Amino acid dipepetide frequency for Liberibacter phage SC1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.145AlaAla: 2.145 ± 0.484
1.072AlaCys: 1.072 ± 0.367
3.794AlaAsp: 3.794 ± 0.602
3.877AlaGlu: 3.877 ± 0.645
2.392AlaPhe: 2.392 ± 0.37
4.619AlaGly: 4.619 ± 0.773
2.31AlaHis: 2.31 ± 0.389
3.3AlaIle: 3.3 ± 0.51
5.692AlaLys: 5.692 ± 0.713
6.434AlaLeu: 6.434 ± 0.865
1.732AlaMet: 1.732 ± 0.351
2.887AlaAsn: 2.887 ± 0.549
2.062AlaPro: 2.062 ± 0.485
2.392AlaGln: 2.392 ± 0.436
3.794AlaArg: 3.794 ± 0.514
5.774AlaSer: 5.774 ± 0.727
4.454AlaThr: 4.454 ± 0.962
5.444AlaVal: 5.444 ± 0.851
1.155AlaTrp: 1.155 ± 0.415
2.062AlaTyr: 2.062 ± 0.324
0.0AlaXaa: 0.0 ± 0.0
Cys
0.247CysAla: 0.247 ± 0.153
0.165CysCys: 0.165 ± 0.107
0.825CysAsp: 0.825 ± 0.254
0.577CysGlu: 0.577 ± 0.285
0.412CysPhe: 0.412 ± 0.171
0.99CysGly: 0.99 ± 0.316
0.165CysHis: 0.165 ± 0.115
0.577CysIle: 0.577 ± 0.187
0.495CysLys: 0.495 ± 0.231
1.155CysLeu: 1.155 ± 0.262
0.165CysMet: 0.165 ± 0.097
0.165CysAsn: 0.165 ± 0.12
0.742CysPro: 0.742 ± 0.283
0.0CysGln: 0.0 ± 0.0
0.907CysArg: 0.907 ± 0.272
0.412CysSer: 0.412 ± 0.219
0.66CysThr: 0.66 ± 0.266
0.412CysVal: 0.412 ± 0.346
0.165CysTrp: 0.165 ± 0.13
0.247CysTyr: 0.247 ± 0.152
0.0CysXaa: 0.0 ± 0.0
Asp
3.464AspAla: 3.464 ± 0.706
1.155AspCys: 1.155 ± 0.357
2.31AspAsp: 2.31 ± 0.391
4.949AspGlu: 4.949 ± 0.564
2.227AspPhe: 2.227 ± 0.473
3.629AspGly: 3.629 ± 1.114
1.32AspHis: 1.32 ± 0.27
4.372AspIle: 4.372 ± 0.586
5.197AspLys: 5.197 ± 0.637
7.836AspLeu: 7.836 ± 2.373
1.32AspMet: 1.32 ± 0.207
2.722AspAsn: 2.722 ± 0.503
3.052AspPro: 3.052 ± 0.417
1.65AspGln: 1.65 ± 0.392
2.97AspArg: 2.97 ± 0.389
3.382AspSer: 3.382 ± 0.719
3.959AspThr: 3.959 ± 0.582
4.289AspVal: 4.289 ± 0.756
0.907AspTrp: 0.907 ± 0.344
2.145AspTyr: 2.145 ± 0.461
0.0AspXaa: 0.0 ± 0.0
Glu
5.939GluAla: 5.939 ± 0.71
0.33GluCys: 0.33 ± 0.152
4.537GluAsp: 4.537 ± 0.718
6.599GluGlu: 6.599 ± 0.987
2.31GluPhe: 2.31 ± 0.434
5.114GluGly: 5.114 ± 0.599
1.98GluHis: 1.98 ± 0.453
4.454GluIle: 4.454 ± 0.535
4.784GluLys: 4.784 ± 1.102
7.011GluLeu: 7.011 ± 0.968
1.65GluMet: 1.65 ± 0.648
3.217GluAsn: 3.217 ± 0.439
1.897GluPro: 1.897 ± 0.469
5.527GluGln: 5.527 ± 1.911
5.362GluArg: 5.362 ± 0.81
3.712GluSer: 3.712 ± 0.723
3.217GluThr: 3.217 ± 0.46
5.197GluVal: 5.197 ± 0.84
0.742GluTrp: 0.742 ± 0.189
2.805GluTyr: 2.805 ± 0.393
0.0GluXaa: 0.0 ± 0.0
Phe
2.062PheAla: 2.062 ± 0.462
0.495PheCys: 0.495 ± 0.201
2.557PheAsp: 2.557 ± 0.503
3.3PheGlu: 3.3 ± 0.495
1.237PhePhe: 1.237 ± 0.383
2.805PheGly: 2.805 ± 0.589
0.907PheHis: 0.907 ± 0.278
2.062PheIle: 2.062 ± 0.422
3.959PheLys: 3.959 ± 0.521
3.135PheLeu: 3.135 ± 0.423
0.495PheMet: 0.495 ± 0.155
1.897PheAsn: 1.897 ± 0.285
1.155PhePro: 1.155 ± 0.305
1.32PheGln: 1.32 ± 0.323
1.402PheArg: 1.402 ± 0.291
2.392PheSer: 2.392 ± 0.596
2.392PheThr: 2.392 ± 0.369
2.31PheVal: 2.31 ± 0.489
0.495PheTrp: 0.495 ± 0.196
1.237PheTyr: 1.237 ± 0.249
0.0PheXaa: 0.0 ± 0.0
Gly
5.114GlyAla: 5.114 ± 0.724
1.155GlyCys: 1.155 ± 0.406
3.464GlyAsp: 3.464 ± 0.802
4.042GlyGlu: 4.042 ± 0.566
2.475GlyPhe: 2.475 ± 0.419
3.217GlyGly: 3.217 ± 0.716
0.825GlyHis: 0.825 ± 0.206
3.794GlyIle: 3.794 ± 0.647
3.712GlyLys: 3.712 ± 0.615
6.022GlyLeu: 6.022 ± 0.607
1.732GlyMet: 1.732 ± 0.303
2.145GlyAsn: 2.145 ± 0.727
0.742GlyPro: 0.742 ± 0.214
1.072GlyGln: 1.072 ± 0.365
4.042GlyArg: 4.042 ± 0.99
3.382GlySer: 3.382 ± 0.439
2.722GlyThr: 2.722 ± 0.426
4.702GlyVal: 4.702 ± 0.57
0.99GlyTrp: 0.99 ± 0.207
2.227GlyTyr: 2.227 ± 0.387
0.0GlyXaa: 0.0 ± 0.0
His
0.99HisAla: 0.99 ± 0.211
0.577HisCys: 0.577 ± 0.214
1.072HisAsp: 1.072 ± 0.333
0.577HisGlu: 0.577 ± 0.195
1.155HisPhe: 1.155 ± 0.319
1.32HisGly: 1.32 ± 0.355
0.825HisHis: 0.825 ± 0.224
0.99HisIle: 0.99 ± 0.284
1.65HisLys: 1.65 ± 0.387
1.98HisLeu: 1.98 ± 0.33
0.495HisMet: 0.495 ± 0.169
0.825HisAsn: 0.825 ± 0.232
1.567HisPro: 1.567 ± 0.372
1.567HisGln: 1.567 ± 0.344
1.485HisArg: 1.485 ± 0.335
1.65HisSer: 1.65 ± 0.375
1.485HisThr: 1.485 ± 0.469
1.32HisVal: 1.32 ± 0.206
0.412HisTrp: 0.412 ± 0.186
0.825HisTyr: 0.825 ± 0.264
0.0HisXaa: 0.0 ± 0.0
Ile
4.124IleAla: 4.124 ± 0.658
0.33IleCys: 0.33 ± 0.152
5.939IleAsp: 5.939 ± 2.334
4.207IleGlu: 4.207 ± 0.803
1.567IlePhe: 1.567 ± 0.33
3.464IleGly: 3.464 ± 0.49
1.072IleHis: 1.072 ± 0.266
3.712IleIle: 3.712 ± 0.625
5.279IleLys: 5.279 ± 0.756
4.042IleLeu: 4.042 ± 0.65
0.907IleMet: 0.907 ± 0.287
2.722IleAsn: 2.722 ± 0.426
2.97IlePro: 2.97 ± 0.461
2.062IleGln: 2.062 ± 0.33
3.3IleArg: 3.3 ± 0.641
4.042IleSer: 4.042 ± 0.626
3.382IleThr: 3.382 ± 0.531
4.372IleVal: 4.372 ± 0.795
0.33IleTrp: 0.33 ± 0.169
1.402IleTyr: 1.402 ± 0.366
0.0IleXaa: 0.0 ± 0.0
Lys
6.269LysAla: 6.269 ± 0.911
0.247LysCys: 0.247 ± 0.132
6.187LysAsp: 6.187 ± 0.959
7.506LysGlu: 7.506 ± 1.513
1.815LysPhe: 1.815 ± 0.377
5.527LysGly: 5.527 ± 0.527
2.475LysHis: 2.475 ± 0.493
3.877LysIle: 3.877 ± 0.639
5.774LysLys: 5.774 ± 0.839
9.486LysLeu: 9.486 ± 1.678
2.31LysMet: 2.31 ± 0.901
2.97LysAsn: 2.97 ± 0.482
2.722LysPro: 2.722 ± 0.504
3.382LysGln: 3.382 ± 0.589
4.619LysArg: 4.619 ± 0.631
4.784LysSer: 4.784 ± 0.567
4.207LysThr: 4.207 ± 0.482
4.537LysVal: 4.537 ± 0.616
1.237LysTrp: 1.237 ± 0.29
1.65LysTyr: 1.65 ± 0.373
0.0LysXaa: 0.0 ± 0.0
Leu
7.919LeuAla: 7.919 ± 1.004
0.742LeuCys: 0.742 ± 0.324
5.857LeuAsp: 5.857 ± 1.092
8.249LeuGlu: 8.249 ± 1.721
3.3LeuPhe: 3.3 ± 0.702
4.207LeuGly: 4.207 ± 0.496
1.485LeuHis: 1.485 ± 0.335
4.867LeuIle: 4.867 ± 0.775
8.331LeuLys: 8.331 ± 1.261
6.682LeuLeu: 6.682 ± 0.893
1.567LeuMet: 1.567 ± 0.341
4.289LeuAsn: 4.289 ± 0.449
3.464LeuPro: 3.464 ± 0.61
4.207LeuGln: 4.207 ± 0.65
4.702LeuArg: 4.702 ± 0.583
10.641LeuSer: 10.641 ± 1.781
5.114LeuThr: 5.114 ± 1.023
4.372LeuVal: 4.372 ± 0.562
1.32LeuTrp: 1.32 ± 0.409
2.475LeuTyr: 2.475 ± 0.419
0.0LeuXaa: 0.0 ± 0.0
Met
2.31MetAla: 2.31 ± 0.719
0.412MetCys: 0.412 ± 0.151
1.815MetAsp: 1.815 ± 0.539
1.98MetGlu: 1.98 ± 0.602
0.66MetPhe: 0.66 ± 0.238
0.99MetGly: 0.99 ± 0.258
0.825MetHis: 0.825 ± 0.311
1.072MetIle: 1.072 ± 0.319
1.732MetLys: 1.732 ± 0.322
0.907MetLeu: 0.907 ± 0.357
0.33MetMet: 0.33 ± 0.122
1.732MetAsn: 1.732 ± 0.748
0.825MetPro: 0.825 ± 0.223
0.99MetGln: 0.99 ± 0.23
0.66MetArg: 0.66 ± 0.192
1.65MetSer: 1.65 ± 0.368
0.99MetThr: 0.99 ± 0.271
0.907MetVal: 0.907 ± 0.279
0.33MetTrp: 0.33 ± 0.207
0.742MetTyr: 0.742 ± 0.249
0.0MetXaa: 0.0 ± 0.0
Asn
3.629AsnAla: 3.629 ± 0.986
0.247AsnCys: 0.247 ± 0.165
2.062AsnAsp: 2.062 ± 0.5
2.145AsnGlu: 2.145 ± 0.454
1.567AsnPhe: 1.567 ± 0.261
1.485AsnGly: 1.485 ± 0.356
1.072AsnHis: 1.072 ± 0.25
3.217AsnIle: 3.217 ± 0.733
3.135AsnLys: 3.135 ± 0.597
2.722AsnLeu: 2.722 ± 0.391
0.99AsnMet: 0.99 ± 0.312
2.557AsnAsn: 2.557 ± 0.726
2.557AsnPro: 2.557 ± 0.515
1.897AsnGln: 1.897 ± 0.389
2.64AsnArg: 2.64 ± 0.481
2.557AsnSer: 2.557 ± 0.328
3.382AsnThr: 3.382 ± 0.575
1.815AsnVal: 1.815 ± 0.475
0.33AsnTrp: 0.33 ± 0.211
1.237AsnTyr: 1.237 ± 0.379
0.0AsnXaa: 0.0 ± 0.0
Pro
1.98ProAla: 1.98 ± 0.29
0.165ProCys: 0.165 ± 0.114
2.392ProAsp: 2.392 ± 0.592
2.227ProGlu: 2.227 ± 0.425
1.485ProPhe: 1.485 ± 0.447
1.072ProGly: 1.072 ± 0.319
1.237ProHis: 1.237 ± 0.597
1.65ProIle: 1.65 ± 0.359
2.227ProLys: 2.227 ± 0.392
5.444ProLeu: 5.444 ± 0.672
0.825ProMet: 0.825 ± 0.253
1.402ProAsn: 1.402 ± 0.314
2.475ProPro: 2.475 ± 0.541
1.567ProGln: 1.567 ± 0.222
2.145ProArg: 2.145 ± 0.337
3.547ProSer: 3.547 ± 0.474
1.567ProThr: 1.567 ± 0.357
1.732ProVal: 1.732 ± 0.254
0.577ProTrp: 0.577 ± 0.227
1.402ProTyr: 1.402 ± 0.341
0.0ProXaa: 0.0 ± 0.0
Gln
2.97GlnAla: 2.97 ± 0.504
0.082GlnCys: 0.082 ± 0.087
2.392GlnAsp: 2.392 ± 0.505
3.712GlnGlu: 3.712 ± 0.542
1.567GlnPhe: 1.567 ± 0.311
1.815GlnGly: 1.815 ± 0.383
0.66GlnHis: 0.66 ± 0.181
3.959GlnIle: 3.959 ± 1.81
4.454GlnLys: 4.454 ± 0.838
3.464GlnLeu: 3.464 ± 0.439
0.825GlnMet: 0.825 ± 0.318
1.237GlnAsn: 1.237 ± 0.344
0.99GlnPro: 0.99 ± 0.255
1.732GlnGln: 1.732 ± 0.51
2.805GlnArg: 2.805 ± 0.567
2.475GlnSer: 2.475 ± 0.383
2.97GlnThr: 2.97 ± 1.025
1.155GlnVal: 1.155 ± 0.357
0.577GlnTrp: 0.577 ± 0.216
1.402GlnTyr: 1.402 ± 0.409
0.0GlnXaa: 0.0 ± 0.0
Arg
2.805ArgAla: 2.805 ± 0.472
0.495ArgCys: 0.495 ± 0.159
3.382ArgAsp: 3.382 ± 0.893
4.619ArgGlu: 4.619 ± 0.704
2.97ArgPhe: 2.97 ± 0.442
3.135ArgGly: 3.135 ± 0.548
0.742ArgHis: 0.742 ± 0.217
3.959ArgIle: 3.959 ± 0.561
3.712ArgLys: 3.712 ± 0.87
5.857ArgLeu: 5.857 ± 0.63
1.567ArgMet: 1.567 ± 0.356
1.155ArgAsn: 1.155 ± 0.311
1.485ArgPro: 1.485 ± 0.393
2.31ArgGln: 2.31 ± 0.533
3.877ArgArg: 3.877 ± 0.892
4.537ArgSer: 4.537 ± 0.75
2.805ArgThr: 2.805 ± 0.605
3.629ArgVal: 3.629 ± 0.378
0.907ArgTrp: 0.907 ± 0.279
3.135ArgTyr: 3.135 ± 0.43
0.0ArgXaa: 0.0 ± 0.0
Ser
4.619SerAla: 4.619 ± 0.818
0.66SerCys: 0.66 ± 0.221
5.527SerAsp: 5.527 ± 0.734
6.104SerGlu: 6.104 ± 0.65
3.959SerPhe: 3.959 ± 0.561
3.547SerGly: 3.547 ± 0.772
1.897SerHis: 1.897 ± 0.4
3.959SerIle: 3.959 ± 0.655
7.506SerLys: 7.506 ± 1.25
7.424SerLeu: 7.424 ± 0.89
1.485SerMet: 1.485 ± 0.409
2.392SerAsn: 2.392 ± 0.414
2.145SerPro: 2.145 ± 0.435
2.227SerGln: 2.227 ± 0.38
2.887SerArg: 2.887 ± 0.476
6.022SerSer: 6.022 ± 0.754
4.289SerThr: 4.289 ± 0.618
4.454SerVal: 4.454 ± 0.663
0.825SerTrp: 0.825 ± 0.227
1.65SerTyr: 1.65 ± 0.372
0.0SerXaa: 0.0 ± 0.0
Thr
3.382ThrAla: 3.382 ± 0.596
0.165ThrCys: 0.165 ± 0.118
2.392ThrAsp: 2.392 ± 0.442
4.042ThrGlu: 4.042 ± 0.845
2.31ThrPhe: 2.31 ± 0.459
2.722ThrGly: 2.722 ± 0.483
0.825ThrHis: 0.825 ± 0.273
3.3ThrIle: 3.3 ± 0.657
5.774ThrLys: 5.774 ± 0.749
4.124ThrLeu: 4.124 ± 0.53
0.66ThrMet: 0.66 ± 0.178
1.815ThrAsn: 1.815 ± 0.315
3.464ThrPro: 3.464 ± 0.456
4.372ThrGln: 4.372 ± 1.57
2.805ThrArg: 2.805 ± 0.396
4.042ThrSer: 4.042 ± 0.448
2.227ThrThr: 2.227 ± 0.474
3.382ThrVal: 3.382 ± 0.456
0.33ThrTrp: 0.33 ± 0.201
1.815ThrTyr: 1.815 ± 0.359
0.0ThrXaa: 0.0 ± 0.0
Val
3.3ValAla: 3.3 ± 0.528
0.577ValCys: 0.577 ± 0.195
3.712ValAsp: 3.712 ± 0.521
4.784ValGlu: 4.784 ± 0.582
2.227ValPhe: 2.227 ± 0.474
5.114ValGly: 5.114 ± 1.158
0.825ValHis: 0.825 ± 0.238
2.805ValIle: 2.805 ± 0.427
4.784ValLys: 4.784 ± 0.643
6.104ValLeu: 6.104 ± 0.782
1.32ValMet: 1.32 ± 0.406
3.382ValAsn: 3.382 ± 0.898
1.567ValPro: 1.567 ± 0.27
1.815ValGln: 1.815 ± 0.37
4.124ValArg: 4.124 ± 0.976
5.279ValSer: 5.279 ± 0.83
1.98ValThr: 1.98 ± 0.369
3.629ValVal: 3.629 ± 0.605
0.742ValTrp: 0.742 ± 0.268
1.815ValTyr: 1.815 ± 0.359
0.0ValXaa: 0.0 ± 0.0
Trp
1.402TrpAla: 1.402 ± 0.234
0.082TrpCys: 0.082 ± 0.077
0.907TrpAsp: 0.907 ± 0.243
0.742TrpGlu: 0.742 ± 0.273
0.825TrpPhe: 0.825 ± 0.252
0.66TrpGly: 0.66 ± 0.219
0.495TrpHis: 0.495 ± 0.163
1.237TrpIle: 1.237 ± 0.283
0.99TrpLys: 0.99 ± 0.303
1.237TrpLeu: 1.237 ± 0.425
0.495TrpMet: 0.495 ± 0.22
0.577TrpAsn: 0.577 ± 0.212
0.0TrpPro: 0.0 ± 0.0
0.165TrpGln: 0.165 ± 0.125
0.412TrpArg: 0.412 ± 0.169
1.072TrpSer: 1.072 ± 0.235
0.412TrpThr: 0.412 ± 0.185
0.825TrpVal: 0.825 ± 0.253
0.33TrpTrp: 0.33 ± 0.143
0.495TrpTyr: 0.495 ± 0.189
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.722TyrAla: 2.722 ± 0.466
0.33TyrCys: 0.33 ± 0.15
1.732TyrAsp: 1.732 ± 0.333
2.145TyrGlu: 2.145 ± 0.448
1.237TyrPhe: 1.237 ± 0.283
2.145TyrGly: 2.145 ± 0.36
0.825TyrHis: 0.825 ± 0.241
2.062TyrIle: 2.062 ± 0.404
2.392TyrLys: 2.392 ± 0.516
2.722TyrLeu: 2.722 ± 0.511
0.907TyrMet: 0.907 ± 0.351
1.155TyrAsn: 1.155 ± 0.421
1.237TyrPro: 1.237 ± 0.323
0.99TyrGln: 0.99 ± 0.224
2.145TyrArg: 2.145 ± 0.382
2.227TyrSer: 2.227 ± 0.524
1.732TyrThr: 1.732 ± 0.4
1.402TyrVal: 1.402 ± 0.346
0.66TyrTrp: 0.66 ± 0.234
1.237TyrTyr: 1.237 ± 0.386
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 40 proteins (12124 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski