0.204
3.936AspIle: 3.936 ± 0.809
1.789AspLys: 1.789 ± 0.779
4.294AspLeu: 4.294 ± 1.013
2.505AspMet: 2.505 ± 0.461
3.936AspAsn: 3.936 ± 0.927
1.252AspPro: 1.252 ± 0.469
1.61AspGln: 1.61 ± 0.286
1.968AspArg: 1.968 ± 0.644
3.578AspSer: 3.578 ± 1.013
4.115AspThr: 4.115 ± 0.783
5.904AspVal: 5.904 ± 0.758
0.537AspTrp: 0.537 ± 0.378
4.473AspTyr: 4.473 ± 0.497
0.0AspXaa: 0.0 ± 0.0
Glu
3.221GluAla: 3.221 ± 0.88
0.716GluCys: 0.716 ± 0.456
3.042GluAsp: 3.042 ± 0.557
3.578GluGlu: 3.578 ± 0.883
2.147GluPhe: 2.147 ± 0.542
2.505GluGly: 2.505 ± 0.564
0.537GluHis: 0.537 ± 0.253
5.547GluIle: 5.547 ± 0.983
5.01GluLys: 5.01 ± 1.015
4.652GluLeu: 4.652 ± 1.109
2.863GluMet: 2.863 ± 0.851
4.294GluAsn: 4.294 ± 1.157
0.179GluPro: 0.179 ± 0.177
1.074GluGln: 1.074 ± 0.385
3.4GluArg: 3.4 ± 0.542
5.189GluSer: 5.189 ± 1.206
1.968GluThr: 1.968 ± 0.873
2.863GluVal: 2.863 ± 0.876
1.431GluTrp: 1.431 ± 0.61
2.684GluTyr: 2.684 ± 0.704
0.0GluXaa: 0.0 ± 0.0
Phe
3.042PheAla: 3.042 ± 0.481
0.0PheCys: 0.0 ± 0.0
4.294PheAsp: 4.294 ± 0.766
1.968PheGlu: 1.968 ± 0.489
1.252PhePhe: 1.252 ± 0.411
1.61PheGly: 1.61 ± 0.534
0.716PheHis: 0.716 ± 0.36
3.936PheIle: 3.936 ± 0.778
4.652PheLys: 4.652 ± 0.631
2.505PheLeu: 2.505 ± 1.047
1.252PheMet: 1.252 ± 0.261
3.757PheAsn: 3.757 ± 0.795
1.789PhePro: 1.789 ± 0.592
0.895PheGln: 0.895 ± 0.384
2.147PheArg: 2.147 ± 0.37
3.936PheSer: 3.936 ± 0.615
2.684PheThr: 2.684 ± 0.596
2.326PheVal: 2.326 ± 0.466
0.537PheTrp: 0.537 ± 0.288
1.074PheTyr: 1.074 ± 0.33
0.0PheXaa: 0.0 ± 0.0
Gly
1.252GlyAla: 1.252 ± 0.308
0.537GlyCys: 0.537 ± 0.26
2.147GlyAsp: 2.147 ± 0.285
1.789GlyGlu: 1.789 ± 0.48
0.895GlyPhe: 0.895 ± 0.365
2.147GlyGly: 2.147 ± 0.828
0.358GlyHis: 0.358 ± 0.212
3.221GlyIle: 3.221 ± 0.798
3.578GlyLys: 3.578 ± 1.031
3.221GlyLeu: 3.221 ± 0.469
2.147GlyMet: 2.147 ± 0.602
2.684GlyAsn: 2.684 ± 0.733
0.895GlyPro: 0.895 ± 0.404
1.431GlyGln: 1.431 ± 0.389
1.968GlyArg: 1.968 ± 0.406
2.684GlySer: 2.684 ± 0.947
3.042GlyThr: 3.042 ± 0.948
2.863GlyVal: 2.863 ± 0.505
1.252GlyTrp: 1.252 ± 0.527
1.61GlyTyr: 1.61 ± 0.751
0.0GlyXaa: 0.0 ± 0.0
His
1.431HisAla: 1.431 ± 0.464
0.358HisCys: 0.358 ± 0.209
1.252HisAsp: 1.252 ± 0.413
1.252HisGlu: 1.252 ± 0.497
0.537HisPhe: 0.537 ± 0.322
0.716HisGly: 0.716 ± 0.396
0.716HisHis: 0.716 ± 0.295
1.074HisIle: 1.074 ± 0.401
1.074HisLys: 1.074 ± 0.326
1.61HisLeu: 1.61 ± 0.505
0.0HisMet: 0.0 ± 0.0
1.074HisAsn: 1.074 ± 0.591
0.537HisPro: 0.537 ± 0.303
0.358HisGln: 0.358 ± 0.249
0.537HisArg: 0.537 ± 0.412
1.431HisSer: 1.431 ± 0.288
1.074HisThr: 1.074 ± 0.349
1.789HisVal: 1.789 ± 0.525
0.358HisTrp: 0.358 ± 0.279
0.895HisTyr: 0.895 ± 0.278
0.0HisXaa: 0.0 ± 0.0
Ile
5.547IleAla: 5.547 ± 1.062
0.895IleCys: 0.895 ± 0.38
5.189IleAsp: 5.189 ± 0.72
4.294IleGlu: 4.294 ± 0.488
2.863IlePhe: 2.863 ± 0.606
3.221IleGly: 3.221 ± 0.801
1.968IleHis: 1.968 ± 0.784
4.652IleIle: 4.652 ± 0.765
4.473IleLys: 4.473 ± 0.665
5.189IleLeu: 5.189 ± 1.051
2.505IleMet: 2.505 ± 0.508
6.799IleAsn: 6.799 ± 1.149
4.294IlePro: 4.294 ± 1.089
2.326IleGln: 2.326 ± 0.59
3.221IleArg: 3.221 ± 0.558
5.189IleSer: 5.189 ± 0.672
5.904IleThr: 5.904 ± 0.825
4.831IleVal: 4.831 ± 0.791
0.358IleTrp: 0.358 ± 0.212
2.684IleTyr: 2.684 ± 0.875
0.0IleXaa: 0.0 ± 0.0
Lys
3.221LysAla: 3.221 ± 1.18
0.358LysCys: 0.358 ± 0.257
3.4LysAsp: 3.4 ± 0.423
3.578LysGlu: 3.578 ± 0.559
2.863LysPhe: 2.863 ± 0.696
1.789LysGly: 1.789 ± 0.576
2.147LysHis: 2.147 ± 0.591
6.978LysIle: 6.978 ± 1.028
4.294LysLys: 4.294 ± 0.862
6.262LysLeu: 6.262 ± 1.129
2.505LysMet: 2.505 ± 0.777
4.652LysAsn: 4.652 ± 0.743
1.252LysPro: 1.252 ± 0.272
1.789LysGln: 1.789 ± 0.546
3.578LysArg: 3.578 ± 0.768
5.01LysSer: 5.01 ± 1.303
4.473LysThr: 4.473 ± 0.916
4.115LysVal: 4.115 ± 0.769
1.252LysTrp: 1.252 ± 0.529
3.042LysTyr: 3.042 ± 0.814
0.0LysXaa: 0.0 ± 0.0
Leu
6.262LeuAla: 6.262 ± 0.622
1.074LeuCys: 1.074 ± 0.52
3.936LeuAsp: 3.936 ± 0.846
3.936LeuGlu: 3.936 ± 0.658
4.473LeuPhe: 4.473 ± 0.82
1.968LeuGly: 1.968 ± 0.411
1.431LeuHis: 1.431 ± 0.412
5.189LeuIle: 5.189 ± 0.773
5.368LeuLys: 5.368 ± 1.223
6.083LeuLeu: 6.083 ± 0.832
2.147LeuMet: 2.147 ± 0.503
6.62LeuAsn: 6.62 ± 1.195
2.863LeuPro: 2.863 ± 0.452
2.505LeuGln: 2.505 ± 0.87
5.189LeuArg: 5.189 ± 1.188
7.336LeuSer: 7.336 ± 0.949
4.831LeuThr: 4.831 ± 1.263
4.831LeuVal: 4.831 ± 1.248
0.716LeuTrp: 0.716 ± 0.365
3.4LeuTyr: 3.4 ± 0.886
0.0LeuXaa: 0.0 ± 0.0
Met
2.863MetAla: 2.863 ± 0.637
0.179MetCys: 0.179 ± 0.172
2.147MetAsp: 2.147 ± 0.78
1.252MetGlu: 1.252 ± 0.44
1.074MetPhe: 1.074 ± 0.428
0.895MetGly: 0.895 ± 0.52
0.537MetHis: 0.537 ± 0.355
1.789MetIle: 1.789 ± 0.538
2.326MetLys: 2.326 ± 0.342
3.221MetLeu: 3.221 ± 0.942
0.895MetMet: 0.895 ± 0.532
2.326MetAsn: 2.326 ± 0.41
1.431MetPro: 1.431 ± 0.621
1.252MetGln: 1.252 ± 0.64
2.147MetArg: 2.147 ± 1.057
2.505MetSer: 2.505 ± 0.609
2.505MetThr: 2.505 ± 0.387
2.863MetVal: 2.863 ± 0.976
0.179MetTrp: 0.179 ± 0.16
2.147MetTyr: 2.147 ± 0.481
0.0MetXaa: 0.0 ± 0.0
Asn
4.115AsnAla: 4.115 ± 0.782
0.716AsnCys: 0.716 ± 0.39
3.042AsnAsp: 3.042 ± 0.913
5.368AsnGlu: 5.368 ± 0.882
2.684AsnPhe: 2.684 ± 0.986
4.473AsnGly: 4.473 ± 0.785
1.074AsnHis: 1.074 ± 0.441
3.4AsnIle: 3.4 ± 0.629
4.473AsnLys: 4.473 ± 0.717
4.115AsnLeu: 4.115 ± 0.788
2.147AsnMet: 2.147 ± 0.413
4.473AsnAsn: 4.473 ± 0.844
2.505AsnPro: 2.505 ± 0.917
1.61AsnGln: 1.61 ± 0.441
2.863AsnArg: 2.863 ± 1.088
6.083AsnSer: 6.083 ± 1.411
4.473AsnThr: 4.473 ± 0.951
6.441AsnVal: 6.441 ± 1.106
0.537AsnTrp: 0.537 ± 0.312
4.831AsnTyr: 4.831 ± 0.394
0.0AsnXaa: 0.0 ± 0.0
Pro
1.968ProAla: 1.968 ± 0.588
0.0ProCys: 0.0 ± 0.0
1.789ProAsp: 1.789 ± 0.6
1.252ProGlu: 1.252 ± 0.585
0.537ProPhe: 0.537 ± 0.361
1.61ProGly: 1.61 ± 0.451
0.0ProHis: 0.0 ± 0.0
3.042ProIle: 3.042 ± 0.611
1.074ProLys: 1.074 ± 0.274
2.684ProLeu: 2.684 ± 0.508
1.074ProMet: 1.074 ± 0.629
1.789ProAsn: 1.789 ± 0.5
1.252ProPro: 1.252 ± 0.407
1.252ProGln: 1.252 ± 0.868
1.252ProArg: 1.252 ± 0.435
1.431ProSer: 1.431 ± 0.556
2.505ProThr: 2.505 ± 0.67
1.968ProVal: 1.968 ± 0.686
0.358ProTrp: 0.358 ± 0.283
2.326ProTyr: 2.326 ± 0.524
0.0ProXaa: 0.0 ± 0.0
Gln
2.147GlnAla: 2.147 ± 0.618
0.358GlnCys: 0.358 ± 0.294
0.716GlnAsp: 0.716 ± 0.34
0.895GlnGlu: 0.895 ± 0.391
2.326GlnPhe: 2.326 ± 0.524
0.358GlnGly: 0.358 ± 0.258
0.895GlnHis: 0.895 ± 0.498
1.61GlnIle: 1.61 ± 0.632
1.789GlnLys: 1.789 ± 0.51
5.189GlnLeu: 5.189 ± 0.65
1.252GlnMet: 1.252 ± 0.506
0.895GlnAsn: 0.895 ± 0.309
1.431GlnPro: 1.431 ± 0.677
1.61GlnGln: 1.61 ± 0.71
0.895GlnArg: 0.895 ± 0.229
2.505GlnSer: 2.505 ± 1.03
2.326GlnThr: 2.326 ± 0.587
2.505GlnVal: 2.505 ± 0.707
0.358GlnTrp: 0.358 ± 0.209
1.789GlnTyr: 1.789 ± 0.516
0.0GlnXaa: 0.0 ± 0.0
Arg
2.505ArgAla: 2.505 ± 0.444
0.537ArgCys: 0.537 ± 0.356
2.326ArgAsp: 2.326 ± 0.414
2.326ArgGlu: 2.326 ± 0.778
2.863ArgPhe: 2.863 ± 0.476
1.252ArgGly: 1.252 ± 0.451
0.895ArgHis: 0.895 ± 0.394
3.936ArgIle: 3.936 ± 0.867
3.221ArgLys: 3.221 ± 0.722
4.652ArgLeu: 4.652 ± 0.764
1.252ArgMet: 1.252 ± 0.409
3.757ArgAsn: 3.757 ± 0.623
0.895ArgPro: 0.895 ± 0.462
1.789ArgGln: 1.789 ± 0.483
3.4ArgArg: 3.4 ± 0.661
4.294ArgSer: 4.294 ± 0.638
2.147ArgThr: 2.147 ± 0.619
1.968ArgVal: 1.968 ± 0.821
0.895ArgTrp: 0.895 ± 0.485
2.505ArgTyr: 2.505 ± 0.732
0.0ArgXaa: 0.0 ± 0.0
Ser
6.083SerAla: 6.083 ± 0.796
1.252SerCys: 1.252 ± 0.4
4.473SerAsp: 4.473 ± 1.387
5.904SerGlu: 5.904 ± 0.938
3.757SerPhe: 3.757 ± 0.719
2.863SerGly: 2.863 ± 1.075
1.431SerHis: 1.431 ± 0.622
6.441SerIle: 6.441 ± 1.348
4.831SerLys: 4.831 ± 1.009
4.831SerLeu: 4.831 ± 1.125
1.968SerMet: 1.968 ± 0.395
6.441SerAsn: 6.441 ± 0.717
1.61SerPro: 1.61 ± 0.77
3.221SerGln: 3.221 ± 0.726
2.684SerArg: 2.684 ± 0.534
5.904SerSer: 5.904 ± 1.012
4.115SerThr: 4.115 ± 1.01
5.368SerVal: 5.368 ± 1.224
0.537SerTrp: 0.537 ± 0.328
4.115SerTyr: 4.115 ± 0.64
0.0SerXaa: 0.0 ± 0.0
Thr
3.578ThrAla: 3.578 ± 0.46
0.895ThrCys: 0.895 ± 0.477
3.4ThrAsp: 3.4 ± 0.659
3.578ThrGlu: 3.578 ± 0.688
2.505ThrPhe: 2.505 ± 0.751
1.968ThrGly: 1.968 ± 0.545
0.895ThrHis: 0.895 ± 0.437
5.368ThrIle: 5.368 ± 0.855
4.294ThrLys: 4.294 ± 0.705
4.473ThrLeu: 4.473 ± 0.99
2.326ThrMet: 2.326 ± 0.583
4.473ThrAsn: 4.473 ± 0.949
2.147ThrPro: 2.147 ± 0.483
1.61ThrGln: 1.61 ± 0.684
2.326ThrArg: 2.326 ± 0.483
4.294ThrSer: 4.294 ± 0.811
5.368ThrThr: 5.368 ± 1.271
4.652ThrVal: 4.652 ± 0.87
0.358ThrTrp: 0.358 ± 0.264
5.189ThrTyr: 5.189 ± 1.254
0.0ThrXaa: 0.0 ± 0.0
Val
4.294ValAla: 4.294 ± 1.004
1.968ValCys: 1.968 ± 0.928
5.547ValAsp: 5.547 ± 0.953
4.831ValGlu: 4.831 ± 1.098
2.863ValPhe: 2.863 ± 0.45
2.863ValGly: 2.863 ± 0.641
1.431ValHis: 1.431 ± 0.385
4.473ValIle: 4.473 ± 0.849
5.547ValLys: 5.547 ± 0.768
6.441ValLeu: 6.441 ± 0.744
2.505ValMet: 2.505 ± 0.754
4.115ValAsn: 4.115 ± 0.745
1.789ValPro: 1.789 ± 0.424
1.968ValGln: 1.968 ± 0.843
3.757ValArg: 3.757 ± 0.694
4.652ValSer: 4.652 ± 0.856
3.042ValThr: 3.042 ± 0.514
4.115ValVal: 4.115 ± 0.714
0.358ValTrp: 0.358 ± 0.234
2.326ValTyr: 2.326 ± 0.48
0.0ValXaa: 0.0 ± 0.0
Trp
0.179TrpAla: 0.179 ± 0.192
0.179TrpCys: 0.179 ± 0.172
0.716TrpAsp: 0.716 ± 0.179
0.358TrpGlu: 0.358 ± 0.263
0.895TrpPhe: 0.895 ± 0.384
0.537TrpGly: 0.537 ± 0.331
0.179TrpHis: 0.179 ± 0.172
1.074TrpIle: 1.074 ± 0.318
1.431TrpLys: 1.431 ± 0.459
1.252TrpLeu: 1.252 ± 0.535
0.358TrpMet: 0.358 ± 0.273
0.895TrpAsn: 0.895 ± 0.482
0.0TrpPro: 0.0 ± 0.0
0.537TrpGln: 0.537 ± 0.204
0.716TrpArg: 0.716 ± 0.312
0.358TrpSer: 0.358 ± 0.264
0.537TrpThr: 0.537 ± 0.266
0.358TrpVal: 0.358 ± 0.268
0.358TrpTrp: 0.358 ± 0.24
0.358TrpTyr: 0.358 ± 0.205
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.326TyrAla: 2.326 ± 0.724
0.179TyrCys: 0.179 ± 0.16
3.757TyrAsp: 3.757 ± 0.926
2.326TyrGlu: 2.326 ± 0.746
3.221TyrPhe: 3.221 ± 0.618
1.968TyrGly: 1.968 ± 0.877
0.537TyrHis: 0.537 ± 0.252
3.757TyrIle: 3.757 ± 0.57
2.863TyrLys: 2.863 ± 0.387
3.4TyrLeu: 3.4 ± 0.657
1.431TyrMet: 1.431 ± 0.262
2.684TyrAsn: 2.684 ± 0.704
1.074TyrPro: 1.074 ± 0.492
1.431TyrGln: 1.431 ± 0.421
2.684TyrArg: 2.684 ± 0.548
5.01TyrSer: 5.01 ± 1.047
4.473TyrThr: 4.473 ± 0.86
3.936TyrVal: 3.936 ± 0.703
0.537TyrTrp: 0.537 ± 0.231
2.326TyrTyr: 2.326 ± 0.578
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (5590 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski