Amino acid dipepetide frequency for Hubei tombus-like virus 26

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.326AlaAla: 1.326 ± 0.752
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
1.326AlaGlu: 1.326 ± 1.068
3.979AlaPhe: 3.979 ± 0.436
2.653AlaGly: 2.653 ± 1.504
3.979AlaHis: 3.979 ± 1.384
1.326AlaIle: 1.326 ± 1.068
0.0AlaLys: 0.0 ± 0.0
3.979AlaLeu: 3.979 ± 3.204
1.326AlaMet: 1.326 ± 1.068
1.326AlaAsn: 1.326 ± 0.752
3.979AlaPro: 3.979 ± 1.384
1.326AlaGln: 1.326 ± 0.752
3.979AlaArg: 3.979 ± 0.436
9.284AlaSer: 9.284 ± 3.836
3.979AlaThr: 3.979 ± 0.436
1.326AlaVal: 1.326 ± 0.752
0.0AlaTrp: 0.0 ± 0.0
3.979AlaTyr: 3.979 ± 0.436
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.326CysPhe: 1.326 ± 0.752
0.0CysGly: 0.0 ± 0.0
1.326CysHis: 1.326 ± 0.752
3.979CysIle: 3.979 ± 2.255
1.326CysLys: 1.326 ± 0.752
1.326CysLeu: 1.326 ± 1.068
0.0CysMet: 0.0 ± 0.0
1.326CysAsn: 1.326 ± 1.068
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.653CysArg: 2.653 ± 0.316
0.0CysSer: 0.0 ± 0.0
1.326CysThr: 1.326 ± 1.068
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.653AspAla: 2.653 ± 1.504
0.0AspCys: 0.0 ± 0.0
1.326AspAsp: 1.326 ± 0.752
2.653AspGlu: 2.653 ± 0.316
5.305AspPhe: 5.305 ± 4.272
0.0AspGly: 0.0 ± 0.0
2.653AspHis: 2.653 ± 0.316
1.326AspIle: 1.326 ± 0.752
0.0AspLys: 0.0 ± 0.0
2.653AspLeu: 2.653 ± 1.504
0.0AspMet: 0.0 ± 0.0
1.326AspAsn: 1.326 ± 0.752
2.653AspPro: 2.653 ± 1.504
1.326AspGln: 1.326 ± 0.752
1.326AspArg: 1.326 ± 0.752
3.979AspSer: 3.979 ± 0.436
1.326AspThr: 1.326 ± 1.068
1.326AspVal: 1.326 ± 0.752
0.0AspTrp: 0.0 ± 0.0
1.326AspTyr: 1.326 ± 0.752
0.0AspXaa: 0.0 ± 0.0
Glu
1.326GluAla: 1.326 ± 0.752
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
0.0GluGlu: 0.0 ± 0.0
3.979GluPhe: 3.979 ± 2.255
1.326GluGly: 1.326 ± 1.068
1.326GluHis: 1.326 ± 0.752
1.326GluIle: 1.326 ± 1.068
2.653GluLys: 2.653 ± 0.316
3.979GluLeu: 3.979 ± 3.204
1.326GluMet: 1.326 ± 0.752
5.305GluAsn: 5.305 ± 1.187
2.653GluPro: 2.653 ± 1.504
1.326GluGln: 1.326 ± 1.068
0.0GluArg: 0.0 ± 0.0
2.653GluSer: 2.653 ± 0.316
5.305GluThr: 5.305 ± 0.632
3.979GluVal: 3.979 ± 2.255
0.0GluTrp: 0.0 ± 0.0
1.326GluTyr: 1.326 ± 0.752
0.0GluXaa: 0.0 ± 0.0
Phe
1.326PheAla: 1.326 ± 0.752
2.653PheCys: 2.653 ± 1.504
1.326PheAsp: 1.326 ± 1.068
2.653PheGlu: 2.653 ± 1.504
0.0PhePhe: 0.0 ± 0.0
2.653PheGly: 2.653 ± 1.504
0.0PheHis: 0.0 ± 0.0
5.305PheIle: 5.305 ± 3.007
1.326PheLys: 1.326 ± 0.752
9.284PheLeu: 9.284 ± 3.836
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
5.305PhePro: 5.305 ± 1.187
2.653PheGln: 2.653 ± 1.504
2.653PheArg: 2.653 ± 0.316
5.305PheSer: 5.305 ± 4.272
1.326PheThr: 1.326 ± 0.752
1.326PheVal: 1.326 ± 0.752
0.0PheTrp: 0.0 ± 0.0
1.326PheTyr: 1.326 ± 1.068
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
1.326GlyAsp: 1.326 ± 0.752
1.326GlyGlu: 1.326 ± 1.068
0.0GlyPhe: 0.0 ± 0.0
0.0GlyGly: 0.0 ± 0.0
1.326GlyHis: 1.326 ± 0.752
1.326GlyIle: 1.326 ± 0.752
1.326GlyLys: 1.326 ± 0.752
1.326GlyLeu: 1.326 ± 1.068
0.0GlyMet: 0.0 ± 0.0
1.326GlyAsn: 1.326 ± 0.752
1.326GlyPro: 1.326 ± 0.752
1.326GlyGln: 1.326 ± 0.752
1.326GlyArg: 1.326 ± 0.752
1.326GlySer: 1.326 ± 0.752
3.979GlyThr: 3.979 ± 1.384
2.653GlyVal: 2.653 ± 0.316
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.326HisAsp: 1.326 ± 1.068
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.326HisGly: 1.326 ± 0.752
1.326HisHis: 1.326 ± 0.752
3.979HisIle: 3.979 ± 1.384
3.979HisLys: 3.979 ± 2.255
5.305HisLeu: 5.305 ± 0.632
0.0HisMet: 0.0 ± 0.0
1.326HisAsn: 1.326 ± 0.752
0.0HisPro: 0.0 ± 0.0
1.326HisGln: 1.326 ± 1.068
0.0HisArg: 0.0 ± 0.0
3.979HisSer: 3.979 ± 1.384
3.979HisThr: 3.979 ± 1.384
5.305HisVal: 5.305 ± 1.187
0.0HisTrp: 0.0 ± 0.0
5.305HisTyr: 5.305 ± 1.187
0.0HisXaa: 0.0 ± 0.0
Ile
1.326IleAla: 1.326 ± 1.068
1.326IleCys: 1.326 ± 0.752
3.979IleAsp: 3.979 ± 2.255
2.653IleGlu: 2.653 ± 1.504
5.305IlePhe: 5.305 ± 1.187
1.326IleGly: 1.326 ± 1.068
3.979IleHis: 3.979 ± 3.204
3.979IleIle: 3.979 ± 2.255
9.284IleLys: 9.284 ± 3.443
7.958IleLeu: 7.958 ± 2.768
2.653IleMet: 2.653 ± 0.316
3.979IleAsn: 3.979 ± 2.255
2.653IlePro: 2.653 ± 2.136
1.326IleGln: 1.326 ± 0.752
2.653IleArg: 2.653 ± 0.316
1.326IleSer: 1.326 ± 0.752
5.305IleThr: 5.305 ± 0.632
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
7.958IleTyr: 7.958 ± 2.691
0.0IleXaa: 0.0 ± 0.0
Lys
6.631LysAla: 6.631 ± 1.7
2.653LysCys: 2.653 ± 0.316
1.326LysAsp: 1.326 ± 0.752
2.653LysGlu: 2.653 ± 0.316
7.958LysPhe: 7.958 ± 0.871
0.0LysGly: 0.0 ± 0.0
2.653LysHis: 2.653 ± 0.316
9.284LysIle: 9.284 ± 3.443
2.653LysLys: 2.653 ± 1.504
9.284LysLeu: 9.284 ± 1.623
1.326LysMet: 1.326 ± 1.068
1.326LysAsn: 1.326 ± 0.752
5.305LysPro: 5.305 ± 0.632
3.979LysGln: 3.979 ± 2.255
1.326LysArg: 1.326 ± 0.752
3.979LysSer: 3.979 ± 1.384
6.631LysThr: 6.631 ± 0.119
2.653LysVal: 2.653 ± 2.136
0.0LysTrp: 0.0 ± 0.0
7.958LysTyr: 7.958 ± 2.691
0.0LysXaa: 0.0 ± 0.0
Leu
10.61LeuAla: 10.61 ± 1.265
1.326LeuCys: 1.326 ± 1.068
2.653LeuAsp: 2.653 ± 0.316
7.958LeuGlu: 7.958 ± 0.871
0.0LeuPhe: 0.0 ± 0.0
1.326LeuGly: 1.326 ± 0.752
1.326LeuHis: 1.326 ± 1.068
9.284LeuIle: 9.284 ± 3.836
14.589LeuLys: 14.589 ± 4.468
5.305LeuLeu: 5.305 ± 2.452
0.0LeuMet: 0.0 ± 0.0
10.61LeuAsn: 10.61 ± 0.555
10.61LeuPro: 10.61 ± 4.904
3.979LeuGln: 3.979 ± 1.384
2.653LeuArg: 2.653 ± 2.136
13.263LeuSer: 13.263 ± 3.4
9.284LeuThr: 9.284 ± 2.016
1.326LeuVal: 1.326 ± 1.068
0.0LeuTrp: 0.0 ± 0.0
2.653LeuTyr: 2.653 ± 0.316
0.0LeuXaa: 0.0 ± 0.0
Met
5.305MetAla: 5.305 ± 0.632
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.326MetGlu: 1.326 ± 0.752
1.326MetPhe: 1.326 ± 1.068
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.326MetLys: 1.326 ± 0.752
1.326MetLeu: 1.326 ± 1.068
2.653MetMet: 2.653 ± 0.594
1.326MetAsn: 1.326 ± 1.068
3.979MetPro: 3.979 ± 2.255
0.0MetGln: 0.0 ± 0.0
1.326MetArg: 1.326 ± 0.752
1.326MetSer: 1.326 ± 0.752
1.326MetThr: 1.326 ± 0.752
2.653MetVal: 2.653 ± 1.504
0.0MetTrp: 0.0 ± 0.0
2.653MetTyr: 2.653 ± 1.504
0.0MetXaa: 0.0 ± 0.0
Asn
3.979AsnAla: 3.979 ± 0.436
0.0AsnCys: 0.0 ± 0.0
1.326AsnAsp: 1.326 ± 0.752
1.326AsnGlu: 1.326 ± 0.752
2.653AsnPhe: 2.653 ± 0.316
2.653AsnGly: 2.653 ± 1.504
3.979AsnHis: 3.979 ± 0.436
6.631AsnIle: 6.631 ± 0.119
2.653AsnLys: 2.653 ± 0.316
7.958AsnLeu: 7.958 ± 0.871
1.326AsnMet: 1.326 ± 0.752
5.305AsnAsn: 5.305 ± 1.187
5.305AsnPro: 5.305 ± 0.632
0.0AsnGln: 0.0 ± 0.0
2.653AsnArg: 2.653 ± 0.316
6.631AsnSer: 6.631 ± 0.119
2.653AsnThr: 2.653 ± 0.316
5.305AsnVal: 5.305 ± 0.632
1.326AsnTrp: 1.326 ± 0.752
1.326AsnTyr: 1.326 ± 0.752
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.326ProCys: 1.326 ± 1.068
5.305ProAsp: 5.305 ± 0.632
3.979ProGlu: 3.979 ± 2.255
1.326ProPhe: 1.326 ± 0.752
1.326ProGly: 1.326 ± 1.068
1.326ProHis: 1.326 ± 0.752
3.979ProIle: 3.979 ± 1.384
10.61ProLys: 10.61 ± 1.265
3.979ProLeu: 3.979 ± 1.384
6.631ProMet: 6.631 ± 1.939
5.305ProAsn: 5.305 ± 1.187
5.305ProPro: 5.305 ± 1.187
1.326ProGln: 1.326 ± 1.068
6.631ProArg: 6.631 ± 1.939
2.653ProSer: 2.653 ± 2.136
2.653ProThr: 2.653 ± 1.504
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.326ProTyr: 1.326 ± 0.752
0.0ProXaa: 0.0 ± 0.0
Gln
1.326GlnAla: 1.326 ± 1.068
0.0GlnCys: 0.0 ± 0.0
3.979GlnAsp: 3.979 ± 1.384
1.326GlnGlu: 1.326 ± 0.752
1.326GlnPhe: 1.326 ± 0.752
0.0GlnGly: 0.0 ± 0.0
2.653GlnHis: 2.653 ± 1.504
1.326GlnIle: 1.326 ± 0.752
3.979GlnLys: 3.979 ± 0.436
7.958GlnLeu: 7.958 ± 0.871
0.0GlnMet: 0.0 ± 0.0
3.979GlnAsn: 3.979 ± 1.384
1.326GlnPro: 1.326 ± 0.752
0.0GlnGln: 0.0 ± 0.0
3.979GlnArg: 3.979 ± 0.436
0.0GlnSer: 0.0 ± 0.0
5.305GlnThr: 5.305 ± 0.632
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.326GlnTyr: 1.326 ± 1.068
0.0GlnXaa: 0.0 ± 0.0
Arg
2.653ArgAla: 2.653 ± 2.136
1.326ArgCys: 1.326 ± 0.752
1.326ArgAsp: 1.326 ± 0.752
1.326ArgGlu: 1.326 ± 0.752
2.653ArgPhe: 2.653 ± 1.504
0.0ArgGly: 0.0 ± 0.0
2.653ArgHis: 2.653 ± 0.316
2.653ArgIle: 2.653 ± 1.504
6.631ArgLys: 6.631 ± 0.119
6.631ArgLeu: 6.631 ± 1.7
2.653ArgMet: 2.653 ± 1.504
3.979ArgAsn: 3.979 ± 1.384
2.653ArgPro: 2.653 ± 0.316
1.326ArgGln: 1.326 ± 1.068
2.653ArgArg: 2.653 ± 1.504
3.979ArgSer: 3.979 ± 0.436
3.979ArgThr: 3.979 ± 2.255
1.326ArgVal: 1.326 ± 0.752
1.326ArgTrp: 1.326 ± 1.068
2.653ArgTyr: 2.653 ± 0.316
0.0ArgXaa: 0.0 ± 0.0
Ser
5.305SerAla: 5.305 ± 2.452
1.326SerCys: 1.326 ± 0.752
1.326SerAsp: 1.326 ± 0.752
3.979SerGlu: 3.979 ± 3.204
2.653SerPhe: 2.653 ± 1.504
3.979SerGly: 3.979 ± 0.436
1.326SerHis: 1.326 ± 1.068
5.305SerIle: 5.305 ± 0.632
6.631SerLys: 6.631 ± 1.7
11.936SerLeu: 11.936 ± 4.152
2.653SerMet: 2.653 ± 1.504
0.0SerAsn: 0.0 ± 0.0
5.305SerPro: 5.305 ± 1.187
7.958SerGln: 7.958 ± 0.871
7.958SerArg: 7.958 ± 0.948
7.958SerSer: 7.958 ± 0.871
2.653SerThr: 2.653 ± 2.136
1.326SerVal: 1.326 ± 0.752
0.0SerTrp: 0.0 ± 0.0
2.653SerTyr: 2.653 ± 2.136
0.0SerXaa: 0.0 ± 0.0
Thr
2.653ThrAla: 2.653 ± 0.316
1.326ThrCys: 1.326 ± 1.068
3.979ThrAsp: 3.979 ± 2.255
1.326ThrGlu: 1.326 ± 1.068
1.326ThrPhe: 1.326 ± 1.068
1.326ThrGly: 1.326 ± 1.068
3.979ThrHis: 3.979 ± 0.436
2.653ThrIle: 2.653 ± 0.316
2.653ThrLys: 2.653 ± 1.504
10.61ThrLeu: 10.61 ± 6.724
3.979ThrMet: 3.979 ± 0.436
3.979ThrAsn: 3.979 ± 0.436
3.979ThrPro: 3.979 ± 0.436
7.958ThrGln: 7.958 ± 0.948
3.979ThrArg: 3.979 ± 0.436
9.284ThrSer: 9.284 ± 1.623
7.958ThrThr: 7.958 ± 0.948
3.979ThrVal: 3.979 ± 1.384
0.0ThrTrp: 0.0 ± 0.0
1.326ThrTyr: 1.326 ± 1.068
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
1.326ValCys: 1.326 ± 0.752
1.326ValAsp: 1.326 ± 1.068
2.653ValGlu: 2.653 ± 0.316
5.305ValPhe: 5.305 ± 0.632
1.326ValGly: 1.326 ± 0.752
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
2.653ValLys: 2.653 ± 1.504
2.653ValLeu: 2.653 ± 0.316
1.326ValMet: 1.326 ± 0.752
6.631ValAsn: 6.631 ± 1.7
2.653ValPro: 2.653 ± 1.504
0.0ValGln: 0.0 ± 0.0
1.326ValArg: 1.326 ± 0.752
3.979ValSer: 3.979 ± 0.436
2.653ValThr: 2.653 ± 0.316
1.326ValVal: 1.326 ± 1.068
0.0ValTrp: 0.0 ± 0.0
1.326ValTyr: 1.326 ± 0.752
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.326TrpHis: 1.326 ± 0.752
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.326TrpArg: 1.326 ± 1.068
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.653TyrAla: 2.653 ± 0.316
0.0TyrCys: 0.0 ± 0.0
1.326TyrAsp: 1.326 ± 0.752
1.326TyrGlu: 1.326 ± 0.752
0.0TyrPhe: 0.0 ± 0.0
0.0TyrGly: 0.0 ± 0.0
1.326TyrHis: 1.326 ± 0.752
5.305TyrIle: 5.305 ± 1.187
5.305TyrLys: 5.305 ± 1.187
5.305TyrLeu: 5.305 ± 1.187
0.0TyrMet: 0.0 ± 0.0
6.631TyrAsn: 6.631 ± 1.939
0.0TyrPro: 0.0 ± 0.0
2.653TyrGln: 2.653 ± 0.316
3.979TyrArg: 3.979 ± 0.436
1.326TyrSer: 1.326 ± 0.752
6.631TyrThr: 6.631 ± 1.7
2.653TyrVal: 2.653 ± 0.316
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (755 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski