Amino acid dipepetide frequency for Saimiriine herpesvirus 2 (SaHV-2) (Herpesvirus saimiri)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.472AlaAla: 3.472 ± 0.388
1.43AlaCys: 1.43 ± 0.211
1.838AlaAsp: 1.838 ± 0.214
2.713AlaGlu: 2.713 ± 0.8
2.159AlaPhe: 2.159 ± 0.217
1.78AlaGly: 1.78 ± 0.259
1.4AlaHis: 1.4 ± 0.234
3.764AlaIle: 3.764 ± 0.357
3.063AlaLys: 3.063 ± 0.316
5.222AlaLeu: 5.222 ± 0.477
1.634AlaMet: 1.634 ± 0.199
2.538AlaAsn: 2.538 ± 0.223
2.743AlaPro: 2.743 ± 0.263
2.188AlaGln: 2.188 ± 0.242
1.43AlaArg: 1.43 ± 0.178
4.493AlaSer: 4.493 ± 0.313
3.18AlaThr: 3.18 ± 0.338
3.501AlaVal: 3.501 ± 0.406
0.671AlaTrp: 0.671 ± 0.139
1.634AlaTyr: 1.634 ± 0.212
0.0AlaXaa: 0.0 ± 0.0
Cys
1.196CysAla: 1.196 ± 0.249
0.759CysCys: 0.759 ± 0.151
1.109CysAsp: 1.109 ± 0.196
1.4CysGlu: 1.4 ± 0.248
1.196CysPhe: 1.196 ± 0.172
1.284CysGly: 1.284 ± 0.248
0.584CysHis: 0.584 ± 0.122
1.867CysIle: 1.867 ± 0.231
1.605CysLys: 1.605 ± 0.232
3.443CysLeu: 3.443 ± 0.441
0.554CysMet: 0.554 ± 0.114
1.605CysAsn: 1.605 ± 0.288
1.43CysPro: 1.43 ± 0.225
1.284CysGln: 1.284 ± 0.266
0.671CysArg: 0.671 ± 0.152
2.071CysSer: 2.071 ± 0.3
1.751CysThr: 1.751 ± 0.26
1.984CysVal: 1.984 ± 0.227
0.292CysTrp: 0.292 ± 0.084
1.196CysTyr: 1.196 ± 0.216
0.0CysXaa: 0.0 ± 0.0
Asp
2.509AspAla: 2.509 ± 0.285
1.167AspCys: 1.167 ± 0.17
2.217AspAsp: 2.217 ± 0.351
3.589AspGlu: 3.589 ± 1.399
2.188AspPhe: 2.188 ± 0.26
1.517AspGly: 1.517 ± 0.239
0.642AspHis: 0.642 ± 0.143
3.968AspIle: 3.968 ± 0.379
2.772AspLys: 2.772 ± 0.237
4.785AspLeu: 4.785 ± 0.322
1.225AspMet: 1.225 ± 0.194
1.926AspAsn: 1.926 ± 0.279
2.217AspPro: 2.217 ± 0.263
1.313AspGln: 1.313 ± 0.172
1.663AspArg: 1.663 ± 0.186
3.705AspSer: 3.705 ± 0.396
3.414AspThr: 3.414 ± 0.276
2.743AspVal: 2.743 ± 0.301
0.467AspTrp: 0.467 ± 0.111
1.955AspTyr: 1.955 ± 0.218
0.0AspXaa: 0.0 ± 0.0
Glu
3.822GluAla: 3.822 ± 0.867
1.05GluCys: 1.05 ± 0.22
4.814GluAsp: 4.814 ± 1.46
7.615GluGlu: 7.615 ± 2.953
2.013GluPhe: 2.013 ± 0.235
2.83GluGly: 2.83 ± 1.618
1.575GluHis: 1.575 ± 0.16
4.23GluIle: 4.23 ± 0.4
3.793GluLys: 3.793 ± 0.305
4.522GluLeu: 4.522 ± 0.434
1.167GluMet: 1.167 ± 0.18
4.23GluAsn: 4.23 ± 0.414
1.78GluPro: 1.78 ± 0.203
1.488GluGln: 1.488 ± 0.144
1.255GluArg: 1.255 ± 0.244
3.793GluSer: 3.793 ± 0.318
3.91GluThr: 3.91 ± 0.289
2.947GluVal: 2.947 ± 0.24
0.35GluTrp: 0.35 ± 0.077
1.721GluTyr: 1.721 ± 0.263
0.0GluXaa: 0.0 ± 0.0
Phe
1.721PheAla: 1.721 ± 0.263
1.43PheCys: 1.43 ± 0.219
2.13PheAsp: 2.13 ± 0.232
2.071PheGlu: 2.071 ± 0.262
2.305PhePhe: 2.305 ± 0.253
1.809PheGly: 1.809 ± 0.237
0.934PheHis: 0.934 ± 0.16
4.114PheIle: 4.114 ± 0.362
3.822PheLys: 3.822 ± 0.319
5.923PheLeu: 5.923 ± 0.378
1.109PheMet: 1.109 ± 0.212
2.247PheAsn: 2.247 ± 0.267
2.217PhePro: 2.217 ± 0.283
1.955PheGln: 1.955 ± 0.258
1.575PheArg: 1.575 ± 0.188
4.289PheSer: 4.289 ± 0.353
2.597PheThr: 2.597 ± 0.271
2.859PheVal: 2.859 ± 0.341
0.525PheTrp: 0.525 ± 0.126
2.392PheTyr: 2.392 ± 0.293
0.0PheXaa: 0.0 ± 0.0
Gly
2.101GlyAla: 2.101 ± 0.252
0.788GlyCys: 0.788 ± 0.159
1.459GlyAsp: 1.459 ± 0.178
3.268GlyGlu: 3.268 ± 1.664
1.955GlyPhe: 1.955 ± 0.283
1.896GlyGly: 1.896 ± 0.592
1.021GlyHis: 1.021 ± 0.185
2.509GlyIle: 2.509 ± 0.241
2.509GlyLys: 2.509 ± 0.279
3.559GlyLeu: 3.559 ± 0.292
0.846GlyMet: 0.846 ± 0.197
1.984GlyAsn: 1.984 ± 0.269
2.392GlyPro: 2.392 ± 0.537
1.605GlyGln: 1.605 ± 0.204
1.634GlyArg: 1.634 ± 0.278
2.801GlySer: 2.801 ± 0.276
2.801GlyThr: 2.801 ± 0.271
2.276GlyVal: 2.276 ± 0.336
0.263GlyTrp: 0.263 ± 0.081
1.342GlyTyr: 1.342 ± 0.25
0.0GlyXaa: 0.0 ± 0.0
His
0.904HisAla: 0.904 ± 0.163
0.7HisCys: 0.7 ± 0.139
0.846HisAsp: 0.846 ± 0.132
1.167HisGlu: 1.167 ± 0.166
1.371HisPhe: 1.371 ± 0.194
1.255HisGly: 1.255 ± 0.142
0.7HisHis: 0.7 ± 0.137
2.976HisIle: 2.976 ± 0.303
2.13HisLys: 2.13 ± 0.222
3.18HisLeu: 3.18 ± 0.32
0.613HisMet: 0.613 ± 0.121
1.08HisAsn: 1.08 ± 0.215
1.342HisPro: 1.342 ± 0.201
1.021HisGln: 1.021 ± 0.164
0.729HisArg: 0.729 ± 0.168
1.78HisSer: 1.78 ± 0.223
1.984HisThr: 1.984 ± 0.158
2.188HisVal: 2.188 ± 0.287
0.204HisTrp: 0.204 ± 0.088
0.759HisTyr: 0.759 ± 0.148
0.0HisXaa: 0.0 ± 0.0
Ile
3.443IleAla: 3.443 ± 0.264
2.276IleCys: 2.276 ± 0.264
3.18IleAsp: 3.18 ± 0.386
3.793IleGlu: 3.793 ± 0.386
3.472IlePhe: 3.472 ± 0.399
2.859IleGly: 2.859 ± 0.314
2.013IleHis: 2.013 ± 0.186
5.106IleIle: 5.106 ± 0.44
4.726IleLys: 4.726 ± 0.452
7.907IleLeu: 7.907 ± 0.522
1.459IleMet: 1.459 ± 0.173
4.26IleAsn: 4.26 ± 0.32
3.705IlePro: 3.705 ± 0.429
2.83IleGln: 2.83 ± 0.408
2.13IleArg: 2.13 ± 0.241
6.389IleSer: 6.389 ± 0.456
4.61IleThr: 4.61 ± 0.389
4.26IleVal: 4.26 ± 0.379
0.671IleTrp: 0.671 ± 0.154
2.976IleTyr: 2.976 ± 0.35
0.0IleXaa: 0.0 ± 0.0
Lys
3.151LysAla: 3.151 ± 0.32
1.809LysCys: 1.809 ± 0.265
3.355LysAsp: 3.355 ± 0.443
3.443LysGlu: 3.443 ± 0.28
3.093LysPhe: 3.093 ± 0.319
1.838LysGly: 1.838 ± 0.258
2.13LysHis: 2.13 ± 0.226
4.902LysIle: 4.902 ± 0.342
5.077LysLys: 5.077 ± 0.445
7.206LysLeu: 7.206 ± 0.54
1.43LysMet: 1.43 ± 0.212
4.756LysAsn: 4.756 ± 0.317
3.384LysPro: 3.384 ± 0.392
2.772LysGln: 2.772 ± 0.393
2.713LysArg: 2.713 ± 0.307
5.193LysSer: 5.193 ± 0.409
5.252LysThr: 5.252 ± 0.49
3.326LysVal: 3.326 ± 0.304
0.525LysTrp: 0.525 ± 0.119
2.451LysTyr: 2.451 ± 0.258
0.0LysXaa: 0.0 ± 0.0
Leu
5.543LeuAla: 5.543 ± 0.385
2.947LeuCys: 2.947 ± 0.37
4.697LeuAsp: 4.697 ± 0.405
5.66LeuGlu: 5.66 ± 0.432
5.339LeuPhe: 5.339 ± 0.424
3.764LeuGly: 3.764 ± 0.36
2.859LeuHis: 2.859 ± 0.231
5.835LeuIle: 5.835 ± 0.455
7.411LeuLys: 7.411 ± 0.523
11.058LeuLeu: 11.058 ± 0.625
2.13LeuMet: 2.13 ± 0.253
6.535LeuAsn: 6.535 ± 0.533
5.602LeuPro: 5.602 ± 0.35
4.989LeuGln: 4.989 ± 0.437
3.384LeuArg: 3.384 ± 0.286
8.928LeuSer: 8.928 ± 0.707
6.389LeuThr: 6.389 ± 0.414
5.398LeuVal: 5.398 ± 0.404
1.138LeuTrp: 1.138 ± 0.178
3.705LeuTyr: 3.705 ± 0.272
0.0LeuXaa: 0.0 ± 0.0
Met
1.459MetAla: 1.459 ± 0.22
0.875MetCys: 0.875 ± 0.236
0.934MetAsp: 0.934 ± 0.181
1.138MetGlu: 1.138 ± 0.192
1.663MetPhe: 1.663 ± 0.218
0.7MetGly: 0.7 ± 0.171
0.554MetHis: 0.554 ± 0.123
0.934MetIle: 0.934 ± 0.165
0.904MetLys: 0.904 ± 0.172
3.151MetLeu: 3.151 ± 0.365
0.438MetMet: 0.438 ± 0.167
1.08MetAsn: 1.08 ± 0.151
1.138MetPro: 1.138 ± 0.278
0.992MetGln: 0.992 ± 0.17
0.7MetArg: 0.7 ± 0.161
1.809MetSer: 1.809 ± 0.208
1.605MetThr: 1.605 ± 0.221
0.992MetVal: 0.992 ± 0.2
0.263MetTrp: 0.263 ± 0.09
0.846MetTyr: 0.846 ± 0.169
0.0MetXaa: 0.0 ± 0.0
Asn
2.159AsnAla: 2.159 ± 0.235
1.488AsnCys: 1.488 ± 0.219
2.217AsnAsp: 2.217 ± 0.277
2.567AsnGlu: 2.567 ± 0.473
2.772AsnPhe: 2.772 ± 0.267
2.305AsnGly: 2.305 ± 0.328
1.196AsnHis: 1.196 ± 0.184
5.864AsnIle: 5.864 ± 0.483
3.968AsnLys: 3.968 ± 0.355
6.069AsnLeu: 6.069 ± 0.33
1.43AsnMet: 1.43 ± 0.223
3.443AsnAsn: 3.443 ± 0.271
1.955AsnPro: 1.955 ± 0.229
1.43AsnGln: 1.43 ± 0.268
1.225AsnArg: 1.225 ± 0.169
4.785AsnSer: 4.785 ± 0.387
3.88AsnThr: 3.88 ± 0.527
4.026AsnVal: 4.026 ± 0.284
0.671AsnTrp: 0.671 ± 0.139
2.042AsnTyr: 2.042 ± 0.264
0.0AsnXaa: 0.0 ± 0.0
Pro
1.838ProAla: 1.838 ± 0.228
1.488ProCys: 1.488 ± 0.209
1.867ProAsp: 1.867 ± 0.273
2.101ProGlu: 2.101 ± 0.246
2.042ProPhe: 2.042 ± 0.243
2.392ProGly: 2.392 ± 0.491
1.663ProHis: 1.663 ± 0.21
3.793ProIle: 3.793 ± 0.34
4.055ProLys: 4.055 ± 0.517
4.756ProLeu: 4.756 ± 0.401
1.109ProMet: 1.109 ± 0.162
2.247ProAsn: 2.247 ± 0.298
3.034ProPro: 3.034 ± 0.46
2.538ProGln: 2.538 ± 0.303
2.392ProArg: 2.392 ± 0.27
4.493ProSer: 4.493 ± 0.326
3.005ProThr: 3.005 ± 0.343
3.209ProVal: 3.209 ± 0.325
0.729ProTrp: 0.729 ± 0.159
1.955ProTyr: 1.955 ± 0.276
0.0ProXaa: 0.0 ± 0.0
Gln
2.159GlnAla: 2.159 ± 0.246
1.138GlnCys: 1.138 ± 0.2
2.042GlnAsp: 2.042 ± 0.253
1.984GlnGlu: 1.984 ± 0.272
1.751GlnPhe: 1.751 ± 0.256
1.692GlnGly: 1.692 ± 0.235
1.751GlnHis: 1.751 ± 0.283
2.83GlnIle: 2.83 ± 0.296
2.713GlnLys: 2.713 ± 0.426
3.559GlnLeu: 3.559 ± 0.329
0.759GlnMet: 0.759 ± 0.134
2.305GlnAsn: 2.305 ± 0.233
1.867GlnPro: 1.867 ± 0.331
1.663GlnGln: 1.663 ± 0.224
1.634GlnArg: 1.634 ± 0.234
2.83GlnSer: 2.83 ± 0.358
2.918GlnThr: 2.918 ± 0.299
1.43GlnVal: 1.43 ± 0.18
0.554GlnTrp: 0.554 ± 0.123
1.4GlnTyr: 1.4 ± 0.273
0.0GlnXaa: 0.0 ± 0.0
Arg
2.247ArgAla: 2.247 ± 0.284
0.846ArgCys: 0.846 ± 0.158
1.634ArgAsp: 1.634 ± 0.211
2.217ArgGlu: 2.217 ± 0.266
1.109ArgPhe: 1.109 ± 0.207
1.517ArgGly: 1.517 ± 0.23
1.255ArgHis: 1.255 ± 0.214
1.78ArgIle: 1.78 ± 0.222
2.451ArgLys: 2.451 ± 0.335
3.093ArgLeu: 3.093 ± 0.321
0.817ArgMet: 0.817 ± 0.149
1.692ArgAsn: 1.692 ± 0.214
1.955ArgPro: 1.955 ± 0.23
1.138ArgGln: 1.138 ± 0.188
2.042ArgArg: 2.042 ± 0.409
2.013ArgSer: 2.013 ± 0.227
1.867ArgThr: 1.867 ± 0.255
1.926ArgVal: 1.926 ± 0.21
0.263ArgTrp: 0.263 ± 0.094
1.284ArgTyr: 1.284 ± 0.229
0.0ArgXaa: 0.0 ± 0.0
Ser
4.289SerAla: 4.289 ± 0.379
2.159SerCys: 2.159 ± 0.29
3.91SerAsp: 3.91 ± 0.346
4.581SerGlu: 4.581 ± 0.376
4.055SerPhe: 4.055 ± 0.378
2.859SerGly: 2.859 ± 0.348
2.13SerHis: 2.13 ± 0.237
6.098SerIle: 6.098 ± 0.434
5.485SerLys: 5.485 ± 0.373
8.373SerLeu: 8.373 ± 0.484
1.546SerMet: 1.546 ± 0.214
4.581SerAsn: 4.581 ± 0.461
4.114SerPro: 4.114 ± 0.397
3.676SerGln: 3.676 ± 0.267
3.005SerArg: 3.005 ± 0.246
7.965SerSer: 7.965 ± 0.542
6.36SerThr: 6.36 ± 0.462
5.573SerVal: 5.573 ± 0.444
0.904SerTrp: 0.904 ± 0.164
2.567SerTyr: 2.567 ± 0.246
0.0SerXaa: 0.0 ± 0.0
Thr
3.414ThrAla: 3.414 ± 0.364
1.896ThrCys: 1.896 ± 0.243
3.326ThrAsp: 3.326 ± 0.344
4.289ThrGlu: 4.289 ± 0.352
3.268ThrPhe: 3.268 ± 0.339
2.422ThrGly: 2.422 ± 0.304
1.575ThrHis: 1.575 ± 0.299
4.26ThrIle: 4.26 ± 0.371
3.91ThrLys: 3.91 ± 0.334
6.71ThrLeu: 6.71 ± 0.443
1.284ThrMet: 1.284 ± 0.179
2.859ThrAsn: 2.859 ± 0.285
3.384ThrPro: 3.384 ± 0.292
2.48ThrGln: 2.48 ± 0.263
1.605ThrArg: 1.605 ± 0.225
7.236ThrSer: 7.236 ± 0.548
4.639ThrThr: 4.639 ± 0.539
4.785ThrVal: 4.785 ± 0.401
0.788ThrTrp: 0.788 ± 0.155
2.976ThrTyr: 2.976 ± 0.392
0.0ThrXaa: 0.0 ± 0.0
Val
2.888ValAla: 2.888 ± 0.323
1.663ValCys: 1.663 ± 0.216
2.247ValAsp: 2.247 ± 0.258
2.976ValGlu: 2.976 ± 0.298
3.851ValPhe: 3.851 ± 0.323
2.217ValGly: 2.217 ± 0.32
1.838ValHis: 1.838 ± 0.255
3.647ValIle: 3.647 ± 0.284
4.055ValLys: 4.055 ± 0.332
6.156ValLeu: 6.156 ± 0.509
1.342ValMet: 1.342 ± 0.173
3.209ValAsn: 3.209 ± 0.329
4.143ValPro: 4.143 ± 0.334
2.159ValGln: 2.159 ± 0.268
1.605ValArg: 1.605 ± 0.276
5.806ValSer: 5.806 ± 0.514
3.414ValThr: 3.414 ± 0.355
3.239ValVal: 3.239 ± 0.434
0.584ValTrp: 0.584 ± 0.152
2.684ValTyr: 2.684 ± 0.3
0.0ValXaa: 0.0 ± 0.0
Trp
0.817TrpAla: 0.817 ± 0.153
0.292TrpCys: 0.292 ± 0.112
0.408TrpAsp: 0.408 ± 0.124
0.496TrpGlu: 0.496 ± 0.127
0.467TrpPhe: 0.467 ± 0.108
0.467TrpGly: 0.467 ± 0.104
0.35TrpHis: 0.35 ± 0.087
0.817TrpIle: 0.817 ± 0.142
0.613TrpLys: 0.613 ± 0.147
0.846TrpLeu: 0.846 ± 0.161
0.146TrpMet: 0.146 ± 0.069
0.584TrpAsn: 0.584 ± 0.116
0.554TrpPro: 0.554 ± 0.12
0.525TrpGln: 0.525 ± 0.12
0.321TrpArg: 0.321 ± 0.104
0.759TrpSer: 0.759 ± 0.145
0.992TrpThr: 0.992 ± 0.159
0.438TrpVal: 0.438 ± 0.121
0.0TrpTrp: 0.0 ± 0.0
0.554TrpTyr: 0.554 ± 0.126
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.721TyrAla: 1.721 ± 0.307
1.08TyrCys: 1.08 ± 0.188
1.751TyrAsp: 1.751 ± 0.212
1.838TyrGlu: 1.838 ± 0.23
1.984TyrPhe: 1.984 ± 0.266
1.605TyrGly: 1.605 ± 0.199
0.759TyrHis: 0.759 ± 0.184
2.772TyrIle: 2.772 ± 0.343
2.743TyrLys: 2.743 ± 0.282
3.793TyrLeu: 3.793 ± 0.392
1.109TyrMet: 1.109 ± 0.22
2.334TyrAsn: 2.334 ± 0.254
1.751TyrPro: 1.751 ± 0.185
0.934TyrGln: 0.934 ± 0.182
1.43TyrArg: 1.43 ± 0.173
3.093TyrSer: 3.093 ± 0.33
2.538TyrThr: 2.538 ± 0.294
2.626TyrVal: 2.626 ± 0.323
0.584TyrTrp: 0.584 ± 0.125
1.4TyrTyr: 1.4 ± 0.175
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 79 proteins (34276 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski