Cutibacterium acnes JCM 18920
Average proteome isoelectric point is 6.59
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 3343 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|W4UJT4|W4UJT4_CUTAC Fumarate hydratase class II OS=Cutibacterium acnes JCM 18920 OX=1302244 GN=JCM18920_2581 PE=4 SV=1
MM1 pKa = 7.78 VDD3 pKa = 3.39 EE4 pKa = 5.2 GSVATVGDD12 pKa = 4.22 RR13 pKa = 11.84 DD14 pKa = 3.63 PAIDD18 pKa = 4.0 GDD20 pKa = 3.92 AGLIEE25 pKa = 4.65 LLAPLEE31 pKa = 4.2 YY32 pKa = 10.97 AHH34 pKa = 7.06 DD35 pKa = 4.24 LSVYY39 pKa = 10.33 ACLGPDD45 pKa = 3.51 VNGGASGHH53 pKa = 6.13 SGLYY57 pKa = 9.81
Molecular weight: 5.75 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 3.813
IPC2_protein 3.757
IPC_protein 3.656
Toseland 3.465
ProMoST 3.884
Dawson 3.681
Bjellqvist 3.846
Wikipedia 3.681
Rodwell 3.503
Grimsley 3.389
Solomon 3.643
Lehninger 3.605
Nozaki 3.834
DTASelect 4.05
Thurlkill 3.554
EMBOSS 3.681
Sillero 3.795
Patrickios 0.299
IPC_peptide 3.643
IPC2_peptide 3.757
IPC2.peptide.svr19 3.742
Protein with the highest isoelectric point:
>tr|W4UJR7|W4UJR7_CUTAC 30S ribosomal protein S17 OS=Cutibacterium acnes JCM 18920 OX=1302244 GN=rpsQ PE=3 SV=1
MM1 pKa = 7.45 KK2 pKa = 9.61 RR3 pKa = 11.84 TFQPSNRR10 pKa = 11.84 RR11 pKa = 11.84 RR12 pKa = 11.84 ARR14 pKa = 11.84 NHH16 pKa = 5.31 GFRR19 pKa = 11.84 SRR21 pKa = 11.84 MSTRR25 pKa = 11.84 AGRR28 pKa = 11.84 SILAARR34 pKa = 11.84 RR35 pKa = 11.84 RR36 pKa = 11.84 KK37 pKa = 10.31 GRR39 pKa = 11.84 VNLSAA44 pKa = 4.92
Molecular weight: 5.17 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 9.527
IPC2_protein 11.316
IPC_protein 12.925
Toseland 13.086
ProMoST 13.583
Dawson 13.086
Bjellqvist 13.086
Wikipedia 13.554
Rodwell 12.647
Grimsley 13.115
Solomon 13.583
Lehninger 13.481
Nozaki 13.086
DTASelect 13.086
Thurlkill 13.086
EMBOSS 13.583
Sillero 13.086
Patrickios 12.369
IPC_peptide 13.583
IPC2_peptide 12.574
IPC2.peptide.svr19 9.248
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
3343
0
3343
694728
37
1086
207.8
22.52
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
10.83 ± 0.057
1.231 ± 0.015
6.034 ± 0.04
5.051 ± 0.045
2.862 ± 0.034
8.385 ± 0.042
2.504 ± 0.022
4.851 ± 0.033
2.838 ± 0.037
9.241 ± 0.047
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.62 ± 0.022
2.492 ± 0.025
5.535 ± 0.032
2.977 ± 0.022
7.142 ± 0.047
6.626 ± 0.044
6.417 ± 0.04
8.745 ± 0.045
1.701 ± 0.023
1.918 ± 0.026
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here