Amino acid dipepetide frequency for Eptesicus serotinus papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.065AlaAla: 5.065 ± 1.055
0.422AlaCys: 0.422 ± 0.326
3.377AlaAsp: 3.377 ± 0.381
3.799AlaGlu: 3.799 ± 1.266
4.221AlaPhe: 4.221 ± 0.936
3.377AlaGly: 3.377 ± 0.956
0.0AlaHis: 0.0 ± 0.0
2.111AlaIle: 2.111 ± 0.489
3.799AlaLys: 3.799 ± 2.265
5.91AlaLeu: 5.91 ± 2.204
0.422AlaMet: 0.422 ± 0.326
2.111AlaAsn: 2.111 ± 1.002
4.643AlaPro: 4.643 ± 1.198
1.688AlaGln: 1.688 ± 0.78
4.221AlaArg: 4.221 ± 1.626
2.955AlaSer: 2.955 ± 0.954
4.221AlaThr: 4.221 ± 1.46
2.955AlaVal: 2.955 ± 0.645
0.844AlaTrp: 0.844 ± 0.438
0.844AlaTyr: 0.844 ± 0.652
0.0AlaXaa: 0.0 ± 0.0
Cys
1.688CysAla: 1.688 ± 1.047
0.422CysCys: 0.422 ± 0.472
0.844CysAsp: 0.844 ± 0.56
0.422CysGlu: 0.422 ± 0.326
0.422CysPhe: 0.422 ± 0.472
0.422CysGly: 0.422 ± 0.472
0.0CysHis: 0.0 ± 0.0
0.844CysIle: 0.844 ± 0.675
0.844CysLys: 0.844 ± 0.775
2.111CysLeu: 2.111 ± 1.337
0.422CysMet: 0.422 ± 0.472
0.422CysAsn: 0.422 ± 0.54
1.688CysPro: 1.688 ± 0.831
0.0CysGln: 0.0 ± 0.0
0.844CysArg: 0.844 ± 0.565
1.266CysSer: 1.266 ± 0.792
1.266CysThr: 1.266 ± 0.792
1.266CysVal: 1.266 ± 1.15
0.422CysTrp: 0.422 ± 0.326
0.844CysTyr: 0.844 ± 0.555
0.0CysXaa: 0.0 ± 0.0
Asp
3.377AspAla: 3.377 ± 1.246
0.844AspCys: 0.844 ± 0.56
2.955AspAsp: 2.955 ± 1.25
5.065AspGlu: 5.065 ± 1.562
2.111AspPhe: 2.111 ± 0.799
3.377AspGly: 3.377 ± 1.003
2.955AspHis: 2.955 ± 0.715
6.332AspIle: 6.332 ± 3.608
2.955AspLys: 2.955 ± 1.057
5.91AspLeu: 5.91 ± 0.713
2.111AspMet: 2.111 ± 1.26
3.377AspAsn: 3.377 ± 1.208
3.799AspPro: 3.799 ± 1.564
2.533AspGln: 2.533 ± 0.473
1.688AspArg: 1.688 ± 1.181
7.598AspSer: 7.598 ± 1.271
3.799AspThr: 3.799 ± 2.217
4.643AspVal: 4.643 ± 1.126
0.422AspTrp: 0.422 ± 0.388
0.844AspTyr: 0.844 ± 0.466
0.0AspXaa: 0.0 ± 0.0
Glu
5.488GluAla: 5.488 ± 0.976
0.422GluCys: 0.422 ± 0.326
5.488GluAsp: 5.488 ± 2.242
6.754GluGlu: 6.754 ± 1.503
2.955GluPhe: 2.955 ± 0.957
4.643GluGly: 4.643 ± 1.343
0.844GluHis: 0.844 ± 0.589
3.377GluIle: 3.377 ± 1.478
2.533GluLys: 2.533 ± 1.037
3.799GluLeu: 3.799 ± 1.028
1.266GluMet: 1.266 ± 0.685
3.377GluAsn: 3.377 ± 1.372
3.799GluPro: 3.799 ± 1.366
3.799GluGln: 3.799 ± 1.173
3.799GluArg: 3.799 ± 1.158
2.955GluSer: 2.955 ± 0.815
1.688GluThr: 1.688 ± 1.136
2.111GluVal: 2.111 ± 0.895
1.266GluTrp: 1.266 ± 0.729
2.533GluTyr: 2.533 ± 0.879
0.0GluXaa: 0.0 ± 0.0
Phe
2.533PheAla: 2.533 ± 0.759
0.0PheCys: 0.0 ± 0.0
4.221PheAsp: 4.221 ± 0.9
2.111PheGlu: 2.111 ± 0.817
2.955PhePhe: 2.955 ± 1.309
3.377PheGly: 3.377 ± 0.381
0.844PheHis: 0.844 ± 0.438
2.955PheIle: 2.955 ± 0.957
1.266PheLys: 1.266 ± 0.685
4.643PheLeu: 4.643 ± 1.504
1.266PheMet: 1.266 ± 0.563
2.111PheAsn: 2.111 ± 0.957
1.266PhePro: 1.266 ± 0.625
2.955PheGln: 2.955 ± 1.032
2.955PheArg: 2.955 ± 0.429
4.643PheSer: 4.643 ± 1.416
1.266PheThr: 1.266 ± 0.594
2.533PheVal: 2.533 ± 0.957
2.111PheTrp: 2.111 ± 0.981
2.533PheTyr: 2.533 ± 0.58
0.0PheXaa: 0.0 ± 0.0
Gly
4.221GlyAla: 4.221 ± 0.906
1.688GlyCys: 1.688 ± 0.741
3.799GlyAsp: 3.799 ± 1.331
3.377GlyGlu: 3.377 ± 0.908
0.844GlyPhe: 0.844 ± 0.589
3.799GlyGly: 3.799 ± 2.186
2.111GlyHis: 2.111 ± 0.945
2.955GlyIle: 2.955 ± 1.618
2.533GlyLys: 2.533 ± 0.998
9.287GlyLeu: 9.287 ± 2.115
0.422GlyMet: 0.422 ± 0.388
2.955GlyAsn: 2.955 ± 1.501
2.955GlyPro: 2.955 ± 1.181
2.111GlyGln: 2.111 ± 0.739
6.332GlyArg: 6.332 ± 2.402
5.91GlySer: 5.91 ± 1.346
4.643GlyThr: 4.643 ± 2.432
3.377GlyVal: 3.377 ± 1.511
0.844GlyTrp: 0.844 ± 0.652
1.266GlyTyr: 1.266 ± 0.444
0.0GlyXaa: 0.0 ± 0.0
His
1.266HisAla: 1.266 ± 0.572
0.844HisCys: 0.844 ± 0.589
0.422HisAsp: 0.422 ± 0.415
0.422HisGlu: 0.422 ± 0.357
0.844HisPhe: 0.844 ± 0.396
0.422HisGly: 0.422 ± 0.415
0.0HisHis: 0.0 ± 0.0
0.844HisIle: 0.844 ± 0.445
0.0HisLys: 0.0 ± 0.0
1.688HisLeu: 1.688 ± 0.614
0.422HisMet: 0.422 ± 0.388
0.0HisAsn: 0.0 ± 0.0
1.266HisPro: 1.266 ± 0.33
0.422HisGln: 0.422 ± 0.326
1.266HisArg: 1.266 ± 0.785
2.533HisSer: 2.533 ± 0.805
1.688HisThr: 1.688 ± 0.719
2.111HisVal: 2.111 ± 0.343
0.844HisTrp: 0.844 ± 0.555
1.266HisTyr: 1.266 ± 0.33
0.0HisXaa: 0.0 ± 0.0
Ile
1.688IleAla: 1.688 ± 0.911
0.844IleCys: 0.844 ± 0.565
4.221IleAsp: 4.221 ± 2.575
3.377IleGlu: 3.377 ± 1.838
2.533IlePhe: 2.533 ± 0.953
5.488IleGly: 5.488 ± 2.841
1.266IleHis: 1.266 ± 0.33
1.266IleIle: 1.266 ± 0.75
1.688IleLys: 1.688 ± 0.835
3.799IleLeu: 3.799 ± 1.7
0.422IleMet: 0.422 ± 0.357
0.844IleAsn: 0.844 ± 0.56
2.533IlePro: 2.533 ± 1.982
3.377IleGln: 3.377 ± 1.47
2.533IleArg: 2.533 ± 0.908
2.533IleSer: 2.533 ± 0.418
4.221IleThr: 4.221 ± 1.492
5.065IleVal: 5.065 ± 1.892
0.844IleTrp: 0.844 ± 0.466
1.266IleTyr: 1.266 ± 0.444
0.0IleXaa: 0.0 ± 0.0
Lys
3.799LysAla: 3.799 ± 1.016
2.111LysCys: 2.111 ± 0.699
2.955LysAsp: 2.955 ± 1.337
1.266LysGlu: 1.266 ± 0.625
2.955LysPhe: 2.955 ± 1.501
3.799LysGly: 3.799 ± 1.632
1.688LysHis: 1.688 ± 0.876
2.955LysIle: 2.955 ± 0.716
2.955LysLys: 2.955 ± 0.934
1.688LysLeu: 1.688 ± 0.911
0.422LysMet: 0.422 ± 0.357
2.533LysAsn: 2.533 ± 0.62
1.266LysPro: 1.266 ± 0.723
0.422LysGln: 0.422 ± 0.388
3.377LysArg: 3.377 ± 0.703
4.643LysSer: 4.643 ± 1.273
1.688LysThr: 1.688 ± 0.979
4.643LysVal: 4.643 ± 0.972
0.422LysTrp: 0.422 ± 0.357
1.266LysTyr: 1.266 ± 0.374
0.0LysXaa: 0.0 ± 0.0
Leu
6.332LeuAla: 6.332 ± 1.155
1.266LeuCys: 1.266 ± 0.772
5.065LeuAsp: 5.065 ± 1.233
4.643LeuGlu: 4.643 ± 1.349
7.598LeuPhe: 7.598 ± 1.162
4.643LeuGly: 4.643 ± 1.161
1.266LeuHis: 1.266 ± 0.595
2.533LeuIle: 2.533 ± 1.502
5.065LeuLys: 5.065 ± 2.049
7.598LeuLeu: 7.598 ± 2.507
1.688LeuMet: 1.688 ± 0.923
3.799LeuAsn: 3.799 ± 1.368
4.221LeuPro: 4.221 ± 1.513
7.598LeuGln: 7.598 ± 1.765
5.91LeuArg: 5.91 ± 1.321
7.176LeuSer: 7.176 ± 1.534
3.799LeuThr: 3.799 ± 1.772
5.488LeuVal: 5.488 ± 1.864
0.422LeuTrp: 0.422 ± 0.357
1.688LeuTyr: 1.688 ± 0.543
0.0LeuXaa: 0.0 ± 0.0
Met
2.111MetAla: 2.111 ± 1.102
0.0MetCys: 0.0 ± 0.0
0.844MetAsp: 0.844 ± 0.466
0.844MetGlu: 0.844 ± 0.438
1.688MetPhe: 1.688 ± 0.705
0.422MetGly: 0.422 ± 0.388
0.0MetHis: 0.0 ± 0.0
0.844MetIle: 0.844 ± 0.652
1.266MetLys: 1.266 ± 0.978
0.844MetLeu: 0.844 ± 0.764
0.422MetMet: 0.422 ± 0.54
0.0MetAsn: 0.0 ± 0.0
0.844MetPro: 0.844 ± 0.714
0.0MetGln: 0.0 ± 0.0
1.266MetArg: 1.266 ± 0.625
2.533MetSer: 2.533 ± 0.835
0.422MetThr: 0.422 ± 0.326
2.955MetVal: 2.955 ± 0.638
0.0MetTrp: 0.0 ± 0.0
1.266MetTyr: 1.266 ± 0.839
0.0MetXaa: 0.0 ± 0.0
Asn
1.688AsnAla: 1.688 ± 0.979
0.0AsnCys: 0.0 ± 0.0
1.688AsnAsp: 1.688 ± 0.514
1.688AsnGlu: 1.688 ± 1.305
1.688AsnPhe: 1.688 ± 0.78
0.844AsnGly: 0.844 ± 0.775
0.844AsnHis: 0.844 ± 0.764
2.111AsnIle: 2.111 ± 1.115
2.111AsnLys: 2.111 ± 0.504
3.377AsnLeu: 3.377 ± 1.054
0.844AsnMet: 0.844 ± 0.405
3.377AsnAsn: 3.377 ± 0.835
2.533AsnPro: 2.533 ± 1.501
1.688AsnGln: 1.688 ± 0.623
1.688AsnArg: 1.688 ± 1.188
2.533AsnSer: 2.533 ± 1.062
4.643AsnThr: 4.643 ± 0.718
2.111AsnVal: 2.111 ± 1.002
0.0AsnTrp: 0.0 ± 0.0
1.688AsnTyr: 1.688 ± 0.462
0.0AsnXaa: 0.0 ± 0.0
Pro
2.533ProAla: 2.533 ± 0.57
0.422ProCys: 0.422 ± 0.54
5.488ProAsp: 5.488 ± 1.51
4.643ProGlu: 4.643 ± 1.458
3.799ProPhe: 3.799 ± 0.64
3.799ProGly: 3.799 ± 1.861
0.422ProHis: 0.422 ± 0.415
3.799ProIle: 3.799 ± 1.628
2.955ProLys: 2.955 ± 0.953
4.221ProLeu: 4.221 ± 1.225
0.422ProMet: 0.422 ± 0.326
1.688ProAsn: 1.688 ± 0.614
5.065ProPro: 5.065 ± 0.648
2.111ProGln: 2.111 ± 1.102
4.221ProArg: 4.221 ± 1.547
6.754ProSer: 6.754 ± 3.27
2.955ProThr: 2.955 ± 1.066
2.111ProVal: 2.111 ± 1.107
0.0ProTrp: 0.0 ± 0.0
1.688ProTyr: 1.688 ± 1.1
0.0ProXaa: 0.0 ± 0.0
Gln
2.111GlnAla: 2.111 ± 0.752
0.844GlnCys: 0.844 ± 0.675
3.377GlnAsp: 3.377 ± 0.839
2.955GlnGlu: 2.955 ± 0.716
1.688GlnPhe: 1.688 ± 0.911
1.688GlnGly: 1.688 ± 0.81
0.844GlnHis: 0.844 ± 0.652
1.266GlnIle: 1.266 ± 0.563
2.955GlnLys: 2.955 ± 1.25
4.643GlnLeu: 4.643 ± 1.843
1.266GlnMet: 1.266 ± 0.548
0.844GlnAsn: 0.844 ± 0.775
1.688GlnPro: 1.688 ± 0.602
2.533GlnGln: 2.533 ± 1.195
2.111GlnArg: 2.111 ± 0.946
2.955GlnSer: 2.955 ± 0.82
2.955GlnThr: 2.955 ± 1.396
3.799GlnVal: 3.799 ± 0.722
0.844GlnTrp: 0.844 ± 0.438
1.266GlnTyr: 1.266 ± 0.692
0.0GlnXaa: 0.0 ± 0.0
Arg
4.221ArgAla: 4.221 ± 1.292
1.266ArgCys: 1.266 ± 0.792
3.377ArgAsp: 3.377 ± 0.894
5.065ArgGlu: 5.065 ± 1.598
2.955ArgPhe: 2.955 ± 0.992
4.643ArgGly: 4.643 ± 0.583
1.266ArgHis: 1.266 ± 0.839
2.533ArgIle: 2.533 ± 0.515
2.955ArgLys: 2.955 ± 1.066
6.754ArgLeu: 6.754 ± 1.447
0.422ArgMet: 0.422 ± 0.388
2.111ArgAsn: 2.111 ± 1.063
4.221ArgPro: 4.221 ± 1.936
3.799ArgGln: 3.799 ± 1.08
9.287ArgArg: 9.287 ± 2.76
8.02ArgSer: 8.02 ± 4.209
4.643ArgThr: 4.643 ± 0.946
2.955ArgVal: 2.955 ± 1.36
0.0ArgTrp: 0.0 ± 0.0
2.111ArgTyr: 2.111 ± 0.343
0.0ArgXaa: 0.0 ± 0.0
Ser
3.799SerAla: 3.799 ± 1.069
1.266SerCys: 1.266 ± 0.563
8.442SerAsp: 8.442 ± 2.421
3.799SerGlu: 3.799 ± 1.122
4.643SerPhe: 4.643 ± 1.3
6.332SerGly: 6.332 ± 2.149
1.688SerHis: 1.688 ± 0.543
3.799SerIle: 3.799 ± 1.112
2.955SerLys: 2.955 ± 1.381
8.864SerLeu: 8.864 ± 1.141
1.688SerMet: 1.688 ± 0.623
1.688SerAsn: 1.688 ± 0.911
5.91SerPro: 5.91 ± 2.392
2.533SerGln: 2.533 ± 0.902
10.975SerArg: 10.975 ± 4.959
8.02SerSer: 8.02 ± 4.153
5.488SerThr: 5.488 ± 0.998
3.377SerVal: 3.377 ± 1.692
0.422SerTrp: 0.422 ± 0.326
1.266SerTyr: 1.266 ± 0.584
0.0SerXaa: 0.0 ± 0.0
Thr
1.688ThrAla: 1.688 ± 0.76
0.844ThrCys: 0.844 ± 0.596
3.799ThrAsp: 3.799 ± 0.68
4.643ThrGlu: 4.643 ± 1.231
1.688ThrPhe: 1.688 ± 0.705
8.02ThrGly: 8.02 ± 1.18
0.422ThrHis: 0.422 ± 0.415
3.377ThrIle: 3.377 ± 1.304
1.266ThrLys: 1.266 ± 0.798
3.799ThrLeu: 3.799 ± 1.278
2.955ThrMet: 2.955 ± 1.832
1.266ThrAsn: 1.266 ± 0.595
4.643ThrPro: 4.643 ± 1.806
0.844ThrGln: 0.844 ± 0.596
2.955ThrArg: 2.955 ± 0.617
5.065ThrSer: 5.065 ± 1.529
3.377ThrThr: 3.377 ± 0.826
7.598ThrVal: 7.598 ± 1.036
0.844ThrTrp: 0.844 ± 0.405
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.266ValAla: 1.266 ± 0.625
1.688ValCys: 1.688 ± 1.13
4.221ValAsp: 4.221 ± 1.091
5.91ValGlu: 5.91 ± 1.512
1.688ValPhe: 1.688 ± 0.462
3.799ValGly: 3.799 ± 1.169
0.844ValHis: 0.844 ± 0.589
4.221ValIle: 4.221 ± 2.074
4.643ValLys: 4.643 ± 1.034
3.377ValLeu: 3.377 ± 1.058
0.422ValMet: 0.422 ± 0.357
3.377ValAsn: 3.377 ± 1.046
5.488ValPro: 5.488 ± 2.298
1.688ValGln: 1.688 ± 0.719
4.643ValArg: 4.643 ± 1.582
6.754ValSer: 6.754 ± 1.004
4.221ValThr: 4.221 ± 0.98
2.955ValVal: 2.955 ± 1.499
0.844ValTrp: 0.844 ± 0.775
1.688ValTyr: 1.688 ± 0.712
0.0ValXaa: 0.0 ± 0.0
Trp
0.844TrpAla: 0.844 ± 0.405
0.422TrpCys: 0.422 ± 0.326
1.266TrpAsp: 1.266 ± 0.798
0.422TrpGlu: 0.422 ± 0.388
0.422TrpPhe: 0.422 ± 0.357
0.0TrpGly: 0.0 ± 0.0
0.844TrpHis: 0.844 ± 0.405
0.844TrpIle: 0.844 ± 0.652
0.422TrpLys: 0.422 ± 0.326
2.533TrpLeu: 2.533 ± 0.879
0.0TrpMet: 0.0 ± 0.0
0.422TrpAsn: 0.422 ± 0.326
0.0TrpPro: 0.0 ± 0.0
0.844TrpGln: 0.844 ± 0.555
0.422TrpArg: 0.422 ± 0.388
0.844TrpSer: 0.844 ± 0.445
0.844TrpThr: 0.844 ± 0.714
0.422TrpVal: 0.422 ± 0.326
0.0TrpTrp: 0.0 ± 0.0
0.844TrpTyr: 0.844 ± 0.652
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.266TyrAla: 1.266 ± 0.563
0.844TyrCys: 0.844 ± 0.945
0.844TyrAsp: 0.844 ± 0.466
1.688TyrGlu: 1.688 ± 0.631
0.844TyrPhe: 0.844 ± 0.396
2.533TyrGly: 2.533 ± 0.749
0.422TyrHis: 0.422 ± 0.388
0.844TyrIle: 0.844 ± 0.405
1.688TyrLys: 1.688 ± 0.718
2.955TyrLeu: 2.955 ± 0.952
0.844TyrMet: 0.844 ± 0.78
0.844TyrAsn: 0.844 ± 0.438
1.266TyrPro: 1.266 ± 0.793
1.688TyrGln: 1.688 ± 0.718
2.111TyrArg: 2.111 ± 0.489
1.266TyrSer: 1.266 ± 0.451
1.266TyrThr: 1.266 ± 0.692
1.266TyrVal: 1.266 ± 0.783
1.266TyrTrp: 1.266 ± 0.798
1.688TyrTyr: 1.688 ± 0.657
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2370 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski