Amino acid dipepetide frequency for Mobilisporobacter senegalensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.063AlaAla: 5.063 ± 0.087	0.749AlaCys: 0.749 ± 0.025	3.369AlaAsp: 3.369 ± 0.057	3.696AlaGlu: 3.696 ± 0.069	2.582AlaPhe: 2.582 ± 0.055	4.811AlaGly: 4.811 ± 0.089	0.923AlaHis: 0.923 ± 0.031	5.729AlaIle: 5.729 ± 0.071	4.812AlaLys: 4.812 ± 0.068	5.707AlaLeu: 5.707 ± 0.077	1.863AlaMet: 1.863 ± 0.044	2.823AlaAsn: 2.823 ± 0.053	1.556AlaPro: 1.556 ± 0.042	1.56AlaGln: 1.56 ± 0.04	2.237AlaArg: 2.237 ± 0.039	3.695AlaSer: 3.695 ± 0.066	3.31AlaThr: 3.31 ± 0.067	4.402AlaVal: 4.402 ± 0.084	0.419AlaTrp: 0.419 ± 0.019	2.369AlaTyr: 2.369 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.629CysAla: 0.629 ± 0.022	0.165CysCys: 0.165 ± 0.013	0.621CysAsp: 0.621 ± 0.025	0.654CysGlu: 0.654 ± 0.027	0.551CysPhe: 0.551 ± 0.022	1.079CysGly: 1.079 ± 0.037	0.22CysHis: 0.22 ± 0.015	1.056CysIle: 1.056 ± 0.035	0.748CysLys: 0.748 ± 0.027	0.891CysLeu: 0.891 ± 0.028	0.327CysMet: 0.327 ± 0.019	0.615CysAsn: 0.615 ± 0.025	0.471CysPro: 0.471 ± 0.031	0.264CysGln: 0.264 ± 0.018	0.403CysArg: 0.403 ± 0.023	0.704CysSer: 0.704 ± 0.024	0.581CysThr: 0.581 ± 0.025	0.658CysVal: 0.658 ± 0.024	0.086CysTrp: 0.086 ± 0.009	0.452CysTyr: 0.452 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	3.073AspAla: 3.073 ± 0.058	0.618AspCys: 0.618 ± 0.026	2.806AspAsp: 2.806 ± 0.063	4.486AspGlu: 4.486 ± 0.072	2.628AspPhe: 2.628 ± 0.052	3.781AspGly: 3.781 ± 0.068	0.82AspHis: 0.82 ± 0.026	6.016AspIle: 6.016 ± 0.074	4.41AspLys: 4.41 ± 0.062	4.674AspLeu: 4.674 ± 0.065	1.696AspMet: 1.696 ± 0.038	3.129AspAsn: 3.129 ± 0.065	1.601AspPro: 1.601 ± 0.037	1.337AspGln: 1.337 ± 0.037	1.888AspArg: 1.888 ± 0.042	3.343AspSer: 3.343 ± 0.056	3.219AspThr: 3.219 ± 0.055	3.378AspVal: 3.378 ± 0.054	0.52AspTrp: 0.52 ± 0.022	2.914AspTyr: 2.914 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	4.53GluAla: 4.53 ± 0.064	0.663GluCys: 0.663 ± 0.025	4.284GluAsp: 4.284 ± 0.07	7.207GluGlu: 7.207 ± 0.092	2.948GluPhe: 2.948 ± 0.05	4.014GluGly: 4.014 ± 0.069	1.163GluHis: 1.163 ± 0.031	6.861GluIle: 6.861 ± 0.09	6.446GluLys: 6.446 ± 0.082	7.02GluLeu: 7.02 ± 0.091	2.038GluMet: 2.038 ± 0.044	4.509GluAsn: 4.509 ± 0.068	1.73GluPro: 1.73 ± 0.044	2.504GluGln: 2.504 ± 0.049	2.678GluArg: 2.678 ± 0.049	3.699GluSer: 3.699 ± 0.059	3.498GluThr: 3.498 ± 0.063	4.609GluVal: 4.609 ± 0.068	0.595GluTrp: 0.595 ± 0.022	3.435GluTyr: 3.435 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	2.488PheAla: 2.488 ± 0.053	0.469PheCys: 0.469 ± 0.022	2.499PheAsp: 2.499 ± 0.049	2.728PheGlu: 2.728 ± 0.048	1.776PhePhe: 1.776 ± 0.042	2.813PheGly: 2.813 ± 0.046	0.824PheHis: 0.824 ± 0.028	4.07PheIle: 4.07 ± 0.08	2.728PheLys: 2.728 ± 0.049	3.724PheLeu: 3.724 ± 0.068	1.118PheMet: 1.118 ± 0.033	2.246PheAsn: 2.246 ± 0.045	1.231PhePro: 1.231 ± 0.037	1.267PheGln: 1.267 ± 0.035	1.378PheArg: 1.378 ± 0.038	2.926PheSer: 2.926 ± 0.055	2.491PheThr: 2.491 ± 0.054	2.553PheVal: 2.553 ± 0.054	0.389PheTrp: 0.389 ± 0.019	1.764PheTyr: 1.764 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	4.319GlyAla: 4.319 ± 0.081	0.914GlyCys: 0.914 ± 0.031	3.363GlyAsp: 3.363 ± 0.062	4.466GlyGlu: 4.466 ± 0.068	3.07GlyPhe: 3.07 ± 0.058	4.319GlyGly: 4.319 ± 0.106	1.07GlyHis: 1.07 ± 0.032	7.106GlyIle: 7.106 ± 0.091	5.338GlyLys: 5.338 ± 0.078	5.588GlyLeu: 5.588 ± 0.077	2.035GlyMet: 2.035 ± 0.039	3.592GlyAsn: 3.592 ± 0.066	1.471GlyPro: 1.471 ± 0.106	1.728GlyGln: 1.728 ± 0.04	2.407GlyArg: 2.407 ± 0.052	3.936GlySer: 3.936 ± 0.077	3.894GlyThr: 3.894 ± 0.072	4.425GlyVal: 4.425 ± 0.061	0.591GlyTrp: 0.591 ± 0.032	3.217GlyTyr: 3.217 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	0.785HisAla: 0.785 ± 0.026	0.211HisCys: 0.211 ± 0.014	0.829HisAsp: 0.829 ± 0.028	0.952HisGlu: 0.952 ± 0.028	0.747HisPhe: 0.747 ± 0.023	1.159HisGly: 1.159 ± 0.035	0.353HisHis: 0.353 ± 0.019	1.58HisIle: 1.58 ± 0.037	1.061HisLys: 1.061 ± 0.03	1.393HisLeu: 1.393 ± 0.035	0.469HisMet: 0.469 ± 0.022	0.879HisAsn: 0.879 ± 0.029	0.664HisPro: 0.664 ± 0.026	0.495HisGln: 0.495 ± 0.02	0.591HisArg: 0.591 ± 0.024	0.967HisSer: 0.967 ± 0.029	0.813HisThr: 0.813 ± 0.028	0.886HisVal: 0.886 ± 0.025	0.148HisTrp: 0.148 ± 0.014	0.73HisTyr: 0.73 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.018IleAla: 6.018 ± 0.087	1.191IleCys: 1.191 ± 0.036	5.338IleAsp: 5.338 ± 0.071	6.375IleGlu: 6.375 ± 0.084	3.708IlePhe: 3.708 ± 0.06	6.174IleGly: 6.174 ± 0.085	1.622IleHis: 1.622 ± 0.038	8.712IleIle: 8.712 ± 0.124	6.896IleLys: 6.896 ± 0.074	8.865IleLeu: 8.865 ± 0.122	2.534IleMet: 2.534 ± 0.049	5.045IleAsn: 5.045 ± 0.083	3.568IlePro: 3.568 ± 0.055	2.651IleGln: 2.651 ± 0.055	3.364IleArg: 3.364 ± 0.056	6.705IleSer: 6.705 ± 0.094	5.65IleThr: 5.65 ± 0.071	5.693IleVal: 5.693 ± 0.08	0.634IleTrp: 0.634 ± 0.027	3.663IleTyr: 3.663 ± 0.062	0.0IleXaa: 0.0 ± 0.0
Lys	4.754LysAla: 4.754 ± 0.068	0.631LysCys: 0.631 ± 0.025	4.878LysAsp: 4.878 ± 0.065	8.191LysGlu: 8.191 ± 0.099	2.298LysPhe: 2.298 ± 0.05	4.571LysGly: 4.571 ± 0.061	1.051LysHis: 1.051 ± 0.03	6.6LysIle: 6.6 ± 0.088	6.836LysLys: 6.836 ± 0.082	6.45LysLeu: 6.45 ± 0.078	2.245LysMet: 2.245 ± 0.054	4.931LysAsn: 4.931 ± 0.071	1.935LysPro: 1.935 ± 0.04	2.415LysGln: 2.415 ± 0.046	2.899LysArg: 2.899 ± 0.049	4.299LysSer: 4.299 ± 0.064	4.014LysThr: 4.014 ± 0.061	4.92LysVal: 4.92 ± 0.071	0.608LysTrp: 0.608 ± 0.026	3.336LysTyr: 3.336 ± 0.051	0.0LysXaa: 0.0 ± 0.0
Leu	5.53LeuAla: 5.53 ± 0.071	1.133LeuCys: 1.133 ± 0.034	5.149LeuAsp: 5.149 ± 0.068	6.476LeuGlu: 6.476 ± 0.085	3.741LeuPhe: 3.741 ± 0.066	5.86LeuGly: 5.86 ± 0.074	1.279LeuHis: 1.279 ± 0.035	7.751LeuIle: 7.751 ± 0.116	7.081LeuLys: 7.081 ± 0.081	8.332LeuLeu: 8.332 ± 0.103	2.378LeuMet: 2.378 ± 0.05	5.23LeuAsn: 5.23 ± 0.072	3.12LeuPro: 3.12 ± 0.052	2.402LeuGln: 2.402 ± 0.047	3.199LeuArg: 3.199 ± 0.063	6.686LeuSer: 6.686 ± 0.073	4.838LeuThr: 4.838 ± 0.067	5.152LeuVal: 5.152 ± 0.069	0.644LeuTrp: 0.644 ± 0.023	3.386LeuTyr: 3.386 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	1.892MetAla: 1.892 ± 0.04	0.266MetCys: 0.266 ± 0.015	1.764MetAsp: 1.764 ± 0.038	2.272MetGlu: 2.272 ± 0.043	0.954MetPhe: 0.954 ± 0.029	1.788MetGly: 1.788 ± 0.045	0.353MetHis: 0.353 ± 0.018	2.437MetIle: 2.437 ± 0.052	2.71MetLys: 2.71 ± 0.054	2.399MetLeu: 2.399 ± 0.046	0.731MetMet: 0.731 ± 0.028	1.999MetAsn: 1.999 ± 0.041	0.962MetPro: 0.962 ± 0.034	0.752MetGln: 0.752 ± 0.027	0.917MetArg: 0.917 ± 0.03	1.734MetSer: 1.734 ± 0.044	1.446MetThr: 1.446 ± 0.037	1.757MetVal: 1.757 ± 0.038	0.165MetTrp: 0.165 ± 0.011	0.886MetTyr: 0.886 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.055AsnAla: 3.055 ± 0.051	0.576AsnCys: 0.576 ± 0.026	2.856AsnAsp: 2.856 ± 0.051	4.108AsnGlu: 4.108 ± 0.06	2.088AsnPhe: 2.088 ± 0.044	3.909AsnGly: 3.909 ± 0.077	0.992AsnHis: 0.992 ± 0.035	5.788AsnIle: 5.788 ± 0.08	4.262AsnLys: 4.262 ± 0.066	4.893AsnLeu: 4.893 ± 0.071	1.656AsnMet: 1.656 ± 0.039	3.558AsnAsn: 3.558 ± 0.078	2.149AsnPro: 2.149 ± 0.047	1.939AsnGln: 1.939 ± 0.05	2.136AsnArg: 2.136 ± 0.042	3.432AsnSer: 3.432 ± 0.065	3.04AsnThr: 3.04 ± 0.057	3.311AsnVal: 3.311 ± 0.05	0.443AsnTrp: 0.443 ± 0.022	2.639AsnTyr: 2.639 ± 0.056	0.0AsnXaa: 0.0 ± 0.0
Pro	1.878ProAla: 1.878 ± 0.054	0.346ProCys: 0.346 ± 0.02	2.024ProAsp: 2.024 ± 0.055	2.551ProGlu: 2.551 ± 0.047	1.424ProPhe: 1.424 ± 0.032	2.046ProGly: 2.046 ± 0.049	0.521ProHis: 0.521 ± 0.02	2.645ProIle: 2.645 ± 0.048	1.978ProLys: 1.978 ± 0.041	2.567ProLeu: 2.567 ± 0.053	0.779ProMet: 0.779 ± 0.028	1.446ProAsn: 1.446 ± 0.034	0.659ProPro: 0.659 ± 0.024	0.838ProGln: 0.838 ± 0.038	0.879ProArg: 0.879 ± 0.028	1.752ProSer: 1.752 ± 0.039	1.733ProThr: 1.733 ± 0.067	2.413ProVal: 2.413 ± 0.053	0.289ProTrp: 0.289 ± 0.017	1.386ProTyr: 1.386 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	1.795GlnAla: 1.795 ± 0.041	0.272GlnCys: 0.272 ± 0.015	1.403GlnAsp: 1.403 ± 0.037	2.022GlnGlu: 2.022 ± 0.045	1.183GlnPhe: 1.183 ± 0.032	1.806GlnGly: 1.806 ± 0.06	0.365GlnHis: 0.365 ± 0.018	2.768GlnIle: 2.768 ± 0.055	2.344GlnLys: 2.344 ± 0.045	2.703GlnLeu: 2.703 ± 0.048	0.921GlnMet: 0.921 ± 0.027	1.669GlnAsn: 1.669 ± 0.047	0.714GlnPro: 0.714 ± 0.026	0.827GlnGln: 0.827 ± 0.033	1.04GlnArg: 1.04 ± 0.033	1.64GlnSer: 1.64 ± 0.034	1.512GlnThr: 1.512 ± 0.041	1.782GlnVal: 1.782 ± 0.041	0.251GlnTrp: 0.251 ± 0.017	1.372GlnTyr: 1.372 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	1.933ArgAla: 1.933 ± 0.044	0.401ArgCys: 0.401 ± 0.023	1.875ArgAsp: 1.875 ± 0.044	2.966ArgGlu: 2.966 ± 0.056	1.55ArgPhe: 1.55 ± 0.035	2.049ArgGly: 2.049 ± 0.042	0.526ArgHis: 0.526 ± 0.023	3.466ArgIle: 3.466 ± 0.054	2.946ArgLys: 2.946 ± 0.046	3.144ArgLeu: 3.144 ± 0.053	1.14ArgMet: 1.14 ± 0.032	2.155ArgAsn: 2.155 ± 0.046	1.008ArgPro: 1.008 ± 0.032	1.105ArgGln: 1.105 ± 0.034	1.482ArgArg: 1.482 ± 0.041	1.801ArgSer: 1.801 ± 0.035	1.898ArgThr: 1.898 ± 0.041	2.099ArgVal: 2.099 ± 0.046	0.32ArgTrp: 0.32 ± 0.016	1.591ArgTyr: 1.591 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	3.52SerAla: 3.52 ± 0.063	0.624SerCys: 0.624 ± 0.024	3.445SerAsp: 3.445 ± 0.053	4.093SerGlu: 4.093 ± 0.067	2.953SerPhe: 2.953 ± 0.046	4.702SerGly: 4.702 ± 0.069	0.983SerHis: 0.983 ± 0.032	6.011SerIle: 6.011 ± 0.072	4.84SerLys: 4.84 ± 0.065	5.759SerLeu: 5.759 ± 0.08	1.756SerMet: 1.756 ± 0.042	3.607SerAsn: 3.607 ± 0.064	1.716SerPro: 1.716 ± 0.041	1.688SerGln: 1.688 ± 0.039	2.186SerArg: 2.186 ± 0.048	4.11SerSer: 4.11 ± 0.074	3.326SerThr: 3.326 ± 0.055	3.967SerVal: 3.967 ± 0.069	0.483SerTrp: 0.483 ± 0.024	2.718SerTyr: 2.718 ± 0.06	0.0SerXaa: 0.0 ± 0.0
Thr	3.631ThrAla: 3.631 ± 0.07	0.548ThrCys: 0.548 ± 0.022	3.093ThrAsp: 3.093 ± 0.06	3.405ThrGlu: 3.405 ± 0.057	2.283ThrPhe: 2.283 ± 0.039	4.427ThrGly: 4.427 ± 0.097	0.821ThrHis: 0.821 ± 0.026	5.142ThrIle: 5.142 ± 0.065	3.941ThrLys: 3.941 ± 0.066	5.071ThrLeu: 5.071 ± 0.07	1.474ThrMet: 1.474 ± 0.034	2.822ThrAsn: 2.822 ± 0.061	1.949ThrPro: 1.949 ± 0.041	1.366ThrGln: 1.366 ± 0.038	1.776ThrArg: 1.776 ± 0.037	3.385ThrSer: 3.385 ± 0.061	3.118ThrThr: 3.118 ± 0.059	4.066ThrVal: 4.066 ± 0.078	0.447ThrTrp: 0.447 ± 0.023	2.268ThrTyr: 2.268 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	4.164ValAla: 4.164 ± 0.068	0.776ValCys: 0.776 ± 0.027	3.629ValAsp: 3.629 ± 0.064	4.188ValGlu: 4.188 ± 0.07	2.614ValPhe: 2.614 ± 0.049	3.963ValGly: 3.963 ± 0.063	0.89ValHis: 0.89 ± 0.026	6.045ValIle: 6.045 ± 0.071	4.794ValLys: 4.794 ± 0.064	5.729ValLeu: 5.729 ± 0.072	1.703ValMet: 1.703 ± 0.041	3.466ValAsn: 3.466 ± 0.055	2.024ValPro: 2.024 ± 0.046	1.545ValGln: 1.545 ± 0.036	2.05ValArg: 2.05 ± 0.046	4.407ValSer: 4.407 ± 0.064	3.951ValThr: 3.951 ± 0.069	4.169ValVal: 4.169 ± 0.071	0.473ValTrp: 0.473 ± 0.027	2.524ValTyr: 2.524 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.404TrpAla: 0.404 ± 0.019	0.101TrpCys: 0.101 ± 0.011	0.48TrpAsp: 0.48 ± 0.021	0.543TrpGlu: 0.543 ± 0.024	0.386TrpPhe: 0.386 ± 0.018	0.57TrpGly: 0.57 ± 0.025	0.152TrpHis: 0.152 ± 0.012	0.663TrpIle: 0.663 ± 0.027	0.596TrpLys: 0.596 ± 0.026	0.711TrpLeu: 0.711 ± 0.023	0.259TrpMet: 0.259 ± 0.017	0.579TrpAsn: 0.579 ± 0.023	0.194TrpPro: 0.194 ± 0.014	0.274TrpGln: 0.274 ± 0.015	0.297TrpArg: 0.297 ± 0.016	0.5TrpSer: 0.5 ± 0.023	0.354TrpThr: 0.354 ± 0.019	0.431TrpVal: 0.431 ± 0.022	0.094TrpTrp: 0.094 ± 0.01	0.355TrpTyr: 0.355 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.214TyrAla: 2.214 ± 0.046	0.521TyrCys: 0.521 ± 0.022	2.633TyrAsp: 2.633 ± 0.046	3.051TyrGlu: 3.051 ± 0.053	1.998TyrPhe: 1.998 ± 0.05	3.007TyrGly: 3.007 ± 0.067	0.783TyrHis: 0.783 ± 0.025	3.961TyrIle: 3.961 ± 0.062	3.097TyrLys: 3.097 ± 0.055	3.749TyrLeu: 3.749 ± 0.06	1.061TyrMet: 1.061 ± 0.031	2.528TyrAsn: 2.528 ± 0.054	1.433TyrPro: 1.433 ± 0.04	1.432TyrGln: 1.432 ± 0.041	1.646TyrArg: 1.646 ± 0.039	2.766TyrSer: 2.766 ± 0.05	2.346TyrThr: 2.346 ± 0.055	2.434TyrVal: 2.434 ± 0.045	0.345TyrTrp: 0.345 ± 0.021	2.118TyrTyr: 2.118 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3612 proteins (1185076 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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