Amino acid dipepetide frequency for Kerstersia gyiorum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.064AlaAla: 17.064 ± 0.205	1.298AlaCys: 1.298 ± 0.035	6.402AlaAsp: 6.402 ± 0.074	6.282AlaGlu: 6.282 ± 0.092	3.89AlaPhe: 3.89 ± 0.063	11.41AlaGly: 11.41 ± 0.135	2.386AlaHis: 2.386 ± 0.052	5.588AlaIle: 5.588 ± 0.081	2.755AlaLys: 2.755 ± 0.09	14.797AlaLeu: 14.797 ± 0.143	3.386AlaMet: 3.386 ± 0.065	2.852AlaAsn: 2.852 ± 0.063	5.77AlaPro: 5.77 ± 0.1	5.824AlaGln: 5.824 ± 0.096	9.017AlaArg: 9.017 ± 0.107	7.071AlaSer: 7.071 ± 0.084	5.546AlaThr: 5.546 ± 0.086	8.427AlaVal: 8.427 ± 0.108	2.132AlaTrp: 2.132 ± 0.055	2.751AlaTyr: 2.751 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	1.04CysAla: 1.04 ± 0.03	0.139CysCys: 0.139 ± 0.011	0.456CysAsp: 0.456 ± 0.02	0.426CysGlu: 0.426 ± 0.02	0.327CysPhe: 0.327 ± 0.017	0.884CysGly: 0.884 ± 0.028	0.219CysHis: 0.219 ± 0.017	0.423CysIle: 0.423 ± 0.018	0.174CysLys: 0.174 ± 0.015	0.96CysLeu: 0.96 ± 0.032	0.221CysMet: 0.221 ± 0.012	0.216CysAsn: 0.216 ± 0.015	0.409CysPro: 0.409 ± 0.02	0.324CysGln: 0.324 ± 0.018	0.559CysArg: 0.559 ± 0.024	0.454CysSer: 0.454 ± 0.02	0.431CysThr: 0.431 ± 0.021	0.655CysVal: 0.655 ± 0.024	0.122CysTrp: 0.122 ± 0.009	0.228CysTyr: 0.228 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.889AspAla: 6.889 ± 0.1	0.41AspCys: 0.41 ± 0.019	2.749AspAsp: 2.749 ± 0.055	3.117AspGlu: 3.117 ± 0.063	1.998AspPhe: 1.998 ± 0.05	4.99AspGly: 4.99 ± 0.093	0.997AspHis: 0.997 ± 0.029	3.102AspIle: 3.102 ± 0.057	1.469AspLys: 1.469 ± 0.044	5.12AspLeu: 5.12 ± 0.074	1.29AspMet: 1.29 ± 0.033	1.431AspAsn: 1.431 ± 0.041	2.846AspPro: 2.846 ± 0.055	1.685AspGln: 1.685 ± 0.038	2.968AspArg: 2.968 ± 0.055	2.596AspSer: 2.596 ± 0.051	2.816AspThr: 2.816 ± 0.052	3.737AspVal: 3.737 ± 0.064	1.032AspTrp: 1.032 ± 0.032	1.558AspTyr: 1.558 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	6.475GluAla: 6.475 ± 0.089	0.363GluCys: 0.363 ± 0.017	2.513GluAsp: 2.513 ± 0.049	2.62GluGlu: 2.62 ± 0.055	1.729GluPhe: 1.729 ± 0.043	3.567GluGly: 3.567 ± 0.065	1.325GluHis: 1.325 ± 0.043	2.904GluIle: 2.904 ± 0.049	1.8GluLys: 1.8 ± 0.05	5.535GluLeu: 5.535 ± 0.081	1.189GluMet: 1.189 ± 0.033	1.66GluAsn: 1.66 ± 0.04	2.446GluPro: 2.446 ± 0.043	3.016GluGln: 3.016 ± 0.062	4.399GluArg: 4.399 ± 0.076	2.625GluSer: 2.625 ± 0.055	2.745GluThr: 2.745 ± 0.06	3.605GluVal: 3.605 ± 0.061	0.668GluTrp: 0.668 ± 0.023	1.264GluTyr: 1.264 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.677PheAla: 3.677 ± 0.052	0.36PheCys: 0.36 ± 0.021	2.247PheAsp: 2.247 ± 0.039	1.842PheGlu: 1.842 ± 0.047	1.337PhePhe: 1.337 ± 0.039	3.188PheGly: 3.188 ± 0.061	0.708PheHis: 0.708 ± 0.028	1.696PheIle: 1.696 ± 0.044	0.913PheLys: 0.913 ± 0.033	3.422PheLeu: 3.422 ± 0.072	0.9PheMet: 0.9 ± 0.032	1.182PheAsn: 1.182 ± 0.034	1.517PhePro: 1.517 ± 0.042	1.229PheGln: 1.229 ± 0.03	2.031PheArg: 2.031 ± 0.045	2.484PheSer: 2.484 ± 0.048	1.765PheThr: 1.765 ± 0.04	2.488PheVal: 2.488 ± 0.051	0.536PheTrp: 0.536 ± 0.023	0.919PheTyr: 0.919 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	9.084GlyAla: 9.084 ± 0.123	0.831GlyCys: 0.831 ± 0.031	3.927GlyAsp: 3.927 ± 0.077	4.225GlyGlu: 4.225 ± 0.069	3.089GlyPhe: 3.089 ± 0.067	6.811GlyGly: 6.811 ± 0.095	1.813GlyHis: 1.813 ± 0.041	4.455GlyIle: 4.455 ± 0.069	3.355GlyLys: 3.355 ± 0.062	9.747GlyLeu: 9.747 ± 0.117	2.577GlyMet: 2.577 ± 0.049	2.551GlyAsn: 2.551 ± 0.075	2.98GlyPro: 2.98 ± 0.055	3.715GlyGln: 3.715 ± 0.059	5.716GlyArg: 5.716 ± 0.079	4.846GlySer: 4.846 ± 0.096	4.366GlyThr: 4.366 ± 0.086	6.505GlyVal: 6.505 ± 0.087	1.509GlyTrp: 1.509 ± 0.039	2.371GlyTyr: 2.371 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.819HisAla: 2.819 ± 0.056	0.246HisCys: 0.246 ± 0.015	1.252HisAsp: 1.252 ± 0.036	1.113HisGlu: 1.113 ± 0.033	0.856HisPhe: 0.856 ± 0.028	2.207HisGly: 2.207 ± 0.044	0.578HisHis: 0.578 ± 0.026	1.116HisIle: 1.116 ± 0.035	0.457HisLys: 0.457 ± 0.023	2.111HisLeu: 2.111 ± 0.05	0.499HisMet: 0.499 ± 0.018	0.524HisAsn: 0.524 ± 0.02	1.409HisPro: 1.409 ± 0.04	0.787HisGln: 0.787 ± 0.029	1.312HisArg: 1.312 ± 0.037	1.031HisSer: 1.031 ± 0.035	0.982HisThr: 0.982 ± 0.028	1.477HisVal: 1.477 ± 0.038	0.383HisTrp: 0.383 ± 0.021	0.661HisTyr: 0.661 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.147IleAla: 6.147 ± 0.087	0.462IleCys: 0.462 ± 0.021	2.621IleAsp: 2.621 ± 0.052	2.949IleGlu: 2.949 ± 0.06	1.541IlePhe: 1.541 ± 0.044	4.376IleGly: 4.376 ± 0.081	0.932IleHis: 0.932 ± 0.032	2.142IleIle: 2.142 ± 0.053	1.388IleLys: 1.388 ± 0.039	4.429IleLeu: 4.429 ± 0.065	0.993IleMet: 0.993 ± 0.034	1.534IleAsn: 1.534 ± 0.042	2.26IlePro: 2.26 ± 0.046	1.577IleGln: 1.577 ± 0.041	2.952IleArg: 2.952 ± 0.055	2.965IleSer: 2.965 ± 0.049	2.425IleThr: 2.425 ± 0.044	3.696IleVal: 3.696 ± 0.065	0.594IleTrp: 0.594 ± 0.026	1.202IleTyr: 1.202 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	3.131LysAla: 3.131 ± 0.082	0.122LysCys: 0.122 ± 0.011	1.411LysAsp: 1.411 ± 0.049	1.433LysGlu: 1.433 ± 0.043	0.727LysPhe: 0.727 ± 0.027	2.05LysGly: 2.05 ± 0.052	0.586LysHis: 0.586 ± 0.023	1.299LysIle: 1.299 ± 0.039	0.942LysLys: 0.942 ± 0.039	3.016LysLeu: 3.016 ± 0.055	0.664LysMet: 0.664 ± 0.028	0.792LysAsn: 0.792 ± 0.027	1.666LysPro: 1.666 ± 0.044	1.2LysGln: 1.2 ± 0.035	1.888LysArg: 1.888 ± 0.051	1.418LysSer: 1.418 ± 0.035	1.594LysThr: 1.594 ± 0.045	2.2LysVal: 2.2 ± 0.057	0.346LysTrp: 0.346 ± 0.019	0.661LysTyr: 0.661 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	15.977LeuAla: 15.977 ± 0.176	1.042LeuCys: 1.042 ± 0.032	6.449LeuAsp: 6.449 ± 0.084	5.797LeuGlu: 5.797 ± 0.096	3.685LeuPhe: 3.685 ± 0.073	9.109LeuGly: 9.109 ± 0.113	2.311LeuHis: 2.311 ± 0.044	4.564LeuIle: 4.564 ± 0.075	3.039LeuLys: 3.039 ± 0.062	12.569LeuLeu: 12.569 ± 0.187	2.55LeuMet: 2.55 ± 0.045	2.826LeuAsn: 2.826 ± 0.055	6.612LeuPro: 6.612 ± 0.089	4.409LeuGln: 4.409 ± 0.073	7.995LeuArg: 7.995 ± 0.104	6.75LeuSer: 6.75 ± 0.082	5.276LeuThr: 5.276 ± 0.073	7.645LeuVal: 7.645 ± 0.093	1.296LeuTrp: 1.296 ± 0.034	2.353LeuTyr: 2.353 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.044MetAla: 3.044 ± 0.052	0.125MetCys: 0.125 ± 0.01	1.147MetAsp: 1.147 ± 0.03	1.101MetGlu: 1.101 ± 0.036	0.72MetPhe: 0.72 ± 0.026	1.877MetGly: 1.877 ± 0.043	0.52MetHis: 0.52 ± 0.022	1.062MetIle: 1.062 ± 0.033	0.791MetLys: 0.791 ± 0.029	2.922MetLeu: 2.922 ± 0.06	0.651MetMet: 0.651 ± 0.028	0.778MetAsn: 0.778 ± 0.022	1.529MetPro: 1.529 ± 0.038	1.175MetGln: 1.175 ± 0.032	1.79MetArg: 1.79 ± 0.045	1.608MetSer: 1.608 ± 0.037	1.52MetThr: 1.52 ± 0.045	1.721MetVal: 1.721 ± 0.044	0.192MetTrp: 0.192 ± 0.014	0.37MetTyr: 0.37 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.168AsnAla: 3.168 ± 0.059	0.189AsnCys: 0.189 ± 0.013	1.421AsnAsp: 1.421 ± 0.034	1.319AsnGlu: 1.319 ± 0.035	0.986AsnPhe: 0.986 ± 0.031	2.453AsnGly: 2.453 ± 0.063	0.576AsnHis: 0.576 ± 0.02	1.419AsnIle: 1.419 ± 0.042	0.732AsnLys: 0.732 ± 0.033	2.858AsnLeu: 2.858 ± 0.057	0.644AsnMet: 0.644 ± 0.025	0.832AsnAsn: 0.832 ± 0.037	1.794AsnPro: 1.794 ± 0.04	0.995AsnGln: 0.995 ± 0.036	1.748AsnArg: 1.748 ± 0.044	1.353AsnSer: 1.353 ± 0.054	1.595AsnThr: 1.595 ± 0.05	2.026AsnVal: 2.026 ± 0.07	0.453AsnTrp: 0.453 ± 0.021	0.775AsnTyr: 0.775 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	7.236ProAla: 7.236 ± 0.108	0.379ProCys: 0.379 ± 0.02	3.412ProAsp: 3.412 ± 0.065	3.516ProGlu: 3.516 ± 0.063	1.682ProPhe: 1.682 ± 0.04	4.868ProGly: 4.868 ± 0.073	1.068ProHis: 1.068 ± 0.029	1.806ProIle: 1.806 ± 0.042	1.077ProLys: 1.077 ± 0.033	5.311ProLeu: 5.311 ± 0.077	1.157ProMet: 1.157 ± 0.036	1.231ProAsn: 1.231 ± 0.032	2.306ProPro: 2.306 ± 0.062	2.063ProGln: 2.063 ± 0.042	2.834ProArg: 2.834 ± 0.058	2.684ProSer: 2.684 ± 0.047	2.125ProThr: 2.125 ± 0.053	4.345ProVal: 4.345 ± 0.072	0.812ProTrp: 0.812 ± 0.026	1.221ProTyr: 1.221 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	7.067GlnAla: 7.067 ± 0.098	0.258GlnCys: 0.258 ± 0.016	2.054GlnAsp: 2.054 ± 0.042	2.154GlnGlu: 2.154 ± 0.042	1.187GlnPhe: 1.187 ± 0.032	3.6GlnGly: 3.6 ± 0.069	1.014GlnHis: 1.014 ± 0.035	1.839GlnIle: 1.839 ± 0.036	0.952GlnLys: 0.952 ± 0.034	4.276GlnLeu: 4.276 ± 0.065	0.917GlnMet: 0.917 ± 0.028	0.962GlnAsn: 0.962 ± 0.034	2.42GlnPro: 2.42 ± 0.053	2.336GlnGln: 2.336 ± 0.058	3.64GlnArg: 3.64 ± 0.068	2.022GlnSer: 2.022 ± 0.044	1.795GlnThr: 1.795 ± 0.049	3.167GlnVal: 3.167 ± 0.06	0.74GlnTrp: 0.74 ± 0.025	0.874GlnTyr: 0.874 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	7.173ArgAla: 7.173 ± 0.087	0.543ArgCys: 0.543 ± 0.023	3.63ArgAsp: 3.63 ± 0.062	4.019ArgGlu: 4.019 ± 0.074	2.585ArgPhe: 2.585 ± 0.049	4.517ArgGly: 4.517 ± 0.061	2.026ArgHis: 2.026 ± 0.057	3.778ArgIle: 3.778 ± 0.066	2.053ArgLys: 2.053 ± 0.05	8.384ArgLeu: 8.384 ± 0.108	1.796ArgMet: 1.796 ± 0.038	2.057ArgAsn: 2.057 ± 0.049	3.263ArgPro: 3.263 ± 0.059	3.927ArgGln: 3.927 ± 0.068	5.533ArgArg: 5.533 ± 0.087	3.531ArgSer: 3.531 ± 0.057	3.232ArgThr: 3.232 ± 0.059	4.613ArgVal: 4.613 ± 0.079	1.109ArgTrp: 1.109 ± 0.034	2.25ArgTyr: 2.25 ± 0.051	0.001ArgXaa: 0.001 ± 0.001
Ser	6.242SerAla: 6.242 ± 0.086	0.431SerCys: 0.431 ± 0.02	2.567SerAsp: 2.567 ± 0.051	2.429SerGlu: 2.429 ± 0.047	2.153SerPhe: 2.153 ± 0.044	5.61SerGly: 5.61 ± 0.082	1.24SerHis: 1.24 ± 0.036	2.608SerIle: 2.608 ± 0.053	1.374SerLys: 1.374 ± 0.04	6.455SerLeu: 6.455 ± 0.092	1.444SerMet: 1.444 ± 0.035	1.56SerAsn: 1.56 ± 0.05	2.719SerPro: 2.719 ± 0.049	2.297SerGln: 2.297 ± 0.046	3.841SerArg: 3.841 ± 0.064	3.361SerSer: 3.361 ± 0.068	2.849SerThr: 2.849 ± 0.067	4.202SerVal: 4.202 ± 0.078	0.887SerTrp: 0.887 ± 0.033	1.535SerTyr: 1.535 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.369ThrAla: 5.369 ± 0.077	0.38ThrCys: 0.38 ± 0.021	2.519ThrAsp: 2.519 ± 0.058	2.296ThrGlu: 2.296 ± 0.041	1.622ThrPhe: 1.622 ± 0.039	4.64ThrGly: 4.64 ± 0.067	1.117ThrHis: 1.117 ± 0.033	2.189ThrIle: 2.189 ± 0.05	0.972ThrLys: 0.972 ± 0.032	6.652ThrLeu: 6.652 ± 0.08	0.989ThrMet: 0.989 ± 0.031	1.185ThrAsn: 1.185 ± 0.047	3.388ThrPro: 3.388 ± 0.059	1.885ThrGln: 1.885 ± 0.04	3.391ThrArg: 3.391 ± 0.056	2.533ThrSer: 2.533 ± 0.051	2.404ThrThr: 2.404 ± 0.054	3.967ThrVal: 3.967 ± 0.074	0.648ThrTrp: 0.648 ± 0.022	1.111ThrTyr: 1.111 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	8.867ValAla: 8.867 ± 0.119	0.688ValCys: 0.688 ± 0.03	3.896ValAsp: 3.896 ± 0.06	3.857ValGlu: 3.857 ± 0.067	2.805ValPhe: 2.805 ± 0.05	5.173ValGly: 5.173 ± 0.083	1.438ValHis: 1.438 ± 0.039	3.518ValIle: 3.518 ± 0.059	1.921ValLys: 1.921 ± 0.055	8.633ValLeu: 8.633 ± 0.103	1.847ValMet: 1.847 ± 0.042	2.033ValAsn: 2.033 ± 0.061	3.863ValPro: 3.863 ± 0.055	2.837ValGln: 2.837 ± 0.049	4.973ValArg: 4.973 ± 0.071	4.406ValSer: 4.406 ± 0.075	3.878ValThr: 3.878 ± 0.065	5.596ValVal: 5.596 ± 0.082	0.882ValTrp: 0.882 ± 0.031	1.703ValTyr: 1.703 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	1.267TrpAla: 1.267 ± 0.033	0.145TrpCys: 0.145 ± 0.011	0.621TrpAsp: 0.621 ± 0.024	0.631TrpGlu: 0.631 ± 0.024	0.561TrpPhe: 0.561 ± 0.024	0.889TrpGly: 0.889 ± 0.03	0.433TrpHis: 0.433 ± 0.023	0.673TrpIle: 0.673 ± 0.028	0.422TrpLys: 0.422 ± 0.02	2.378TrpLeu: 2.378 ± 0.056	0.44TrpMet: 0.44 ± 0.02	0.477TrpAsn: 0.477 ± 0.024	0.721TrpPro: 0.721 ± 0.028	0.948TrpGln: 0.948 ± 0.032	1.405TrpArg: 1.405 ± 0.044	0.76TrpSer: 0.76 ± 0.025	0.64TrpThr: 0.64 ± 0.025	1.013TrpVal: 1.013 ± 0.033	0.233TrpTrp: 0.233 ± 0.016	0.33TrpTyr: 0.33 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.913TyrAla: 2.913 ± 0.05	0.257TyrCys: 0.257 ± 0.016	1.505TyrAsp: 1.505 ± 0.038	1.321TyrGlu: 1.321 ± 0.038	0.962TyrPhe: 0.962 ± 0.031	2.254TyrGly: 2.254 ± 0.047	0.534TyrHis: 0.534 ± 0.024	1.004TyrIle: 1.004 ± 0.033	0.56TyrLys: 0.56 ± 0.025	2.68TyrLeu: 2.68 ± 0.049	0.489TyrMet: 0.489 ± 0.024	0.654TyrAsn: 0.654 ± 0.026	1.215TyrPro: 1.215 ± 0.035	1.043TyrGln: 1.043 ± 0.03	2.029TyrArg: 2.029 ± 0.044	1.306TyrSer: 1.306 ± 0.041	1.275TyrThr: 1.275 ± 0.039	1.727TyrVal: 1.727 ± 0.042	0.413TyrTrp: 0.413 ± 0.02	0.704TyrTyr: 0.704 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 3267 proteins (1083391 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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